Manuela Garcia Lopez - Publications

Affiliations: 
Pharmacology Universidad Autónoma de Madrid, Madrid, Comunidad de Madrid, Spain 
Area:
neuroprotection

207 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Casas AI, Kleikers PW, Geuss E, Langhauser F, Adler T, Busch DH, Gailus-Durner V, de Angelis MH, Egea J, Lopez MG, Kleinschnitz C, Schmidt HH. Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke. The Journal of Clinical Investigation. 130. PMID 30882367 DOI: 10.1172/JCI124283  0.84
2017 Casas AI, Geuss E, Kleikers PWM, Mencl S, Herrmann AM, Buendia I, Egea J, Meuth SG, Lopez MG, Kleinschnitz C, Schmidt HHHW. NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage. Proceedings of the National Academy of Sciences of the United States of America. PMID 29087944 DOI: 10.1073/pnas.1705034114  0.84
2017 Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, et al. European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biology. 13: 94-162. PMID 28577489 DOI: 10.1016/j.redox.2017.05.007  0.84
2016 Navarro E, Gonzalez-Lafuente L, Perez-Liebana I, Buendia I, López-Bernardo E, Sanchez-Ramos C, Prieto I, Cuadrado A, Satrustegui J, Cadenas S, Monsalve M, Lopez MG. Heme-oxygenase I and PCG-1α regulate mitochondrial biogenesis via microglial activation of alpha7 nicotinic acetylcholine receptors using PNU282987. Antioxidants & Redox Signaling. PMID 27554853 DOI: 10.1089/ars.2016.6698  0.84
2015 Wojnicz A, Ortiz JA, Casas AI, Freitas AE, López MG, Ruiz-Nuño A. Simultaneous determination of 8 neurotransmitters and their metabolite levels in rat brain using liquid chromatography in tandem with mass spectrometry: Application to the murine Nrf2 model of depression. Clinica Chimica Acta; International Journal of Clinical Chemistry. PMID 26712273 DOI: 10.1016/j.cca.2015.12.023  0.6
2015 Zha X, Lamba D, Zhang L, Lou Y, Xu C, Kang D, Chen L, Xu Y, Zhang L, De Simone A, Samez S, Pesaresi A, Stojan J, López MG, Egea J, et al. Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation and X-ray Crystallography. Journal of Medicinal Chemistry. PMID 26632651 DOI: 10.1021/acs.jmedchem.5b01119  0.84
2015 Casas AI, Dao VT, Daiber A, Maghzal GJ, Di Lisa F, Kaludercic N, Leach S, Cuadrado A, Jaquet V, Seredenina T, Krause KH, López MG, Stocker R, Ghezzi P, Schmidt HH. Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications. Antioxidants & Redox Signaling. 23: 1171-85. PMID 26583264 DOI: 10.1089/ars.2015.6433  0.84
2015 Buendia I, Navarro E, Michalska P, Gameiro I, Egea J, Abril S, López A, González-Lafuente L, López MG, León R. New melatonin-cinnamate hybrids as multi-target drugs for neurodegenerative diseases: Nrf2-induction, antioxidant effect and neuroprotection. Future Medicinal Chemistry. PMID 26496465 DOI: 10.4155/fmc.15.99  0.84
2015 Moreno-Ortega AJ, Buendia I, Mouhid L, Egea J, Lucea S, Ruiz-Nuño A, López MG, Cano-Abad MF. CALHM1 and its polymorphism P86L differentially control Ca(2+) homeostasis, mitogen-activated protein kinase signaling, and cell vulnerability upon exposure to amyloid β. Aging Cell. PMID 26416646 DOI: 10.1111/acel.12403  0.84
2015 Egea J, Buendia I, Parada E, Navarro E, León R, Lopez MG. Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection. Biochemical Pharmacology. 97: 463-72. PMID 26232730 DOI: 10.1016/j.bcp.2015.07.032  0.84
2015 Navarro E, Buendia I, Parada E, León R, Jansen-Duerr P, Pircher H, Egea J, Lopez MG. Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase I induction. Biochemical Pharmacology. 97: 473-81. PMID 26212551 DOI: 10.1016/j.bcp.2015.07.022  0.84
2015 Buendia I, Gómez-Rangel V, González-Lafuente L, Parada E, León R, Gameiro I, Michalska P, Laudon M, Egea J, López MG. Neuroprotective mechanism of the novel melatonin derivative Neu-P11 in brain ischemia related models. Neuropharmacology. 99: 187-195. PMID 26188145 DOI: 10.1016/j.neuropharm.2015.07.014  0.84
2015 Buendia I, Parada E, Navarro E, León R, Negredo P, Egea J, López MG. Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures. Molecular Neurobiology. PMID 26081146 DOI: 10.1007/s12035-015-9272-5  0.84
2015 Parada E, Buendia I, Navarro E, Avendaño C, Egea J, López MG. Microglial HO-1 induction by curcumin provides antioxidant, antineuroinflammatory, and glioprotective effects. Molecular Nutrition & Food Research. 59: 1690-700. PMID 26047311 DOI: 10.1002/mnfr.201500279  0.84
2015 Freitas AE, Egea J, Buendia I, Gómez-Rangel V, Parada E, Navarro E, Casas AI, Wojnicz A, Ortiz JA, Cuadrado A, Ruiz-Nuño A, Rodrigues AL, Lopez MG. Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice. Molecular Neurobiology. PMID 25966970 DOI: 10.1007/s12035-015-9182-6  0.84
2015 Chioua M, Pérez M, Bautista-Aguilera OM, Yañez M, López MG, Romero A, Cacabelos R, de la Bellacasa RP, Brogi S, Butini S, Borrell JI, Marco-Contelles J. Development of HuperTacrines as non-toxic, cholinesterase inhibitors for the potential treatment of Alzheimer's disease. Mini Reviews in Medicinal Chemistry. 15: 648-58. PMID 25694076  0.84
2015 Guerra-Álvarez M, Moreno-Ortega AJ, Navarro E, Fernández-Morales JC, Egea J, López MG, Cano-Abad MF. Positive allosteric modulation of alpha-7 nicotinic receptors promotes cell death by inducing Ca(2+) release from the endoplasmic reticulum. Journal of Neurochemistry. 133: 309-19. PMID 25650007 DOI: 10.1111/jnc.13049  0.84
2015 Cunha MP, Pazini FL, Ludka FK, Rosa JM, Oliveira Á, Budni J, Ramos-Hryb AB, Lieberknecht V, Bettio LE, Martín-de-Saavedra MD, López MG, Tasca CI, Rodrigues AL. The modulation of NMDA receptors and L-arginine/nitric oxide pathway is implicated in the anti-immobility effect of creatine in the tail suspension test. Amino Acids. 47: 795-811. PMID 25555469 DOI: 10.1007/s00726-014-1910-0  0.84
2015 Benchekroun M, Bartolini M, Egea J, Romero A, Soriano E, Pudlo M, Luzet V, Andrisano V, Jimeno ML, López MG, Wehle S, Gharbi T, Refouvelet B, de Andrés L, Herrera-Arozamena C, et al. Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids. Chemmedchem. 10: 523-39. PMID 25537267 DOI: 10.1002/cmdc.201402409  0.84
2015 Egea J, Buendia I, Parada E, Navarro E, Rada P, Cuadrado A, López MG, García AG, León R. Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of action. British Journal of Pharmacology. 172: 1807-21. PMID 25425158 DOI: 10.1111/bph.13025  0.84
2015 Buendia I, Egea J, Parada E, Navarro E, León R, Rodríguez-Franco MI, López MG. The melatonin-N,N-dibenzyl(N-methyl)amine hybrid ITH91/IQM157 affords neuroprotection in an in vitro Alzheimer's model via hemo-oxygenase-1 induction. Acs Chemical Neuroscience. 6: 288-96. PMID 25393881 DOI: 10.1021/cn5002073  0.84
2015 Mellado-Mojica E, López MG. Identification, classification, and discrimination of agave syrups from natural sweeteners by infrared spectroscopy and HPAEC-PAD. Food Chemistry. 167: 349-57. PMID 25148997 DOI: 10.1016/j.foodchem.2014.06.111  0.68
2015 Freitas AE, Egea J, Buendía I, Navarro E, Rada P, Cuadrado A, Rodrigues AL, López MG. Agmatine induces Nrf2 and protects against corticosterone effects in hippocampal neuronal cell line. Molecular Neurobiology. 51: 1504-19. PMID 25084759 DOI: 10.1007/s12035-014-8827-1  0.84
2015 Freitas AE, Egea J, Buendia I, Gómez-Rangel V, Parada E, Navarro E, Casas AI, Wojnicz A, Ortiz JA, Cuadrado A, Ruiz-Nuño A, Rodrigues ALS, Lopez MG. Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice Molecular Neurobiology. DOI: 10.1007/s12035-015-9182-6  0.84
2014 Cherif O, Allouche F, Chabchoub F, Chioua M, Soriano E, Yañez M, Cacabelos R, Romero A, López MG, Marco-Contelles J. Isoxazolotacrines as non-toxic and selective butyrylcholinesterase inhibitors for Alzheimer's disease. Future Medicinal Chemistry. 6: 1883-91. PMID 25495982 DOI: 10.4155/fmc.14.115  0.84
2014 Cunha MP, Martín-de-Saavedra MD, Romero A, Egea J, Ludka FK, Tasca CI, Farina M, Rodrigues AL, López MG. Both creatine and its product phosphocreatine reduce oxidative stress and afford neuroprotection in an in vitro Parkinson's model. Asn Neuro. 6. PMID 25424428 DOI: 10.1177/1759091414554945  0.84
2014 Santiago-García PA, López MG. Agavins from Agave angustifolia and Agave potatorum affect food intake, body weight gain and satiety-related hormones (GLP-1 and ghrelin) in mice. Food & Function. 5: 3311-9. PMID 25367106 DOI: 10.1039/c4fo00561a  0.68
2014 Balsera B, Mulet J, Fernández-Carvajal A, de la Torre-Martínez R, Ferrer-Montiel A, Hernández-Jiménez JG, Estévez-Herrera J, Borges R, Freitas AE, López MG, García-López MT, González-Muñiz R, Pérez de Vega MJ, Valor LM, Svobodová L, et al. Chalcones as positive allosteric modulators of α7 nicotinic acetylcholine receptors: a new target for a privileged structure. European Journal of Medicinal Chemistry. 86: 724-39. PMID 25232969 DOI: 10.1016/j.ejmech.2014.09.039  0.84
2014 García-Vieyra MI, Del Real A, López MG. Agave fructans: their effect on mineral absorption and bone mineral content. Journal of Medicinal Food. 17: 1247-55. PMID 25069021 DOI: 10.1089/jmf.2013.0137  0.68
2014 Romero A, Egea J, González-Muñoz GC, Martín de Saavedra MD, del Barrio L, Rodríguez-Franco MI, Conde S, López MG, Villarroya M, de los Ríos C. ITH12410/SC058: a new neuroprotective compound with potential in the treatment of Alzheimer's disease. Acs Chemical Neuroscience. 5: 770-5. PMID 25008046 DOI: 10.1021/cn500131t  0.84
2014 González-Muñoz GC, Arce MP, Pérez C, Romero A, Villarroya M, López MG, Conde S, Rodríguez-Franco MI. Dibenzo[1,4,5]thiadiazepine: a hardly-known heterocyclic system with neuroprotective properties of potential usefulness in the treatment of neurodegenerative diseases. European Journal of Medicinal Chemistry. 81: 350-8. PMID 24858540 DOI: 10.1016/j.ejmech.2014.04.075  0.68
2014 Tenti G, Parada E, León R, Egea J, Martínez-Revelles S, Briones AM, Sridharan V, López MG, Ramos MT, Menéndez JC. New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury. Journal of Medicinal Chemistry. 57: 4313-23. PMID 24754640 DOI: 10.1021/jm500263v  0.84
2014 López-Iglesias B, Pérez C, Morales-García JA, Alonso-Gil S, Pérez-Castillo A, Romero A, López MG, Villarroya M, Conde S, Rodríguez-Franco MI. New melatonin-N,N-dibenzyl(N-methyl)amine hybrids: potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease. Journal of Medicinal Chemistry. 57: 3773-85. PMID 24738476 DOI: 10.1021/jm5000613  0.68
2014 Egea J, Romero A, Parada E, León R, Dal-Cim T, López MG. Neuroprotective effect of dimebon against ischemic neuronal damage. Neuroscience. 267: 11-21. PMID 24607349 DOI: 10.1016/j.neuroscience.2014.02.025  0.84
2014 Rojo AI, McBean G, Cindric M, Egea J, López MG, Rada P, Zarkovic N, Cuadrado A. Redox control of microglial function: molecular mechanisms and functional significance. Antioxidants & Redox Signaling. 21: 1766-801. PMID 24597893 DOI: 10.1089/ars.2013.5745  0.84
2014 Egea J, Parada E, Gómez-Rangel V, Buendia I, Negredo P, Montell E, Ruhí R, Vergés J, Roda JM, García AG, López MG. Small synthetic hyaluronan disaccharides afford neuroprotection in brain ischemia-related models. Neuroscience. 265: 313-22. PMID 24486437 DOI: 10.1016/j.neuroscience.2014.01.032  0.84
2014 Parada E, Buendia I, León R, Negredo P, Romero A, Cuadrado A, López MG, Egea J. Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression. Journal of Pineal Research. 56: 204-12. PMID 24350834 DOI: 10.1111/jpi.12113  0.84
2014 Suárez-González EM, López MG, Délano-Frier JP, Gómez-Leyva JF. Expression of the 1-SST and 1-FFT genes and consequent fructan accumulation in Agave tequilana and A. inaequidens is differentially induced by diverse (a)biotic-stress related elicitors. Journal of Plant Physiology. 171: 359-72. PMID 23988562 DOI: 10.1016/j.jplph.2013.08.002  0.68
2013 Lopez LA, Ibarra BS, de la Garza JA, Rada Fde J, Nuñez AI, López MG. First reported case of pneumonia caused by Cedecea lapagei in America. The Brazilian Journal of Infectious Diseases : An Official Publication of the Brazilian Society of Infectious Diseases. 17: 626-8. PMID 24035464 DOI: 10.1016/j.bjid.2013.03.003  0.68
2013 Lorrio S, Romero A, González-Lafuente L, Lajarín-Cuesta R, Martínez-Sanz FJ, Estrada M, Samadi A, Marco-Contelles J, Rodríguez-Franco MI, Villarroya M, López MG, de los Ríos C. PP2A ligand ITH12246 protects against memory impairment and focal cerebral ischemia in mice. Acs Chemical Neuroscience. 4: 1267-77. PMID 23763493 DOI: 10.1021/cn400050p  0.68
2013 Dal-Cim T, Ludka FK, Martins WC, Reginato C, Parada E, Egea J, López MG, Tasca CI. Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions. Journal of Neurochemistry. 126: 437-50. PMID 23713463 DOI: 10.1111/jnc.12324  0.84
2013 Martín-de-Saavedra MD, Budni J, Cunha MP, Gómez-Rangel V, Lorrio S, Del Barrio L, Lastres-Becker I, Parada E, Tordera RM, Rodrigues AL, Cuadrado A, López MG. Nrf2 participates in depressive disorders through an anti-inflammatory mechanism. Psychoneuroendocrinology. 38: 2010-22. PMID 23623252 DOI: 10.1016/j.psyneuen.2013.03.020  0.84
2013 Cunha MP, Martín-de-Saavedra MD, Romero A, Parada E, Egea J, Del Barrio L, Rodrigues AL, López MG. Protective effect of creatine against 6-hydroxydopamine-induced cell death in human neuroblastoma SH-SY5Y cells: Involvement of intracellular signaling pathways. Neuroscience. 238: 185-94. PMID 23485810 DOI: 10.1016/j.neuroscience.2013.02.030  0.84
2013 Jacques AV, Rieger DK, Maestri M, Lopes MW, Peres TV, Gonçalves FM, Pedro DZ, Tasca CI, López MG, Egea J, Nascimento KS, Cavada BS, Leal RB. Lectin from Canavalia brasiliensis (ConBr) protects hippocampal slices against glutamate neurotoxicity in a manner dependent of PI3K/Akt pathway. Neurochemistry International. 62: 836-42. PMID 23454192 DOI: 10.1016/j.neuint.2013.02.020  0.84
2013 Romero A, Gomez-Rangel V, Egea J, Samadi A, Marco-Contelles J, Lopez MG. Enantioselective neuroprotective effects of Tacripyrine ITH122 against oxygen and glucose deprivation in rat hippocampal slices. Cns Neuroscience & Therapeutics. 19: 285-7. PMID 23441748 DOI: 10.1111/cns.12073  0.84
2013 Barros-Miñones L, Martín-de-Saavedra D, Perez-Alvarez S, Orejana L, Suquía V, Goñi-Allo B, Hervias I, López MG, Jordan J, Aguirre N, Puerta E. Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate. Biochimica Et Biophysica Acta. 1832: 705-17. PMID 23415811 DOI: 10.1016/j.bbadis.2013.02.002  0.84
2013 Parada E, Egea J, Buendia I, Negredo P, Cunha AC, Cardoso S, Soares MP, López MG. The microglial α7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2. Antioxidants & Redox Signaling. 19: 1135-48. PMID 23311871 DOI: 10.1089/ars.2012.4671  0.84
2013 Lorrio S, Gómez-Rangel V, Negredo P, Egea J, Leon R, Romero A, Dal-Cim T, Villarroya M, Rodriguez-Franco MI, Conde S, Arce MP, Roda JM, García AG, López MG. Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia. Neuropharmacology. 67: 403-11. PMID 23228428 DOI: 10.1016/j.neuropharm.2012.12.001  0.84
2013 Berretta MF, López MG, Taboga O, Sciocco-Cap A, Romanowski V. Functional analysis of Spodoptera frugiperda nucleopolyhedrovirus late expression factors in Sf9 cells. Virus Genes. 46: 152-61. PMID 23124597 DOI: 10.1007/s11262-012-0843-5  0.68
2012 Ángeles López YI, Martínez-Gallardo NA, Ramírez-Romero R, López MG, Sánchez-Hernández C, Délano-Frier JP. Cross-kingdom effects of plant-plant signaling via volatile organic compounds emitted by tomato (Solanum lycopersicum) plants infested by the greenhouse whitefly (Trialeurodes vaporariorum). Journal of Chemical Ecology. 38: 1376-86. PMID 23085855 DOI: 10.1007/s10886-012-0201-z  0.68
2012 Mellado-Mojica E, López MG. Fructan metabolism in A. tequilana Weber Blue variety along its developmental cycle in the field. Journal of Agricultural and Food Chemistry. 60: 11704-13. PMID 23072425 DOI: 10.1021/jf303332n  0.68
2012 Alfonso V, Maroniche GA, Reca SR, López MG, del Vas M, Taboga O. AcMNPV core gene ac109 is required for budded virion transport to the nucleus and for occlusion of viral progeny. Plos One. 7: e46146. PMID 23049963 DOI: 10.1371/journal.pone.0046146  0.68
2012 Barreira RI, García BB, López MG, Legazpi IR, Díaz HÁ, Penín IR. Paradoxical reaction of raynaud phenomenon following the repeated administration of iloprost in a patient with diffuse cutaneous systemic sclerosis. The Annals of Pharmacotherapy. 46: e28. PMID 23032649 DOI: 10.1345/aph.1R093  0.68
2012 González-Lafuente L, Egea J, León R, Martínez-Sanz FJ, Monjas L, Perez C, Merino C, García-De Diego AM, Rodríguez-Franco MI, García AG, Villarroya M, López MG, de Los Ríos C. Benzothiazepine CGP37157 and its isosteric 2'-methyl analogue provide neuroprotection and block cell calcium entry. Acs Chemical Neuroscience. 3: 519-29. PMID 22860221 DOI: 10.1021/cn300009e  0.84
2012 Dal-Cim T, Molz S, Egea J, Parada E, Romero A, Budni J, Martín de Saavedra MD, del Barrio L, Tasca CI, López MG. Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway. Neurochemistry International. 61: 397-404. PMID 22683349 DOI: 10.1016/j.neuint.2012.05.021  0.84
2012 Cortés-Romero C, Martínez-Hernández A, Mellado-Mojica E, López MG, Simpson J. Molecular and functional characterization of novel fructosyltransferases and invertases from Agave tequilana. Plos One. 7: e35878. PMID 22558253 DOI: 10.1371/journal.pone.0035878  0.68
2012 Alfonzo MA, Diaz A, Siciliano L, López MG, Hung A, Garcia JF. Functional state of CD4+ and CD8+ T lymphocytes and their role in the slow progression of HIV infection in pediatric patients. Jornal De Pediatria. 88: 161-8. PMID 22543625 DOI: doi:10.2223/JPED.2183  0.68
2012 Stegmayer G, Milone DH, Kamenetzky L, López MG, Carrari F. A biologically inspired validity measure for comparison of clustering methods over metabolic data sets. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 9: 706-16. PMID 22231623 DOI: 10.1109/TCBB.2012.10  0.68
2012 Egea J, Malmierca E, Rosa AO, del Barrio L, Negredo P, Nuñez A, López MG. Participation of calbindin-D28K in nociception: results from calbindin-D28K knockout mice. PflüGers Archiv : European Journal of Physiology. 463: 449-58. PMID 22134771 DOI: 10.1007/s00424-011-1063-x  0.84
2012 Egea J, Martín-de-Saavedra MD, Parada E, Romero A, Del Barrio L, Rosa AO, García AG, López MG. Galantamine elicits neuroprotection by inhibiting iNOS, NADPH oxidase and ROS in hippocampal slices stressed with anoxia/reoxygenation. Neuropharmacology. 62: 1082-90. PMID 22085833 DOI: 10.1016/j.neuropharm.2011.10.022  0.84
2012 Budni J, Lobato KR, Binfaré RW, Freitas AE, Costa AP, Martín-de-Saavedra MD, Leal RB, Lopez MG, Rodrigues AL. Involvement of PI3K, GSK-3β and PPARγ in the antidepressant-like effect of folic acid in the forced swimming test in mice. Journal of Psychopharmacology (Oxford, England). 26: 714-23. PMID 22037925 DOI: 10.1177/0269881111424456  0.84
2011 Bartolini M, Pistolozzi M, Andrisano V, Egea J, López MG, Iriepa I, Moraleda I, Gálvez E, Marco-Contelles J, Samadi A. Chemical and pharmacological studies on enantiomerically pure p-methoxytacripyrines, promising multi-target-directed ligands for the treatment of Alzheimer's disease. Chemmedchem. 6: 1990-7. PMID 21990269 DOI: 10.1002/cmdc.201100239  0.84
2011 Del Barrio L, Martín-de-Saavedra MD, Romero A, Parada E, Egea J, Avila J, McIntosh JM, Wonnacott S, López MG. Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation. Toxicological Sciences : An Official Journal of the Society of Toxicology. 123: 193-205. PMID 21715663 DOI: 10.1093/toxsci/kfr163  0.84
2011 Silva D, Chioua M, Samadi A, Carmo Carreiras M, Jimeno ML, Mendes E, Ríos Cde L, Romero A, Villarroya M, López MG, Marco-Contelles J. Synthesis and pharmacological assessment of diversely substituted pyrazolo[3,4-b]quinoline, and benzo[b]pyrazolo[4,3-g][1,8]naphthyridine derivatives. European Journal of Medicinal Chemistry. 46: 4676-81. PMID 21715067 DOI: 10.1016/j.ejmech.2011.05.068  0.68
2011 Molz S, Dal-Cim T, Budni J, Martín-de-Saavedra MD, Egea J, Romero A, del Barrio L, Rodrigues AL, López MG, Tasca CI. Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition. Journal of Neuroscience Research. 89: 1400-8. PMID 21671255 DOI: 10.1002/jnr.22681  0.84
2011 Budni J, Romero A, Molz S, Martín-de-Saavedra MD, Egea J, Del Barrio L, Tasca CI, Rodrigues AL, López MG. Neurotoxicity induced by dexamethasone in the human neuroblastoma SH-SY5Y cell line can be prevented by folic acid. Neuroscience. 190: 346-53. PMID 21640799 DOI: 10.1016/j.neuroscience.2011.05.053  0.84
2011 González-Muñoz GC, Arce MP, López B, Pérez C, Romero A, del Barrio L, Martín-de-Saavedra MD, Egea J, León R, Villarroya M, López MG, García AG, Conde S, Rodríguez-Franco MI. N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease. European Journal of Medicinal Chemistry. 46: 2224-35. PMID 21420206 DOI: 10.1016/j.ejmech.2011.03.003  0.84
2011 Martín-de-Saavedra MD, del Barrio L, Cañas N, Egea J, Lorrio S, Montell E, Vergés J, García AG, López MG. Chondroitin sulfate reduces cell death of rat hippocampal slices subjected to oxygen and glucose deprivation by inhibiting p38, NFκB and iNOS. Neurochemistry International. 58: 676-83. PMID 21335047 DOI: 10.1016/j.neuint.2011.02.006  0.84
2011 Samadi A, Valderas C, de los Ríos C, Bastida A, Chioua M, González-Lafuente L, Colmena I, Gandía L, Romero A, Del Barrio L, Martín-de-Saavedra MD, López MG, Villarroya M, Marco-Contelles J. Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new tacrine analogues from highly substituted 2-aminopyridine-3-carbonitriles. Bioorganic & Medicinal Chemistry. 19: 122-33. PMID 21163662 DOI: 10.1016/j.bmc.2010.11.040  0.68
2011 del Barrio L, Egea J, León R, Romero A, Ruiz A, Montero M, Alvarez J, López MG. Calcium signalling mediated through α7 and non-α7 nAChR stimulation is differentially regulated in bovine chromaffin cells to induce catecholamine release. British Journal of Pharmacology. 162: 94-110. PMID 20840468 DOI: 10.1111/j.1476-5381.2010.01034.x  0.84
2011 Martins DF, Rosa AO, Gadotti VM, Mazzardo-Martins L, Nascimento FP, Egea J, López MG, Santos AR. The antinociceptive effects of AR-A014418, a selective inhibitor of glycogen synthase kinase-3 beta, in mice. The Journal of Pain : Official Journal of the American Pain Society. 12: 315-22. PMID 20705523 DOI: 10.1016/j.jpain.2010.06.007  0.84
2010 González-Muñoz GC, Arce MP, López B, Pérez C, Villarroya M, López MG, García AG, Conde S, Rodríguez-Franco MI. Old phenothiazine and dibenzothiadiazepine derivatives for tomorrow's neuroprotective therapies against neurodegenerative diseases. European Journal of Medicinal Chemistry. 45: 6152-8. PMID 20926162 DOI: 10.1016/j.ejmech.2010.09.039  0.68
2010 Parada E, Egea J, Romero A, del Barrio L, García AG, López MG. Poststress treatment with PNU282987 can rescue SH-SY5Y cells undergoing apoptosis via α7 nicotinic receptors linked to a Jak2/Akt/HO-1 signaling pathway. Free Radical Biology & Medicine. 49: 1815-21. PMID 20875851 DOI: 10.1016/j.freeradbiomed.2010.09.017  0.84
2010 Nicolau SM, Egea J, López MG, García AG. Mitochondrial Na+/Ca2+ exchanger, a new target for neuroprotection in rat hippocampal slices. Biochemical and Biophysical Research Communications. 400: 140-4. PMID 20713022 DOI: 10.1016/j.bbrc.2010.08.028  0.84
2010 Samadi A, Marco-Contelles J, Soriano E, Alvarez-Pérez M, Chioua M, Romero A, González-Lafuente L, Gandía L, Roda JM, López MG, Villarroya M, García AG, Ríos Cde L. Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles. Bioorganic & Medicinal Chemistry. 18: 5861-72. PMID 20656495 DOI: 10.1016/j.bmc.2010.06.095  0.68
2010 de Los Ríos C, Egea J, Marco-Contelles J, León R, Samadi A, Iriepa I, Moraleda I, Gálvez E, García AG, López MG, Villarroya M, Romero A. Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives. Journal of Medicinal Chemistry. 53: 5129-43. PMID 20575555 DOI: 10.1021/jm901902w  0.84
2010 Fernández-Bachiller MI, Pérez C, González-Muñoz GC, Conde S, López MG, Villarroya M, García AG, Rodríguez-Franco MI. Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties. Journal of Medicinal Chemistry. 53: 4927-37. PMID 20545360 DOI: 10.1021/jm100329q  0.68
2010 Romero A, Egea J, García AG, López MG. Synergistic neuroprotective effect of combined low concentrations of galantamine and melatonin against oxidative stress in SH-SY5Y neuroblastoma cells. Journal of Pineal Research. 49: 141-8. PMID 20536682 DOI: 10.1111/j.1600-079X.2010.00778.x  0.84
2010 Soletti RC, del Barrio L, Daffre S, Miranda A, Borges HL, Moura-Neto V, Lopez MG, Gabilan NH. Peptide gomesin triggers cell death through L-type channel calcium influx, MAPK/ERK, PKC and PI3K signaling and generation of reactive oxygen species. Chemico-Biological Interactions. 186: 135-43. PMID 20433817 DOI: 10.1016/j.cbi.2010.04.012  0.84
2010 Egea J, García AG, Verges J, Montell E, López MG. Antioxidant, antiinflammatory and neuroprotective actions of chondroitin sulfate and proteoglycans. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 18: S24-7. PMID 20399898 DOI: 10.1016/j.joca.2010.01.016  0.84
2010 Cañas N, Gorina R, Planas AM, Vergés J, Montell E, García AG, López MG. Chondroitin sulfate inhibits lipopolysaccharide-induced inflammation in rat astrocytes by preventing nuclear factor kappa B activation. Neuroscience. 167: 872-9. PMID 20206237 DOI: 10.1016/j.neuroscience.2010.02.069  0.68
2010 Araújo CV, Tornero V, Lubián LM, Blasco J, van Bergeijk SA, Cañavate P, Cid A, Franco D, Prado R, Bartual A, López MG, Ribeiro R, Moreira-Santos M, Torreblanca A, Jurado B, et al. Ring test for whole-sediment toxicity assay with -a- benthic marine diatom. The Science of the Total Environment. 408: 822-8. PMID 19906403 DOI: 10.1016/j.scitotenv.2009.10.018  0.68
2009 Arce MP, Rodríguez-Franco MI, González-Muñoz GC, Pérez C, López B, Villarroya M, López MG, García AG, Conde S. Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease. Journal of Medicinal Chemistry. 52: 7249-57. PMID 19856923 DOI: 10.1021/jm900628z  0.68
2009 Egea J, Rosa AO, Lorrio S, del Barrio L, Cuadrado A, López MG. Haeme oxygenase-1 overexpression via nAChRs and the transcription factor Nrf2 has antinociceptive effects in the formalin test. Pain. 146: 75-83. PMID 19660867 DOI: 10.1016/j.pain.2009.07.007  0.84
2009 Bivián-Castro EY, López MG, Pedraza-Reyes M, Bernès S, Mendoza-Díaz G. Synthesis, characterization, and biological activity studies of copper(II) mixed compound with histamine and nalidixic acid. Bioinorganic Chemistry and Applications. 603651. PMID 19557138 DOI: 10.1155/2009/603651  0.68
2009 Nicolau SM, de Diego AM, Cortés L, Egea J, González JC, Mosquera M, López MG, Hernández-Guijo JM, García AG. Mitochondrial Na+/Ca2+-exchanger blocker CGP37157 protects against chromaffin cell death elicited by veratridine. The Journal of Pharmacology and Experimental Therapeutics. 330: 844-54. PMID 19509314 DOI: 10.1124/jpet.109.154765  0.84
2009 Lachenmeier DW, Kanteres F, Kuballa T, López MG, Rehm J. Ethyl carbamate in alcoholic beverages from Mexico (tequila, mezcal, bacanora, sotol) and Guatemala (cuxa): market survey and risk assessment. International Journal of Environmental Research and Public Health. 6: 349-60. PMID 19440288 DOI: 10.3390/ijerph6010349  0.68
2009 Marco-Contelles J, León R, de los Ríos C, Samadi A, Bartolini M, Andrisano V, Huertas O, Barril X, Luque FJ, Rodríguez-Franco MI, López B, López MG, García AG, Carreiras Mdo C, Villarroya M. Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease. Journal of Medicinal Chemistry. 52: 2724-32. PMID 19374444 DOI: 10.1021/jm801292b  0.84
2009 Fernández-Bachiller MI, Pérez C, Campillo NE, Páez JA, González-Muñoz GC, Usán P, García-Palomero E, López MG, Villarroya M, García AG, Martínez A, Rodríguez-Franco MI. Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties. Chemmedchem. 4: 828-41. PMID 19308922 DOI: 10.1002/cmdc.200800414  0.68
2009 Valero T, del Barrio L, Egea J, Cañas N, Martínez A, García AG, Villarroya M, López MG. NP04634 prevents cell damage caused by calcium overload and mitochondrial disruption in bovine chromaffin cells. European Journal of Pharmacology. 607: 47-53. PMID 19233161 DOI: 10.1016/j.ejphar.2009.02.021  0.84
2009 Burgos-Ramos E, Martos-Moreno GA, López MG, Herranz R, Aguado-Llera D, Egea J, Frechilla D, Cenarruzabeitia E, León R, Arilla-Ferreiro E, Argente J, Barrios V. The N-terminal tripeptide of insulin-like growth factor-I protects against beta-amyloid-induced somatostatin depletion by calcium and glycogen synthase kinase 3 beta modulation. Journal of Neurochemistry. 109: 360-70. PMID 19220704 DOI: 10.1111/j.1471-4159.2009.05980.x  0.84
2009 Lorrio S, Negredo P, Roda JM, García AG, López MG. Effects of memantine and galantamine given separately or in association, on memory and hippocampal neuronal loss after transient global cerebral ischemia in gerbils. Brain Research. 1254: 128-37. PMID 19103181 DOI: 10.1016/j.brainres.2008.11.095  0.68
2009 Robles-Zepeda RE, Lozoya-Gloria E, López MG, Villarreal ML, Ramírez-Chávez E, Molina-Torres J. Montanoa tomentosa glandular trichomes containing kaurenoic acids chemical profile and distribution. Fitoterapia. 80: 12-7. PMID 18824221 DOI: 10.1016/j.fitote.2008.09.002  0.68
2008 León R, de los Ríos C, Marco-Contelles J, Huertas O, Barril X, Luque FJ, López MG, García AG, Villarroya M. New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties. Bioorganic & Medicinal Chemistry. 16: 7759-69. PMID 18640842 DOI: 10.1016/j.bmc.2008.07.005  0.68
2008 Rojo AI, Rada P, Egea J, Rosa AO, López MG, Cuadrado A. Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal cell death. Molecular and Cellular Neurosciences. 39: 125-32. PMID 18619545 DOI: 10.1016/j.mcn.2008.06.007  0.84
2008 Rosa AO, Kaster MP, Binfaré RW, Morales S, Martín-Aparicio E, Navarro-Rico ML, Martinez A, Medina M, García AG, López MG, Rodrigues AL. Antidepressant-like effect of the novel thiadiazolidinone NP031115 in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 32: 1549-56. PMID 18579278 DOI: 10.1016/j.pnpbp.2008.05.020  0.84
2008 Rosa AO, Egea J, Martínez A, García AG, López MG. Neuroprotective effect of the new thiadiazolidinone NP00111 against oxygen-glucose deprivation in rat hippocampal slices: implication of ERK1/2 and PPARgamma receptors. Experimental Neurology. 212: 93-9. PMID 18471812 DOI: 10.1016/j.expneurol.2008.03.008  0.84
2008 Díaz-Prieto N, Herrera-Peco I, de Diego AM, Ruiz-Nuño A, Gallego-Sandín S, López MG, García AG, Cano-Abad MF. Bcl2 mitigates Ca2+ entry and mitochondrial Ca2+ overload through downregulation of L-type Ca2+ channels in PC12 cells. Cell Calcium. 44: 339-52. PMID 18346784 DOI: 10.1016/j.ceca.2008.01.007  0.84
2008 del Rosario Abraham-Juárez M, del Carmen Rocha-Granados M, López MG, Rivera-Bustamante RF, Ochoa-Alejo N. Virus-induced silencing of Comt, pAmt and Kas genes results in a reduction of capsaicinoid accumulation in chili pepper fruits. Planta. 227: 681-95. PMID 17999078 DOI: 10.1007/s00425-007-0651-7  0.68
2008 Rosa AO, Egea J, Lorrio S, Rojo AI, Cuadrado A, López MG. Nrf2-mediated haeme oxygenase-1 up-regulation induced by cobalt protoporphyrin has antinociceptive effects against inflammatory pain in the formalin test in mice. Pain. 137: 332-9. PMID 17964723 DOI: 10.1016/j.pain.2007.09.015  0.84
2008 Urías-Silvas JE, Cani PD, Delmée E, Neyrinck A, López MG, Delzenne NM. Physiological effects of dietary fructans extracted from Agave tequilana Gto. and Dasylirion spp. The British Journal of Nutrition. 99: 254-61. PMID 17711612 DOI: 10.1017/S0007114507795338  0.68
2008 León R, de Los Ríos C, Marco-Contelles J, López MG, García AG, Villarroya M. Synthesis of 6-amino-1,4-dihydropyridines that prevent calcium overload and neuronal death. European Journal of Medicinal Chemistry. 43: 668-74. PMID 17692434 DOI: 10.1016/j.ejmech.2007.06.001  0.68
2007 Villarroya M, García AG, Marco-Contelles J, López MG. An update on the pharmacology of galantamine. Expert Opinion On Investigational Drugs. 16: 1987-98. PMID 18042006 DOI: 10.1517/13543784.16.12.1987  0.68
2007 Cañas N, Valero T, Villarroya M, Montell E, Vergés J, García AG, López MG. Chondroitin sulfate protects SH-SY5Y cells from oxidative stress by inducing heme oxygenase-1 via phosphatidylinositol 3-kinase/Akt. The Journal of Pharmacology and Experimental Therapeutics. 323: 946-53. PMID 17885094 DOI: 10.1124/jpet.107.123505  0.68
2007 Egea J, Rosa AO, Cuadrado A, García AG, López MG. Nicotinic receptor activation by epibatidine induces heme oxygenase-1 and protects chromaffin cells against oxidative stress. Journal of Neurochemistry. 102: 1842-52. PMID 17540012 DOI: 10.1111/j.1471-4159.2007.04665.x  0.84
2007 Lorrio S, Sobrado M, Arias E, Roda JM, García AG, López MG. Galantamine postischemia provides neuroprotection and memory recovery against transient global cerebral ischemia in gerbils. The Journal of Pharmacology and Experimental Therapeutics. 322: 591-9. PMID 17526807 DOI: 10.1124/jpet.107.122747  0.68
2007 Egea J, Rosa AO, Sobrado M, Gandía L, López MG, García AG. Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in alpha7 nicotinic receptor knockout mice. Neuroscience. 145: 866-72. PMID 17291692 DOI: 10.1016/j.neuroscience.2006.12.036  0.84
2006 López MG, Arias E, Sobrado M, Lorrio S, Roda JM, García AG. Can cholinesterase inhibitors provide additional effects to cholinergic neurotransmission enhancement? Journal of Molecular Neuroscience : Mn. 30: 141-4. PMID 17192661 DOI: 10.1385/JMN:30:1:141  0.68
2006 Rosa AO, Egea J, Gandía L, López MG, García AG. Neuroprotection by nicotine in hippocampal slices subjected to oxygen-glucose deprivation: involvement of the alpha7 nAChR subtype. Journal of Molecular Neuroscience : Mn. 30: 61-2. PMID 17192628 DOI: 10.1385/JMN:30:1:61  0.84
2006 Egea J, Hernández-Guijo JM, Olivares R, López MG, García AG. Desensitized nicotinic receptors that, however, afford cytoprotection in bovine chromaffin cells. Journal of Molecular Neuroscience : Mn. 30: 59-60. PMID 17192627 DOI: 10.1385/JMN:30:1:59  0.84
2006 Marco-Contelles J, León R, de Los Ríos C, Guglietta A, Terencio J, López MG, García AG, Villarroya M. Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease. Journal of Medicinal Chemistry. 49: 7607-10. PMID 17181144 DOI: 10.1021/jm061047j  0.68
2006 Sánchez-Hernández C, López MG, Délano-Frier JP. Reduced levels of volatile emissions in jasmonate-deficient spr2 tomato mutants favour oviposition by insect herbivores. Plant, Cell & Environment. 29: 546-57. PMID 17080606  0.68
2006 Orozco C, García-de-Diego AM, Arias E, Hernández-Guijo JM, García AG, Villarroya M, López MG. Depolarization preconditioning produces cytoprotection against veratridine-induced chromaffin cell death. European Journal of Pharmacology. 553: 28-38. PMID 17045260 DOI: 10.1016/j.ejphar.2006.08.084  0.68
2006 Marco-Contelles J, León R, López MG, García AG, Villarroya M. Synthesis and biological evaluation of new 4H-pyrano[2,3-b]quinoline derivatives that block acetylcholinesterase and cell calcium signals, and cause neuroprotection against calcium overload and free radicals. European Journal of Medicinal Chemistry. 41: 1464-9. PMID 17030484 DOI: 10.1016/j.ejmech.2006.06.016  0.68
2006 Marco-Contelles J, León R, de los Ríos C, García AG, López MG, Villarroya M. New multipotent tetracyclic tacrines with neuroprotective activity. Bioorganic & Medicinal Chemistry. 14: 8176-85. PMID 17005406 DOI: 10.1016/j.bmc.2006.09.025  0.68
2006 Mancilla-Margalli NA, López MG. Water-soluble carbohydrates and fructan structure patterns from Agave and Dasylirion species. Journal of Agricultural and Food Chemistry. 54: 7832-9. PMID 17002459 DOI: 10.1021/jf060354v  0.68
2006 Alés E, Gullo F, Arias E, Olivares R, García AG, Wanke E, López MG. Blockade of Ca2+ -activated K+ channels by galantamine can also contribute to the potentiation of catecholamine secretion from chromaffin cells. European Journal of Pharmacology. 548: 45-52. PMID 16949070 DOI: 10.1016/j.ejphar.2006.07.032  0.68
2006 Nila AG, Sandalio LM, López MG, Gómez M, del Rio LA, Gómez-Lim MA. Expression of a peroxisome proliferator-activated receptor gene (xPPARalpha) from Xenopus laevis in tobacco (Nicotiana tabacum) plants. Planta. 224: 569-81. PMID 16738865 DOI: 10.1007/s00425-006-0246-8  0.68
2006 Lachenmeier DW, Sohnius EM, Attig R, López MG. Quantification of selected volatile constituents and anions in Mexican Agave spirits (Tequila, Mezcal, Sotol, Bacanora). Journal of Agricultural and Food Chemistry. 54: 3911-5. PMID 16719514 DOI: 10.1021/jf060094h  0.68
2006 Díez-Domingo J, Martín IO, Sanz AB, López AG, Martínez CC, Boronat CP, Del Barrio MJ, García DG, Pons MM, Crespo VA, Esteve PA, Arfella IL, Monrabal IS, Baveira LB, López MG. Rotavirus gastroenteritis among children under five years of age in Valencia, Spain. The Pediatric Infectious Disease Journal. 25: 455-7. PMID 16645514 DOI: 10.1097/01.inf.0000217378.30444.21  0.68
2006 De León-Rodríguez A, González-Hernández L, Barba de la Rosa AP, Escalante-Minakata P, López MG. Characterization of volatile compounds of Mezcal, an ethnic alcoholic beverage obtained from Agave salmiana. Journal of Agricultural and Food Chemistry. 54: 1337-41. PMID 16478257 DOI: 10.1021/jf052154+  0.68
2006 Villarroya M, López MG, Cano-Abad MF, García AG. Measurement of Ca2+ entry using 45Ca2+. Methods in Molecular Biology (Clifton, N.J.). 312: 135-45. PMID 16422195  0.84
2006 Almeida RC, Felisbino CS, López MG, Rodrigues AL, Gabilan NH. Evidence for the involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of memantine in mice. Behavioural Brain Research. 168: 318-22. PMID 16387371 DOI: 10.1016/j.bbr.2005.11.023  0.68
2006 Almeida RC, Souza DG, Soletti RC, López MG, Rodrigues AL, Gabilan NH. Involvement of PKA, MAPK/ERK and CaMKII, but not PKC in the acute antidepressant-like effect of memantine in mice. Neuroscience Letters. 395: 93-7. PMID 16289784 DOI: 10.1016/j.neulet.2005.10.057  0.84
2005 Villarroya M, López MG, Cano-Abad MF, García AG. Measurement of Ca²+ entry using ⁴⁵Ca²+. Methods in Molecular Biology (Clifton, N.J.). 312: 135-45. PMID 21341096 DOI: 10.1385/1-59259-949-4:135  0.84
2005 Morales AP, Conde EG, López MG, Valle MI, Díaz JF, Jáuregui PH. An improved method of 90% pancreatectomy using a low dose of streptozotocin at the pancreaticoduodenal artery results in a rapid diabetic stage in dogs. Acta Diabetologica. 42: 153-5. PMID 16382301 DOI: 10.1007/s00592-005-0195-x  0.68
2005 Arias E, Gallego-Sandín S, Villarroya M, García AG, López MG. Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: role of nicotinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 315: 1346-53. PMID 16144975 DOI: 10.1124/jpet.105.090365  0.68
2005 Villarroya M, López MG, de Pascual R, García AG. Preclinical profile of PF9404C, a nitric oxide donor with beta receptor blocking properties. Cardiovascular Drug Reviews. 23: 149-60. PMID 16007231  0.68
2005 Lachenmeier DW, Richling E, López MG, Frank W, Schreier P. Multivariate analysis of FTIR and ion chromatographic data for the quality control of tequila. Journal of Agricultural and Food Chemistry. 53: 2151-7. PMID 15769149 DOI: 10.1021/jf048637f  0.68
2005 López MG, Peralta A, Berinstein A, Fondevila N, Carrillo E, Taboga O. High-level expression of recombinant 3AB1 non-structural protein from FMDV in insect larvae. Journal of Virological Methods. 124: 221-4. PMID 15664073 DOI: 10.1016/j.jviromet.2004.11.004  0.68
2005 Alés E, Fuentealba J, García AG, López MG. Depolarization evokes different patterns of calcium signals and exocytosis in bovine and mouse chromaffin cells: the role of mitochondria. The European Journal of Neuroscience. 21: 142-50. PMID 15654851 DOI: 10.1111/j.1460-9568.2004.03861.x  0.68
2004 López MG, Mellado PT, Huete IL. [Malignant infarct of the middle cerebral artery in a patient with bacterial meningitis]. Revista MéDica De Chile. 132: 1217-20. PMID 15631210  0.68
2004 Ruiz-Nuño A, Rosado A, García AG, López MG, Villarroya M. Differences in the vascular selectivity and tolerance between the NO donor/beta-blocker PF9404C and nitroglycerin. European Journal of Pharmacology. 498: 203-10. PMID 15363996 DOI: 10.1016/j.ejphar.2004.07.070  0.68
2004 Sobrado M, Roda JM, López MG, Egea J, García AG. Galantamine and memantine produce different degrees of neuroprotection in rat hippocampal slices subjected to oxygen-glucose deprivation. Neuroscience Letters. 365: 132-6. PMID 15245794 DOI: 10.1016/j.neulet.2004.04.067  0.84
2004 Calvo-Gómez O, Morales-López J, López MG. Solid-phase microextraction-gas chromatographic-mass spectrometric analysis of garlic oil obtained by hydrodistillation. Journal of Chromatography. A. 1036: 91-3. PMID 15139418  0.68
2004 López MG, Guzmán GR, Dorantes AL. Solid-phase microextraction and gas chromatography-mass spectrometry of volatile compounds from avocado puree after microwave processing. Journal of Chromatography. A. 1036: 87-90. PMID 15139417  0.68
2004 Orozco C, de Los Rios C, Arias E, León R, García AG, Marco JL, Villarroya M, López MG. ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a novel acetylcholinesterase inhibitor with "calcium promotor" and neuroprotective properties. The Journal of Pharmacology and Experimental Therapeutics. 310: 987-94. PMID 15111641 DOI: 10.1124/jpet.104.068189  0.68
2004 Arias E, Alés E, Gabilan NH, Cano-Abad MF, Villarroya M, García AG, López MG. Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors. Neuropharmacology. 46: 103-14. PMID 14654102  0.84
2003 Sobrado M, López MG, Carceller F, García AG, Roda JM. Combined nimodipine and citicoline reduce infarct size, attenuate apoptosis and increase bcl-2 expression after focal cerebral ischemia. Neuroscience. 118: 107-13. PMID 12676142  0.68
2003 Gullo F, Ales E, Rosati B, Lecchi M, Masi A, Guasti L, Cano-Abad MF, Arcangeli A, Lopez MG, Wanke E. ERG K+ channel blockade enhances firing and epinephrine secretion in rat chromaffin cells: the missing link to LQT2-related sudden death? Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 330-2. PMID 12490549 DOI: 10.1096/fj.02-0200fje  0.84
2002 Aguilar-Cisneros BO, López MG, Richling E, Heckel F, Schreier P. Tequila authenticity assessment by headspace SPME-HRGC-IRMS analysis of 13C/12C and 18O/16O ratios of ethanol. Journal of Agricultural and Food Chemistry. 50: 7520-3. PMID 12475264  0.68
2002 Cano-Abad MF, Villarroya M, Garcia AG, Gabilan N, Lopez MG. Contribution of calcium entry through L-type calcium channels to chromaffin cell death. Annals of the New York Academy of Sciences. 971: 171-3. PMID 12438115  0.52
2002 Alés E, Cano-Abad M, García AG, López MG. Different cellular distribution of calbindin D28k: implications for the cytosolic Ca(2+) and exocytotic signals in single bovine and mouse chromaffin cells. Annals of the New York Academy of Sciences. 971: 168-70. PMID 12438114  0.68
2002 Englebienne P, López MG, Cortón E, Viale AA. Use of a CO2 electrode to monitor fermentations that use xenobiotic compounds as source of carbon. Revista Argentina De MicrobiologíA. 34: 72-6. PMID 12180260  0.68
2002 Macías-Rodríguez L, Quero E, López MG. Carbohydrate differences in strawberry crowns and fruit (Fragaria x ananassa) during plant development. Journal of Agricultural and Food Chemistry. 50: 3317-21. PMID 12010004  0.68
2002 Mancilla-Margalli NA, López MG. Generation of Maillard compounds from inulin during the thermal processing of Agave tequilana Weber Var. azul. Journal of Agricultural and Food Chemistry. 50: 806-12. PMID 11829648  0.68
2002 Herrero CJ, Alés E, Pintado AJ, López MG, García-Palomero E, Mahata SK, O'Connor DT, García AG, Montiel C. Modulatory mechanism of the endogenous peptide catestatin on neuronal nicotinic acetylcholine receptors and exocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 377-88. PMID 11784782  0.68
2002 Aguilar-Miranda ED, López MG, Escamilla-Santana C, Barba de la Rosa AP. Characteristics of maize flour tortilla supplemented with ground Tenebrio molitor larvae. Journal of Agricultural and Food Chemistry. 50: 192-5. PMID 11754566  0.68
2001 Cano-Abad MF, Villarroya M, García AG, Gabilan NH, López MG. Calcium entry through L-type calcium channels causes mitochondrial disruption and chromaffin cell death. The Journal of Biological Chemistry. 276: 39695-704. PMID 11500491 DOI: 10.1074/jbc.M102334200  0.84
2001 Bautista-Garfias CR, Ixta-Rodríguez O, Martínez-Gómez F, López MG, Aguilar-Figueroa BR. Effect of viable or dead Lactobacillus casei organisms administered orally to mice on resistance against Trichinella spiralis infection. Parasite (Paris, France). 8: S226-8. PMID 11484363  0.68
2001 Ruiz-Nuño A, Villarroya M, Cano-Abad M, Rosado A, Balfagón G, López MG, García AG. Mechanisms of blockade by the novel migraine prophylactic agent, dotarizine, of various brain and peripheral vessel contractility. European Journal of Pharmacology. 411: 289-99. PMID 11164387  0.68
2000 Ales E, Gabilan NH, Cano-Abad MF, Garcia AG, Lopez MG. The sea anemone toxin Bc2 induces continuous or transient exocytosis, in the presence of sustained levels of high cytosolic Ca2+ in chromaffin cells. The Journal of Biological Chemistry. 275: 37488-95. PMID 10980205 DOI: 10.1074/jbc.M007388200  0.52
2000 Cano-Abad MF, García AG, Sánchez-García P, López MG. Ba(2+)-induced chromaffin cell death: cytoprotection by Ca(2+) channel antagonists. European Journal of Pharmacology. 402: 19-29. PMID 10940353  0.84
2000 Vázquez-López F, Cuesta CA, López MG, Oliva NP. The 21st century macule is not the Willan but the Plenck macule. Archives of Dermatology. 136: 674. PMID 10815869  0.68
1999 Villarroya M, Herrero CJ, Ruíz-Nuño A, de Pascual R, del Valle M, Michelena P, Grau M, Carrasco E, López MG, García AG. PF9404C, a new slow NO donor with beta receptor blocking properties. British Journal of Pharmacology. 128: 1713-22. PMID 10588927 DOI: 10.1038/sj.bjp.0702992  0.68
1999 López MG, Sánchez-Mendoza IR, Ochoa-Alejo N. Compartive study of volatile components and fatty acids of plants and in vitro cultures of parsley (Petroselinum crispum (Mill) nym ex hill). Journal of Agricultural and Food Chemistry. 47: 3292-6. PMID 10552648  0.68
1999 Villarroya M, Olivares R, Ruíz A, Cano-Abad MF, de Pascual R, Lomax RB, López MG, Mayorgas I, Gandía L, García AG. Voltage inactivation of Ca2+ entry and secretion associated with N- and P/Q-type but not L-type Ca2+ channels of bovine chromaffin cells. The Journal of Physiology. 516: 421-32. PMID 10087342  0.84
1999 Villarroya M, López MG, Cano-Abad MF, García AG. Measurement of Ca2+ entry using 45Ca2+. Methods in Molecular Biology (Clifton, N.J.). 114: 137-47. PMID 10081014 DOI: 10.1385/1-59259-250-3:137  0.84
1998 López MG, Montiel C, Herrero CJ, García-Palomero E, Mayorgas I, Hernández-Guijo JM, Villarroya M, Olivares R, Gandía L, McIntosh JM, Olivera BM, García AG. Unmasking the functions of the chromaffin cell alpha7 nicotinic receptor by using short pulses of acetylcholine and selective blockers. Proceedings of the National Academy of Sciences of the United States of America. 95: 14184-9. PMID 9826675  0.68
1998 Cano-Abad MF, López MG, Hernández-Guijo JM, Zapater P, Gandía L, Sánchez-García P, García AG. Effects of the neuroprotectant lubeluzole on the cytotoxic actions of veratridine, barium, ouabain and 6-hydroxydopamine in chromaffin cells. British Journal of Pharmacology. 124: 1187-96. PMID 9720790 DOI: 10.1038/sj.bjp.0701955  0.84
1998 Fernández N, García JL, López MG, García AG, Diéguez G. PCA50941, a new 1,4-dihydropyridine, reverses endothelin-induced cardiogenic shock in the anesthetized goat. Life Sciences. 62: 1933-42. PMID 9619842  0.68
1998 Conceicao IM, Lebrun I, Cano-Abad M, Gandia L, Hernandez-Guijo JM, Lopez MG, Villarroya M, Jurkiewicz A, Garcia AG. Synergism between toxin-gamma from Brazilian scorpion Tityus serrulatus and veratridine in chromaffin cells. The American Journal of Physiology. 274: C1745-54. PMID 9611141  0.48
1997 Michelena P, de la Fuente MT, Vega T, Lara B, López MG, Gandía L, García AG. Drastic facilitation by alpha-latrotoxin of bovine chromaffin cell exocytosis without measurable enhancement of Ca2+ entry or [Ca2+]i. The Journal of Physiology. 502: 481-96. PMID 9279802  0.68
1997 Lara B, Gandía L, Torres A, Olivares R, Martínez-Sierra R, García AG, López MG. 'Wide-spectrum Ca2+ channel antagonists': lipophilicity, inhibition, and recovery of secretion in chromaffin cells. European Journal of Pharmacology. 325: 109-19. PMID 9151946  0.68
1997 Lara B, López MG, Villarroya M, Gandía L, Cleeman L, Morad M, García AG. A caffeine-sensitive Ca2+ store modulates K+-evoked secretion in chromaffin cells. The American Journal of Physiology. 272: C1211-21. PMID 9142846  0.84
1997 Villarroya M, De la Fuente MT, López MG, Gandía L, García AG. Distinct effects of omega-toxins and various groups of Ca(2+)-entry inhibitors on nicotinic acetylcholine receptor and Ca2+ channels of chromaffin cells. European Journal of Pharmacology. 320: 249-57. PMID 9059861  0.68
1996 Villarroya M, Gandía L, López MG, García AG, Cueto S, García-Navio JL, Alvarez-Builla J. Synthesis and pharmacology of alkanediguanidinium compounds that block the neuronal nicotinic acetylcholine receptor. Bioorganic & Medicinal Chemistry. 4: 1177-83. PMID 8879538  0.68
1996 Gandía L, López MG, Villarroya M, Gilabert JA, Cárdenas A, García AG, Borges R. Blocking effects of otilonium on Ca2+ channels and secretion in rat chromaffin cells. European Journal of Pharmacology. 298: 199-205. PMID 8867109 DOI: 10.1016/0014-2999(95)00808-X  0.84
1996 Gandía L, Villarroya M, Lara B, Olmos V, Gilabert JA, López MG, Martínez-Sierra R, Borges R, García AG. Otilonium: a potent blocker of neuronal nicotinic ACh receptors in bovine chromaffin cells. British Journal of Pharmacology. 117: 463-470. PMID 8821535  0.84
1995 Uceda G, Colombo JA, Michelena P, López MG, García AG. Rat striatal astroglia induce morphological and neurochemical changes in adult bovine, adrenergic-enriched adrenal chromaffin cells in vitro. Restorative Neurology and Neuroscience. 8: 129-36. PMID 21551895 DOI: 10.3233/RNN-1995-8303  0.84
1995 Michelena P, Vega T, Montiel C, López MG, García-Perez LE, Gandía L, Garc-ia AG. Effects of tyramine and calcium on the kinetics of secretion in intact and electroporated chromaffin cells superfused at high speed. PflüGers Archiv : European Journal of Physiology. 431: 283-96. PMID 9026790  0.68
1995 Villarroya M, Gandía L, Lara B, Albillos A, López MG, García AG. Dotarizine versus flunarizine as calcium antagonists in chromaffin cells. British Journal of Pharmacology. 114: 369-76. PMID 7881736  0.68
1995 Maroto R, López MG, del Valle M, Naranjo JR, Mellström B, García AG. Expression of the bovine striatal D2 receptor, but not the D1 receptor, in bovine adrenal medulla. Molecular Pharmacology. 47: 40-50. PMID 7838132  0.68
1995 López MG, Artalejo AR, García AG, Neher E, García-Sancho J. Veratridine-induced oscillations of cytosolic calcium and membrane potential in bovine chromaffin cells. The Journal of Physiology. 482: 15-27. PMID 7730979  0.84
1995 Abad F, Maroto R, López MG, Sánchez-García P, García AG. Pharmacological protection against the cytotoxicity induced by 6-hydroxydopamine and H2O2 in chromaffin cells. European Journal of Pharmacology. 293: 55-64. PMID 7672008  0.68
1995 Montiel C, López MG, Sánchez-García P, Maroto R, Zapater P, García AG. Contribution of SK and BK channels in the control of catecholamine release by electrical stimulation of the cat adrenal gland. The Journal of Physiology. 486: 427-37. PMID 7473208  0.68
1994 Uceda G, Artalejo AR, de la Fuente MT, López MG, Albillos A, Michelena P, García AG, Montiel C. Modulation by L-type Ca2+ channels and apamin-sensitive K+ channels of muscarinic responses in cat chromaffin cells. The American Journal of Physiology. 266: C1432-9. PMID 8203505  0.68
1994 López MG, Albillos A, de la Fuente MT, Borges R, Gandía L, Carbone E, García AG, Artalejo AR. Localized L-type calcium channels control exocytosis in cat chromaffin cells. PflüGers Archiv : European Journal of Physiology. 427: 348-54. PMID 8072856  0.68
1994 López MG, Villarroya M, Lara B, Martínez Sierra R, Albillos A, García AG, Gandía L. Q- and L-type Ca2+ channels dominate the control of secretion in bovine chromaffin cells. Febs Letters. 349: 331-7. PMID 8050592 DOI: 10.1016/0014-5793(94)00696-2  0.84
1994 Salas E, López MG, Villarroya M, Sánchez-García P, De Pascual R, Dixon WR, García AG. Endothelium-independent relaxation by 17-alpha-estradiol of pig coronary arteries. European Journal of Pharmacology. 258: 47-55. PMID 7925599  0.68
1994 Maroto R, De la Fuente MT, Artalejo AR, Abad F, López MG, García-Sancho J, García AG. Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ oscillations induced by veratridine. European Journal of Pharmacology. 270: 331-9. PMID 7805782  0.68
1994 Albillos A, Artalejo AR, López MG, Gandía L, García AG, Carbone E. Calcium channel subtypes in cat chromaffin cells. The Journal of Physiology. 477: 197-213. PMID 7523660  0.68
1993 Garcez-Do-Carmo L, Albillos A, Artalejo AR, de la Fuente MT, López MG, Gandía L, Michelena P, García AG. R56865 inhibits catecholamine release from bovine chromaffin cells by blocking calcium channels. British Journal of Pharmacology. 110: 1149-55. PMID 8298803  0.68
1993 von Rüden L, García AG, López MG. The mechanism of Ba(2+)-induced exocytosis from single chromaffin cells. Febs Letters. 336: 48-52. PMID 8262215  0.68
1993 Jiménez RR, López MG, Sancho C, Maroto R, García AG. A component of the catecholamine secretory response in the bovine adrenal gland is resistant to dihydropyridines and omega-conotoxin. Biochemical and Biophysical Research Communications. 191: 1278-83. PMID 7682066 DOI: 10.1006/bbrc.1993.1355  0.68
1993 López MG, Fonteríz RI, Gandía L, de la Fuente M, Villarroya M, García-Sancho J, García AG. The nicotinic acetylcholine receptor of the bovine chromaffin cell, a new target for dihydropyridines. European Journal of Pharmacology. 247: 199-207. PMID 7506660  0.68
1993 Priego J, González-Morales MA, Cillero FJ, Villarroya M, Sunkel C, de Casa-Juana MF, López MG, Artalejo CR, de Pascual R, García AG. PCA 50941, a novel Ca2+ channel agonist. European Journal of Pharmacology. 243: 25-34. PMID 7504630  0.68
1992 Abad F, Garrido B, López MG, García AG. The source of calcium for muscarinic-mediated catecholamine release from cat adrenals. The Journal of Physiology. 445: 725-40. PMID 1501152  0.68
1992 García MC, López MG, García AG, Sánchez Crespo M. Muscarinic acetylcholine receptor enhances phosphatidylcholine hydrolysis via phospholipase D in bovine chromaffin cells in culture. Journal of Neurochemistry. 59: 2244-50. PMID 1431905  0.68
1992 Sunkel CE, Fau de Casa-Juana M, Santos L, García AG, Artalejo CR, Villarroya M, González-Morales MA, López MG, Cillero J, Alonso S. Synthesis of 3-[(2,3-dihydro-1,1,3-trioxo-1,2-benzisothiazol-2-yl)alkyl] 1,4-dihydropyridine-3,5-dicarboxylate derivatives as calcium channel modulators. Journal of Medicinal Chemistry. 35: 2407-14. PMID 1377748  0.84
1992 López MG, Shukla R, García AG, Wakade AR. A dihydropyridine-resistant component in the rat adrenal secretory response to splanchnic nerve stimulation. Journal of Neurochemistry. 58: 2139-44. PMID 1374118  0.68
1992 Fonteriz RI, Garcia-Sancho J, Gandia L, Lopez MG, Garcia AG. Permeation and inactivation by calcium and manganese of bovine adrenal chromaffin cell calcium channels. The American Journal of Physiology. 263: C818-24. PMID 1329546  0.48
1992 Villalobos C, Fonteriz R, López MG, García AG, García-Sancho J. Inhibition of voltage-gated Ca2+ entry into GH3 and chromaffin cells by imidazole antimycotics and other cytochrome P450 blockers. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 6: 2742-7. PMID 1319362  0.68
1992 Uceda G, Artalejo AR, López MG, Abad F, Neher E, García AG. Ca(2+)-activated K+ channels modulate muscarinic secretion in cat chromaffin cells. The Journal of Physiology. 454: 213-30. PMID 1282156  0.84
1991 López MG, Abad F, Sancho C, de Pascual R, Borges R, Maroto R, Dixon W, Garcia AG. Membrane-mediated effects of the steroid 17-alpha-estradiol on adrenal catecholamine release. The Journal of Pharmacology and Experimental Therapeutics. 259: 279-85. PMID 1920120  0.68
1991 Fonteríz RI, López MG, García-Sancho J, García AG. Alamethicin channel permeation by Ca2+, Mn2+ and Ni2+ in bovine chromaffin cells. Febs Letters. 283: 89-92. PMID 1709883  0.68
1991 López MG, Michelena P, Gandía L, García AG. (+)-isradipine but not (-)-Bay-K-8644 exhibits voltage-dependent effects on cat adrenal catecholamine release. British Journal of Pharmacology. 102: 289-96. PMID 1707711  0.68
1991 Gandía L, Casado LF, López MG, García AG. Separation of two pathways for calcium entry into chromaffin cells. British Journal of Pharmacology. 103: 1073-8. PMID 1652335  0.68
1990 Moro MA, López MG, Gandía L, Michelena P, García AG. Separation and culture of living adrenaline- and noradrenaline-containing cells from bovine adrenal medullae. Analytical Biochemistry. 185: 243-8. PMID 2339781  0.68
1990 Gandía L, Michelena P, de Pascual R, López MG, García AG. Different sensitivities to dihydropyridines of catecholamine release from cat and ox adrenals. Neuroreport. 1: 119-22. PMID 1717038  0.68
1990 Garrido B, López MG, Moro MA, de Pascual R, García AG. Voltage-dependent inactivation of catecholamine secretion evoked by brief calcium pulses in the cat adrenal medulla. The Journal of Physiology. 428: 615-37. PMID 1700112  0.68
1989 López MG, Moro MA, Castillo CF, Artalejo CR, García AG. Variable, voltage-dependent, blocking effects of nitrendipine, verapamil, diltiazem, cinnarizine and cadmium on adrenomedullary secretion. British Journal of Pharmacology. 96: 725-31. PMID 2720300  0.84
1989 Castillo CJ, Fonteríz RI, López MG, Rosenheck K, García AG. (+)-PN200-110 and ouabain binding sites in purified bovine adrenomedullary plasma membranes and chromaffin cells. Journal of Neurochemistry. 53: 1442-9. PMID 2529351  0.68
1988 Artalejo CR, López MG, Moro MA, Castillo CF, de Pascual R, García AG. Voltage-dependence of nitrendipine provides direct evidence for dihydropyridine receptor coupling to calcium channels in intact cat adrenals. Biochemical and Biophysical Research Communications. 153: 912-8. PMID 2455516 DOI: 10.1016/S0006-291X(88)81314-7  0.84
1987 Gandía L, López MG, Fonteríz RI, Artalejo CR, García AG. Relative sensitivities of chromaffin cell calcium channels to organic and inorganic calcium antagonists. Neuroscience Letters. 77: 333-8. PMID 2441329  0.68
1987 Fonteriz RI, Gandia L, Lopez MG, Artalejo CR, García AG. Dihydropyridine chirality at the chromaffin cell calcium channel. Brain Research. 408: 359-62. PMID 2439171  0.44
1966 Mata LA, López MG. [Electrocardiographic changes in the P wave in interventricular communication and patent ductus arteriosus]. Archivos Del Instituto De Cardiología De MéXico. 36: 414-28. PMID 5917989  0.68
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