Year |
Citation |
Score |
2014 |
Smith CC, Martin SC, Sugunan K, Russek SJ, Gibbs TT, Farb DH. A role for picomolar concentrations of pregnenolone sulfate in synaptic activity-dependent Ca2+ signaling and CREB activation. Molecular Pharmacology. 86: 390-8. PMID 25057049 DOI: 10.1124/Mol.114.094128 |
0.72 |
|
2014 |
Smith CC, Gibbs TT, Farb DH. Pregnenolone sulfate as a modulator of synaptic plasticity. Psychopharmacology. 231: 3537-56. PMID 24997854 DOI: 10.1007/S00213-014-3643-X |
0.639 |
|
2013 |
Oblak A, Gibbs TT, Blatt GJ. Reduced serotonin receptor subtypes in a limbic and a neocortical region in autism. Autism Research : Official Journal of the International Society For Autism Research. 6: 571-83. PMID 23894004 DOI: 10.1002/Aur.1317 |
0.302 |
|
2013 |
Kostakis E, Smith C, Jang MK, Martin SC, Richards KG, Russek SJ, Gibbs TT, Farb DH. The neuroactive steroid pregnenolone sulfate stimulates trafficking of functional N-methyl D-aspartate receptors to the cell surface via a noncanonical, G protein, and Ca2+-dependent mechanism. Molecular Pharmacology. 84: 261-74. PMID 23716622 DOI: 10.1124/Mol.113.085696 |
0.777 |
|
2011 |
Kostakis E, Jang MK, Russek SJ, Gibbs TT, Farb DH. A steroid modulatory domain in NR2A collaborates with NR1 exon-5 to control NMDAR modulation by pregnenolone sulfate and protons. Journal of Neurochemistry. 119: 486-96. PMID 21883211 DOI: 10.1111/J.1471-4159.2011.07442.X |
0.786 |
|
2011 |
Oblak AL, Gibbs TT, Blatt GJ. Reduced GABAA receptors and benzodiazepine binding sites in the posterior cingulate cortex and fusiform gyrus in autism. Brain Research. 1380: 218-28. PMID 20858465 DOI: 10.1016/J.Brainres.2010.09.021 |
0.408 |
|
2010 |
Oblak AL, Gibbs TT, Blatt GJ. Decreased GABA(B) receptors in the cingulate cortex and fusiform gyrus in autism. Journal of Neurochemistry. 114: 1414-23. PMID 20557420 DOI: 10.1111/J.1471-4159.2010.06858.X |
0.484 |
|
2009 |
Oblak A, Gibbs TT, Blatt GJ. Decreased GABAA receptors and benzodiazepine binding sites in the anterior cingulate cortex in autism. Autism Research : Official Journal of the International Society For Autism Research. 2: 205-19. PMID 19650112 DOI: 10.1002/Aur.88 |
0.49 |
|
2009 |
Berezhnoy D, Gibbs TT, Farb DH. Docking of 1,4-benzodiazepines in the alpha1/gamma2 GABA(A) receptor modulator site. Molecular Pharmacology. 76: 440-50. PMID 19483108 DOI: 10.1124/Mol.109.054650 |
0.705 |
|
2008 |
Sadri-Vakili G, Janis GC, Pierce RC, Gibbs TT, Farb DH. Nanomolar concentrations of pregnenolone sulfate enhance striatal dopamine overflow in vivo. The Journal of Pharmacology and Experimental Therapeutics. 327: 840-5. PMID 18772319 DOI: 10.1124/Jpet.108.143958 |
0.814 |
|
2008 |
Whittaker MT, Gibbs TT, Farb DH. Pregnenolone sulfate induces NMDA receptor dependent release of dopamine from synaptic terminals in the striatum. Journal of Neurochemistry. 107: 510-21. PMID 18710414 DOI: 10.1111/J.1471-4159.2008.05627.X |
0.787 |
|
2008 |
Berezhnoy D, Gravielle MC, Downing S, Kostakis E, Basile AS, Skolnick P, Gibbs TT, Farb DH. Pharmacological Properties of DOV 315,090, an ocinaplon metabolite. Bmc Pharmacology. 8: 11. PMID 18554397 DOI: 10.1186/1471-2210-8-11 |
0.759 |
|
2007 |
Guptill JT, Booker AB, Gibbs TT, Kemper TL, Bauman ML, Blatt GJ. [3H]-flunitrazepam-labeled benzodiazepine binding sites in the hippocampal formation in autism: a multiple concentration autoradiographic study. Journal of Autism and Developmental Disorders. 37: 911-20. PMID 17019626 DOI: 10.1007/S10803-006-0226-7 |
0.417 |
|
2007 |
Ratner MH, Desbien SC, Pierce RC, Gibbs TT. Pregnanolone Hemisuccinate Inhibits Priming-Induced Reinstatement of Cocaine Seeking in Rats The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.6.A779 |
0.577 |
|
2006 |
Gibbs TT, Russek SJ, Farb DH. Sulfated steroids as endogenous neuromodulators. Pharmacology, Biochemistry, and Behavior. 84: 555-67. PMID 17023038 DOI: 10.1016/J.Pbb.2006.07.031 |
0.774 |
|
2006 |
Popik P, Kostakis E, Krawczyk M, Nowak G, Szewczyk B, Krieter P, Chen Z, Russek SJ, Gibbs TT, Farb DH, Skolnick P, Lippa AS, Basile AS. The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors. The Journal of Pharmacology and Experimental Therapeutics. 319: 1244-52. PMID 16971504 DOI: 10.1124/Jpet.106.107201 |
0.798 |
|
2005 |
Downing SS, Lee YT, Farb DH, Gibbs TT. Benzodiazepine modulation of partial agonist efficacy and spontaneously active GABA(A) receptors supports an allosteric model of modulation. British Journal of Pharmacology. 145: 894-906. PMID 15912137 DOI: 10.1038/Sj.Bjp.0706251 |
0.816 |
|
2005 |
Lippa A, Czobor P, Stark J, Beer B, Kostakis E, Gravielle M, Bandyopadhyay S, Russek SJ, Gibbs TT, Farb DH, Skolnick P. Selective anxiolysis produced by ocinaplon, a GABA(A) receptor modulator. Proceedings of the National Academy of Sciences of the United States of America. 102: 7380-5. PMID 15870187 DOI: 10.1073/Pnas.0502579102 |
0.771 |
|
2003 |
Sadri-Vakili G, Johnson DW, Janis GC, Gibbs TT, Pierce RC, Farb DH. Inhibition of NMDA-induced striatal dopamine release and behavioral activation by the neuroactive steroid 3alpha-hydroxy-5beta-pregnan-20-one hemisuccinate. Journal of Neurochemistry. 86: 92-101. PMID 12807429 DOI: 10.1046/J.1471-4159.2003.01814.X |
0.788 |
|
2002 |
Malayev A, Gibbs TT, Farb DH. Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids. British Journal of Pharmacology. 135: 901-9. PMID 11861317 DOI: 10.1038/Sj.Bjp.0704543 |
0.719 |
|
2001 |
Lyons HR, Land MB, Gibbs TT, Farb DH. Distinct signal transduction pathways for GABA-induced GABA(A) receptor down-regulation and uncoupling in neuronal culture: a role for voltage-gated calcium channels. Journal of Neurochemistry. 78: 1114-26. PMID 11553685 DOI: 10.1046/J.1471-4159.2001.00501.X |
0.701 |
|
2000 |
Gibbs TT, Farb DH. Dueling enigmas: neurosteroids and sigma receptors in the limelight. Science's Stke : Signal Transduction Knowledge Environment. 2000: pe1. PMID 11752623 DOI: 10.1126/Stke.2000.60.Pe1 |
0.707 |
|
2000 |
Weaver CE, Land MB, Purdy RH, Richards KG, Gibbs TT, Farb DH. Geometry and charge determine pharmacological effects of steroids on N-methyl-D-aspartate receptor-induced Ca(2+) accumulation and cell death. The Journal of Pharmacology and Experimental Therapeutics. 293: 747-54. PMID 10869372 |
0.672 |
|
2000 |
Lyons HR, Gibbs TT, Farb DH. Turnover and down-regulation of GABA(A) receptor alpha1, beta2S, and gamma1 subunit mRNAs by neurons in culture. Journal of Neurochemistry. 74: 1041-8. PMID 10693935 DOI: 10.1046/J.1471-4159.2000.0741041.X |
0.714 |
|
1999 |
Park-Chung M, Malayev A, Purdy RH, Gibbs TT, Farb DH. Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites. Brain Research. 830: 72-87. PMID 10350561 DOI: 10.1016/S0006-8993(99)01381-5 |
0.719 |
|
1998 |
Yaghoubi N, Malayev A, Russek SJ, Gibbs TT, Farb DH. Neurosteroid modulation of recombinant ionotropic glutamate receptors. Brain Research. 803: 153-60. PMID 9729352 DOI: 10.1016/S0006-8993(98)00644-1 |
0.782 |
|
1998 |
Weaver CE, Wu FS, Gibbs TT, Farb DH. Pregnenolone sulfate exacerbates NMDA-induced death of hippocampal neurons. Brain Research. 803: 129-36. PMID 9729331 DOI: 10.1016/S0006-8993(98)00640-4 |
0.673 |
|
1997 |
Park-Chung M, Wu FS, Purdy RH, Malayev AA, Gibbs TT, Farb DH. Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids. Molecular Pharmacology. 52: 1113-23. PMID 9396781 DOI: 10.1124/Mol.52.6.1113 |
0.72 |
|
1997 |
Weaver CE, Park-Chung M, Gibbs TT, Farb DH. 17beta-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors. Brain Research. 761: 338-41. PMID 9252035 DOI: 10.1016/S0006-8993(97)00449-6 |
0.673 |
|
1997 |
Weaver CE, Park-Chung M, Gibbs TT, Farb DH. 17β-estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors Brain Research. 761: 338-341. DOI: 10.1016/S0006-8993(97)00449-6 |
0.634 |
|
1996 |
Friedman LK, Gibbs TT, Farb DH. gamma-aminobutyric acidA receptor regulation: heterologous uncoupling of modulatory site interactions induced by chronic steroid, barbiturate, benzodiazepine, or GABA treatment in culture. Brain Research. 707: 100-9. PMID 8866718 DOI: 10.1016/0006-8993(95)01226-5 |
0.712 |
|
1994 |
Gyenes M, Wang Q, Gibbs TT, Farb DH. Phosphorylation factors control neurotransmitter and neuromodulator actions at the gamma-aminobutyric acid type A receptor. Molecular Pharmacology. 46: 542-9. PMID 7935336 |
0.703 |
|
1993 |
Friedman L, Gibbs TT, Farb DH. Gamma-aminobutyric acidA receptor regulation: chronic treatment with pregnanolone uncouples allosteric interactions between steroid and benzodiazepine recognition sites. Molecular Pharmacology. 44: 191-7. PMID 8393520 |
0.625 |
|
1993 |
Wu FS, Gibbs TT, Farb DH. Dual activation of GABAA and glycine receptors by beta-alanine: inverse modulation by progesterone and 5 alpha-pregnan-3 alpha-ol-20-one. European Journal of Pharmacology. 246: 239-46. PMID 8223947 DOI: 10.1016/0922-4106(93)90037-A |
0.713 |
|
1992 |
Farb DH, Gibbs TT, Wu FS, Gyenes M, Friedman L, Russek SJ. Steroid modulation of amino acid neurotransmitter receptors. Advances in Biochemical Psychopharmacology. 47: 119-31. PMID 1324566 |
0.736 |
|
1991 |
Celentano JJ, Gyenes M, Gibbs TT, Farb DH. Negative modulation of the gamma-aminobutyric acid response by extracellular zinc. Molecular Pharmacology. 40: 766-73. PMID 1658609 |
0.669 |
|
1991 |
Wu FS, Gibbs TT, Farb DH. Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor. Molecular Pharmacology. 40: 333-6. PMID 1654510 |
0.688 |
|
1990 |
Wu FS, Gibbs TT, Farb DH. Inverse modulation of gamma-aminobutyric acid- and glycine-induced currents by progesterone. Molecular Pharmacology. 37: 597-602. PMID 2338942 |
0.696 |
|
1990 |
Borden LA, Gibbs TT. Flunitrazepam photoaffinity labeling of the GABA(A) receptor reduces inhibition of [3H]Ro15-4513 binding by GABA. European Journal of Pharmacology. 188: 391-7. PMID 2164940 DOI: 10.1016/0922-4106(90)90199-8 |
0.427 |
|
1990 |
Farrant M, Gibbs TT, Farb DH. Molecular and cellular mechanisms of GABA/benzodiazepine-receptor regulation: electrophysiological and biochemical studies. Neurochemical Research. 15: 175-91. PMID 2159123 DOI: 10.1007/Bf00972208 |
0.79 |
|
1990 |
Roca DJ, Schiller GD, Friedman L, Rozenberg I, Gibbs TT, Farb DH. gamma-Aminobutyric acidA receptor regulation in culture: altered allosteric interactions following prolonged exposure to benzodiazepines, barbiturates, and methylxanthines. Molecular Pharmacology. 37: 710-9. PMID 1692607 |
0.715 |
|
1989 |
Czajkowski C, Gibbs TT, Farb DH. Transmembrane topology of the gamma-aminobutyric acidA/benzodiazepine receptor: subcellular distribution and allosteric coupling determined in situ. Molecular Pharmacology. 35: 75-84. PMID 2536471 |
0.78 |
|
1988 |
Celentano JJ, Gibbs TT, Farb DH. Ethanol potentiates GABA- and glycine-induced chloride currents in chick spinal cord neurons. Brain Research. 455: 377-80. PMID 2900060 DOI: 10.1016/0006-8993(88)90098-4 |
0.638 |
|
1988 |
Gibbs TT, Mierlak D, Gyenes M, Celentano JJ, Farb DH. Functional and structural correlates of GABA receptor modulation. Advances in Biochemical Psychopharmacology. 45: 95-107. PMID 2845741 |
0.692 |
|
1987 |
Borden LA, Gibbs TT, Farb DH. Identification, characterization, and developmental regulation of embryonic benzodiazepine binding sites. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 1902-10. PMID 3598653 DOI: 10.1523/Jneurosci.07-06-01902.1987 |
0.647 |
|
1986 |
Farb DH, Czajkowski CM, Borden LA, Schiller GD, Gibbs TT. Turnover of the benzodiazepine/gamma-aminobutyric acid receptor complex determined in situ. Advances in Biochemical Psychopharmacology. 41: 51-66. PMID 3017074 |
0.756 |
|
1986 |
Gibbs TT, Chan CY, Farb DH. Correlative binding and electrophysiological studies of the photoaffinity-labeled benzodiazepine receptor Annals of the New York Academy of Sciences. 183-185. DOI: 10.1111/J.1749-6632.1986.Tb21539.X |
0.664 |
|
1985 |
Gibbs TT, Chan CY, Czajkowski CM, Farb DH. Benzodiazepine receptor photoaffinity labeling: correlation of function with binding. European Journal of Pharmacology. 110: 171-80. PMID 2985408 DOI: 10.1016/0014-2999(85)90209-2 |
0.786 |
|
1984 |
Farb DH, Borden LA, Chan CY, Czajkowski CM, Gibbs TT, Schiller GD. Modulation of neuronal function through benzodiazepine receptors: biochemical and electrophysiological studies of neurons in primary monolayer cell culture. Annals of the New York Academy of Sciences. 435: 1-31. PMID 6099704 DOI: 10.1111/J.1749-6632.1984.Tb13737.X |
0.74 |
|
1983 |
Chan CY, Gibbs TT, Borden LA, Farb DH. Multiple embryonic benzodiazepine binding sites: evidence for functionality. Life Sciences. 33: 2061-9. PMID 6316055 DOI: 10.1016/0024-3205(83)90329-6 |
0.68 |
|
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