Year |
Citation |
Score |
2009 |
MartÃnez MC, Fernandez SP, Loscalzo LM, Wasowski C, Paladini AC, Marder M, Medina JH, Viola H. Hesperidin, a flavonoid glycoside with sedative effect, decreases brain pERK1/2 levels in mice. Pharmacology, Biochemistry, and Behavior. 92: 291-6. PMID 19159642 DOI: 10.1016/J.Pbb.2008.12.016 |
0.425 |
|
2003 |
Marder M, Viola H, Wasowski C, Fernández S, Medina JH, Paladini AC. 6-methylapigenin and hesperidin: new valeriana flavonoids with activity on the CNS. Pharmacology, Biochemistry, and Behavior. 75: 537-45. PMID 12895671 DOI: 10.1016/S0091-3057(03)00121-7 |
0.451 |
|
2002 |
Wasowski C, Marder M, Viola H, Medina JH, Paladini AC. Isolation and identification of 6-methylapigenin, a competitive ligand for the brain GABA(A) receptors, from Valeriana wallichii. Planta Medica. 68: 934-6. PMID 12391561 DOI: 10.1055/S-2002-34936 |
0.509 |
|
2001 |
Marder M, Estiú G, Blanch LB, Viola H, Wasowski C, Medina JH, Paladini AC. Molecular modeling and QSAR analysis of the interaction of flavone derivatives with the benzodiazepine binding site of the GABA(A) receptor complex. Bioorganic & Medicinal Chemistry. 9: 323-35. PMID 11249125 DOI: 10.1016/S0968-0896(00)00250-9 |
0.535 |
|
2000 |
Viola H, Marder M, Wasowski C, Giorgi O, Paladini AC, Medina JH. 6,3'-dibromoflavone and 6-nitro-3'-bromoflavone: new additions to the 6,3'-disubstituted flavone family of high-affinity ligands of the brain benzodiazepine binding site with agonistic properties. Biochemical and Biophysical Research Communications. 273: 694-8. PMID 10873666 DOI: 10.1006/Bbrc.2000.2979 |
0.53 |
|
2000 |
Viola H, Wolfman C, Marder M, Goutman JD, Bianchin M, Wasowski C, Calvo DJ, Izquierdo I, Paladini AC, Medina JH. 6-Chloro-3'-nitroflavone is a potent ligand for the benzodiazepine binding site of the GABA(A) receptor devoid of intrinsic activity. Pharmacology, Biochemistry, and Behavior. 65: 313-20. PMID 10672984 DOI: 10.1016/S0091-3057(99)00199-9 |
0.501 |
|
1999 |
Viola H, Marder M, Nuñez J, Izquierdo L, Wasowski C, Wolfman C, Ardenghi P, Barros D, Medina JH, Paladini AC. 6-Methyl-3'-bromoflavone, a high-affinity ligand for the benzodiazepine binding site of the GABA(A) receptor with some antagonistic properties. Biochemical and Biophysical Research Communications. 262: 643-6. PMID 10471378 DOI: 10.1006/bbrc.1999.1273 |
0.504 |
|
1999 |
Paladini AC, Marder M, Viola H, Wolfman C, Wasowski C, Medina JH. Flavonoids and the central nervous system: from forgotten factors to potent anxiolytic compounds. The Journal of Pharmacy and Pharmacology. 51: 519-26. PMID 10411210 DOI: 10.1211/0022357991772790 |
0.51 |
|
1998 |
Medina JH, Viola H, Wolfman C, Marder M, Wasowski C, Calvo D, Paladini AC. Neuroactive flavonoids: new ligands for the Benzodiazepine receptors. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 5: 235-43. PMID 23195847 DOI: 10.1016/S0944-7113(98)80034-2 |
0.524 |
|
1998 |
Wolfman C, Viola H, Marder M, Ardenghi P, Wasowski C, Schröder N, Izquierdo I, Rúveda E, Paladini A, Medina JH. Pharmacological characterization of 6-bromo-3'-nitroflavone, a synthetic flavonoid with high affinity for the benzodiazepine receptors. Pharmacology, Biochemistry, and Behavior. 61: 239-46. PMID 9768558 DOI: 10.1016/S0091-3057(98)00088-4 |
0.555 |
|
1998 |
Marder M, Viola H, Bacigaluppo JA, Colombo MI, Wasowski C, Wolfman C, Medina JH, Rúveda EA, Paladini AC. Detection of benzodiazepine receptor ligands in small libraries of flavone derivatives synthesized by solution phase combinatorial chemistry. Biochemical and Biophysical Research Communications. 249: 481-5. PMID 9712722 DOI: 10.1006/Bbrc.1998.9146 |
0.511 |
|
1998 |
Viola H, Marder M, Wolfman C, Wasowski C, Medina JH, Paladini AC. Central nervous system effects of natural and synthetic flavonoids Anales Des La Asociacion Quimica Argentina. 86: 229-236. |
0.421 |
|
1997 |
Viola H, Wasowski C, Marder M, Wolfman C, Paladini AC, Medina JH. Sedative and hypnotic properties of Salvia guaranitica St. Hil. and of its active principle, Cirsiliol. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 4: 47-52. PMID 23195245 DOI: 10.1016/S0944-7113(97)80027-X |
0.511 |
|
1997 |
Medina JH, Viola H, Wolfman C, Marder M, Wasowski C, Calvo D, Paladini AC. Overview--flavonoids: a new family of benzodiazepine receptor ligands. Neurochemical Research. 22: 419-25. PMID 9130252 DOI: 10.1023/A:1027303609517 |
0.506 |
|
1997 |
Marder M, Zinczuk J, Colombo MI, Wasowski C, Viola H, Wolfman C, Medina JH, Rúveda EA, Paladini AC. Synthesis of halogenated/nitrated flavone derivatives and evaluation of their affinity for the central benzodiazepine receptor Bioorganic and Medicinal Chemistry Letters. 7: 2003-2008. DOI: 10.1016/S0960-894X(97)00343-0 |
0.507 |
|
1997 |
Viola H, Marder M, Wolfman C, Wasowski C, Medina JH, Paladini AC. 6-Bromo-3'-nitroflavone, a new high affinity benzodiazepine receptor agonist recognizes two populations of cerebral cortical binding sites Bioorganic and Medicinal Chemistry Letters. 7: 373-378. DOI: 10.1016/S0960-894X(97)00020-6 |
0.496 |
|
1996 |
Marder M, Viola H, Wasowski C, Wolfman C, Waterman PG, Medina JH, Paladini AC. Cirsiliol and caffeic acid ethyl ester, isolated from Salvia guaranitica, are competitive ligands for the central benzodiazepine receptors. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 3: 29-31. PMID 23194857 DOI: 10.1016/S0944-7113(96)80006-7 |
0.509 |
|
1996 |
Wolfman C, Viola H, Marder M, Wasowski C, Ardenghi P, Izquierdo I, Paladini AC, Medina JH. Anxioselective properties of 6,3'-dinitroflavone, a high-affinity benzodiazepine receptor ligand. European Journal of Pharmacology. 318: 23-30. PMID 9007508 DOI: 10.1016/S0014-2999(96)00784-4 |
0.531 |
|
1995 |
Viola H, Wasowski C, Levi de Stein M, Wolfman C, Silveira R, Dajas F, Medina JH, Paladini AC. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Medica. 61: 213-6. PMID 7617761 DOI: 10.1055/s-2006-958058 |
0.551 |
|
1995 |
Marder M, Viola H, Wasowski C, Wolfman C, Waterman PG, Medina JH, Paladini AC. 6,3'-Dinitroflavone, a novel high affinity ligand for the benzodiazepine receptor with potent anxiolytic properties Bioorganic and Medicinal Chemistry Letters. 5: 2717-2720. DOI: 10.1016/0960-894X(95)00464-5 |
0.522 |
|
1994 |
Viola H, Wolfman C, Levi de Stein M, Wasowski C, Peña C, Medina JH, Paladini AC. Isolation of pharmacologically active benzodiazepine receptor ligands from Tilia tomentosa (Tiliaceae). Journal of Ethnopharmacology. 44: 47-53. PMID 7990504 DOI: 10.1016/0378-8741(94)90098-1 |
0.532 |
|
1994 |
Wolfman C, Viola H, Paladini A, Dajas F, Medina JH. Possible anxiolytic effects of chrysin, a central benzodiazepine receptor ligand isolated from Passiflora coerulea. Pharmacology, Biochemistry, and Behavior. 47: 1-4. PMID 7906886 DOI: 10.1016/0091-3057(94)90103-1 |
0.542 |
|
1993 |
Medina JH, Levi de Stein M, Wolfman C, Wasowski C, De Blas A, Paladini AC. In vivo formation of benzodiazepine-like molecules in mammalian brain. Biochemical and Biophysical Research Communications. 195: 1111-8. PMID 8396918 DOI: 10.1006/Bbrc.1993.2159 |
0.48 |
|
1993 |
Medina JH, Paladini AC, Izquierdo I. Naturally occurring benzodiazepines and benzodiazepine-like molecules in brain. Behavioural Brain Research. 58: 1-8. PMID 8136037 DOI: 10.1016/0166-4328(93)90085-5 |
0.446 |
|
1992 |
Medina JH, Peña C, Piva M, Wolfman C, de Stein ML, Wasowski C, Da Cunha C, Izquierdo I, Paladini AC. Benzodiazepines in the brain. Their origin and possible biological roles. Molecular Neurobiology. 6: 377-86. PMID 1337455 DOI: 10.1007/Bf02757942 |
0.442 |
|
1991 |
Peña C, Medina JH, Piva M, Diaz LE, Danilowicz C, Paladini AC. Naturally occurring benzodiazepines in human milk. Biochemical and Biophysical Research Communications. 175: 1042-50. PMID 2025236 DOI: 10.1016/0006-291X(91)91670-8 |
0.417 |
|
1991 |
Medina JH, Danelon JL, Wasowski C, Levi de Stein M, Paladini AC. Production of benzodiazepine-like compounds in bovine rumen. Biochemical and Biophysical Research Communications. 181: 1048-55. PMID 1764056 DOI: 10.1016/0006-291X(91)92043-J |
0.437 |
|
1990 |
Medina JH, Paladini AC, Wolfman C, Levi de Stein M, Calvo D, Diaz LE, Peña C. Chrysin (5,7-di-OH-flavone), a naturally-occurring ligand for benzodiazepine receptors, with anticonvulsant properties. Biochemical Pharmacology. 40: 2227-31. PMID 2173925 DOI: 10.1016/0006-2952(90)90716-X |
0.52 |
|
1990 |
Medina J, Peña C, Piva M, Rubio M, Wikinski S, Paladini A. Benzodiazepine-like molecules in human milk. Lancet (London, England). 336: 1379. PMID 1978183 DOI: 10.1016/0140-6736(90)92931-7 |
0.471 |
|
1989 |
Medina JH, Peña C, Levi de Stein M, Wolfman C, Paladini AC. Benzodiazepine-like molecules, as well as other ligands for the brain benzodiazepine receptors, are relatively common constituents of plants. Biochemical and Biophysical Research Communications. 165: 547-53. PMID 2557016 DOI: 10.1016/S0006-291X(89)80001-4 |
0.493 |
|
1988 |
Robertis ED, Peña C, Paladini AC, Medina JH. New developments on the search for the endogenous ligand(s) of central benzodiazepine receptors. Neurochemistry International. 13: 1-11. PMID 20501264 DOI: 10.1016/0197-0186(88)90095-2 |
0.529 |
|
1988 |
Medina JH, Peña C, Piva M, Paladini AC, De Robertis E. Presence of benzodiazepine-like molecules in mammalian brain and milk. Biochemical and Biophysical Research Communications. 152: 534-9. PMID 3365238 DOI: 10.1016/S0006-291X(88)80070-6 |
0.466 |
|
1988 |
Peña C, Medina JH, Novas ML, De Robertis E, Paladini AC. Determination of n-butyl-beta-carboline-3-carboxylate in aqueous brain extracts. Journal of Chromatography. 431: 192-6. PMID 3235530 DOI: 10.1016/S0378-4347(00)83084-4 |
0.407 |
|
1987 |
Medina JH, Peña C, Novas ML, Paladini AC, De Robertis E. Acute stress induces an increase in rat cerebral cortex levels of n-butyl-?-carboline-3-carboxylate, an endogenous benzodiazepine binding inhibitor. Neurochemistry International. 11: 255-9. PMID 20501168 DOI: 10.1016/0197-0186(87)90043-X |
0.457 |
|
1986 |
Peña C, Medina JH, Novas ML, Paladini AC, De Robertis E. Isolation and identification in bovine cerebral cortex of n-butyl beta-carboline-3-carboxylate, a potent benzodiazepine binding inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 83: 4952-6. PMID 3014522 DOI: 10.1073/Pnas.83.13.4952 |
0.449 |
|
1983 |
Bonifacino JS, Roguin LP, Paladini AC. Formation of complexes between 125I-labelled human or bovine somatotropins and binding proteins in vivo in rat liver and kidney. The Biochemical Journal. 214: 121-32. PMID 6615460 DOI: 10.1042/Bj2140121 |
0.455 |
|
1982 |
Roguin LP, Sánchez SH, Bonifacino JS, Paladini AC. Human somatotropin binding to rabbit kidney microsomal fraction. The Biochemical Journal. 200: 257-64. PMID 7340833 DOI: 10.1042/Bj2000257 |
0.484 |
|
1982 |
Roguin LP, Bonifacino JS, Paladini AC. Properties of human growth hormone binding sites solubilized from female rabbit kidney. Biochimica Et Biophysica Acta. 715: 222-9. PMID 7074140 DOI: 10.1016/0304-4165(82)90362-2 |
0.473 |
|
1982 |
Bonifacino JS, Paladini AC. Effect of the incomplete separation of bound and free ligand on binding measurements. Analytical Biochemistry. 118: 213-20. PMID 6278982 DOI: 10.1016/0003-2697(81)90181-0 |
0.486 |
|
1982 |
Bonifacino JS, Sánchez SH, Paladini AC. Characterization of human somatotropin binding to detergent-solubilized lactogenic receptors from rat liver. The Biochemical Journal. 194: 385-94. PMID 6272729 DOI: 10.1042/Bj1940385 |
0.522 |
|
1979 |
Bonifacino JS, Sánchez SH, Paladini AC. Solubilization of the lactogenic receptors from rat liver microsomes. Biochemical and Biophysical Research Communications. 85: 62-9. PMID 217383 DOI: 10.1016/S0006-291X(78)80011-4 |
0.508 |
|
1964 |
CRAIG LC, HARFENIST EJ, PALADINI AC. DIALYSIS STUDIES. 7. THE BEHAVIOR OF ANGIOTENSIN, OXYTOCIN, VASOPRESSIN, AND SOME OF THEIR ANALOGS. Biochemistry. 3: 764-9. PMID 14211612 DOI: 10.1021/Bi00894A005 |
0.435 |
|
1957 |
Leloir LF, Paladini AC. [143] Preparation and assay of UDPG and related compounds Methods in Enzymology. 3: 968-974. DOI: 10.1016/S0076-6879(57)03487-4 |
0.519 |
|
1957 |
Leloir LF, Paladini AC. [17] Isolation of glucose-1,6-diphosphate Methods in Enzymology. 3: 143-147. DOI: 10.1016/S0076-6879(57)03356-X |
0.533 |
|
1954 |
Paladini A, Craig LC. The Chemistry of Tyrocidine. III. The Structure of Tyrocidine A Journal of the American Chemical Society. 76: 688-692. DOI: 10.1021/Ja01632A015 |
0.425 |
|
1952 |
PALADINI AC, LELOIR LF. Studies on uridine-diphosphate-glucose. The Biochemical Journal. 51: 426-30. PMID 12977745 DOI: 10.1042/Bj0510426 |
0.506 |
|
1952 |
Paladini AC, Leloir LF. Detection of ultraviolet-absorbing substances on paper chromatograms Analytical Chemistry. 24: 1024-1025. |
0.48 |
|
1950 |
CAPUTTO R, LELOIR LF, CARDINI CE, PALADINI AC. Isolation of the coenzyme of the galactose phosphate-glucose phosphate transformation. The Journal of Biological Chemistry. 184: 333-50. PMID 15422002 |
0.514 |
|
1950 |
CARDINI CE, PALADINI AC, CAPUTTO R, LELOIR LF. Liver uridine phosphorylase. Acta Physiologica Latino Americana. 1: 57-63. PMID 14799260 |
0.481 |
|
1950 |
Cardini CE, Paladini AC, Caputto R, Leloir LF. Uridine diphosphate glucose: The coenzyme of the galactose-glucose phosphate isomerization Nature. 165: 191-192. DOI: 10.1038/165191A0 |
0.511 |
|
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