Paul C. Zamecnik - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
Protein biosynthesis and anti-sense DNA
Website:
http://www.fa.hms.harvard.edu/about-our-faculty/memorial-minutes/z/paul-charles-zamecnik/

163 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Hoagland MB, Keller EB, Zamecnik PC. The mechanism of amino acid activation: the work of Mahlon Hoagland. 1956. The Journal of Biological Chemistry. 284: e7-8. PMID 19785094  1
2008 Zhang S, Metelev V, Tabatadze D, Zamecnik P, Bogdanov A. Near-infrared fluorescent oligodeoxyribonucleotide reporters for sensing NF-κB DNA interactions in vitro Oligonucleotides. 18: 235-243. PMID 18699740 DOI: 10.1089/oli.2008.0135  1
2008 Zhang S, Metelev V, Tabatadze D, Zamecnik PC, Bogdanov A. Fluorescence resonance energy transfer in near-infrared fluorescent oligonucleotide probes for detecting protein-DNA interactions. Proceedings of the National Academy of Sciences of the United States of America. 105: 4156-61. PMID 18337505 DOI: 10.1073/pnas.0800162105  1
2008 Tabatadze D, Zamecnik P, Yanachkov I, Wright G, Pierson K, Zhang S, Bogdanov A, Metelev V. A novel thymidine phosphoramidite synthon for incorporation of internucleoside phosphate linkers during automated oligodeoxynucleotide synthesis Nucleosides, Nucleotides and Nucleic Acids. 27: 157-172. PMID 18205070 DOI: 10.1080/15257770701795938  1
2007 Harth G, Zamecnik PC, Tabatadze D, Pierson K, Horwitz MA. Hairpin extensions enhance the efficacy of mycolyl transferase-specific antisense oligonucleotides targeting Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 7199-204. PMID 17438292 DOI: 10.1073/pnas.0701725104  1
2006 Elmaleh DR, Fischman AJ, Tawakol A, Zhu A, Shoup TM, Hoffmann U, Brownell AL, Zamecnik PC. Detection of inflamed atherosclerotic lesions with diadenosine-5',5'''-P1,P4-tetraphosphate (Ap4A) and positron-emission tomography. Proceedings of the National Academy of Sciences of the United States of America. 103: 15992-6. PMID 17038498 DOI: 10.1073/pnas.0607246103  1
2005 Zamecnik P. From protein synthesis to genetic insertion Annual Review of Biochemistry. 74: 1-28. PMID 15952879 DOI: 10.1146/annurev.biochem.74.050304.091632  1
2004 Zamecnik PC, Raychowdhury MK, Tabatadze DR, Cantiello HF. Reversal of cystic fibrosis phenotype in a cultured Delta508 cystic fibrosis transmembrane conductance regulator cell line by oligonucleotide insertion. Proceedings of the National Academy of Sciences of the United States of America. 101: 8150-5. PMID 15148387 DOI: 10.1073/pnas.0401933101  1
2002 Harth G, Horwitz MA, Tabatadze D, Zamecnik PC. Targeting the Mycobacterium tuberculosis 30/32-kDa mycolyl transferase complex as a therapeutic strategy against tuberculosis: Proof of principle by using antisense technology. Proceedings of the National Academy of Sciences of the United States of America. 99: 15614-9. PMID 12427974 DOI: 10.1073/pnas.242612299  1
2000 Harth G, Zamecnik PC, Tang JY, Tabatadze D, Horwitz MA. Treatment of Mycobacterium tuberculosis with antisense oligonucleotides to glutamine synthetase mRNA inhibits glutamine synthetase activity, formation of the poly-L-glutamate/glutamine cell wall structure, and bacterial replication. Proceedings of the National Academy of Sciences of the United States of America. 97: 418-23. PMID 10618433 DOI: 10.1073/pnas.97.1.418  1
1998 Barker RH, Metelev V, Coakley A, Zamecnik P. Plasmodium falciparum: Effect of chemical structure on efficacy and specificity of antisense oligonucleotides against malaria in vitro Experimental Parasitology. 88: 51-59. PMID 9501848 DOI: 10.1006/expr.1998.4192  1
1998 Elmaleh DR, Narula J, Babich JW, Petrov A, Fischman AJ, Khaw BA, Rapaport E, Zamecnik PC. Rapid noninvasive detection of experimental atherosclerotic lesions with novel 99mTc-labeled diadenosine tetraphosphates. Proceedings of the National Academy of Sciences of the United States of America. 95: 691-5. PMID 9435254 DOI: 10.1073/pnas.95.2.691  1
1997 Zamecnik P. Background of the antisense oligonucleotide approach to chemotherapy Antisense and Nucleic Acid Drug Development. 7: 199-202. PMID 9212910  1
1997 Chan SW, Gallo SJ, Kim BK, Guo MJ, Blackburn GM, Zamecnik PC. P1,P4-dithio-P2,P3-monochloromethylene diadenosine 5',5'''-P1,P4-tetraphosphate: a novel antiplatelet agent. Proceedings of the National Academy of Sciences of the United States of America. 94: 4034-9. PMID 9108100 DOI: 10.1073/pnas.94.8.4034  1
1997 Zamecnik P. Exogenous antisense oligonucleotides - A potential form of gene therapy Faseb Journal. 11: A1118.  1
1996 Levina AS, Metelev VG, Cohen AS, Zamecnik PC. Conjugates of minor groove DNA binders with oligodeoxynucleotides: synthesis and properties. Antisense & Nucleic Acid Drug Development. 6: 75-85. PMID 8843321  1
1996 Rapaport E, Levina A, Metelev V, Zamecnik PC. Antimycobacterial activities of antisense oligodeoxynucleotide phosphorothioates in drug-resistant strains. Proceedings of the National Academy of Sciences of the United States of America. 93: 709-13. PMID 8570621 DOI: 10.1073/pnas.93.2.709  1
1996 Barker RH, Metelev V, Rapaport E, Zamecnik P. Inhibition of Plasmodium falciparum malaria using antisense oligodeoxynucleotides Proceedings of the National Academy of Sciences of the United States of America. 93: 514-518. PMID 8552672 DOI: 10.1073/pnas.93.1.514  1
1994 Zamecnik P, Aghajanian J, Zamecnik M, Goodchild J, Witman G. Electron micrographic studies of transport of oligodeoxynucleotides across eukaryotic cell membranes Proceedings of the National Academy of Sciences of the United States of America. 91: 3156-3160. PMID 8159719  1
1994 Temsamani J, Metelev V, Levina A, Agrawal S, Zamecnik P. Inhibition of in vitro transcription by oligodeoxynucleotides Antisense Research and Development. 4: 279-284. PMID 7734942  1
1993 Lisziewicz J, Sun D, Metelev V, Zamecnik P, Gallo RC, Agrawal S. Long-term treatment of human immunodeficiency virus-infected cells with antisense oligonucleotide phosphorothioates. Proceedings of the National Academy of Sciences of the United States of America. 90: 3860-4. PMID 8483903  1
1993 Nyilas A, Agrawal S, Zamecnik P. Solid phase synthesis of oligonucleotides carrying puromycin at 3′-terminal Bioorganic and Medicinal Chemistry Letters. 3: 1371-1374. DOI: 10.1016/S0960-894X(00)80351-0  1
1992 Zamecnik PC, Kim B, Gao MJ, Taylor G, Blackburn GM. Analogues of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) as potential anti-platelet-aggregation agents. Proceedings of the National Academy of Sciences of the United States of America. 89: 2370-3. PMID 1549600 DOI: 10.1073/pnas.89.6.2370  1
1992 Rapaport E, Misiura K, Agrawal S, Zamecnik P. Antimalarial activities of oligodeoxynucleotide phosphorothioates in chloroquine-resistant Plasmodium falciparum Proceedings of the National Academy of Sciences of the United States of America. 89: 8577-8580. PMID 1528864  1
1992 Lisziewicz J, Sun D, Klotman M, Agrawal S, Zamecnik P, Gallo R. Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: An in vitro model for treatment Proceedings of the National Academy of Sciences of the United States of America. 89: 11209-11213. PMID 1454800  1
1992 Kim BK, Zamecnik P, Taylor G, Guo MJ, Blackburn GM. Antithrombotic effect of beta,beta'-monochloromethylene diadenosine 5',5"'-P1,P4-tetraphosphate. Proceedings of the National Academy of Sciences of the United States of America. 89: 11056-8. PMID 1438314 DOI: 10.1073/pnas.89.22.11056  1
1992 Agrawal S, Tang JY, Sun D, Sarin PS, Zamecnik PC. Synthesis and anti-HIV activity of oligoribonucleotides and their phosphorothioate analogs. Annals of the New York Academy of Sciences. 660: 2-10. PMID 1340121 DOI: 10.1111/j.1749-6632.1992.tb21052.x  1
1991 Goodchild J, Kim B, Zamecnik PC. The clearance and degradation of oligodeoxynucleotides following intravenous injection into rabbits. Antisense Research and Development. 1: 153-60. PMID 1841657  1
1991 Zamecnik PC, Agrawal S. Oligodeoxynucleotide hybridization inhibition of HIV and influenza virus. Nucleic Acids Symposium Series. 127-31. PMID 1841268  1
1990 Leiter JM, Agrawal S, Palese P, Zamecnik PC. Inhibition of influenza virus replication by phosphorothioate oligodeoxynucleotides. Proceedings of the National Academy of Sciences of the United States of America. 87: 3430-4. PMID 2333292 DOI: 10.1073/pnas.87.9.3430  1
1990 Agrawal S, Zamecnik PC. Site specific functionalization of oligonucleotides for attaching two different reporter groups. Nucleic Acids Research. 18: 5419-23. PMID 2216715 DOI: 10.1093/nar/18.18.5419  1
1990 Agrawal S, Mayrand SH, Zamecnik PC, Pederson T. Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides. Proceedings of the National Academy of Sciences of the United States of America. 87: 1401-5. PMID 2154746  1
1989 Agrawal S, Ikeuchi T, Sun D, Sarin PS, Konopka A, Maizel J, Zamecnik PC. Inhibition of human immunodeficiency virus in early infected and chronically infected cells by antisense oligodeoxynucleotides and their phosphorothioate analogues. Proceedings of the National Academy of Sciences of the United States of America. 86: 7790-4. PMID 2682627  1
1989 Rapaport E, Zamecnik PC. Similarities in ATP-binding domain between E. coli tyrosyl-tRNA synthetase and human estrogen receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 3: 2554-5. PMID 2680708  1
1989 Hoagland MB, Zamecnik PC, Stephenson ML. Intermediate reactions in protein biosynthesis. 1957. Biochimica Et Biophysica Acta. 1000: 106-7. PMID 2673355  1
1989 Agrawal S, Goodchild J, Civeira M, Sarin PS, Zamecnik PC. Phosphoramidate, phosphorothioate, and methylphosphonate analogs of oligodeoxynucleotide: Inhibitors of replication of human immunodeficiency virus Nucleosides and Nucleotides. 8: 819-823. DOI: 10.1080/07328318908054221  1
1988 Louie S, Kim BK, Zamecnik P. Diadenosine 5′,5‴-p1,p4 - tetraphosphate, a potential antithrombotic agent Thrombosis Research. 49: 557-565. PMID 3388311 DOI: 10.1016/0049-3848(88)90253-8  1
1988 Cardullo RA, Agrawal S, Flores C, Zamecnik PC, Wolf DE. Detection of nucleic acid hybridization by nonradiative fluorescence resonance energy transfer. Proceedings of the National Academy of Sciences of the United States of America. 85: 8790-4. PMID 3194390  1
1988 Sarin PS, Agrawal S, Civeira MP, Goodchild J, Ikeuchi T, Zamecnik PC. Inhibition of acquired immunodeficiency syndrome virus by oligodeoxynucleoside methylphosphonates. Proceedings of the National Academy of Sciences of the United States of America. 85: 7448-51. PMID 3174646  1
1988 Agrawal S, Goodchild J, Civeira MP, Thornton AH, Sarin PS, Zamecnik PC. Oligodeoxynucleoside phosphoramidates and phosphorothioates as inhibitors of human immunodeficiency virus. Proceedings of the National Academy of Sciences of the United States of America. 85: 7079-83. PMID 3174622  1
1988 Goodchild J, Agrawal S, Civeira MP, Sarin PS, Sun D, Zamecnik PC. Inhibition of human immunodeficiency virus replication by antisense oligodeoxynucleotides. Proceedings of the National Academy of Sciences of the United States of America. 85: 5507-11. PMID 3041414  1
1987 Plesner P, Goodchild J, Kalckar HM, Zamecnik PC. Oligonucleotides with rapid turnover of the phosphate groups occur endogenously in eukaryotic cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 1936-9. PMID 3470767  1
1987 Rapaport E, Remy P, Kleinkauf H, Vater J, Zamecnik PC. Aminoacyl-tRNA synthetases catalyze AMP----ADP----ATP exchange reactions, indicating labile covalent enzyme-amino-acid intermediates. Proceedings of the National Academy of Sciences of the United States of America. 84: 7891-5. PMID 2960970  1
1986 Flodgaard H, Zamecnik PC, Meyers K, Klenow H. Diagnosis of storage pool deficiency by determination of diadenosine 5', 5'''-P1,P4-tetraphosphate in whole blood. Thrombosis Research. 41: 345-51. PMID 3705012 DOI: 10.1016/0049-3848(86)90245-8  1
1986 Zamecnik PC, Goodchild J, Taguchi Y, Sarin PS. Inhibition of replication and expression of human T-cell lymphotropic virus type III in cultured cells by exogenous synthetic oligonucleotides complementary to viral RNA. Proceedings of the National Academy of Sciences of the United States of America. 83: 4143-6. PMID 3012555  1
1985 Kim BK, Chao FC, Leavitt R, Fauci AS, Meyers KM, Zamecnik PC. Diadenosine 5',5'''-p1,p4-tetraphosphate deficiency in blood platelets of the Chédiak-Higashi syndrome. Blood. 66: 735-7. PMID 4027387  1
1985 Rapaport E, Yogeeswaran G, Zamecnik PC, Remy P. Covalent modification of phenylalanyl-tRNA synthetase with phenylalanine during the amino acid activation reaction catalyzed by the enzyme. The Journal of Biological Chemistry. 260: 9509-12. PMID 3848435  1
1985 Baril EF, Coughlin SA, Zamecnik PC. 5',5'''-P1, P4 diadenosine tetraphosphate (Ap4A): a putative initiator of DNA replication. Cancer Investigation. 3: 465-71. PMID 2996723 DOI: 10.3109/07357908509039808  1
1984 Elmaleh DR, Zamecnik PC, Castronovo FP, Strauss HW, Rapaport E. 99mTc-labeled nucleotides as tumor-seeking radiodiagnostic agents. Proceedings of the National Academy of Sciences of the United States of America. 81: 918-21. PMID 6322177  1
1984 Zamecnik P. The machinery of protein synthesis Trends in Biochemical Sciences. 9: 464-466. DOI: 10.1016/0968-0004(84)90308-6  1
1983 Holler E, Holmquist B, Vallee BL, Taneja K, Zamecnik P. Circular dichroism and ordered structure of bisnucleoside oligophosphates and their Zn2+ and Mg2+ complexes Biochemistry. 22: 4924-4933. PMID 6639937 DOI: 10.1021/bi00290a008  1
1983 Baril E, Bonin P, Burstein D, Mara K, Zamecnik P. Resolution of the diadenosine 5',5"'-P1,P4-tetraphosphate binding subunit from a multiprotein form of HeLa cell DNA polymerase alpha. Proceedings of the National Academy of Sciences of the United States of America. 80: 4931-5. PMID 6576366 DOI: 10.1073/pnas.80.16.4931  1
1983 Zamecnik P. Diadenosine 5′,5‴-P1,P4-tetraphosphate (Ap4A): Its role in cellular metabolism Analytical Biochemistry. 134: 1-10. PMID 6318593 DOI: 10.1016/0003-2697(83)90255-5  1
1982 Zamecnik PC, Rapaport E, Baril EF. Priming of DNA synthesis by diadenosine 5',5"'-P1,P4-tetraphosphate with a double-stranded octadecamer as a template and DNA polymerase alpha. Proceedings of the National Academy of Sciences of the United States of America. 79: 1791-4. PMID 6952229  1
1981 Rapaport E, Zamecnik PC, Baril EF. Association of diadenosine 5',5"'-P1,P4-tetraphosphate binding protein with HeLa cell DNA polymerase alpha. The Journal of Biological Chemistry. 256: 12148-51. PMID 7298650  1
1981 Harris NL, Gang DL, Quay SC, Poppema S, Zamecnik PC, Nelson-Rees WA, O'Brien SJ. Contamination of Hodgkin's disease cell cultures. Nature. 289: 228-30. PMID 7192801 DOI: 10.1038/289228a0  1
1981 Siekevitz P, Zamecnik PC. Ribosomes and protein synthesis. The Journal of Cell Biology. 91: 53s-65s. PMID 7033244  1
1981 Rapaport E, Zamecnik PC, Baril EF. HeLa cell DNA polymerase alpha is tightly associated with tryptophanyl-tRNA synthetase and diadenosine 5',5"'-P1,P4-tetraphosphate binding activities. Proceedings of the National Academy of Sciences of the United States of America. 78: 838-42. PMID 6940151  1
1979 Gang DL, Long JC, Zamecnik PC, Chi SY, Dvorak AM. Electron microscopy of Hodgkin's disease tissue cultures. Cancer. 44: 543-57. PMID 476568 DOI: 10.1002/1097-0142(197908)44:2<543::AID-CNCR2820440223>3.0.CO;2-A  1
1979 Zamecnik PC. Historical aspects of protein synthesis. Annals of the New York Academy of Sciences. 325: 268-301. PMID 378072  1
1979 Rapaport E, Garcia-Blanco MA, Zamecnik PC. Regulation of DNA replication in S phase nuclei by ATP and ADP pools. Proceedings of the National Academy of Sciences of the United States of America. 76: 1643-7. PMID 287004  1
1978 Rapaport E, Zamecnik PC. Increased incorporation of adenosine into adenine nucleotide pools in serum-deprived mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 75: 1145-7. PMID 274706  1
1978 Stephenson ML, Zamecnik PC. Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proceedings of the National Academy of Sciences of the United States of America. 75: 285-8. PMID 75546  1
1978 Zamecnik PC, Stephenson ML. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proceedings of the National Academy of Sciences of the United States of America. 75: 280-4. PMID 75545  1
1977 Long JC, Aisenberg AC, Zamecnik PC. Chromatographic and electrophoretic analysis of an antigen in Hodgkin's disease tissue cultures. Journal of the National Cancer Institute. 58: 223-7. PMID 833873  1
1977 Kolodny NH, Neville AC, Coleman DL, Zamecnik PC. Proton magnetic resonance investigation of interactions between L-tryptophan and dinucleoside phosphates at low pD. Biopolymers. 16: 259-75. PMID 831861 DOI: 10.1002/bip.1977.360160204  1
1977 Zamecnik PC, Long JC. Growth of cultured cells from patients with Hodgkin's disease and transplantation into nude mice. Proceedings of the National Academy of Sciences of the United States of America. 74: 754-8. PMID 265539  1
1977 Long JC, Zamecnik PC, Aisenberg AC, Atkins L. Tissue culture studies in Hodgkin's disease: Morphologic, cytogenetic, cell surface, and enzymatic properties of cultures derived from splenic tumors. The Journal of Experimental Medicine. 145: 1484-500. PMID 68093  1
1977 Schwartz DE, Zamecnik PC, Weith HL. Rous sarcoma virus genome is terminally redundant: the 3' sequence. Proceedings of the National Academy of Sciences of the United States of America. 74: 994-8. PMID 66684  1
1976 Rapaport E, Zamecnik PC. Presence of diadenosine 5',5''' -P1, P4-tetraphosphate (Ap4A) in mamalian cells in levels varying widely with proliferative activity of the tissue: a possible positive "pleiotypic activator". Proceedings of the National Academy of Sciences of the United States of America. 73: 3984-8. PMID 1069282  1
1976 Hirshfield IN, Yeh FM, Zamecnik PC. An in vivo effect of the metabolites L-alanine and glycyl-L-leucine on the properties of lysyl-tRNA synthetase from Escherichia coli K-12. I. Influence on subunit composition and molecular weight distribution. Biochimica Et Biophysica Acta. 435: 290-305. PMID 779846 DOI: 10.1016/0005-2787(76)90110-6  1
1976 Rapaport E, Zamecnik PC. Incorporation of adenosine into ATP: formation of compartmentalized ATP. Proceedings of the National Academy of Sciences of the United States of America. 73: 3122-5. PMID 184461  1
1975 Rapaport E, Zamecnik PC. A new chemical procedure for 32P-labeling of ribonucleic acids at their 5'-ends after isolation. Proceedings of the National Academy of Sciences of the United States of America. 72: 314-7. PMID 1090934  1
1975 Heine UI, Weber GH, Cottler-Fox M, Layard MW, Stephenson ML, Zamecnik PC. Analysis of oncornavirus RNA subunits by electron microscopy. Proceedings of the National Academy of Sciences of the United States of America. 72: 3716-20. PMID 171673 DOI: 10.1073/pnas.72.9.3716  1
1975 Rapaport E, Svihovec SK, Zamecnik PC. Relationship of the first step in protein synthesis to ppGpp: formation of A(5')ppp(5')Gpp. Proceedings of the National Academy of Sciences of the United States of America. 72: 2653-7. PMID 170611  1
1974 Zamecnik PC. Joseph Charles Aub 1890-1973. Transactions of the Association of American Physicians. 87: 12-4. PMID 4617362  1
1974 Long JC, Aisenberg AC, Zamecnik PC. An antigen in Hodgkin's disease tissue cultures: fluorescent antibody studies. Proceedings of the National Academy of Sciences of the United States of America. 71: 2285-9. PMID 4601585  1
1974 Long JC, Aisenberg AC, Zamecnik PC. An antigen in Hodgkin's disease tissue cultures: radioiodine-labeled antibody studies. Proceedings of the National Academy of Sciences of the United States of America. 71: 2605-9. PMID 4136520  1
1973 Stephenson ML, Scott JF, Zamecnik PC. Evidence that the polyadenylic acid segment of "35S" RNA of avian myeloblastosis virus is located at the 3'-OH terminus. Biochemical and Biophysical Research Communications. 55: 8-16. PMID 4362664 DOI: 10.1016/S0006-291X(73)80052-X  1
1973 Zamecnik PC, Rosenthal LJ, Randerath K. Minor base changes in transfer ribonucleic acid in avian myeloblastosis virus. Bibliotheca Haematologica. 39: 474-81. PMID 4360179  1
1973 Rosenthal LJ, Zamecnik PC. Amino-acid acceptor activity of the "70S-associated" 4S RNA from avian myeloblastosis virus. Proceedings of the National Academy of Sciences of the United States of America. 70: 1184-5. PMID 4352225  1
1973 Rosenthal LJ, Zamecnik PC. Minor base composition of "70S-associated" 4S RNA from avian myeloblastosis virus. Proceedings of the National Academy of Sciences of the United States of America. 70: 865-9. PMID 4351808  1
1973 Long JC, Aisenberg AC, Zamecnik MV, Zamecnik PC. A tumor antigen in tissue cultures derived from patients with Hodgkin's disease. Proceedings of the National Academy of Sciences of the United States of America. 70: 1540-4. PMID 4351181  1
1972 Hirshfield IN, Tomford JW, Zamecnik PC. Thiosine-resistant mutants of Escherichia coli K-12 with growth-medium-dependent lysyl-tRNA synthetase activity.II. Evidence for an altered lysyl-tRNA synthetase. Biochimica Et Biophysica Acta. 259: 344-56. PMID 4552090 DOI: 10.1016/0005-2787(72)90309-7  1
1972 Hirshfield IN, Zamecnik PC. Thiosine-resistant mutants of Escherichia coli K-12 with growth-medium-dependent lysl-tRNA synthetase activity. I. Isolation and physiological characterization. Biochimica Et Biophysica Acta. 259: 330-43. PMID 4552089 DOI: 10.1016/0005-2787(72)90308-5  1
1972 Stephenson ML, Wirthlin LS, Scott JF, Zamecnik PC. The 3'-terminal nucleosides of the high molecular weight RNA of avian myeloblastosis virus. Proceedings of the National Academy of Sciences of the United States of America. 69: 1176-80. PMID 4338584  1
1971 Zamecnik PC. Summary of symposium on transfer RNA and transfer RNA modification in differentiation and neoplasia. Cancer Research. 31: 716-21. PMID 4932216  1
1971 Randerath K, Rosenthal LJ, Zamecnik PC. Base composition differences between avian myeloblastosis virus transfer RNA and transfer RNA isolated from host cells. Proceedings of the National Academy of Sciences of the United States of America. 68: 3233-7. PMID 4332019  1
1971 Zamecnik PC, Yu CT. [18] Modification of tRNA's by bromination Methods in Enzymology. 20: 175-178. DOI: 10.1016/S0076-6879(71)20020-3  1
1970 Bloemers HP, Stephenson ML, Zamecnik PC. A sensitive micro assay for inorganic pyrophosphatase. Analytical Biochemistry. 34: 66-70. PMID 5440917 DOI: 10.1016/0003-2697(70)90086-2  1
1970 Marshall RD, Zamecnik PC. Aspects of the kinetic properties of lysyl-tRNA synthetase from Escherichia coli, strain B. Biochimica Et Biophysica Acta. 198: 376-85. PMID 4313535 DOI: 10.1016/0005-2744(70)90070-7  1
1969 Scott JF, Zamecnik PC. Some optical properties of diadenosine-5'-phosphates. Proceedings of the National Academy of Sciences of the United States of America. 64: 1308-14. PMID 5271753  1
1969 Zamecnik PC. An historical account of protein synthesis, with current overtones--a personalized view. Cold Spring Harbor Symposia On Quantitative Biology. 34: 1-16. PMID 4909499  1
1969 Marshall RD, Zamecnik PC. Some physical properties of lysyl and arginyl-transfer RNA synthetases of Escherichia coli B. Biochimica Et Biophysica Acta. 181: 454-64. PMID 4893081  1
1968 Schofield P, Zamecnik PC. Cupric ion catalysis in hydrolysis of aminoacyl-tRNA. Biochimica Et Biophysica Acta. 155: 410-6. PMID 4866302  1
1967 Zamecnik MV, Zamecnik PC. Mutation of chloroplasts in Ageratum, following treatment with 5-bromodeoxyuridine. Experimental Cell Research. 45: 218-29. PMID 6022317  1
1967 Haines JA, Zamecnik PC. Chemical modification of aminoacyl ligases and the effect on formation of aminoacyl-tRNA. Biochimica Et Biophysica Acta. 146: 227-38. PMID 4293964  1
1967 Stephenson ML, Zamecnik PC. [89] Partial purification of amino acid specific soluble RNA's by means of a chemical modification of the terminal ribose of sRNA Methods in Enzymology. 12: 670-678.  1
1966 Zamecnik PC. The mechanism of protein synthesis and its possible alteration in the presence of oncogenic RNA viruses. Cancer Research. 26: 1-6. PMID 5901745  1
1966 Zamecnik PC, Stephenson ML, Janeway CM, Randerath K. Enzymatic synthesis of diadenosine tetraphosphate and diadenosine triphosphate with a purified lysyl-sRNA synthetase. Biochemical and Biophysical Research Communications. 24: 91-7. PMID 5338216  0.68
1966 Burton K, Varney NF, Zamecnik PC. Action of osmium tetroxide on amino acid-transfer ribonucleic acid: correlations between the genetic code and the sensitivity of acceptor activity. The Biochemical Journal. 99: 29C-31C. PMID 5337447  1
1966 Sarin PS, Zamecnik PC, Berquist PL, Scott JF. Conformational differences among purified samples of transfer RNA from yeast. Proceedings of the National Academy of Sciences of the United States of America. 55: 579-85. PMID 5221242  1
1966 Randerath K, Janeway CM, Stephenson ML, Zamecnik PC. Isolation and characterization of dinucleoside tetra- and tri-phosphates formed in the presence of lysyl-sRNA synthetase. Biochemical and Biophysical Research Communications. 24: 98-105. PMID 4290754  1
1965 SARIN PS, ZAMECNIK PC. MODIFICATION OF AMINO ACID ACCEPTANCE AND TRANSFER CAPACITY OF RNA IN THE PRESENCE OF ORGANIC SOLVENTS. Biochemical and Biophysical Research Communications. 19: 198-203. PMID 14332443  1
1965 LAMBORG MR, ZAMECNIK PC, LI TK, KAEGI J, VALLEE BL. ANOMALOUS ROTATORY DISPERSION OF SOLUBLE RIBONUCLEIC ACID AND ITS RELATION TO AMINO ACID SYNTHETASE RECOGNITION. Biochemistry. 4: 63-70. PMID 14285246 DOI: 10.1021/bi00877a012  1
1965 Sarin PS, Zamecnik PC. Conformational differences between s-RNA and aminoacyl s-RNA. Biochemical and Biophysical Research Communications. 20: 400-5. PMID 5324054  1
1965 Lamborg MR, Zamecnik PC. Optical rotatory dispersion of E. coli sRNA in the far ultraviolet region. Biochemical and Biophysical Research Communications. 20: 328-33. PMID 5323174  1
1964 SARIN PS, ZAMECNIK PC. ON THE STABILITY OF AMINOACYL-S-RNA TO NUCLEOPHILIC CATALYSIS. Biochimica Et Biophysica Acta. 91: 653-5. PMID 14262456  1
1964 YU CT, ZAMECNIK PC. EFFECT OF BROMINATION ON THE BIOLOGICAL ACTIVITIES OF TRANSFER RNA OF ESCHERICHIA COLI. Science (New York, N.Y.). 144: 856-9. PMID 14149400 DOI: 10.1126/science.144.3620.856  1
1963 YU CT, ZAMECNIK PC. EFFECT OF BROMINATION ON THE AMINO ACID-ACCEPTING ACTIVITIES OF TRANSFER RIBONUCLEIC ACIDS. Biochimica Et Biophysica Acta. 76: 209-22. PMID 14097377  1
1963 ALLEN DW, ZAMECNIK PC. T1 ribonuclease inhibition of polyuridylic acid-stimulated polyphenylalanine synthesis. Biochemical and Biophysical Research Communications. 11: 294-300. PMID 14012114  1
1963 Yu CT, Zamecnik PC. On the aminoacyl-RNA synthetase recognition sites of yeast and E.coli transfer RNA Biochemical and Biophysical Research Communications. 12: 457-463.  1
1962 ZAMECNIK PC. Unsettled questions in the field of protein synthesis. The Biochemical Journal. 85: 257-64. PMID 14003159  1
1962 STEPHENSON ML, ZAMECNIK PC. Isolation of valyl-RNA of a high degree of purity. Biochemical and Biophysical Research Communications. 7: 91-4. PMID 13916930  1
1962 ALLEN DW, ZAMECNIK PC. The effect of puromycin on rabbit reticulocyte ribosomes. Biochimica Et Biophysica Acta. 55: 865-74. PMID 13860529  1
1961 STEPHENSON ML, ZAMECNIK PC. Purification of valine transfer ribonucleic acid by combined chromatographic and chemical procedures. Proceedings of the National Academy of Sciences of the United States of America. 47: 1627-35. PMID 13916931  1
1960 Zamecnik PC, Stephenson ML, Scott JF. PARTIAL PURIFICATION OF SOLUBLE RNA. Proceedings of the National Academy of Sciences of the United States of America. 46: 811-22. PMID 16590676  0.68
1960 ZAMECNIK PC, HECHT LI, STEPHENSON ML. Intermediate reactions in amino acid incorporation in normal and neoplastic tissues. Acta - Unio Internationalis Contra Cancrum. 16: 1121-4. PMID 13846916  1
1960 ZAMECNIK PC, STEPHENSON ML. Partial purification of transfer RNA. Annals of the New York Academy of Sciences. 88: 708-17. PMID 13787801  1
1960 YU CT, ZAMECNIK PC. A hydrolytic procedure for ribonucleosides and its possible application to the sequential degradation of RNA. Biochimica Et Biophysica Acta. 45: 148-54. PMID 13787539 DOI: 10.1016/0006-3002(60)91435-9  1
1960 MONIER R, STEPHENSON ML, ZAMECNIK PC. The preparation and some properties of a low molecular weight ribonucleic acid from baker's yeast. Biochimica Et Biophysica Acta. 43: 1-8. PMID 13772034  1
1960 LAMBORG MR, ZAMECNIK PC. Amino acid incorporation into protein by extracts of E. coli. Biochimica Et Biophysica Acta. 42: 206-11. PMID 13758500  1
1959 Hecht LI, Stephenson ML, Zamecnik PC. BINDING OF AMINO ACIDS TO THE END GROUP OF A SOLUBLE RIBONUCLEIC ACID. Proceedings of the National Academy of Sciences of the United States of America. 45: 505-18. PMID 16590406  0.68
1958 Zamecnik PC, Stephenson ML, Hecht LI. Intermediate Reactions in Amino Acid Incorporation. Proceedings of the National Academy of Sciences of the United States of America. 44: 73-8. PMID 16590175  0.68
1958 HECHT LI, ZAMECNIK PC, STEPHENSON ML, SCOTT JF. Nucleoside tri-phosphates as precursors of ribonucleic acid end groups in a mammalian system. The Journal of Biological Chemistry. 233: 954-63. PMID 13587523  1
1958 HECHT LI, STEPHENSON ML, ZAMECNIK PC. Dependence of amino acid binding to soluble ribonucleic acid on cytidine triphosphate. Biochimica Et Biophysica Acta. 29: 460-1. PMID 13572384  1
1958 HOAGLAND MB, STEPHENSON ML, SCOTT JF, HECHT LI, ZAMECNIK PC. A soluble ribonucleic acid intermediate in protein synthesis. The Journal of Biological Chemistry. 231: 241-57. PMID 13538965  1
1957 HOAGLAND MB, ZAMECNIK PC, SHARON N, LIPMANN F, STULBERG MP, BOYER PD. Oxygen transfer to AMP in the enzymic synthesis of the hydroxamate of tryptophan. Biochimica Et Biophysica Acta. 26: 215-7. PMID 13479488  1
1957 BAKER WH, ZAMECNIK PC, STEPHENSON ML. In vitro incorporation of C14-DL-leucine into normal and leukemic white cells. Blood. 12: 822-8. PMID 13459929  1
1957 HOAGLAND MB, ZAMECNIK PC, STEPHENSON ML. Intermediate reactions in protein biosynthesis. Biochimica Et Biophysica Acta. 24: 215-6. PMID 13426231  1
1956 STEPHENSON ML, THIMANN KV, ZAMECNIK PC. Incorporation of C14-amino acids into proteins of leaf disks and cell-free fractions of tobacco leaves. Archives of Biochemistry and Biophysics. 65: 194-209. PMID 13373418  1
1956 KELLER EB, ZAMECNIK PC. The effect of guanosine diphosphate and triphosphate on the incorporation of labeled amino acids into proteins. The Journal of Biological Chemistry. 221: 45-59. PMID 13345797  1
1956 ZAMECNIK PC, KELLER EB, LITTLEFIELD JW, HOAGLAND MB, LOFTFIELD RB. Mechanism of incorporation of labeled amino acids into protein. Journal of Cellular Physiology. Supplement. 47: 81-101. PMID 13332015  1
1956 HOAGLAND MB, KELLER EB, ZAMECNIK PC. Enzymatic carboxyl activation of amino acids. The Journal of Biological Chemistry. 218: 345-58. PMID 13278342  1
1955 LITTLEFIELD JW, KELLER EB, GROSS J, ZAMECNIK PC. Studies on cytoplasmic ribonucleoprotein particles from the liver of the rat. The Journal of Biological Chemistry. 217: 111-23. PMID 13271375  1
1954 KELLER EB, ZAMECNIK PC, LOFTFIELD RB. The role of microsomes in the incorporation of amino acids into proteins. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 2: 378-86. PMID 13192327  1
1954 ZAMECNIK PC, KELLER EB. Relation between phosphate energy donors and incorporation of labeled amino acids into proteins. The Journal of Biological Chemistry. 209: 337-54. PMID 13192089  1
1952 ZAMECNIK PC. Studies on in vitro metabolism of the rat hepatoma. Texas Reports On Biology and Medicine. 10: 273-8. PMID 14922280  1
1952 ZAMECNIK PC. The biochemistry of neoplastic tissue. Annual Review of Biochemistry. 21: 411-30. PMID 12977112 DOI: 10.1146/annurev.bi.21.070152.002211  1
1951 ZAMECNIK PC, LOFTFIELD RB, STEPHENSON ML, STEELE JM. Studies on the carbohydrate and protein metabolism of the rat hepatoma. Cancer Research. 11: 592-602. PMID 14859222  1
1951 EMERSON WJ, ZAMECNIK PC, NATHANSON IT. The effect of sex hormones on hepatic and renal lesions induced in rats by a choline-deficient diet. Endocrinology. 48: 548-59. PMID 14840414 DOI: 10.1210/endo-48-5-548  1
1950 ZAMECNIK PC, FRANTZ ID. Peptide bond synthesis in normal and malignant tissue. Cold Spring Harbor Symposia On Quantitative Biology. 14: 199-208. PMID 15442913  1
1950 ZAMECNIK PC, AUB JC. Growth. Annual Review of Physiology. 12: 71-100. PMID 15411163 DOI: 10.1146/annurev.ph.12.030150.000443  1
1950 ZAMECNIK PC. The use of labeled amino acids in the study of the protein metabolism of normal and malignant tissues: a review. Cancer Research. 10: 659-67. PMID 14783758  1
1949 ZAMECNIK PC, STEPHENSON ML. A comparison of activators of proteolytic enzymes and peptidases in normal rat livers and hepatomas. Cancer Research. 9: 3-11. PMID 18110406  1
1949 Zamecnik PC, Loftfield RB, Stephenson ML, Williams CM. Biological Synthesis of Radioactive Silk. Science (New York, N.Y.). 109: 624-6. PMID 17792399 DOI: 10.1126/science.109.2843.624  1
1948 ZAMECNIK PC, FRANTZ ID. Incorporation in vitro of radioactive carbon from carboxyl-labeled dl-alanine and glycine into proteins of normal and malignant rat livers. The Journal of Biological Chemistry. 175: 299-314. PMID 18873305  1
1948 FRANTZ ID, ZAMECNIK PC. The effect of dinitrophenol on the incorporation of alanine labeled with radioactive carbon into the proteins of slices of normal and malignant rat liver. The Journal of Biological Chemistry. 174: 773. PMID 18865651  1
1947 ZAMECNIK PC, STEPHENSON ML. A manometric method for determining the kinetics of an enzymatic hydrolysis of peptides. The Journal of Biological Chemistry. 169: 349-57. PMID 20251454  1
1947 Zamecnik PC, Lipmann F. A STUDY OF THE COMPETITION OF LECITHIN AND ANTITOXIN FOR CL. WELCHII LECITHINASE. The Journal of Experimental Medicine. 85: 395-403. PMID 19871624  1
1947 Zamecnik PC, Brewster LE, Lipmann F. A MANOMETRIC METHOD FOR MEASURING THE ACTIVITY OF THE CL. WELCHII LECITHINASE AND A DESCRIPTION OF CERTAIN PROPERTIES OF THIS ENZYME. The Journal of Experimental Medicine. 85: 381-94. PMID 19871623  1
1947 ZAMECNIK PC, STEPHENSON ML. Activity of catheptic enzymes in p-dimethylaminoazobenzene hepatomas. Cancer Research. 7: 326-32. PMID 18909131  1
1947 Krayer O, Aub JC, Nathanson IT, Zamecnik PC. THE INFLUENCE OF ANTITOXIN UPON THE ACTION OF CLOSTRIDIUM OEDEMATIENS TOXIN IN THE HEART-LUNG PREPARATION OF THE DOG. The Journal of Clinical Investigation. 26: 411-5. PMID 16695432 DOI: 10.1172/JCI101823  1
1947 Aub JC, Zamecnik PC, Nathanson IT. PHYSIOLOGIC ACTION OF CLOSTRIDIUM OEDEMATIENS (NOVYI) TOXIN IN DOGS. The Journal of Clinical Investigation. 26: 404-10. PMID 16695431 DOI: 10.1172/JCI101822  1
1947 Zamecnik PC, Nathanson IT, Aub JC. PHYSIOLOGIC ACTION OF CLOSTRIDIUM WELCHII (TYPE A) TOXINS IN DOGS. The Journal of Clinical Investigation. 26: 394-403. PMID 16695430 DOI: 10.1172/JCI101821  1
1945 POPE A, ZAMECNIK PC. The toxic factors in experimental traumatic shock; the toxic influence of the bacterial flora, particularly Clostridium welchii, in exudates of ischemic muscle. The Journal of Clinical Investigation. 24: 856-63. PMID 21010040  1
1945 ZAMECNIK PC, AUB JC. The toxic factors in experimental traumatic shock; chemical and enzymatic properties of muscle exudate. The Journal of Clinical Investigation. 24: 850-5. PMID 21010039  1
1945 Pope A, Zamecnik PC, Aub JC, Brues AM, Dubos RJ, Nathanson IT, Nutt AL. THE TOXIC FACTORS IN EXERIMENTAL TRAUMATIC SHOCK. VI. THE TOXIC INFLUENCE OF THE BACTERIAL FLORA, PARTICULARLY CLOSTRIDIUM WELCHII, IN EXUDATES OF ISCHEMIC MUSCLE. The Journal of Clinical Investigation. 24: 856-63. PMID 16695282 DOI: 10.1172/JCI101672  1
1945 Zamecnik PC, Aub JC, Brues AM, Kety SS, Nathanson IT, Nutt AL, Pope A. THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. V. CHEMICAL AND ENZYMATIC PROPERTIES OF MUSCLE EXUDATE. The Journal of Clinical Investigation. 24: 850-5. PMID 16695281 DOI: 10.1172/JCI101671  1
1945 Aub JC, Brues AM, Kety SS, Nathanson IT, Nutt AL, Pope A, Zamecnik PC. THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. IV. THE EFFECTS OF THE INTRAVENOUS INJECTION OF THE EFFUSION FROM ISCHEMIC MUSCLE. The Journal of Clinical Investigation. 24: 845-9. PMID 16695280 DOI: 10.1172/JCI101670  1
1945 Kety SS, Nathanson IT, Nutt AL, Pope A, Zamecnik PC, Aub JC, Brues AM. THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. III. SHOCK ACCOMPANYING MUSCLE ISCHEMIA AND LOSS OF VASCULAR FLUID. The Journal of Clinical Investigation. 24: 839-44. PMID 16695279 DOI: 10.1172/JCI101669  1
1945 Brues AM, Cohn WE, Kety SS, Nathanson IT, Nutt AL, Tibbetts DM, Zamecnik PC, Aub JC. THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. II. STUDIES ON ELECTROLYTE AND WATER BALANCE IN SHOCK. The Journal of Clinical Investigation. 24: 835-8. PMID 16695278 DOI: 10.1172/JCI101668  1
1945 Nathanson IT, Nutt AL, Pope A, Zamecnik PC, Aub JC, Brues AM, Kety SS. THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. I. PHYSIOLOGIC EFFECTS OF MUSCLE LIGATION IN THE DOG. The Journal of Clinical Investigation. 24: 829-34. PMID 16695277 DOI: 10.1172/JCI101667  1
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