Sarah Hamm-Alvarez - Publications

Affiliations: 
University of Southern California, Los Angeles, CA, United States 
Area:
Cell Biology, Biochemistry

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lee C, Edman MC, Laurie GW, Hamm-Alvarez SF, MacKay JA. Biosynthesized Multivalent Lacritin Peptides Stimulate Exosome Production in Human Corneal Epithelium. International Journal of Molecular Sciences. 21. PMID 32859014 DOI: 10.3390/ijms21176157  0.56
2020 Kakan SS, Janga SR, Cooperman B, Craig DW, Edman MC, Okamoto CT, Hamm-Alvarez SF. Small RNA Deep Sequencing Identifies a Unique miRNA Signature Released in Serum Exosomes in a Mouse Model of Sjögren's Syndrome. Frontiers in Immunology. 11: 1475. PMID 32849505 DOI: 10.3389/fimmu.2020.01475  0.56
2020 Ju Y, Guo H, Edman M, Hamm-Alvarez SF. Application of advances in endocytosis and membrane trafficking to drug delivery. Advanced Drug Delivery Reviews. PMID 32758615 DOI: 10.1016/j.addr.2020.07.026  0.4
2020 Tyrpak DR, Wang Y, Avila H, Guo H, Fu R, Truong AT, Park M, Okamoto CT, Hamm-Alvarez SF, MacKay JA. Caveolin elastin-like polypeptide fusions mediate temperature-dependent assembly of caveolar microdomains. Acs Biomaterials Science & Engineering. 6: 198-204. PMID 32542186 DOI: 10.1021/acsbiomaterials.9b01331  0.56
2020 Hsueh PY, Ju Y, Vega A, Edman MC, MacKay JA, Hamm-Alvarez SF. A Multivalent ICAM-1 Binding Nanoparticle which Inhibits ICAM-1 and LFA-1 Interaction Represents a New Tool for the Investigation of Autoimmune-Mediated Dry Eye. International Journal of Molecular Sciences. 21. PMID 32326657 DOI: 10.3390/ijms21082758  0.56
2020 Edman MC, Janga SR, Kakan SS, Okamoto CT, Freire D, Feigenbaum D, Lew M, Hamm-Alvarez SF. Tears - more to them than meets the eye: why tears are a good source of biomarkers in Parkinson's disease. Biomarkers in Medicine. PMID 32064896 DOI: 10.2217/bmm-2019-0364  0.56
2020 Fu R, Guo H, Janga S, Choi M, Klinngam W, Edman MC, Hamm-Alvarez SF. Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjögren's syndrome murine model. Scientific Reports. 10: 1455. PMID 31996771 DOI: 10.1038/s41598-020-58337-4  0.52
2019 Hamm-Alvarez SF, Janga SR, Edman MC, Feigenbaum D, Freire D, Mack WJ, Okamoto CT, Lew MF. Levels of oligomeric α-Synuclein in reflex tears distinguish Parkinson's disease patients from healthy controls. Biomarkers in Medicine. PMID 31552762 DOI: 10.2217/bmm-2019-0315  0.56
2019 Ju Y, Guo H, Yarber F, Edman MC, Peddi S, Janga SR, MacKay JA, Hamm-Alvarez SF. Molecular Targeting of Immunosuppressants Using a Bi-functional Elastin-Like Polypeptide. Bioconjugate Chemistry. PMID 31408605 DOI: 10.1021/acs.bioconjchem.9b00462  0.56
2019 Fu R, Klinngam W, Heur M, Edman MC, Hamm-Alvarez SF. Tear Proteases and Protease Inhibitors: Potential Biomarkers and Disease Drivers in Ocular Surface Disease. Eye & Contact Lens. PMID 31369467 DOI: 10.1097/ICL.0000000000000641  0.52
2019 Klinngam W, Janga SR, Lee C, Ju Y, Yarber F, Shah M, Guo H, Wang D, MacKay JA, Edman MC, Hamm-Alvarez SF. Inhibition of Cathepsin S Reduces Lacrimal Gland Inflammation and Increases Tear Flow in a Mouse Model of Sjögren's Syndrome. Scientific Reports. 9: 9559. PMID 31267034 DOI: 10.1038/s41598-019-45966-7  0.56
2019 Hamm-Alvarez SF, Okamoto CT, Janga SR, Feigenbaum D, Edman MC, Freire D, Shah M, Ghanshani R, Mack WJ, Lew MF. Oligomeric α-synuclein is increased in basal tears of Parkinson's patients. Biomarkers in Medicine. PMID 31262201 DOI: 10.2217/bmm-2019-0167  0.56
2019 Lee C, Guo H, Klinngam W, Janga SR, Yarber F, Peddi S, Edman MC, Tiwari N, Liu S, Louie SG, Hamm-Alvarez SF, MacKay JA. Berunda polypeptides: Bi-headed rapamycin carriers for subcutaneous treatment of autoimmune dry eye disease. Molecular Pharmaceutics. PMID 31095909 DOI: 10.1021/acs.molpharmaceut.9b00263  0.56
2018 Klinngam W, Fu R, Janga SR, Edman MC, Hamm-Alvarez SF. Cathepsin S Alters the Expression of Pro-Inflammatory Cytokines and MMP-9, Partially through Protease-Activated Receptor-2, in Human Corneal Epithelial Cells. International Journal of Molecular Sciences. 19. PMID 30423938 DOI: 10.3390/ijms19113530  0.52
2018 Guo H, Lee C, Shah M, Janga SR, Edman MC, Klinngam W, Hamm-Alvarez SF, Andrew Mackay J. A novel elastin-like polypeptide drug carrier for cyclosporine A improves tear flow in a mouse model of Sjögren's syndrome. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30359668 DOI: 10.1016/j.jconrel.2018.10.026  0.52
2018 Ju Y, Janga SR, Klinngam W, MacKay JA, Hawley D, Zoukhri D, Edman MC, Hamm-Alvarez SF. NOD and NOR mice exhibit comparable development of lacrimal gland secretory dysfunction but NOD mice have more severe autoimmune dacryoadenitis. Experimental Eye Research. PMID 30201519 DOI: 10.1016/j.exer.2018.09.002  0.56
2018 Janga SR, Shah M, Ju Y, Meng Z, Edman M, Hamm-Alvarez SF. Longitudinal Analysis of Tear Cathepsin S Activity Levels in Male Non-Obese Diabetic Mice Suggests its Potential as an Early Stage Biomarker of Sjögren's Syndrome. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 1-35. PMID 30126300 DOI: 10.1080/1354750X.2018.1514656  0.4
2018 Edman MC, Janga SR, Meng Z, Bechtold M, Chen AF, Kim C, Naman L, Sarma A, Teekappanavar N, Kim AY, Madrigal S, Singh S, Ortiz E, Christianakis S, Arkfeld DG, ... ... Hamm-Alvarez SF, et al. Increased Cathepsin S activity associated with decreased protease inhibitory capacity contributes to altered tear proteins in Sjögren's Syndrome patients. Scientific Reports. 8: 11044. PMID 30038391 DOI: 10.1038/s41598-018-29411-9  0.52
2017 Meng Z, Klinngam W, Edman MC, Hamm-Alvarez SF. Interferon-γ treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of Sjögren's Syndrome. Plos One. 12: e0184781. PMID 28902875 DOI: 10.1371/journal.pone.0184781  0.52
2017 Aluri HS, Samizadeh M, Edman MC, Hawley DR, Armaos HL, Janga SR, Meng Z, Sendra VG, Hamrah P, Kublin CL, Hamm-Alvarez SF, Zoukhri D. Delivery of Bone Marrow-Derived Mesenchymal Stem Cells Improves Tear Production in a Mouse Model of Sjögren's Syndrome. Stem Cells International. 2017: 3134543. PMID 28348600 DOI: 10.1155/2017/3134543  0.52
2017 Shah M, Edman MC, Reddy Janga S, Yarber F, Meng Z, Klinngam W, Bushman J, Ma T, Liu S, Louie S, Mehta A, Ding C, MacKay JA, Hamm-Alvarez SF. Rapamycin Eye Drops Suppress Lacrimal Gland Inflammation In a Murine Model of Sjögren's Syndrome. Investigative Ophthalmology & Visual Science. 58: 372-385. PMID 28122086 DOI: 10.1167/iovs.16-19159  0.56
2016 Meng Z, Edman MC, Hsueh PY, Chen CY, Klinngam W, Tolmachova T, Okamoto CT, Hamm-Alvarez SF. Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome. American Journal of Physiology. Cell Physiology. ajpcell.00275.2015. PMID 27076615 DOI: 10.1152/ajpcell.00275.2015  0.84
2015 Despanie J, Dhandhukia JP, Hamm-Alvarez SF, MacKay JA. Elastin-like polypeptides: Therapeutic applications for an emerging class of nanomedicines. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26578439 DOI: 10.1016/j.jconrel.2015.11.010  0.52
2015 Hsueh PY, Edman MC, Sun G, Shi P, Xu S, Lin YA, Cui H, Hamm-Alvarez SF, MacKay JA. Tear-mediated delivery of nanoparticles through transcytosis of the lacrimal gland. Journal of Controlled Release : Official Journal of the Controlled Release Society. 208: 2-13. PMID 25523518 DOI: 10.1016/j.jconrel.2014.12.017  0.84
2015 Wang W, Jashnani A, Aluri SR, Gustafson JA, Hsueh PY, Yarber F, McKown RL, Laurie GW, Hamm-Alvarez SF, MacKay JA. A thermo-responsive protein treatment for dry eyes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 199: 156-67. PMID 25481446 DOI: 10.1016/j.jconrel.2014.11.016  0.84
2014 Wang W, Despanie J, Shi P, Edman-Woolcott MC, Lin YA, Cui H, Heur JM, Fini ME, Hamm-Alvarez SF, MacKay JA. Lacritin-mediated regeneration of the corneal epithelia by protein polymer nanoparticles. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 2: 8131-8141. PMID 25530855 DOI: 10.1039/C4TB00979G  0.84
2014 Pastuszka MK, Okamoto CT, Hamm-Alvarez SF, MacKay JA. Flipping the Switch on Clathrin-Mediated Endocytosis using Thermally Responsive Protein Microdomains. Advanced Functional Materials. 24: 5340-5347. PMID 25419208 DOI: 10.1002/adfm.201400715  0.84
2014 Hamm-Alvarez SF, Janga SR, Edman MC, Madrigal S, Shah M, Frousiakis SE, Renduchintala K, Zhu J, Bricel S, Silka K, Bach D, Heur M, Christianakis S, Arkfeld DG, Irvine J, et al. Tear cathepsin S as a candidate biomarker for Sjögren's syndrome. Arthritis & Rheumatology (Hoboken, N.J.). 66: 1872-81. PMID 24644101 DOI: 10.1002/art.38633  0.84
2013 Shah M, Edman MC, Janga SR, Shi P, Dhandhukia J, Liu S, Louie SG, Rodgers K, Mackay JA, Hamm-Alvarez SF. A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren's syndrome. Journal of Controlled Release : Official Journal of the Controlled Release Society. 171: 269-79. PMID 23892265 DOI: 10.1016/j.jconrel.2013.07.016  0.84
2013 Xu S, Ma L, Evans E, Okamoto CT, Hamm-Alvarez SF. Polymeric immunoglobulin receptor traffics through two distinct apically targeted pathways in primary lacrimal gland acinar cells. Journal of Cell Science. 126: 2704-17. PMID 23606742 DOI: 10.1242/jcs.122242  0.84
2013 Fazlollahi F, Kim YH, Sipos A, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED. Nanoparticle translocation across mouse alveolar epithelial cell monolayers: species-specific mechanisms. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 786-94. PMID 23454523 DOI: 10.1016/j.nano.2013.01.007  0.84
2013 Gonzalez JM, Hamm-Alvarez S, Tan JC. Analyzing live cellularity in the human trabecular meshwork. Investigative Ophthalmology & Visual Science. 54: 1039-47. PMID 23249706 DOI: 10.1167/iovs.12-10479  0.84
2013 Xu S, Olenyuk BZ, Okamoto CT, Hamm-Alvarez SF. Targeting receptor-mediated endocytotic pathways with nanoparticles: rationale and advances. Advanced Drug Delivery Reviews. 65: 121-38. PMID 23026636 DOI: 10.1016/j.addr.2012.09.041  0.84
2012 Pastuszka MK, Janib SM, Weitzhandler I, Okamoto CT, Hamm-Alvarez S, Mackay JA. A tunable and reversible platform for the intracellular formation of genetically engineered protein microdomains. Biomacromolecules. 13: 3439-44. PMID 23088632 DOI: 10.1021/bm301090x  0.84
2012 Tan JC, Gonzalez JM, Hamm-Alvarez S, Song J. In situ autofluorescence visualization of human trabecular meshwork structure. Investigative Ophthalmology & Visual Science. 53: 2080-8. PMID 22410566 DOI: 10.1167/iovs.11-8141  0.84
2012 Chiang L, Karvar S, Hamm-Alvarez SF. Direct imaging of RAB27B-enriched secretory vesicle biogenesis in lacrimal acinar cells reveals origins on a nascent vesicle budding site. Plos One. 7: e31789. PMID 22363735 DOI: 10.1371/journal.pone.0031789  0.84
2012 Lagor WR, Fields DW, Khetarpal SA, Kumaravel A, Lin W, Weintraub N, Wu K, Hamm-Alvarez SF, Drazul-Schrader D, de la Llera-Moya M, Rothblat GH, Rader DJ. The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice. Plos One. 7: e31616. PMID 22363685 DOI: 10.1371/journal.pone.0031616  0.84
2012 Contreras J, Hsueh PY, Pei H, Hamm-Alvarez SF. Use of nucleofection to efficiently transfect primary rabbit lacrimal gland acinar cells. Cytotechnology. 64: 149-56. PMID 22138892 DOI: 10.1007/s10616-011-9404-3  0.84
2011 Fazlollahi F, Sipos A, Kim YH, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED. Translocation of PEGylated quantum dots across rat alveolar epithelial cell monolayers. International Journal of Nanomedicine. 6: 2849-57. PMID 22131830 DOI: 10.2147/IJN.S26051  0.84
2011 Xu S, Edman M, Kothawala MS, Sun G, Chiang L, Mircheff A, Zhu L, Okamoto C, Hamm-Alvarez S. A Rab11a-enriched subapical membrane compartment regulates a cytoskeleton-dependent transcytotic pathway in secretory epithelial cells of the lacrimal gland. Journal of Cell Science. 124: 3503-14. PMID 21984810 DOI: 10.1242/jcs.088906  0.84
2011 Contreras J, Elnagar AY, Hamm-Alvarez SF, Camarero JA. Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways. Journal of Controlled Release : Official Journal of the Controlled Release Society. 155: 134-43. PMID 21906641 DOI: 10.1016/j.jconrel.2011.08.030  0.84
2011 Sun G, Hsueh PY, Janib SM, Hamm-Alvarez S, MacKay JA. Design and cellular internalization of genetically engineered polypeptide nanoparticles displaying adenovirus knob domain. Journal of Controlled Release : Official Journal of the Controlled Release Society. 155: 218-26. PMID 21699930 DOI: 10.1016/j.jconrel.2011.06.010  0.84
2011 Chiang L, Ngo J, Schechter JE, Karvar S, Tolmachova T, Seabra MC, Hume AN, Hamm-Alvarez SF. Rab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland. American Journal of Physiology. Cell Physiology. 301: C507-21. PMID 21525430 DOI: 10.1152/ajpcell.00355.2010  0.84
2011 Fazlollahi F, Angelow S, Yacobi NR, Marchelletta R, Yu AS, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED. Polystyrene nanoparticle trafficking across MDCK-II. Nanomedicine : Nanotechnology, Biology, and Medicine. 7: 588-94. PMID 21310266 DOI: 10.1016/j.nano.2011.01.008  0.84
2010 Kim YH, Fazlollahi F, Kennedy IM, Yacobi NR, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED. Alveolar epithelial cell injury due to zinc oxide nanoparticle exposure. American Journal of Respiratory and Critical Care Medicine. 182: 1398-409. PMID 20639441 DOI: 10.1164/rccm.201002-0185OC  0.84
2010 Li X, Wu K, Edman M, Schenke-Layland K, MacVeigh-Aloni M, Janga SR, Schulz B, Hamm-Alvarez SF. Increased expression of cathepsins and obesity-induced proinflammatory cytokines in lacrimal glands of male NOD mouse. Investigative Ophthalmology & Visual Science. 51: 5019-29. PMID 20463324 DOI: 10.1167/iovs.09-4523  0.84
2010 Contreras J, Xie J, Chen YJ, Pei H, Zhang G, Fraser CL, Hamm-Alvarez SF. Intracellular uptake and trafficking of difluoroboron dibenzoylmethane-polylactide nanoparticles in HeLa cells. Acs Nano. 4: 2735-47. PMID 20420413 DOI: 10.1021/nn901385y  0.84
2010 Schenke-Layland K, Xie J, Magnusson M, Angelis E, Li X, Wu K, Reinhardt DP, Maclellan WR, Hamm-Alvarez SF. Lymphocytic infiltration leads to degradation of lacrimal gland extracellular matrix structures in NOD mice exhibiting a Sjögren's syndrome-like exocrinopathy. Experimental Eye Research. 90: 223-37. PMID 19852957 DOI: 10.1016/j.exer.2009.10.008  0.84
2010 Yacobi NR, Malmstadt N, Fazlollahi F, DeMaio L, Marchelletta R, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED. Mechanisms of alveolar epithelial translocation of a defined population of nanoparticles. American Journal of Respiratory Cell and Molecular Biology. 42: 604-14. PMID 19574531 DOI: 10.1165/rcmb.2009-0138OC  0.84
2009 Hamm-Alvarez S, Cadenas E. Mitochondrial medicine and therapeutics, Part II. Preface. Advanced Drug Delivery Reviews. 61: 1233. PMID 19835920 DOI: 10.1016/j.addr.2009.10.002  0.84
2009 Wu K, Joffre C, Li X, MacVeigh-Aloni M, Hom M, Hwang J, Ding C, Gregoire S, Bretillon L, Zhong JF, Hamm-Alvarez SF. Altered expression of genes functioning in lipid homeostasis is associated with lipid deposition in NOD mouse lacrimal gland. Experimental Eye Research. 89: 319-32. PMID 19345210 DOI: 10.1016/j.exer.2009.03.020  0.84
2009 Xie J, Marchelletta RR, Thomas PB, Jacobs DT, Yarber FA, Cheney RE, Hamm-Alvarez SF, Trousdale MD. Transduced viral IL-10 is exocytosed from lacrimal acinar secretory vesicles in a myosin-dependent manner in response to carbachol. Experimental Eye Research. 88: 467-78. PMID 19056381 DOI: 10.1016/j.exer.2008.10.023  0.84
2009 Marchelletta RR, Hamm-Alvarez SF. Microtubules, Actin Filaments and Motor-Mediated Vesicular Transport The Liver: Biology and Pathobiology: Fifth Edition. 27-43. DOI: 10.1002/9780470747919.ch3  0.84
2008 Joo KI, Lei Y, Lee CL, Lo J, Xie J, Hamm-Alvarez SF, Wang P. Site-specific labeling of enveloped viruses with quantum dots for single virus tracking. Acs Nano. 2: 1553-62. PMID 19079775 DOI: 10.1021/nn8002136  0.84
2008 Hamm-Alvarez S, Cadenas E. Mitochondrial medicine and mitochondrion-based therapeutics. Advanced Drug Delivery Reviews. 60: 1437-8. PMID 18692102 DOI: 10.1016/j.addr.2008.07.001  0.84
2008 Marchelletta RR, Jacobs DT, Schechter JE, Cheney RE, Hamm-Alvarez SF. The class V myosin motor, myosin 5c, localizes to mature secretory vesicles and facilitates exocytosis in lacrimal acini. American Journal of Physiology. Cell Physiology. 295: C13-28. PMID 18434623 DOI: 10.1152/ajpcell.00330.2007  0.84
2008 Brockbank KG, MacLellan WR, Xie J, Hamm-Alvarez SF, Chen ZZ, Schenke-Layland K. Quantitative second harmonic generation imaging of cartilage damage. Cell and Tissue Banking. 9: 299-307. PMID 18431689 DOI: 10.1007/s10561-008-9070-7  0.84
2008 Yacobi NR, Demaio L, Xie J, Hamm-Alvarez SF, Borok Z, Kim KJ, Crandall ED. Polystyrene nanoparticle trafficking across alveolar epithelium. Nanomedicine : Nanotechnology, Biology, and Medicine. 4: 139-45. PMID 18375191 DOI: 10.1016/j.nano.2008.02.002  0.84
2008 Evans E, Zhang W, Jerdeva G, Chen CY, Chen X, Hamm-Alvarez SF, Okamoto CT. Direct interaction between Rab3D and the polymeric immunoglobulin receptor and trafficking through regulated secretory vesicles in lacrimal gland acinar cells. American Journal of Physiology. Cell Physiology. 294: C662-74. PMID 18171724 DOI: 10.1152/ajpcell.00623.2006  0.84
2008 Norouziyan F, Shen WC, Hamm-Alvarez SF. Tyrphostin A8 stimulates a novel trafficking pathway of apically endocytosed transferrin through Rab11-enriched compartments in Caco-2 cells. American Journal of Physiology. Cell Physiology. 294: C7-21. PMID 17959726 DOI: 10.1152/ajpcell.00372.2006  0.84
2008 Schenke-Layland K, Xie J, Angelis E, Starcher B, Wu K, Riemann I, MacLellan WR, Hamm-Alvarez SF. Increased degradation of extracellular matrix structures of lacrimal glands implicated in the pathogenesis of Sjögren's syndrome. Matrix Biology : Journal of the International Society For Matrix Biology. 27: 53-66. PMID 17689946 DOI: 10.1016/j.matbio.2007.07.005  0.84
2007 Wang Y, Chiu CT, Nakamura T, Walker AM, Petridou B, Trousdale MD, Hamm-Alvarez SF, Mircheff AK, Schechter JE. Traffic of endogenous, transduced, and endocytosed prolactin in rabbit lacrimal acinar cells. Experimental Eye Research. 85: 749-61. PMID 17904551 DOI: 10.1016/j.exer.2007.08.009  0.84
2007 Schenke-Layland K, Xie J, Heydarkhan-Hagvall S, Hamm-Alvarez SF, Stock UA, Brockbank KG, MacLellan WR. Optimized preservation of extracellular matrix in cardiac tissues: implications for long-term graft durability. The Annals of Thoracic Surgery. 83: 1641-50. PMID 17462373 DOI: 10.1016/j.athoracsur.2006.12.005  0.84
2007 Wang Y, Chiu CT, Nakamura T, Walker AM, Petridou B, Trousdale MD, Hamm-Alvarez SF, Schechter JE, Mircheff AK. Elevated prolactin redirects secretory vesicle traffic in rabbit lacrimal acinar cells. American Journal of Physiology. Endocrinology and Metabolism. 292: E1122-34. PMID 17164431 DOI: 10.1152/ajpendo.00381.2006  0.84
2006 Selvam S, Thomas PB, Hamm-Alvarez SF, Schechter JE, Stevenson D, Mircheff AK, Trousdale MD. Current status of gene delivery and gene therapy in lacrimal gland using viral vectors. Advanced Drug Delivery Reviews. 58: 1243-57. PMID 17056149 DOI: 10.1016/j.addr.2006.07.021  0.84
2006 Xie J, Chiang L, Contreras J, Wu K, Garner JA, Medina-Kauwe L, Hamm-Alvarez SF. Novel fiber-dependent entry mechanism for adenovirus serotype 5 in lacrimal acini. Journal of Virology. 80: 11833-51. PMID 16987972 DOI: 10.1128/JVI.00857-06  0.84
2006 Andersson SV, Hamm-Alvarez SF, Gierow JP. Integrin adhesion in regulation of lacrimal gland acinar cell secretion. Experimental Eye Research. 83: 543-53. PMID 16631165 DOI: 10.1016/j.exer.2006.02.006  0.84
2006 Wu K, Jerdeva GV, da Costa SR, Sou E, Schechter JE, Hamm-Alvarez SF. Molecular mechanisms of lacrimal acinar secretory vesicle exocytosis. Experimental Eye Research. 83: 84-96. PMID 16530759 DOI: 10.1016/j.exer.2005.11.009  0.84
2006 Rentsendorj A, Xie J, MacVeigh M, Agadjanian H, Bass S, Kim DH, Rossi J, Hamm-Alvarez SF, Medina-Kauwe LK. Typical and atypical trafficking pathways of Ad5 penton base recombinant protein: Implications for gene transfer Gene Therapy. 13: 821-836. PMID 16482205 DOI: 10.1038/sj.gt.3302729  0.84
2006 Ding C, MacVeigh M, Pidgeon M, da Costa SR, Wu K, Hamm-Alvarez SF, Schechter JE. Unique ultrastructure of exorbital lacrimal glands in male NOD and BALB/c mice. Current Eye Research. 31: 13-22. PMID 16421015 DOI: 10.1080/02713680500428613  0.84
2006 da Costa SR, Wu K, Veigh MM, Pidgeon M, Ding C, Schechter JE, Hamm-Alvarez SF. Male NOD mouse external lacrimal glands exhibit profound changes in the exocytotic pathway early in postnatal development. Experimental Eye Research. 82: 33-45. PMID 16005870 DOI: 10.1016/j.exer.2005.04.019  0.84
2005 Mircheff AK, Wang Y, Jean Mde S, Ding C, Trousdale MD, Hamm-Alvarez SF, Schechter JE. Mucosal immunity and self-tolerance in the ocular surface system. The Ocular Surface. 3: 182-92. PMID 17131026  0.84
2005 Jerdeva GV, Wu K, Yarber FA, Rhodes CJ, Kalman D, Schechter JE, Hamm-Alvarez SF. Actin and non-muscle myosin II facilitate apical exocytosis of tear proteins in rabbit lacrimal acinar epithelial cells. Journal of Cell Science. 118: 4797-812. PMID 16219687 DOI: 10.1242/jcs.02573  0.84
2005 Medina-Kauwe LK, Xie J, Hamm-Alvarez S. Intracellular trafficking of nonviral vectors Gene Therapy. 12: 1734-1751. PMID 16079885 DOI: 10.1038/sj.gt.3302592  0.84
2005 Jerdeva GV, Yarber FA, Trousdale MD, Rhodes CJ, Okamoto CT, Dartt DA, Hamm-Alvarez SF. Dominant-negative PKC-epsilon impairs apical actin remodeling in parallel with inhibition of carbachol-stimulated secretion in rabbit lacrimal acini. American Journal of Physiology. Cell Physiology. 289: C1052-68. PMID 15930141 DOI: 10.1152/ajpcell.00546.2004  0.84
2005 Rose CM, Qian L, Hakim L, Wang Y, Jerdeva GY, Marchelletta R, Nakamura T, Hamm-Alvarez SF, Mircheff AK. Accumulation of catalytically active proteases in lacrimal gland acinar cell endosomes during chronic ex vivo muscarinic receptor stimulation. Scandinavian Journal of Immunology. 61: 36-50. PMID 15644121 DOI: 10.1111/j.0300-9475.2005.01527.x  0.84
2005 Rentsendorj A, Agadjanian H, Chen X, Cirivello M, Macveigh M, Kedes L, Hamm-Alvarez S, Medina-Kauwe LK. The Ad5 fiber mediates nonviral gene transfer in the absence of the whole virus, utilizing a novel cell entry pathway Gene Therapy. 12: 225-237. PMID 15483666 DOI: 10.1038/sj.gt.3302402  0.84
2004 Chu C, Okamoto CT, Hamm-Alvarez SF, Lee VH. Stable transfection of MDCK cells with epitope-tagged human PepT1. Pharmaceutical Research. 21: 1970-3. PMID 15587917 DOI: 10.1023/B:PHAM.0000048186.86886.e6  0.84
2004 Qian L, Xie J, Rose CM, Sou E, Zeng H, Hamm-Alvarez SF, Mircheff AK. Altered traffic to the lysosome in an ex vivo lacrimal acinar cell model for chronic muscarinic receptor stimulation. Experimental Eye Research. 79: 665-75. PMID 15500825 DOI: 10.1016/j.exer.2004.07.007  0.84
2004 Xie J, Qian L, Wang Y, Hamm-Alvarez SF, Mircheff AK. Role of the microtubule cytoskeleton in traffic of EGF through the lacrimal acinar cell endomembrane network. Experimental Eye Research. 78: 1093-106. PMID 15109916 DOI: 10.1016/j.exer.2004.01.009  0.84
2004 Wang Y, Xie J, Yarber FA, Mazurek C, Trousdale MD, Kauwe-Medina LK, Kasahara N, Hamm-Alvarez SF. Adenoviral capsid modulates secretory compartment organization and function in acinar epithelial cells from rabbit lacrimal gland Gene Therapy. 11: 970-981. PMID 15029229 DOI: 10.1038/sj.gt.3302247  0.84
2004 Xie J, Qian L, Wang Y, Rose CM, Yang T, Nakamura T, Hamm-Alvarez SF, Mircheff AK. Novel biphasic traffic of endocytosed EGF to recycling and degradative compartments in lacrimal gland acinar cells. Journal of Cellular Physiology. 199: 108-25. PMID 14978740 DOI: 10.1002/jcp.10458  0.84
2003 Hamm-Alvarez SF, Xie J, Wang Y, Medina-Kauwe LK. Modulation of secretory functions in epithelia by adenovirus capsid proteins. Journal of Controlled Release : Official Journal of the Controlled Release Society. 93: 129-40. PMID 14636719 DOI: 10.1016/j.jconrel.2003.08.020  0.84
2003 Qian L, Wang Y, Xie J, Rose CM, Yang T, Nakamura T, Sandberg M, Zeng H, Schechter JE, Chow RH, Hamm-Alvarez SF, Mircheff AK. Biochemical changes contributing to functional quiescence in lacrimal gland acinar cells after chronic ex vivo exposure to a muscarinic agonist. Scandinavian Journal of Immunology. 58: 550-65. PMID 14629627 DOI: 10.1046/j.1365-3083.2003.01343.x  0.84
2003 da Costa SR, Okamoto CT, Hamm-Alvarez SF. Actin microfilaments et al.--the many components, effectors and regulators of epithelial cell endocytosis. Advanced Drug Delivery Reviews. 55: 1359-83. PMID 14597136 DOI: 10.1016/j.addr.2003.07.011  0.84
2003 Da Costa SR, Sou E, Xie J, Yarber FA, Okamoto CT, Pidgeon M, Kessels MM, Mircheff AK, Schechter JE, Qualmann B, Hamm-Alvarez SF. Impairing actin filament or syndapin functions promotes accumulation of clathrin-coated vesicles at the apical plasma membrane of acinar epithelial cells. Molecular Biology of the Cell. 14: 4397-413. PMID 12937279 DOI: 10.1091/mbc.E03-05-0315  0.84
2003 Wang Y, Jerdeva G, Yarber FA, da Costa SR, Xie J, Qian L, Rose CM, Mazurek C, Kasahara N, Mircheff AK, Hamm-Alvarez SF. Cytoplasmic dynein participates in apically targeted stimulated secretory traffic in primary rabbit lacrimal acinar epithelial cells. Journal of Cell Science. 116: 2051-65. PMID 12679381 DOI: 10.1242/jcs.00398  0.84
2003 Hamm-Alvarez SF, Okamoto CT. Endocytosis and sorting of macromolecules Advanced Drug Delivery Reviews. 55: 1351-1352. DOI: 10.1016/j.addr.2003.07.001  0.84
2002 Xie J, Qian L, Hamm-Alvarez SF, Mircheff AK. Epidermal growth factor traffic in lacrimal acinar cells. Advances in Experimental Medicine and Biology. 506: 213-7. PMID 12613910  0.84
2002 da Costa SR, Andersson S, Arber F, Okamoto C, Hamm-Alvarez S. Cytoskeletal participation in stimulated secretion and compensatory apical plasma membrane retrieval in lacrimal gland acinar cells. Advances in Experimental Medicine and Biology. 506: 199-205. PMID 12613908  0.84
2002 Mircheff AK, Qian L, Xie J, Wang Y, Hamm-Alvarez SF. M3 receptor autoimmunity: losing tolerance to a familiar protein. Advances in Experimental Medicine and Biology. 506: 51-8. PMID 12613888  0.84
2002 Mircheff AK, Xie J, Qian L, Hamm-Alvarez SF. Diverse perturbations may alter the lacrimal acinar cell autoantigenic spectra. Dna and Cell Biology. 21: 435-42. PMID 12167246 DOI: 10.1089/10445490260099728  0.84
2002 Yang L, Leong PK, Chen JO, Patel N, Hamm-Alvarez SF, McDonough AA. Acute hypertension provokes internalization of proximal tubule NHE3 without inhibition of transport activity. American Journal of Physiology. Renal Physiology. 282: F730-40. PMID 11880335 DOI: 10.1152/ajprenal.00298.2001  0.84
2002 Qian L, Yang T, Chen H, Xie J, Zeng H, Warren DW, MacVeigh M, Meneray MA, Hamm-Alvarez SF, Mircheff AK. Heterotrimeric GTP-binding proteins in the lacrimal acinar cell endomembrane system. Experimental Eye Research. 74: 7-22. PMID 11878814 DOI: 10.1006/exer.2001.1108  0.84
2002 Hamm-Alvarez SF. Focus on "EGF receptor downregulation depends on a trafficking motif in the distal tyrosine kinase domain". American Journal of Physiology. Cell Physiology. 282: C417-9. PMID 11832326 DOI: 10.1152/ajpcell.00550.2001  0.84
2001 Lindberg J, Fernandez MAM, Ropp JD, Hamm-Alvarez SF. Nocodazole treatment of CV-1 cells enhances nuclear/perinuclear accumulation of lipid-DNA complexes and increases gene expression Pharmaceutical Research. 18: 246-249. PMID 11405299 DOI: 10.1023/A:1011001022570  0.84
2001 Hamm-Alvarez SF, Chang A, Wang Y, Jerdeva G, Lin HH, Kim KJ, Ann DK. Etk/Bmx activation modulates barrier function in epithelial cells American Journal of Physiology - Cell Physiology. 280. PMID 11350762  0.84
2000 da Costa SR, Wang Y, Vilalta PM, Schönthal AH, Hamm-Alvarez SF. Changes in cytoskeletal organization in polyoma middle T antigen-transformed fibroblasts: involvement of protein phosphatase 2A and src tyrosine kinases. Cell Motility and the Cytoskeleton. 47: 253-68. PMID 11093247 DOI: 10.1002/1097-0169(200012)47:4<253::AID-CM1>3.0.CO;2-S  0.84
2000 Wang Y, Duncan R, Ann DK, Hamm-Alvarez SF. Identification of a novel taxol-sensitive kinase activity associated with the cytoskeleton Biochemical and Biophysical Research Communications. 277: 525-530. PMID 11061987 DOI: 10.1006/bbrc.2000.3707  0.84
2000 Zhang L, da Costa SR, Yarber FA, Runnegar M, Hamm-Alvarez SF. Protein phosphatase inhibitors alter cellular microtubules and reduce carbachol-dependent protein secretion in lacrimal acini. Current Eye Research. 20: 373-83. PMID 10855032  0.84
1999 Lee VH, Chu C, Mahlin ED, Basu SK, Ann DK, Bolger MB, Haworth IS, Yeung AK, Wu SK, Hamm-Alvarez S, Okamoto CT. Biopharmaceutics of transmucosal peptide and protein drug administration: role of transport mechanisms with a focus on the involvement of PepT1. Journal of Controlled Release : Official Journal of the Controlled Release Society. 62: 129-40. PMID 10518644 DOI: 10.1016/S0168-3659(99)00030-9  0.84
1999 Runnegar MT, Wei X, Hamm-Alvarez SF. Increased protein phosphorylation of cytoplasmic dynein results in impaired motor function Biochemical Journal. 342: 1-6. PMID 10432292 DOI: 10.1042/0264-6021:3420001  0.84
1999 Hamm-Alvarez SF. Targeting endocytosis and motor proteins to enhance DNA persistence Pharmaceutical Science and Technology Today. 2: 190-196. DOI: 10.1016/S1461-5347(99)00143-1  0.84
1998 Mircheff AK, Gierow JP, Yang T, Zhang J, Wood RL, Azzarolo AM, Warren DW, Zeng H, Guo Z, Kaslow HR, Hamm-Alvarez SF, Okamoto CT, Bachmann M. Sjogren's autoimmunity: How perturbation of recognition in endomembrane traffic may provoke pathological recognition at the cell surface Journal of Molecular Recognition. 11: 40-48. PMID 10076804 DOI: 10.1002/(SICI)1099-1352(199812)11:1/6<40::AID-JMR387>3.0.CO;2-X  0.84
1998 Sonee M, Barrón E, Yarber FA, Hamm-Alvarez SF. Taxol inhibits endosomal-lysosomal membrane trafficking at two distinct steps in CV-1 cells American Journal of Physiology - Cell Physiology. 275. PMID 9843725  0.84
1998 Bolger MB, Haworth IS, Yeung AK, Ann D, von Grafenstein H, Hamm-Alvarez S, Okamoto CT, Kim KJ, Basu SK, Wu S, Lee VH. Structure, function, and molecular modeling approaches to the study of the intestinal dipeptide transporter PepT1. Journal of Pharmaceutical Sciences. 87: 1286-91. PMID 9811478 DOI: 10.1021/js980090u  0.56
1998 Hamm-Alvarez SF, Sheetz MP. Microtubule-dependent vesicle transport: modulation of channel and transporter activity in liver and kidney. Physiological Reviews. 78: 1109-29. PMID 9790571  0.84
1998 Yeung AK, Basu SK, Wu SK, Chu C, Okamoto CT, Hamm-Alvarez SF, von Grafenstein H, Shen WC, Kim KJ, Bolger MB, Haworth IS, Ann DK, Lee VH. Molecular identification of a role for tyrosine 167 in the function of the human intestinal proton- coupled dipeptide transporter (hPepT1). Biochemical and Biophysical Research Communications. 250: 103-7. PMID 9735340 DOI: 10.1006/bbrc.1998.9283  0.84
1998 Hamm-Alvarez SF, da Costa SR, Sonee M, Warren DW, Mircheff AK. Kinesin activation drives the retrieval of secretory membranes following secretion in rabbit lacrimal acinar cells. Advances in Experimental Medicine and Biology. 438: 177-80. PMID 9634883  0.84
1998 Vilalta PM, Zhang L, Hamm-Alvarez SF. A novel taxol-induced vimentin phosphorylation and stabilization revealed by studies on stable microtubules and vimentin intermediate filaments Journal of Cell Science. 111: 1841-1852. PMID 9625747  0.84
1998 da Costa SR, Yarber FA, Zhang L, Sonee M, Hamm-Alvarez SF. Microtubules facilitate the stimulated secretion of beta-hexosaminidase in lacrimal acinar cells. Journal of Cell Science. 111: 1267-76. PMID 9547304  0.84
1998 Hamm-Alvarez SF. Molecular motors and their role in membrane traffic Advanced Drug Delivery Reviews. 29: 229-242. DOI: 10.1016/S0169-409X(97)00081-1  0.84
1998 Hamm-Alvarez SF, Runnegar M. Molecular motors and regulation of endocytosis Proceedings of the Controlled Release Society. 89-90.  0.84
1997 Runnegar M, Wei X, Berndt N, Hamm-Alvarez SF. Transferrin receptor recycling in rat hepatocytes is regulated by protein phosphatase 2A, possibly through effects on microtubule-dependent transport Hepatology. 26: 176-185. PMID 9214467  0.84
1997 Hamm-Alvarez SF, Da Costa S, Yang T, Wei X, Gierow JP, Mircheff AK. Cholinergic stimulation of lacrimal acinar cells promotes redistribution of membrane-associated kinesin and the secretory protein, β-hexosaminidase, and increases kinesin motor activity Experimental Eye Research. 64: 141-156. PMID 9176047 DOI: 10.1006/exer.1996.0198  0.84
1997 Sussman MA, Hamm-Alvarez SF, Vilalta PM, Welch S, Kedes L. Involvement of phosphorylation in doxorubicin-mediated myofibril degeneration: An immunofluorescence microscopy analysis Circulation Research. 80: 52-61. PMID 8978322  0.84
1997 Hamm-Alvarez SF, Da Costa SR, Yarber F. Changes in microtubule assembly do not alter the cytofratin network in lacrimal acini Investigative Ophthalmology and Visual Science. 38.  0.84
1996 Hamm-Alvarez SF, Sonee M, Loran-Goss K, Shen WC. Paclitaxel and nocodazole differentially alter endocytosis in cultured cells Pharmaceutical Research. 13: 1647-1656. PMID 8956329 DOI: 10.1023/A:1016432505275  0.84
1996 Hamm-Alvarez SF, Wei X, Berndt N, Runnegar M. Protein phosphatases independently regulate vesicle movement and microtubule subpopulations in hepatocytes American Journal of Physiology - Cell Physiology. 271. PMID 8843724  0.84
1996 Hamm-Alvarez SF. Microtubule-based motor proteins: New targets for enhancing drug delivery? Pharmaceutical Research. 13: 489-496. PMID 8710737 DOI: 10.1023/A:1016025500402  0.84
1996 Da Costa SR, Yang T, Mircheff AK, Hamm-Alvarez SF. Microtubule organization in reconstituted lacrimal gland acini Investigative Ophthalmology and Visual Science. 37.  0.84
1996 Hamm-Alvarez SF, Da Costa SR, Yang T, Wei XH, Mircheff AK. Kinesin activation accompanies stimulation of secretion in lacrimal acinar cells Investigative Ophthalmology and Visual Science. 37.  0.84
1996 Mircheff AK, Yang T, Zhang J, Hamm-Alvarez SF, Wood RL. Acinar cell endomembrane traffic may support processing and presentation of autoantigens Faseb Journal. 10.  0.84
1996 Hamilton-Wessler M, Ader M, Getty L, Dea MK, Hamm-Alvarez SF, Bergman RN. Taxol alters insulin's ability to stimulate glucose clearance Journal of Investigative Medicine. 44: 130A.  0.84
1994 McIlvain JM, Burkhardt JK, Hamm-Alvarez S, Argon Y, Sheetz MP. Regulation of kinesin activity by phosphorylation of kinesin-associated proteins. The Journal of Biological Chemistry. 269: 19176-82. PMID 8034676  0.84
1994 Hamm-Alvarez SF, Alayof BE, Himmel HM, Kim PY, Crews AL, Strauss HC, Sheetz MP. Coordinate depression of bradykinin receptor recycling and microtubule-dependent transport by taxol. Proceedings of the National Academy of Sciences of the United States of America. 91: 7812-6. PMID 7914372  0.84
1993 Hamm-Alvarez SF, Kim PY, Sheetz MP. Regulation of vesicle transport in CV-1 cells and extracts. Journal of Cell Science. 106: 955-66. PMID 7905879  0.84
1990 Hamm-Alvarez S, Sancar A, Rajagopalan KV. The folate cofactor of Escherichia coli DNA photolyase acts catalytically. The Journal of Biological Chemistry. 265: 18656-62. PMID 2211728  0.84
1990 Hamm-Alvarez SF, Sancar A, Rajagopalan KV. The presence and distribution of reduced folates in Escherichia coli dihydrofolate reductase mutants. The Journal of Biological Chemistry. 265: 9850-6. PMID 2190985  0.84
1989 Hamm-Alvarez S, Sancar A, Rajagopalan KV. Role of enzyme-bound 5,10-methenyltetrahydropteroylpolyglutamate in catalysis by Escherichia coli DNA photolyase. The Journal of Biological Chemistry. 264: 9649-56. PMID 2656701  0.84
1988 Johnson JL, Hamm-Alvarez S, Payne G, Sancar GB, Rajagopalan KV, Sancar A. Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5,10-methenyltetrahydrofolate. Proceedings of the National Academy of Sciences of the United States of America. 85: 2046-50. PMID 2895469 DOI: 10.1073/pnas.85.7.2046  0.84
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