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Darrick T. Balu, Ph.D. - Publications

Affiliations: 
Psychiatry Harvard University, Cambridge, MA, United States 
Area:
Psychopharmacology
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Folorunso OO, Harvey TL, Brown SE, Cruz C, Shahbo E, Ajjawi I, Balu DT. Forebrain Expression of Serine Racemase During Postnatal Development. Neurochemistry International. 104990. PMID 33592203 DOI: 10.1016/j.neuint.2021.104990  0.318
2020 Wolosker H, Balu DT. D-Serine as the gatekeeper of NMDA receptor activity: implications for the pharmacologic management of anxiety disorders. Translational Psychiatry. 10: 184. PMID 32518273 DOI: 10.1038/S41398-020-00870-X  0.339
2020 Takagi S, Puhl MD, Anderson T, Balu DT, Coyle JT. Serine Racemase Expression by Striatal Neurons. Cellular and Molecular Neurobiology. PMID 32445040 DOI: 10.1007/S10571-020-00880-9  0.397
2020 Coyle JT, Balu D, Wolosker H. D-Serine, the Shape-Shifting NMDA Receptor Co-agonist. Neurochemical Research. PMID 32189130 DOI: 10.1007/S11064-020-03014-1  0.314
2019 Balu DT, Pantazopoulos H, Huang CCY, Muszynski K, Harvey TL, Uno Y, Rorabaugh JM, Galloway CR, Botz-Zapp C, Berretta S, Weinshenker D, Coyle JT. Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease. Neurobiology of Disease. 104511. PMID 31212068 DOI: 10.1016/J.Nbd.2019.104511  0.307
2019 Huang CCY, Muszynski KJ, Bolshakov VY, Balu DT. Deletion of Dtnbp1 in mice impairs threat memory consolidation and is associated with enhanced inhibitory drive in the amygdala. Translational Psychiatry. 9: 132. PMID 30967545 DOI: 10.1038/S41398-019-0465-Y  0.443
2018 Keller S, Punzo D, Cuomo M, Affinito O, Coretti L, Sacchi S, Florio E, Lembo F, Carella M, Copetti M, Cocozza S, Balu DT, Errico F, Usiello A, Chiariotti L. DNA methylation landscape of the genes regulating D-serine and D-aspartate metabolism in post-mortem brain from controls and subjects with schizophrenia. Scientific Reports. 8: 10163. PMID 29976992 DOI: 10.1038/S41598-018-28332-X  0.337
2018 Konopaske GT, Balu DT, Presti KT, Chan G, Benes FM, Coyle JT. Dysbindin-1 contributes to prefrontal cortical dendritic arbor pathology in schizophrenia. Schizophrenia Research. PMID 29759351 DOI: 10.1016/J.Schres.2018.04.042  0.326
2018 Coyle JT, Balu DT. The Role of Serine Racemase in the Pathophysiology of Brain Disorders. Advances in Pharmacology (San Diego, Calif.). 82: 35-56. PMID 29413527 DOI: 10.1016/Bs.Apha.2017.10.002  0.436
2018 Li S, Uno Y, Rudolph U, Cobb J, Liu J, Anderson T, Levy D, Balu DT, Coyle JT. Astrocytes in Primary Cultures Express Serine Racemase, Synthesize D-Serine and Acquire A1 Reactive Astrocyte Features. Biochemical Pharmacology. PMID 29305854 DOI: 10.1016/J.Bcp.2017.12.023  0.323
2017 Balu DT, Coyle JT. Altered CREB Binding to Activity-Dependent Genes in Serine Racemase Deficient Mice, a Mouse Model of Schizophrenia. Acs Chemical Neuroscience. PMID 29172439 DOI: 10.1021/Acschemneuro.7B00404  0.433
2017 Balu DT, Presti KT, Huang CCY, Muszynski K, Radzishevsky I, Wolosker H, Guffanti G, Ressler KJ, Coyle JT. Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning. Biological Psychiatry. PMID 29025687 DOI: 10.1016/J.Biopsych.2017.08.012  0.304
2017 Wolosker H, Balu DT, Coyle JT. Astroglial Versus Neuronal D-Serine: Check Your Controls! Trends in Neurosciences. PMID 28756007 DOI: 10.1016/J.Tins.2017.06.010  0.326
2017 Perez EJ, Tapanes SA, Loris ZB, Balu DT, Sick TJ, Coyle JT, Liebl DJ. Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury. The Journal of Clinical Investigation. PMID 28714867 DOI: 10.1172/Jci92300  0.344
2016 Wolosker H, Balu DT, Coyle JT. The Rise and Fall of the d-Serine-Mediated Gliotransmission Hypothesis. Trends in Neurosciences. PMID 27742076 DOI: 10.1016/J.Tins.2016.09.007  0.332
2016 Coyle JT, Balu DT, Puhl MD, Konopaske GT. History of the Concept of Disconnectivity in Schizophrenia. Harvard Review of Psychiatry. 24: 80-6. PMID 26954593 DOI: 10.1097/Hrp.0000000000000102  0.363
2016 Balu DT, Li Y, Takagi S, Presti KT, Ramikie TS, Rook JM, Jones CK, Lindsley CW, Conn PJ, Bolshakov VY, Coyle JT. An mGlu5 Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26741285 DOI: 10.1038/Npp.2016.2  0.464
2015 Ishiwata S, Umino A, Balu DT, Coyle JT, Nishikawa T. Neuronal serine racemase regulates extracellular D-serine levels in the adult mouse hippocampus. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 25782690 DOI: 10.1007/S00702-015-1388-2  0.392
2015 Takagi S, Balu DT, Coyle JT. Subchronic pharmacological and chronic genetic NMDA receptor hypofunction differentially regulate the Akt signaling pathway and Arc expression in juvenile and adult mice. Schizophrenia Research. 162: 216-21. PMID 25592804 DOI: 10.1016/J.Schres.2014.12.034  0.451
2015 Balu DT, Coyle JT. The NMDA receptor 'glycine modulatory site' in schizophrenia: D-serine, glycine, and beyond. Current Opinion in Pharmacology. 20: 109-15. PMID 25540902 DOI: 10.1016/J.Coph.2014.12.004  0.361
2014 Balu DT, Coyle JT. Chronic D-serine reverses arc expression and partially rescues dendritic abnormalities in a mouse model of NMDA receptor hypofunction. Neurochemistry International. 75: 76-8. PMID 24915645 DOI: 10.1016/J.Neuint.2014.05.015  0.43
2014 Balu DT, Takagi S, Puhl MD, Benneyworth MA, Coyle JT. D-serine and serine racemase are localized to neurons in the adult mouse and human forebrain. Cellular and Molecular Neurobiology. 34: 419-35. PMID 24436034 DOI: 10.1007/S10571-014-0027-Z  0.35
2014 Santini MA, Balu DT, Puhl MD, Hill-Smith TE, Berg AR, Lucki I, Mikkelsen JD, Coyle JT. D-serine deficiency attenuates the behavioral and cellular effects induced by the hallucinogenic 5-HT(2A) receptor agonist DOI. Behavioural Brain Research. 259: 242-6. PMID 24269270 DOI: 10.1016/J.Bbr.2013.11.022  0.627
2014 Balu DT, Takagi S, Bartolomé J, Steckler T, Jones C, Conn PJ, Coyle J. Poster #M8 POSITIVE ALLOSTERIC MODULATION OF MGLUR5 REVERSES THE AKT SIGNALING DEFICITS IN SERINE RACEMASE KNOCKOUT MICE, A GENETIC MODEL OF SCHIZOPHRENIA DUE TO NMDA RECEPTOR HYPOFUNCTION Schizophrenia Research. 153: S191-S192. DOI: 10.1016/S0920-9964(14)70558-4  0.361
2013 Balu DT, Li Y, Puhl MD, Benneyworth MA, Basu AC, Takagi S, Bolshakov VY, Coyle JT. Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction. Proceedings of the National Academy of Sciences of the United States of America. 110: E2400-9. PMID 23729812 DOI: 10.1073/Pnas.1304308110  0.461
2013 Balu DT, Turner JR, Brookshire BR, Hill-Smith TE, Blendy JA, Lucki I. Brain monoamines and antidepressant-like responses in MRL/MpJ versus C57BL/6J mice. Neuropharmacology. 67: 503-10. PMID 23220293 DOI: 10.1016/J.Neuropharm.2012.11.027  0.704
2012 Coyle JT, Basu A, Benneyworth M, Balu D, Konopaske G. Glutamatergic synaptic dysregulation in schizophrenia: therapeutic implications. Handbook of Experimental Pharmacology. 267-95. PMID 23027419 DOI: 10.1007/978-3-642-25758-2_10  0.344
2012 Balu DT, Coyle JT. Neuronal D-serine regulates dendritic architecture in the somatosensory cortex. Neuroscience Letters. 517: 77-81. PMID 22521586 DOI: 10.1016/J.Neulet.2012.04.020  0.385
2012 Balu DT, Basu AC, Corradi JP, Cacace AM, Coyle JT. The NMDA receptor co-agonists, D-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex. Neurobiology of Disease. 45: 671-82. PMID 22024716 DOI: 10.1016/J.Nbd.2011.10.006  0.462
2012 Ho N, Balu DT, Hilario MR, Blendy JA, Lucki I. Depressive phenotypes evoked by experimental diabetes are reversed by insulin. Physiology & Behavior. 105: 702-8. PMID 21945451 DOI: 10.1016/J.Physbeh.2011.09.003  0.622
2012 Balu DT, Carlson GC, Talbot K, Kazi H, Hill-Smith TE, Easton RM, Birnbaum MJ, Lucki I. Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function. Hippocampus. 22: 230-40. PMID 21049487 DOI: 10.1002/Hipo.20887  0.597
2011 Balu DT, Coyle JT. Glutamate receptor composition of the post-synaptic density is altered in genetic mouse models of NMDA receptor hypo- and hyperfunction. Brain Research. 1392: 1-7. PMID 21443867 DOI: 10.1016/J.Brainres.2011.03.051  0.398
2011 DeVito LM, Balu DT, Kanter BR, Lykken C, Basu AC, Coyle JT, Eichenbaum H. Serine racemase deletion disrupts memory for order and alters cortical dendritic morphology. Genes, Brain, and Behavior. 10: 210-22. PMID 21029376 DOI: 10.1111/J.1601-183X.2010.00656.X  0.403
2011 Balu DT, Coyle JT. Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia. Neuroscience and Biobehavioral Reviews. 35: 848-70. PMID 20951727 DOI: 10.1016/J.Neubiorev.2010.10.005  0.327
2010 Balu DT. Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of acute and chronic antidepressant treatments. Experimental and Clinical Psychopharmacology. 18: 71-7. PMID 20158296 DOI: 10.1037/A0017295  0.527
2009 Balu DT, Hodes GE, Anderson BT, Lucki I. Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of chronic antidepressant treatments. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1764-73. PMID 19177066 DOI: 10.1038/Npp.2008.234  0.737
2009 Balu DT, Hodes GE, Hill TE, Ho N, Rahman Z, Bender CN, Ring RH, Dwyer JM, Rosenzweig-Lipson S, Hughes ZA, Schechter LE, Lucki I. Flow cytometric analysis of BrdU incorporation as a high-throughput method for measuring adult neurogenesis in the mouse. Journal of Pharmacological and Toxicological Methods. 59: 100-7. PMID 19121403 DOI: 10.1016/J.Vascn.2008.12.002  0.703
2009 Balu DT, Lucki I. Adult hippocampal neurogenesis: regulation, functional implications, and contribution to disease pathology. Neuroscience and Biobehavioral Reviews. 33: 232-52. PMID 18786562 DOI: 10.1016/J.Neubiorev.2008.08.007  0.576
2008 Balu DT, Hoshaw BA, Malberg JE, Rosenzweig-Lipson S, Schechter LE, Lucki I. Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments. Brain Research. 1211: 37-43. PMID 18433734 DOI: 10.1016/J.Brainres.2008.03.023  0.666
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