James H. Naismith, BSc PhD FRS FRSE FMedSci - Publications

Affiliations: 
1995- BSRC St Andrews University, Scotland, Saint Andrews, Scotland, United Kingdom 
Area:
Structural biology
Website:
https://scholar.google.com/citations?user=fLmKKQMAAAAJ

230 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Moynié L, Milenkovic S, Mislin GLA, Gasser V, Malloci G, Baco E, McCaughan RP, Page MGP, Schalk IJ, Ceccarelli M, Naismith JH. The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model. Nature Communications. 10: 3673. PMID 31413254 DOI: 10.1038/s41467-019-11508-y  1
2019 Harrison PJ, Gable K, Somashekarappa N, Kelly V, Clarke DJ, Naismith JH, Dunn TM, Campopiano DJ. Erratum: Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase. Journal of Lipid Research. 60: 1489. PMID 31371643 DOI: 10.1194/jlr.ERR119000228  1
2019 Yang T, Zhang J, Ke D, Yang W, Tang M, Jiang J, Cheng G, Li J, Cheng W, Wei Y, Li Q, Naismith JH, Zhu X. Hydrophobic recognition allows the glycosyltransferase UGT76G1 to catalyze its substrate in two orientations. Nature Communications. 10: 3214. PMID 31324778 DOI: 10.1038/s41467-019-11154-4  1
2019 Ge Y, Czekster CM, Miller OK, Botting CH, Schwarz-Linek U, Naismith JH. Insights into the mechanism of the cyanobactin heterocyclase enzyme. Biochemistry. PMID 30912640 DOI: 10.1021/acs.biochem.9b00084  1
2019 Scorciapino MA, Malloci G, Serra I, Milenkovic S, Moynié L, Naismith JH, Desarbre E, Page MGP, Ceccarelli M. Complexes formed by the siderophore-based monosulfactam antibiotic BAL30072 and their interaction with the outer membrane receptor PiuA of P. aeruginosa. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. PMID 30635814 DOI: 10.1007/s10534-018-00166-0  1
2018 Moynié L, Serra I, Scorciapino MA, Oueis E, Page MG, Ceccarelli M, Naismith JH. Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogen . Elife. 7. PMID 30558715 DOI: 10.7554/eLife.42270  1
2018 Gao S, Ge Y, Bent AF, Schwarz-Linek U, Naismith JH. Oxidation of cyanobactin precursor peptide is independent of leader peptide and operates in a defined order. Biochemistry. PMID 30208270 DOI: 10.1021/acs.biochem.8b00835  1
2018 Perraud Q, Moynie L, Gasser V, Munier M, Godet J, Hoegy F, Mély Y, Mislin GLA, Naismith JH, Schalk IJ. A key role for the periplasmic PfeE esterase in iron acquisition via the siderophore Enterobactin in Pseudomonas aeruginosa. Acs Chemical Biology. PMID 30086222 DOI: 10.1021/acschembio.8b00543  1
2018 Acosta-Gutierrez S, Ferrara L, Pathania M, Masi M, Wang J, Bodrenko I, Zahn M, Winterhalter M, Stavenger RA, Pages JM, Naismith JH, van den Berg B, Page M, Ceccarelli M. Getting drugs into Gram-negative bacteria: Rational rules for permeation through general porins. Acs Infectious Diseases. PMID 29962203 DOI: 10.1021/acsinfecdis.8b00108  1
2018 Liston SD, McMahon SA, Le Bas A, Suits MDL, Naismith JH, Whitfield C. Periplasmic depolymerase provides insight into ABC transporter-dependent secretion of bacterial capsular polysaccharides. Proceedings of the National Academy of Sciences of the United States of America. PMID 29735649 DOI: 10.1073/pnas.1801336115  1
2018 Ronan JL, Kadi N, McMahon SA, Naismith JH, Alkhalaf LM, Challis GL. Desferrioxamine biosynthesis: diverse hydroxamate assembly by substrate-tolerant acyl transferase DesC. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29685972 DOI: 10.1098/rstb.2017.0068  1
2018 Luscher A, Moynié L, Saint Auguste P, Bumann D, Mazza L, Pletzer D, Naismith JH, Köhler T. The TonB-receptor repertoire offor the uptake of siderophore-drug conjugates. Antimicrobial Agents and Chemotherapy. PMID 29555629 DOI: 10.1128/AAC.00097-18  1
2018 Ludewig H, Czekster CM, Oueis E, Munday ES, Arshad M, Synowsky SA, Bent AF, Naismith JH. Characterization of the fast and promiscuous macrocyclase from plant PCY1 enables the use of simple substrates. Acs Chemical Biology. PMID 29377663 DOI: 10.1021/acschembio.8b00050  1
2017 Ojo OS, Nardone B, Musolino SF, Neal AR, Wilson L, Lebl T, Slawin AMZ, Cordes DB, Taylor JE, Naismith JH, Smith AD, Westwood NJ. Synthesis of the natural product descurainolide and cyclic peptides from lignin-derived aromatics. Organic & Biomolecular Chemistry. PMID 29242868 DOI: 10.1039/c7ob02697h  1
2017 Ackermann K, Pliotas C, Valera S, Naismith JH, Bode BE. Sparse Labeling PELDOR Spectroscopy on Multimeric Mechanosensitive Membrane Channels. Biophysical Journal. 113: 1968-1978. PMID 29117521 DOI: 10.1016/j.bpj.2017.09.005  1
2017 Czekster CM, Ludewig H, McMahon SA, Naismith JH. Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates. Nature Communications. 8: 1045. PMID 29051530 DOI: 10.1038/s41467-017-00862-4  1
2017 Barski M, Brennan B, Miller OK, Potter JA, Vijayakrishnan S, Bhella D, Naismith JH, Elliott RM, Schwarz-Linek U. Rift Valley fever phlebovirus NSs protein core domain structure suggests molecular basis for nuclear filaments. Elife. 6. PMID 28915104 DOI: 10.7554/eLife.29236  1
2017 Michailidou F, Chung CW, Brown MJB, Bent AF, Naismith JH, Leavens WJ, Lynn SM, Sharma SV, Goss RJM. Short and Sweet: Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3'- Deoxy Nucleoside of Pacidamycins. Angewandte Chemie (International Ed. in English). PMID 28786545 DOI: 10.1002/anie.201705639  1
2017 Pliotas C, Grayer SC, Ekkerman S, Chan AK, Healy J, Marius P, Bartlett W, Khan A, Cortopassi WA, Chandler SA, Rasmussen T, Benesch JL, Paton RS, Claridge TDW, Miller S, ... ... Naismith JH, et al. AMP binding stabilizes the KTN domain of the Shewanella denitrificans Kef potassium efflux system. Biochemistry. PMID 28656748 DOI: 10.1021/acs.biochem.7b00300  1
2017 Wang M, Moynié L, Harrison PJ, Kelly V, Piper A, Naismith JH, Campopiano DJ. Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters. Nature Chemical Biology. PMID 28414710 DOI: 10.1038/nchembio.2361  1
2017 Czekster CM, Naismith JH. Kinetic landscape of a peptide-bond-forming prolyl oligopeptidase. Biochemistry. PMID 28332820 DOI: 10.1021/acs.biochem.7b00012  1
2017 Burkhart BJ, Schwalen CJ, Mann G, Naismith JH, Mitchell DA. YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function. Chemical Reviews. PMID 28256131 DOI: 10.1021/acs.chemrev.6b00623  1
2017 Oueis E, Nardone B, Jaspars M, Westwood NJ, Naismith JH. Synthesis of Hybrid Cyclopeptides through Enzymatic Macrocyclization. Chemistryopen. 6: 11-14. PMID 28168143 DOI: 10.1002/open.201600134  1
2017 Moynié L, Luscher A, Rolo D, Pletzer D, Tortajada A, Weingart H, Braun Y, Page MG, Naismith JH, Köhler T. Structure and function of the PiuA and PirA siderophore-drug receptors from Pseudomonas aeruginosa and Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy. PMID 28137795 DOI: 10.1128/AAC.02531-16  1
2017 Stroek R, Ge Y, Talbot PD, Glok MK, Bernas KE, Thomson CM, Gould ER, Alphey MS, Liu H, Florence GJ, Naismith JH, da Silva RG. Kinetics and structure of a cold-adapted hetero-octameric ATP phosphoribosyltransferase. Biochemistry. PMID 28092443 DOI: 10.1021/acs.biochem.6b01138  1
2016 Pliotas C, Naismith JH. Spectator no more, the role of the membrane in regulating ion channel function. Current Opinion in Structural Biology. 45: 59-66. PMID 27940346 DOI: 10.1016/j.sbi.2016.10.017  1
2016 Bent AF, Mann G, Houssen WE, Mykhaylyk V, Duman R, Thomas L, Jaspars M, Wagner A, Naismith JH. Structure of the cyanobactin oxidase ThcOx from Cyanothece sp. PCC 7425, the first structure to be solved at Diamond Light Source beamline I23 by means of S-SAD. Acta Crystallographica. Section D, Structural Biology. 72: 1174-1180. PMID 27841750 DOI: 10.1107/S2059798316015850  1
2016 Ferrara LG, Wallat GD, Moynié L, Dhanasekar NN, Aliouane S, Acosta-Gutiérrez S, Pagès JM, Bolla JM, Winterhalter M, Ceccarelli M, Naismith JH. MOMP from Campylobacter jejuni is a trimer of 18 stranded β-barrel monomers with a Ca(2+) ion bound at the constriction zone. Journal of Molecular Biology. PMID 27693650 DOI: 10.1016/j.jmb.2016.09.021  1
2016 Czekster CM, Ge Y, Naismith JH. Mechanisms of cyanobactin biosynthesis. Current Opinion in Chemical Biology. 35: 80-88. PMID 27639115 DOI: 10.1016/j.cbpa.2016.08.029  1
2016 Oueis E, Jaspars M, Westwood NJ, Naismith JH. Enzymatic Macrocyclization of 1,2,3-Triazole Peptide Mimetics. Angewandte Chemie (Weinheim An Der Bergstrasse, Germany). 128: 5936-5939. PMID 27397939 DOI: 10.1002/ange.201601564  1
2016 Brás NF, Ferreira P, Calixto AR, Jaspars M, Houssen W, Naismith JH, Fernandes PA, Ramos MJ. The Catalytic Mechanism of the Marine-Derived Macrocyclase PatGmac. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27389424 DOI: 10.1002/chem.201601670  1
2016 Yang J, Wang Y, Wang T, Jiang J, Botting CH, Liu H, Chen Q, Yang J, Naismith JH, Zhu X, Chen L. Pironetin reacts covalently with cysteine-316 of α-tubulin to destabilize microtubule. Nature Communications. 7: 12103. PMID 27357539 DOI: 10.1038/ncomms12103  1
2016 Oueis E, Jaspars M, Westwood NJ, Naismith JH. Enzymatic Macrocyclization of 1,2,3-Triazole Peptide Mimetics. Angewandte Chemie (International Ed. in English). PMID 27059105 DOI: 10.1002/anie.201601564  1
2016 Constantinescu-Aruxandei D, Petrovic-Stojanovska B, Penedo JC, White MF, Naismith JH. Mechanism of DNA loading by the DNA repair helicase XPD. Nucleic Acids Research. PMID 26896802 DOI: 10.1093/nar/gkw102  1
2016 Valera S, Ackermann K, Pliotas C, Huang H, Naismith JH, Bode BE. Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26865468 DOI: 10.1002/chem.201505143  1
2015 Constantinescu-Aruxandei D, Petrovic-Stojanovska B, Schiemann O, Naismith JH, White MF. Taking a molecular motor for a spin: helicase mechanism studied by spin labeling and PELDOR. Nucleic Acids Research. PMID 26657627 DOI: 10.1093/nar/gkv1373  1
2015 Bajaj H, Scorciapino MA, Moynié L, Page MG, Naismith JH, Ceccarelli M, Winterhalter M. Molecular Basis of Filtering Carbapenems by Porins from β-Lactam-resistant Clinical Strains of Escherichia coli. The Journal of Biological Chemistry. PMID 26645688 DOI: 10.1074/jbc.M115.690156  1
2015 Thompson S, McMahon SA, Naismith JH, O'Hagan D. Exploration of a potential difluoromethyl-nucleoside substrate with the fluorinase enzyme. Bioorganic Chemistry. 64: 37-41. PMID 26642178 DOI: 10.1016/j.bioorg.2015.11.003  1
2015 Moynié L, Hope AG, Finzel K, Schmidberger J, Leckie SM, Schneider G, Burkart MD, Smith AD, Gray DW, Naismith JH. A substrate mimic allows high throughput assay of the FabA protein and consequently the identification of a novel inhibitor of Pseudomonas aeruginosa FabA. Journal of Molecular Biology. PMID 26562505 DOI: 10.1016/j.jmb.2015.10.027  1
2015 Pliotas C, Dahl AC, Rasmussen T, Mahendran KR, Smith TK, Marius P, Gault J, Banda T, Rasmussen A, Miller S, Robinson CV, Bayley H, Sansom MS, Booth IR, Naismith JH. The role of lipids in mechanosensation. Nature Structural & Molecular Biology. PMID 26551077 DOI: 10.1038/nsmb.3120  1
2015 Oueis E, Mann G, Ludwig H, Adamson C, Redpath P, Migaud M, Westwood N, Naismith JH. Derivatisable cyanobactin analogues: a semi-synthetic approach. Chembiochem : a European Journal of Chemical Biology. PMID 26507241 DOI: 10.1002/cbic.201500494  1
2015 Branigan E, Plechanovová A, Jaffray EG, Naismith JH, Hay RT. Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chains. Nature Structural & Molecular Biology. 22: 597-602. PMID 26148049 DOI: 10.1038/nsmb.3052  1
2015 Koehnke J, Mann G, Bent AF, Ludewig H, Shirran S, Botting C, Lebl T, Houssen WE, Jaspars M, Naismith JH. Structural analysis of leader peptide binding enables leader-free cyanobactin processing. Nature Chemical Biology. 11: 558-63. PMID 26098679 DOI: 10.1038/nchembio.1841  1
2015 Juárez JF, Liu H, Zamarro MT, McMahon S, Liu H, Naismith JH, Eberlein C, Boll M, Carmona M, Díaz E. Unraveling the specific regulation of the central pathway for anaerobic degradation of 3-methylbenzoate. The Journal of Biological Chemistry. 290: 12165-83. PMID 25795774 DOI: 10.1074/jbc.M115.637074  1
2015 Hagelueken G, Clarke BR, Huang H, Tuukkanen A, Danciu I, Svergun DI, Hussain R, Liu H, Whitfield C, Naismith JH. A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide. Nature Structural & Molecular Biology. 22: 50-6. PMID 25504321 DOI: 10.1038/nsmb.2935  1
2015 Hagelueken G, Clarke BR, Huang H, Tuukkanen A, Danciu I, Svergun DI, Hussain R, Liu H, Whitfield C, Naismith JH. A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide Nature Structural and Molecular Biology. 22: 50-56. DOI: 10.1038/nsmb.2935  1
2014 Mann G, Koehnke J, Bent AF, Graham R, Houssen W, Jaspars M, Schwarz-Linek U, Naismith JH. The structure of the cyanobactin domain of unknown function from PatG in the patellamide gene cluster. Acta Crystallographica. Section F, Structural Biology Communications. 70: 1597-603. PMID 25484206 DOI: 10.1107/S2053230X1402425X  1
2014 Naismith JH, Parker EJ. Editorial overview: Catalysis and regulation: enzyme catalysis, biosynthetic pathways and regulation. Current Opinion in Structural Biology. 29: iv-v. PMID 25480465 DOI: 10.1016/j.sbi.2014.11.004  1
2014 Koehnke J, Bent AF, Houssen WE, Mann G, Jaspars M, Naismith JH. The structural biology of patellamide biosynthesis. Current Opinion in Structural Biology. 29: 112-21. PMID 25460274 DOI: 10.1016/j.sbi.2014.10.006  1
2014 Houssen WE, Bent AF, McEwan AR, Pieiller N, Tabudravu J, Koehnke J, Mann G, Adaba RI, Thomas L, Hawas UW, Liu H, Schwarz-Linek U, Smith MC, Naismith JH, Jaspars M. An efficient method for the in vitro production of azol(in)e-based cyclic peptides. Angewandte Chemie (International Ed. in English). 53: 14171-4. PMID 25331823 DOI: 10.1002/anie.201408082  1
2014 Thompson S, Zhang Q, Onega M, McMahon S, Fleming I, Ashworth S, Naismith JH, Passchier J, O'Hagan D. A localized tolerance in the substrate specificity of the fluorinase enzyme enables "last-step" 18F fluorination of a RGD peptide under ambient aqueous conditions. Angewandte Chemie (International Ed. in English). 53: 8913-8. PMID 24989327 DOI: 10.1002/anie.201403345  1
2014 Nickerson NN, Mainprize IL, Hampton L, Jones ML, Naismith JH, Whitfield C. Trapped translocation intermediates establish the route for export of capsular polysaccharides across Escherichia coli outer membranes. Proceedings of the National Academy of Sciences of the United States of America. 111: 8203-8. PMID 24843147 DOI: 10.1073/pnas.1400341111  1
2014 Ward R, Pliotas C, Branigan E, Hacker C, Rasmussen A, Hagelueken G, Booth IR, Miller S, Lucocq J, Naismith JH, Schiemann O. Probing the structure of the mechanosensitive channel of small conductance in lipid bilayers with pulsed electron-electron double resonance. Biophysical Journal. 106: 834-42. PMID 24559986 DOI: 10.1016/j.bpj.2014.01.008  1
2014 Kassaar O, McMahon SA, Thompson R, Botting CH, Naismith JH, Stewart AJ. Crystal structure of histidine-rich glycoprotein N2 domain reveals redox activity at an interdomain disulfide bridge: implications for angiogenic regulation. Blood. 123: 1948-55. PMID 24501222 DOI: 10.1182/blood-2013-11-535963  1
2014 Deng H, Ma L, Bandaranayaka N, Qin Z, Mann G, Kyeremeh K, Yu Y, Shepherd T, Naismith JH, O'Hagan D. Identification of fluorinases from Streptomyces sp MA37, Norcardia brasiliensis, and Actinoplanes sp N902-109 by genome mining. Chembiochem : a European Journal of Chemical Biology. 15: 364-8. PMID 24449539 DOI: 10.1002/cbic.201300732  1
2013 Giannoulis A, Ward R, Branigan E, Naismith JH, Bode BE. PELDOR in rotationally symmetric homo-oligomers. Molecular Physics. 111: 2845-2854. PMID 24954956 DOI: 10.1080/00268976.2013.798697  1
2013 Koehnke J, Bent AF, Zollman D, Smith K, Houssen WE, Zhu X, Mann G, Lebl T, Scharff R, Shirran S, Botting CH, Jaspars M, Schwarz-Linek U, Naismith JH. The cyanobactin heterocyclase enzyme: a processive adenylase that operates with a defined order of reaction. Angewandte Chemie (International Ed. in English). 52: 13991-6. PMID 24214017 DOI: 10.1002/anie.201306302  1
2013 Branigan E, Pliotas C, Hagelueken G, Naismith JH. Quantification of free cysteines in membrane and soluble proteins using a fluorescent dye and thermal unfolding. Nature Protocols. 8: 2090-7. PMID 24091556 DOI: 10.1038/nprot.2013.128  1
2013 Warelow TP, Oke M, Schoepp-Cothenet B, Dahl JU, Bruselat N, Sivalingam GN, Leimkühler S, Thalassinos K, Kappler U, Naismith JH, Santini JM. The respiratory arsenite oxidase: structure and the role of residues surrounding the rieske cluster. Plos One. 8: e72535. PMID 24023621 DOI: 10.1371/journal.pone.0072535  1
2013 Cukier CD, Hope AG, Elamin AA, Moynie L, Schnell R, Schach S, Kneuper H, Singh M, Naismith JH, Lindqvist Y, Gray DW, Schneider G. Discovery of an allosteric inhibitor binding site in 3-Oxo-acyl-ACP reductase from Pseudomonas aeruginosa. Acs Chemical Biology. 8: 2518-27. PMID 24015914 DOI: 10.1021/cb4005063  1
2013 Wadsworth JM, Clarke DJ, McMahon SA, Lowther JP, Beattie AE, Langridge-Smith PR, Broughton HB, Dunn TM, Naismith JH, Campopiano DJ. The chemical basis of serine palmitoyltransferase inhibition by myriocin. Journal of the American Chemical Society. 135: 14276-85. PMID 23957439 DOI: 10.1021/ja4059876  1
2013 Reeks J, Graham S, Anderson L, Liu H, White MF, Naismith JH. Structure of the archaeal Cascade subunit Csa5: relating the small subunits of CRISPR effector complexes. Rna Biology. 10: 762-9. PMID 23846216 DOI: 10.4161/rna.23854  1
2013 Reeks J, Naismith JH, White MF. CRISPR interference: a structural perspective. The Biochemical Journal. 453: 155-66. PMID 23805973 DOI: 10.1042/BJ20130316  1
2013 Bent AF, Koehnke J, Houssen WE, Smith MC, Jaspars M, Naismith JH. Structure of PatF from Prochloron didemni. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 618-23. PMID 23722837 DOI: 10.1107/S1744309113012931  1
2013 Bushell SR, Mainprize IL, Wear MA, Lou H, Whitfield C, Naismith JH. Wzi is an outer membrane lectin that underpins group 1 capsule assembly in Escherichia coli. Structure (London, England : 1993). 21: 844-53. PMID 23623732 DOI: 10.1016/j.str.2013.03.010  1
2013 Reeks J, Sokolowski RD, Graham S, Liu H, Naismith JH, White MF. Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing. The Biochemical Journal. 452: 223-30. PMID 23527601 DOI: 10.1042/BJ20130269  1
2013 Koehnke J, Morawitz F, Bent AF, Houssen WE, Shirran SL, Fuszard MA, Smellie IA, Botting CH, Smith MC, Jaspars M, Naismith JH. An enzymatic route to selenazolines. Chembiochem : a European Journal of Chemical Biology. 14: 564-7. PMID 23483642 DOI: 10.1002/cbic.201300037  1
2013 Moynie L, Schnell R, McMahon SA, Sandalova T, Boulkerou WA, Schmidberger JW, Alphey M, Cukier C, Duthie F, Kopec J, Liu H, Jacewicz A, Hunter WN, Naismith JH, Schneider G. The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 25-34. PMID 23295481 DOI: 10.1107/S1744309112044739  1
2013 Moynié L, Leckie SM, McMahon SA, Duthie FG, Koehnke A, Taylor JW, Alphey MS, Brenk R, Smith AD, Naismith JH. Structural insights into the mechanism and inhibition of the β-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa. Journal of Molecular Biology. 425: 365-77. PMID 23174186 DOI: 10.1016/j.jmb.2012.11.017  1
2013 Alphey MS, Pirrie L, Torrie LS, Boulkeroua WA, Gardiner M, Sarkar A, Maringer M, Oehlmann W, Brenk R, Scherman MS, McNeil M, Rejzek M, Field RA, Singh M, Gray D, ... ... Naismith JH, et al. Allosteric competitive inhibitors of the glucose-1-phosphate thymidylyltransferase (RmlA) from Pseudomonas aeruginosa. Acs Chemical Biology. 8: 387-96. PMID 23138692 DOI: 10.1021/cb300426u  1
2012 Houssen WE, Koehnke J, Zollman D, Vendome J, Raab A, Smith MC, Naismith JH, Jaspars M. The discovery of new cyanobactins from Cyanothece PCC 7425 defines a new signature for processing of patellamides. Chembiochem : a European Journal of Chemical Biology. 13: 2683-9. PMID 23169461 DOI: 10.1002/cbic.201200661  1
2012 Pliotas C, Ward R, Branigan E, Rasmussen A, Hagelueken G, Huang H, Black SS, Booth IR, Schiemann O, Naismith JH. Conformational state of the MscS mechanosensitive channel in solution revealed by pulsed electron-electron double resonance (PELDOR) spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 109: E2675-82. PMID 23012406 DOI: 10.1073/pnas.1202286109  1
2012 Hagelueken G, Huang H, Harlos K, Clarke BR, Whitfield C, Naismith JH. Crystallization, dehydration and experimental phasing of WbdD, a bifunctional kinase and methyltransferase from Escherichia coli O9a. Acta Crystallographica. Section D, Biological Crystallography. 68: 1371-9. PMID 22993091 DOI: 10.1107/S0907444912029599  1
2012 Hagelueken G, Huang H, Clarke BR, Lebl T, Whitfield C, Naismith JH. Structure of WbdD: a bifunctional kinase and methyltransferase that regulates the chain length of the O antigen in Escherichia coli O9a. Molecular Microbiology. 86: 730-42. PMID 22970759 DOI: 10.1111/mmi.12014  1
2012 Plechanovová A, Jaffray EG, Tatham MH, Naismith JH, Hay RT. Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis. Nature. 489: 115-20. PMID 22842904 DOI: 10.1038/nature11376  1
2012 Koehnke J, Bent A, Houssen WE, Zollman D, Morawitz F, Shirran S, Vendome J, Nneoyiegbe AF, Trembleau L, Botting CH, Smith MC, Jaspars M, Naismith JH. The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain. Nature Structural & Molecular Biology. 19: 767-72. PMID 22796963 DOI: 10.1038/nsmb.2340  1
2012 Lowther J, Naismith JH, Dunn TM, Campopiano DJ. Structural, mechanistic and regulatory studies of serine palmitoyltransferase. Biochemical Society Transactions. 40: 547-54. PMID 22616865 DOI: 10.1042/BST20110769  1
2012 Naismith JH. Tryptophan oxygenation: mechanistic considerations. Biochemical Society Transactions. 40: 509-14. PMID 22616860 DOI: 10.1042/BST20120073  1
2012 Hagelueken G, Ward R, Naismith JH, Schiemann O. MtsslWizard: In Silico Spin-Labeling and Generation of Distance Distributions in PyMOL. Applied Magnetic Resonance. 42: 377-391. PMID 22448103 DOI: 10.1007/s00723-012-0314-0  1
2012 Naismith JH, Booth IR. Bacterial mechanosensitive channels--MscS: evolution's solution to creating sensitivity in function. Annual Review of Biophysics. 41: 157-77. PMID 22404681 DOI: 10.1146/annurev-biophys-101211-113227  1
2012 Zhang J, Rouillon C, Kerou M, Reeks J, Brugger K, Graham S, Reimann J, Cannone G, Liu H, Albers SV, Naismith JH, Spagnolo L, White MF. Structure and Mechanism of the CMR Complex for CRISPR-Mediated Antiviral Immunity Molecular Cell. 45: 303-313. PMID 22227115 DOI: 10.1016/j.molcel.2011.12.013  1
2012 Wang W, Rasmussen T, Harding AJ, Booth NA, Booth IR, Naismith JH. Salt bridges regulate both dimer formation and monomeric flexibility in HdeB and may have a role in periplasmic chaperone function. Journal of Molecular Biology. 415: 538-46. PMID 22138344 DOI: 10.1016/j.jmb.2011.11.026  1
2012 Paytubi S, McMahon SA, Graham S, Liu H, Botting CH, Makarova KS, Koonin EV, Naismith JH, White MF. Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales. Proceedings of the National Academy of Sciences of the United States of America. 109: E398-405. PMID 22106294 DOI: 10.1073/pnas.1113277108  1
2011 Lou H, Chen M, Black SS, Bushell SR, Ceccarelli M, Mach T, Beis K, Low AS, Bamford VA, Booth IR, Bayley H, Naismith JH. Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli. Plos One. 6: e25825. PMID 22053181 DOI: 10.1371/journal.pone.0025825  1
2011 Plechanovová A, Jaffray EG, McMahon SA, Johnson KA, Navrátilová I, Naismith JH, Hay RT. Mechanism of ubiquitylation by dimeric RING ligase RNF4. Nature Structural & Molecular Biology. 18: 1052-9. PMID 21857666 DOI: 10.1038/nsmb.2108  1
2011 Schmelz S, Botting CH, Song L, Kadi NF, Challis GL, Naismith JH. Structural basis for acyl acceptor specificity in the achromobactin biosynthetic enzyme AcsD. Journal of Molecular Biology. 412: 495-504. PMID 21835184 DOI: 10.1016/j.jmb.2011.07.059  1
2011 Wilfong EM, Kogiso Y, Muthukrishnan S, Kowatz T, Du Y, Bowie A, Naismith JH, Hadad CM, Toone EJ, Gustafson TL. A multidisciplinary approach to probing enthalpy-entropy compensation and the interfacial mobility model. Journal of the American Chemical Society. 133: 11515-23. PMID 21692482 DOI: 10.1021/ja1098287  1
2011 Compton EL, Karinou E, Naismith JH, Gabel F, Javelle A. Low resolution structure of a bacterial SLC26 transporter reveals dimeric stoichiometry and mobile intracellular domains. The Journal of Biological Chemistry. 286: 27058-67. PMID 21659513 DOI: 10.1074/jbc.M111.244533  1
2011 Lintner NG, Kerou M, Brumfield SK, Graham S, Liu H, Naismith JH, Sdano M, Peng N, She Q, Copié V, Young MJ, White MF, Lawrence CM. Structural and functional characterization of an archaeal clustered regularly interspaced short palindromic repeat (CRISPR)-associated complex for antiviral defense (CASCADE). The Journal of Biological Chemistry. 286: 21643-56. PMID 21507944 DOI: 10.1074/jbc.M111.238485  1
2011 Lang A, Polnick S, Nicke T, William P, Patallo EP, Naismith JH, van Pée KH. Changing the regioselectivity of the tryptophan 7-halogenase PrnA by site-directed mutagenesis. Angewandte Chemie (International Ed. in English). 50: 2951-3. PMID 21404376 DOI: 10.1002/anie.201007896  1
2011 Harrison JA, Kartha KP, Fournier EJ, Lowary TL, Malet C, Nilsson UJ, Hindsgaul O, Schenkman S, Naismith JH, Field RA. Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries. Organic & Biomolecular Chemistry. 9: 1653-60. PMID 21253654 DOI: 10.1039/c0ob00826e  1
2011 Oke M, Kerou M, Liu H, Peng X, Garrett RA, Prangishvili D, Naismith JH, White MF. A dimeric Rep protein initiates replication of a linear archaeal virus genome: implications for the Rep mechanism and viral replication. Journal of Virology. 85: 925-31. PMID 21068244 DOI: 10.1128/JVI.01467-10  1
2010 Bushell SR, Lou H, Wallat GD, Beis K, Whitfield C, Naismith JH. Crystallization and preliminary diffraction analysis of Wzi, a member of the capsule export and assembly pathway in Escherichia coli. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1621-5. PMID 21139210 DOI: 10.1107/S1744309110040546  1
2010 Hagan RM, Björnsson R, McMahon SA, Schomburg B, Braithwaite V, Bühl M, Naismith JH, Schwarz-Linek U. NMR spectroscopic and theoretical analysis of a spontaneously formed Lys-Asp isopeptide bond. Angewandte Chemie (International Ed. in English). 49: 8421-5. PMID 20878961 DOI: 10.1002/anie.201004340  1
2010 Raman MC, Johnson KA, Clarke DJ, Naismith JH, Campopiano DJ. The serine palmitoyltransferase from Sphingomonas wittichii RW1: An interesting link to an unusual acyl carrier protein. Biopolymers. 93: 811-22. PMID 20578000 DOI: 10.1002/bip.21482  1
2010 Kowatz T, Morrison JP, Tanner ME, Naismith JH. The crystal structure of the Y140F mutant of ADP-L-glycero-D-manno-heptose 6-epimerase bound to ADP-β-D-mannose suggests a one base mechanism Protein Science. 19: 1337-1343. PMID 20506248 DOI: 10.1002/pro.410  1
2010 Lowther J, Yard BA, Johnson KA, Carter LG, Bhat VT, Raman MC, Clarke DJ, Ramakers B, McMahon SA, Naismith JH, Campopiano DJ. Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation. Molecular Biosystems. 6: 1682-93. PMID 20445930 DOI: 10.1039/c003743e  1
2010 Zhu X, van Pée KH, Naismith JH. The ternary complex of PrnB (the second enzyme in the pyrrolnitrin biosynthesis pathway), tryptophan, and cyanide yields new mechanistic insights into the indolamine dioxygenase superfamily. The Journal of Biological Chemistry. 285: 21126-33. PMID 20421301 DOI: 10.1074/jbc.M110.120485  1
2010 Oke M, Carter LG, Johnson KA, Liu H, McMahon SA, Yan X, Kerou M, Weikart ND, Kadi N, Sheikh MA, Schmelz S, Dorward M, Zawadzki M, Cozens C, Falconer H, ... ... Naismith JH, et al. The Scottish Structural Proteomics Facility: targets, methods and outputs. Journal of Structural and Functional Genomics. 11: 167-80. PMID 20419351 DOI: 10.1007/s10969-010-9090-y  1
2010 Schmidberger JW, James AB, Edwards R, Naismith JH, O'Hagan D. Halomethane biosynthesis: structure of a SAM-dependent halide methyltransferase from Arabidopsis thaliana. Angewandte Chemie (International Ed. in English). 49: 3646-8. PMID 20376845 DOI: 10.1002/anie.201000119  1
2010 Steiner K, Hagelueken G, Messner P, Schäffer C, Naismith JH. Structural basis of substrate binding in WsaF, a rhamnosyltransferase from Geobacillus stearothermophilus. Journal of Molecular Biology. 397: 436-47. PMID 20097205 DOI: 10.1016/j.jmb.2010.01.035  1
2009 Schmelz S, Naismith JH. Adenylate-forming enzymes. Current Opinion in Structural Biology. 19: 666-71. PMID 19836944 DOI: 10.1016/j.sbi.2009.09.004  1
2009 Deng H, McMahon SA, Eustáquio AS, Moore BS, Naismith JH, O'Hagan D. Mechanistic insights into water activation in SAM hydroxide adenosyltransferase (duf-62). Chembiochem : a European Journal of Chemical Biology. 10: 2455-9. PMID 19739191 DOI: 10.1002/cbic.200900369  1
2009 Huang H, Hagelueken G, Whitfield C, Naismith JH. Crystallization and preliminary crystallographic analysis of the bacterial capsule assembly-regulating tyrosine phosphatases Wzb of Escherichia coli and Cps4B of Streptococcus pneumoniae. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 770-2. PMID 19652335 DOI: 10.1107/S1744309109023914  1
2009 Hagelueken G, Huang H, Mainprize IL, Whitfield C, Naismith JH. Crystal structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, representatives of two families of tyrosine phosphatases that regulate capsule assembly. Journal of Molecular Biology. 392: 678-88. PMID 19616007 DOI: 10.1016/j.jmb.2009.07.026  1
2009 McMahon SA, Roberts GA, Johnson KA, Cooper LP, Liu H, White JH, Carter LG, Sanghvi B, Oke M, Walkinshaw MD, Blakely GW, Naismith JH, Dryden DT. Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance. Nucleic Acids Research. 37: 4887-97. PMID 19506028 DOI: 10.1093/nar/gkp478  1
2009 Zhu X, De Laurentis W, Leang K, Herrmann J, Ihlefeld K, van Pée KH, Naismith JH. Structural insights into regioselectivity in the enzymatic chlorination of tryptophan. Journal of Molecular Biology. 391: 74-85. PMID 19501593 DOI: 10.1016/j.jmb.2009.06.008  1
2009 McRobbie AM, Carter LG, Kerou M, Liu H, McMahon SA, Johnson KA, Oke M, Naismith JH, White MF. Structural and functional characterisation of a conserved archaeal RadA paralog with antirecombinase activity. Journal of Molecular Biology. 389: 661-73. PMID 19414020 DOI: 10.1016/j.jmb.2009.04.060  1
2009 Raman MC, Johnson KA, Yard BA, Lowther J, Carter LG, Naismith JH, Campopiano DJ. The external aldimine form of serine palmitoyltransferase: structural, kinetic, and spectroscopic analysis of the wild-type enzyme and HSAN1 mutant mimics. The Journal of Biological Chemistry. 284: 17328-39. PMID 19376777 DOI: 10.1074/jbc.M109.008680  1
2009 Hagelueken G, Ingledew WJ, Huang H, Petrovic-Stojanovska B, Whitfield C, ElMkami H, Schiemann O, Naismith JH. PELDOR spectroscopy distance fingerprinting of the octameric outer-membrane protein Wza from Escherichia coli. Angewandte Chemie (International Ed. in English). 48: 2904-6. PMID 19294709 DOI: 10.1002/anie.200805758  1
2009 Rejzek M, Sri Kannathasan V, Wing C, Preston A, Westman EL, Lam JS, Naismith JH, Maskell DJ, Field RA. Chemical synthesis of UDP-Glc-2,3-diNAcA, a key intermediate in cell surface polysaccharide biosynthesis in the human respiratory pathogens B. pertussis and P. aeruginosa. Organic & Biomolecular Chemistry. 7: 1203-10. PMID 19262941 DOI: 10.1039/b819607a  1
2009 Cuthbertson L, Mainprize IL, Naismith JH, Whitfield C. Pivotal roles of the outer membrane polysaccharide export and polysaccharide copolymerase protein families in export of extracellular polysaccharides in gram-negative bacteria. Microbiology and Molecular Biology Reviews : Mmbr. 73: 155-77. PMID 19258536 DOI: 10.1128/MMBR.00024-08  1
2009 Ford RC, Brunkan-LaMontagne AL, Collins RF, Clarke BR, Harris R, Naismith JH, Whitfield C. Structure-function relationships of the outer membrane translocon Wza investigated by cryo-electron microscopy and mutagenesis. Journal of Structural Biology. 166: 172-82. PMID 19236919 DOI: 10.1016/j.jsb.2009.02.005  1
2009 Errey JC, Mann MC, Fairhurst SA, Hill L, McNeil MR, Naismith JH, Percy JM, Whitfield C, Field RA. Sugar nucleotide recognition by Klebsiella pneumoniae UDP-D-galactopyranose mutase: fluorinated substrates, kinetics and equilibria. Organic & Biomolecular Chemistry. 7: 1009-16. PMID 19225684 DOI: 10.1039/b815549f  1
2009 Schmelz S, Kadi N, McMahon SA, Song L, Oves-Costales D, Oke M, Liu H, Johnson KA, Carter LG, Botting CH, White MF, Challis GL, Naismith JH. AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis. Nature Chemical Biology. 5: 174-82. PMID 19182782 DOI: 10.1038/nchembio.145  1
2009 Liu H, Naismith JH. A simple and efficient expression and purification system using two newly constructed vectors. Protein Expression and Purification. 63: 102-11. PMID 18845260 DOI: 10.1016/j.pep.2008.09.008  1
2009 Lou H, Beis K, Naismith JH. Chapter 11 Bacterial Membrane Proteins. The New Soluble Proteins? Current Topics in Membranes. 63: 269-297. DOI: 10.1016/S1063-5823(09)63011-8  1
2008 Liu H, Naismith JH. An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol. Bmc Biotechnology. 8: 91. PMID 19055817 DOI: 10.1186/1472-6750-8-91  1
2008 Steiner K, Wojciechowska A, Schäffer C, Naismith JH. Purification, crystallization and preliminary crystallographic analysis of WsaF, an essential rhamnosyltransferase from Geobacillus stearothermophilus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 1163-5. PMID 19052376 DOI: 10.1107/S1744309108036762  1
2008 McMahon SA, Oke M, Liu H, Johnson KA, Carter L, Kadi N, White MF, Challis GL, Naismith JH. Purification, crystallization and data collection of Pectobacterium chrysanthemi AcsD, a type A siderophore synthetase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 1052-5. PMID 18997340 DOI: 10.1107/S1744309108032132  1
2008 Flecks S, Patallo EP, Zhu X, Ernyei AJ, Seifert G, Schneider A, Dong C, Naismith JH, van Pée KH. New insights into the mechanism of enzymatic chlorination of tryptophan. Angewandte Chemie (International Ed. in English). 47: 9533-6. PMID 18979475 DOI: 10.1002/anie.200802466  1
2008 Davies GJ, Naismith JH. Chemistry's prodigal child: enzyme mechanism. Current Opinion in Chemical Biology. 12: 529-31. PMID 18793749 DOI: 10.1016/j.cbpa.2008.08.018  1
2008 Oke M, Ching RT, Carter LG, Johnson KA, Liu H, McMahon SA, White MF, Bloch C, Botting CH, Walsh MA, Latiff AA, Kennedy MW, Cooper A, Naismith JH. Unusual chromophore and cross-links in ranasmurfin: a blue protein from the foam nests of a tropical frog. Angewandte Chemie (International Ed. in English). 47: 7853-6. PMID 18781570 DOI: 10.1002/anie.200802901  1
2008 Wang W, Black SS, Edwards MD, Miller S, Morrison EL, Bartlett W, Dong C, Naismith JH, Booth IR. The structure of an open form of an E. coli mechanosensitive channel at 3.45 A resolution. Science (New York, N.Y.). 321: 1179-83. PMID 18755969 DOI: 10.1126/science.1159262  1
2008 Wang W, Dong C, McNeil M, Kaur D, Mahapatra S, Crick DC, Naismith JH. The structural basis of chain length control in Rv1086. Journal of Molecular Biology. 381: 129-40. PMID 18597781 DOI: 10.1016/j.jmb.2008.05.060  1
2008 Liu H, Rudolf J, Johnson KA, McMahon SA, Oke M, Carter L, McRobbie AM, Brown SE, Naismith JH, White MF. Structure of the DNA repair helicase XPD. Cell. 133: 801-12. PMID 18510925 DOI: 10.1016/j.cell.2008.04.029  1
2008 Whitfield C, Naismith JH. Periplasmic export machines for outer membrane assembly. Current Opinion in Structural Biology. 18: 466-74. PMID 18495473 DOI: 10.1016/j.sbi.2008.04.001  1
2008 Overton IM, van Niekerk CA, Carter LG, Dawson A, Martin DM, Cameron S, McMahon SA, White MF, Hunter WN, Naismith JH, Barton GJ. TarO: a target optimisation system for structural biology. Nucleic Acids Research. 36: W190-6. PMID 18385152 DOI: 10.1093/nar/gkn141  1
2008 Fairhead M, Johnson KA, Kowatz T, McMahon SA, Carter LG, Oke M, Liu H, Naismith JH, van der Walle CF. Crystal structure and silica condensing activities of silicatein alpha-cathepsin L chimeras. Chemical Communications (Cambridge, England). 1765-7. PMID 18379686 DOI: 10.1039/b718264c  1
2008 Richards JD, Johnson KA, Liu H, McRobbie AM, McMahon S, Oke M, Carter L, Naismith JH, White MF. Structure of the DNA repair helicase hel308 reveals DNA binding and autoinhibitory domains. The Journal of Biological Chemistry. 283: 5118-26. PMID 18056710 DOI: 10.1074/jbc.M707548200  1
2008 Walters MJ, Srikannathasan V, McEwan AR, Naismith JH, Fierke CA, Toone EJ. Characterization and crystal structure of Escherichia coli KDPGal aldolase. Bioorganic & Medicinal Chemistry. 16: 710-20. PMID 17981470 DOI: 10.1016/j.bmc.2007.10.043  1
2008 Deng H, Huang FL, Naismith JH, O'Hagan D, Spencer JB, Zhu X. Biological Fluorination in Streptomyces cattleya: The Fluorinase Fluorine and Health. 761-777. DOI: 10.1016/B978-0-444-53086-8.00018-7  1
2007 Zhu X, Robinson DA, McEwan AR, O'Hagan D, Naismith JH. Mechanism of enzymatic fluorination in Streptomyces cattleya. Journal of the American Chemical Society. 129: 14597-604. PMID 17985882 DOI: 10.1021/ja0731569  1
2007 De Laurentis W, Khim L, Anderson JL, Adam A, Johnson KA, Phillips RS, Chapman SK, van Pee KH, Naismith JH. The second enzyme in pyrrolnitrin biosynthetic pathway is related to the heme-dependent dioxygenase superfamily. Biochemistry. 46: 12393-404. PMID 17924666 DOI: 10.1021/bi7012189  1
2007 Liu H, Woznica K, Catton G, Crawford A, Botting N, Naismith JH. Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens. Journal of Molecular Biology. 373: 755-63. PMID 17868694 DOI: 10.1016/j.jmb.2007.08.043  1
2007 Seetharamappa J, Oke M, Liu H, McMahon SA, Johnson KA, Carter L, Dorward M, Zawadzki M, Overton IM, van Niekirk CA, Graham S, Botting CH, Taylor GL, White MF, Barton GJ, ... ... Naismith JH, et al. Expression, purification, crystallization, data collection and preliminary biochemical characterization of methicillin-resistant Staphylococcus aureus Sar2028, an aspartate/tyrosine/phenylalanine pyridoxal-5'-phosphate-dependent aminotransferase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 452-6. PMID 17565195 DOI: 10.1107/S1744309107019562  1
2007 Yard BA, Carter LG, Johnson KA, Overton IM, Dorward M, Liu H, McMahon SA, Oke M, Puech D, Barton GJ, Naismith JH, Campopiano DJ. The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis. Journal of Molecular Biology. 370: 870-86. PMID 17559874 DOI: 10.1016/j.jmb.2007.04.086  1
2007 Seetharamappa J, Oke M, Liu H, McMahon SA, Johnson KA, Carter L, Dorward M, Zawadzki M, Overton IM, van Niekirk CA, Graham S, Botting CH, Taylor GL, White MF, Barton GJ, ... ... Naismith JH, et al. Purification, crystallization and data collection of methicillin-resistant Staphylococcus aureus Sar2676, a pantothenate synthetase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 488-91. PMID 17554169 DOI: 10.1107/S1744309107020362  1
2007 Collins RF, Beis K, Dong C, Botting CH, McDonnell C, Ford RC, Clarke BR, Whitfield C, Naismith JH. The 3D structure of a periplasm-spanning platform required for assembly of group 1 capsular polysaccharides in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 104: 2390-5. PMID 17283336 DOI: 10.1073/pnas.0607763104  1
2007 Dong C, Major LL, Srikannathasan V, Errey JC, Giraud MF, Lam JS, Graninger M, Messner P, McNeil MR, Field RA, Whitfield C, Naismith JH. RmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation. Journal of Molecular Biology. 365: 146-59. PMID 17046787 DOI: 10.1016/j.jmb.2006.09.063  1
2007 De Laurentis W, Khim L, Ross Anderson JL, Adam A, Johnson KA, Phillips RS, Chapman SK, Van Pee KH, Naismith JH. The second enzyme in pyrrolnitrin biosynthetic pathway is related to the heme-dependent dioxygenase superfamily (Biochemistry (2007) 46, 43, (12393-12404)) Biochemistry. 46: 14733. DOI: 10.1021/bi702167m  1
2006 Shen L, Tatham MH, Dong C, Zagórska A, Naismith JH, Hay RT. SUMO protease SENP1 induces isomerization of the scissile peptide bond Nature Structural and Molecular Biology. 13: 1069-1077. PMID 17099698 DOI: 10.1038/nsmb1172  1
2006 Dong C, Beis K, Nesper J, Brunkan-Lamontagne AL, Clarke BR, Whitfield C, Naismith JH. Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein. Nature. 444: 226-9. PMID 17086202 DOI: 10.1038/nature05267  1
2006 De Laurentis W, Leang K, Hahn K, Podemski B, Adam A, Kroschwald S, Carter LG, van Pee KH, Naismith JH. Preliminary crystallographic characterization of PrnB, the second enzyme in the pyrrolnitrin biosynthetic pathway. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 1134-7. PMID 17077497 DOI: 10.1107/S1744309106041649  1
2006 McMahon SA, Walsh MA, Ching RT, Carter LG, Dorward M, Johnson KA, Liu H, Oke M, Bloch C, Kennedy MW, Latiff AA, Cooper A, Taylor GL, White MF, Naismith JH. Crystallization of Ranasmurfin, a blue-coloured protein from Polypedates leucomystax. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 1124-6. PMID 17077494 DOI: 10.1107/S1744309106040036  1
2006 Williams GJ, Johnson K, Rudolf J, McMahon SA, Carter L, Oke M, Liu H, Taylor GL, White MF, Naismith JH. Structure of the heterotrimeric PCNA from Sulfolobus solfataricus Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 62: 944-948. PMID 17012780 DOI: 10.1107/S1744309106034075  1
2006 Naismith JH. Inferring the chemical mechanism from structures of enzymes Chemical Society Reviews. 35: 763-770. PMID 16936924 DOI: 10.1039/b602313d  1
2006 Cobb SL, Deng H, McEwan AR, Naismith JH, O'Hagan D, Robinson DA. Substrate specificity in enzymatic fluorination. The fluorinase from Streptomyces cattleya accepts 2'-deoxyadenosine substrates. Organic & Biomolecular Chemistry. 4: 1458-60. PMID 16604208 DOI: 10.1039/b600574h  1
2006 Shen LN, Dong C, Liu H, Naismith JH, Hay RT. The structure of SENP1-SUMO-2 complex suggests a structural basis for discrimination between SUMO paralogues during processing Biochemical Journal. 397: 279-288. PMID 16553580 DOI: 10.1042/BJ20052030  1
2006 McEwan AR, Liu H, Oke M, Carter L, Powers H, Dorward M, McMahon SA, White MF, Naismith JH. Overexpression, purification, crystallization and data collection of Sulfolobus solfataricus Sso6206, a novel highly conserved protein Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 62: 228-230. PMID 16511308 DOI: 10.1107/S1744309106003654  1
2006 Beis K, Whitfield C, Booth I, Naismith JH. Two-step purification of outer membrane proteins. International Journal of Biological Macromolecules. 39: 10-4. PMID 16423387 DOI: 10.1016/j.ijbiomac.2005.12.008  1
2006 Fullerton SW, Griffiths JS, Merkel AB, Cheriyan M, Wymer NJ, Hutchins MJ, Fierke CA, Toone EJ, Naismith JH. Mechanism of the Class I KDPG aldolase. Bioorganic & Medicinal Chemistry. 14: 3002-10. PMID 16403639 DOI: 10.1016/j.bmc.2005.12.022  1
2006 Deng H, Cobb SL, McEwan AR, McGlinchey RP, Naismith JH, O'Hagan D, Robinson DA, Spencer JB. The fluorinase from Streptomyces cattleya is also a chlorinase. Angewandte Chemie (International Ed. in English). 45: 759-62. PMID 16370017 DOI: 10.1002/anie.200503582  1
2006 Collins RF, Beis K, Clarke BR, Ford RC, Hulley M, Naismith JH, Whitfield C. Periplasmic protein-protein contacts in the inner membrane protein Wzc form a tetrameric complex required for the assembly of Escherichia coli group 1 capsules. The Journal of Biological Chemistry. 281: 2144-50. PMID 16172129 DOI: 10.1074/jbc.M508078200  1
2006 Seibold C, Schnerr H, Rumpf J, Kunzendorf A, Hatscher C, Wage T, Ernyei AJ, Dong C, Naismith JH, van Pée KH. A flavin-dependent tryptophan 6-halogenase and its use in modification of pyrrolnitrin biosynthesis Biocatalysis and Biotransformation. 24: 401-408. DOI: 10.1080/10242420601033738  1
2005 Major LL, Wolucka BA, Naismith JH. Structure and function of GDP-mannose-3′,5′-epimerase: An enzyme which performs three chemical reactions at the same active site Journal of the American Chemical Society. 127: 18309-18320. PMID 16366586 DOI: 10.1021/ja056490i  1
2005 Dong C, Flecks S, Unversucht S, Haupt C, Van Pée KH, Naismith JH. Structural biology: Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination Science. 309: 2216-2219. PMID 16195462 DOI: 10.1126/science.1116510  1
2005 Beis K, Srikannathasan V, Liu H, Fullerton SW, Bamford VA, Sanders DA, Whitfield C, McNeil MR, Naismith JH. Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state. Journal of Molecular Biology. 348: 971-82. PMID 15843027 DOI: 10.1016/j.jmb.2005.02.057  1
2005 Williams GJ, Breazeale SD, Raetz CR, Naismith JH. Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis. The Journal of Biological Chemistry. 280: 23000-8. PMID 15809294 DOI: 10.1074/jbc.M501534200  1
2005 Shen LN, Liu H, Dong C, Xirodimas D, Naismith JH, Hay RT. Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1 Embo Journal. 24: 1341-1351. PMID 15775960 DOI: 10.1038/sj.emboj.7600628  1
2004 Challis GL, Naismith JH. Structural aspects of non-ribosomal peptide biosynthesis Current Opinion in Structural Biology. 14: 748-756. PMID 15582399 DOI: 10.1016/j.sbi.2004.10.005  1
2004 Naismith JH. Chemical insights from structural studies of enzymes Biochemical Society Transactions. 32: 647-654. PMID 15493979 DOI: 10.1042/BST0320647  1
2004 Dong C, Kotzsch A, Dorward M, Van Pée KH, Naismith JH. Crystallization and X-ray diffraction of a halogenating enzyme, tryptophan 7-halogenase, from Pseudomonas fluorescens Acta Crystallographica Section D: Biological Crystallography. 60: 1438-1440. PMID 15272170 DOI: 10.1107/S0907444904012521  1
2004 Merkel AB, Major LL, Errey JC, Burkart MD, Field RA, Walsh CT, Naismith JH. The position of a key tyrosine in dTDP-4-Keto-6-deoxy-D-glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme. The Journal of Biological Chemistry. 279: 32684-91. PMID 15159413 DOI: 10.1074/jbc.M404091200  1
2004 Beis K, Collins RF, Ford RC, Kamis AB, Whitfield C, Naismith JH. Three-dimensional structure of Wza, the protein required for translocation of group 1 capsular polysaccharide across the outer membrane of Escherichia coli. The Journal of Biological Chemistry. 279: 28227-32. PMID 15090537 DOI: 10.1074/jbc.M402913200  1
2004 Beis K, Nesper J, Whitfield C, Naismith JH. Crystallization and preliminary X-ray diffraction analysis of Wza outer-membrane lipoprotein from Escherichia coli serotype O9a:K30. Acta Crystallographica. Section D, Biological Crystallography. 60: 558-60. PMID 14993692 DOI: 10.1107/S0907444903029494  1
2004 Dong C, Huang F, Deng H, Schaffrath C, Spencer JB, O'Hagan D, Naismith JH. Crystal structure and mechanism of a bacterial fluorinating enzyme. Nature. 427: 561-5. PMID 14765200 DOI: 10.1038/nature02280  1
2003 Dong C, Deng H, Dorward M, Schaffrath C, O'Hagan D, Naismith JH. Crystallization and X-ray diffraction of 5'-fluoro-5'-deoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya. Acta Crystallographica. Section D, Biological Crystallography. 59: 2292-3. PMID 14646098 DOI: 10.1107/S0907444903019826  1
2003 Nesper J, Hill CM, Paiment A, Harauz G, Beis K, Naismith JH, Whitfield C. Translocation of group 1 capsular polysaccharide in Escherichia coli serotype K30. Structural and functional analysis of the outer membrane lipoprotein Wza. The Journal of Biological Chemistry. 278: 49763-72. PMID 14522970 DOI: 10.1074/jbc.M308775200  1
2003 Beis K, Allard ST, Hegeman AD, Murshudov G, Philp D, Naismith JH. The structure of NADH in the enzyme dTDP-d-glucose dehydratase (RmlB). Journal of the American Chemical Society. 125: 11872-8. PMID 14505409 DOI: 10.1021/ja035796r  1
2003 Rahn A, Beis K, Naismith JH, Whitfield C. A novel outer membrane protein, Wzi, is involved in surface assembly of the Escherichia coli K30 group 1 capsule. Journal of Bacteriology. 185: 5882-90. PMID 13129961 DOI: 10.1128/JB.185.19.5882-5890.2003  1
2003 Babaoglu K, Page MA, Jones VC, McNeil MR, Dong C, Naismith JH, Lee RE. Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis Bioorganic and Medicinal Chemistry Letters. 13: 3227-3230. PMID 12951098 DOI: 10.1016/S0960-894X(03)00673-5  1
2003 Ramsay RR, Naismith JH. A snapshot of carnitine acetyltransferase Trends in Biochemical Sciences. 28: 343-346. PMID 12877997 DOI: 10.1016/S0968-0004(03)00137-3  1
2003 Field RA, Naismith JH. Structural and mechanistic basis of bacterial sugar nucleotide-modifying enzymes Biochemistry. 42: 7637-7647. PMID 12820872 DOI: 10.1021/bi0345079  1
2003 Dong C, Major LL, Allen A, Blankenfeldt W, Maskell D, Naismith JH. High-resolution structures of RmlC from Streptococcus suis in complex with substrate analogs locate the active site of this class of enzyme Structure. 11: 715-723. PMID 12791259 DOI: 10.1016/S0969-2126(03)00098-4  1
2003 Kerr ID, Wadsworth RI, Cubeddu L, Blankenfeldt W, Naismith JH, White MF. Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein. The Embo Journal. 22: 2561-70. PMID 12773373 DOI: 10.1093/emboj/cdg272  1
2003 Dong C, Beis K, Giraud MF, Blankenfeldt W, Allard S, Major LL, Kerr ID, Whitfield C, Naismith JH. A structural perspective on the enzymes that convert dTDP-D-glucose into dTDP-L-rhamnose Biochemical Society Transactions. 31: 532-536. PMID 12773151 DOI: 10.1042/BST0310532  1
2003 Liu H, Naismith JH, Hay RT. Adenovirus DNA replication Current Topics in Microbiology and Immunology. 272: 131-164. PMID 12747549  1
2003 Fullerton SW, Daff S, Sanders DA, Ingledew WJ, Whitfield C, Chapman SK, Naismith JH. Potentiometric analysis of UDP-galactopyranose mutase: stabilization of the flavosemiquinone by substrate. Biochemistry. 42: 2104-9. PMID 12590598 DOI: 10.1021/bi027077f  1
2002 Kannathasan VS, Dong CJ, Wing C, Preston A, Maskell DJ, Naismith JH, Field RA. Biochemical and Structural Analysis of the Role of the Wlb Gene Locus in Bordetella Pertussis Lipopolysaccharide Biosynthesis. Thescientificworldjournal. 2: 55-56. PMID 29973802 DOI: 10.1100/tsw.2002.28  1
2002 Merkel AB, Temple GK, Burkart MD, Losey HC, Beis K, Walsh CT, Naismith JH. Purification, crystallization and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis, the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway. Acta Crystallographica. Section D, Biological Crystallography. 58: 1226-8. PMID 12077451 DOI: 10.1107/S0907444902007382  1
2002 Blankenfeldt W, Kerr ID, Giraud MF, McMiken HJ, Leonard G, Whitfield C, Messner P, Graninger M, Naismith JH. Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode. Structure (London, England : 1993). 10: 773-86. PMID 12057193 DOI: 10.1016/S0969-2126(02)00770-0  1
2002 Allard ST, Beis K, Giraud MF, Hegeman AD, Gross JW, Wilmouth RC, Whitfield C, Graninger M, Messner P, Allen AG, Maskell DJ, Naismith JH. Toward a structural understanding of the dehydratase mechanism. Structure (London, England : 1993). 10: 81-92. PMID 11796113 DOI: 10.1016/S0969-2126(01)00694-3  1
2002 Asuncion M, Blankenfeldt W, Barlow JN, Gani D, Naismith JH. The structure of 3-methylaspartase from Clostridium tetanomorphum functions via the common enolase chemical step. The Journal of Biological Chemistry. 277: 8306-11. PMID 11748244 DOI: 10.1074/jbc.M111180200  1
2001 Allard STM, Giraud MF, Naismith JH. Epimerases: Structure, function and mechanism Cellular and Molecular Life Sciences. 58: 1650-1665. PMID 11706991  1
2001 Sanders DAR, Staines AG, McMahon SA, McNeil MR, Whitfield C, Naismith JH. UDP-galactopyranose mutase has a novel structure and mechanism Nature Structural Biology. 8: 858-863. PMID 11573090 DOI: 10.1038/nsb1001-858  1
2001 Sanders DA, McMahon SA, Leonard GL, Naismith JH. Molecular placement of experimental electron density: a case study on UDP-galactopyranose mutase. Acta Crystallographica. Section D, Biological Crystallography. 57: 1415-20. PMID 11567154 DOI: 10.1107/S0907444901009829  1
2001 Sri Kannathasan V, Staines AG, Dong CJ, Field RA, Preston AG, Maskell DJ, Naismith JH. Overexpression, purification, crystallization and data collection on the Bordetella pertussis wlbD gene product, a putative UDP-GlcNAc 2'-epimerase. Acta Crystallographica. Section D, Biological Crystallography. 57: 1310-2. PMID 11526328 DOI: 10.1107/S0907444901010885  1
2001 Kerr ID, Wadsworth RI, Blankenfeldt W, Staines AG, White MF, Naismith JH. Overexpression, purification, crystallization and data collection of a single-stranded DNA-binding protein from Sulfolobus solfataricus. Acta Crystallographica. Section D, Biological Crystallography. 57: 1290-2. PMID 11526322 DOI: 10.1107/S0907444901011374  1
2001 Bryce RA, Hillier IH, Naismith JH. Carbohydrate-protein recognition: molecular dynamics simulations and free energy analysis of oligosaccharide binding to concanavalin A. Biophysical Journal. 81: 1373-88. PMID 11509352 DOI: 10.1016/S0006-3495(01)75793-1  1
2001 Sanders DA, Moothoo DN, Raftery J, Howard AJ, Helliwell JR, Naismith JH. The 1.2 A resolution structure of the Con A-dimannose complex. Journal of Molecular Biology. 310: 875-84. PMID 11453694 DOI: 10.1006/jmbi.2001.4806  1
2001 Tatham MH, Jaffray E, Vaughan OA, Desterro JMP, Botting CH, Naismith JH, Hay RT. Polymeric Chains of SUMO-2 and SUMO-3 are Conjugated to Protein Substrates by SAE1/SAE2 and Ubc9 Journal of Biological Chemistry. 276: 35368-35374. PMID 11451954 DOI: 10.1074/jbc.M104214200  1
2001 Wymer N, Buchanan LV, Henderson D, Mehta N, Botting CH, Pocivavsek L, Fierke CA, Toone EJ, Naismith JH. Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli. Structure (London, England : 1993). 9: 1-9. PMID 11342129 DOI: 10.1016/S0969-2126(00)00555-4  1
2001 Asuncion M, Barlow JN, Pollard J, Staines AG, McMahon SA, Blankenfeldt W, Gani D, Naismith JH. Overexpression, purification, crystallization and data collection of 3-methylaspartase from Clostridium tetanomorphum. Acta Crystallographica. Section D, Biological Crystallography. 57: 731-3. PMID 11320320 DOI: 10.1107/S0907444901003225  1
2001 Allard STM, Giraud MF, Whitfield C, Graninger M, Messner P, Naismith JH. The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium, the second enzyme in the dTDP-L-rhamnose pathway Journal of Molecular Biology. 307: 283-295. PMID 11243820 DOI: 10.1006/jmbi.2000.4470  1
2001 Harrison JA, Kartha KP, Turnbull WB, Scheuerl SL, Naismith JH, Schenkman S, Field RA. Hydrolase and sialyltransferase activities of trypanosoma cruzi trans-sialidase towards NeuAc-alpha-2,3-gal-Gal-beta-O-PNP. Bioorganic & Medicinal Chemistry Letters. 11: 141-4. PMID 11206445 DOI: 10.1016/S0960-894X(00)00611-9  1
2000 Blankenfeldt W, Asuncion M, Lam JS, Naismith JH. The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (RmlA) Embo Journal. 19: 6652-6663. PMID 11118200 DOI: 10.1093/emboj/19.24.6652  1
2000 Giraud MF, Naismith JH. The rhamnose pathway Current Opinion in Structural Biology. 10: 687-696. PMID 11114506 DOI: 10.1016/S0959-440X(00)00145-7  1
2000 Liu H, Naismith JH, Hay RT. Identification of conserved residues contributing to the activities of adenovirus DNA polymerase Journal of Virology. 74: 11681-11689. PMID 11090167 DOI: 10.1128/JVI.74.24.11681-11689.2000  1
2000 Blankenfeldt W, Giraud MF, Leonard G, Rahim R, Creuzenet C, Lam JS, Naismith JH. The purification, crystallization and preliminary structural characterization of glucose-1-phosphate thymidylyltransferase (RmlA), the first enzyme of the dTDP-L-rhamnose synthesis pathway from Pseudomonas aeruginosa. Acta Crystallographica. Section D, Biological Crystallography. 56: 1501-4. PMID 11053865 DOI: 10.1107/S0907444900010040  1
2000 Idriss HT, Naismith JH. TNFα and the TNF receptor superfamily: Structure-function relationship(s) Microscopy Research and Technique. 50: 184-195. PMID 10891884 DOI: 10.1002/1097-0029(20000801)50:3<184::AID-JEMT2>3.0.CO;2-H  1
2000 Giraud MF, Leonard GA, Field RA, Berlind C, Naismith JH. RmlC, the third enzyme of dTDP-L-rhamnose pathway, is a new class of epimerase. Nature Structural Biology. 7: 398-402. PMID 10802738 DOI: 10.1038/75178  1
2000 Allard STM, Giraud MF, Whitfield C, Messner P, Naismith JH. The purification, crystallization and structural elucidation of dTDP-D-glucose 4,6-dehydratase (RmlB), the second enzyme of the dTDP-L-rhamnose synthesis pathway from Salmonella enterica serovar Typhimurium Acta Crystallographica Section D: Biological Crystallography. 56: 222-225. PMID 10666612 DOI: 10.1107/S0907444999016200  1
2000 Naismith JH. Don't let politics put Diamond at risk [4] Nature. 403: 698.  1
1999 Giraud MF, McMiken HJ, Leonard GA, Messner P, Whitfield C, Naismith JH. Overexpression, purification, crystallization and preliminary structural study of dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD), the fourth enzyme of the dTDP-L-rhamnose synthesis pathway, from Salmonella enterica serovar Typhimurium. Acta Crystallographica. Section D, Biological Crystallography. 55: 2043-6. PMID 10666586 DOI: 10.1107/S0907444999012251  1
1999 Buchanan LV, Mehta N, Pocivavsek L, Niranjanakumari S, Toone EJ, Naismith JH. Initiating a structural study of 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli. Acta Crystallographica. Section D, Biological Crystallography. 55: 1946-8. PMID 10531504 DOI: 10.1107/S0907444999011166  1
1999 Moothoo DN, Canan B, Field RA, Naismith JH. Man α1-2 Man α-OMe-concanavalin A complex reveals a balance of forces involved in carbohydrate recognition Glycobiology. 9: 539-545. PMID 10336986 DOI: 10.1093/glycob/9.6.539  1
1999 Giraud MF, Gordon FM, Whitfield C, Messner P, McMahon SA, Naismith JH. Purification, crystallization and preliminary structural studies of dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase (RmlC), the third enzyme of the dTDP-L-rhamnose synthesis pathway, from Salmonella enterica serovar Typhimurium Acta Crystallographica Section D: Biological Crystallography. 55: 706-708. PMID 10089454 DOI: 10.1107/S0907444998015042  1
1999 Moothoo DN, Naismith JH. A general method for co-crystallization of concanavalin a with carbohydrates Acta Crystallographica Section D: Biological Crystallography. 55: 353-355. PMID 10089449  1
1999 McMahon SA, Leonard GA, Buchanan LV, Giraud MF, Naismith JH. Initiating a crystallographic study of UDP-galactopyranose mutase from Escherichia coli. Acta Crystallographica. Section D, Biological Crystallography. 55: 399-402. PMID 10089346 DOI: 10.1107/S0907444998010877  1
1999 Dimick SM, Powell SC, McMahon SA, Moothoo DN, Naismith JH, Toone EJ. On the meaning of affinity: Cluster glycoside effects and concanavalin A Journal of the American Chemical Society. 121: 10286-10296. DOI: 10.1021/ja991729e  1
1998 Moothoo DN, McMahon SA, Dimick SM, Toone EJ, Naismith JH. Crystallization of succinylated concanavalin A bound to a synthetic bivalent ligand and preliminary structural analysis. Acta Crystallographica. Section D, Biological Crystallography. 54: 1023-5. PMID 9757127 DOI: 10.1107/S0907444998003965  1
1998 Giraud MF, Desterro JMP, Naismith JH. Structure of ubiquitin-conjugating enzyme 9 displays significant differences with other ubiquitin-conjugating enzymes which may reflect its specificity for sumo rather than ubiquitin Acta Crystallographica Section D: Biological Crystallography. 54: 891-898. PMID 9757105 DOI: 10.1107/S0907444998002480  1
1998 Singh J, Garber E, Van Vlijmen H, Karpusas M, Hsu YM, Zheng Z, Naismith JH, Thomas D. The role of polar interactions in the molecular recognition of CD40L with its receptor CD40 Protein Science. 7: 1124-1135. PMID 9605317  1
1998 Naismith JH, Sprang SR. Modularity in the TNF-receptor family. Trends in Biochemical Sciences. 23: 74-9. PMID 9538693 DOI: 10.1016/S0968-0004(97)01164-X  1
1998 Moothoo DN, Naismith JH. Concanavalin A distorts the β-GlcNAc-(1→2)-Man linkage of β-GlcNAc-(1→2)-α-Man-(1→3)-[β-GlcNAc-(1→2)-α-Man-(1→6)]-Man upon binding Glycobiology. 8: 173-181. PMID 9451027 DOI: 10.1093/glycob/8.2.173  1
1997 Harrison JA, Kartha KP, Smith SL, Naismith JH, Schenkman S, Field RA. Development of a high through-put spectrophotometric assay to monitor Trypanosoma cruzi trans-sialidase. Biochemical Society Transactions. 25: 424S. PMID 9388651  1
1996 Cooper SJ, Leonard GA, McSweeney SM, Thompson AW, Naismith JH, Qamar S, Plater A, Berry A, Hunter WN. The crystal structure of a class II fructose-1,6-bisphosphate aldolase shows a novel binuclear metal-binding active site embedded in a familiar fold. Structure (London, England : 1993). 4: 1303-15. PMID 8939754  1
1996 Naismith JH, Devine TQ, Kohno T, Sprang SR. Structures of the extracellular domain of the type I tumor necrosis factor receptor. Structure (London, England : 1993). 4: 1251-62. PMID 8939750  1
1996 Naismith JH, Brandhuber BJ, Devine TQ, Sprang SR. Seeing double: crystal structures of the type I TNF receptor. Journal of Molecular Recognition : Jmr. 9: 113-7. PMID 8877801 DOI: 10.1002/(SICI)1099-1352(199603)9:2<113::AID-JMR253>3.0.CO;2-H  1
1996 Naismith JH, Field RA. Structural basis of trimannoside recognition by concanavalin A Journal of Biological Chemistry. 271: 972-976. PMID 8557713 DOI: 10.1074/jbc.271.2.972  1
1995 Naismith JH, Sprang SR. Tumor necrosis factor receptor superfamily. Journal of Inflammation. 47: 1-7. PMID 8913924  1
1995 Naismith JH, Devine TQ, Brandhuber BJ, Sprang SR. Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor. The Journal of Biological Chemistry. 270: 13303-7. PMID 7768931 DOI: 10.1074/jbc.270.22.13303  1
1994 Emmerich C, Helliwell JR, Redshaw M, Naismith JH, Harrop SJ, Raftery J, Kalb AJ, Yariv J, Dauter Z, Wilson KS. High-resolution structures of single-metal-substituted concanavalin A: the Co,Ca-protein at 1.6 A and the Ni,Ca-protein at 2.0 A. Acta Crystallographica. Section D, Biological Crystallography. 50: 749-56. PMID 15299372 DOI: 10.1107/S0907444994002143  1
1994 Naismith JH, Emmerich C, Habash J, Harrop SJ, Helliwell JR, Hunter WN, Raftery J, Kalb AJ, Yariv J. Refined structure of concanavalin A complexed with methyl alpha-D-mannopyranoside at 2.0 A resolution and comparison with the saccharide-free structure. Acta Crystallographica. Section D, Biological Crystallography. 50: 847-58. PMID 15299352 DOI: 10.1107/S0907444994005287  1
1994 Rodseth LE, Brandhuber B, Devine TQ, Eck MJ, Hale K, Naismith JH, Sprang SR. Two crystal forms of the extracellular domain of type I tumor necrosis factor receptor. Journal of Molecular Biology. 239: 332-5. PMID 8196061 DOI: 10.1006/jmbi.1994.1371  1
1993 Naismith JH, Habash J, Harrop S, Helliwell JR, Hunter WN, Wan TC, Weisgerber S, Kalb AJ, Yariv J. Refined structure of cadmium-substituted concanavalin A at 2.0 A resolution. Acta Crystallographica. Section D, Biological Crystallography. 49: 561-71. PMID 15299493 DOI: 10.1107/S0907444993006390  0.6
1993 Zhang Y, Bailey S, Naismith JH, Bond CS, Habash J, McLaughlin P, Papiz MZ, Borges A, Cunningham M, Fairlamb AH, Hunter WN. Trypanosoma cruzi trypanothione reductase: Crystallization, unit cell dimensions and structure solution Journal of Molecular Biology. 232: 1217-1220. PMID 8371273  1
1993 Armstrong EM, Beddoes RL, Calviou LJ, Charnock JM, Collison D, Ertok N, Naismith JH, David Garner C. The chemical nature of amavadin Journal of the American Chemical Society. 115: 807-808.  1
1992 Naismith JH, Ferrara JD, Bailey S, Marshall K, Dauter Z, Wilson KS, Habash J, Harrop SJ, Berry AJ, Hunter WN. Initiating a crystallographic study of a class II fructose-1,6-bisphosphate aldolase. Journal of Molecular Biology. 225: 1137-41. PMID 1613797 DOI: 10.1016/0022-2836(92)90113-X  1
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