Jonathan T. Butcher, Ph.D. - Publications

Affiliations: 
2004 Georgia Institute of Technology, Atlanta, GA 
Area:
Biomedical Engineering, Mechanical Engineering, Molecular Biology, Cell Biology, General Biophysics, Medical Biophysics

101 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Albert BJ, Butcher JT. Future prospects in the tissue engineering of heart valves: a focus on the role of stem cells. Expert Opinion On Biological Therapy. PMID 37171790 DOI: 10.1080/14712598.2023.2214313  0.34
2023 Wang M, Lin BY, Sun S, Dai C, Long F, Butcher JT. Shear and hydrostatic stress regulate fetal heart valve remodeling through YAP-mediated mechanotransduction. Elife. 12. PMID 37078699 DOI: 10.7554/eLife.83209  0.364
2022 Wu S, Li Y, Zhang C, Tao L, Kuss M, Lim JY, Butcher J, Duan B. Tri-Layered and Gel-Like Nanofibrous Scaffolds with Anisotropic Features for Engineering Heart Valve Leaflets. Advanced Healthcare Materials. e2200053. PMID 35289986 DOI: 10.1002/adhm.202200053  0.313
2022 Vaidya KA, Donnelly MP, Mahmut A, Jang JW, Gee TW, Aibo MI, Bossong R, Hall C, Samb S, Chen J, Butcher JT. Rac1 mediates Cadherin-11 induced cellular pathogenic processes in aortic valve calcification. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 107414. PMID 35074515 DOI: 10.1016/j.carpath.2022.107414  0.346
2021 Farrar EJ, Hiriart E, Mahmut A, Jagla B, Peal DS, Milan DJ, Butcher JT, Puceat M. OCT4-mediated inflammation induces cell reprogramming at the origin of cardiac valve development and calcification. Science Advances. 7: eabf7910. PMID 34739324 DOI: 10.1126/sciadv.abf7910  0.312
2021 Ma N, Cheung DY, Butcher JT. Incorporating nanocrystalline cellulose into a multifunctional hydrogel for heart valve tissue engineering applications. Journal of Biomedical Materials Research. Part A. PMID 34254733 DOI: 10.1002/jbm.a.37267  0.337
2021 Driscoll K, Cruz AD, Butcher JT. Inflammatory and Biomechanical Drivers of Endothelial-Interstitial Interactions in Calcific Aortic Valve Disease. Circulation Research. 128: 1344-1370. PMID 33914601 DOI: 10.1161/CIRCRESAHA.121.318011  0.316
2021 Gee TW, Richards JM, Mahmut A, Butcher JT. Valve endothelial-interstitial interactions drive emergent complex calcific lesion formation in vitro. Biomaterials. 269: 120669. PMID 33482604 DOI: 10.1016/j.biomaterials.2021.120669  0.347
2020 Wu S, Kumar V, Xiao P, Kuss M, Lim JY, Guda C, Butcher J, Duan B. Age related extracellular matrix and interstitial cell phenotype in pulmonary valves. Scientific Reports. 10: 21338. PMID 33288823 DOI: 10.1038/s41598-020-78507-8  0.314
2020 Palumbo MC, Rong LQ, Kim J, Navid P, Sultana R, Butcher J, Redaelli A, Roman MJ, Devereux RB, Girardi LN, Gaudino MFL, Weinsaft JW. Prosthetic aortic graft replacement of the ascending thoracic aorta alters biomechanics of the native descending aorta as assessed by transthoracic echocardiography. Plos One. 15: e0230208. PMID 32163486 DOI: 10.1371/Journal.Pone.0230208  0.351
2020 Gee T, Farrar E, Wang Y, Wu B, Hsu K, Zhou B, Butcher J. NFκB (Nuclear Factor κ-Light-Chain Enhancer of Activated B Cells) Activity Regulates Cell-Type-Specific and Context-Specific Susceptibility to Calcification in the Aortic Valve. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119313248. PMID 31893948 DOI: 10.1161/Atvbaha.119.313248  0.506
2019 Duan B, Xu C, Das S, Chen JM, Butcher JT. Spatial Regulation of Valve Interstitial Cell Phenotypes within Three-Dimensional Micropatterned Hydrogels. Acs Biomaterials Science & Engineering. 5: 1416-1425. PMID 33405617 DOI: 10.1021/acsbiomaterials.8b01280  0.359
2019 Vaidya KA, Donnelly MP, Gee TW, Ibrahim Aibo MA, Byers S, Butcher JT. Induction of aortic valve calcification by celecoxib and its COX-2 independent derivatives is glucocorticoid-dependent. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 46: 107194. PMID 31982687 DOI: 10.1016/J.Carpath.2019.107194  0.39
2019 Kim DH, Beckett JD, Nagpal V, Seman-Senderos MA, Gould RA, Creamer TJ, MacFarlane EG, Chen Y, Bedja D, Butcher JT, Mitzner W, Rouf R, Hata S, Warren DS, Dietz HC. Calpain 9 as a therapeutic target in TGFβ-induced mesenchymal transition and fibrosis. Science Translational Medicine. 11. PMID 31316008 DOI: 10.1126/Scitranslmed.Aau2814  0.36
2019 Stephens CJ, Spector JA, Butcher JT. Biofabrication of thick vascularized neo-pedicle flaps for reconstructive surgery. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 31170376 DOI: 10.1016/J.Trsl.2019.05.003  0.309
2019 Gee TW, Farrar EJ, Zhou B, Butcher JT. Dynamics of NFkB Regulation of Aortic Valve Endothelial Cell Activation and Calcific Susceptibility Structural Heart. 3: 189-189. DOI: 10.1080/24748706.2019.1591099  0.356
2019 Duan B, Xu C, Das S, Chen JM, Butcher JT. Spatial Regulation of Valve Interstitial Cell Phenotypes within Three-Dimensional Micropatterned Hydrogels Acs Biomaterials Science & Engineering. 5: 1416-1425. DOI: 10.1021/Acsbiomaterials.8B01280  0.467
2018 Gould RA, Aziz H, Woods CE, Seman-Senderos MA, Sparks E, Preuss C, Wünnemann F, Bedja D, Moats CR, McClymont SA, Rose R, Sobreira N, Ling H, MacCarrick G, Kumar AA, ... ... Butcher JT, et al. ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm. Nature Genetics. PMID 30455415 DOI: 10.1038/S41588-018-0265-Y  0.438
2018 Yu JK, Sarathchandra P, Chester A, Yacoub M, Brand T, Butcher JT. Cardiac regeneration following cryoinjury in the adult zebrafish targets a maturation-specific biomechanical remodeling program. Scientific Reports. 8: 15661. PMID 30353076 DOI: 10.1038/S41598-018-33994-8  0.353
2018 Lindsey SE, Butcher JT, Vignon-Clementel IE. Cohort-based multiscale analysis of hemodynamic-driven growth and remodeling of the embryonic pharyngeal arch arteries. Development (Cambridge, England). 145. PMID 30333235 DOI: 10.1242/Dev.162578  0.341
2018 Ryvlin J, Lindsey SE, Butcher JT. Systematic Analysis of the Smooth Muscle Wall Phenotype of the Pharyngeal Arch Arteries during their Reorganization into the Great Vessels and its association with Hemodynamics. Anatomical Record (Hoboken, N.J. : 2007). PMID 30312026 DOI: 10.1002/Ar.23942  0.384
2018 Sraeyes S, Pham DH, Gee TW, Hua J, Butcher JT. Monocytes and Macrophages in Heart Valves: Uninvited Guests or Critical Performers? Current Opinion in Biomedical Engineering. 5: 82-89. PMID 30276357 DOI: 10.1016/J.Cobme.2018.02.003  0.396
2018 Butcher JT. The root problem of heart valve engineering. Science Translational Medicine. 10. PMID 29743349 DOI: 10.1126/Scitranslmed.Aat5850  0.382
2018 Richards JM, Kunitake JAMR, Hunt HB, Wnorowski AN, Lin DW, Boskey AL, Donnelly E, Estroff LA, Butcher JT. Crystallinity of Hydroxyapatite Drives Myofibroblastic Activation and Calcification in Aortic Valves. Acta Biomaterialia. PMID 29505892 DOI: 10.1016/J.Actbio.2018.02.024  0.47
2017 Pagnozzi LA, Butcher JT. Mechanotransduction Mechanisms in Mitral Valve Physiology and Disease Pathogenesis. Frontiers in Cardiovascular Medicine. 4: 83. PMID 29312958 DOI: 10.3389/Fcvm.2017.00083  0.498
2017 Wu S, Duan B, Qin X, Butcher JT. Nanofiber-Structured Hydrogel Yarns with pH-Response Capacity and Cardiomyocyte-Drivability for Bio-Microactuator Application. Acta Biomaterialia. PMID 28733255 DOI: 10.1016/J.Actbio.2017.07.023  0.351
2017 Scuderi GJ, Butcher J. Naturally Engineered Maturation of Cardiomyocytes. Frontiers in Cell and Developmental Biology. 5: 50. PMID 28529939 DOI: 10.3389/Fcell.2017.00050  0.384
2017 Yalcin HC, Amindari A, Butcher JT, Althani A, Yacoub M. Heart Function and Hemodynamics Analysis for Zebrafish Embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 28249360 DOI: 10.1002/Dvdy.24497  0.372
2017 Apoorva F, Tian YF, Pierpont TM, Bassen DM, Cerchietti L, Butcher JT, Weiss RS, Singh A. Lymph Node Stiffness Mimicking Hydrogels Regulate Human B Cell Lymphoma Growth and Cell Surface Receptor Expression in a Molecular Subtype-Specific Manner. Journal of Biomedical Materials Research. Part A. PMID 28177577 DOI: 10.1002/Jbm.A.36031  0.314
2017 Wu S, Duan B, Qin X, Butcher JT. Living Nano-Micro Fibrous Woven Fabric/Hydrogel Composite Scaffolds for Heart Valve Engineering. Acta Biomaterialia. PMID 28110071 DOI: 10.1016/J.Actbio.2017.01.051  0.475
2017 Wojciechowska D, Liberski AR, Wilczek P, Butcher J, Scharfschwerdt M, Hijazi Z, Kasprzak J, Pibarot P, Bianco R. The optimal shape of an aortic heart valve replacement – on the road to the consensus Qscience Connect. 2017: 1. DOI: 10.5339/Connect.2017.1  0.435
2016 Bordeleau F, Mason BN, Lollis EM, Mazzola M, Zanotelli MR, Somasegar S, Califano JP, Montague C, LaValley DJ, Huynh J, Mencia-Trinchant N, Negrón Abril YL, Hassane DC, Bonassar LJ, Butcher JT, et al. Matrix stiffening promotes a tumor vasculature phenotype. Proceedings of the National Academy of Sciences of the United States of America. PMID 28034921 DOI: 10.1073/Pnas.1613855114  0.352
2016 Gould R, Bassen DM, Chakrabarti A, Varner JD, Butcher J. Population Heterogeneity in the Epithelial to Mesenchymal Transition Is Controlled by NFAT and Phosphorylated Sp1. Plos Computational Biology. 12: e1005251. PMID 28027307 DOI: 10.1371/Journal.Pcbi.1005251  0.314
2016 Wu B, Wang Y, Xiao F, Butcher JT, Yutzey KE, Zhou B. Developmental Mechanisms of Aortic Valve Malformation and Disease. Annual Review of Physiology. PMID 27959615 DOI: 10.1146/Annurev-Physiol-022516-034001  0.482
2016 Farrar EJ, Pramil V, Richards JM, Mosher CZ, Butcher JT. Valve interstitial cell tensional homeostasis directs calcification and extracellular matrix remodeling processes via RhoA signaling. Biomaterials. 105: 25-37. PMID 27497058 DOI: 10.1016/J.Biomaterials.2016.07.034  0.489
2016 Sung DC, Bowen CJ, Vaidya KA, Zhou J, Chapurin N, Recknagel A, Zhou B, Chen J, Kotlikoff M, Butcher JT. Cadherin-11 Overexpression Induces Extracellular Matrix Remodeling and Calcification in Mature Aortic Valves. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27312222 DOI: 10.1161/Atvbaha.116.307812  0.448
2016 Wu S, Duan B, Liu P, Zhang C, Qin XH, Butcher JT. Fabrication of Aligned Nanofiber Polymer Yarn Networks for Anisotropic Soft Tissue Scaffolds. Acs Applied Materials & Interfaces. PMID 27304080 DOI: 10.1021/Acsami.6B05199  0.427
2016 Kang LH, Armstrong PA, Lee LJ, Duan B, Kang KH, Butcher JT. Optimizing Photo-Encapsulation Viability of Heart Valve Cell Types in 3D Printable Composite Hydrogels. Annals of Biomedical Engineering. PMID 27106636 DOI: 10.1007/S10439-016-1619-1  0.447
2016 Duan B, Yin Z, Hockaday LA, Magin RL, Butcher JT. Active Tissue Stiffness Modulation Controls Valve Interstitial Cell Phenotype and Osteogenic Potential in 3D Culture. Acta Biomaterialia. PMID 26947381 DOI: 10.1016/J.Actbio.2016.03.007  0.405
2016 Jin J, Weinreb RH, Morrison KA, Cheung D, Schole K, Butcher JT, Spector JA. A Three-Dimensional Tissue Engineered Platform to Simulate Various Microvascular Shear Stress Conditions Journal of the American College of Surgeons. 223: e190. DOI: 10.1016/J.Jamcollsurg.2016.08.481  0.303
2015 Gould RA, Yalcin HC, MacKay JL, Sauls K, Norris R, Kumar S, Butcher JT. Cyclic Mechanical Loading Is Essential for Rac1-Mediated Elongation and Remodeling of the Embryonic Mitral Valve. Current Biology : Cb. PMID 26725196 DOI: 10.1016/J.Cub.2015.11.033  0.436
2015 Wang Y, Wu B, Farrar E, Lui W, Lu P, Zhang D, Alfieri CM, Mao K, Chu M, Yang D, Xu D, Rauchman M, Taylor V, Conway SJ, Yutzey KE, ... Butcher JT, et al. Notch-Tnf signalling is required for development and homeostasis of arterial valves. European Heart Journal. PMID 26491108 DOI: 10.1093/Eurheartj/Ehv520  0.365
2015 Levine RA, Hagége AA, Judge DP, Padala M, Dal-Bianco JP, Aikawa E, Beaudoin J, Bischoff J, Bouatia-Naji N, Bruneval P, Butcher JT, Carpentier A, Chaput M, Chester AH, Clusel C, et al. Mitral valve disease-morphology and mechanisms. Nature Reviews. Cardiology. PMID 26483167 DOI: 10.1038/Nrcardio.2015.161  0.452
2015 Bowen CJ, Zhou J, Sung DC, Butcher JT. Cadherin-11 coordinates cellular migration and extracellular matrix remodeling during aortic valve maturation. Developmental Biology. 407: 145-57. PMID 26188246 DOI: 10.1016/J.Ydbio.2015.07.012  0.504
2015 Cheung DY, Duan B, Butcher JT. Current progress in tissue engineering of heart valves: multiscale problems, multiscale solutions. Expert Opinion On Biological Therapy. 1-18. PMID 26027436 DOI: 10.1517/14712598.2015.1051527  0.424
2015 Farrar EJ, Huntley GD, Butcher J. Endothelial-derived oxidative stress drives myofibroblastic activation and calcification of the aortic valve. Plos One. 10: e0123257. PMID 25874717 DOI: 10.1371/Journal.Pone.0123257  0.39
2015 Duan B, Hockaday LA, Das S, Xu C, Butcher JT. Comparison of Mesenchymal Stem Cell Source Differentiation Toward Human Pediatric Aortic Valve Interstitial Cells Within 3D Engineered Matrices. Tissue Engineering. Part C, Methods. PMID 25594437 DOI: 10.1089/Ten.Tec.2014.0589  0.473
2015 Lindsey SE, Menon PG, Kowalski WJ, Shekhar A, Yalcin HC, Nishimura N, Schaffer CB, Butcher JT, Pekkan K. Growth and hemodynamics after early embryonic aortic arch occlusion. Biomechanics and Modeling in Mechanobiology. 14: 735-51. PMID 25416845 DOI: 10.1007/S10237-014-0633-1  0.388
2015 Gregg CL, Recknagel AK, Butcher JT. Micro/nano-computed tomography technology for quantitative dynamic, multi-scale imaging of morphogenesis. Methods in Molecular Biology (Clifton, N.J.). 1189: 47-61. PMID 25245686 DOI: 10.1007/978-1-4939-1164-6_4  0.309
2014 Lindsey SE, Butcher JT, Yalcin HC. Mechanical regulation of cardiac development. Frontiers in Physiology. 5: 318. PMID 25191277 DOI: 10.3389/Fphys.2014.00318  0.37
2014 Chester AH, El-Hamamsy I, Butcher JT, Latif N, Bertazzo S, Yacoub MH. The living aortic valve: From molecules to function. Global Cardiology Science & Practice. 2014: 52-77. PMID 25054122 DOI: 10.5339/Gcsp.2014.11  0.471
2014 Frendl CM, Tucker SM, Khan NA, Esch MB, Kanduru S, Cao TM, García AJ, King MR, Butcher JT. Endothelial retention and phenotype on carbonized cardiovascular implant surfaces. Biomaterials. 35: 7714-23. PMID 24952977 DOI: 10.1016/J.Biomaterials.2014.05.075  0.438
2014 Mahler GJ, Frendl CM, Cao Q, Butcher JT. Effects of shear stress pattern and magnitude on mesenchymal transformation and invasion of aortic valve endothelial cells. Biotechnology and Bioengineering. 111: 2326-37. PMID 24898772 DOI: 10.1002/Bit.25291  0.493
2014 Duan B, Kapetanovic E, Hockaday LA, Butcher JT. Three-dimensional printed trileaflet valve conduits using biological hydrogels and human valve interstitial cells. Acta Biomaterialia. 10: 1836-46. PMID 24334142 DOI: 10.1016/J.Actbio.2013.12.005  0.498
2014 Farrar EJ, Butcher JT. Heterogeneous susceptibility of valve endothelial cells to mesenchymal transformation in response to TNFα. Annals of Biomedical Engineering. 42: 149-61. PMID 23982279 DOI: 10.1007/S10439-013-0894-3  0.434
2014 Duan B, Hockaday LA, Kang KH, Butcher JT. Aortic heart valve tissue regeneration Tissue and Organ Regeneration: Advances in Micro- and Nanotechnology. 645-694. DOI: 10.4032/9789814411684  0.385
2014 Narayanan BA, Duan B, Butcher JT, Mazumder A, Narayanan NK. Abstract 4049: Stromal Wnt/β-catenin antagonism with DKK1 promotes clonal expansion of multiple myeloma is identified using hyaluronic acid based 3D hydrogel Cancer Research. 74: 4049-4049. DOI: 10.1158/1538-7445.Am2014-4049  0.343
2014 Buskohl PR, Butcher JT, Jenkins JT. The influence of external free energy and homeostasis on growth and shape change Journal of the Mechanics and Physics of Solids. 64: 338-350. DOI: 10.1016/J.Jmps.2013.11.012  0.303
2013 Zhou J, Bowen C, Lu G, Knapp Iii C, Recknagel A, Norris RA, Butcher JT. Cadherin-11 expression patterns in heart valves associate with key functions during embryonic cushion formation, valve maturation and calcification. Cells, Tissues, Organs. 198: 300-10. PMID 24356423 DOI: 10.1159/000356762  0.48
2013 Gregg CL, Butcher JT. Translational paradigms in scientific and clinical imaging of cardiac development. Birth Defects Research. Part C, Embryo Today : Reviews. 99: 106-20. PMID 23897595 DOI: 10.1002/Bdrc.21034  0.325
2013 Duan B, Hockaday LA, Kapetanovic E, Kang KH, Butcher JT. Stiffness and adhesivity control aortic valve interstitial cell behavior within hyaluronic acid based hydrogels. Acta Biomaterialia. 9: 7640-50. PMID 23648571 DOI: 10.1016/J.Actbio.2013.04.050  0.416
2013 Kang KH, Hockaday LA, Butcher JT. Quantitative optimization of solid freeform deposition of aqueous hydrogels Biofabrication. 5. PMID 23636927 DOI: 10.1088/1758-5082/5/3/035001  0.36
2013 Richards J, El-Hamamsy I, Chen S, Sarang Z, Sarathchandra P, Yacoub MH, Chester AH, Butcher JT. Side-specific endothelial-dependent regulation of aortic valve calcification: interplay of hemodynamics and nitric oxide signaling. The American Journal of Pathology. 182: 1922-31. PMID 23499458 DOI: 10.1016/J.Ajpath.2013.01.037  0.494
2013 Gould RA, Aboulmouna LM, Varner JD, Butcher JT. Hierarchical approaches for systems modeling in cardiac development. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 5: 289-305. PMID 23463736 DOI: 10.1002/Wsbm.1217  0.363
2013 Mahler GJ, Farrar EJ, Butcher JT. Inflammatory cytokines promote mesenchymal transformation in embryonic and adult valve endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 121-30. PMID 23104848 DOI: 10.1161/Atvbaha.112.300504  0.432
2013 Duan B, Hockaday LA, Kang KH, Butcher JT. 3D bioprinting of heterogeneous aortic valve conduits with alginate/gelatin hydrogels. Journal of Biomedical Materials Research. Part A. 101: 1255-64. PMID 23015540 DOI: 10.1002/Jbm.A.34420  0.484
2012 Gould RA, Sinha R, Aziz H, Rouf R, Dietz HC, Judge DP, Butcher J. Multi-scale biomechanical remodeling in aging and genetic mutant murine mitral valve leaflets: insights into Marfan syndrome. Plos One. 7: e44639. PMID 22984535 DOI: 10.1371/Journal.Pone.0044639  0.403
2012 Hockaday LA, Kang KH, Colangelo NW, Cheung PY, Duan B, Malone E, Wu J, Girardi LN, Bonassar LJ, Lipson H, Chu CC, Butcher JT. Rapid 3D printing of anatomically accurate and mechanically heterogeneous aortic valve hydrogel scaffolds. Biofabrication. 4: 035005. PMID 22914604 DOI: 10.1088/1758-5082/4/3/035005  0.458
2012 Buskohl PR, Sun MJ, Sun ML, Thompson RP, Butcher JT. Serotonin potentiates transforming growth factor-beta3 induced biomechanical remodeling in avian embryonic atrioventricular valves. Plos One. 7: e42527. PMID 22880017 DOI: 10.1371/Journal.Pone.0042527  0.362
2012 Buskohl PR, Jenkins JT, Butcher JT. Computational simulation of hemodynamic-driven growth and remodeling of embryonic atrioventricular valves. Biomechanics and Modeling in Mechanobiology. 11: 1205-17. PMID 22869343 DOI: 10.1007/S10237-012-0424-5  0.412
2012 Bharadwaj KN, Spitz C, Shekhar A, Yalcin HC, Butcher JT. Computational fluid dynamics of developing avian outflow tract heart valves. Annals of Biomedical Engineering. 40: 2212-27. PMID 22535311 DOI: 10.1007/S10439-012-0574-8  0.398
2012 Waxman AS, Kornreich BG, Gould RA, Moïse NS, Butcher JT. Interactions between TGFβ1 and cyclic strain in modulation of myofibroblastic differentiation of canine mitral valve interstitial cells in 3D culture. Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology. 14: 211-21. PMID 22386586 DOI: 10.1016/J.Jvc.2012.02.006  0.39
2012 Richards JM, Farrar EJ, Kornreich BG, Moїse NS, Butcher JT. The mechanobiology of mitral valve function, degeneration, and repair. Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology. 14: 47-58. PMID 22366572 DOI: 10.1016/J.Jvc.2012.01.002  0.48
2012 Gould RA, Chin K, Santisakultarm TP, Dropkin A, Richards JM, Schaffer CB, Butcher JT. Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture. Acta Biomaterialia. 8: 1710-9. PMID 22281945 DOI: 10.1016/J.Actbio.2012.01.006  0.355
2012 Buskohl PR, Gould RA, Butcher JT. Quantification of embryonic atrioventricular valve biomechanics during morphogenesis. Journal of Biomechanics. 45: 895-902. PMID 22169154 DOI: 10.1016/J.Jbiomech.2011.11.032  0.389
2011 Mahler GJ, Butcher JT. Cardiac developmental toxicity. Birth Defects Research. Part C, Embryo Today : Reviews. 93: 291-7. PMID 22271678 DOI: 10.1002/Bdrc.20219  0.312
2011 Mahler GJ, Butcher JT. Inflammatory regulation of valvular remodeling: the good(?), the bad, and the ugly. International Journal of Inflammation. 2011: 721419. PMID 21792386 DOI: 10.4061/2011/721419  0.436
2011 Butcher JT, Mahler GJ, Hockaday LA. Aortic valve disease and treatment: the need for naturally engineered solutions. Advanced Drug Delivery Reviews. 63: 242-68. PMID 21281685 DOI: 10.1016/J.Addr.2011.01.008  0.472
2011 Kim JS, Min J, Recknagel AK, Riccio M, Butcher JT. Quantitative three-dimensional analysis of embryonic chick morphogenesis via microcomputed tomography. Anatomical Record (Hoboken, N.J. : 2007). 294: 1-10. PMID 21207522 DOI: 10.1002/Ar.21336  0.339
2011 Yalcin HC, Shekhar A, McQuinn TC, Butcher JT. Hemodynamic patterning of the avian atrioventricular valve. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 23-35. PMID 21181939 DOI: 10.1002/Dvdy.22512  0.387
2011 Lindsey SE, Butcher JT. The cycle of form and function in cardiac valvulogenesis Aswan Heart Centre Science & Practice Series. 2011: 10. DOI: 10.5339/Ahcsps.2011.10  0.453
2010 Gould RA, Butcher JT. Isolation of valvular endothelial cells. Journal of Visualized Experiments : Jove. PMID 21248687 DOI: 10.3791/2158  0.473
2010 Yalcin HC, Shekhar A, Rane AA, Butcher JT. An ex-ovo chicken embryo culture system suitable for imaging and microsurgery applications. Journal of Visualized Experiments : Jove. PMID 21048670 DOI: 10.3791/2154  0.306
2010 Yalcin HC, Shekhar A, Nishimura N, Rane AA, Schaffer CB, Butcher JT. Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1728-35. PMID 20709864 DOI: 10.1152/Ajpheart.00495.2010  0.335
2010 Chiu YN, Norris RA, Mahler G, Recknagel A, Butcher JT. Transforming growth factor β, bone morphogenetic protein, and vascular endothelial growth factor mediate phenotype maturation and tissue remodeling by embryonic valve progenitor cells: relevance for heart valve tissue engineering. Tissue Engineering. Part A. 16: 3375-83. PMID 20629541 DOI: 10.1089/Ten.Tea.2010.0027  0.489
2010 Hjortnaes J, Butcher J, Figueiredo JL, Riccio M, Kohler RH, Kozloff KM, Weissleder R, Aikawa E. Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation. European Heart Journal. 31: 1975-84. PMID 20601388 DOI: 10.1093/Eurheartj/Ehq237  0.335
2008 Metzler SA, Pregonero CA, Butcher JT, Burgess SC, Warnock JN. Cyclic strain regulates pro-inflammatory protein expression in porcine aortic valve endothelial cells. The Journal of Heart Valve Disease. 17: 571-7; discussion 57. PMID 18980092  0.305
2008 Norris RA, Borg TK, Butcher JT, Baudino TA, Banerjee I, Markwald RR. Neonatal and adult cardiovascular pathophysiological remodeling and repair: Developmental role of periostin Annals of the New York Academy of Sciences. 1123: 30-40. PMID 18375575 DOI: 10.1196/Annals.1420.005  0.403
2008 Butcher JT, Simmons CA, Warnock JN. Mechanobiology of the aortic heart valve. The Journal of Heart Valve Disease. 17: 62-73. PMID 18365571  0.409
2007 Butcher JT, Nerem RM. Valvular endothelial cells and the mechanoregulation of valvular pathology. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 362: 1445-57. PMID 17569641 DOI: 10.1098/Rstb.2007.2127  0.577
2007 Butcher JT, Markwald RR. Valvulogenesis: The moving target Philosophical Transactions of the Royal Society B: Biological Sciences. 362: 1489-1503. PMID 17569640 DOI: 10.1098/Rstb.2007.2130  0.404
2007 Butcher JT, McQuinn TC, Sedmera D, Turner D, Markwald RR. Transitions in early embryonic atrioventricular valvular function correspond with changes in cushion biomechanics that are predictable by tissue composition Circulation Research. 100: 1503-1511. PMID 17478728 DOI: 10.1161/Circresaha.107.148684  0.369
2007 Butcher JT, Norris RA, Hoffman S, Mjaatvedt CH, Markwald RR. Periostin promotes atrioventricular mesenchyme matrix invasion and remodeling mediated by integrin signaling through Rho/PI 3-kinase Developmental Biology. 302: 256-266. PMID 17070513 DOI: 10.1016/J.Ydbio.2006.09.048  0.331
2007 Butcher JT, Sedmera D, Guldberg RE, Markwald RR. Quantitative volumetric analysis of cardiac morphogenesis assessed through micro-computed tomography Developmental Dynamics. 236: 802-809. PMID 17013892 DOI: 10.1002/Dvdy.20962  0.353
2006 Butcher JT, Barrett BC, Nerem RM. Equibiaxial strain stimulates fibroblastic phenotype shift in smooth muscle cells in an engineered tissue model of the aortic wall. Biomaterials. 27: 5252-8. PMID 16806457 DOI: 10.1016/J.Biomaterials.2006.05.040  0.549
2006 Butcher JT, Nerem RM. Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: effects of steady shear stress. Tissue Engineering. 12: 905-15. PMID 16674302 DOI: 10.1089/Ten.2006.12.905  0.634
2006 Butcher JT, Tressel S, Johnson T, Turner D, Sorescu G, Jo H, Nerem RM. Transcriptional profiles of valvular and vascular endothelial cells reveal phenotypic differences: influence of shear stress. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 69-77. PMID 16293796 DOI: 10.1161/01.Atv.0000196624.70507.0D  0.595
2004 Butcher JT, Nerem RM. Porcine aortic valve interstitial cells in three-dimensional culture: comparison of phenotype with aortic smooth muscle cells. The Journal of Heart Valve Disease. 13: 478-85; discussion 4. PMID 15222296  0.588
2004 Butcher JT, Penrod AM, García AJ, Nerem RM. Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1429-34. PMID 15117733 DOI: 10.1161/01.Atv.0000130462.50769.5A  0.625
2004 Butcher J, Nerem R. MICROARRAY ANALYSIS REVEALS PHENOTYPIC DIFFERENCES BETWEEN VALVULAR AND VASCULAR ENDOTHELIAL CELLS IN STATIC AND FLUID FLOW ENVIRONMENTS Cardiovascular Pathology. 13: 124. DOI: 10.1016/J.Carpath.2004.03.375  0.554
2002 Butcher JT, Nerem RM. Morphological differences between aortic and aortic valve endothelial cells in static and fluid flow conditions Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 318-319.  0.623
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