| Year |
Citation |
Score |
| 2020 |
Spangle JM, Von T, Pavlick DC, Khotimsky A, Zhao JJ, Roberts TM. PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition. Proceedings of the National Academy of Sciences of the United States of America. PMID 32929011 DOI: 10.1073/Pnas.2000060117 |
0.325 |
|
| 2017 |
Thorpe LM, Spangle JM, Ohlson CE, Cheng H, Roberts TM, Cantley LC, Zhao JJ. PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α. Proceedings of the National Academy of Sciences of the United States of America. PMID 28630349 DOI: 10.1073/Pnas.1704706114 |
0.337 |
|
| 2017 |
Spangle JM, Roberts TM. Epigenetic regulation of RTK signaling. Journal of Molecular Medicine (Berlin, Germany). PMID 28589435 DOI: 10.1007/S00109-017-1546-0 |
0.378 |
|
| 2017 |
Spangle JM, Roberts TM, Zhao JJ. The emerging role of PI3K/AKT-mediated epigenetic regulation in cancer. Biochimica Et Biophysica Acta. PMID 28315368 DOI: 10.1016/J.Bbcan.2017.03.002 |
0.391 |
|
| 2016 |
Spangle JM, Dreijerink KM, Groner AC, Cheng H, Ohlson CE, Reyes J, Lin CY, Bradner J, Zhao JJ, Roberts TM, Brown M. PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer. Cell Reports. PMID 27292631 DOI: 10.1016/J.Celrep.2016.05.046 |
0.377 |
|
| 2015 |
Wang Q, Liu P, Spangle JM, Von T, Roberts TM, Lin NU, Krop IE, Winer EP, Zhao JJ. PI3K-p110α mediates resistance to HER2-targeted therapy in HER2+, PTEN-deficient breast cancers. Oncogene. PMID 26500061 DOI: 10.1038/Onc.2015.406 |
0.348 |
|
| 2014 |
Spangle JM, Chen AA, Munger K. Human papillomavirus: Pathogenesis and host immune response Viruses and Human Cancer. 167-197. DOI: 10.1007/978-1-4939-0870-7_8 |
0.647 |
|
| 2013 |
Spangle JM, Munger K. The HPV16 E6 oncoprotein causes prolonged receptor protein tyrosine kinase signaling and enhances internalization of phosphorylated receptor species. Plos Pathogens. 9: e1003237. PMID 23516367 DOI: 10.1371/Journal.Ppat.1003237 |
0.662 |
|
| 2013 |
Meyers JM, Spangle JM, Munger K. The human papillomavirus type 8 E6 protein interferes with NOTCH activation during keratinocyte differentiation. Journal of Virology. 87: 4762-7. PMID 23365452 DOI: 10.1128/Jvi.02527-12 |
0.652 |
|
| 2012 |
Rozenblatt-Rosen O, Deo RC, Padi M, Adelmant G, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR, Chen AA, ... ... Spangle JM, et al. Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins. Nature. 487: 491-5. PMID 22810586 DOI: 10.1038/Nature11288 |
0.561 |
|
| 2012 |
Spangle JM, Ghosh-Choudhury N, Munger K. Activation of cap-dependent translation by mucosal human papillomavirus E6 proteins is dependent on the integrity of the LXXLL binding motif. Journal of Virology. 86: 7466-72. PMID 22553330 DOI: 10.1128/Jvi.00487-12 |
0.643 |
|
| 2010 |
Spangle JM, Münger K. The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis. Journal of Virology. 84: 9398-407. PMID 20631133 DOI: 10.1128/Jvi.00974-10 |
0.658 |
|
| 2009 |
Zhou X, Spangle JM, Münger K. Expression of a viral oncoprotein in normal human epithelial cells triggers an autophagy-related process: is autophagy an "Achilles' heel" of human cancers? Autophagy. 5: 578-9. PMID 19333004 DOI: 10.4161/Auto.5.4.8367 |
0.59 |
|
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