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Todd T. Talley, Ph.D. - Publications

Affiliations: 
2007-2012 University of California, San Diego, La Jolla, CA 
 2012-2017 College of Western Idaho 
 2012-2017 Idaho State University, Pocatello, ID, United States 
Area:
Organic Chemistry, Toxicology
Website:
https://toddtalley.net/
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Kem WR, Andrud K, Bruno G, Xing H, Soti F, Talley TT, Taylor P. Interactions of Nereistoxin and Its Analogs with Vertebrate Nicotinic Acetylcholine Receptors and Molluscan ACh Binding Proteins. Marine Drugs. 20. PMID 35049904 DOI: 10.3390/md20010049  0.666
2020 Talley TT, Chao CK, Berkman CE, Richardson RJ, Thompson CM. Inhibition of acetylcholinesterases by stereoisomeric organophosphorus compounds containing both thioester and p-nitrophenyl leaving groups. Chemical Research in Toxicology. PMID 32833441 DOI: 10.1021/Acs.Chemrestox.0C00236  0.656
2018 Hone AJ, Talley TT, Bobango J, Huidobro Melo C, Hararah F, Gajewiak JB, Christensen SB, Harvey PJ, Craik DJ, McIntosh JM. Molecular determinants of α-conotoxin potency for inhibition of human and rat α6β4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. PMID 30249616 DOI: 10.1074/Jbc.Ra118.005649  0.456
2015 Bobango J, Denton TT, Talley TT. A survey of high resolution AChBP X-ray structures reveals details of tertiary and quaternary movements of the protein, both real and imagined, upon ligand binding Biochemical Pharmacology. 97: 628. DOI: 10.1016/J.Bcp.2015.08.022  0.685
2015 Bobango J, Wensel S, Hunt J, Amerhamzeh J, Estep K, Talley TT. Engineered acetylcholine binding proteins to explore ligand recognition and specificity Biochemical Pharmacology. 97: 627-628. DOI: 10.1016/J.Bcp.2015.08.021  0.507
2014 Bourne Y, Sulzenbacher G, Radić Z, Aráoz R, Reynaud M, Benoit E, Talley T, Zakarian A, Taylor P, Servent D, Molgó J, Marchot P. 18. Diversity in the binding interactions of marine toxins to AChBP, the soluble nAChR surrogate Toxicon. 91: 171-172. DOI: 10.1016/J.Toxicon.2014.08.026  0.64
2013 Rodríguez LP, Vilariño N, Molgó J, Aráoz R, Louzao MC, Taylor P, Talley T, Botana LM. Development of a solid-phase receptor-based assay for the detection of cyclic imines using a microsphere-flow cytometry system. Analytical Chemistry. 85: 2340-7. PMID 23343192 DOI: 10.1021/Ac3033432  0.639
2012 Yamauchi JG, Gomez K, Grimster N, Dufouil M, Nemecz A, Fotsing JR, Ho KY, Talley TT, Sharpless KB, Fokin VV, Taylor P. Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates. Molecular Pharmacology. 82: 687-99. PMID 22784805 DOI: 10.1124/Mol.112.080291  0.679
2012 Rojsanga P, Boonyarat C, Utsintong M, Nemecz Á, Yamauchi JG, Talley TT, Olson AJ, Matsumoto K, Vajragupta O. The effect of crebanine on memory and cognition impairment via the alpha-7 nicotinic acetylcholine receptor. Life Sciences. 91: 107-14. PMID 22749860 DOI: 10.1016/J.Lfs.2012.06.017  0.321
2012 Grimster NP, Stump B, Fotsing JR, Weide T, Talley TT, Yamauchi JG, Nemecz Á, Kim C, Ho KY, Sharpless KB, Taylor P, Fokin VV. Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template. Journal of the American Chemical Society. 134: 6732-40. PMID 22394239 DOI: 10.1021/Ja3001858  0.743
2012 Utsintong M, Rojsanga P, Ho KY, Talley TT, Olson AJ, Matsumoto K, Vajragupta O. Virtual screening against acetylcholine binding protein. Journal of Biomolecular Screening. 17: 204-15. PMID 21956172 DOI: 10.1177/1087057111421667  0.565
2011 Kombo DC, Mazurov A, Tallapragada K, Hammond PS, Chewning J, Hauser TA, Vasquez-Valdivieso M, Yohannes D, Talley TT, Taylor P, Caldwell WS. Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands. European Journal of Medicinal Chemistry. 46: 5625-35. PMID 21986237 DOI: 10.1016/J.Ejmech.2011.09.033  0.681
2011 Yamauchi JG, Nemecz Á, Nguyen QT, Muller A, Schroeder LF, Talley TT, Lindstrom J, Kleinfeld D, Taylor P. Characterizing ligand-gated ion channel receptors with genetically encoded Ca2++ sensors. Plos One. 6: e16519. PMID 21305050 DOI: 10.1371/Journal.Pone.0016519  0.559
2011 Talley TT, Nemecz A, Yamauchi JG, Wu J, Ho K, Sankaran B, Taylor P. Acetylcholine binding protein-nicotinic receptor chimeras for delineating structure and determinants of ligand selectivity Biochemical Pharmacology. 82: 1028-1029. DOI: 10.1016/J.Bcp.2011.07.018  0.738
2010 Bourne Y, Radic Z, Aráoz R, Talley TT, Benoit E, Servent D, Taylor P, Molgó J, Marchot P. Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism. Proceedings of the National Academy of Sciences of the United States of America. 107: 6076-81. PMID 20224036 DOI: 10.1073/Pnas.0912372107  0.723
2010 Srivastava S, Hamouda AK, Talley TT, Pandhare A, Duddempudi PK, Hsiao H, Taylor P, Cohen JB, Blanton MP. Photoaffinity Labeling the Agonist Binding Sites of Torpedo and α4β2 Nicotinic Acetylcholine Receptors and Acetylcholine Binding Proteins (AChBPs) with [3H]Cytisine Biophysical Journal. 98: 130a-131a. DOI: 10.1016/J.Bpj.2009.12.706  0.684
2009 Utsintong M, Talley TT, Taylor PW, Olson AJ, Vajragupta O. Virtual screening against alpha-cobratoxin. Journal of Biomolecular Screening. 14: 1109-18. PMID 19734437 DOI: 10.1177/1087057109344617  0.687
2009 Hibbs RE, Sulzenbacher G, Shi J, Talley TT, Conrod S, Kem WR, Taylor P, Marchot P, Bourne Y. Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor. The Embo Journal. 28: 3040-51. PMID 19696737 DOI: 10.1038/Emboj.2009.227  0.811
2009 Rana BK, Wessel J, Mahboubi V, Rao F, Haeller J, Gayen JR, Eskin E, Valle AM, Das M, Mahata SK, Taupenot L, Stridsberg M, Talley TT, Ziegler MG, Smith DW, et al. Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: influence on heritable autonomic traits in twin pairs. The Journal of Pharmacology and Experimental Therapeutics. 331: 419-28. PMID 19671882 DOI: 10.1124/Jpet.109.157271  0.568
2009 Tomizawa M, Talley TT, Park JF, Maltby D, Medzihradszky KF, Durkin KA, Cornejo-Bravo JM, Burlingame AL, Casida JE, Taylor P. Nicotinic agonist binding site mapped by methionine- and tyrosine-scanning coupled with azidochloropyridinyl photoaffinity labeling. Journal of Medicinal Chemistry. 52: 3735-41. PMID 19459645 DOI: 10.1021/Jm900153C  0.701
2009 Babakhani A, Talley TT, Taylor P, McCammon JA. A virtual screening study of the acetylcholine binding protein using a relaxed-complex approach. Computational Biology and Chemistry. 33: 160-70. PMID 19186108 DOI: 10.1016/J.Compbiolchem.2008.12.002  0.699
2008 Talley TT, Harel M, Hibbs RE, Radic Z, Tomizawa M, Casida JE, Taylor P. Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore. Proceedings of the National Academy of Sciences of the United States of America. 105: 7606-11. PMID 18477694 DOI: 10.1073/Pnas.0802197105  0.825
2008 Tomizawa M, Maltby D, Talley TT, Durkin KA, Medzihradszky KF, Burlingame AL, Taylor P, Casida JE. Atypical nicotinic agonist bound conformations conferring subtype selectivity. Proceedings of the National Academy of Sciences of the United States of America. 105: 1728-32. PMID 18230720 DOI: 10.1073/Pnas.0711724105  0.669
2007 Taylor P, Talley TT, Radic' Z, Hansen SB, Hibbs RE, Shi J. Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes. Biochemical Pharmacology. 74: 1164-71. PMID 17826748 DOI: 10.1016/J.Bcp.2007.07.038  0.818
2007 Tomizawa M, Maltby D, Medzihradszky KF, Zhang N, Durkin KA, Presley J, Talley TT, Taylor P, Burlingame AL, Casida JE. Defining nicotinic agonist binding surfaces through photoaffinity labeling. Biochemistry. 46: 8798-806. PMID 17614369 DOI: 10.1021/Bi700667V  0.724
2007 Tomizawa M, Talley TT, Maltby D, Durkin KA, Medzihradszky KF, Burlingame AL, Taylor P, Casida JE. Mapping the elusive neonicotinoid binding site. Proceedings of the National Academy of Sciences of the United States of America. 104: 9075-80. PMID 17485662 DOI: 10.1073/Pnas.0703309104  0.728
2007 Kang TS, Radi? Z, Talley TT, Jois SD, Taylor P, Kini RM. Protein folding determinants: structural features determining alternative disulfide pairing in alpha- and chi/lambda-conotoxins. Biochemistry. 46: 3338-55. PMID 17315952 DOI: 10.1021/Bi061969O  0.583
2006 Bourne Y, Hansen SB, Sulzenbacher G, Talley TT, Huxford T, Taylor P, Marchot P. Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein. Journal of Molecular Neuroscience : Mn. 30: 103-4. PMID 17192648 DOI: 10.1385/Jmn:30:1:103  0.702
2006 Talley TT, Yalda S, Ho KY, Tor Y, Soti FS, Kem WR, Taylor P. Spectroscopic analysis of benzylidene anabaseine complexes with acetylcholine binding proteins as models for ligand-nicotinic receptor interactions. Biochemistry. 45: 8894-902. PMID 16846232 DOI: 10.1021/Bi060534Y  0.716
2006 Talley TT, Olivera BM, Han KH, Christensen SB, Dowell C, Tsigelny I, Ho KY, Taylor P, McIntosh JM. Alpha-conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as alpha3beta2 and alpha7 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 281: 24678-86. PMID 16803900 DOI: 10.1074/Jbc.M602969200  0.665
2006 Radić Z, Talley TT, Hansen SB, Yu W, Taylor P. Interaction of organophosphate and carbamate cholinesterase inhibitors with acetylcholine binding proteins Toxicology Letters. 164: S239. DOI: 10.1016/J.Toxlet.2006.07.157  0.708
2005 Bourne Y, Talley TT, Hansen SB, Taylor P, Marchot P. Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors. The Embo Journal. 24: 1512-22. PMID 15791209 DOI: 10.1038/Sj.Emboj.7600620  0.772
2004 Hibbs RE, Talley TT, Taylor P. Acrylodan-conjugated cysteine side chains reveal conformational state and ligand site locations of the acetylcholine-binding protein. The Journal of Biological Chemistry. 279: 28483-91. PMID 15117947 DOI: 10.1074/Jbc.M403713200  0.796
2004 Hansen SB, Talley TT, Radic Z, Taylor P. Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica. The Journal of Biological Chemistry. 279: 24197-202. PMID 15069068 DOI: 10.1074/Jbc.M402452200  0.762
2004 Taylor P, Hansen SB, Talley TT, Hibbs RE, Radi? Z. Contemporary paradigms for cholinergic ligand design guided by biological structure. Bioorganic & Medicinal Chemistry Letters. 14: 1875-7. PMID 15050619 DOI: 10.1016/J.Bmcl.2003.10.072  0.796
2003 Gao F, Bern N, Little A, Wang HL, Hansen SB, Talley TT, Taylor P, Sine SM. Curariform antagonists bind in different orientations to acetylcholine-binding protein. The Journal of Biological Chemistry. 278: 23020-6. PMID 12682067 DOI: 10.1074/Jbc.M301151200  0.799
2002 Hansen SB, Radic' Z, Talley TT, Molles BE, Deerinck T, Tsigelny I, Taylor P. Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein. The Journal of Biological Chemistry. 277: 41299-302. PMID 12235129 DOI: 10.1074/Jbc.C200462200  0.796
2001 Doorn JA, Schall M, Gage DA, Talley TT, Thompson CM, Richardson RJ. Identification of butyrylcholinesterase adducts after inhibition with isomalathion using mass spectrometry: difference in mechanism between (1R)- and (1S)-stereoisomers. Toxicology and Applied Pharmacology. 176: 73-80. PMID 11601883 DOI: 10.1006/Taap.2001.9279  0.467
2001 Doorn JA, Talley TT, Thompson CM, Richardson RJ. Probing the active sites of butyrylcholinesterase and cholesterol esterase with isomalathion: conserved stereoselective inactivation of serine hydrolases structurally related to acetylcholinesterase. Chemical Research in Toxicology. 14: 807-13. PMID 11453726 DOI: 10.1021/Tx015501S  0.507
2000 Doorn JA, Gage DA, Schall M, Talley TT, Thompson CM, Richardson RJ. Inhibition of acetylcholinesterase by (1S,3S)-isomalathion proceeds with loss of thiomethyl: kinetic and mass spectral evidence for an unexpected primary leaving group. Chemical Research in Toxicology. 13: 1313-20. PMID 11123973 DOI: 10.1021/Tx000184V  0.494
1999 Jianmongkol S, Marable BR, Berkman CE, Talley TT, Thompson CM, Richardson RJ. Kinetic evidence for different mechanisms of acetylcholinesterase inhibition by (1R)- and (1S)-stereoisomers of isomalathion. Toxicology and Applied Pharmacology. 155: 43-53. PMID 10036217 DOI: 10.1006/Taap.1998.8608  0.49
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