Michael Blaber - Publications

Affiliations: 
Florida State University, Tallahassee, FL, United States 
Area:
Biochemistry

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Okazaki N, Blaber M, Kuroki R, Tamada T. Crystal structure of glycosyltrehalose synthase from Sulfolobus shibatae DSM5389. Acta Crystallographica. Section F, Structural Biology Communications. 74: 741-746. PMID 30387780 DOI: 10.1107/S2053230X1801453X  1
2018 Cogan NG, Mellers AP, Patel BN, Powell BD, Aggarwal M, Harper KM, Blaber M. A Mathematical Model for the Determination of Mouse Excisional Wound Healing Parameters from Photographic Data. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. PMID 29663583 DOI: 10.1111/wrr.12634  1
2018 Angalakurthi SK, Tenorio CA, Blaber M, Middaugh CR. Investigating the Dynamics and Polyanion Binding Sites of Fibroblast Growth Factor-1 Using Hydrogen-Deuterium Exchange Mass Spectrometry. Protein Science : a Publication of the Protein Society. PMID 29645318 DOI: 10.1002/pro.3423  1
2017 Longo LM, Gao Y, Tenorio CA, Wang G, Paravastu AK, Blaber M. The Folding Nucleus Structure Persists in Thermally-Aggregated FGF-1. Protein Science : a Publication of the Protein Society. PMID 29076579 DOI: 10.1002/pro.3332  1
2016 Xia X, Kumru OS, Blaber SI, Middaugh CR, Li L, Ornitz DM, Suh JM, Atkins AR, Downes M, Evans RM, Tenorio CA, Bienkiewicz E, Blaber M. An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities. Journal of Pharmaceutical Sciences. 105: 3507-3519. PMID 27773526 DOI: 10.1016/j.xphs.2016.09.005  1
2016 Blaber M. Myths and Verities in Protein Folding Theories. By Arieh Ben-Naim. World Scientific, 2015. Pp. 448. Hardback. Price GBP 45.00. ISBN 978-981-4725-98-9. Acta Crystallographica. Section D, Structural Biology. 72: 1076-80. PMID 27599740 DOI: 10.1107/S2059798316013140  0.01
2016 Arai S, Shibazaki C, Adachi M, Honjo E, Tamada T, Maeda Y, Tahara T, Kato T, Miyazaki H, Blaber M, Kuroki R. An insight into the thermodynamic characteristics of human thrombopoietin complexation with TN1 antibody. Protein Science : a Publication of the Protein Society. 25: 1786-96. PMID 27419667 DOI: 10.1002/pro.2985  1
2016 Xia X, Kumru OS, Blaber SI, Middaugh CR, Li L, Ornitz DM, Sutherland MA, Tenorio CA, Blaber M. Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application. Journal of Pharmaceutical Sciences. 105: 1444-53. PMID 27019961 DOI: 10.1016/j.xphs.2016.02.010  1
2016 Xia X, Longo LM, Sutherland MA, Blaber M. Evolution of a protein folding nucleus. Protein Science : a Publication of the Protein Society. 25: 1227-40. PMID 26610273 DOI: 10.1002/pro.2848  1
2015 Assis DM, Juliano L, Paschoalin T, Kouyoumdjian M, Calixto JB, Santos RA, Pertinhez TA, Gauthier F, Moreau T, Blaber M, Juliano MA. Pharmacological Activities and Hydrolysis by Peptidases of [Phospho-Ser(6)]-Bradykinin (pS(6)-BK). Biochemical Pharmacology. 97: 203-14. PMID 26235942 DOI: 10.1016/j.bcp.2015.07.033  1
2015 Blaber SI, Diaz J, Blaber M. Accelerated healing in NONcNZO10/LtJ type 2 diabetic mice by FGF-1. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 23: 538-49. PMID 25891187 DOI: 10.1111/wrr.12305  1
2015 Arai S, Yonezawa Y, Okazaki N, Matsumoto F, Shibazaki C, Shimizu R, Yamada M, Adachi M, Tamada T, Kawamoto M, Tokunaga H, Ishibashi M, Blaber M, Tokunaga M, Kuroki R. Structure of a highly acidic β-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs(+)-selective binding site. Acta Crystallographica. Section D, Biological Crystallography. 71: 541-54. PMID 25760604 DOI: 10.1107/S1399004714027734  1
2015 Hiromoto T, Honjo E, Noda N, Tamada T, Kazuma K, Suzuki M, Blaber M, Kuroki R. Structural basis for acceptor-substrate recognition of UDP-glucose: anthocyanidin 3-O-glucosyltransferase from Clitoria ternatea. Protein Science : a Publication of the Protein Society. 24: 395-407. PMID 25556637 DOI: 10.1002/pro.2630  1
2015 Oliveira JR, Bertolin TC, Andrade D, Oliveira LC, Kondo MY, Santos JA, Blaber M, Juliano L, Severino B, Caliendo G, Santagada V, Juliano MA. Specificity studies on Kallikrein-related peptidase 7 (KLK7) and effects of osmolytes and glycosaminoglycans on its peptidase activity. Biochimica Et Biophysica Acta. 1854: 73-83. PMID 25448018 DOI: 10.1016/j.bbapap.2014.10.018  1
2015 Xia X, Longo LM, Blaber M. Mutation choice to eliminate buried free cysteines in protein therapeutics. Journal of Pharmaceutical Sciences. 104: 566-76. PMID 25312595 DOI: 10.1002/jps.24188  1
2015 Longo LM, Tenorio CA, Kumru OS, Middaugh CR, Blaber M. A single aromatic core mutation converts a designed "primitive" protein from halophile to mesophile folding. Protein Science : a Publication of the Protein Society. 24: 27-37. PMID 25297559 DOI: 10.1002/pro.2580  1
2014 Longo LM, Kumru OS, Middaugh CR, Blaber M. Evolution and design of protein structure by folding nucleus symmetric expansion. Structure (London, England : 1993). 22: 1377-84. PMID 25242458 DOI: 10.1016/j.str.2014.08.008  1
2014 Longo LM, Blaber M. Symmetric protein architecture in protein design: top-down symmetric deconstruction. Methods in Molecular Biology (Clifton, N.J.). 1216: 161-82. PMID 25213415 DOI: 10.1007/978-1-4939-1486-9_8  1
2014 Oliveira JP, Freitas RF, Melo LS, Barros TG, Santos JA, Juliano MA, Pinheiro S, Blaber M, Juliano L, Muri EM, Puzer L. Isomannide-based peptidomimetics as inhibitors for human tissue kallikreins 5 and 7. Acs Medicinal Chemistry Letters. 5: 128-32. PMID 24900785 DOI: 10.1021/ml4003698  1
2014 Arai S, Yonezawa Y, Ishibashi M, Matsumoto F, Adachi M, Tamada T, Tokunaga H, Blaber M, Tokunaga M, Kuroki R. Structural characteristics of alkaline phosphatase from the moderately halophilic bacterium Halomonas sp. 593. Acta Crystallographica. Section D, Biological Crystallography. 70: 811-20. PMID 24598750 DOI: 10.1107/S1399004713033609  1
2014 Longo LM, Blaber M. Prebiotic protein design supports a halophile origin of foldable proteins. Frontiers in Microbiology. 4: 418. PMID 24432016 DOI: 10.3389/fmicb.2013.00418  1
2013 Phipps HW, Longo LM, Blaber SI, Blaber M, Vanlandingham JW. Kallikrein-related peptidase 6: a biomarker for traumatic brain injury in the rat. Brain Injury. 27: 1698-706. PMID 24266798 DOI: 10.3109/02699052.2013.823563  1
2013 Longo LM, Lee J, Tenorio CA, Blaber M. Alternative folding nuclei definitions facilitate the evolution of a symmetric protein fold from a smaller peptide motif. Structure (London, England : 1993). 21: 2042-50. PMID 24139990 DOI: 10.1016/j.str.2013.09.003  1
2013 Radulovic M, Yoon H, Larson N, Wu J, Linbo R, Burda JE, Diamandis EP, Blaber SI, Blaber M, Fehlings MG, Scarisbrick IA. Kallikrein cascades in traumatic spinal cord injury: in vitro evidence for roles in axonopathy and neuron degeneration. Journal of Neuropathology and Experimental Neurology. 72: 1072-89. PMID 24128681 DOI: 10.1097/NEN.0000000000000007  1
2013 Adachi M, Shimizu R, Kuroki R, Blaber M. Creation and structure determination of an artificial protein with three complete sequence repeats. Journal of Synchrotron Radiation. 20: 953-7. PMID 24121347 DOI: 10.1107/S0909049513022164  1
2013 Yoon H, Radulovic M, Wu J, Blaber SI, Blaber M, Fehlings MG, Scarisbrick IA. Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity. Journal of Neurochemistry. 127: 283-98. PMID 23647384 DOI: 10.1111/jnc.12293  1
2013 de Souza LR, M Melo P, Paschoalin T, Carmona AK, Kondo M, Hirata IY, Blaber M, Tersariol I, Takatsuka J, Juliano MA, Juliano L, Gomes RA, Puzer L. Human tissue kallikreins 3 and 5 can act as plasminogen activator releasing active plasmin. Biochemical and Biophysical Research Communications. 433: 333-7. PMID 23500465 DOI: 10.1016/j.bbrc.2013.03.001  1
2013 Longo LM, Lee J, Blaber M. Simplified protein design biased for prebiotic amino acids yields a foldable, halophilic protein. Proceedings of the National Academy of Sciences of the United States of America. 110: 2135-9. PMID 23341608 DOI: 10.1073/pnas.1219530110  1
2013 Drucker KL, Paulsen AR, Giannini C, Decker PA, Blaber SI, Blaber M, Uhm JH, O'Neill BP, Jenkins RB, Scarisbrick IA. Clinical significance and novel mechanism of action of kallikrein 6 in glioblastoma. Neuro-Oncology. 15: 305-18. PMID 23307575 DOI: 10.1093/neuonc/nos313  1
2013 Yoon H, Blaber SI, Li W, Scarisbrick IA, Blaber M. Activation profiles of human kallikrein-related peptidases by matrix metalloproteinases. Biological Chemistry. 394: 137-47. PMID 23241590 DOI: 10.1515/hsz-2012-0249  1
2012 Xia X, Babcock JP, Blaber SI, Harper KM, Blaber M. Pharmacokinetic properties of 2nd-generation fibroblast growth factor-1 mutants for therapeutic application. Plos One. 7: e48210. PMID 23133616 DOI: 10.1371/journal.pone.0048210  1
2012 Longo L, Lee J, Blaber M. Experimental support for the foldability-function tradeoff hypothesis: segregation of the folding nucleus and functional regions in fibroblast growth factor-1. Protein Science : a Publication of the Protein Society. 21: 1911-20. PMID 23047594 DOI: 10.1002/pro.2175  1
2012 Freitas RF, Teixeira TS, Barros TG, Santos JA, Kondo MY, Juliano MA, Juliano L, Blaber M, Antunes OA, Abrahão O, Pinheiro S, Muri EM, Puzer L. Isomannide derivatives as new class of inhibitors for human kallikrein 7. Bioorganic & Medicinal Chemistry Letters. 22: 6072-5. PMID 22959247 DOI: 10.1016/j.bmcl.2012.08.047  1
2012 Blaber M, Lee J, Longo L. Emergence of symmetric protein architecture from a simple peptide motif: evolutionary models. Cellular and Molecular Life Sciences : Cmls. 69: 3999-4006. PMID 22790181 DOI: 10.1007/s00018-012-1077-3  1
2012 Longo LM, Blaber M. Protein design at the interface of the pre-biotic and biotic worlds. Archives of Biochemistry and Biophysics. 526: 16-21. PMID 22772066 DOI: 10.1016/j.abb.2012.06.009  1
2012 Shoyama Y, Tamada T, Kurihara K, Takeuchi A, Taura F, Arai S, Blaber M, Shoyama Y, Morimoto S, Kuroki R. Structure and function of ∆1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa. Journal of Molecular Biology. 423: 96-105. PMID 22766313 DOI: 10.1016/j.jmb.2012.06.030  1
2012 Blaber M, Lee J. Designing proteins from simple motifs: opportunities in Top-Down Symmetric Deconstruction. Current Opinion in Structural Biology. 22: 442-50. PMID 22726756 DOI: 10.1016/j.sbi.2012.05.008  1
2012 Scarisbrick IA, Radulovic M, Burda JE, Larson N, Blaber SI, Giannini C, Blaber M, Vandell AG. Kallikrein 6 is a novel molecular trigger of reactive astrogliosis. Biological Chemistry. 393: 355-67. PMID 22505518 DOI: 10.1515/hsz-2011-0241  1
2012 Scarisbrick IA, Yoon H, Panos M, Larson N, Blaber SI, Blaber M, Rodriguez M. Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis. Brain Pathology (Zurich, Switzerland). 22: 709-22. PMID 22335454 DOI: 10.1111/j.1750-3639.2012.00577.x  1
2012 Okazaki N, Tamada T, Feese MD, Kato M, Miura Y, Komeda T, Kobayashi K, Kondo K, Blaber M, Kuroki R. Substrate recognition mechanism of a glycosyltrehalose trehalohydrolase from Sulfolobus solfataricus KM1. Protein Science : a Publication of the Protein Society. 21: 539-52. PMID 22334583 DOI: 10.1002/pro.2039  1
2012 Arai S, Yonezawa Y, Okazaki N, Matsumoto F, Tamada T, Tokunaga H, Ishibashi M, Blaber M, Tokunaga M, Kuroki R. A structural mechanism for dimeric to tetrameric oligomer conversion in Halomonas sp. nucleoside diphosphate kinase. Protein Science : a Publication of the Protein Society. 21: 498-510. PMID 22275000 DOI: 10.1002/pro.2032  1
2012 Alsenaidy MA, Wang T, Kim JH, Joshi SB, Lee J, Blaber M, Volkin DB, Middaugh CR. An empirical phase diagram approach to investigate conformational stability of "second-generation" functional mutants of acidic fibroblast growth factor-1. Protein Science : a Publication of the Protein Society. 21: 418-32. PMID 22113934 DOI: 10.1002/pro.2008  1
2011 Teixeira TS, Freitas RF, Abrahão O, Devienne KF, de Souza LR, Blaber SI, Blaber M, Kondo MY, Juliano MA, Juliano L, Puzer L. Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7. Bioorganic & Medicinal Chemistry Letters. 21: 6112-5. PMID 21903387 DOI: 10.1016/j.bmcl.2011.08.044  1
2011 Krenzer S, Peterziel H, Mauch C, Blaber SI, Blaber M, Angel P, Hess J. Expression and function of the kallikrein-related peptidase 6 in the human melanoma microenvironment. The Journal of Investigative Dermatology. 131: 2281-8. PMID 21753781 DOI: 10.1038/jid.2011.190  1
2011 Andrade D, Assis DM, Santos JA, Alves FM, Hirata IY, Araujo MS, Blaber SI, Blaber M, Juliano MA, Juliano L. Substrate specificity of kallikrein-related peptidase 13 activated by salts or glycosaminoglycans and a search for natural substrate candidates. Biochimie. 93: 1701-9. PMID 21689719 DOI: 10.1016/j.biochi.2011.05.037  1
2011 Scarisbrick IA, Epstein B, Cloud BA, Yoon H, Wu J, Renner DN, Blaber SI, Blaber M, Vandell AG, Bryson AL. Functional role of kallikrein 6 in regulating immune cell survival. Plos One. 6: e18376. PMID 21464892 DOI: 10.1371/journal.pone.0018376  1
2011 Lee J, Blaber SI, Dubey VK, Blaber M. A polypeptide "building block" for the β-trefoil fold identified by "top-down symmetric deconstruction". Journal of Molecular Biology. 407: 744-63. PMID 21315087 DOI: 10.1016/j.jmb.2011.02.002  1
2011 Lee J, Blaber M. Experimental support for the evolution of symmetric protein architecture from a simple peptide motif. Proceedings of the National Academy of Sciences of the United States of America. 108: 126-30. PMID 21173271 DOI: 10.1073/pnas.1015032108  1
2010 Andrade D, Assis DM, Lima AR, Oliveira JR, Araujo MS, Blaber SI, Blaber M, Juliano MA, Juliano L. Substrate specificity and inhibition of human kallikrein-related peptidase 3 (KLK3 or PSA) activated with sodium citrate and glycosaminoglycans. Archives of Biochemistry and Biophysics. 498: 74-82. PMID 20371359 DOI: 10.1016/j.abb.2010.03.022  1
2010 Blaber M, Yoon H, Juliano MA, Scarisbrick IA, Blaber SI. Functional intersection of the kallikrein-related peptidases (KLKs) and thrombostasis axis. Biological Chemistry. 391: 311-20. PMID 20128685 DOI: 10.1515/BC.2010.024  1
2009 Meher AK, Blaber SI, Lee J, Honjo E, Kuroki R, Blaber M. Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 1136-40. PMID 19923735 DOI: 10.1107/S1744309109036987  1
2009 Lee J, Blaber SI, Irsigler A, Aspinwall E, Blaber M. X-ray structure and biophysical properties of rabbit fibroblast growth factor 1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 1097-104. PMID 19923726 DOI: 10.1107/S1744309109040287  1
2009 Kogot JM, Parker AM, Lee J, Blaber M, Strouse GF, Logan TM. Analysis of the dynamics of assembly and structural impact for a histidine tagged FGF1-1.5 nm Au nanoparticle bioconjugate. Bioconjugate Chemistry. 20: 2106-13. PMID 19810698 DOI: 10.1021/bc900224d  1
2009 Lee J, Blaber M. The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1. Journal of Molecular Biology. 393: 113-27. PMID 19695265 DOI: 10.1016/j.jmb.2009.08.026  1
2009 Lee J, Blaber M. Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine. Journal of Molecular Biology. 393: 128-39. PMID 19683004 DOI: 10.1016/j.jmb.2009.08.007  1
2009 Yoon H, Blaber SI, Debela M, Goettig P, Scarisbrick IA, Blaber M. A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15. Biological Chemistry. 390: 373-7. PMID 19090718 DOI: 10.1515/BC.2009.026  1
2008 Lima AR, Alves FM, Angelo PF, Andrade D, Blaber SI, Blaber M, Juliano L, Juliano MA. S(1)' and S(2)' subsite specificities of human plasma kallikrein and tissue kallikrein 1 for the hydrolysis of peptides derived from the bradykinin domain of human kininogen. Biological Chemistry. 389: 1487-94. PMID 18844446 DOI: 10.1515/BC.2008.166  1
2008 Vandell AG, Larson N, Laxmikanthan G, Panos M, Blaber SI, Blaber M, Scarisbrick IA. Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines. Journal of Neurochemistry. 107: 855-70. PMID 18778305  1
2008 Yoon H, Blaber SI, Evans DM, Trim J, Juliano MA, Scarisbrick IA, Blaber M. Activation profiles of human kallikrein-related peptidases by proteases of the thrombostasis axis. Protein Science : a Publication of the Protein Society. 17: 1998-2007. PMID 18697857 DOI: 10.1110/ps.036715.108  1
2008 Scarisbrick IA, Linbo R, Vandell AG, Keegan M, Blaber SI, Blaber M, Sneve D, Lucchinetti CF, Rodriguez M, Diamandis EP. Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration. Biological Chemistry. 389: 739-45. PMID 18627300 DOI: 10.1515/BC.2008.085  1
2008 Honjo E, Tamada T, Adachi M, Kuroki R, Meher A, Blaber M. Mutagenesis of the crystal contact of acidic fibroblast growth factor. Journal of Synchrotron Radiation. 15: 285-7. PMID 18421160 DOI: 10.1107/S0909049508004470  1
2008 Li HX, Hwang BY, Laxmikanthan G, Blaber SI, Blaber M, Golubkov PA, Ren P, Iverson BL, Georgiou G. Substrate specificity of human kallikreins 1 and 6 determined by phage display. Protein Science : a Publication of the Protein Society. 17: 664-72. PMID 18359858 DOI: 10.1110/ps.073333208  1
2008 Lee J, Dubey VK, Longo LM, Blaber M. A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif. Journal of Molecular Biology. 377: 1251-64. PMID 18308335 DOI: 10.1016/j.jmb.2008.01.055  1
2007 Yoon H, Laxmikanthan G, Lee J, Blaber SI, Rodriguez A, Kogot JM, Scarisbrick IA, Blaber M. Activation profiles and regulatory cascades of the human kallikrein-related peptidases. The Journal of Biological Chemistry. 282: 31852-64. PMID 17823117 DOI: 10.1074/jbc.M705190200  1
2007 Dubey VK, Lee J, Somasundaram T, Blaber S, Blaber M. Spackling the crack: stabilizing human fibroblast growth factor-1 by targeting the N and C terminus beta-strand interactions. Journal of Molecular Biology. 371: 256-68. PMID 17570396 DOI: 10.1016/j.jmb.2007.05.065  1
2007 Blaber SI, Yoon H, Scarisbrick IA, Juliano MA, Blaber M. The autolytic regulation of human kallikrein-related peptidase 6. Biochemistry. 46: 5209-17. PMID 17417874 DOI: 10.1021/bi6025006  1
2006 Oikonomopoulou K, Hansen KK, Saifeddine M, Tea I, Blaber M, Blaber SI, Scarisbrick I, Andrade-Gordon P, Cottrell GS, Bunnett NW, Diamandis EP, Hollenberg MD. Proteinase-activated receptors, targets for kallikrein signaling. The Journal of Biological Chemistry. 281: 32095-112. PMID 16885167 DOI: 10.1074/jbc.M513138200  1
2006 Scarisbrick IA, Blaber SI, Tingling JT, Rodriguez M, Blaber M, Christophi GP. Potential scope of action of tissue kallikreins in CNS immune-mediated disease. Journal of Neuroimmunology. 178: 167-76. PMID 16824622 DOI: 10.1016/j.jneuroim.2006.05.022  1
2006 Oikonomopoulou K, Hansen KK, Saifeddine M, Vergnolle N, Tea I, Blaber M, Blaber SI, Scarisbrick I, Diamandis EP, Hollenberg MD. Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs). Biological Chemistry. 387: 817-24. PMID 16800746 DOI: 10.1515/BC.2006.104  1
2006 Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis EP, Fritz H, Lilja H, Malm J, Maltais LJ, Olsson AY, Petraki C, Scorilas A, Sotiropoulou G, Stenman UH, et al. A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biological Chemistry. 387: 637-41. PMID 16800724 DOI: 10.1515/BC.2006.082  1
2006 Lee J, Dubey VK, Somasundaram T, Blaber M. Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: effects upon structure, stability, folding, and mitogenic function. Proteins. 62: 686-97. PMID 16355415 DOI: 10.1002/prot.20808  1
2006 Angelo PF, Lima AR, Alves FM, Blaber SI, Scarisbrick IA, Blaber M, Juliano L, Juliano MA. Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects. The Journal of Biological Chemistry. 281: 3116-26. PMID 16321973 DOI: 10.1074/jbc.M510096200  1
2005 Dubey VK, Lee J, Blaber M. Redesigning symmetry-related "mini-core" regions of FGF-1 to increase primary structure symmetry: thermodynamic and functional consequences of structural symmetry. Protein Science : a Publication of the Protein Society. 14: 2315-23. PMID 16081654 DOI: 10.1110/ps.051494405  1
2005 Adamek DH, Guerrero L, Blaber M, Caspar DL. Structural and energetic consequences of mutations in a solvated hydrophobic cavity. Journal of Molecular Biology. 346: 307-18. PMID 15663946 DOI: 10.1016/j.jmb.2004.11.046  1
2005 Laxmikanthan G, Blaber SI, Bernett MJ, Scarisbrick IA, Juliano MA, Blaber M. 1.70 A X-ray structure of human apo kallikrein 1: structural changes upon peptide inhibitor/substrate binding. Proteins. 58: 802-14. PMID 15651049 DOI: 10.1002/prot.20368  1
2005 Kim J, Lee J, Brych SR, Logan TM, Blaber M. Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor. Protein Science : a Publication of the Protein Society. 14: 351-9. PMID 15632285 DOI: 10.1110/ps.041094205  1
2004 Christophi GP, Isackson PJ, Blaber S, Blaber M, Rodriguez M, Scarisbrick IA. Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease. Journal of Neurochemistry. 91: 1439-49. PMID 15584920 DOI: 10.1111/j.1471-4159.2004.02826.x  1
2004 Brych SR, Dubey VK, Bienkiewicz E, Lee J, Logan TM, Blaber M. Symmetric primary and tertiary structure mutations within a symmetric superfold: a solution, not a constraint, to achieve a foldable polypeptide. Journal of Molecular Biology. 344: 769-80. PMID 15533444 DOI: 10.1016/j.jmb.2004.09.060  1
2004 Bernett MJ, Somasundaram T, Blaber M. An atomic resolution structure for human fibroblast growth factor 1. Proteins. 57: 626-34. PMID 15382229 DOI: 10.1002/prot.20239  1
2004 Blaber SI, Ciric B, Christophi GP, Bernett MJ, Blaber M, Rodriguez M, Scarisbrick IA. Targeting kallikrein 6 proteolysis attenuates CNS inflammatory disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 920-2. PMID 15033932 DOI: 10.1096/fj.03-1212fje  1
2004 Sanli G, Banta S, Anderson S, Blaber M. Structural alteration of cofactor specificity in Corynebacterium 2,5-diketo-D-gluconic acid reductase. Protein Science : a Publication of the Protein Society. 13: 504-12. PMID 14718658 DOI: 10.1110/ps.03450704  1
2004 Blaber M. Nano-dynamics: engineering allostery via tandem duplication and turn energetics. Trends in Biotechnology. 22: 1-2. PMID 14690614 DOI: 10.1016/j.tibtech.2003.10.010  0.01
2003 Brych SR, Kim J, Logan TM, Blaber M. Accommodation of a highly symmetric core within a symmetric protein superfold. Protein Science : a Publication of the Protein Society. 12: 2704-18. PMID 14627732 DOI: 10.1110/ps.03374903  1
2003 Kim J, Brych SR, Lee J, Logan TM, Blaber M. Identification of a key structural element for protein folding within beta-hairpin turns. Journal of Molecular Biology. 328: 951-61. PMID 12729767  1
2003 Sanli G, Dudley JI, Blaber M. Structural biology of the aldo-keto reductase family of enzymes: catalysis and cofactor binding. Cell Biochemistry and Biophysics. 38: 79-101. PMID 12663943 DOI: 10.1385/CBB:38:1:79  1
2002 Scarisbrick IA, Blaber SI, Lucchinetti CF, Genain CP, Blaber M, Rodriguez M. Activity of a newly identified serine protease in CNS demyelination. Brain : a Journal of Neurology. 125: 1283-96. PMID 12023317  1
2002 Bernett MJ, Blaber SI, Scarisbrick IA, Dhanarajan P, Thompson SM, Blaber M. Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system. The Journal of Biological Chemistry. 277: 24562-70. PMID 11983703 DOI: 10.1074/jbc.M202392200  1
2002 Kim J, Blaber SI, Blaber M. Alternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factor. Protein Science : a Publication of the Protein Society. 11: 459-66. PMID 11847269  1
2002 Blaber SI, Scarisbrick IA, Bernett MJ, Dhanarajan P, Seavy MA, Jin Y, Schwartz MA, Rodriguez M, Blaber M. Enzymatic properties of rat myelencephalon-specific protease. Biochemistry. 41: 1165-73. PMID 11802715  1
2001 Brych SR, Blaber SI, Logan TM, Blaber M. Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Science : a Publication of the Protein Society. 10: 2587-99. PMID 11714927 DOI: 10.1110/ps.ps.34701  1
2001 Sanli G, Blaber M. Structural assembly of the active site in an aldo-keto reductase by NADPH cofactor. Journal of Molecular Biology. 309: 1209-18. PMID 11399090 DOI: 10.1006/jmbi.2001.4739  1
2001 Sanli G, Blaber SI, Blaber M. Reduction of wobble-position GC bases in Corynebacteria genes and enhancement of PCR and heterologous expression. Journal of Molecular Microbiology and Biotechnology. 3: 123-6. PMID 11200224  1
2001 Grek SB, Davis JK, Blaber M. An efficient, flexible-model program for the analysis of differential scanning calorimetry protein denaturation data Protein and Peptide Letters. 8: 429-436. DOI: 10.2174/0929866013409184  1
2000 Culajay JF, Blaber SI, Khurana A, Blaber M. Thermodynamic characterization of mutants of human fibroblast growth factor 1 with an increased physiological half-life. Biochemistry. 39: 7153-8. PMID 10852713 DOI: 10.1021/bi9927742  1
2000 Scarisbrick IA, Asakura K, Blaber S, Blaber M, Isackson PJ, Bieto T, Rodriguez M, Windebank AJ. Preferential expression of myelencephalon-specific protease by oligodendrocytes of the adult rat spinal cord white matter. Glia. 30: 219-30. PMID 10756072 DOI: 10.1002/(SICI)1098-1136(200005)30:3<219::AID-GLIA2>3.0.CO;2-2  1
2000 Khurana S, Sanli G, Powers DB, Anderson S, Blaber M. Molecular modeling of substrate binding in wild-type and mutant Corynebacteria 2,5-diketo-D-gluconate reductases. Proteins. 39: 68-75. PMID 10737928 DOI: 10.1002/(SICI)1097-0134(20000401)39:1<68::AID-PROT7>3.0.CO;2-Y  1
1999 Blaber SI, Culajay JF, Khurana A, Blaber M. Reversible thermal denaturation of human FGF-1 induced by low concentrations of guanidine hydrochloride. Biophysical Journal. 77: 470-7. PMID 10388772 DOI: 10.1016/S0006-3495(99)76904-3  1
1999 Yu B, Blaber M, Gronenborn AM, Clore GM, Caspar DL. Disordered water within a hydrophobic protein cavity visualized by x-ray crystallography. Proceedings of the National Academy of Sciences of the United States of America. 96: 103-8. PMID 9874779 DOI: 10.1073/pnas.96.1.103  1
1998 Khurana S, Powers DB, Anderson S, Blaber M. Crystal structure of 2,5-diketo-D-gluconic acid reductase A complexed with NADPH at 2.1-A resolution. Proceedings of the National Academy of Sciences of the United States of America. 95: 6768-73. PMID 9618487  1
1997 Blaber M, Adamek DH, Popovic A, Blaber SI. Biophysical and structural analysis of human acidic fibroblast growth factor Techniques in Protein Chemistry. 8: 745-753. DOI: 10.1016/S1080-8914(97)80073-7  1
1997 Blaber M. Crystallization and preliminary x-ray analysis of mouse pro-renin converting enzyme Protein and Peptide Letters. 4: 207-210.  1
1997 Khurana S, Powers DB, Anderson S, Blaber M. Preliminary x-ray crystallographic analysis and molecular replacement studies with 2,5-diketo-d-gluconate reductase Protein and Peptide Letters. 4: 287-290.  1
1996 Blaber M, DiSalvo J, Thomas KA. X-ray crystal structure of human acidic fibroblast growth factor Biochemistry. 35: 2086-2094. PMID 8652550 DOI: 10.1021/bi9521755  1
1995 Blaber M, Baase WA, Gassner N, Matthews BW. Alanine Scanning Mutagenesis of the α-Helix 115-123 of Phage T4 Lysozyme: Effects on Structure, Stability and the Binding of Solvent Journal of Molecular Biology. 246: 317-330. PMID 7869383 DOI: 10.1006/jmbi.1994.0087  1
1994 Blaber M, Zhang XJ, Lindstrom JD, Pepiot SD, Baase WA, Matthews BW. Determination of α-helix propensity within the context of a folded protein: Sites 44 and 131 in bacteriophage T4 lysozyme Journal of Molecular Biology. 235: 600-624. PMID 8289284  1
1994 Heinz DW, Baase WA, Zhang XJ, Blaber M, Dahlquist FW, Matthews BW. Accommodation of amino acid insertions in an alpha-helix of T4 lysozyme. Structural and thermodynamic analysis. Journal of Molecular Biology. 236: 869-86. PMID 8114100 DOI: 10.1006/jmbi.1994.1195  1
1993 Blaber M, Zhang XJ, Matthews BW. Structural basis of amino acid α helix propensity Science. 260: 1637-1640. PMID 8503008  1
1993 Bax B, Blaber M, Ferguson G, Sternberg MJE, Walls PH. Prediction of the three-dimensional structures of the nerve growth factor and epidermal growth factor binding proteins (kallikreins) and an hypothetical structure of the high molecular weight complex of epidermal growth factor with its binding protein Protein Science. 2: 1229-1241. PMID 8401208  1
1993 Blaber M, Isackson PJ, Holden HM, Bradshaw RA. Synthetic chimeras of mouse growth factor-associated glandular kallikreins. II. Growth factor binding properties. Protein Science : a Publication of the Protein Society. 2: 1220-8. PMID 8401207 DOI: 10.1002/pro.5560020804  1
1993 Blaber M, Isackson PJ, Burnier JP, Marsters JC, Bradshaw RA. Synthetic chimeras of mouse growth factor-associated glandular kallikreins. I. Kinetic properties. Protein Science : a Publication of the Protein Society. 2: 1210-9. PMID 8401206 DOI: 10.1002/pro.5560020803  1
1993 Shortle D, Clarke N, Blaber M, Zhang XJ, Matthews BW. Alpha helix propensity of amino acids Science. 262: 917-918. PMID 8235616  1
1993 Blaber M, Lindstrom JD, Gassner N, Xu J, Heinz DW, Matthews BW. Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala → Ser and Val → Thr substitutions in T4 lysozyme Biochemistry. 32: 11363-11373. PMID 8218201 DOI: 10.1021/bi00093a013  1
1992 Eriksson AE, Baase WA, Zhang XJ, Heinz DW, Blaber M, Baldwin EP, Matthews BW. Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effect. Science (New York, N.Y.). 255: 178-83. PMID 1553543  0.84
1992 Baase WA, Eriksson AE, Zhang XJ, Heinz DW, Sauer U, Blaber M, Baldwin EP, Wozniak JA, Matthews BW. Dissection of protein structure and folding by directed mutagenesis. Faraday Discussions. 173-81. PMID 1290931 DOI: 10.1039/FD9929300173  1
1990 Blaber M, Isackson PJ, Bradshaw RA. The characterization of recombinant mouse glandular kallikreins from E. coli Proteins: Structure, Function and Genetics. 7: 280-290. PMID 2194219 DOI: 10.1002/prot.340070309  1
1990 Sinha S, Dovey HF, Seubert P, Ward PJ, Blacher RW, Blaber M, Bradshaw RA, Arici M, Mobley WC, Lieberburg I. The protease inhibitory properties of the Alzheimer's beta-amyloid precursor protein. The Journal of Biological Chemistry. 265: 8983-5. PMID 2111813  1
1990 Bradshaw RA, Altin JG, Blaber M, Cavanaugh KP, Eveleth DD, Kornblum HI, Leslie FM, Raffioni S. Neurotrophic factors in the CNS: biosynthetic processing and functional responses. Progress in Brain Research. 86: 157-67. PMID 1965051  1
1989 Blaber M, Isackson PJ, Marsters JC, Burnier JP, Bradshaw RA. Substrate specificities of growth factor associated kallikreins of the mouse submandibular gland Biochemistry. 28: 7813-7819. PMID 2611215  1
1987 Blaber M, Isackson PJ, Bradshaw RA. A complete cDNA sequence for the major epidermal growth factor binding protein in the male mouse submandibular gland Biochemistry. 26: 6742-6749. PMID 3322386  1
1987 Isackson PJ, Silverman RE, Blaber M, Server AC, Nichols RA, Shooter EM, Bradshaw RA. Epidermal growth factor binding protein: identification of a different protein. Biochemistry. 26: 2082-5. PMID 3304419  1
1987 Mcalister-Henn L, Blaber M, Bradshaw RA, Nisco SJ. Complete nucleotide sequence of the Escherichia coli gene encoding malate dehydrogenase Nucleic Acids Research. 15: 4993. PMID 3299262 DOI: 10.1093/nar/15.12.4993  1
1986 Winkler ME, Blaber M. Purification and characterization of recombinant single-chain urokinase produced in Escherichia coli Biochemistry. 25: 4041-4045. PMID 3527262  1
1986 Lynen HR, Zamarron C, Blaber M. Activation of plasminogen by pro-urokinase. I. Mechanism Journal of Biological Chemistry. 261: 1253-1258. PMID 2935528  1
1985 Winkler ME, Blaber M, Bennett GL, Holmes W, Vehar GA. Purification and characterization of recombinant urokinase from escherichia COU Bio/Technology. 3: 990-1000. DOI: 10.1038/nbt1185-990  1
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