Michael S. Denison - Publications

Affiliations: 
University of California, Davis, Davis, CA 
Area:
Molecular Biology, Toxicology, Biochemistry

205 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hawerkamp HC, Kislat A, Gerber PA, Pollet M, Rolfes KM, Soshilov AA, Denison MS, Momin AA, Arold ST, Datsi A, Braun SA, Oláh P, Lacouture ME, Krutmann J, Haarmann-Stemmann T, et al. Vemurafenib acts as an aryl hydrocarbon receptor antagonist: Implications for inflammatory cutaneous adverse events. Allergy. PMID 31269229 DOI: 10.1111/all.13972  1
2019 Guo W, Van Langenhove K, Vandermarken T, Denison MS, Elskens M, Baeyens W, Gao Y. In situ measurement of estrogenic activity in various aquatic systems using organic diffusive gradients in thin-film coupled with ERE-CALUX bioassay. Environment International. 127: 13-20. PMID 30897513 DOI: 10.1016/j.envint.2019.03.027  0.48
2018 Faber SC, Soshilov AA, Giani Tagliabue S, Bonati L, Denison MS. Comparative In Vitro and In Silico Analysis of the Selectivity of Indirubin as a Human Ah Receptor Agonist. International Journal of Molecular Sciences. 19. PMID 30201897 DOI: 10.3390/ijms19092692  1
2017 Guo W, Van Langenhove K, Denison MS, Baeyens WF, Elskens M, Gao Y. A Novel Tool for Estrogenic Activity Measurements in Water Using Diffusion Gradients in Thin-film Coupled with an Estrogen Bioassay. Analytical Chemistry. PMID 29151339 DOI: 10.1021/acs.analchem.7b03537  0.48
2017 Datta S, He G, Tomilov A, Sahdeo S, Denison MS, Cortopassi G. In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride. Environmental Health Perspectives. 125: 087015. PMID 28885978 DOI: 10.1289/EHP1404  0.4
2017 Denison MS, Faber SC. And Now for Something Completely Different: Diversity in Ligand-Dependent Activation of Ah Receptor Responses. Current Opinion in Toxicology. 2: 124-131. PMID 28845473 DOI: 10.1016/j.cotox.2017.01.006  0.52
2017 Denison MS, Faber SC. And Now for Something Completely Different: Diversity in Ligand-Dependent Activation of Ah Receptor Responses. Current Opinion in Toxicology. 2: 124-131. PMID 28845473 DOI: 10.1016/j.cotox.2017.01.006  0.52
2017 Anderson CG, Joshi G, Bair DA, Oriol C, He G, Parikh SJ, Denison MS, Scow KM. Use of nuclear receptor luciferase-based bioassays to detect endocrine active chemicals in a biosolids-biochar amended soil. Chemosphere. 181: 160-167. PMID 28437741 DOI: 10.1016/j.chemosphere.2017.04.035  0.4
2017 Corrada D, Denison MS, Bonati L. Structural modeling of the AhR:ARNT complex in the bHLH-PASA-PASB region elucidates the key determinants of dimerization. Molecular Biosystems. PMID 28393157 DOI: 10.1039/c7mb00005g  0.52
2017 Elshenawy OH, Abdelhamid G, Soshilov AA, Denison MS, El-Kadi AO. DOWN-REGULATION OF CYTOCHROME P450 1A1 BY MONOMETHYLARSONOUS ACID IN HUMAN HEPG2 CELLS. Toxicology Letters. PMID 28189647 DOI: 10.1016/j.toxlet.2017.02.012  1
2016 Corrada D, Soshilov AA, Denison MS, Bonati L. Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR Transformation. Plos Computational Biology. 12: e1004981. PMID 27295348 DOI: 10.1371/journal.pcbi.1004981  1
2016 Croes K, Van den Heuvel R, Van den Bril B, Staelens J, Denison MS, Van Langenhove K, Vandermarken T, Elskens M. Assessment of estrogenic and androgenic activity in PM10 air samples from an urban, industrial and rural area in Flanders (Belgium) using the CALUX bioassay. Environmental Research. 150: 66-72. PMID 27257826 DOI: 10.1016/j.envres.2016.05.044  0.32
2016 Bak SM, Iida M, Soshilov AA, Denison MS, Iwata H, Kim EY. Auto-induction mechanism of aryl hydrocarbon receptor 2 (AHR2) gene by TCDD-activated AHR1 and AHR2 in the red seabream (Pagrus major). Archives of Toxicology. PMID 27188387 DOI: 10.1007/s00204-016-1732-9  0.32
2016 Cole BJ, Brander SM, Jeffries KM, Hasenbein S, He G, Denison MS, Fangue NA, Connon RE. Changes in Menidia beryllina Gene Expression and In Vitro Hormone-Receptor Activation After Exposure to Estuarine Waters Near Treated Wastewater Outfalls. Archives of Environmental Contamination and Toxicology. PMID 27155869 DOI: 10.1007/s00244-016-0282-8  0.32
2016 Croes K, Debaillie P, Van den Bril B, Staelens J, Vandermarken T, Van Langenhove K, Denison MS, Leermakers M, Elskens M. Assessment of estrogenic activity in PM10 air samples with the ERE-CALUX bioassay: Method optimization and implementation at an urban location in Flanders (Belgium). Chemosphere. 144: 392-8. PMID 26383266 DOI: 10.1016/j.chemosphere.2015.09.020  1
2016 Vandermarken T, De Galan S, Croes K, Van Langenhove K, Vercammen J, Sanctorum H, Denison MS, Goeyens L, Elskens M, Baeyens W. Characterisation and implementation of the ERE-CALUX bioassay on indoor dust samples of kindergartens to assess estrogenic potencies. The Journal of Steroid Biochemistry and Molecular Biology. 155: 182-9. PMID 25595043 DOI: 10.1016/j.jsbmb.2015.01.005  1
2015 Khedidji S, Croes K, Yassaa N, Ladji R, Denison MS, Baeyens W, Elskens M. Assessment of dioxin-like activity in PM10 air samples from an industrial location in Algeria, using the DRE-CALUX bioassay. Environmental Science and Pollution Research International. PMID 26611627 DOI: 10.1007/s11356-015-5841-4  1
2015 Brennan JC, He G, Tsutsumi T, Zhao J, Wirth E, Fulton MH, Denison MS. Development of Species-Specific Ah Receptor-Responsive Third Generation CALUX Cell Lines with Enhanced Responsiveness and Improved Detection Limits. Environmental Science & Technology. 49: 11903-12. PMID 26366531 DOI: 10.1021/acs.est.5b02906  1
2015 Brennan JC, Bassal A, He G, Denison MS. Development of a recombinant human ovarian (BG1) cell line containing estrogen receptor α and β for improved detection of estrogenic/antiestrogenic chemicals. Environmental Toxicology and Chemistry / Setac. PMID 26139245 DOI: 10.1002/etc.3146  1
2015 Peng C, Muthusamy S, Xia Q, Lal V, Denison MS, Ng JC. Micronucleus formation by single and mixed heavy metals/loids and PAH compounds in HepG2 cells. Mutagenesis. PMID 26085548 DOI: 10.1093/mutage/gev021  1
2015 DeGroot DE, Franks DG, Higa T, Tanaka J, Hahn ME, Denison MS. Naturally Occurring Marine Brominated Indoles Are Aryl Hydrocarbon Receptor Ligands/Agonists. Chemical Research in Toxicology. 28: 1176-85. PMID 26001051 DOI: 10.1021/acs.chemrestox.5b00003  1
2015 Shoots J, Fraccalvieri D, Franks DG, Denison MS, Hahn ME, Bonati L, Powell WH. An Aryl Hydrocarbon Receptor from the Salamander Ambystoma mexicanum Exhibits Low Sensitivity to 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Environmental Science & Technology. 49: 6993-7001. PMID 25941739 DOI: 10.1021/acs.est.5b01299  1
2015 Joshi G, Schmidt R, Scow KM, Denison MS, Hristova KR. Gene mdpC plays a regulatory role in the methyl-tert-butyl ether degradation pathway of Methylibium petroleiphilum strain PM1. Fems Microbiology Letters. 362. PMID 25724531 DOI: 10.1093/femsle/fnv029  1
2015 Mexia N, Gaitanis G, Velegraki A, Soshilov A, Denison MS, Magiatis P. Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast. Archives of Biochemistry and Biophysics. 571: 16-20. PMID 25721496 DOI: 10.1016/j.abb.2015.02.023  1
2015 Maayah ZH, Ghebeh H, Alhaider AA, El-Kadi AO, Soshilov AA, Denison MS, Ansari MA, Korashy HM. Metformin inhibits 7,12-dimethylbenz[a]anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl hydrocarbon receptor signaling pathway. Toxicology and Applied Pharmacology. 284: 217-26. PMID 25697376 DOI: 10.1016/j.taap.2015.02.007  1
2015 Bittner GD, Denison MS, Yang CZ, Stoner MA, He G. Chemicals having estrogenic activity can be released from some bisphenol A-free, hard and clear, thermoplastic resins. Environmental Health : a Global Access Science Source. 14: 103. PMID 25477047 DOI: 10.1186/1476-069X-13-103  0.4
2015 Frauenstein K, Tigges J, Soshilov AA, Kado S, Raab N, Fritsche E, Haendeler J, Denison MS, Vogel CF, Haarmann-Stemmann T. Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2). Archives of Toxicology. 89: 1329-36. PMID 25082669 DOI: 10.1007/s00204-014-1321-8  1
2014 Novotna A, Korhonova M, Bartonkova I, Soshilov AA, Denison MS, Bogdanova K, Kolar M, Bednar P, Dvorak Z. Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor. Plos One. 9: e101832. PMID 25000292 DOI: 10.1371/journal.pone.0101832  1
2014 Bessede A, Gargaro M, Pallotta MT, Matino D, Servillo G, Brunacci C, Bicciato S, Mazza EM, Macchiarulo A, Vacca C, Iannitti R, Tissi L, Volpi C, Belladonna ML, Orabona C, ... ... Denison MS, et al. Aryl hydrocarbon receptor control of a disease tolerance defence pathway. Nature. 511: 184-90. PMID 24930766 DOI: 10.1038/nature13323  1
2014 Ghorbanzadeh M, van Ede KI, Larsson M, van Duursen MB, Poellinger L, Lücke-Johansson S, Machala M, P?n?íková K, Vondrá?ek J, van den Berg M, Denison MS, Ringsted T, Andersson PL. In vitro and in silico derived relative effect potencies of ah-receptor-mediated effects by PCDD/Fs and PCBs in rat, mouse, and guinea pig CALUX cell lines. Chemical Research in Toxicology. 27: 1120-32. PMID 24901989 DOI: 10.1021/tx5001255  1
2014 Soshilov AA, Denison MS. Ligand promiscuity of aryl hydrocarbon receptor agonists and antagonists revealed by site-directed mutagenesis. Molecular and Cellular Biology. 34: 1707-19. PMID 24591650 DOI: 10.1128/MCB.01183-13  1
2014 Addeck A, Croes K, Van Langenhove K, Denison MS, Afify AS, Gao Y, Elskens M, Baeyens W. Time-integrated monitoring of dioxin-like polychlorinated biphenyls (dl-PCBs) in aquatic environments using the ceramic toximeter and the CALUX bioassay. Talanta. 120: 413-8. PMID 24468390 DOI: 10.1016/j.talanta.2013.12.017  1
2014 Vogel CF, Khan EM, Leung PS, Gershwin ME, Chang WL, Wu D, Haarmann-Stemmann T, Hoffmann A, Denison MS. Cross-talk between aryl hydrocarbon receptor and the inflammatory response: a role for nuclear factor-κB. The Journal of Biological Chemistry. 289: 1866-75. PMID 24302727 DOI: 10.1074/jbc.M113.505578  1
2014 DeGroot DE, Hayashi A, Denison MS. Lack of ligand-selective binding of the aryl hydrocarbon receptor to putative DNA binding sites regulating expression of Bax and paraoxonase 1 genes. Archives of Biochemistry and Biophysics. 541: 13-20. PMID 24200861 DOI: 10.1016/j.abb.2013.10.021  1
2014 Anwar-Mohamed A, Elshenawy OH, Soshilov AA, Denison MS, Chris Le X, Klotz LO, El-Kadi AO. Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms. Free Radical Biology & Medicine. 67: 171-87. PMID 24161444 DOI: 10.1016/j.freeradbiomed.2013.10.810  1
2014 DeGroot DE, Denison MS. Nucleotide specificity of DNA binding of the aryl hydrocarbon receptor:ARNT complex is unaffected by ligand structure. Toxicological Sciences : An Official Journal of the Society of Toxicology. 137: 102-13. PMID 24136190 DOI: 10.1093/toxsci/kft234  1
2014 Addeck A, Croes K, Van Langenhove K, Denison MS, Elhamalawy A, Elskens M, Baeyens W. Time-integrated monitoring of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) in urban and industrial wastewaters using a ceramic toximeter and the CALUX bioassay. Chemosphere. 94: 27-35. PMID 24075528 DOI: 10.1016/j.chemosphere.2013.08.075  1
2014 He G, Zhao J, Brennan JC, Affatato AA, Zhao B, Rice RH, Denison MS. Cell-based assays for identification of aryl hydrocarbon receptor (AhR) activators Methods in Pharmacology and Toxicology. 221-235. DOI: 10.1007/978-1-62703-742-6-13  1
2014 Soshilov AA, Denison MS. DNA binding (gel retardation assay) analysis for identification of aryl hydrocarbon (Ah) receptor agonists and antagonists Methods in Pharmacology and Toxicology. 207-219. DOI: 10.1007/978-1-62703-742-6-12  1
2013 Brander SM, Connon RE, He G, Hobbs JA, Smalling KL, Teh SJ, White JW, Werner I, Denison MS, Cherr GN. From 'omics to otoliths: responses of an estuarine fish to endocrine disrupting compounds across biological scales. Plos One. 8: e74251. PMID 24086325 DOI: 10.1371/journal.pone.0074251  1
2013 Hu Q, He G, Zhao J, Soshilov A, Denison MS, Zhang A, Yin H, Fraccalvieri D, Bonati L, Xie Q, Zhao B. Ginsenosides are novel naturally-occurring aryl hydrocarbon receptor ligands. Plos One. 8: e66258. PMID 23776647 DOI: 10.1371/journal.pone.0066258  1
2013 Brennan JC, Denison MS, Holstege DM, Magiatis P, Dallas JL, Gutierrez EG, Soshilov AA, Millam JR. 2,3-cis-2R,3R-(-)-epiafzelechin-3-O-p-coumarate, a novel flavan-3-ol isolated from Fallopia convolvulus seed, is an estrogen receptor agonist in human cell lines. Bmc Complementary and Alternative Medicine. 13: 133. PMID 23768005 DOI: 10.1186/1472-6882-13-133  1
2013 Kamenickova A, Anzenbacherova E, Pavek P, Soshilov AA, Denison MS, Zapletalova M, Anzenbacher P, Dvorak Z. Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. Toxicology Letters. 221: 1-8. PMID 23735880 DOI: 10.1016/j.toxlet.2013.05.007  1
2013 Croes K, Colles A, Koppen G, De Galan S, Vandermarken T, Govarts E, Bruckers L, Nelen V, Schoeters G, Van Larebeke N, Denison MS, Mampaey M, Baeyens W. Determination of PCDD/Fs, PBDD/Fs and dioxin-like PCBs in human milk from mothers residing in the rural areas in Flanders, using the CALUX bioassay and GC-HRMS Talanta. 113: 99-105. PMID 23708629 DOI: 10.1016/j.talanta.2013.03.086  1
2013 van den Berg M, Denison MS, Birnbaum LS, Devito MJ, Fiedler H, Falandysz J, Rose M, Schrenk D, Safe S, Tohyama C, Tritscher A, Tysklind M, Peterson RE. Polybrominated dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds. Toxicological Sciences : An Official Journal of the Society of Toxicology. 133: 197-208. PMID 23492812 DOI: 10.1093/toxsci/kft070  1
2013 Magiatis P, Pappas P, Gaitanis G, Mexia N, Melliou E, Galanou M, Vlachos C, Stathopoulou K, Skaltsounis AL, Marselos M, Velegraki A, Denison MS, Bassukas ID. Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) receptor detected in diseased human skin. The Journal of Investigative Dermatology. 133: 2023-30. PMID 23448877 DOI: 10.1038/jid.2013.92  1
2013 Zhao B, Bohonowych JE, Timme-Laragy A, Jung D, Affatato AA, Rice RH, Di Giulio RT, Denison MS. Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin) receptor. Plos One. 8: e56860. PMID 23441220 DOI: 10.1371/journal.pone.0056860  1
2013 Kamenickova A, Anzenbacherova E, Pavek P, Soshilov AA, Denison MS, Anzenbacher P, Dvorak Z. Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. Toxicology Letters. 218: 253-9. PMID 23419638 DOI: 10.1016/j.toxlet.2013.01.020  1
2013 Odio C, Holzman SA, Denison MS, Fraccalvieri D, Bonati L, Franks DG, Hahn ME, Powell WH. Specific ligand binding domain residues confer low dioxin responsiveness to AHR1β of Xenopus laevis. Biochemistry. 52: 1746-54. PMID 23394719 DOI: 10.1021/bi301722k  1
2013 Fraccalvieri D, Soshilov AA, Karchner SI, Franks DG, Pandini A, Bonati L, Hahn ME, Denison MS. Comparative analysis of homology models of the AH receptor ligand binding domain: verification of structure-function predictions by site-directed mutagenesis of a nonfunctional receptor. Biochemistry. 52: 714-25. PMID 23286227 DOI: 10.1021/bi301457f  1
2012 Brander SM, He G, Smalling KL, Denison MS, Cherr GN. The in vivo estrogenic and in vitro anti-estrogenic activity of permethrin and bifenthrin. Environmental Toxicology and Chemistry / Setac. 31: 2848-55. PMID 23007834 DOI: 10.1002/etc.2019  1
2012 Croes K, Vandermarken T, Van Langenhove K, Elskens M, Desmedt M, Roekens E, Denison MS, Van Larebeke N, Baeyens W. Analysis of PCDD/Fs and dioxin-like PCBs in atmospheric deposition samples from the Flemish measurement network: Correlation between the CALUX bioassay and GC-HRMS Chemosphere. 88: 881-887. PMID 22560702 DOI: 10.1016/j.chemosphere.2012.03.097  1
2012 Wall RJ, He G, Denison MS, Congiu C, Onnis V, Fernandes A, Bell DR, Rose M, Rowlands JC, Balboni G, Mellor IR. Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context. Toxicology. 297: 26-33. PMID 22507882 DOI: 10.1016/j.tox.2012.03.011  1
2012 Tiong CT, Chen C, Zhang SJ, Li J, Soshilov A, Denison MS, Lee LS, Tam VH, Wong SP, Xu HE, Yong EL. A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein. Carcinogenesis. 33: 1089-97. PMID 22345291 DOI: 10.1093/carcin/bgs110  1
2012 El Gendy MA, Soshilov AA, Denison MS, El-Kadi AO. Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 50: 353-62. PMID 22037238 DOI: 10.1016/j.fct.2011.10.052  1
2012 El Gendy MA, Soshilov AA, Denison MS, El-Kadi AO. Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol. Toxicology Letters. 208: 51-61. PMID 22001777 DOI: 10.1016/j.toxlet.2011.09.030  1
2012 Wang Y, Yang D, Chang A, Chan WK, Zhao B, Denison MS, Xue L. Synthesis of a ligand-quencher conjugate for the ligand binding study of the aryl hydrocarbon receptor using a FRET assay Medicinal Chemistry Research. 21: 711-721. DOI: 10.1007/s00044-011-9575-7  1
2011 Motto I, Bordogna A, Soshilov AA, Denison MS, Bonati L. New aryl hydrocarbon receptor homology model targeted to improve docking reliability. Journal of Chemical Information and Modeling. 51: 2868-81. PMID 21981577 DOI: 10.1021/ci2001617  1
2011 Croes K, Van Langenhove K, Hond ED, Bruckers L, Colles A, Koppen G, Loots I, Nelen V, Schoeters G, Nawrot T, Van Larebeke N, Denison MS, Vandermarken T, Elskens M, Baeyens W. Quantification of PCDD/Fs and dioxin-like PCBs in small amounts of human serum using the sensitive H1L7.5c1 mouse hepatoma cell line: Optimization and analysis of human serum samples from adolescents of the Flemish Environment and Health Study (FLEHS II) Talanta. 85: 2484-2491. PMID 21962672 DOI: 10.1016/j.talanta.2011.07.103  1
2011 Denison MS, Soshilov AA, He G, DeGroot DE, Zhao B. Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 1-22. PMID 21908767 DOI: 10.1093/toxsci/kfr218  1
2011 Van Langenhove K, Croes K, Denison MS, Elskens M, Baeyens W. The CALUX bio-assay: analytical comparison between mouse hepatoma cell lines with a low (H1L6.1c3) and high (H1L7.5c1) number of dioxin response elements. Talanta. 85: 2039-46. PMID 21872055 DOI: 10.1016/j.talanta.2011.07.042  1
2011 Elskens M, Baston DS, Stumpf C, Haedrich J, Keupers I, Croes K, Denison MS, Baeyens W, Goeyens L. CALUX measurements: statistical inferences for the dose-response curve. Talanta. 85: 1966-73. PMID 21872045 DOI: 10.1016/j.talanta.2011.07.014  1
2011 Soshilov A, Denison MS. Ligand displaces heat shock protein 90 from overlapping binding sites within the aryl hydrocarbon receptor ligand-binding domain. The Journal of Biological Chemistry. 286: 35275-82. PMID 21856752 DOI: 10.1074/jbc.M111.246439  1
2011 He G, Tsutsumi T, Zhao B, Baston DS, Zhao J, Heath-Pagliuso S, Denison MS. Third-generation Ah receptor-responsive luciferase reporter plasmids: amplification of dioxin-responsive elements dramatically increases CALUX bioassay sensitivity and responsiveness. Toxicological Sciences : An Official Journal of the Society of Toxicology. 123: 511-22. PMID 21775728 DOI: 10.1093/toxsci/kfr189  1
2011 Korashy HM, Anwar-Mohamed A, Soshilov AA, Denison MS, El-Kadi AO. The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation. Chemical Research in Toxicology. 24: 1540-8. PMID 21732638 DOI: 10.1021/tx200141p  1
2011 Aung HH, Lame MW, Gohil K, He G, Denison MS, Rutledge JC, Wilson DW. Comparative gene responses to collected ambient particles in vitro: endothelial responses. Physiological Genomics. 43: 917-29. PMID 21652769 DOI: 10.1152/physiolgenomics.00051.2011  1
2011 He G, Zhao B, Denison MS. Identification of benzothiazole derivatives and polycyclic aromatic hydrocarbons as aryl hydrocarbon receptor agonists present in tire extracts. Environmental Toxicology and Chemistry / Setac. 30: 1915-25. PMID 21590714 DOI: 10.1002/etc.581  1
2011 Baston DS, Denison MS. Considerations for potency equivalent calculations in the Ah receptor-based CALUX bioassay: normalization of superinduction results for improved sample potency estimation. Talanta. 83: 1415-21. PMID 21238730 DOI: 10.1016/j.talanta.2010.11.035  1
2011 Croes K, Van Langenhove K, Elskens M, Desmedt M, Roekens E, Kotz A, Denison MS, Baeyens W. Analysis of PCDD/Fs and dioxin-like PCBs in atmospheric deposition samples from the Flemish measurement network: Optimization and validation of a new CALUX bioassay method Chemosphere. 82: 718-724. PMID 21094512 DOI: 10.1016/j.chemosphere.2010.10.092  1
2011 Lee YC, Oslund KL, Thai P, Velichko S, Fujisawa T, Duong T, Denison MS, Wu R. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced MUC5AC expression: aryl hydrocarbon receptor-independent/EGFR/ERK/p38-dependent SP1-based transcription. American Journal of Respiratory Cell and Molecular Biology. 45: 270-6. PMID 20971882 DOI: 10.1165/rcmb.2010-0313OC  1
2011 Degroot D, He G, Fraccalvieri D, Bonati L, Pandini A, Denison MS. AHR Ligands: Promiscuity in Binding and Diversity in Response The Ah Receptor in Biology and Toxicology. 63-79. DOI: 10.1002/9781118140574.ch4  1
2010 Kennedy K, Macova M, Bartkow ME, Hawker DW, Zhao B, Denison MS, Mueller JF. Effect based monitoring of seasonal ambient air exposures in Australia sampled by PUF passive air samplers. Atmospheric Pollution Research. 1: 50-58. PMID 21552507 DOI: 10.5094/APR.2010.008  1
2010 Zhao B, Baston DS, Khan E, Sorrentino C, Denison MS. Enhancing the response of CALUX and CAFLUX cell bioassays for quantitative detection of dioxin-like compounds. Science China. Chemistry. 53: 1010-1016. PMID 21394221 DOI: 10.1007/s11426-010-0142-8  1
2010 Boitano AE, Wang J, Romeo R, Bouchez LC, Parker AE, Sutton SE, Walker JR, Flaveny CA, Perdew GH, Denison MS, Schultz PG, Cooke MP. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science (New York, N.Y.). 329: 1345-8. PMID 20688981 DOI: 10.1126/science.1191536  1
2010 Zhao B, Degroot DE, Hayashi A, He G, Denison MS. CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 393-403. PMID 20634293 DOI: 10.1093/toxsci/kfq217  1
2010 Petkov PI, Rowlands JC, Budinsky R, Zhao B, Denison MS, Mekenyan O. Mechanism-based common reactivity pattern (COREPA) modelling of aryl hydrocarbon receptor binding affinity Sar and Qsar in Environmental Research. 21: 187-214. PMID 20373220 DOI: 10.1080/10629360903570933  1
2009 Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environmental Health Perspectives. 117: 1867-72. PMID 20049205 DOI: 10.1289/ehp.0900834  1
2009 Pandini A, Soshilov AA, Song Y, Zhao J, Bonati L, Denison MS. Detection of the TCDD binding-fingerprint within the Ah receptor ligand binding domain by structurally driven mutagenesis and functional analysis. Biochemistry. 48: 5972-83. PMID 19456125 DOI: 10.1021/bi900259z  1
2009 Kanematsu M, Hayashi A, Denison MS, Young TM. Characterization and potential environmental risks of leachate from shredded rubber mulches. Chemosphere. 76: 952-8. PMID 19450864 DOI: 10.1016/j.chemosphere.2009.04.026  1
2009 Kennedy K, Macova M, Leusch F, Bartkow ME, Hawker DW, Zhao B, Denison MS, Mueller JF. Assessing indoor air exposures using passive sampling with bioanalytical methods for estrogenicity and aryl hydrocarbon receptor activity. Analytical and Bioanalytical Chemistry. 394: 1413-21. PMID 19430962 DOI: 10.1007/s00216-009-2825-6  1
2009 Jaikanlaya C, Settachan D, Denison MS, Ruchirawat M, van den Berg M. PCBs contamination in seafood species at the Eastern Coast of Thailand. Chemosphere. 76: 239-49. PMID 19375780 DOI: 10.1016/j.chemosphere.2009.03.018  1
2009 Palumbo AJ, Denison MS, Doroshov SI, Tjeerdema RS. Reduction of vitellogenin synthesis by an aryl hydrocarbon receptor agonist in the white sturgeon (Acipenser transmontamus). Environmental Toxicology and Chemistry / Setac. 28: 1749-55. PMID 19292566 DOI: 10.1897/08-481.1  1
2009 Rochester JR, Klasing KC, Stevenson L, Denison MS, Berry W, Millam JR. Dietary red clover (Trifolium pratense) induces oviduct growth and decreases ovary and testes growth in Japanese quail chicks. Reproductive Toxicology (Elmsford, N.Y.). 27: 63-71. PMID 19103282 DOI: 10.1016/j.reprotox.2008.11.056  1
2009 La Merrill M, Baston DS, Denison MS, Birnbaum LS, Pomp D, Threadgill DW. Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat. American Journal of Physiology. Endocrinology and Metabolism. 296: E203-10. PMID 18840765 DOI: 10.1152/ajpendo.90368.2008  1
2008 Soshilov A, Denison MS. Role of the Per/Arnt/Sim domains in ligand-dependent transformation of the aryl hydrocarbon receptor. The Journal of Biological Chemistry. 283: 32995-3005. PMID 18806268 DOI: 10.1074/jbc.M802414200  1
2008 Ahn KC, Zhao B, Chen J, Cherednichenko G, Sanmarti E, Denison MS, Lasley B, Pessah IN, Kültz D, Chang DP, Gee SJ, Hammock BD. In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens. Environmental Health Perspectives. 116: 1203-10. PMID 18795164 DOI: 10.1289/ehp.11200  1
2008 Lawrence BP, Denison MS, Novak H, Vorderstrasse BA, Harrer N, Neruda W, Reichel C, Woisetschläger M. Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low-molecular-weight compound. Blood. 112: 1158-65. PMID 18270326 DOI: 10.1182/blood-2007-08-109645  1
2008 Bohonowych JE, Zhao B, Timme-Laragy A, Jung D, Di Giulio RT, Denison MS. Newspapers and newspaper ink contain agonists for the ah receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 102: 278-90. PMID 18203687 DOI: 10.1093/toxsci/kfn011  1
2007 Cahill TM, Groskova D, Charles MJ, Sanborn JR, Denison MS, Baker L. Atmospheric concentrations of polybrominated diphenyl ethers at near-source sites. Environmental Science & Technology. 41: 6370-7. PMID 17948781 DOI: 10.1021/es070844j  1
2007 Brown DJ, Orelien J, Gordon JD, Chu AC, Chu MD, Nakamura M, Handa H, Kayama F, Denison MS, Clark GC. Mathematical model developed for environmental samples: prediction of GC/MS dioxin TEQ from XDS-CALUX bioassay data. Environmental Science & Technology. 41: 4354-60. PMID 17626436 DOI: 10.1021/es062602+  1
2007 Nording M, Denison MS, Baston D, Persson Y, Spinnel E, Haglund P. Analysis of dioxins in contaminated soils with the calux and caflux bioassays, an immunoassay, and gas chromatography/high-resolution mass spectrometry. Environmental Toxicology and Chemistry / Setac. 26: 1122-9. PMID 17571676 DOI: 10.1897/06-458R.1  1
2007 Bohonowych JE, Denison MS. Persistent binding of ligands to the aryl hydrocarbon receptor. Toxicological Sciences : An Official Journal of the Society of Toxicology. 98: 99-109. PMID 17431010 DOI: 10.1093/toxsci/kfm085  1
2007 Hu W, Sorrentino C, Denison MS, Kolaja K, Fielden MR. Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro. Molecular Pharmacology. 71: 1475-86. PMID 17327465 DOI: 10.1124/mol.106.032748  1
2007 Pandini A, Denison MS, Song Y, Soshilov AA, Bonati L. Structural and functional characterization of the aryl hydrocarbon receptor ligand binding domain by homology modeling and mutational analysis. Biochemistry. 46: 696-708. PMID 17223691 DOI: 10.1021/bi061460t  1
2006 Zhao B, Baston DS, Hammock B, Denison MS. Interaction of diuron and related substituted phenylureas with the Ah receptor pathway. Journal of Biochemical and Molecular Toxicology. 20: 103-13. PMID 16788953 DOI: 10.1002/jbt.20126  1
2006 Peters AK, Leonards PE, Zhao B, Bergman A, Denison MS, Van den Berg M. Determination of in vitro relative potency (REP) values for mono-ortho polychlorinated biphenyls after purification with active charcoal Toxicology Letters. 165: 230-241. PMID 16750337 DOI: 10.1016/j.toxlet.2006.04.005  1
2006 Klein GP, Hodge EM, Diamond ML, Yip A, Dann T, Stern G, Denison MS, Harper PA. Gas-phase ambient air contaminants exhibit significant dioxin-like and estrogen-like activity in vitro. Environmental Health Perspectives. 114: 697-703. PMID 16675423 DOI: 10.1289/ehp.8496  1
2006 Peters AK, Nijmeijer S, Gradin K, Backlund M, Bergman A, Poellinger L, Denison MS, Van den Berg M. Interactions of polybrominated diphenyl ethers with the aryl hydrocarbon receptor pathway Toxicological Sciences. 92: 133-142. PMID 16601081 DOI: 10.1093/toxsci/kfj186  1
2005 Windal I, Denison MS, Birnbaum LS, Van Wouwe N, Baeyens W, Goeyens L. Chemically activated luciferase gene expression (CALUX) cell bioassay analysis for the estimation of dioxin-like activity: critical parameters of the CALUX procedure that impact assay results. Environmental Science & Technology. 39: 7357-64. PMID 16245802 DOI: 10.1021/es0504993  1
2005 Jeong SH, Cho JH, Park JM, Denison MS. Rapid bioassay for the determination of dioxins and dioxin-like PCDFs and PCBs in meat and animal feeds. Journal of Analytical Toxicology. 29: 156-62. PMID 15842757  1
2005 Hall LC, Rogers JM, Denison MS, Johnson ML. Identification of the herbicide Surflan and its active ingredient oryzalin, a dinitrosulfonamide, as xenoestrogens. Archives of Environmental Contamination and Toxicology. 48: 201-8. PMID 15696347 DOI: 10.1007/s00244-003-0164-8  1
2004 Denison MS, Zhao B, Baston DS, Clark GC, Murata H, Han D. Recombinant cell bioassay systems for the detection and relative quantitation of halogenated dioxins and related chemicals. Talanta. 63: 1123-33. PMID 18969542 DOI: 10.1016/j.talanta.2004.05.032  1
2004 Peters AK, van Londen K, Bergman A, Bohonowych J, Denison MS, van den Berg M, Sanderson JT. Effects of polybrominated diphenyl ethers on basal and TCDD-induced ethoxyresorufin activity and cytochrome P450-1A1 expression in MCF-7, HepG2, HepG2, and H4IIE cells Toxicological Sciences. 82: 488-496. PMID 15456928 DOI: 10.1093/toxsci/kfh284  1
2004 Sanderson JT, Hordijk J, Denison MS, Springsteel MF, Nantz MH, van den Berg M. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 82: 70-9. PMID 15319488 DOI: 10.1093/toxsci/kfh257  1
2004 Brown DJ, Van Overmeire I, Goeyens L, Denison MS, De Vito MJ, Clark GC. Analysis of Ah receptor pathway activation by brominated flame retardants. Chemosphere. 55: 1509-18. PMID 15099731 DOI: 10.1016/j.chemosphere.2003.10.019  1
2004 Han D, Nagy SR, Denison MS. Comparison of recombinant cell bioassays for the detection of Ah receptor agonists. Biofactors (Oxford, England). 20: 11-22. PMID 15096657  1
2003 Monk SA, Denison MS, Rice RH. Reversible stepwise negative regulation of CYP1A1 in cultured rat epidermal cells. Archives of Biochemistry and Biophysics. 419: 158-69. PMID 14592459 DOI: 10.1016/j.abb.2003.09.004  1
2003 Jeuken A, Keser BJ, Khan E, Brouwer A, Koeman J, Denison MS. Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits. Journal of Agricultural and Food Chemistry. 51: 5478-87. PMID 12926901 DOI: 10.1021/jf030252u  1
2003 Arrieta DE, Ontiveros CC, Li WW, Garcia JH, Denison MS, McDonald JD, Burchiel SW, Washburn BS. Aryl hydrocarbon receptor-mediated activity of particulate organic matter from the Paso del Norte airshed along the U.S.-Mexico border. Environmental Health Perspectives. 111: 1299-305. PMID 12896850  1
2003 Denison MS, Nagy SR. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annual Review of Pharmacology and Toxicology. 43: 309-34. PMID 12540743 DOI: 10.1146/annurev.pharmtox.43.100901.135828  1
2002 Denison MS, Rogers JM, Rushing SR, Jones CL, Tetangco SC, Heath-Pagliuso S. Analysis of the aryl hydrocarbon receptor (AhR) signal transduction pathway. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit4.8. PMID 20945300 DOI: 10.1002/0471140856.tx0408s11  1
2002 Ziccardi MH, Gardner IA, Mazet JA, Denison MS. Application of the luciferase cell culture bioassay for the detection of refined petroleum products. Marine Pollution Bulletin. 44: 983-91. PMID 12474956 DOI: 10.1016/S0025-326X(02)00128-5  1
2002 Lashley MR, Niedzinski EJ, Rogers JM, Denison MS, Nantz MH. Synthesis and estrogen receptor affinity of a 4-hydroxytamoxifen-labeled ligand for diagnostic imaging. Bioorganic & Medicinal Chemistry. 10: 4075-82. PMID 12413861 DOI: 10.1016/S0968-0896(02)00329-2  1
2002 Han D, Denison MS, Tachibana H, Yamada K. Effects of estrogenic compounds on immunoglobulin production by mouse splenocytes Biological and Pharmaceutical Bulletin. 25: 1263-1267. PMID 12392075 DOI: 10.1248/bpb.25.1263  1
2002 Ziccardi MH, Gardner IA, Denison MS. Application of the luciferase recombinant cell culture bioassay system for the analysis of polycyclic aromatic hydrocarbons. Environmental Toxicology and Chemistry / Setac. 21: 2027-33. PMID 12371477  1
2002 Han DH, Denison MS, Tachibana H, Yamada K. Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids. Bioscience, Biotechnology, and Biochemistry. 66: 1479-87. PMID 12224631 DOI: 10.1271/bbb.66.1479  1
2002 Denison MS, Pandini A, Nagy SR, Baldwin EP, Bonati L. Ligand binding and activation of the Ah receptor. Chemico-Biological Interactions. 141: 3-24. PMID 12213382 DOI: 10.1016/S0009-2797(02)00063-7  1
2002 Nagy SR, Denison MS. Specificity of nuclear protein binding to a CYP1A1 negative regulatory element. Biochemical and Biophysical Research Communications. 296: 799-805. PMID 12200118 DOI: 10.1016/S0006-291X(02)00945-2  1
2002 Natarajan K, Overstreet JW, Rogers JM, Denison MS, Chen J, Lohstroh PN, McConnell DS, Lasley BL. Detection of xenoestrogens in serum after immunoprecipitation of endogenous steroidal estrogens. Environmental Health Perspectives. 110: 791-5. PMID 12153760  1
2002 Rushing SR, Denison MS. The silencing mediator of retinoic acid and thyroid hormone receptors can interact with the aryl hydrocarbon (Ah) receptor but fails to repress Ah receptor-dependent gene expression. Archives of Biochemistry and Biophysics. 403: 189-201. PMID 12139968 DOI: 10.1016/S0003-9861(02)00233-3  1
2002 Ziccardi MH, Mazet JA, Gardner IA, Boyce WM, Denison MS. Validation of a cell culture bioassay for detection of petroleum exposure in mink (Mustela vison) as a model for detection in sea otters (Enhydra lutris). American Journal of Veterinary Research. 63: 963-8. PMID 12118676  1
2002 Rogers JM, Denison MS. Analysis of the antiestrogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in human ovarian carcinoma BG-1 cells. Molecular Pharmacology. 61: 1393-403. PMID 12021401 DOI: 10.1124/mol.61.6.1393  1
2002 Liu PC, Moreno-Aliaga MJ, Dunlap DY, Hu XM, Denison MS, Matsumura F. Correlation between the high expression of C/EBPbeta protein in F442A cells and their relative resistance to antiadipogenic action of TCDD in comparison to 3T3-L1 cells. Journal of Biochemical and Molecular Toxicology. 16: 70-83. PMID 11979424 DOI: 10.1002/jbt.10020  1
2002 Nagy SR, Sanborn JR, Hammock BD, Denison MS. Development of a green fluorescent protein-based cell bioassay for the rapid and inexpensive detection and characterization of ah receptor agonists. Toxicological Sciences : An Official Journal of the Society of Toxicology. 65: 200-10. PMID 11812924 DOI: 10.1093/toxsci/65.2.200  1
2002 Nagy SR, Liu G, Lam KS, Denison MS. Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay. Biochemistry. 41: 861-8. PMID 11790108 DOI: 10.1021/bi011373v  1
2002 Denison MS, Perdew GH. Introductory comments Chemico-Biological Interactions. 141: 1. DOI: 10.1016/S0009-2797(02)00062-5  1
2001 Seidel SD, Winters GM, Rogers WJ, Ziccardi MH, Li V, Keser B, Denison MS. Activation of the Ah receptor signaling pathway by prostaglandins Journal of Biochemical and Molecular Toxicology. 15: 187-196. PMID 11673847 DOI: 10.1002/jbt.16  1
2001 Monk SA, Denison MS, Rice RH. Transient expression of CYP1A1 in rat epithelial cells cultured in suspension Archives of Biochemistry and Biophysics. 393: 154-162. PMID 11516172 DOI: 10.1006/abbi.2001.2475  1
2001 Van Overmeire I, Clark GC, Brown DJ, Chu MD, Marcus Cooke W, Denison MS, Baeyens W, Srebrnik S, Goeyens L. Trace contamination with dioxin-like chemicals: Evaluation of bioassay-based TEQ determination for hazard assessment and regulatory responses Environmental Science and Policy. 4: 345-357. DOI: 10.1016/S1462-9011(01)00037-5  1
2000 Williams SN, Shih H, Guenette DK, Brackney W, Denison MS, Pickwell GV, Quattrochi LC. Comparative studies on the effects of green tea extracts and individual tea catechins on human CYP1A gene expression. Chemico-Biological Interactions. 128: 211-29. PMID 11064004 DOI: 10.1016/S0009-2797(00)00204-0  1
2000 Rogers JM, Denison MS. Recombinant cell bioassays for endocrine disruptors: Development of a stably transfected human ovarian cell line for the detection of estrogenic and anti-estrogenic chemicals In Vitro and Molecular Toxicology: Journal of Basic and Applied Research. 13: 67-82. PMID 10900408  1
2000 Seidel SD, Li V, Winter GM, Rogers WJ, Martinez EI, Denison MS. Ah receptor-based chemical screening bioassays: application and limitations for the detection of Ah receptor agonists. Toxicological Sciences : An Official Journal of the Society of Toxicology. 55: 107-15. PMID 10788565  1
2000 Ziccardi MH, Gardner IA, Denison MS. Development and modification of a recombinant cell bioassay to directly detect halogenated and polycyclic aromatic hydrocarbons in serum Toxicological Sciences. 54: 183-193. PMID 10746945  1
2000 Lee CZ, Royce FH, Denison MS, Pinkerton KE. Effect of in utero and postnatal exposure to environmental tobacco smoke on the developmental expression of pulmonary cytochrome P450 monooxygenases. Journal of Biochemical and Molecular Toxicology. 14: 121-30. PMID 10711627 DOI: 10.1002/(SICI)1099-0461(2000)14:3<121::AID-JBT1>3.0.CO;2-U  1
2000 Garrison PM, Rogers JM, Brackney WR, Denison MS. Effects of histone deacetylase inhibitors on the Ah receptor gene promoter Archives of Biochemistry and Biophysics. 374: 161-171. PMID 10666294 DOI: 10.1006/abbi.1999.1620  1
2000 Garrison PM, Denison MS. Analysis of the murine AhR gene promoter Journal of Biochemical and Molecular Toxicology. 14: 1-10. PMID 10561076  1
1999 Seidel SD, Denison MS. Differential gene expression in wild-type and Arnt-defective mouse hepatoma (Hepa1c1c7) cells Toxicological Sciences. 52: 217-225. PMID 10630574  1
1999 Tian Y, Ke S, Denison MS, Rabson AB, Gallo MA. Ah receptor and NF-κB interactions, a potential mechanism for dioxin toxicity Journal of Biological Chemistry. 274: 510-515. PMID 9867872 DOI: 10.1074/jbc.274.1.510  1
1999 Levine SL, Oris JT, Denison MS. Modulation of CYP1A expression in rainbow trout by a technical grade formulation of propiconazole Environmental Toxicology and Chemistry. 18: 2565-2573. DOI: 10.1002/etc.5620181125  1
1998 Denison MS, Phelan D, Winter GM, Ziccardi MH. Carbaryl, a carbamate insecticide, is a ligand for the hepatic Ah (dioxin) receptor. Toxicology and Applied Pharmacology. 152: 406-14. PMID 9853009 DOI: 10.1006/taap.1998.9999  1
1998 Denison MS, Heath-Pagliuso S. The Ah receptor: A regulator of the biochemical and toxicological actions of structurally diverse chemicals Bulletin of Environmental Contamination and Toxicology. 61: 557-568. PMID 9841714 DOI: 10.1007/PL00002973  1
1998 Phelan D, Winter GM, Rogers WJ, Lam JC, Denison MS. Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin. Archives of Biochemistry and Biophysics. 357: 155-63. PMID 9721195 DOI: 10.1006/abbi.1998.0814  1
1998 Besselink HT, Denison MS, Hahn ME, Karchner SI, Vethaak AD, Koeman JH, Brouwer A. Low inducibility of cyp1a activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): Characterization of the Ah receptor and the role of CYP1A inhibition Toxicological Sciences. 43: 161-171. PMID 9710958 DOI: 10.1006/toxs.1998.2455  1
1998 Heath-Pagliuso S, Rogers WJ, Tullis K, Seidel SD, Cenijn PH, Brouwer A, Denison MS. Activation of the Ah receptor by tryptophan and tryptophan metabolites Biochemistry. 37: 11508-11515. PMID 9708986 DOI: 10.1021/bi980087p  1
1998 Phelan DM, Brackney WR, Denison MS. The Ah receptor can bind ligand in the absence of receptor-associated heat-shock protein 90 Archives of Biochemistry and Biophysics. 353: 47-54. PMID 9578599 DOI: 10.1006/abbi.1997.0614  1
1998 Johnson ML, Salveson A, Holmes L, Denison MS, Fry DM. Environmental estrogens in agricultural drain water from the Central Valley of California Bulletin of Environmental Contamination and Toxicology. 60: 609-614. PMID 9557200 DOI: 10.1007/s001289900669  1
1997 Washburn BS, Rein KS, Baden DG, Walsh PJ, Hinton DE, Tullis K, Denison MS. Brevetoxin-6 (PbTx-6), a nonaromatic marine neurotoxin, is a ligand of the aryl hydrocarbon receptor Archives of Biochemistry and Biophysics. 343: 149-156. PMID 9224724 DOI: 10.1006/abbi.1997.0149  1
1997 Murk AJ, Leonards PEG, Bulder AS, Jonas AS, Rozemeijer MJC, Denison MS, Koeman JH, Brouwer A. The calux (chemical-activated luciferase expression) assay adapted and validated for measuring TCDD equivalents in blood plasma Environmental Toxicology and Chemistry. 16: 1583-1589. DOI: 10.1897/1551-5028(1997)016<1583:TCCALE>2.3.CO;2  1
1997 Richter CA, Tieber VL, Denison MS, Giesy JP. An in vitro rainbow trout cell bioassay for aryl hydrocarbon receptor- mediated toxins Environmental Toxicology and Chemistry. 16: 543-550. DOI: 10.1897/1551-5028(1997)016<0543:AIVRTC>2.3.CO;2  1
1996 Gebremichael A, Tullis K, Denison MS, Cheek JM, Pinkerton KE. Ah-receptor-dependent modulation of gene expression by aged and diluted sidestream cigarette smoke Toxicology and Applied Pharmacology. 141: 76-83. PMID 8917678 DOI: 10.1006/taap.1996.0262  1
1996 Villalobos SA, Anderson MJ, Denison MS, Hinton DE, Tullis K, Kennedy IM, Jones AD, Chang DP, Yang G, Kelly P. Dioxinlike properties of a trichloroethylene combustion-generated aerosol. Environmental Health Perspectives. 104: 734-43. PMID 8841759  1
1996 Garrison PM, Tullis K, Aarts JMMJG, Brouwer A, Giesy JP, Denison MS. Species-Specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals Fundamental and Applied Toxicology. 30: 194-203. PMID 8812265 DOI: 10.1006/faat.1996.0056  1
1996 Walsh AA, Tullis K, Rice RH, Denison MS. Identification of a novel cis-acting negative regulatory element affecting expression of the CYP1A1 gene in rat epidermal cells Journal of Biological Chemistry. 271: 22746-22753. PMID 8798449 DOI: 10.1074/jbc.271.37.22746  1
1996 Balaguer P, Joyeux A, Denison MS, Vincent R, Gillesby BE, Zacharewski T. Assessing the estrogenic and dioxin-like activities of chemicals and complex mixtures using in vitro recombinant receptor-reporter gene assays Canadian Journal of Physiology and Pharmacology. 74: 216-222. PMID 8723035 DOI: 10.1139/cjpp-74-2-216  1
1996 Sanderson JT, Aarts JMMJG, Brouwer A, Froese KL, Denison MS, Giesy JP. Comparison of Ah receptor-mediated luciferase and ethoxyresorufin-O-deethylase induction in H4IIE cells: Implications for their use as bioanalytical tools for the detection of polyhalogenated aromatic hydrocarbons Toxicology and Applied Pharmacology. 137: 316-325. PMID 8661358 DOI: 10.1006/taap.1996.0086  1
1996 Kraemer SA, Arthur KA, Denison MS, Smith WL, DeWitt DL. Regulation of prostaglandin endoperoxide H synthase-2 expression by 2,3,7,8,-tetrachlorodibenzo-p-dioxin. Archives of Biochemistry and Biophysics. 330: 319-28. PMID 8660662 DOI: 10.1006/abbi.1996.0259  1
1996 Murk AJ, Legler J, Denison MS, Giesy JP, Van De Guchte C, Brouwer A. Chemical-activated luciferase gene expression (CALUX): A novel in vitro bioassay for Ah receptor active compounds in sediments and pore water Toxicological Sciences. 33: 149-160. DOI: 10.1006/faat.1996.0152  1
1995 Aarts JMMJG, Denison MS, Cox MA, Schalk MAC, Garrison PM, Tullis K, de Haan LHJ, Brouwer A. Species-specific antagonism of Ah receptor action by 2,2′,5,5′-tetrachloro- and 2,2′,3,3′,4,4′-hexachlorobiphenyl European Journal of Pharmacology: Environmental Toxicology And. 293: 463-474. PMID 8748700 DOI: 10.1016/0926-6917(95)90067-5  1
1995 Bank PA, Yao EF, Swanson HI, Tullis K, Denison MS. DNA Binding of the Transformed Guinea Pig Hepatic Ah Receptor Complex: Identification and Partial Characterization of 2 High-Affinity DNA-Binding Forms Archives of Biochemistry and Biophysics. 317: 439-448. PMID 7893161 DOI: 10.1006/abbi.1995.1186  1
1995 Denison MS, Whitlock JP. Xenobiotic-inducible transcription of cytochrome P450 genes Journal of Biological Chemistry. 270: 18175-18178. PMID 7629130 DOI: 10.1074/jbc.270.31.18175  1
1995 Brouwer A, Ahlborg UG, Van den Berg M, Birnbaum LS, Ruud Boersma E, Bosveld B, Denison MS, Earl Gray L, Hagmar L, Holene E, Huisman M, Jacobson SW, Jacobson JL, Koopman-Esseboom C, Koppe JG, et al. Functional aspects of developmental toxicity of polyhalogenated aromatic hydrocarbons in experimental animals and human infants European Journal of Pharmacology: Environmental Toxicology And. 293: 1-40. PMID 7545581 DOI: 10.1016/0926-6917(95)90015-2  1
1995 Newsted JL, Giesy JP, Ankley GT, Tillitt DE, Crawford RA, Gooch JW, Jones PD, Denison MS. Development of toxic equivalency factors for PCB congeners and the assessment of TCDD and PCB mixtures in rainbow trout Environmental Toxicology and Chemistry. 14: 861-871.  1
1994 Dehaan LHJ, Simons JWFA, Bos AT, Aarts JMMJG, Denison MS, Brouwer A. Inhibition of Intercellular Communication by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Dioxin-Like PCBs in Mouse Hepatoma Cells (Hepa1c1c7): Involvement of the Ah Receptor Toxicology and Applied Pharmacology. 129: 283-293. PMID 7992318 DOI: 10.1006/taap.1994.1253  1
1994 El-Fouly MH, Richter C, Giesy JP, Denison MS. Production of a novel recombinant cell line for use as a bioassay system for detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals Environmental Toxicology and Chemistry. 13: 1581-1588.  1
1993 Santostefano M, Merchant M, Arellano L, Morrison V, Denison MS, Safe S. alpha-Naphthoflavone-induced CYP1A1 gene expression and cytosolic aryl hydrocarbon receptor transformation. Molecular Pharmacology. 43: 200-6. PMID 8381508  1
1993 Schafer MW, Madhukar BV, Swanson HI, Tullis K, Denison MS. Protein Kinase C Is Not Involved in Ah Receptor Transformation and DNA Binding Archives of Biochemistry and Biophysics. 307: 267-271. PMID 7506016 DOI: 10.1006/abbi.1993.1589  1
1993 Denison MS. Binding of transformed Ah receptor complex to a dioxin responsive transcriptional enhancer: Evidence for two distinct heteromeric DNA-binding forms Biochemistry®. 12841-12849. DOI: 10.1021/bi00210a037  1
1992 Denison MS. Heterogeneity of rat hepatic Ah receptor: identification of two receptor forms which differ in their biochemical properties Journal of Biochemical Toxicology. 7: 249-256. PMID 1338110  1
1992 Bank PA, Yao EF, Phelps CL, Harper PA, Denison MS. Species-specific binding of transformed Ah receptor to a dioxin responsive transcriptional enhancer European Journal of Pharmacology: Environmental Toxicology And. 228: 85-94. PMID 1332880 DOI: 10.1016/0926-6917(92)90016-6  1
1992 Harper PA, Giannone JV, Okey AB, Denison MS. In vitro transformation of the human Ah receptor and its binding to a dioxin response element Molecular Pharmacology. 42: 603-612. PMID 1331752  1
1992 Yao EF, Denison MS. DNA sequence determinants for binding of transformed Ah receptor to a dioxin-responsive enhancer Biochemistry. 31: 5060-5067. PMID 1318077  1
1992 Denison MS, Bank PA, Yao EF. DNA sequence-specific binding of transformed ah receptor to a dioxin responsive enhancer: Looks aren't everything Chemosphere. 25: 33-36. DOI: 10.1016/0045-6535(92)90473-5  1
1991 Denison MS, Yao EF. Characterization of the interaction of transformed rat hepatic cytosolic Ah receptor with a dioxin responsive transcriptional enhancer Archives of Biochemistry and Biophysics. 284: 158-166. PMID 1846511 DOI: 10.1016/0003-9861(91)90278-Q  1
1991 Helferich WG, Denison MS. Ultraviolet photoproducts of tryptophan can act as dioxin agonists Molecular Pharmacology. 40: 674-678. PMID 1658604  1
1991 Denison MS. The molecular mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons Chemosphere. 23: 1825-1830. DOI: 10.1016/0045-6535(91)90030-H  1
1990 Prokipcak RD, Denison MS, Okey AB. Nuclear Ah receptor from mouse hepatoma cells: Effect of partial proteolysis on relative molecular mass and DNA-binding properties Archives of Biochemistry and Biophysics. 283: 476-483. PMID 2177330 DOI: 10.1016/0003-9861(90)90670-T  1
1990 Fisher JM, Wu L, Denison MS, Whitlock JP. Organization and function of a dioxin-responsive enhancer. The Journal of Biological Chemistry. 265: 9676-81. PMID 2161840  1
1990 Denison MS, Deal RM. The binding of transformed aromatic hydrocarbon (Ah) receptor to its DNA recognition site is not affected by metal depletion Molecular and Cellular Endocrinology. 69: 51-57. PMID 2157617 DOI: 10.1016/0303-7207(90)90088-P  1
1990 Denison MS, Vella LM. The hepatic Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: species differences in subunit dissociation. Archives of Biochemistry and Biophysics. 277: 382-8. PMID 2155580 DOI: 10.1016/0003-9861(90)90594-O  1
1989 Whitlock JP, Denison MS, Durrin LK, Fisher JM, Galeazzi DR, Jones PBC. Regulation of cytochrome p1-450 gene expression in mouse hepatoma cells by 2,3,7,8-tetrachloflodibenzo-p-dioxin Drug Metabolism Reviews. 20: 839-846. PMID 2806081 DOI: 10.3109/03602538909103583  1
1989 Denison MS, Vella LM, Okey AB. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver: lack of sensitivity to alkaline phosphatase when compared with that of glucocorticoid receptor. Archives of Biochemistry and Biophysics. 273: 458-65. PMID 2774562 DOI: 10.1016/0003-9861(89)90505-5  1
1989 Whitlock JP, Denison MS, Fisher JM, Shen ES. Induction of hepatic cytochrome P450 gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Molecular Biology & Medicine. 6: 169-78. PMID 2693891  1
1989 Denison MS, Hamilton JW, Young CM, Wilkinson CF. Nickel and nickel-conjugate metabolism and acute toxicity. Veterinary and Human Toxicology. 31: 498-9. PMID 2603369  1
1989 Denison MS, Fisher JM, Whitlock JP. Protein-DNA interactions at recognition sites for the dioxin-Ah receptor complex. The Journal of Biological Chemistry. 264: 16478-82. PMID 2550446  1
1988 Denison MS, Fisher JM, Whitlock JP. The DNA recognition site for the dioxin-Ah receptor complex. Nucleotide sequence and functional analysis Journal of Biological Chemistry. 263: 17221-17224. PMID 2846558  1
1988 Denison MS, Fisher JM, Whitlock JP. Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer Proceedings of the National Academy of Sciences of the United States of America. 85: 2528-2532. PMID 2833743  1
1987 Denison MS, Vella LM, Okey AB. Structure and function of the Ah receptor: sulfhydryl groups required for binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to cytosolic receptor from rodent livers. Archives of Biochemistry and Biophysics. 252: 388-95. PMID 3028264 DOI: 10.1016/0003-9861(87)90045-2  1
1986 Okey AB, Roberts EA, Harper PA, Denison MS. Induction of drug-metabolizing enzymes: Mechanisms and consequences Clinical Biochemistry. 19: 132-141. PMID 3518989 DOI: 10.1016/S0009-9120(86)80060-1  1
1986 Denison MS, Vella LM, Okey AB. Hepatic Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Partial stabilization by molybdate. The Journal of Biological Chemistry. 261: 10189-95. PMID 3015922  1
1986 Denison MS, Harper PA, Okey AB. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Codistribution of unoccupied receptor with cytosolic marker enzymes during fractionation of mouse liver, rat liver and cultured Hepa-1c1 cells European Journal of Biochemistry. 155: 223-229. PMID 3007122  1
1986 Denison MS, Vella LM, Okey AB. Structure and function of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Species difference in molecular properties of the receptors from mouse and rat hepatic cytosols. The Journal of Biological Chemistry. 261: 3987-95. PMID 3005314  1
1986 Denison MS, Okey AB, Hamilton JW, Bloom SE, Wilkinson CF. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: ontogeny in chick embryo liver. Journal of Biochemical Toxicology. 1: 39-49. PMID 2856072  1
1986 Denison MS, Wilkinson CF, Okey AB. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin: Comparative studies in mammalian and nonmammalian species Chemosphere. 15: 1665-1672. DOI: 10.1016/0045-6535(86)90452-2  1
1985 Denison MS, Chambers JE, Yarbrough JD. Short-term interactions between DDT and endrin accumulation and elimination in mosquitofish (Gambusia affinis) Archives of Environmental Contamination and Toxicology. 14: 315-320. PMID 3839122 DOI: 10.1007/BF01055408  1
1985 Denison MS, Wilkinson CF. Identification of the Ah receptor in selected mammalian species and induction of aryl hydrocarbon hydroxylase. European Journal of Biochemistry / Febs. 147: 429-35. PMID 2982617  1
1985 Denison MS, Yarbrough JD. Binding of insecticides to serum proteins in mosquitofish (Gambusia affinis) Comparative Biochemistry and Physiology. Part C, Comparative. 81: 105-107. PMID 2861033 DOI: 10.1016/0742-8413(85)90098-2  1
1985 Denison MS, Hamilton JW, Wilkinson CF. Comparative studies of aryl hydrocarbon hydroxylase and the Ah receptor in nonmammalian species. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology. 80: 319-24. PMID 2861016 DOI: 10.1016/0742-8413(85)90063-5  1
1985 Okey AB, Vella LM, Denison MS. Physiocochemical characterization of the cytosolic Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) Federation Proceedings. 44: No. 482.  1
1985 Denison MS, Vella LM, Okey AB. Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): Subunit dissociation and inactivation of ligand binding in conditions of high ionic strength Federation Proceedings. 44: No. 6225.  1
1984 Denison MS, Fine J, Wilkinson CF. Protamine sulfate precipitation: a new assay for the Ah receptor. Analytical Biochemistry. 142: 28-36. PMID 6097142 DOI: 10.1016/0003-2697(84)90512-8  1
1984 Hamilton JW, Denison MS, Bloom SE, Wilkinson CF. Ontogeny of the cytosolic TCDD receptor in the chick embryo and neonate Federation Proceedings. 43: no. 1708.  1
1983 Wilkinson CF, Hetnarski K, Denison MS, Guengerich FP. Selectivity of 1-phenylimidazole as a ligand for cytochrome P-450 and as an inhibitor of microsomal oxidation. Biochemical Pharmacology. 32: 997-1003. PMID 6838663 DOI: 10.1016/0006-2952(83)90617-2  1
1983 Denison MS, Wilcox M, Murray M, Wilkinson CF. Induction of hepatic microsomal cytochrome P-450 and associated monooxygenases by pentamethylbenzene in the rat. Biochemical Pharmacology. 32: 2610-1. PMID 6615556 DOI: 10.1016/0006-2952(83)90030-8  1
1983 Hamilton JW, Denison MS, Bloom SE. Development of basal and induced aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity in the chicken embryo in ovo. Proceedings of the National Academy of Sciences of the United States of America. 80: 3372-6. PMID 6407011  1
1981 Denison MS, Chambers JE, Yarbrough JD. Persistent vitellogenin-like protein and binding of DDT in the serum of insecticide-resistant mosquitofish (Gambusia Affinis) Comparative Biochemistry and Physiology. Part C, Comparative. 69: 109-112. PMID 6113078 DOI: 10.1016/0306-4492(81)90108-8  1
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