Robert M. Nerem - Publications

Affiliations: 
Biomedical Engineering Georgia Institute of Technology, Atlanta, GA 
Area:
Biomedical Engineering

168 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Esmerats JF, Villa-Roel N, Kumar S, Gu L, Salim MT, Ohh M, Taylor WR, Nerem RM, Yoganathan AP, Jo H. Disturbed Flow Increases UBE2C (Ubiquitin E2 Ligase C) via Loss of miR-483-3p, Inducing Aortic Valve Calcification by the HIF-1α (Hypoxia-Inducible Factor-1α) Pathway in Endothelial Cells. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA118312233. PMID 30602302 DOI: 10.1161/Atvbaha.118.312233  0.358
2016 Roh KH, Nerem RM, Roy K. Biomanufacturing of Therapeutic Cells: State of the Art, Current Challenges, and Future Perspectives. Annual Review of Chemical and Biomolecular Engineering. 7: 455-78. PMID 27276552 DOI: 10.1146/Annurev-Chembioeng-080615-033559  0.338
2015 Chien S, Bashir R, Nerem RM, Pettigrew R. Engineering as a new frontier for translational medicine. Science Translational Medicine. 7: 281fs13. PMID 25834106 DOI: 10.1126/Scitranslmed.Aaa4325  0.312
2015 Jo H, Hong M, Shim JB, Ankeny RF, Kim H, Nerem RM, Khang G. The role of demineralized bone particle in a PLGA scaffold designed to create a media equivalent for a tissue engineered blood vessel Macromolecular Research. 23: 986-993. DOI: 10.1007/S13233-015-3138-6  0.391
2014 Shim JB, Ankeny RF, Kim H, Nerem RM, Khang G. A study of a three-dimensional PLGA sponge containing natural polymers co-cultured with endothelial and mesenchymal stem cells as a tissue engineering scaffold. Biomedical Materials (Bristol, England). 9: 045015. PMID 25065725 DOI: 10.1088/1748-6041/9/4/045015  0.491
2014 Nerem RM. Stem cell engineering. Tissue Engineering. Part A. 20: 893-4. PMID 24527967 DOI: 10.1089/Ten.Tea.2013.0764  0.396
2014 Bao G, Nerem RM. Frontiers in bioengineering research. Annals of Biomedical Engineering. 42: 241-2. PMID 24510229 DOI: 10.1007/S10439-014-0982-Z  0.34
2014 Loring JF, McDevitt TC, Palecek SP, Schaffer DV, Zandstra PW, Nerem RM. A global assessment of stem cell engineering. Tissue Engineering. Part A. 20: 2575-89. PMID 24428577 DOI: 10.1089/Ten.Tea.2013.0468  0.36
2014 Nsiah BA, Ahsan T, Griffiths S, Cooke M, Nerem RM, McDevitt TC. Fluid shear stress pre-conditioning promotes endothelial morphogenesis of embryonic stem cells within embryoid bodies. Tissue Engineering. Part A. 20: 954-65. PMID 24138406 DOI: 10.1089/Ten.Tea.2013.0243  0.475
2013 Hong M, Jo H, Ankeny RF, Holliday-Ankeny CJ, Kim H, Khang G, Nerem RM. Influence of mesenchymal stem cells on the response of endothelial cells to laminar flow and shear stress. Cells, Tissues, Organs. 198: 289-99. PMID 24335258 DOI: 10.1159/000356319  0.54
2013 Healy KE, McDevitt TC, Murphy WL, Nerem RM. Engineering the emergence of stem cell therapeutics. Science Translational Medicine. 5: 207ed17. PMID 24132634 DOI: 10.1126/Scitranslmed.3007609  0.333
2013 Griffiths S, Baraniak PR, Copland IB, Nerem RM, McDevitt TC. Human platelet lysate stimulates high-passage and senescent human multipotent mesenchymal stromal cell growth and rejuvenation in vitro. Cytotherapy. 15: 1469-83. PMID 23981539 DOI: 10.1016/J.Jcyt.2013.05.020  0.349
2013 Ferdous Z, Jo H, Nerem RM. Strain magnitude-dependent calcific marker expression in valvular and vascular cells. Cells, Tissues, Organs. 197: 372-83. PMID 23548742 DOI: 10.1159/000347007  0.457
2013 Pineda ET, Nerem RM, Ahsan T. Differentiation patterns of embryonic stem cells in two- versus three-dimensional culture. Cells, Tissues, Organs. 197: 399-410. PMID 23406658 DOI: 10.1159/000346166  0.404
2013 Ankeny RF, Hinds MT, Nerem RM. Dynamic shear stress regulation of inflammatory and thrombotic pathways in baboon endothelial outgrowth cells. Tissue Engineering. Part A. 19: 1573-82. PMID 23406430 DOI: 10.1089/Ten.Tea.2012.0300  0.477
2013 Ankeny RF, Nerem RM. Regulation of thrombotic and inflammatory responses in baboon endothelial outgrowth cells under various hemodynamic conditions Cardiovascular Pathology. 22: e38. DOI: 10.1016/J.Carpath.2013.01.038  0.379
2012 Wolfe RP, Leleux J, Nerem RM, Ahsan T. Effects of shear stress on germ lineage specification of embryonic stem cells. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 1263-73. PMID 22968330 DOI: 10.1039/C2Ib20040F  0.37
2012 Ankeny RF, Ankeny CJ, Nerem RM, Jo H. Maturing EPCs into endothelial cells: may the force be with the EPCs: focus on "Fluid shear stress induces differentiation of circulating phenotype endothelial progenitor cells". American Journal of Physiology. Cell Physiology. 303: C589-91. PMID 22763124 DOI: 10.1152/Ajpcell.00224.2012  0.515
2012 Ensley AE, Nerem RM, Anderson DE, Hanson SR, Hinds MT. Fluid shear stress alters the hemostatic properties of endothelial outgrowth cells. Tissue Engineering. Part A. 18: 127-36. PMID 21787250 DOI: 10.1089/Ten.Tea.2010.0290  0.799
2011 Schenke-Layland K, Nerem RM. In vitro human tissue models--moving towards personalized regenerative medicine. Advanced Drug Delivery Reviews. 63: 195-6. PMID 21600252 DOI: 10.1016/J.Addr.2011.05.001  0.442
2011 Ferdous Z, Jo H, Nerem RM. Differences in valvular and vascular cell responses to strain in osteogenic media. Biomaterials. 32: 2885-93. PMID 21284997 DOI: 10.1016/J.Biomaterials.2011.01.030  0.519
2011 Nerem RM, Sambanis A. Tissue engineering: from biology to biological substitutes. Tissue Engineering. 1: 3-13. PMID 19877911 DOI: 10.1089/Ten.1995.1.3  0.47
2011 Nerem RM. Tissue engineering: From basic biology to cell-based applications Stem Cell and Tissue Engineering. 1-12. DOI: 10.1142/9789814317061_0001  0.381
2011 Ankeny RF, Nerem RM. Shear stress effects on the inflammation and thrombogenic state of baboon endothelial outgrowth cells Asme 2011 Summer Bioengineering Conference, Sbc 2011. 1139-1140. DOI: 10.1115/SBC2011-53126  0.303
2010 Schutte SC, Chen Z, Brockbank KG, Nerem RM. Tissue engineering of a collagen-based vascular media: Demonstration of functionality. Organogenesis. 6: 204-11. PMID 21220958 DOI: 10.4161/Org.6.4.12651  0.82
2010 Ahsan T, Nerem RM. Fluid shear stress promotes an endothelial-like phenotype during the early differentiation of embryonic stem cells. Tissue Engineering. Part A. 16: 3547-53. PMID 20666609 DOI: 10.1089/Ten.Tea.2010.0014  0.466
2010 Schutte SC, Chen Z, Brockbank KG, Nerem RM. Cyclic strain improves strength and function of a collagen-based tissue-engineered vascular media. Tissue Engineering. Part A. 16: 3149-57. PMID 20504073 DOI: 10.1089/Ten.Tea.2010.0009  0.812
2010 Duffy GP, D'Arcy S, Ahsan T, Nerem RM, O'Brien T, Barry F. Mesenchymal stem cells overexpressing ephrin-b2 rapidly adopt an early endothelial phenotype with simultaneous reduction of osteogenic potential. Tissue Engineering. Part A. 16: 2755-68. PMID 20491587 DOI: 10.1089/Ten.Tea.2009.0623  0.473
2010 Badylak SF, Nerem RM. Progress in tissue engineering and regenerative medicine. Proceedings of the National Academy of Sciences of the United States of America. 107: 3285-6. PMID 20181571 DOI: 10.1073/Pnas.1000256107  0.449
2010 Gauvin R, Ahsan T, Larouche D, Lévesque P, Dubé J, Auger FA, Nerem RM, Germain L. A novel single-step self-assembly approach for the fabrication of tissue-engineered vascular constructs. Tissue Engineering. Part A. 16: 1737-47. PMID 20038201 DOI: 10.1089/Ten.Tea.2009.0313  0.572
2010 Ferdous Z, Jo H, Nerem RM. Differential osteogenic marker expression by human vascular and valvular cells in tissue-engineered collagen constructs Asme 2010 Summer Bioengineering Conference, Sbc 2010. 639-640. DOI: 10.1115/SBC2010-19424  0.44
2009 Butler DL, Goldstein SA, Guldberg RE, Guo XE, Kamm R, Laurencin CT, McIntire LV, Mow VC, Nerem RM, Sah RL, Soslowsky LJ, Spilker RL, Tranquillo RT. The impact of biomechanics in tissue engineering and regenerative medicine. Tissue Engineering. Part B, Reviews. 15: 477-84. PMID 19583462 DOI: 10.1089/Ten.Teb.2009.0340  0.463
2009 Duffy GP, Ahsan T, O'Brien T, Barry F, Nerem RM. Bone marrow-derived mesenchymal stem cells promote angiogenic processes in a time- and dose-dependent manner in vitro. Tissue Engineering. Part A. 15: 2459-70. PMID 19327020 DOI: 10.1089/Ten.Tea.2008.0341  0.401
2009 Doyle AM, Nerem RM, Ahsan T. Human mesenchymal stem cells form multicellular structures in response to applied cyclic strain. Annals of Biomedical Engineering. 37: 783-93. PMID 19184434 DOI: 10.1007/S10439-009-9644-Y  0.391
2009 Ahsan T, Doyle AM, Nerem RM. Stem cells, biomechanics, and Y. C. Fung Tributes to Yuan-Cheng Fung On His 90th Birthday: Biomechanics: From Molecules to Man. 185-192. DOI: 10.1142/9789814289955_0016  0.324
2008 Gao J, Crapo P, Nerem R, Wang Y. Co-expression of elastin and collagen leads to highly compliant engineered blood vessels. Journal of Biomedical Materials Research. Part A. 85: 1120-8. PMID 18412137 DOI: 10.1002/Jbm.A.32028  0.552
2008 Han JW, Shimada K, Ma-Krupa W, Johnson TL, Nerem RM, Goronzy JJ, Weyand CM. Vessel wall-embedded dendritic cells induce T-cell autoreactivity and initiate vascular inflammation. Circulation Research. 102: 546-53. PMID 18202318 DOI: 10.1161/Circresaha.107.161653  0.41
2008 Hinds MT, Ma M, Tran N, Ensley AE, Kladakis SM, Vartanian KB, Markway BD, Nerem RM, Hanson SR. Potential of baboon endothelial progenitor cells for tissue engineered vascular grafts. Journal of Biomedical Materials Research. Part A. 86: 804-12. PMID 18041726 DOI: 10.1002/Jbm.A.31672  0.808
2007 Hellman KB, Nerem RM. Editorial: advancing tissue engineering and regenerative medicine. Tissue Engineering. 13: 2823-4. PMID 18021010 DOI: 10.1089/Ten.2007.1504  0.39
2007 Johnson TL, Nerem RM. Endothelial connexin 37, connexin 40, and connexin 43 respond uniquely to substrate and shear stress. Endothelium : Journal of Endothelial Cell Research. 14: 215-26. PMID 17922338 DOI: 10.1080/10623320701617233  0.435
2007 Nerem RM. Cell-based therapies: from basic biology to replacement, repair, and regeneration. Biomaterials. 28: 5074-7. PMID 17689607 DOI: 10.1016/J.Biomaterials.2007.07.032  0.396
2007 Gao J, Ensley AE, Nerem RM, Wang Y. Poly(glycerol sebacate) supports the proliferation and phenotypic protein expression of primary baboon vascular cells. Journal of Biomedical Materials Research. Part A. 83: 1070-5. PMID 17584900 DOI: 10.1002/Jbm.A.31434  0.825
2007 Butcher JT, Nerem RM. Valvular endothelial cells and the mechanoregulation of valvular pathology. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 362: 1445-57. PMID 17569641 DOI: 10.1098/Rstb.2007.2127  0.674
2007 Simpson D, Liu H, Fan TH, Nerem R, Dudley SC. A tissue engineering approach to progenitor cell delivery results in significant cell engraftment and improved myocardial remodeling. Stem Cells (Dayton, Ohio). 25: 2350-7. PMID 17525236 DOI: 10.1634/Stemcells.2007-0132  0.414
2006 McCloskey KE, Smith DA, Jo H, Nerem RM. Embryonic stem cell-derived endothelial cells may lack complete functional maturation in vitro. Journal of Vascular Research. 43: 411-21. PMID 16877873 DOI: 10.1159/000094791  0.449
2006 McCloskey KE, Stice SL, Nerem RM. In vitro derivation and expansion of endothelial cells from embryonic stem cells. Methods in Molecular Biology (Clifton, N.J.). 330: 287-301. PMID 16846032 DOI: 10.1385/1-59745-036-7:287  0.45
2006 Butcher JT, Barrett BC, Nerem RM. Equibiaxial strain stimulates fibroblastic phenotype shift in smooth muscle cells in an engineered tissue model of the aortic wall. Biomaterials. 27: 5252-8. PMID 16806457 DOI: 10.1016/J.Biomaterials.2006.05.040  0.652
2006 Nerem RM. Tissue engineering: the hope, the hype, and the future. Tissue Engineering. 12: 1143-50. PMID 16771630 DOI: 10.1089/Ten.2006.12.1143  0.434
2006 Butcher JT, Nerem RM. Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: effects of steady shear stress. Tissue Engineering. 12: 905-15. PMID 16674302 DOI: 10.1089/Ten.2006.12.905  0.711
2006 Butcher JT, Tressel S, Johnson T, Turner D, Sorescu G, Jo H, Nerem RM. Transcriptional profiles of valvular and vascular endothelial cells reveal phenotypic differences: influence of shear stress. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 69-77. PMID 16293796 DOI: 10.1161/01.Atv.0000196624.70507.0D  0.674
2006 Nerem R. The vascular endothelial cell: from basic research to a vascular implant Journal of Biomechanics. 39: S303. DOI: 10.1016/S0021-9290(06)84182-5  0.312
2006 Johnson TL, Barabino GA, Nerem RM. Engineering more physiologic in vitro models for the study of vascular biology Progress in Pediatric Cardiology. 21: 201-210. DOI: 10.1016/J.Ppedcard.2005.11.011  0.599
2005 Berglund JD, Nerem RM, Sambanis A. Viscoelastic testing methodologies for tissue engineered blood vessels. Journal of Biomechanical Engineering. 127: 1176-84. PMID 16502660 DOI: 10.1115/1.2073487  0.809
2005 Elder E, Chen Z, Ensley A, Nerem R, Brockbank K, Song Y. Enhanced tissue strength in cryopreserved, collagen-based blood vessel constructs. Transplantation Proceedings. 37: 4625-9. PMID 16387185 DOI: 10.1016/j.transproceed.2005.10.033  0.793
2005 Ahsan T, Nerem RM. Bioengineered tissues: The science, the technology, and the industry Orthodontics and Craniofacial Research. 8: 134-140. PMID 16022714 DOI: 10.1111/J.1601-6343.2005.00326.X  0.384
2005 Stegemann JP, Hong H, Nerem RM. Mechanical, biochemical, and extracellular matrix effects on vascular smooth muscle cell phenotype. Journal of Applied Physiology (Bethesda, Md. : 1985). 98: 2321-7. PMID 15894540 DOI: 10.1152/Japplphysiol.01114.2004  0.51
2005 McCloskey KE, Gilroy ME, Nerem RM. Use of embryonic stem cell-derived endothelial cells as a cell source to generate vessel structures in vitro. Tissue Engineering. 11: 497-505. PMID 15869428 DOI: 10.1089/Ten.2005.11.497  0.511
2004 Berglund JD, Nerem RM, Sambanis A. Incorporation of intact elastin scaffolds in tissue-engineered collagen-based vascular grafts. Tissue Engineering. 10: 1526-35. PMID 15588412 DOI: 10.1089/Ten.2004.10.1526  0.824
2004 Butcher JT, Nerem RM. Porcine aortic valve interstitial cells in three-dimensional culture: comparison of phenotype with aortic smooth muscle cells. The Journal of Heart Valve Disease. 13: 478-85; discussion 4. PMID 15222296  0.652
2004 Nerem RM. Tissue engineering of the vascular system Vox Sanguinis, Supplement. 87. PMID 15209905 DOI: 10.1111/J.1741-6892.2004.00476.X  0.508
2004 Kladakis SM, Nerem RM. Endothelial cell monolayer formation: effect of substrate and fluid shear stress. Endothelium : Journal of Endothelial Cell Research. 11: 29-44. PMID 15203877 DOI: 10.1080/10623320490432461  0.828
2004 Butcher JT, Penrod AM, García AJ, Nerem RM. Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1429-34. PMID 15117733 DOI: 10.1161/01.Atv.0000130462.50769.5A  0.704
2004 Cummings CL, Gawlitta D, Nerem RM, Stegemann JP. Properties of engineered vascular constructs made from collagen, fibrin, and collagen-fibrin mixtures. Biomaterials. 25: 3699-706. PMID 15020145 DOI: 10.1016/J.Biomaterials.2003.10.073  0.505
2004 Stegemann JP, Dey NB, Lincoln TM, Nerem RM. Genetic modification of smooth muscle cells to control phenotype and function in vascular tissue engineering. Tissue Engineering. 10: 189-99. PMID 15009945 DOI: 10.1089/107632704322791844  0.513
2004 Nerem RM, Ensley AE. The tissue engineering of blood vessels and the heart. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 4: 36-42. PMID 14871272 DOI: 10.1111/J.1600-6135.2004.0343.X  0.779
2004 Citron P, Nerem RM. Bioengineering: 25 years of progress-but still only a beginning Technology in Society. 26: 415-431. DOI: 10.1016/J.Techsoc.2004.01.008  0.302
2004 Nerem RM. Critical issues in vascular tissue engineering International Congress Series. 1262: 122-125. DOI: 10.1016/j.ics.2003.12.029  0.402
2004 Butcher J, Nerem R. MICROARRAY ANALYSIS REVEALS PHENOTYPIC DIFFERENCES BETWEEN VALVULAR AND VASCULAR ENDOTHELIAL CELLS IN STATIC AND FLUID FLOW ENVIRONMENTS Cardiovascular Pathology. 13: 124. DOI: 10.1016/J.Carpath.2004.03.375  0.651
2004 Johnson TL, Nerem RM. ENDOTHELIAL CELL CONNEXIN EXPRESSION: INFLUENCE OF SUBSTRATE AND SHEAR STRESS Cardiovascular Pathology. 13: 39-40. DOI: 10.1016/J.Carpath.2004.03.111  0.428
2004 Ensley AE, Haller JM, Nerem RM. Evaluation of naturally derived scaffolds for vascular tissue engineering: The role of collagen, fibrin and small intestinal submucosa Transactions - 7th World Biomaterials Congress. 198.  0.821
2003 McCloskey KE, Lyons I, Rao RR, Stice SL, Nerem RM. Purified and proliferating endothelial cells derived and expanded in vitro from embryonic stem cells. Endothelium : Journal of Endothelial Cell Research. 10: 329-36. PMID 14741848 DOI: 10.1080/10623320390272325  0.446
2003 Seliktar D, Nerem RM, Galis ZS. Mechanical strain-stimulated remodeling of tissue-engineered blood vessel constructs. Tissue Engineering. 9: 657-66. PMID 13678444 DOI: 10.1089/107632703768247359  0.688
2003 Nerem RM. Tissue engineering: confronting the transplantation crisis. Advances in Experimental Medicine and Biology. 534: 1-9. PMID 12903707 DOI: 10.1007/978-1-4615-0063-6_1  0.381
2003 Stegemann JP, Nerem RM. Phenotype modulation in vascular tissue engineering using biochemical and mechanical stimulation. Annals of Biomedical Engineering. 31: 391-402. PMID 12723680 DOI: 10.1114/1.1558031  0.504
2003 Stegemann JP, Nerem RM. Altered response of vascular smooth muscle cells to exogenous biochemical stimulation in two- and three-dimensional culture. Experimental Cell Research. 283: 146-55. PMID 12581735 DOI: 10.1016/S0014-4827(02)00041-1  0.506
2003 Asanuma K, Magid R, Johnson C, Nerem RM, Galis ZS. Uniaxial strain upregulates matrix-degrading enzymes produced by human vascular smooth muscle cells. American Journal of Physiology. Heart and Circulatory Physiology. 284: H1778-84. PMID 12543633 DOI: 10.1152/Ajpheart.00494.2002  0.35
2003 Berglund JD, Mohseni MM, Nerem RM, Sambanis A. A biological hybrid model for collagen-based tissue engineered vascular constructs. Biomaterials. 24: 1241-54. PMID 12527265 DOI: 10.1016/S0142-9612(02)00506-9  0.831
2003 Nerem RM. Role of mechanics in vascular tissue engineering. Biorheology. 40: 281-7. PMID 12454417  0.438
2003 Nerem RM, Ratner BD. Launching TESNA: The Tissue Engineering Society North America Tissue Engineering. 9: 869-870. DOI: 10.1089/107632703322495510  0.396
2002 Imberti B, Seliktar D, Nerem RM, Remuzzi A. The response of endothelial cells to fluid shear stress using a co-culture model of the arterial wall. Endothelium : Journal of Endothelial Cell Research. 9: 11-23. PMID 12901357 DOI: 10.1080/10623320210714  0.696
2002 Braddon LG, Karoyli D, Harrison DG, Nerem RM. Maintenance of a functional endothelial cell monolayer on a fibroblast/polymer substrate under physiologically relevant shear stress conditions. Tissue Engineering. 8: 695-708. PMID 12202008 DOI: 10.1089/107632702760240607  0.481
2002 Malaviya P, Nerem RM. Fluid-induced shear stress stimulates chondrocyte proliferation partially mediated via TGF-beta1. Tissue Engineering. 8: 581-90. PMID 12201998 DOI: 10.1089/107632702760240508  0.343
2002 Cui ZF, Dykhuizen RC, Nerem RM, Sembanis A. Modeling of cryopreservation of engineered tissues with one-dimensional geometry Biotechnology Progress. 18: 354-361. PMID 11934307 DOI: 10.1021/Bp0101886  0.445
2002 Hunter CJ, Imler SM, Malaviya P, Nerem RM, Levenston ME. Mechanical compression alters gene expression and extracellular matrix synthesis by chondrocytes cultured in collagen I gels. Biomaterials. 23: 1249-59. PMID 11791929 DOI: 10.1016/S0142-9612(01)00245-9  0.388
2002 Kladakis SM, Nerem RM. Role of proliferation in endothelial cell monolayer formation Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 771-772.  0.825
2002 Butcher JT, Nerem RM. Morphological differences between aortic and aortic valve endothelial cells in static and fluid flow conditions Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 318-319.  0.661
2002 Ensley AE, Berglund JD, Nerem RM. Evaluation of collagen-elastin hybrid tissue engineered vascular constructs Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 864-865.  0.807
2002 Stegemann JP, Cummings CL, Gawlitta D, Nerem RM. Collagen, fibrin and collagen-fibrin mixtures as matrix materials for vascular tissue engineering Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 817-818.  0.335
2001 Seliktar D, Nerem RM, Galis ZS. The role of matrix metalloproteinase-2 in the remodeling of cell-seeded vascular constructs subjected to cyclic strain. Annals of Biomedical Engineering. 29: 923-34. PMID 11791675 DOI: 10.1114/1.1415522  0.676
2001 Fisher AB, Chien S, Barakat AI, Nerem RM. Endothelial cellular response to altered shear stress American Journal of Physiology - Lung Cellular and Molecular Physiology. 281. PMID 11504676 DOI: 10.1152/Ajplung.2001.281.3.L529  0.445
2001 Nerem RM, Seliktar D. Vascular tissue engineering. Annual Review of Biomedical Engineering. 3: 225-43. PMID 11447063 DOI: 10.1146/Annurev.Bioeng.3.1.225  0.708
2001 Kladakis SM, Nerem RM. Endothelial cell migration characteristics on a tissue engineered model of the vascular wall American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 50: 661-662.  0.83
2000 Nerem RM. Pierre M. Galletti: a personal reflection Annual Review of Biomedical Engineering. 2. PMID 11701504 DOI: 10.1146/Annurev.Bioeng.2.1.1  0.31
2000 Seliktar D, Black RA, Vito RP, Nerem RM. Dynamic mechanical conditioning of collagen-gel blood vessel constructs induces remodeling in vitro. Annals of Biomedical Engineering. 28: 351-62. PMID 10870892 DOI: 10.1114/1.275  0.709
2000 Nerem RM. Tissue Engineering a Blood Vessel Substitute: The Role of Biomechanics Yonsei Medical Journal. 41: 735-739. DOI: 10.3349/Ymj.2000.41.6.735  0.492
2000 Nerem RM. Hemodynamics, vascular biology, and atherosclerosis American Society of Mechanical Engineers, Applied Mechanics Division, Amd. 242: 77-82.  0.307
2000 Seliktar D, Galis ZS, Nerem RM. Dynamic mechanical conditioning regulates in vitro development of cell-seeded collagen constructs: The role of matrix metalloproteinases Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling. 56.  0.604
1999 Nerem R. Tissue Engineering of Vascular Prosthetic Grafts Nature Medicine. 5: 1118-1118. PMID 10502804 DOI: 10.1038/13434  0.496
1999 Nerem RM. Development of vascular substitutes Materials Research Society Symposium - Proceedings. 550: 293-296. DOI: 10.1557/Proc-550-293  0.499
1999 Sprague EA, Mohan S, Nerem RM. Shear Stress Regulation of Monocyte/Endothelial Interactions Journal of Vascular and Interventional Radiology. 10: 977-979. DOI: 10.1016/S1051-0443(99)70164-8  0.373
1999 Seliktar D, Galis ZS, Nerem RM. Cyclic mechanical strain stimulates in vitro remodeling of tissue engineered vascular grafts Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 126.  0.632
1998 De Keulenaer GW, Chappell DC, Ishizaka N, Nerem RM, Alexander RW, Griendling KK. Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase. Circulation Research. 82: 1094-101. PMID 9622162 DOI: 10.1161/01.Res.82.10.1094  0.395
1998 Chappell DC, Varner SE, Nerem RM, Medford RM, Alexander RW. Oscillatory shear stress stimulates adhesion molecule expression in cultured human endothelium. Circulation Research. 82: 532-9. PMID 9529157 DOI: 10.1161/01.RES.82.5.532  0.343
1998 Nerem RM, Alexander RW, Chappell DC, Medford RM, Varner SE, Robert Taylor W. The Study of the Influence of Flow on Vascular Endothelial Biology The American Journal of the Medical Sciences. 316: 169-175. DOI: 10.1016/S0002-9629(15)40397-0  0.512
1997 Howard AB, Alexander RW, Nerem RM, Griendling KK, Taylor WR. Cyclic strain induces an oxidative stress in endothelial cells. The American Journal of Physiology. 272: C421-7. PMID 9124284 DOI: 10.1152/Ajpcell.1997.272.2.C421  0.353
1997 Wiesner TF, Berk BC, Nerem RM. A mathematical model of the cytosolic-free calcium response in endothelial cells to fluid shear stress Proceedings of the National Academy of Sciences of the United States of America. 94: 3726-3731. PMID 9108045 DOI: 10.1073/Pnas.94.8.3726  0.339
1997 Varner SE, Chappell DC, Wayne Alexander R, Medford RM, Nerem RM. 4.W19.3 Endothelial VCAM-1 regulation by steady and oscillatory shear stress Atherosclerosis. 134: 288. DOI: 10.1016/S0021-9150(97)89491-9  0.384
1997 Nerem RM. Tissue engineering and the vascular system American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 35: 287-288.  0.412
1996 Sato M, Ohshima N, Nerem RM. Viscoelastic properties of cultured porcine aortic endothelial cells exposed to shear stress Journal of Biomechanics. 29: 461-467. PMID 8964775 DOI: 10.1016/0021-9290(95)00069-0  0.465
1996 Inoue N, Ramasamy S, Fukai T, Nerem RM, Harrison DG. Shear stress modulates expression of Cu/Zn superoxide dismutase in human aortic endothelial cells. Circulation Research. 79: 32-7. PMID 8925565 DOI: 10.1161/01.Res.79.1.32  0.375
1996 Corson MA, James NL, Latta SE, Nerem RM, Berk BC, Harrison DG. Phosphorylation of endothelial nitric oxide synthase in response to fluid shear stress. Circulation Research. 79: 984-91. PMID 8888690 DOI: 10.1161/01.Res.79.5.984  0.342
1996 Helmlinger G, Berk BC, Nerem RM. Pulsatile and steady flow-induced calcium oscillations in single cultured endothelial cells Journal of Vascular Research. 33: 360-369. PMID 8862141 DOI: 10.1159/000159164  0.309
1995 Galletti PM, Hellman KB, Nerem RM. Tissue engineering: from basic science to products: a preface. Tissue Engineering. 1: 147-9. PMID 19877923 DOI: 10.1089/Ten.1995.1.147  0.389
1995 Uematsu M, Ohara Y, Navas JP, Nishida K, Murphy TJ, Alexander RW, Nerem RM, Harrison DG. Regulation of endothelial cell nitric oxide synthase mRNA expression by shear stress. The American Journal of Physiology. 269: C1371-8. PMID 8572165 DOI: 10.1152/Ajpcell.1995.269.6.C1371  0.37
1995 Thoumine O, Nerem RM, Girard FR. Oscillatory shear stress and hydrostatic pressure modulate cell-matrix attachment proteins in cultured endothelial cells In Vitro Cellular &Amp; Developmental Biology - Animal. 31: 45-54. PMID 7704333 DOI: 10.1007/BF02631337  0.342
1995 Helmlinger G, Berk BC, Nerem RM. Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ American Journal of Physiology - Cell Physiology. 269. PMID 7653519 DOI: 10.1152/Ajpcell.1995.269.2.C367  0.334
1995 Thoumine O, Ziegler T, Girard PR, Nerem RM. Elongation of confluent endothelial cells in culture: The importance of fields of force in the associated alterations of their cytoskeletal structure Experimental Cell Research. 219: 427-441. PMID 7641794 DOI: 10.1006/Excr.1995.1249  0.452
1995 Ziegler T, Alexander RW, Nerem RM. An endothelial cell-smooth muscle cell co-culture model for use in the investigation of flow effects on vascular biology Annals of Biomedical Engineering. 23: 216-225. PMID 7631978 DOI: 10.1007/Bf02584424  0.494
1995 James NL, Harrison DG, Nerem RM. Effects of shear on endothelial cell calcium in the presence and absence of ATP Faseb Journal. 9: 968-973. PMID 7615166 DOI: 10.1096/Fasebj.9.10.7615166  0.408
1995 Girard PR, Nerem RM. Shear stress modulates endothelial cell morphology and F-actin organization through the regulation of focal adhesion-associated proteins Journal of Cellular Physiology. 163: 179-193. PMID 7534769 DOI: 10.1002/Jcp.1041630121  0.352
1995 Thoumine O, Nerem RM, Girard PR. Changes in organization and composition of the extracellular matrix underlying cultured endothelial cells exposed to laminar steady shear stress Laboratory Investigation. 73: 565-576. PMID 7474929  0.379
1995 Ziegler T, Robinson KA, Alexander RW, Nerem RM. Co-culture of endothelial cells and smooth muscle cells in a flow environment: An improved culture model of the vascular wall? Cells and Materials. 5: 115-124.  0.391
1994 Ziegler T, Nerem RM. Effect of flow on the process of endothelial cell division Arteriosclerosis and Thrombosis. 14: 636-643. PMID 8148361 DOI: 10.1161/01.Atv.14.4.636  0.433
1994 Ziegler T, Nerem RM. Tissue engineering a blood vessel: Regulation of vascular biology by mechanical stresses Journal of Cellular Biochemistry. 56: 204-209. PMID 7829582 DOI: 10.1002/Jcb.240560215  0.582
1993 Prasad ARS, Logan SA, Nerem RM, Schwartz CJ, Sprague EA. Flow-related responses of intracellular inositol phosphate levels in cultured aortic endothelial cells Circulation Research. 72: 827-836. PMID 8443870 DOI: 10.1161/01.Res.72.4.827  0.433
1993 Mitsumata M, Fishel RS, Nerem RM, Alexander RW, Berk BC. Fluid shear stress stimulates platelet-derived growth factor expression in endothelial cells American Journal of Physiology - Heart and Circulatory Physiology. 265. PMID 8342646 DOI: 10.1152/Ajpheart.1993.265.1.H3  0.391
1993 Nerem RM. Hemodynamics and the vascular endothelium Journal of Biomechanical Engineering. 115: 510-514. PMID 8302033 DOI: 10.1115/1.2895532  0.501
1993 Nerem RM, Harrison DG, Taylor WR, Alexander RW. Hemodynamics and vascular endothelial biology Journal of Cardiovascular Pharmacology. 21. PMID 7681132 DOI: 10.1097/00005344-199321001-00002  0.477
1993 Taylor WR, Nerem RM, Alexander RW. Polarized secretion of IGF-I and IGF-I binding protein activity by cultured aortic endothelial cells Journal of Cellular Physiology. 154: 139-142. PMID 7678264 DOI: 10.1002/Jcp.1041540117  0.418
1993 MITSUMATA M, YOSHIDA Y, NEREM RM, ALEXANDER RW, BERK BC. Effects of Shear Stress on Endothelial Cell Functions The Journal of Japan Atherosclerosis Society. 21: 473-477. DOI: 10.5551/Jat1973.21.6-7_473  0.43
1992 Geiger RV, Berk BC, Alexander RW, Nerem RM. Flow-induced calcium transients in single endothelial cells: Spatial and temporal analysis American Journal of Physiology - Cell Physiology. 262. PMID 1616008 DOI: 10.1152/Ajpcell.1992.262.6.C1411  0.33
1992 Oldham CD, Li C, Girard PR, Nerem RM, May SW. Peptide amidating enzymes are present in cultured endothelial cells Biochemical and Biophysical Research Communications. 184: 323-329. PMID 1567439 DOI: 10.1016/0006-291X(92)91196-W  0.374
1992 Nerem RM. Vascular fluid mechanics, the arterial wall, and atherosclerosis Journal of Biomechanical Engineering. 114: 274-282. PMID 1522720 DOI: 10.1115/1.2891384  0.482
1992 Nerem RM. Tissue engineering in the USA Medical &Amp; Biological Engineering &Amp; Computing. 30. PMID 1487936 DOI: 10.1007/BF02446171  0.363
1992 Nishida K, Harrison DG, Navas JP, Fisher AA, Dockery SP, Uematsu M, Nerem RM, Alexander RW, Murphy TJ. Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. The Journal of Clinical Investigation. 90: 2092-6. PMID 1385480 DOI: 10.1172/Jci116092  0.397
1991 Perktold K, Nerem RM, Peter RO. A numerical calculation of flow in a curved tube model of the left main coronary artery Journal of Biomechanics. 24: 175-189. PMID 2055907 DOI: 10.1016/0021-9290(91)90176-N  0.309
1991 Schwartz CJ, Valente AJ, Sprague EA, Kelley JL, Nerem RM. The pathogenesis of atherosclerosis: An overview Clinical Cardiology. 14. PMID 2044253 DOI: 10.1002/Clc.4960141302  0.382
1991 Helmlinger G, Geiger RV, Schreck S, Nerem RM. Effects of pulsatile flow on cultured vascular endothelial cell morphology Journal of Biomechanical Engineering. 113: 123-131. PMID 1875686 DOI: 10.1115/1.2891226  0.429
1991 Nerem RM. Cellular engineering Annals of Biomedical Engineering. 19: 529-545. PMID 1741530 DOI: 10.1007/BF02367396  0.329
1991 Girard PR, Nerem RM. Fluid shear stress alters endothelial cell structure through the regulation of focal contact-associated proteins American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 20: 425-427.  0.309
1990 Nerem RM. Vascular endothelial responses to shear stress Monographs On Atherosclerosis. 15: 117-124. PMID 2404192  0.312
1990 Sato M, Levesque MJ, Nerem RM, Ohshima N. Mechanical properties of cultured endothelial cells exposed to shear stress Frontiers of Medical and Biological Engineering : the International Journal of the Japan Society of Medical Electronics and Biological Engineering. 2: 171-175. PMID 2288884  0.356
1990 Sato M, Theret DP, Wheeler LT, Ohshima N, Nerem RM. Application of the micropipette technique to the measurement of cultured porcine aortic endothelial cell viscoelastic properties. Journal of Biomechanical Engineering. 112: 263-8. PMID 2214707 DOI: 10.1115/1.2891183  0.465
1990 Nerem RM, Girard PR. Hemodynamic influences on vascular endothelial biology Toxicologic Pathology. 18: 572-582. PMID 2091236 DOI: 10.1177/019262339001804A07  0.491
1990 Levesque MJ, Nerem RM, Sprague EA. Vascular endottielial cell proliferation in culture and the influence of flow Biomaterials. 11: 702-707. PMID 2090307 DOI: 10.1016/0142-9612(90)90031-K  0.447
1990 Nerem RM. Influence of flow on vascular cell function Journal of Japan Atherosclerosis Society. 18: 631-642.  0.305
1989 Schwartz CJ, Kelley JL, Nerem RM, Sprague EA, Rozek MM, Valente AJ, Edwards EH, Prasad AR, Kerbacher JJ, Logan SA. Pathophysiology of the atherogenic process. The American Journal of Cardiology. 64: 23G-30G. PMID 2679027 DOI: 10.1016/0002-9149(89)90952-1  0.366
1989 Levesque MJ, Nerem RM. The study of rheological effects on vascular endothelial cells in culture Biorheology. 26: 345-357. PMID 2605338 DOI: 10.3233/Bir-1989-26218  0.486
1989 Levesque MJ, Sprague EA, Schwartz CJ, Nerem RM. Influence of shear stress on cultured vascular endothelial cells: The stress response of an anchorage-dependent mammalian cell Biotechnology Progress. 5: 1-8. DOI: 10.1002/Btpr.5420050105  0.478
1988 Theret DP, Levesque MJ, Sato M, Nerem RM, Wheeler LT. The application of a homogeneous half-space model in the analysis of endothelial cell micropipette measurements Journal of Biomechanical Engineering. 110: 190-199. PMID 3172738 DOI: 10.1115/1.3108430  0.449
1988 Liepsch DW, Levesque M, Nerem RM, Moravec ST. Correlation of laser-Doppler-velocity measurements and endothelial cell shape in a stenosed dog aorta Advances in Experimental Medicine and Biology. 242: 43-50. PMID 2977525 DOI: 10.1007/978-1-4684-8935-4_6  0.429
1987 Sprague EA, Steinbach BL, Nerem RM, Schwartz CJ. Influence of a laminar steady-state fluid-imposed wall shear stress on the binding, internalization, and degradation of low-density lipoproteins by cultured arterial endothelium Circulation. 76: 648-656. PMID 3621525 DOI: 10.1161/01.Cir.76.3.648  0.349
1987 Sato M, Levesque MJ, Nerem RM. Micropipette aspiration of cultured bovine aortic endothelial cells exposed to shear stress Arteriosclerosis. 7: 276-286. PMID 3593075 DOI: 10.1161/01.Atv.7.3.276  0.449
1987 Sato M, Levesque MJ, Nerem RM. APPLICATION OF THE MICROPIPETTE TECHNIQUE TO THE MEASUREMENT OF THE MECHANICAL PROPERTIES OF CULTURED BOVINE AORTIC ENDOTHELIAL CELLS Journal of Biomechanical Engineering. 109: 27-34. PMID 3560876 DOI: 10.1115/1.3138638  0.448
1987 Levesque MJ, Nerem RM. SHEAR STRESS EFFECTS ON ENDOTHELIAL CELL MONOLAYER CULTURES . 47-50.  0.342
1986 Levesque MJ, Liepsch D, Moravec S, Nerem RM. Correlation of endothelial cell shape and wall shear stress in a stenosed dog aorta Arteriosclerosis. 6: 220-229. PMID 3954676 DOI: 10.1161/01.Atv.6.2.220  0.467
1986 Nerem RM, Levesque MJ, Sato M. RESPONSE OF LIVING VASCULAR CELLS TO MECHANICAL STRESS Proceedings of the U.S. National Congress of Applied Mechanics. 55-61.  0.408
1985 Levesque MJ, Nerem RM. The elongation and orientation of cultured endothelial cells in response to shear stress Journal of Biomechanical Engineering. 107: 341-347. PMID 4079361 DOI: 10.1115/1.3138567  0.487
1985 Nerem RM, Sato M, Levesque MJ. Elongation, orientation and effective shear modulus of cultured endothelial cells in response to shear Federation Proceedings. 44.  0.333
1985 Sato M, Levesque MJ, Nerem RM. APPLICATION OF THE MICROPIPETTE TECHNIQUE TO THE MEASUREMENT OF ENDOTHELIAL CELL MECHANICAL PROPERTIES American Society of Mechanical Engineers, Applied Mechanics Division, Amd. 68: 167-169.  0.385
1984 Nerem RM. Atherogenesis: Hemodynamics, vascular geometry, and the endothelium Biorheology. 21: 565-569. PMID 6487767  0.31
1983 Nerem RM, Levesque MJ. CHANGE OF ENDOTHELIAL CELL MORPHOLOGY WITH ARTERIAL GEOMETRY Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 192.  0.302
1983 Levesque MJ, Nerem RM. SHEAR AND PRESSURE EFFECTS ON CULTURED ENDOTHELIAL CELLS Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 165.  0.305
1981 Nerem RM, Levesque MJ, Cornhill JF. Vascular endothelial morphology as an indicator of the pattern of blood flow. Journal of Biomechanical Engineering. 103: 172-6. PMID 7278195 DOI: 10.1115/1.3138275  0.469
1980 Nerem RM, Cornhill JF. The role of fluid mechanics in atherogenesis. Journal of Biomechanical Engineering. 102: 181. PMID 19530798 DOI: 10.1115/1.3149571  0.304
1980 Nerem RM, Cornhill JF. Hemodynamics and atherogenesis. Atherosclerosis. 36: 151-7. PMID 7406946 DOI: 10.1016/0021-9150(80)90224-5  0.309
1980 Cornhill JF, Levesque MJ, Herderick EE, Nerem RM, Kilman JW, Vasko JS. Quantitative study of the rabbit aortic endothelium using vascular casts. Atherosclerosis. 35: 321-37. PMID 7362703 DOI: 10.1016/0021-9150(80)90130-6  0.317
1979 Levesque MJ, Cornhill JF, Nerem RM. Vascular casting. A new method for the study of the arterial endothelium. Atherosclerosis. 34: 457-67. PMID 518748 DOI: 10.1016/0021-9150(79)90070-4  0.335
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