Year |
Citation |
Score |
2024 |
Schofield JH, Longo J, Sheldon RD, Albano E, Ellis AE, Hawk MA, Murphy S, Duong L, Rahmy S, Lu X, Jones RG, Schafer ZT. Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides. Cell Reports. 43: 113984. PMID 38520689 DOI: 10.1016/j.celrep.2024.113984 |
0.346 |
|
2023 |
Rodencal J, Kim N, He A, Li VL, Lange M, He J, Tarangelo A, Schafer ZT, Olzmann JA, Long JZ, Sage J, Dixon SJ. Sensitization of cancer cells to ferroptosis coincident with cell cycle arrest. Cell Chemical Biology. PMID 37963466 DOI: 10.1016/j.chembiol.2023.10.011 |
0.385 |
|
2023 |
Schofield JH, Longo J, Sheldon RD, Albano E, Hawk MA, Murphy S, Duong L, Rahmy S, Lu X, Jones RG, Schafer ZT. Acod1 Expression in Cancer Cells Promotes Immune Evasion through the Generation of Inhibitory Peptides. Biorxiv : the Preprint Server For Biology. PMID 37745450 DOI: 10.1101/2023.09.14.557799 |
0.323 |
|
2023 |
Schofield JH, Schafer ZT. Regulators mount up: the metabolic roles of apoptotic proteins. Frontiers in Cell Death. 2. PMID 37521407 DOI: 10.3389/fceld.2023.1223926 |
0.353 |
|
2023 |
Rodencal J, Kim N, Li VL, He A, Lange M, He J, Tarangelo A, Schafer ZT, Olzmann JA, Sage J, Long JZ, Dixon SJ. A Cell Cycle-Dependent Ferroptosis Sensitivity Switch Governed by EMP2. Biorxiv : the Preprint Server For Biology. PMID 37502927 DOI: 10.1101/2023.07.19.549715 |
0.355 |
|
2023 |
Hom LM, Sun S, Campbell J, Liu P, Culbert S, Murphy IM, Schafer ZT. A role for fibroblast-derived SASP factors in the activation of pyroptotic cell death in mammary epithelial cells. The Journal of Biological Chemistry. 104922. PMID 37321449 DOI: 10.1016/j.jbc.2023.104922 |
0.448 |
|
2023 |
He J, Abikoye AM, McLaughlin BP, Middleton RS, Sheldon R, Jones RG, Schafer ZT. Reprogramming of iron metabolism confers ferroptosis resistance in ECM-detached cells. Iscience. 26: 106827. PMID 37250802 DOI: 10.1016/j.isci.2023.106827 |
0.34 |
|
2023 |
Hom LM, Sun S, Campbell J, Liu P, Culbert S, Murphy IM, Schafer ZT. A role for fibroblast-derived SASP factors in the activation of pyroptotic cell death in mammary epithelial cells. Biorxiv : the Preprint Server For Biology. PMID 36865231 DOI: 10.1101/2023.02.21.529458 |
0.448 |
|
2021 |
Cockfield JA, Schafer ZT. SGK1-regulated metabolism: key for the survival of cells detached from the extracellular matrix. Molecular & Cellular Oncology. 8: 1976583. PMID 34859141 DOI: 10.1080/23723556.2021.1976583 |
0.347 |
|
2021 |
Tsegaye MA, He J, McGeehan K, Murphy IM, Nemera M, Schafer ZT. Oncogenic signaling inhibits c-FLIP expression and its non-apoptotic function during ECM-detachment. Scientific Reports. 11: 18606. PMID 34545139 DOI: 10.1038/s41598-021-97715-4 |
0.492 |
|
2021 |
Mason JA, Cockfield JA, Pape DJ, Meissner H, Sokolowski MT, White TC, Valentín López JC, Liu J, Liu X, Martínez-Reyes I, Chandel NS, Locasale JW, Schafer ZT. SGK1 signaling promotes glucose metabolism and survival in extracellular matrix detached cells. Cell Reports. 34: 108821. PMID 33730592 DOI: 10.1016/j.celrep.2021.108821 |
0.386 |
|
2021 |
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Schafer ZT, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280 |
0.624 |
|
2020 |
Luo Y, Medina Bengtsson L, Wang X, Huang T, Liu G, Murphy S, Wang C, Koren J, Schafer Z, Lu X. UQCRH downregulation promotes Warburg effect in renal cell carcinoma cells. Scientific Reports. 10: 15021. PMID 32929120 DOI: 10.1038/S41598-020-72107-2 |
0.498 |
|
2020 |
Schofield JH, Schafer ZT. Mitochondrial ROS and Mitophagy: A Complex and Nuanced Relationship. Antioxidants & Redox Signaling. PMID 32079408 DOI: 10.1089/Ars.2020.8058 |
0.366 |
|
2020 |
Tsegaye MA, McGeehan K, Nemera M, Schafer ZT. Abstract 1444: c-FLIP antagonizes the survival of extracellular matrix detached cancer cells Immunology. DOI: 10.1158/1538-7445.Am2020-1444 |
0.471 |
|
2019 |
Cockfield JA, Schafer ZT. Antioxidant Defenses: A Context-Specific Vulnerability of Cancer Cells. Cancers. 11. PMID 31434226 DOI: 10.3390/Cancers11081208 |
0.458 |
|
2018 |
Hawk MA, Schafer ZT. RIPK1-dependent mitophagy: A novel mechanism to eliminate cells detached from the extracellular matrix. Molecular & Cellular Oncology. 5: e1465015. PMID 30250916 DOI: 10.1080/23723556.2018.1465015 |
0.536 |
|
2018 |
Hawk MA, Gorsuch CL, Fagan P, Lee C, Kim SE, Hamann JC, Mason JA, Weigel KJ, Tsegaye MA, Shen L, Shuff S, Zuo J, Hu S, Jiang L, Chapman S, ... ... Schafer ZT, et al. RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells. Nature Cell Biology. PMID 29459781 DOI: 10.1038/S41556-018-0034-2 |
0.583 |
|
2018 |
Hawk MA, Schafer ZT. Mechanisms of redox metabolism and cancer cell survival during extracellular matrix detachment. The Journal of Biological Chemistry. PMID 29339552 DOI: 10.1074/Jbc.Tm117.000260 |
0.527 |
|
2018 |
Hawk MA, Schafer ZT. Abstract 2410: RIPK1-mediated induction of mitophagy compromises the viability of extracellular matrix-detached cells Cancer Research. 78: 2410-2410. DOI: 10.1158/1538-7445.Am2018-2410 |
0.581 |
|
2017 |
Tsegaye MA, Schafer ZT. Collapsing the Metabolic PON2zi Scheme in Pancreatic Ductal Adenocarcinoma. Trends in Cell Biology. PMID 28988620 DOI: 10.1016/J.Tcb.2017.09.003 |
0.389 |
|
2017 |
Mason JA, Hagel KR, Hawk MA, Schafer ZT. Metabolism during ECM Detachment: Achilles Heel of Cancer Cells? Trends in Cancer. 3: 475-481. PMID 28718402 DOI: 10.1016/J.Trecan.2017.04.009 |
0.527 |
|
2017 |
Mason JA, Schafer ZT. Ras-ling with new therapeutic targets for metastasis. Small Gtpases. 1-5. PMID 28471257 DOI: 10.1080/21541248.2017.1310650 |
0.427 |
|
2017 |
Masoud ZS, Kim L, Weigel KJ, Champion MM, Schafer ZT, Leung C. Abstract 1996: CXCL12 drives selective expansion of AKT-induced quiescent, pre-neoplastic breast cells Cancer Research. 77: 1996-1996. DOI: 10.1158/1538-7445.Am2017-1996 |
0.411 |
|
2016 |
Hawk MA, McCallister C, Schafer ZT. Antioxidant Activity during Tumor Progression: A Necessity for the Survival of Cancer Cells? Cancers. 8. PMID 27754368 DOI: 10.3390/Cancers8100092 |
0.405 |
|
2016 |
Buchheit CL, Schafer ZT. BIM-EL localization: The key to understanding anoikis resistance in inflammatory breast cancer cells. Molecular & Cellular Oncology. 3: e1011474. PMID 27308529 DOI: 10.1080/23723556.2015.1011474 |
0.396 |
|
2016 |
Mason JA, Davison-Versagli CA, Leliaert AK, Pape DJ, McCallister C, Zuo J, Durbin SM, Buchheit CL, Zhang S, Schafer ZT. Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells. Cell Death and Differentiation. PMID 26915296 DOI: 10.1038/Cdd.2016.15 |
0.497 |
|
2016 |
Hagel K, Weigel K, Boyd M, McCormack L, Champion M, Schafer Z. Abstract 4087: Mammary fibroblasts exert divergent effects on the survival of invasive breast cancer cells Cancer Research. 76: 4087-4087. DOI: 10.1158/1538-7445.Am2016-4087 |
0.419 |
|
2016 |
McCallister CM, Rayavarapu R, Pagani N, Heiden B, Shaw M, Shuff S, Schafer ZT. Abstract 3563: Ras-mediated regulation of cytochrome c-induced caspase activation is dependent on the status of extracellular matrix attachment Cancer Research. 76: 3563-3563. DOI: 10.1158/1538-7445.Am2016-3563 |
0.505 |
|
2016 |
Hawk MA, Buchheit CL, Shen L, Fagan P, Schafer ZT. Abstract 3550: Activation of a novel form of regulated necrosis to eliminate extracellular matrix detached epithelial cells Cancer Research. 76: 3550-3550. DOI: 10.1158/1538-7445.Am2016-3550 |
0.582 |
|
2016 |
Shen L, Weigel K, Thomas C, Drapalik L, Schafer ZT, Lee S. Abstract 347: Developing a novel immunotoxin that targets cells overexpressing ErbB2 Cancer Research. 76: 347-347. DOI: 10.1158/1538-7445.Am2016-347 |
0.473 |
|
2015 |
Weigel KJ, Shen L, Thomas CL, Alber D, Drapalik L, Schafer ZT, Lee SW. Design and evaluation of a peptide-based immunotoxin for breast cancer therapeutics. Febs Open Bio. 5: 202-8. PMID 25853036 DOI: 10.1016/J.Fob.2015.03.005 |
0.413 |
|
2015 |
Rayavarapu RR, Heiden B, Pagani N, Shaw MM, Shuff S, Zhang S, Schafer ZT. The role of multicellular aggregation in the survival of ErbB2-positive breast cancer cells during extracellular matrix detachment. The Journal of Biological Chemistry. 290: 8722-33. PMID 25681438 DOI: 10.1074/Jbc.M114.612754 |
0.539 |
|
2015 |
Buchheit CL, Angarola BL, Steiner A, Weigel KJ, Schafer ZT. Anoikis evasion in inflammatory breast cancer cells is mediated by Bim-EL sequestration. Cell Death and Differentiation. 22: 1275-86. PMID 25526094 DOI: 10.1038/Cdd.2014.209 |
0.574 |
|
2015 |
Mason JA, Versagli C, Leliaert A, Durbin S, Buchheit C, Schafer Z. Abstract 2148: Ras-mediated evasion of detachment-induced cell death involves differential signaling pathways for metabolism and anoikis Cancer Research. 75: 2148-2148. DOI: 10.1158/1538-7445.Am2015-2148 |
0.473 |
|
2015 |
Buchheit C, Angarola B, Steiner A, Weigel K, Schafer Z. Abstract 1268: Anoikis evasion in inflammatory breast cancer cells is mediated by Bim-EL sequestration Cancer Research. 75: 1268-1268. DOI: 10.1158/1538-7445.Am2015-1268 |
0.589 |
|
2015 |
Durbin SM, Versagli C, Pape D, Schafer Z. Abstract 1144: Antioxidant enzyme-mediated survival of ECM-detached breast cancer cells requires AMPK activation Cancer Research. 75: 1144-1144. DOI: 10.1158/1538-7445.Am2015-1144 |
0.435 |
|
2014 |
Buchheit CL, Weigel KJ, Schafer ZT. Cancer cell survival during detachment from the ECM: multiple barriers to tumour progression. Nature Reviews. Cancer. 14: 632-41. PMID 25098270 DOI: 10.1038/Nrc3789 |
0.483 |
|
2014 |
Weigel KJ, Jakimenko A, Conti BA, Chapman SE, Kaliney WJ, Leevy WM, Champion MM, Schafer ZT. CAF-secreted IGFBPs regulate breast cancer cell anoikis. Molecular Cancer Research : McR. 12: 855-66. PMID 24803643 DOI: 10.1158/1541-7786.Mcr-14-0090 |
0.52 |
|
2014 |
Schafer ZT. Abstract 3587: Carcinoma-associated fibroblast-mediated regulation of anoikis in breast cancer cells Cancer Research. 74: 3587-3587. DOI: 10.1158/1538-7445.Am2014-3587 |
0.538 |
|
2014 |
Rayavarapu R, Pagani N, Heiden B, Schafer ZT. Abstract 1347: The role of cell-cell contacts in the survival of extracellular matrix detached mammary epithelial cells Cancer Research. 74: 1347-1347. DOI: 10.1158/1538-7445.Am2014-1347 |
0.519 |
|
2013 |
Davison CA, Durbin SM, Thau MR, Zellmer VR, Chapman SE, Diener J, Wathen C, Leevy WM, Schafer ZT. Antioxidant enzymes mediate survival of breast cancer cells deprived of extracellular matrix. Cancer Research. 73: 3704-15. PMID 23771908 DOI: 10.1158/0008-5472.Can-12-2482 |
0.525 |
|
2013 |
Weigel K, Jakimenko A, Conti B, Kaliney W, Champion MM, Schafer ZT. Abstract 1634: The regulation of anoikis by carcinoma-associated fibroblasts in breast cancer cells. Cancer Research. 73: 1634-1634. DOI: 10.1158/1538-7445.Am2013-1634 |
0.538 |
|
2012 |
Ito K, Carracedo A, Weiss D, Arai F, Ala U, Avigan DE, Schafer ZT, Evans RM, Suda T, Lee CH, Pandolfi PP. A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nature Medicine. 18: 1350-8. PMID 22902876 DOI: 10.1038/Nm.2882 |
0.417 |
|
2012 |
Carracedo A, Weiss D, Leliaert AK, Bhasin M, de Boer VC, Laurent G, Adams AC, Sundvall M, Song SJ, Ito K, Finley LS, Egia A, Libermann T, Gerhart-Hines Z, Puigserver P, ... ... Schafer ZT, et al. A metabolic prosurvival role for PML in breast cancer. The Journal of Clinical Investigation. 122: 3088-100. PMID 22886304 DOI: 10.1172/Jci62129 |
0.419 |
|
2012 |
Schafer ZT, Nutt LK. Understanding tumor cell metabolism: the secret to winning the war (burg) on cancer? Seminars in Cell & Developmental Biology. 23: 351. PMID 22580192 DOI: 10.1016/J.Semcdb.2012.04.008 |
0.39 |
|
2012 |
Buchheit CL, Rayavarapu RR, Schafer ZT. The regulation of cancer cell death and metabolism by extracellular matrix attachment. Seminars in Cell & Developmental Biology. 23: 402-11. PMID 22579674 DOI: 10.1016/J.Semcdb.2012.04.007 |
0.533 |
|
2012 |
Ito K, Carracedo A, Arai F, Ala U, Avigan D, Schafer Z, Evans RM, Suda T, Lee C, Pandolfi PP. A PML–PPAR-δ Pathway for Fatty Acid Oxidation Regulates Hematopoietic Stem Cell Maintenance Through the Control of Asymmetric Division. Blood. 120: 2327-2327. DOI: 10.1182/Blood.V120.21.2327.2327 |
0.397 |
|
2012 |
Jakimenko A, Weigel K, Hyatt R, Kaliney W, Champion M, Schafer ZT. Abstract 2083: The regulation of anoikis by carcinoma-associated fibroblasts in breast cancer cells Cancer Research. 72: 2083-2083. DOI: 10.1158/1538-7445.Am2012-2083 |
0.531 |
|
2012 |
Rayavarapu R, Schafer Z. Abstract 2082: The role of cell-cell contacts in the survival of extracellular matrix detached mammary epithelial cells Cancer Research. 72: 2082-2082. DOI: 10.1158/1538-7445.Am2012-2082 |
0.522 |
|
2012 |
Buchheit CL, Angarola B, Steiner A, Schafer Z. Abstract 2080: The role of ErbB2 in regulating survival in matrix-detached inflammatory breast cancer cells Cancer Research. 72: 2080-2080. DOI: 10.1158/1538-7445.Am2012-2080 |
0.565 |
|
2011 |
Grassian AR, Schafer ZT, Brugge JS. ErbB2 stabilizes epidermal growth factor receptor (EGFR) expression via Erk and Sprouty2 in extracellular matrix-detached cells. The Journal of Biological Chemistry. 286: 79-90. PMID 20956544 DOI: 10.1074/Jbc.M110.169821 |
0.729 |
|
2011 |
Young J, Leliaert A, Schafer ZT, Taylor RE. Abstract C67: Gene expression profiling with human breast cancer cell lines exposed to gephyronic acid Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-C67 |
0.383 |
|
2011 |
Angarola BL, Schafer ZT. Abstract 418: Cellular mechanisms underlying the evasion of detachment-induced cell death in inflammatory breast cancer cells Cancer Research. 71: 418-418. DOI: 10.1158/1538-7445.Am2011-418 |
0.594 |
|
2011 |
Schafer ZT. Abstract 1270: Metabolic alterations impair breast cancer cell viability following detachment from the extracellular matrix Cancer Research. 71: 1270-1270. DOI: 10.1158/1538-7445.Am2011-1270 |
0.584 |
|
2011 |
Leliaert AK, Schafer ZT. Abstract 1238: The role of Ras-mediated SGK-1 Signaling in the Survival of ECM-detached mammary epithelial cells Cancer Research. 71: 1238-1238. DOI: 10.1158/1538-7445.Am2011-1238 |
0.448 |
|
2010 |
Davison CA, Schafer ZT. Keeping a breast of recent developments in cancer metabolism. Current Drug Targets. 11: 1112-20. PMID 20545609 DOI: 10.2174/138945010792006861 |
0.439 |
|
2009 |
Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver P, Brugge JS. Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment. Nature. 461: 109-13. PMID 19693011 DOI: 10.1038/Nature08268 |
0.753 |
|
2009 |
Schafer Z, Grassian A, Song L, Mailleux A, Schmelzle T, Irie Y, Gao G, Overholtzer M, Jiang Z, Gerhart‐Hines Z, Puigsever P, Brugge JS. Abstract IA-13: Mechanisms regulating anchorage independent survival Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-Ia-13 |
0.653 |
|
2007 |
Schafer ZT, Brugge JS. IL-6 involvement in epithelial cancers. The Journal of Clinical Investigation. 117: 3660-3. PMID 18060028 DOI: 10.1172/Jci34237 |
0.5 |
|
2006 |
Schafer ZT, Kornbluth S. The apoptosome: physiological, developmental, and pathological modes of regulation. Developmental Cell. 10: 549-61. PMID 16678772 DOI: 10.1016/J.Devcel.2006.04.008 |
0.664 |
|
2006 |
Schafer ZT, Parrish AB, Wright KM, Margolis SS, Marks JR, Deshmukh M, Kornbluth S. Enhanced sensitivity to cytochrome c-induced apoptosis mediated by PHAPI in breast cancer cells. Cancer Research. 66: 2210-8. PMID 16489023 DOI: 10.1158/0008-5472.Can-05-3923 |
0.767 |
|
2004 |
Deming PB, Schafer ZT, Tashker JS, Potts MB, Deshmukh M, Kornbluth S. Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release. Molecular and Cellular Biology. 24: 10289-99. PMID 15542838 DOI: 10.1128/Mcb.24.23.10289-10299.2004 |
0.638 |
|
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