Brian N. Finck, Ph.D. - Publications

Affiliations: 
2000 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Animal Physiology Biology, Cell Biology, Molecular Biology

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Liss KHH, Ek SE, Lutkewitte AJ, Pietka TA, He M, Skaria P, Tycksen E, Ferguson D, Blanc V, Graham MJ, Hall AM, McGill MR, McCommis KS, Finck BN. Monoacylglycerol acyltransferase 1 knockdown exacerbates hepatic ischemia-reperfusion injury in mice with hepatic steatosis. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 32916011 DOI: 10.1002/Lt.25886  0.32
2020 Kading J, Finck BN, DeBosch BJ. Targeting hepatocyte carbohydrate transport to mimic fasting and calorie restriction. The Febs Journal. PMID 32654397 DOI: 10.1111/Febs.15482  0.333
2020 Chandran S, Schilke RM, Blackburn CMR, Yurochko A, Mirza R, Scott RS, Finck BN, Woolard MD. Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization. Frontiers in Immunology. 11: 787. PMID 32431707 DOI: 10.3389/Fimmu.2020.00787  0.33
2020 Lutkewitte AJ, Finck BN. 301-OR: Lipin 1–Mediated Phosphatidic Acid Phosphatase Activity in Adipocytes Regulates Systemic Insulin Sensitivity on High-Fat Diet Diabetes. 69. DOI: 10.2337/Db20-301-Or  0.397
2020 Martino MR, Aguilar MG, Mccommis KS, Yoshino J, Finck BN. 1860-P: Alanine Transaminase 2 Is Induced in Diabetic Liver and Contributes to Gluconeogenesis from Amino Acids Diabetes. 69. DOI: 10.2337/Db20-1860-P  0.406
2020 Jarasvaraparn C, Chan M, Daemen S, Schilling J, Chen Y, Finck B. Tu1655 THE EFFECT OF A NOVEL MITOCHONDRIAL PYRUVATE CARRIER INHIBITOR ON MARKERS OF LIVER INFLAMMATION AND FIBROSIS IN A MOUSE MODEL OF NONALCOHOLIC FATTY LIVER DISEASE Gastroenterology. 158: S-1440-S-1441. DOI: 10.1016/S0016-5085(20)34268-2  0.323
2019 Gao S, Ghoshal S, Zhang L, Stevens JR, McCommis KS, Finck BN, Lopaschuk GD, Butler AA. The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet-induced obesity. The Journal of Biological Chemistry. PMID 31324719 DOI: 10.1074/Jbc.Ra119.008967  0.317
2019 Cao T, Liccardo D, LaCanna R, Zhang X, Lu R, Finck BN, Leigh T, Chen X, Drosatos K, Tian Y. Fatty Acid Oxidation Promotes Cardiomyocyte Proliferation Rate but Does Not Change Cardiomyocyte Number in Infant Mice. Frontiers in Cell and Developmental Biology. 7: 42. PMID 30968022 DOI: 10.3389/Fcell.2019.00042  0.317
2019 Aatsinki SM, Elkhwanky MS, Kummu O, Karpale M, Buler M, Viitala P, Rinne V, Mutikainen M, Tavi P, Franko A, Wiesner RJ, Chambers KT, Finck BN, Hakkola J. Fasting-Induced Transcription Factors Repress Vitamin D Bioactivation, a Mechanism for Vitamin D Deficiency in Diabetes. Diabetes. PMID 30833469 DOI: 10.2337/Db18-1050  0.317
2019 Clemens MM, Kennon-McGill S, Apte U, James LP, Finck BN, McGill MR. The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. PMID 30654094 DOI: 10.1016/J.Fct.2019.01.014  0.312
2018 Finck BN. Targeting Metabolism, Insulin Resistance, and Diabetes to Treat Nonalcoholic Steatohepatitis. Diabetes. 67: 2485-2493. PMID 30459251 DOI: 10.2337/Dbi18-0024  0.368
2018 Sawicki KT, Chang HC, Shapiro JS, Bayeva M, De Jesus A, Finck BN, Wertheim JA, Blackshear PJ, Ardehali H. Hepatic tristetraprolin promotes insulin resistance through RNA destabilization of FGF21. Jci Insight. 3. PMID 29997282 DOI: 10.1172/Jci.Insight.95948  0.407
2018 Yan Z, Shyr ZA, Fortunato M, Welscher A, Alisio M, Martino M, Finck BN, Conway H, Remedi MS. High Fat Diet induced Remission of Diabetes in a subset of K -GOF Insulin Secretory-Deficient mice. Diabetes, Obesity & Metabolism. PMID 29896801 DOI: 10.1111/Dom.13423  0.345
2018 Liss KHH, Lutkewitte AJ, Pietka T, Finck BN, Franczyk M, Yoshino J, Klein S, Hall AM. Metabolic importance of adipose tissue monoacylglycerol acyltransferase 1 in mice and humans. Journal of Lipid Research. PMID 29853530 DOI: 10.1194/Jlr.M084947  0.384
2018 Liss KHH, McCommis KS, Chambers KT, Pietka TA, Schweitzer GG, Park SL, Nalbantoglu I, Weinheimer CJ, Hall AM, Finck BN. The impact of diet-induced hepatic steatosis in a murine model of hepatic ischemia-reperfusion injury. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 29729104 DOI: 10.1002/Lt.25189  0.313
2018 Lutkewitte AJ, Schweitzer GG, Kennon-McGill S, Clemens MM, James LP, Jaeschke H, Finck BN, McGill MR. Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. PMID 29534981 DOI: 10.1016/J.Fct.2018.03.014  0.332
2018 CHEN Y, CHAMBERS K, MCDONALD W, FINCK BN, MCCOMMIS KS. Identification and Characterization of a Novel Insulin Sensitizer to Treat Diabetes and Nonalcoholic Steatohepatitis Diabetes. 67: 237-LB. DOI: 10.2337/Db18-237-Lb  0.431
2018 MCCOMMIS KS, HODGES WT, CHEN Y, CHAMBERS K, FINCK BN. Identification of Mitochondrial Pyruvate Carrier Modulators to Treat Diabetes Diabetes. 67: 1770-P. DOI: 10.2337/Db18-1770-P  0.342
2017 Chen Y, McCommis KS, Ferguson D, Hall AM, Harris CA, Finck BN. Inhibition of the Mitochondrial Pyruvate Carrier by Tolylfluanid. Endocrinology. PMID 29126303 DOI: 10.1210/En.2017-00695  0.395
2017 Hall AM, Finck BN. ChREBP refines the hepatic response to fructose to protect the liver from injury. The Journal of Clinical Investigation. PMID 28628039 DOI: 10.1172/Jci95008  0.352
2017 Vigueira PA, McCommis KS, Hodges WT, Schweitzer GG, Cole SL, Oonthonpan L, Taylor EB, McDonald WG, Kletzien RF, Colca JR, Finck BN. The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism. Experimental Physiology. PMID 28597936 DOI: 10.1113/Ep086380  0.405
2016 McCommis KS, Hodges WT, Brunt EM, Nalbantoglu I, McDonald WG, Holley C, Fujiwara H, Schaffer JE, Colca JR, Finck BN. Targeting the Mitochondrial Pyruvate Carrier Attenuates Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis. Hepatology (Baltimore, Md.). PMID 28027586 DOI: 10.1002/Hep.29025  0.398
2016 Liss KH, Finck BN. PPARs and Nonalcoholic Fatty Liver Disease. Biochimie. PMID 27916647 DOI: 10.1016/J.Biochi.2016.11.009  0.348
2016 Wang J, Kim C, Jogasuria A, Han Y, Hu X, Wu J, Shen H, Chrast R, Finck BN, You M. Myeloid Cell-Specific Lipin-1 Deficiency Stimulates Endocrine Adiponectin-FGF15 Axis and Ameliorates Ethanol-Induced Liver Injury in Mice. Scientific Reports. 6: 34117. PMID 27666676 DOI: 10.1038/Srep34117  0.353
2016 McCommis KS, Hodges WT, Bricker DK, Wisidagama DR, Compan V, Remedi MS, Thummel CS, Finck BN. An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion. Molecular Metabolism. 5: 602-14. PMID 27656398 DOI: 10.1016/J.Molmet.2016.06.016  0.33
2016 Lam WY, Becker AM, Kennerly KM, Wong R, Curtis JD, Llufrio EM, McCommis KS, Fahrmann J, Pizzato HA, Nunley RM, Lee J, Wolfgang MJ, Patti GJ, Finck BN, Pearce EL, et al. Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells. Immunity. PMID 27396958 DOI: 10.1016/J.Immuni.2016.06.011  0.301
2016 DeBosch BJ, Heitmeier MR, Mayer AL, Higgins CB, Crowley JR, Kraft TE, Chi M, Newberry EP, Chen Z, Finck BN, Davidson NO, Yarasheski KE, Hruz PW, Moley KH. Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis. Science Signaling. 9: ra21. PMID 26905426 DOI: 10.1126/Scisignal.Aac5472  0.326
2015 McCommis KS, Chen Z, Fu X, McDonald WG, Colca JR, Kletzien RF, Burgess SC, Finck BN. Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling. Cell Metabolism. 22: 682-94. PMID 26344101 DOI: 10.1016/J.Cmet.2015.07.028  0.369
2015 Finck BN, Hall AM. Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance? Biomed Research International. 2015: 104132. PMID 26273583 DOI: 10.1155/2015/104132  0.355
2015 McCommis KS, Finck BN. Mitochondrial pyruvate transport: a historical perspective and future research directions. The Biochemical Journal. 466: 443-54. PMID 25748677 DOI: 10.1042/Bj20141171  0.31
2015 Schweitzer GG, Chen Z, Gan C, McCommis KS, Soufi N, Chrast R, Mitra MS, Yang K, Gross RW, Finck BN. Liver-specific loss of lipin-1-mediated phosphatidic acid phosphatase activity does not mitigate intrahepatic TG accumulation in mice. Journal of Lipid Research. 56: 848-58. PMID 25722343 DOI: 10.1194/Jlr.M055962  0.404
2014 Potthoff MJ, Finck BN. Head over hepatocytes for FGF21. Diabetes. 63: 4013-5. PMID 25414019 DOI: 10.2337/Db14-1185  0.381
2014 Soufi N, Hall AM, Chen Z, Yoshino J, Collier SL, Mathews JC, Brunt EM, Albert CJ, Graham MJ, Ford DA, Finck BN. Inhibiting monoacylglycerol acyltransferase 1 ameliorates hepatic metabolic abnormalities but not inflammation and injury in mice. The Journal of Biological Chemistry. 289: 30177-88. PMID 25213859 DOI: 10.1074/Jbc.M114.595850  0.407
2014 Devanathan S, Whitehead T, Schweitzer GG, Fettig N, Kovacs A, Korach KS, Finck BN, Shoghi KI. An animal model with a cardiomyocyte-specific deletion of estrogen receptor alpha: functional, metabolic, and differential network analysis. Plos One. 9: e101900. PMID 25000186 DOI: 10.1371/Journal.Pone.0101900  0.314
2014 Vigueira PA, McCommis KS, Schweitzer GG, Remedi MS, Chambers KT, Fu X, McDonald WG, Cole SL, Colca JR, Kletzien RF, Burgess SC, Finck BN. Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion. Cell Reports. 7: 2042-53. PMID 24910426 DOI: 10.1016/J.Celrep.2014.05.017  0.373
2014 Hall AM, Soufi N, Chambers KT, Chen Z, Schweitzer GG, McCommis KS, Erion DM, Graham MJ, Su X, Finck BN. Abrogating monoacylglycerol acyltransferase activity in liver improves glucose tolerance and hepatic insulin signaling in obese mice. Diabetes. 63: 2284-96. PMID 24595352 DOI: 10.2337/Db13-1502  0.407
2014 Debosch BJ, Chen Z, Saben JL, Finck BN, Moley KH. Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis. The Journal of Biological Chemistry. 289: 10989-98. PMID 24519932 DOI: 10.1074/Jbc.M113.527002  0.393
2013 Chambers KT, Chen Z, Lai L, Leone TC, Towle HC, Kralli A, Crawford PA, Finck BN. PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner. Molecular Metabolism. 2: 194-204. PMID 24049734 DOI: 10.1016/J.Molmet.2013.05.001  0.358
2013 DeBosch BJ, Chen Z, Finck BN, Chi M, Moley KH. Glucose transporter-8 (GLUT8) mediates glucose intolerance and dyslipidemia in high-fructose diet-fed male mice. Molecular Endocrinology (Baltimore, Md.). 27: 1887-96. PMID 24030250 DOI: 10.1210/Me.2013-1137  0.397
2013 Hu M, Yin H, Mitra MS, Liang X, Ajmo JM, Nadra K, Chrast R, Finck BN, You M. Hepatic-specific lipin-1 deficiency exacerbates experimental alcohol-induced steatohepatitis in mice. Hepatology (Baltimore, Md.). 58: 1953-63. PMID 23787969 DOI: 10.1002/Hep.26589  0.389
2013 Colca JR, McDonald WG, Cavey GS, Cole SL, Holewa DD, Brightwell-Conrad AS, Wolfe CL, Wheeler JS, Coulter KR, Kilkuskie PM, Gracheva E, Korshunova Y, Trusgnich M, Karr R, Wiley SE, ... ... Finck BN, et al. Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins. Plos One. 8: e61551. PMID 23690925 DOI: 10.1371/Journal.Pone.0061551  0.339
2013 Magkos F, Bradley D, Schweitzer GG, Finck BN, Eagon JC, Ilkayeva O, Newgard CB, Klein S. Effect of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding on branched-chain amino acid metabolism. Diabetes. 62: 2757-61. PMID 23610059 DOI: 10.2337/Db13-0185  0.323
2013 Fabbrini E, Cella M, McCartney SA, Fuchs A, Abumrad NA, Pietka TA, Chen Z, Finck BN, Han DH, Magkos F, Conte C, Bradley D, Fraterrigo G, Eagon JC, Patterson BW, et al. Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals. Gastroenterology. 145: 366-74.e1-3. PMID 23597726 DOI: 10.1053/J.Gastro.2013.04.010  0.317
2013 Mitra MS, Chen Z, Ren H, Harris TE, Chambers KT, Hall AM, Nadra K, Klein S, Chrast R, Su X, Morris AJ, Finck BN. Mice with an adipocyte-specific lipin 1 separation-of-function allele reveal unexpected roles for phosphatidic acid in metabolic regulation. Proceedings of the National Academy of Sciences of the United States of America. 110: 642-7. PMID 23267081 DOI: 10.1073/Pnas.1213493110  0.377
2012 Chambers KT, Chen Z, Crawford PA, Fu X, Burgess SC, Lai L, Leone TC, Kelly DP, Finck BN. Liver-specific PGC-1beta deficiency leads to impaired mitochondrial function and lipogenic response to fasting-refeeding. Plos One. 7: e52645. PMID 23285128 DOI: 10.1371/Journal.Pone.0052645  0.401
2012 Chen Z, Gropler MC, Mitra MS, Finck BN. Complex interplay between the lipin 1 and the hepatocyte nuclear factor 4 α (HNF4α) pathways to regulate liver lipid metabolism. Plos One. 7: e51320. PMID 23236470 DOI: 10.1371/Journal.Pone.0051320  0.362
2012 Wang S, Chen Z, Lam V, Han J, Hassler J, Finck BN, Davidson NO, Kaufman RJ. IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis. Cell Metabolism. 16: 473-86. PMID 23040069 DOI: 10.1016/J.Cmet.2012.09.003  0.361
2012 Solingapuram Sai KK, Kil KE, Tu Z, Chu W, Finck BN, Rothfuss JM, Shoghi KI, Welch MJ, Gropler RJ, Mach RH. Synthesis, radiolabeling and initial in vivo evaluation of [(11)C]KSM-01 for imaging PPAR-α receptors. Bioorganic & Medicinal Chemistry Letters. 22: 6233-6. PMID 22939697 DOI: 10.1016/J.Bmcl.2012.08.010  0.319
2012 Chen Z, Vigueira PA, Chambers KT, Hall AM, Mitra MS, Qi N, McDonald WG, Colca JR, Kletzien RF, Finck BN. Insulin resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor γ-sparing thiazolidinedione. The Journal of Biological Chemistry. 287: 23537-48. PMID 22621923 DOI: 10.1074/Jbc.M112.363960  0.413
2012 Finck BN. A sweet new role for ubiquitin-specific protease 2 in controlling hepatic gluconeogenesis. Diabetes. 61: 993-4. PMID 22517656 DOI: 10.2337/Db12-0198  0.367
2012 Hall AM, Kou K, Chen Z, Pietka TA, Kumar M, Korenblat KM, Lee K, Ahn K, Fabbrini E, Klein S, Goodwin B, Finck BN. Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver. Journal of Lipid Research. 53: 990-9. PMID 22394502 DOI: 10.1194/Jlr.P025536  0.357
2012 Hu M, Wang F, Li X, Rogers CQ, Liang X, Finck BN, Mitra MS, Zhang R, Mitchell DA, You M. Regulation of hepatic lipin-1 by ethanol: role of AMP-activated protein kinase/sterol regulatory element-binding protein 1 signaling in mice. Hepatology (Baltimore, Md.). 55: 437-46. PMID 21953514 DOI: 10.1002/Hep.24708  0.321
2011 Gan Z, Burkart-Hartman EM, Han DH, Finck B, Leone TC, Smith EY, Ayala JE, Holloszy J, Kelly DP. The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2. Genes & Development. 25: 2619-30. PMID 22135324 DOI: 10.1101/Gad.178434.111  0.342
2011 Peterson TR, Sengupta SS, Harris TE, Carmack AE, Kang SA, Balderas E, Guertin DA, Madden KL, Carpenter AE, Finck BN, Sabatini DM. mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway. Cell. 146: 408-20. PMID 21816276 DOI: 10.1016/J.Cell.2011.06.034  0.36
2011 Potthoff MJ, Boney-Montoya J, Choi M, He T, Sunny NE, Satapati S, Suino-Powell K, Xu HE, Gerard RD, Finck BN, Burgess SC, Mangelsdorf DJ, Kliewer SA. FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1α pathway. Cell Metabolism. 13: 729-38. PMID 21641554 DOI: 10.1016/J.Cmet.2011.03.019  0.39
2011 Mitra MS, Schilling JD, Wang X, Jay PY, Huss JM, Su X, Finck BN. Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis. Journal of Molecular and Cellular Cardiology. 51: 120-8. PMID 21549711 DOI: 10.1016/J.Yjmcc.2011.04.009  0.362
2011 Harris TE, Finck BN. Dual function lipin proteins and glycerolipid metabolism. Trends in Endocrinology and Metabolism: Tem. 22: 226-33. PMID 21470873 DOI: 10.1016/J.Tem.2011.02.006  0.301
2011 Chambers KT, Leone TC, Sambandam N, Kovacs A, Wagg CS, Lopaschuk GD, Finck BN, Kelly DP. Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response. The Journal of Biological Chemistry. 286: 11155-62. PMID 21321124 DOI: 10.1074/Jbc.M110.217349  0.386
2010 Gazit V, Weymann A, Hartman E, Finck BN, Hruz PW, Tzekov A, Rudnick DA. Liver regeneration is impaired in lipodystrophic fatty liver dystrophy mice. Hepatology (Baltimore, Md.). 52: 2109-17. PMID 20967828 DOI: 10.1002/Hep.23920  0.361
2010 Chen Z, Norris JY, Finck BN. Peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) stimulates VLDL assembly through activation of cell death-inducing DFFA-like effector B (CideB). The Journal of Biological Chemistry. 285: 25996-6004. PMID 20551328 DOI: 10.1074/Jbc.M110.141598  0.394
2010 Kars M, Yang L, Gregor MF, Mohammed BS, Pietka TA, Finck BN, Patterson BW, Horton JD, Mittendorfer B, Hotamisligil GS, Klein S. Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes. 59: 1899-905. PMID 20522594 DOI: 10.2337/Db10-0308  0.338
2010 Kim HB, Kumar A, Wang L, Liu GH, Keller SR, Lawrence JC, Finck BN, Harris TE. Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factors. Molecular and Cellular Biology. 30: 3126-39. PMID 20385772 DOI: 10.1128/Mcb.01671-09  0.373
2010 Hall AM, Brunt EM, Chen Z, Viswakarma N, Reddy JK, Wolins NE, Finck BN. Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice. Journal of Lipid Research. 51: 554-63. PMID 19749180 DOI: 10.1194/Jlr.M000976  0.379
2009 Potthoff MJ, Inagaki T, Satapati S, Ding X, He T, Goetz R, Mohammadi M, Finck BN, Mangelsdorf DJ, Kliewer SA, Burgess SC. FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response. Proceedings of the National Academy of Sciences of the United States of America. 106: 10853-8. PMID 19541642 DOI: 10.1073/Pnas.0904187106  0.416
2009 Kirk E, Reeds DN, Finck BN, Mayurranjan SM, Mayurranjan MS, Patterson BW, Klein S. Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction. Gastroenterology. 136: 1552-60. PMID 19208352 DOI: 10.1053/J.Gastro.2009.01.048  0.342
2009 Gropler MC, Harris TE, Hall AM, Wolins NE, Gross RW, Han X, Chen Z, Finck BN. Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice. The Journal of Biological Chemistry. 284: 6763-72. PMID 19136718 DOI: 10.1074/Jbc.M807882200  0.389
2008 Chen Z, Gropler MC, Norris J, Lawrence JC, Harris TE, Finck BN. Alterations in hepatic metabolism in fld mice reveal a role for lipin 1 in regulating VLDL-triacylglyceride secretion. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1738-44. PMID 18669885 DOI: 10.1161/Atvbaha.108.171538  0.432
2008 Shoghi KI, Gropler RJ, Sharp T, Herrero P, Fettig N, Su Y, Mitra MS, Kovacs A, Finck BN, Welch MJ. Time course of alterations in myocardial glucose utilization in the Zucker diabetic fatty rat with correlation to gene expression of glucose transporters: a small-animal PET investigation. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 1320-7. PMID 18632819 DOI: 10.2967/Jnumed.108.051672  0.306
2008 Marionneau C, Aimond F, Brunet S, Niwa N, Finck B, Kelly DP, Nerbonne JM. PPARalpha-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 44: 1002-15. PMID 18482733 DOI: 10.1016/J.Yjmcc.2008.03.023  0.33
2008 Duncan JG, Finck BN. The PPARalpha-PGC-1alpha Axis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium. Ppar Research. 2008: 253817. PMID 18288281 DOI: 10.1155/2008/253817  0.373
2007 Croce MA, Eagon JC, LaRiviere LL, Korenblat KM, Klein S, Finck BN. Hepatic lipin 1beta expression is diminished in insulin-resistant obese subjects and is reactivated by marked weight loss. Diabetes. 56: 2395-9. PMID 17563064 DOI: 10.2337/Db07-0480  0.371
2007 Finck BN, Kelly DP. Peroxisome proliferator-activated receptor gamma coactivator-1 (PGC-1) regulatory cascade in cardiac physiology and disease. Circulation. 115: 2540-8. PMID 17502589 DOI: 10.1161/Circulationaha.107.670588  0.339
2007 Coughlin CC, Finck BN, Eagon JC, Halpin VJ, Magkos F, Mohammed BS, Klein S. Effect of marked weight loss on adiponectin gene expression and plasma concentrations. Obesity (Silver Spring, Md.). 15: 640-5. PMID 17372314 DOI: 10.1038/Oby.2007.556  0.311
2007 Yang J, Sambandam N, Han X, Gross RW, Courtois M, Kovacs A, Febbraio M, Finck BN, Kelly DP. CD36 deficiency rescues lipotoxic cardiomyopathy. Circulation Research. 100: 1208-17. PMID 17363697 DOI: 10.1161/01.Res.0000264104.25265.B6  0.345
2007 Duncan JG, Fong JL, Medeiros DM, Finck BN, Kelly DP. Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway. Circulation. 115: 909-17. PMID 17261654 DOI: 10.1161/Circulationaha.106.662296  0.388
2007 Finck BN. The PPAR regulatory system in cardiac physiology and disease. Cardiovascular Research. 73: 269-77. PMID 17010956 DOI: 10.1016/J.Cardiores.2006.08.023  0.361
2006 Wolins NE, Quaynor BK, Skinner JR, Tzekov A, Croce MA, Gropler MC, Varma V, Yao-Borengasser A, Rasouli N, Kern PA, Finck BN, Bickel PE. OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization. Diabetes. 55: 3418-28. PMID 17130488 DOI: 10.2337/Db06-0399  0.392
2006 Schneider JG, Finck BN, Ren J, Standley KN, Takagi M, Maclean KH, Bernal-Mizrachi C, Muslin AJ, Kastan MB, Semenkovich CF. ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome. Cell Metabolism. 4: 377-89. PMID 17084711 DOI: 10.1016/J.Cmet.2006.10.002  0.368
2006 Finck BN, Gropler MC, Chen Z, Leone TC, Croce MA, Harris TE, Lawrence JC, Kelly DP. Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway. Cell Metabolism. 4: 199-210. PMID 16950137 DOI: 10.1016/J.Cmet.2006.08.005  0.421
2006 Burgess SC, Leone TC, Wende AR, Croce MA, Chen Z, Sherry AD, Malloy CR, Finck BN. Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice. The Journal of Biological Chemistry. 281: 19000-8. PMID 16670093 DOI: 10.1074/Jbc.M600050200  0.411
2006 Finck BN, Kelly DP. PGC-1 coactivators: inducible regulators of energy metabolism in health and disease. The Journal of Clinical Investigation. 116: 615-22. PMID 16511594 DOI: 10.1172/Jci27794  0.354
2006 Finck BN. Effects of PPARalpha on cardiac glucose metabolism: a transcriptional equivalent of the glucose-fatty acid cycle? Expert Review of Cardiovascular Therapy. 4: 161-71. PMID 16509812 DOI: 10.1586/14779072.4.2.161  0.395
2005 Park SY, Cho YR, Finck BN, Kim HJ, Higashimori T, Hong EG, Lee MK, Danton C, Deshmukh S, Cline GW, Wu JJ, Bennett AM, Rothermel B, Kalinowski A, Russell KS, et al. Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver. Diabetes. 54: 2514-24. PMID 16123338 DOI: 10.2337/Diabetes.54.9.2514  0.39
2005 Finck BN, Bernal-Mizrachi C, Han DH, Coleman T, Sambandam N, LaRiviere LL, Holloszy JO, Semenkovich CF, Kelly DP. A potential link between muscle peroxisome proliferator- activated receptor-alpha signaling and obesity-related diabetes. Cell Metabolism. 1: 133-44. PMID 16054054 DOI: 10.1016/J.Cmet.2005.01.006  0.411
2005 Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, et al. PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. Plos Biology. 3: e101. PMID 15760270 DOI: 10.1371/Journal.Pbio.0030101  0.394
2005 Russell LK, Finck BN, Kelly DP. Mouse models of mitochondrial dysfunction and heart failure. Journal of Molecular and Cellular Cardiology. 38: 81-91. PMID 15623424 DOI: 10.1016/J.Yjmcc.2004.10.010  0.305
2004 Harris IS, Treskov I, Rowley MW, Heximer S, Kaltenbronn K, Finck BN, Gross RW, Kelly DP, Blumer KJ, Muslin AJ. G-protein signaling participates in the development of diabetic cardiomyopathy. Diabetes. 53: 3082-90. PMID 15561937 DOI: 10.2337/Diabetes.53.12.3082  0.37
2004 Finck BN. The role of the peroxisome proliferator-activated receptor alpha pathway in pathological remodeling of the diabetic heart. Current Opinion in Clinical Nutrition and Metabolic Care. 7: 391-6. PMID 15192440 DOI: 10.1097/01.Mco.0000134371.70815.32  0.309
2003 Bernal-Mizrachi C, Weng S, Feng C, Finck BN, Knutsen RH, Leone TC, Coleman T, Mecham RP, Kelly DP, Semenkovich CF. Dexamethasone induction of hypertension and diabetes is PPAR-alpha dependent in LDL receptor-null mice. Nature Medicine. 9: 1069-75. PMID 12847522 DOI: 10.1038/Nm898  0.432
2003 Finck BN, Han X, Courtois M, Aimond F, Nerbonne JM, Kovacs A, Gross RW, Kelly DP. A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content. Proceedings of the National Academy of Sciences of the United States of America. 100: 1226-31. PMID 12552126 DOI: 10.1073/Pnas.0336724100  0.355
2002 Finck BN, Kelly DP. Peroxisome proliferator-activated receptor alpha (PPARalpha) signaling in the gene regulatory control of energy metabolism in the normal and diseased heart. Journal of Molecular and Cellular Cardiology. 34: 1249-57. PMID 12425323 DOI: 10.1006/Jmcc.2002.2061  0.367
2002 Finck BN, Johnson RW. Anti-inflammatory agents inhibit the induction of leptin by tumor necrosis factor-alpha. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 282: R1429-35. PMID 11959686 DOI: 10.1152/Ajpregu.00569.2001  0.533
2002 Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, Kovacs A, Han X, Gross RW, Kozak R, Lopaschuk GD, Kelly DP. The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. The Journal of Clinical Investigation. 109: 121-30. PMID 11781357 DOI: 10.1172/Jci14080  0.367
2001 Johnson RW, Finck BN. Tumor necrosis factor α and leptin: Two players in an animal's metabolic and immunologic responses to infection Journal of Animal Science. 79: E118. DOI: 10.2527/Jas2001.79E-Supple118X  0.479
2000 Finck BN, Johnson RW. Tumor necrosis factor-alpha regulates secretion of the adipocyte-derived cytokine, leptin. Microscopy Research and Technique. 50: 209-15. PMID 10891886 DOI: 10.1002/1097-0029(20000801)50:3<209::Aid-Jemt4>3.0.Co;2-T  0.526
2000 Heyen JR, Ye S, Finck BN, Johnson RW. Interleukin (IL)-10 inhibits IL-6 production in microglia by preventing activation of NF-kappaB. Brain Research. Molecular Brain Research. 77: 138-47. PMID 10814840 DOI: 10.1016/S0169-328X(00)00042-5  0.469
2000 Finck BN, Johnson RW. Tumor necrosis factor (TNF)-alpha induces leptin production through the p55 TNF receptor. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 278: R537-43. PMID 10666158 DOI: 10.1152/Ajpregu.2000.278.2.R537  0.531
1999 Finck BN, Johnson RW. Intracerebroventricular injection of lipopolysaccharide increases plasma leptin levels. Neuroreport. 10: 153-6. PMID 10094153 DOI: 10.1097/00001756-199901180-00029  0.51
1998 Finck BN, Kelley KW, Dantzer R, Johnson RW. In Vivo and in Vitro Evidence for the Involvement of Tumor Necrosis Factor-α in the Induction of Leptin by Lipopolysaccharide. Endocrinology. 139: 2278-2283. PMID 28200544 DOI: 10.1210/endo.139.5.6012  0.558
1998 Finck BN, Kelley KW, Dantzer R, Johnson RW. In vivo and in vitro evidence for the involvement of tumor necrosis factor-alpha in the induction of leptin by lipopolysaccharide. Endocrinology. 139: 2278-83. PMID 9564834 DOI: 10.1210/Endo.139.5.6012  0.64
1997 Finck BN, Johnson RW. Anorexia, weight loss and increased plasma interleukin-6 caused by chronic intracerebroventricular infusion of interleukin-1beta in the rat. Brain Research. 761: 333-7. PMID 9252034 DOI: 10.1016/S0006-8993(97)00451-4  0.446
1997 Webel DM, Finck BN, Baker DH, Johnson RW. Time course of increased plasma cytokines, cortisol, and urea nitrogen in pigs following intraperitoneal injection of lipopolysaccharide. Journal of Animal Science. 75: 1514-20. PMID 9250511 DOI: 10.2527/1997.7561514X  0.517
1997 Finck BN, Dantzer R, Kelley KW, Woods JA, Johnson RW. Central lipopolysaccharide elevates plasma IL-6 concentration by an alpha-adrenoreceptor-mediated mechanism. The American Journal of Physiology. 272: R1880-7. PMID 9227603 DOI: 10.1152/Ajpregu.1997.272.6.R1880  0.617
1997 Warren EJ, Finck BN, Arkins S, Kelley KW, Scamurra RW, Murtaugh MP, Johnson RW. Coincidental changes in behavior and plasma cortisol in unrestrained pigs after intracerebroventricular injection of tumor necrosis factor-alpha. Endocrinology. 138: 2365-71. PMID 9165024 DOI: 10.1210/Endo.138.6.5180  0.614
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