| Year |
Citation |
Score |
| 2023 |
Azer N, Trunfio N, Fratz-Berilla EJ, Hong JS, Cullinan J, Faison T, Agarabi CD, Powers DN. Real time on-line amino acid analysis to explore amino acid trends and link to glycosylation outcomes of a model monoclonal antibody. Biotechnology Progress. e3347. PMID 37102501 DOI: 10.1002/btpr.3347 |
0.345 |
|
| 2020 |
Bhirde A, Chikkaveeraiah BV, Venna R, Carley R, Brorson K, Agarabi C. High Performance Size Exclusion Chromatography and High-Throughput Dynamic Light Scattering as Orthogonal Methods to Screen for Aggregation and Stability of Monoclonal Antibody Drug Products. Journal of Pharmaceutical Sciences. PMID 32835703 DOI: 10.1016/J.Xphs.2020.08.013 |
0.344 |
|
| 2020 |
Hong JS, Azer N, Agarabi C, Fratz-Berilla EJ. Primary Clarification of CHO Harvested Cell Culture Fluid using an Acoustic Separator. Journal of Visualized Experiments : Jove. PMID 32478745 DOI: 10.3791/61161 |
0.416 |
|
| 2020 |
Fratz-Berilla EJ, Angart P, Graham RJ, Powers DN, Mohammad A, Kohnhorst C, Faison T, Velugula-Yellela SR, Trunfio N, Agarabi C. Impacts on Product Quality Attributes of Monoclonal Antibodies Produced in CHO Cell Bioreactor Cultures During Intentional Mycoplasma Contamination Events. Biotechnology and Bioengineering. PMID 32436993 DOI: 10.1002/Bit.27436 |
0.487 |
|
| 2020 |
Sha S, Handelman G, Agarabi C, Yoon S. A high-resolution measurement of nucleotide sugars by using ion-pair reverse chromatography and tandem columns. Analytical and Bioanalytical Chemistry. PMID 32300845 DOI: 10.1007/S00216-020-02608-6 |
0.392 |
|
| 2020 |
Xie T, Fang H, Ouyang W, Angart P, Chiang MJ, Bhirde AA, Sheikh F, Lynch P, Shah AB, Patil SM, Chen K, Shen M, Agarabi C, Donnelly RP, Brorson K, et al. The ELISA Detectability and Potency of Pegfilgrastim Decrease in Physiological Conditions: Key Roles for Aggregation and Individual Variability. Scientific Reports. 10: 2476. PMID 32051479 DOI: 10.1038/S41598-020-59346-Z |
0.33 |
|
| 2019 |
Powers DN, Trunfio N, Velugula-Yellela SR, Angart P, Faustino A, Agarabi C. Multivariate data analysis of growth medium trends affecting antibody glycosylation. Biotechnology Progress. e2903. PMID 31487120 DOI: 10.1002/Btpr.2903 |
0.461 |
|
| 2019 |
Fratz-Berilla EJ, Faison T, Kohnhorst CL, Velugula-Yellela SR, Powers DN, Brorson K, Agarabi C. Impacts of intentional mycoplasma contamination on CHO cell bioreactor cultures. Biotechnology and Bioengineering. PMID 31478189 DOI: 10.1002/Bit.27161 |
0.448 |
|
| 2019 |
Powers DN, Wang Y, Fratz-Berilla EJ, Velugula-Yellela SR, Chavez B, Angart P, Trunfio N, Yoon S, Agarabi C. Real-time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody product quality. Biotechnology Progress. e2894. PMID 31425633 DOI: 10.1002/Btpr.2894 |
0.402 |
|
| 2019 |
Velugula-Yellela SR, Powers DN, Angart P, Faustino A, Faison T, Kohnhorst C, Fratz-Berilla EJ, Agarabi CD. Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor System. Journal of Visualized Experiments : Jove. PMID 31107445 DOI: 10.3791/58947 |
0.508 |
|
| 2018 |
Velugula-Yellela SR, Kohnhorst C, Powers DN, Trunfio N, Faustino A, Angart P, Berilla E, Faison T, Agarabi C. Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells. Journal of Visualized Experiments : Jove. PMID 30320757 DOI: 10.3791/58231 |
0.433 |
|
| 2018 |
Fisher AC, Kamga MH, Agarabi C, Brorson K, Lee SL, Yoon S. The Current Scientific and Regulatory Landscape in Advancing Integrated Continuous Biopharmaceutical Manufacturing. Trends in Biotechnology. PMID 30241924 DOI: 10.1016/J.Tibtech.2018.08.008 |
0.387 |
|
| 2018 |
Mohammad A, Agarabi C, Rogstad S, DiCioccio E, Brorson K, Ashraf M, Faustino PJ, Madhavarao CN. An ICP-MS platform for metal content assessment of cell culture media and evaluation of spikes in metal concentration on the quality of an IgG3:κ monoclonal antibody during production. Journal of Pharmaceutical and Biomedical Analysis. 162: 91-100. PMID 30227357 DOI: 10.1016/J.Jpba.2018.09.008 |
0.422 |
|
| 2018 |
Park SY, Reimonn TM, Agarabi C, Brorson K, Yoon S. Metabolic responses and pathway changes of mammalian cells under different culture conditions with media supplementations. Biotechnology Progress. PMID 29464928 DOI: 10.1002/Btpr.2623 |
0.464 |
|
| 2018 |
Powers DN, Velugula-Yellela SR, Trunfio N, Angart P, Faustino A, Agarabi C. Automated Microbioreactors and the Characterization of Media Dependent Changes in Antibody Product Glycosylation and Aglycosylation Journal of Glycobiology. 7: 1-9. DOI: 10.4172/2168-958X.1000133 |
0.47 |
|
| 2017 |
Velugula-Yellela SR, Williams A, Trunfio N, Hsu CJ, Chavez B, Yoon S, Agarabi C. Impact of media and antifoam selection on monoclonal antibody production and quality using a high throughput micro-bioreactor system. Biotechnology Progress. PMID 29086492 DOI: 10.1002/Btpr.2575 |
0.469 |
|
| 2017 |
Trunfio N, Lee H, Starkey J, Agarabi C, Liu J, Yoon S. Characterization of Mammalian Cell Culture Raw Materials by Combining Spectroscopy and Chemometrics. Biotechnology Progress. PMID 28393480 DOI: 10.1002/Btpr.2480 |
0.391 |
|
| 2017 |
Williams A, Read EK, Agarabi CD, Lute S, Brorson KA. Automated 2D-HPLC method for characterization of protein aggregation with in-line fraction collection device. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1046: 122-130. PMID 28178596 DOI: 10.1016/J.Jchromb.2017.01.021 |
0.438 |
|
| 2017 |
Wang J, Johnson S, Brown M, Lute S, Agarabi C, Dabrazhynetskaya A, Chizhikov V, Brorson K. Mycoplasma clearance and risk analysis in a model bioprocess. Pda Journal of Pharmaceutical Science and Technology. PMID 28089962 DOI: 10.5731/Pdajpst.2016.007054 |
0.405 |
|
| 2016 |
Agarabi CD, Chavez BK, Lute SC, Read EK, Rogstad S, Awotwe-Otoo D, Brown MR, Boyne MT, Brorson KA. "Exploring the Linkage Between Cell Culture Process Parameters and Downstream Processing Utilizing a Plackett-Burman Design for a Model Monoclonal Antibody." Biotechnology Progress. PMID 27813291 DOI: 10.1002/Btpr.2402 |
0.499 |
|
| 2016 |
Bhatia H, Read E, Agarabi C, Brorson K, Lute S, Yoon S. Hybridoma cell-culture and glycan profile dataset at various bioreactor conditions. Data in Brief. 9: 676-678. PMID 27790631 DOI: 10.1016/J.Dib.2016.10.003 |
0.32 |
|
| 2016 |
Bhatia H, Read E, Agarabi C, Brorson K, Lute S, Yoon S. A Design Space Exploration for Control of Critical Quality Attributes of mAb. International Journal of Pharmaceutics. PMID 27575657 DOI: 10.1016/J.Ijpharm.2016.08.046 |
0.366 |
|
| 2016 |
Reimonn TM, Park SY, Agarabi C, Brorson K, Yoon S. Effect of amino acid supplementation on titer and glycosylation distribution in hybridoma cell cultures - Systems biology based interpretation using genome-scale metabolic flux balance model and multivariate data analysis. Biotechnology Progress. PMID 27452371 DOI: 10.1002/Btpr.2335 |
0.406 |
|
| 2016 |
Chavez BK, Agarabi CD, Read EK, Boyne Ii MT, Khan MA, Brorson KA. Improved Stability of a Model IgG3 by DoE-Based Evaluation of Buffer Formulations. Biomed Research International. 2016: 2074149. PMID 27042659 DOI: 10.1155/2016/2074149 |
0.387 |
|
| 2016 |
Sha S, Agarabi C, Brorson K, Lee DY, Yoon S. N-Glycosylation Design and Control of Therapeutic Monoclonal Antibodies. Trends in Biotechnology. PMID 27016033 DOI: 10.1016/J.Tibtech.2016.02.013 |
0.392 |
|
| 2015 |
Rathore AS, Kumar Singh S, Pathak M, Read EK, Brorson KA, Agarabi CD, Khan M. Fermentanomics: Relating quality attributes of a monoclonal antibody to cell culture process variables and raw materials using multivariate data analysis. Biotechnology Progress. 31: 1586-99. PMID 26280800 DOI: 10.1002/Btpr.2155 |
0.502 |
|
| 2015 |
Awotwe-Otoo D, Agarabi C, Read EK, Lute S, Brorson KA, Khan MA. Product and process understanding to relate the effect of freezing method on glycation and aggregation of lyophilized monoclonal antibody formulations. International Journal of Pharmaceutics. 490: 341-50. PMID 25835267 DOI: 10.1016/J.Ijpharm.2015.03.056 |
0.38 |
|
| 2015 |
Agarabi CD, Schiel JE, Lute SC, Chavez BK, Boyne MT, Brorson KA, Khan MA, Read EK. Bioreactor process parameter screening utilizing a Plackett-Burman design for a model monoclonal antibody. Journal of Pharmaceutical Sciences. 104: 1919-28. PMID 25762022 DOI: 10.1002/Jps.24420 |
0.509 |
|
| 2015 |
Rathore AS, Kumar Singh S, Pathak M, Read EK, Brorson KA, Agarabi CD, Khan M. Fermentanomics: Relating quality attributes of a monoclonal antibody to cell culture process variables and raw materials using multivariate data analysis Biotechnology Progress. DOI: 10.1002/btpr.2155 |
0.356 |
|
| 2014 |
Awotwe−Otoo D, Agarabi C, Khan MA. An Integrated Process Analytical Technology (PAT) Approach to Monitoring the Effect of Supercooling on Lyophilization Product and Process Parameters of Model Monoclonal Antibody Formulations Journal of Pharmaceutical Sciences. 103: 2042-2052. PMID 24840395 DOI: 10.1002/Jps.24005 |
0.399 |
|
| 2014 |
Madhavarao CN, Agarabi CD, Wong L, Müller-Loennies S, Braulke T, Khan M, Anderson H, Johnson GR. Evaluation of butyrate-induced production of a mannose-6-phosphorylated therapeutic enzyme using parallel bioreactors. Biotechnology and Applied Biochemistry. 61: 184-92. PMID 24033810 DOI: 10.1002/Bab.1151 |
0.364 |
|
| 2013 |
Awotwe-Otoo D, Agarabi C, Read EK, Lute S, Brorson KA, Khan MA, Shah RB. Impact of controlled ice nucleation on process performance and quality attributes of a lyophilized monoclonal antibody. International Journal of Pharmaceutics. 450: 70-8. PMID 23618961 DOI: 10.1016/J.Ijpharm.2013.04.041 |
0.344 |
|
| 2013 |
Read EK, Bradley SA, Smitka TA, Agarabi CD, Lute SC, Brorson KA. Fermentanomics informed amino acid supplementation of an antibody producing mammalian cell culture. Biotechnology Progress. 29: 745-53. PMID 23606649 DOI: 10.1002/Btpr.1728 |
0.442 |
|
| 2012 |
Awotwe-Otoo D, Agarabi C, Wu GK, Casey E, Read E, Lute S, Brorson KA, Khan MA, Shah RB. Quality by design: impact of formulation variables and their interactions on quality attributes of a lyophilized monoclonal antibody. International Journal of Pharmaceutics. 438: 167-75. PMID 22944306 DOI: 10.1016/J.Ijpharm.2012.08.033 |
0.44 |
|
| 2012 |
Awotwe-Otoo D, Agarabi C, Faustino PJ, Habib MJ, Lee S, Khan MA, Shah RB. Application of quality by design elements for the development and optimization of an analytical method for protamine sulfate. Journal of Pharmaceutical and Biomedical Analysis. 62: 61-7. PMID 22316620 DOI: 10.1016/J.Jpba.2012.01.002 |
0.335 |
|
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