| Year |
Citation |
Score |
| 2020 |
Nath A, Oak A, Chen KY, Li I, Splichal RC, Portis J, Foster S, Walton SP, Chan C. Palmitate-induced IRE1-XBP1-ZEB signaling represses desmoplakin expression and promotes cancer cell migration. Molecular Cancer Research : McR. PMID 33106375 DOI: 10.1158/1541-7786.MCR-19-0480 |
0.766 |
|
| 2020 |
Splichal RC, Gredell JA, Vogel EB, Malefyt A, Comiskey G, Smith MR, Chan C, Walton SP. Modulating Polymer-siRNA Binding Does Not Promote Polyplex-Mediated Silencing. Nucleic Acid Therapeutics. PMID 32749923 DOI: 10.1089/Nat.2020.0857 |
0.753 |
|
| 2019 |
Vocelle D, Chan C, Walton SP. Endocytosis Controls Small Interfering RNA Efficiency: Implications for Small Interfering RNA Delivery Vehicle Design and Cell-Specific Targeting. Nucleic Acid Therapeutics. PMID 31718426 DOI: 10.1089/Nat.2019.0804 |
0.317 |
|
| 2019 |
Dalgic E, Konu O, Oz ZS, Chan C. Lower connectivity of tumor coexpression networks is not specific to cancer. In Silico Biology. 13: 41-53. PMID 31156157 DOI: 10.3233/Isb-190472 |
0.308 |
|
| 2019 |
Cho H, Stanzione F, Oak A, Kim GH, Yerneni S, Qi L, Sum AK, Chan C. Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation. Cell Reports. 27: 307-320.e5. PMID 30943411 DOI: 10.1016/J.Celrep.2019.03.017 |
0.503 |
|
| 2016 |
Vocelle D, Chesniak OM, Malefyt AP, Comiskey G, Adu-Berchie K, Smith MR, Chan C, Walton SP. Dextran functionalization enhances nanoparticle-mediated siRNA delivery and silencing. Technology. 4. PMID 27774502 DOI: 10.1142/S2339547816400100 |
0.766 |
|
| 2016 |
Bilgin B, Nath A, Chan C, Walton SP. Characterization of transcription factor response kinetics in parallel. Bmc Biotechnology. 16: 62. PMID 27557669 DOI: 10.1186/S12896-016-0293-6 |
0.681 |
|
| 2016 |
Wang T, Srivastava S, Hartman M, Buhari SA, Chan CW, Iau P, Khin LW, Wong A, Tan SH, Goh BC, Lee SC. High expression of intratumoral stromal proteins is associated with chemotherapy resistance in breast cancer. Oncotarget. PMID 27487140 DOI: 10.18632/oncotarget.10894 |
0.496 |
|
| 2016 |
Nath A, Chan C. Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers. Scientific Reports. 6: 18669. PMID 26725848 DOI: 10.1038/Srep18669 |
0.691 |
|
| 2016 |
Nath A, Chan C. Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers Scientific Reports. 6. DOI: 10.1038/srep18669 |
0.652 |
|
| 2015 |
Nath A, Li I, Roberts LR, Chan C. Elevated free fatty acid uptake via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma. Scientific Reports. 5: 14752. PMID 26424075 DOI: 10.1038/Srep14752 |
0.762 |
|
| 2015 |
Zhang L, Bell BA, Yu M, Chan CC, Peachey NS, Fung J, Zhang X, Caspi RR, Lin F. Complement anaphylatoxin receptors C3aR and C5aR are required in the pathogenesis of experimental autoimmune uveitis. Journal of Leukocyte Biology. PMID 26394814 DOI: 10.1189/Jlb.3A0415-157R |
0.42 |
|
| 2015 |
Kowalsky CA, Faber MS, Nath A, Dann HE, Kelly VW, Liu L, Shanker P, Wagner EK, Maynard JA, Chan C, Whitehead TA. Rapid Fine Conformational Epitope Mapping Using Comprehensive Mutagenesis and Deep Sequencing. The Journal of Biological Chemistry. PMID 26296891 DOI: 10.1074/Jbc.M115.676635 |
0.649 |
|
| 2015 |
Chan CK, Tüysüz H, Braun A, Ranjan C, La Mantia F, Miller BK, Zhang L, Crozier PA, Haber JA, Gregoire JM, Park HS, Batchellor AS, Trotochaud L, Boettcher SW. Advanced and In Situ Analytical Methods for Solar Fuel Materials. Topics in Current Chemistry. PMID 26267386 DOI: 10.1007/128_2015_650 |
0.405 |
|
| 2015 |
Fok EW, Poon WL, Tse KS, Lau HY, Chan CH, Pan NY, Cho HY, Yeung TW, Wong YC, Leung KW, Khoo JL, Tang KW. Angiographic factors associated with haemorrhagic presentation of brain arteriovenous malformation in a Chinese paediatric population. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy of Medicine. PMID 26234688 DOI: 10.12809/hkmj144339 |
0.409 |
|
| 2015 |
Zhao H, Chiaro CR, Zhang L, Smith PB, Chan CY, Pedley AM, Pugh RJ, French JB, Patterson AD, Benkovic SJ. Quantitative analysis of purine nucleotides indicates that purinosomes increase de novo purine biosynthesis. The Journal of Biological Chemistry. 290: 6705-13. PMID 25605736 DOI: 10.1074/Jbc.M114.628701 |
0.468 |
|
| 2015 |
Nath A, Chan C. Abstract A1-58: Revisiting cancer energetics: Establishing a link between altered fatty-acid metabolism and metastasis Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A1-58 |
0.693 |
|
| 2015 |
Nath A, Li I, Chan C. Abstract 5157: Elevated uptake of free fatty acids via CD36 promotes epithelial-mesenchymal transition in hepatocellular carcinoma Cancer Research. 75: 5157-5157. DOI: 10.1158/1538-7445.Am2015-5157 |
0.767 |
|
| 2014 |
Zhang L, Liu L, Thompson R, Chan C. CREB modulates calcium signaling in cAMP-induced bone marrow stromal cells (BMSCs). Cell Calcium. 56: 257-68. PMID 25154887 DOI: 10.1016/J.Ceca.2014.07.013 |
0.487 |
|
| 2014 |
Fang L, Cho HJ, Chan C, Feig M. Binding site multiplicity with fatty acid ligands: implications for the regulation of PKR kinase autophosphorylation with palmitate. Proteins. 82: 2429-42. PMID 24862841 DOI: 10.1002/Prot.24607 |
0.52 |
|
| 2014 |
Lynam D, Peterson C, Maloney R, Shahriari D, Garrison A, Saleh S, Mehrotra S, Chan C, Sakamoto J. Augmenting protein release from layer-by-layer functionalized agarose hydrogels. Carbohydrate Polymers. 103: 377-84. PMID 24528743 DOI: 10.1016/J.Carbpol.2013.12.069 |
0.485 |
|
| 2014 |
Cao Z, Zhang L, Chan CY, Ong HC. Interplay between absorption and radiative decay rates of surface plasmon polaritons for field enhancement in periodic arrays. Optics Letters. 39: 501-4. PMID 24487850 DOI: 10.1364/Ol.39.000501 |
0.401 |
|
| 2014 |
Malefyt AP, Wu M, Vocelle DB, Kappes SJ, Lindeman SD, Chan C, Walton SP. Improved asymmetry prediction for short interfering RNAs. The Febs Journal. 281: 320-30. PMID 24393396 DOI: 10.1111/Febs.12599 |
0.75 |
|
| 2013 |
Patil SP, Tran N, Geekiyanage H, Liu L, Chan C. Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons. Neuroscience Letters. 554: 121-5. PMID 24035895 DOI: 10.1016/J.Neulet.2013.09.008 |
0.762 |
|
| 2013 |
Angart P, Vocelle D, Chan C, Walton SP. Design of siRNA Therapeutics from the Molecular Scale. Pharmaceuticals (Basel, Switzerland). 6: 440-68. PMID 23976875 DOI: 10.3390/Ph6040440 |
0.3 |
|
| 2013 |
Liu L, Martin R, Kohler G, Chan C. Palmitate induces transcriptional regulation of BACE1 and presenilin by STAT3 in neurons mediated by astrocytes. Experimental Neurology. 248: 482-90. PMID 23968646 DOI: 10.1016/j.expneurol.2013.08.004 |
0.31 |
|
| 2013 |
Chan CK, Lindau P, Jiang W, Chen JY, Zhang LF, Chen CC, Seita J, Sahoo D, Kim JB, Lee A, Park S, Nag D, Gong Y, Kulkarni S, Luppen CA, et al. Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12643-8. PMID 23858471 DOI: 10.1073/Pnas.1310212110 |
0.434 |
|
| 2013 |
Pan X, Whitten DA, Wu M, Chan C, Wilkerson CG, Pestka JJ. Early phosphoproteomic changes in the mouse spleen during deoxynivalenol-induced ribotoxic stress. Toxicological Sciences : An Official Journal of the Society of Toxicology. 135: 129-43. PMID 23811945 DOI: 10.1093/Toxsci/Kft145 |
0.313 |
|
| 2013 |
Wu M, Liu L, Hijazi H, Chan C. A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics (Oxford, England). 29: 1541-52. PMID 23610368 DOI: 10.1093/Bioinformatics/Btt186 |
0.312 |
|
| 2013 |
Geekiyanage H, Upadhye A, Chan C. Inhibition of serine palmitoyltransferase reduces Aβ and tau hyperphosphorylation in a murine model: a safe therapeutic strategy for Alzheimer's disease. Neurobiology of Aging. 34: 2037-51. PMID 23528227 DOI: 10.1016/J.Neurobiolaging.2013.02.001 |
0.76 |
|
| 2013 |
Pan X, Whitten DA, Wu M, Chan C, Wilkerson CG, Pestka JJ. Global protein phosphorylation dynamics during deoxynivalenol-induced ribotoxic stress response in the macrophage. Toxicology and Applied Pharmacology. 268: 201-11. PMID 23352502 DOI: 10.1016/J.Taap.2013.01.007 |
0.333 |
|
| 2013 |
Cho H, Wu M, Zhang L, Thompson R, Nath A, Chan C. Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells. Bmc Systems Biology. 7: 9. PMID 23339444 DOI: 10.1186/1752-0509-7-9 |
0.772 |
|
| 2013 |
Nath A, Chan C. Abstract C29: Free fatty acid induced epithelial to mesenchymal transition (EMT) in hepatocellular carcinoma cells Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C29 |
0.688 |
|
| 2013 |
Cho H, Stanzione F, LaMarca R, Sum AK, Chan C. Computational and Experimental Analyses of the Transmembrane Domain Dimerization of IRE1α Protein Biophysical Journal. 104: 406a. DOI: 10.1016/J.Bpj.2012.11.2265 |
0.503 |
|
| 2012 |
Hijazi H, Wu M, Nath A, Chan C. Ensemble Classification of Cancer Types and Biomarker Identification. Drug Development Research. 73: 414-419. PMID 25221378 DOI: 10.1002/Ddr.21032 |
0.66 |
|
| 2012 |
Malefyt AP, Walton SP, Chan C. ENDOCYTOSIS PATHWAYS FOR NUCLEIC ACID THERAPEUTICS. Nano Life. 2: 1241005. PMID 23956796 DOI: 10.1142/S179398441241005X |
0.766 |
|
| 2012 |
Cho H, Lamarca R, Chan C. Oligomerization of the transmembrane domain of IRE1α in SDS micelles. Biochemical and Biophysical Research Communications. 427: 764-7. PMID 23041190 DOI: 10.1016/J.Bbrc.2012.09.135 |
0.491 |
|
| 2012 |
Cho H, Wu M, Bilgin B, Walton SP, Chan C. Latest developments in experimental and computational approaches to characterize protein-lipid interactions. Proteomics. 12: 3273-85. PMID 22997137 DOI: 10.1002/Pmic.201200255 |
0.507 |
|
| 2012 |
Yang X, Chan C, Lam D, Schipper D, Stanley JM, Chen X, Jones RA, Holliday BJ, Wong WK, Chen S, Chen Q. Anion-dependent construction of two hexanuclear 3d-4f complexes with a flexible Schiff base ligand. Dalton Transactions (Cambridge, England : 2003). 41: 11449-53. PMID 22892983 DOI: 10.1039/C2Dt31268A |
0.394 |
|
| 2012 |
Zhang L, Chan CY, Li J, Ong HC. Rational design of high performance surface plasmon resonance sensors based on two-dimensional metallic hole arrays. Optics Express. 20: 12610-21. PMID 22714248 DOI: 10.1364/Oe.20.012610 |
0.411 |
|
| 2012 |
Wu J, Zhang X, Zhang L, Wu CY, Rezaeian AH, Chan CH, Li JM, Wang J, Gao Y, Han F, Jeong YS, Yuan X, Khanna KK, Jin J, Zeng YX, et al. Skp2 E3 ligase integrates ATM activation and homologous recombination repair by ubiquitinating NBS1. Molecular Cell. 46: 351-61. PMID 22464731 DOI: 10.1016/J.Molcel.2012.02.018 |
0.418 |
|
| 2012 |
Geekiyanage H, Jicha GA, Nelson PT, Chan C. Blood serum miRNA: non-invasive biomarkers for Alzheimer's disease. Experimental Neurology. 235: 491-6. PMID 22155483 DOI: 10.1016/J.Expneurol.2011.11.026 |
0.75 |
|
| 2012 |
Wu M, Chan C. Learning transcriptional regulation on a genome scale: a theoretical analysis based on gene expression data. Briefings in Bioinformatics. 13: 150-61. PMID 21622543 DOI: 10.1093/Bib/Bbr029 |
0.306 |
|
| 2012 |
Mehrotra S, Lynam D, Liu C, Shahriari D, Lee I, Tuszynski M, Sakamoto J, Chan C. Time controlled release of arabinofuranosylcytosine (Ara-C) from agarose hydrogels using layer-by-layer assembly: an in vitro study. Journal of Biomaterials Science. Polymer Edition. 23: 439-63. PMID 21294967 DOI: 10.1163/092050610X552221 |
0.486 |
|
| 2012 |
Geekiyanage H, Chan C. P3-044: SPT, miR-137 and miR-181c: Therapeutic targets and noninvasive biomarkers Alzheimer's & Dementia. 8: P470-P471. DOI: 10.1016/J.Jalz.2012.05.1262 |
0.738 |
|
| 2012 |
Cho H, Fang L, Feig M, Chan C. Molecular Mechanism of Activation of IRE1α Cytosolic Domain by Palmitate Biophysical Journal. 102: 627a-628a. DOI: 10.1016/J.Bpj.2011.11.3417 |
0.526 |
|
| 2011 |
Wang X, Nath A, Yang X, Portis A, Walton SP, Chan C. Synergy analysis reveals association between insulin signaling and desmoplakin expression in palmitate treated HepG2 cells. Plos One. 6: e28138. PMID 22132232 DOI: 10.1371/Journal.Pone.0028138 |
0.742 |
|
| 2011 |
Wu M, Liu L, Chan C. Identification of novel targets for breast cancer by exploring gene switches on a genome scale. Bmc Genomics. 12: 547. PMID 22053771 DOI: 10.1186/1471-2164-12-547 |
0.316 |
|
| 2011 |
Powell DA, Black WC, Bleasby K, Chan CC, Deschenes D, Gagnon M, Gordon R, Guay J, Guiral S, Hafey MJ, Huang Z, Isabel E, Leblanc Y, Styhler A, Xu LJ, et al. Nicotinic acids: liver-targeted SCD inhibitors with preclinical anti-diabetic efficacy. Bioorganic & Medicinal Chemistry Letters. 21: 7281-6. PMID 22047692 DOI: 10.1016/j.bmcl.2011.10.040 |
0.452 |
|
| 2011 |
Geekiyanage H, Chan C. MicroRNA-137/181c regulates serine palmitoyltransferase and in turn amyloid β, novel targets in sporadic Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14820-30. PMID 21994399 DOI: 10.1523/Jneurosci.3883-11.2011 |
0.76 |
|
| 2011 |
Yang X, Lam D, Chan C, Stanley JM, Jones RA, Holliday BJ, Wong WK. Construction of 1-D 4f and 3d-4f coordination polymers with flexible Schiff base ligands. Dalton Transactions (Cambridge, England : 2003). 40: 9795-801. PMID 21874186 DOI: 10.1039/C1Dt11036E |
0.393 |
|
| 2011 |
Mehrotra S, Lee I, Liu C, Chan C. POLYELECTROLYTE MULTILAYER STAMPING IN AQUEOUS PHASE AND NON-CONTACT MODE. Industrial & Engineering Chemistry Research. 50: 8851-8858. PMID 21860540 DOI: 10.1021/Ie102011M |
0.478 |
|
| 2011 |
Oballa RM, Belair L, Black WC, Bleasby K, Chan CC, Desroches C, Du X, Gordon R, Guay J, Guiral S, Hafey MJ, Hamelin E, Huang Z, Kennedy B, Lachance N, et al. Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia. Journal of Medicinal Chemistry. 54: 5082-96. PMID 21661758 DOI: 10.1021/jm200319u |
0.444 |
|
| 2011 |
Landry F, Chan CC, Huang Z, Leclair G, Li CS, Oballa R, Zhang L, Bateman K. Plasma-based approach to measure target engagement for liver-targeting stearoyl-CoA desaturase 1 inhibitors. Journal of Lipid Research. 52: 1494-9. PMID 21642745 DOI: 10.1194/jlr.M013177 |
0.469 |
|
| 2011 |
Cho H, Mukherjee S, Palasuberniam P, Pillow L, Bilgin B, Nezich C, Walton SP, Feig M, Chan C. Molecular mechanism by which palmitate inhibits PKR autophosphorylation. Biochemistry. 50: 1110-9. PMID 21192654 DOI: 10.1021/Bi101923R |
0.528 |
|
| 2011 |
Isabel E, Powell DA, Black WC, Chan CC, Crane S, Gordon R, Guay J, Guiral S, Huang Z, Robichaud J, Skorey K, Tawa P, Xu L, Zhang L, Oballa R. Biological activity and preclinical efficacy of azetidinyl pyridazines as potent systemically-distributed stearoyl-CoA desaturase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 479-83. PMID 21074991 DOI: 10.1016/j.bmcl.2010.10.107 |
0.422 |
|
| 2011 |
Zhang L, Seitz LC, Abramczyk AM, Liu L, Chan C. cAMP initiates early phase neuron-like morphology changes and late phase neural differentiation in mesenchymal stem cells. Cellular and Molecular Life Sciences : Cmls. 68: 863-76. PMID 20725762 DOI: 10.1007/S00018-010-0497-1 |
0.497 |
|
| 2010 |
Chan C, Yang X, Jones RA, Holliday BJ, Stanley JM. {μ-6,6'-Dimeth-oxy-2,2'-[butane-1,4-diylbis(nitrilo-methyl-idyne)]diphenolato-1:2κO,O,O,O:O,N,N',O}tris-(nitrato-1κO,O')copper(II)gadolinium(III). Acta Crystallographica. Section E, Structure Reports Online. 66: m576-7. PMID 21579057 DOI: 10.1107/S1600536810014716 |
0.384 |
|
| 2010 |
Yang X, Nath A, Opperman MJ, Chan C. The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cells. Molecular Biology of the Cell. 21: 3449-58. PMID 20685959 DOI: 10.1091/Mbc.E10-06-0481 |
0.728 |
|
| 2010 |
Mehrotra S, Hunley SC, Pawelec KM, Zhang L, Lee I, Baek S, Chan C. Cell adhesive behavior on thin polyelectrolyte multilayers: cells attempt to achieve homeostasis of its adhesion energy. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 12794-802. PMID 20604583 DOI: 10.1021/La101689Z |
0.607 |
|
| 2010 |
Dalkic E, Wang X, Wright N, Chan C. Cancer-drug associations: a complex system. Plos One. 5: e10031. PMID 20368808 DOI: 10.1371/Journal.Pone.0010031 |
0.755 |
|
| 2010 |
Zhang L, Chan C. Isolation and enrichment of rat mesenchymal stem cells (MSCs) and separation of single-colony derived MSCs. Journal of Visualized Experiments : Jove. PMID 20308982 DOI: 10.3791/1852 |
0.493 |
|
| 2010 |
Mehrotra S, Lynam D, Maloney R, Pawelec KM, Tuszynski MH, Lee I, Chan C, Sakamoto J. Time Controlled Protein Release from Layer-by-Layer Assembled Multilayer Functionalized Agarose Hydrogels. Advanced Functional Materials. 20: 247-258. PMID 20200599 DOI: 10.1002/Adfm.200901172 |
0.496 |
|
| 2010 |
Ramtohul YK, Black C, Chan CC, Crane S, Guay J, Guiral S, Huang Z, Oballa R, Xu LJ, Zhang L, Li CS. SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 1593-7. PMID 20137926 DOI: 10.1016/j.bmcl.2010.01.083 |
0.426 |
|
| 2010 |
Zhang LS, Wong KH, Yip HY, Hu C, Yu JC, Chan CY, Wong PK. Effective photocatalytic disinfection of E. coli K-12 using AgBr-Ag-Bi2WO6 nanojunction system irradiated by visible light: the role of diffusing hydroxyl radicals. Environmental Science & Technology. 44: 1392-8. PMID 20085257 DOI: 10.1021/Es903087W |
0.411 |
|
| 2010 |
Zhang L, Seitz LC, Abramczyk AM, Chan C. Synergistic effect of cAMP and palmitate in promoting altered mitochondrial function and cell death in HepG2 cells. Experimental Cell Research. 316: 716-27. PMID 20026039 DOI: 10.1016/J.Yexcr.2009.12.008 |
0.492 |
|
| 2010 |
Chan C, Geekiyanage H. P2-243: The role of micro-RNAs in the progression of Alzheimer's disease mediated by serine palmitoyltransferase Alzheimer's & Dementia. 6: S385-S385. DOI: 10.1016/J.Jalz.2010.05.1292 |
0.75 |
|
| 2009 |
Williams P, Chan CC, Buggage R, Srivastava S, Callanan D. Pituitary adenoma presenting as bilateral bullous exudative retinal detachments: a clinicopathologic report. Retinal Cases & Brief Reports. 3: 230-2. PMID 25391084 DOI: 10.1097/ICB.0b013e31815f3cac |
0.446 |
|
| 2009 |
Dalkic E, Nash DE, Fassia MK, Chan C. Integrative analysis of cancer pathway progression and coherence. Proteomics. Clinical Applications. 3: 473-85. PMID 21136972 DOI: 10.1002/Prca.200800074 |
0.765 |
|
| 2009 |
Wu M, Yang X, Chan C. A dynamic analysis of IRS-PKR signaling in liver cells: a discrete modeling approach. Plos One. 4: e8040. PMID 19956598 DOI: 10.1371/Journal.Pone.0008040 |
0.522 |
|
| 2009 |
Zhang LS, Wong KH, Zhang DQ, Hu C, Yu JC, Chan CY, Wong PK. Zn:In(OH)ySz solid solution nanoplates: synthesis, characterization, and photocatalytic mechanism. Environmental Science & Technology. 43: 7883-8. PMID 19921909 DOI: 10.1021/Es902013D |
0.409 |
|
| 2009 |
Yang X, Zhou Y, Jin R, Chan C. Reconstruct modular phenotype-specific gene networks by knowledge-driven matrix factorization. Bioinformatics (Oxford, England). 25: 2236-43. PMID 19542155 DOI: 10.1093/Bioinformatics/Btp376 |
0.522 |
|
| 2009 |
Leekumjorn S, Cho HJ, Wu Y, Wright NT, Sum AK, Chan C. The role of fatty acid unsaturation in minimizing biophysical changes on the structure and local effects of bilayer membranes. Biochimica Et Biophysica Acta. 1788: 1508-16. PMID 19371719 DOI: 10.1016/J.Bbamem.2009.04.002 |
0.508 |
|
| 2009 |
Li Z, Chan C. Systems biology for identifying liver toxicity pathways. Bmc Proceedings. 3: S2. PMID 19278558 DOI: 10.1186/1753-6561-3-S2-S2 |
0.303 |
|
| 2009 |
Yang X, Chan C. Repression of PKR mediates palmitate-induced apoptosis in HepG2 cells through regulation of Bcl-2. Cell Research. 19: 469-86. PMID 19259124 DOI: 10.1038/Cr.2009.25 |
0.536 |
|
| 2009 |
Mehrotra S, Lee I, Chan C. Multilayer mediated forward and patterned siRNA transfection using linear-PEI at extended N/P ratios. Acta Biomaterialia. 5: 1474-88. PMID 19217360 DOI: 10.1016/J.Actbio.2009.01.004 |
0.499 |
|
| 2009 |
Li Z, He ML, Yao H, Dong QM, Chen YC, Chan CY, Zheng BJ, Yuen KY, Peng Y, Sun Q, Yang X, Lin MC, Sung JJ, Kung HF. Inhibition of HBV replication and gene expression in vitro and in vivo with a single AAV vector delivering two shRNA molecules. Bmb Reports. 42: 59-64. PMID 19192395 DOI: 10.5483/Bmbrep.2009.42.1.059 |
0.449 |
|
| 2009 |
Shalev I, Wong KM, Foerster K, Zhu Y, Chan C, Maknojia A, Zhang J, Ma XZ, Yang XC, Gao JF, Liu H, Selzner N, Clark DA, Adeyi O, Phillips MJ, et al. The novel CD4+CD25+ regulatory T cell effector molecule fibrinogen-like protein 2 contributes to the outcome of murine fulminant viral hepatitis. Hepatology (Baltimore, Md.). 49: 387-97. PMID 19085958 DOI: 10.1002/Hep.22684 |
0.439 |
|
| 2008 |
Kidambi S, Lee I, Chan C. Primary Neuron/Astrocyte Co-Culture on Polyelectrolyte Multilayer Films: A Template for Studying Astrocyte-Mediated Oxidative Stress in Neurons. Advanced Functional Materials. 18: 294-301. PMID 25400537 DOI: 10.1002/Adfm.200601237 |
0.573 |
|
| 2008 |
Srivastava S, Zhang L, Jin R, Chan C. A novel method incorporating gene ontology information for unsupervised clustering and feature selection. Plos One. 3: e3860. PMID 19052637 DOI: 10.1371/Journal.Pone.0003860 |
0.656 |
|
| 2008 |
Wang X, Dalkic E, Wu M, Chan C. Gene module level analysis: identification to networks and dynamics. Current Opinion in Biotechnology. 19: 482-91. PMID 18725293 DOI: 10.1016/J.Copbio.2008.07.011 |
0.757 |
|
| 2008 |
Li Z, Srivastava S, Findlan R, Chan C. Using dynamic gene module map analysis to identify targets that modulate free fatty acid induced cytotoxicity. Biotechnology Progress. 24: 29-37. PMID 18052188 DOI: 10.1021/Bp070120B |
0.577 |
|
| 2008 |
Kidambi S, Chan C, Lee I. Tunable resistive m-dPEG acid patterns on polyelectrolyte multilayers at physiological conditions: template for directed deposition of biomacromolecules. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 224-30. PMID 18052083 DOI: 10.1021/La702925R |
0.583 |
|
| 2008 |
Srivastava S, Chan C. Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line. Biotechnology and Bioengineering. 99: 399-410. PMID 17615559 DOI: 10.1002/Bit.21568 |
0.568 |
|
| 2007 |
Srivastava S, Li Z, Yang X, Yedwabnick M, Shaw S, Chan C. Identification of genes that regulate multiple cellular processes/responses in the context of lipotoxicity to hepatoma cells. Bmc Genomics. 8: 364. PMID 17925029 DOI: 10.1186/1471-2164-8-364 |
0.679 |
|
| 2007 |
Zhang X, Kong B, Tsui OK, Yang X, Mi Y, Chan CM, Xu B. Effect of pattern topology on the self-cleaning properties of textured surfaces. The Journal of Chemical Physics. 127: 014703. PMID 17627360 DOI: 10.1063/1.2748383 |
0.403 |
|
| 2007 |
Li Z, Srivastava S, Mittal S, Yang X, Sheng L, Chan C. A Three Stage Integrative Pathway Search (TIPS) framework to identify toxicity relevant genes and pathways. Bmc Bioinformatics. 8: 202. PMID 17570844 DOI: 10.1186/1471-2105-8-202 |
0.673 |
|
| 2007 |
Buggage RR, Levy-Clarke G, Sen HN, Ursea R, Srivastava SK, Suhler EB, Altemare C, Velez G, Ragheb J, Chan CC, Nussenblatt RB, Bamji AT, Sran P, Waldmann T, Thompson DJ. A double-masked, randomized study to investigate the safety and efficacy of daclizumab to treat the ocular complications related to Behçet's disease. Ocular Immunology and Inflammation. 15: 63-70. PMID 17558830 DOI: 10.1080/09273940701299370 |
0.455 |
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| 2007 |
Kidambi S, Udpa N, Schroeder SA, Findlan R, Lee I, Chan C. Cell adhesion on polyelectrolyte multilayer coated polydimethylsiloxane surfaces with varying topographies. Tissue Engineering. 13: 2105-17. PMID 17518734 DOI: 10.1089/Ten.2006.0151 |
0.587 |
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| 2007 |
Li Z, Srivastava S, Yang X, Mittal S, Norton P, Resau J, Haab B, Chan C. A hierarchical approach employing metabolic and gene expression profiles to identify the pathways that confer cytotoxicity in HepG2 cells. Bmc Systems Biology. 1: 21. PMID 17498300 DOI: 10.1186/1752-0509-1-21 |
0.671 |
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| 2007 |
Kidambi S, Sheng L, Yarmush ML, Toner M, Lee I, Chan C. Patterned co-culture of primary hepatocytes and fibroblasts using polyelectrolyte multilayer templates. Macromolecular Bioscience. 7: 344-53. PMID 17370273 DOI: 10.1002/Mabi.200600205 |
0.641 |
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| 2007 |
Srivastava S, Chan C. Hydrogen peroxide and hydroxyl radicals mediate palmitate-induced cytotoxicity to hepatoma cells: relation to mitochondrial permeability transition. Free Radical Research. 41: 38-49. PMID 17164177 DOI: 10.1080/10715760600943900 |
0.529 |
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| 2006 |
Jin R, Si L, Srivastava S, Li Z, Chan C. A knowledge driven regression model for gene expression and microarray analysis. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 5326-9. PMID 17945892 DOI: 10.1109/IEMBS.2006.260347 |
0.487 |
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| 2006 |
Jiao B, Huang X, Chan CB, Zhang L, Wang D, Cheng CH. The co-existence of two growth hormone receptors in teleost fish and their differential signal transduction, tissue distribution and hormonal regulation of expression in seabream. Journal of Molecular Endocrinology. 36: 23-40. PMID 16461924 DOI: 10.1677/Jme.1.01945 |
0.448 |
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| 2006 |
Huang Z, Liu S, Zhang L, Salem M, Greig GM, Chan CC, Natsumeda Y, Noguchi K. Preferential inhibition of human phosphodiesterase 4 by ibudilast. Life Sciences. 78: 2663-8. PMID 16313925 DOI: 10.1016/j.lfs.2005.10.026 |
0.421 |
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| 2005 |
Srivastava SK, Martin DF, Mellow SD, Parks DJ, Dastgheib K, Chan CC. Pathological findings in eyes with the ganciclovir implant. Ophthalmology. 112: 780-6. PMID 15878057 DOI: 10.1016/j.ophtha.2004.11.042 |
0.434 |
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| 2004 |
Li Z, Yarmush ML, Chan C. Insulin concentration during preconditioning mediates the regulation of urea synthesis during exposure to amino acid-supplemented plasma Tissue Engineering. 10: 1737-1746. PMID 15684682 DOI: 10.1089/Ten.2004.10.1737 |
0.456 |
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| 2004 |
Kidambi S, Lee I, Chan C. Controlling primary hepatocyte adhesion and spreading on protein-free polyelectrolyte multilayer films. Journal of the American Chemical Society. 126: 16286-7. PMID 15600306 DOI: 10.1021/Ja046188U |
0.582 |
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| 2004 |
Chan C, Berthiaume F, Nath BD, Tilles AW, Toner M, Yarmush ML. Hepatic tissue engineering for adjunct and temporary liver support: critical technologies. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 10: 1331-42. PMID 15497161 DOI: 10.1002/Lt.20229 |
0.416 |
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| 2004 |
Li Z, Chan C. Integrating gene expression and metabolic profiles. Journal of Biological Chemistry. 279: 27124-27137. PMID 15107427 DOI: 10.1074/Jbc.M403494200 |
0.32 |
|
| 2004 |
Kidambi S, Chan C, Lee I. Selective depositions on polyelectrolyte multilayers: self-assembled monolayers of m-dPEG acid as molecular template. Journal of the American Chemical Society. 126: 4697-703. PMID 15070388 DOI: 10.1021/Ja039359O |
0.564 |
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| 2003 |
Nussenblatt RB, Thompson DJ, Li Z, Chan CC, Peterson JS, Robinson RR, Shames RS, Nagarajan S, Tang MT, Mailman M, Velez G, Roy C, Levy-Clarke GA, Suhler EB, Djalilian A, et al. Humanized anti-interleukin-2 (IL-2) receptor alpha therapy: long-term results in uveitis patients and preliminary safety and activity data for establishing parameters for subcutaneous administration. Journal of Autoimmunity. 21: 283-93. PMID 14599854 DOI: 10.1016/S0896-8411(03)00113-6 |
0.449 |
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| 2003 |
Chan C, Berthiaume F, Lee K, Yarmush ML. Metabolic flux analysis of hepatocyte function in hormone- and amino acid-supplemented plasma. Metabolic Engineering. 5: 1-15. PMID 12749840 DOI: 10.1016/S1096-7176(02)00011-3 |
0.464 |
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| 2003 |
Chan CW, Kay LS, Khadaroo RG, Chan MW, Lakatoo S, Young KJ, Zhang L, Gorczynski RM, Cattral M, Rotstein O, Levy GA. Soluble fibrinogen-like protein 2/fibroleukin exhibits immunosuppressive properties: suppressing T cell proliferation and inhibiting maturation of bone marrow-derived dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 4036-44. PMID 12682232 DOI: 10.4049/Jimmunol.170.8.4036 |
0.445 |
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| 2003 |
Chan C, Hwang D, Stephanopoulos GN, Yarmush ML, Stephanopoulos G. Application of multivariate analysis to optimize function of cultured hepatocytes. Biotechnology Progress. 19: 580-98. PMID 12675604 DOI: 10.1021/Bp025660H |
0.454 |
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| 2003 |
Chan C, Berthiaume F, Lee K, Yarmush ML. Metabolic flux analysis of cultured hepatocytes exposed to plasma. Biotechnology and Bioengineering. 81: 33-49. PMID 12432579 DOI: 10.1002/Bit.10453 |
0.458 |
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| 2002 |
Mehta S, Yang XM, Chan CS, Dobson MJ, Jayaram M, Velmurugan S. The 2 micron plasmid purloins the yeast cohesin complex: a mechanism for coupling plasmid partitioning and chromosome segregation? The Journal of Cell Biology. 158: 625-37. PMID 12177044 DOI: 10.1083/Jcb.200204136 |
0.401 |
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| 2002 |
Chan C, Berthiaume F, Washizu J, Toner M, Yarmush ML. Metabolic pre-conditioning of cultured cells in physiological levels of insulin: generating resistance to the lipid-accumulating effects of plasma in hepatocytes. Biotechnology and Bioengineering. 78: 753-60. PMID 12001167 DOI: 10.1002/Bit.10275 |
0.449 |
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| 2002 |
Chan C, Berthiaume F, Washizu J, Toner M, Yarmush ML. Metabolic pre-conditioning of cultured cells in physiological levels of insulin: Generating resistance to the lipid-accumulating effects of plasma in hepatocytes Biotechnology and Bioengineering. 79: 364-364. DOI: 10.1002/Bit.10420 |
0.44 |
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| 2001 |
Tang ZK, Zhang L, Wang N, Zhang XX, Wen GH, Li GD, Wang JN, Chan CT, Sheng P. Superconductivity in 4 angstrom single-walled carbon nanotubes. Science (New York, N.Y.). 292: 2462-5. PMID 11431560 DOI: 10.1126/Science.1060470 |
0.4 |
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| 2001 |
Xin B, He Z, Yang X, Chan CP, Ng MH, Cao L. TRADD domain of Epstein-Barr virus transforming protein LMP1 is essential for inducing immortalization and suppressing senescence of primary rodent fibroblasts. Journal of Virology. 75: 3010-5. PMID 11222727 DOI: 10.1128/JVI.75.6.3010-3015.2001 |
0.451 |
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| 2000 |
Washizu J, Chan C, Berthiaume F, Tompkins RG, Toner M, Yarmush ML. Amino acid supplementation improves cell-specific functions of the rat hepatocytes exposed to human plasma. Tissue Engineering. 6: 497-504. PMID 11074936 DOI: 10.1089/107632700750022143 |
0.435 |
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| 2000 |
Washizu J, Berthiaume F, Chan C, Tompkins RG, Toner M, Yarmush ML. Optimization of rat hepatocyte culture in citrated human plasma. The Journal of Surgical Research. 93: 237-46. PMID 11027466 DOI: 10.1006/Jsre.2000.5986 |
0.419 |
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| 2000 |
Velmurugan S, Yang XM, Chan CS, Dobson M, Jayaram M. Partitioning of the 2-microm circle plasmid of Saccharomyces cerevisiae. Functional coordination with chromosome segregation and plasmid-encoded rep protein distribution. The Journal of Cell Biology. 149: 553-66. PMID 10791970 DOI: 10.1083/Jcb.149.3.553 |
0.425 |
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| 2000 |
He Z, Xin B, Yang X, Chan C, Cao L. Nuclear factor-kappaB activation is involved in LMP1-mediated transformation and tumorigenesis of rat-1 fibroblasts. Cancer Research. 60: 1845-8. PMID 10766170 |
0.449 |
|
| 1998 |
Heng L, Chan C, Churchill SW. Essentially exact characteristics of turbulent convection in a round tube Chemical Engineering Journal. 71: 163-173. DOI: 10.1016/S1385-8947(98)00135-1 |
0.496 |
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