H. Gobind Khorana - Publications

Affiliations: 
Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
molecular mechanisms of visual transduction
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1968/khorana-bio.html

191 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Ou WB, Yi T, Kim JM, Khorana HG. The roles of transmembrane domain helix-III during rhodopsin photoactivation. Plos One. 6: e17398. PMID 21364764 DOI: 10.1371/journal.pone.0017398  0.96
2009 Ahuja S, Crocker E, Eilers M, Hornak V, Hirshfeld A, Ziliox M, Syrett N, Reeves PJ, Khorana HG, Sheves M, Smith SO. Location of the retinal chromophore in the activated state of rhodopsin*. The Journal of Biological Chemistry. 284: 10190-201. PMID 19176531 DOI: 10.1074/jbc.M805725200  1
2008 Takayama H, Chelikani P, Reeves PJ, Zhang S, Khorana HG. High-level expression, single-step immunoaffinity purification and characterization of human tetraspanin membrane protein CD81. Plos One. 3: e2314. PMID 18523555 DOI: 10.1371/journal.pone.0002314  0.48
2007 McKibbin C, Farmer NA, Jeans C, Reeves PJ, Khorana HG, Wallace BA, Edwards PC, Villa C, Booth PJ. Opsin stability and folding: modulation by phospholipid bicelles. Journal of Molecular Biology. 374: 1319-32. PMID 17996895 DOI: 10.1016/j.jmb.2007.10.018  1
2007 McKibbin C, Toye AM, Reeves PJ, Khorana HG, Edwards PC, Villa C, Booth PJ. Opsin stability and folding: the role of Cys185 and abnormal disulfide bond formation in the intradiscal domain. Journal of Molecular Biology. 374: 1309-18. PMID 17988684 DOI: 10.1016/j.jmb.2007.10.013  1
2007 Chelikani P, Hornak V, Eilers M, Reeves PJ, Smith SO, RajBhandary UL, Khorana HG. Role of group-conserved residues in the helical core of beta2-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 7027-32. PMID 17438264 DOI: 10.1073/pnas.0702024104  1
2006 Zhao X, Nagai Y, Reeves PJ, Kiley P, Khorana HG, Zhang S. Designer short peptide surfactants stabilize G protein-coupled receptor bovine rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 103: 17707-12. PMID 17098868 DOI: 10.1073/pnas.0607167103  0.48
2006 Chelikani P, Reeves PJ, Rajbhandary UL, Khorana HG. The synthesis and high-level expression of a beta2-adrenergic receptor gene in a tetracycline-inducible stable mammalian cell line. Protein Science : a Publication of the Protein Society. 15: 1433-40. PMID 16731977 DOI: 10.1110/ps.062080006  1
2006 Kota P, Reeves PJ, Rajbhandary UL, Khorana HG. Opsin is present as dimers in COS1 cells: identification of amino acids at the dimeric interface. Proceedings of the National Academy of Sciences of the United States of America. 103: 3054-9. PMID 16492774 DOI: 10.1073/pnas.0510982103  1
2005 Patel AB, Crocker E, Reeves PJ, Getmanova EV, Eilers M, Khorana HG, Smith SO. Changes in interhelical hydrogen bonding upon rhodopsin activation. Journal of Molecular Biology. 347: 803-12. PMID 15769471 DOI: 10.1016/j.jmb.2005.01.069  0.48
2005 Kim JM, Hwa J, Garriga P, Reeves PJ, RajBhandary UL, Khorana HG. Light-driven activation of beta 2-adrenergic receptor signaling by a chimeric rhodopsin containing the beta 2-adrenergic receptor cytoplasmic loops. Biochemistry. 44: 2284-92. PMID 15709741 DOI: 10.1021/bi048328i  1
2004 Kim JM, Altenbach C, Kono M, Oprian DD, Hubbell WL, Khorana HG. Structural origins of constitutive activation in rhodopsin: Role of the K296/E113 salt bridge. Proceedings of the National Academy of Sciences of the United States of America. 101: 12508-13. PMID 15306683 DOI: 10.1073/pnas.0404519101  1
2004 Rader AJ, Anderson G, Isin B, Khorana HG, Bahar I, Klein-Seetharaman J. Identification of core amino acids stabilizing rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 101: 7246-51. PMID 15123809 DOI: 10.1073/pnas.0401429101  1
2004 Crocker E, Patel AB, Eilers M, Jayaraman S, Getmanova E, Reeves PJ, Ziliox M, Khorana HG, Sheves M, Smith SO. Dipolar assisted rotational resonance NMR of tryptophan and tyrosine in rhodopsin. Journal of Biomolecular Nmr. 29: 11-20. PMID 15017136 DOI: 10.1023/B:JNMR.0000019521.79321.3c  1
2004 Klein-Seetharaman J, Yanamala NV, Javeed F, Reeves PJ, Getmanova EV, Loewen MC, Schwalbe H, Khorana HG. Differential dynamics in the G protein-coupled receptor rhodopsin revealed by solution NMR. Proceedings of the National Academy of Sciences of the United States of America. 101: 3409-13. PMID 14990789 DOI: 10.1073/pnas.0308713101  1
2004 Getmanova E, Patel AB, Klein-Seetharaman J, Loewen MC, Reeves PJ, Friedman N, Sheves M, Smith SO, Khorana HG. NMR spectroscopy of phosphorylated wild-type rhodopsin: mobility of the phosphorylated C-terminus of rhodopsin in the dark and upon light activation. Biochemistry. 43: 1126-33. PMID 14744159 DOI: 10.1021/bi030120u  1
2003 Stojanovic A, Hwang I, Khorana HG, Hwa J. Retinitis pigmentosa rhodopsin mutations L125R and A164V perturb critical interhelical interactions: new insights through compensatory mutations and crystal structure analysis. The Journal of Biological Chemistry. 278: 39020-8. PMID 12871954 DOI: 10.1074/jbc.M303625200  0.32
2003 Hubbell WL, Altenbach C, Hubbell CM, Khorana HG. Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking. Advances in Protein Chemistry. 63: 243-90. PMID 12629973 DOI: 10.1016/S0065-3233(03)63010-X  1
2002 Reeves PJ, Callewaert N, Contreras R, Khorana HG. Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line. Proceedings of the National Academy of Sciences of the United States of America. 99: 13419-24. PMID 12370423 DOI: 10.1073/pnas.212519299  0.48
2002 Reeves PJ, Kim JM, Khorana HG. Structure and function in rhodopsin: a tetracycline-inducible system in stable mammalian cell lines for high-level expression of opsin mutants. Proceedings of the National Academy of Sciences of the United States of America. 99: 13413-8. PMID 12370422 DOI: 10.1073/pnas.212519199  0.96
2002 Niu L, Kim JM, Khorana HG. Structure and function in rhodopsin: asymmetric reconstitution of rhodopsin in liposomes. Proceedings of the National Academy of Sciences of the United States of America. 99: 13409-12. PMID 12370420 DOI: 10.1073/pnas.212518899  1
2002 Klein-Seetharaman J, Reeves PJ, Loewen MC, Getmanova EV, Chung J, Schwalbe H, Wright PE, Khorana HG. Solution NMR spectroscopy of [alpha -15N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence. Proceedings of the National Academy of Sciences of the United States of America. 99: 3452-7. PMID 11904408 DOI: 10.1073/pnas.052713999  1
2002 Eilers M, Ying W, Reeves PJ, Khorana HG, Smith SO. Magic angle spinning nuclear magnetic resonance of isotopically labeled rhodopsin. Methods in Enzymology. 343: 212-22. PMID 11675791 DOI: 10.1016/S0076-6879(02)43137-0  0.48
2002 Khorana HG, Reeves PJ, Kim JM. Structure and mechanism in G protein-coupled receptors Pharmaceutical News. 9: 287-294. DOI: 10.1080/10718940216625  0.96
2001 Altenbach C, Klein-Seetharaman J, Cai K, Khorana HG, Hubbell WL. Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 316 in helix 8 and residues in the sequence 60-75, covering the cytoplasmic end of helices TM1 and TM2 and their connection loop CL1. Biochemistry. 40: 15493-500. PMID 11747424 DOI: 10.1021/bi011545o  1
2001 Altenbach C, Cai K, Klein-Seetharaman J, Khorana HG, Hubbell WL. Structure and function in rhodopsin: mapping light-dependent changes in distance between residue 65 in helix TM1 and residues in the sequence 306-319 at the cytoplasmic end of helix TM7 and in helix H8. Biochemistry. 40: 15483-92. PMID 11747423 DOI: 10.1021/bi011546g  1
2001 Cai K, Klein-Seetharaman J, Altenbach C, Hubbell WL, Khorana HG. Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between cysteine pairs engineered in cytoplasmic loops 1, 3, and 4. Biochemistry. 40: 12479-85. PMID 11601971 DOI: 10.1021/bi010747h  1
2001 Klein-Seetharaman J, Hwa J, Cai K, Altenbach C, Hubbell WL, Khorana HG. Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between Cys316 and engineered cysteines in cytoplasmic loop 1. Biochemistry. 40: 12472-8. PMID 11601970 DOI: 10.1021/bi010746p  1
2001 Allen SJ, Kim JM, Khorana HG, Lu H, Booth PJ. Structure and function in bacteriorhodopsin: the effect of the interhelical loops on the protein folding kinetics. Journal of Molecular Biology. 308: 423-35. PMID 11327777 DOI: 10.1006/jmbi.2001.4604  0.96
2001 Kim JM, Booth PJ, Allen SJ, Khorana HG. Structure and function in bacteriorhodopsin: the role of the interhelical loops in the folding and stability of bacteriorhodopsin. Journal of Molecular Biology. 308: 409-22. PMID 11327776 DOI: 10.1006/jmbi.2001.4603  0.96
2001 Loewen MC, Klein-Seetharaman J, Getmanova EV, Reeves PJ, Schwalbe H, Khorana HG. Solution 19F nuclear Overhauser effects in structural studies of the cytoplasmic domain of mammalian rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 98: 4888-92. PMID 11320239 DOI: 10.1073/pnas.051633098  1
2001 Hwa J, Klein-Seetharaman J, Khorana HG. Structure and function in rhodopsin: Mass spectrometric identification of the abnormal intradiscal disulfide bond in misfolded retinitis pigmentosa mutants. Proceedings of the National Academy of Sciences of the United States of America. 98: 4872-6. PMID 11320236 DOI: 10.1073/pnas.061632798  0.32
2000 Alexiev U, Mollaaghababa R, Khorana HG, Heyn MP. Evidence for long range allosteric interactions between the extracellular and cytoplasmic parts of bacteriorhodopsin from the mutant R82A and its second site revertant R82A/G231C. The Journal of Biological Chemistry. 275: 13431-40. PMID 10788455 DOI: 10.1074/jbc.275.18.13431  0.72
2000 Cha K, Reeves PJ, Khorana HG. Structure and function in rhodopsin: destabilization of rhodopsin by the binding of an antibody at the N-terminal segment provides support for involvement of the latter in an intradiscal tertiary structure. Proceedings of the National Academy of Sciences of the United States of America. 97: 3016-21. PMID 10737783  1
2000 Bruel C, Cha K, Niu L, Reeves PJ, Khorana HG. Rhodopsin kinase: two mAbs binding near the carboxyl terminus cause time-dependent inactivation. Proceedings of the National Academy of Sciences of the United States of America. 97: 3010-5. PMID 10737782 DOI: 10.1073/pnas.97.7.3010  1
2000 Bruel C, Cha K, Reeves PJ, Getmanova E, Khorana HG. Rhodopsin kinase: expression in mammalian cells and a two-step purification. Proceedings of the National Academy of Sciences of the United States of America. 97: 3004-9. PMID 10737781 DOI: 10.1073/pnas.97.7.3004  0.48
2000 Mollaaghababa R, Steinhoff HJ, Hubbell WL, Khorana HG. Time-resolved site-directed spin-labeling studies of bacteriorhodopsin: loop-specific conformational changes in M. Biochemistry. 39: 1120-7. PMID 10653658 DOI: 10.1021/bi991963h  1
1999 Reeves PJ, Klein-Seetharaman J, Getmanova EV, Eilers M, Loewen MC, Smith SO, Khorana HG. Expression and purification of rhodopsin and its mutants from stable mammalian cell lines: application to NMR studies. Biochemical Society Transactions. 27: 950-5. PMID 10830134  1
1999 Klein-Seetharaman J, Getmanova EV, Loewen MC, Reeves PJ, Khorana HG. NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR. Proceedings of the National Academy of Sciences of the United States of America. 96: 13744-9. PMID 10570143 DOI: 10.1073/pnas.96.24.13744  1
1999 Cai K, Klein-Seetharaman J, Hwa J, Hubbell WL, Khorana HG. Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase. Biochemistry. 38: 12893-8. PMID 10504260 DOI: 10.1021/bi9912443  1
1999 Hwa J, Reeves PJ, Klein-Seetharaman J, Davidson F, Khorana HG. Structure and function in rhodopsin: further elucidation of the role of the intradiscal cysteines, Cys-110, -185, and -187, in rhodopsin folding and function. Proceedings of the National Academy of Sciences of the United States of America. 96: 1932-5. PMID 10051572 DOI: 10.1073/pnas.96.5.1932  0.48
1999 Reeves PJ, Hwa J, Khorana HG. Structure and function in rhodopsin: kinetic studies of retinal binding to purified opsin mutants in defined phospholipid-detergent mixtures serve as probes of the retinal binding pocket. Proceedings of the National Academy of Sciences of the United States of America. 96: 1927-31. PMID 10051571 DOI: 10.1073/pnas.96.5.1927  0.48
1999 Eilers M, Reeves PJ, Ying W, Khorana HG, Smith SO. Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: expression of 15N-lysine- and 13C-glycine-labeled opsin in a stable cell line. Proceedings of the National Academy of Sciences of the United States of America. 96: 487-92. PMID 9892660 DOI: 10.1073/pnas.96.2.487  0.48
1998 Behrens W, Alexiev U, Mollaaghababa R, Khorana HG, Heyn MP. Structure of the interhelical loops and carboxyl terminus of bacteriorhodopsin by X-ray diffraction using site-directed heavy-atom labeling. Biochemistry. 37: 10411-9. PMID 9671510 DOI: 10.1021/bi971735s  1
1997 Kim JM, Altenbach C, Thurmond RL, Khorana HG, Hubbell WL. Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state. Proceedings of the National Academy of Sciences of the United States of America. 94: 14273-8. PMID 9405602 DOI: 10.1073/pnas.94.26.14273  1
1997 Cai K, Langen R, Hubbell WL, Khorana HG. Structure and function in rhodopsin: topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops. Proceedings of the National Academy of Sciences of the United States of America. 94: 14267-72. PMID 9405601 DOI: 10.1073/pnas.94.26.14267  1
1997 Cha K, Bruel C, Inglese J, Khorana HG. Rhodopsin kinase: expression in baculovirus-infected insect cells, and characterization of post-translational modifications. Proceedings of the National Academy of Sciences of the United States of America. 94: 10577-82. PMID 9380677 DOI: 10.1073/pnas.94.20.10577  1
1997 Hwa J, Garriga P, Liu X, Khorana HG. Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled. Proceedings of the National Academy of Sciences of the United States of America. 94: 10571-6. PMID 9380676 DOI: 10.1073/pnas.94.20.10571  0.32
1997 Thurmond RL, Creuzenet C, Reeves PJ, Khorana HG. Structure and function in rhodopsin: peptide sequences in the cytoplasmic loops of rhodopsin are intimately involved in interaction with rhodopsin kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 1715-20. PMID 9050844 DOI: 10.1073/pnas.94.5.1715  0.48
1997 Kim JM, Khorana HG. The role of interhelical loops in folding of bacteriorhodopsin: Their replacements by unstructured peptide linkers Faseb Journal. 11: A953.  0.96
1997 Cai K, Khorana HG. Topology of the c-terminal tail and cytoplasmic loops in rhodopsin in dark state and after activation by light Faseb Journal. 11: A921.  1
1997 Reeves PJ, Thurmond RL, Khorana HG. High-level production of rhodopsin and selected mutants using stable mammalian cell lines Faseb Journal. 11: A1332.  0.48
1996 Reeves PJ, Thurmond RL, Khorana HG. Structure and function in rhodopsin: high level expression of a synthetic bovine opsin gene and its mutants in stable mammalian cell lines. Proceedings of the National Academy of Sciences of the United States of America. 93: 11487-92. PMID 8876162 DOI: 10.1073/pnas.93.21.11487  0.48
1996 Mollaaghababa R, Davidson FF, Kaiser C, Khorana HG. Structure and function in rhodopsin: expression of functional mammalian opsin in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 93: 11482-6. PMID 8876161 DOI: 10.1073/pnas.93.21.11482  0.68
1996 Farrens DL, Altenbach C, Yang K, Hubbell WL, Khorana HG. Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. Science (New York, N.Y.). 274: 768-70. PMID 8864113 DOI: 10.1126/science.274.5288.768  1
1996 Garriga P, Liu X, Khorana HG. Structure and function in rhodopsin: correct folding and misfolding in point mutants at and in proximity to the site of the retinitis pigmentosa mutation Leu-125-->Arg in the transmembrane helix C. Proceedings of the National Academy of Sciences of the United States of America. 93: 4560-4. PMID 8643443  0.32
1996 Liu X, Garriga P, Khorana HG. Structure and function in rhodopsin: correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America. 93: 4554-9. PMID 8643442 DOI: 10.1073/pnas.93.10.4554  0.32
1996 Cha K, Inglese J, Khorana HG. Expression of rhodopsin kinase (RK) in baculovirus infected cells, purification and characterization Faseb Journal. 10: A1119.  1
1995 Moltke S, Krebs MP, Mollaaghababa R, Khorana HG, Heyn MP. Intramolecular charge transfer in the bacteriorhodopsin mutants Asp85-->Asn and Asp212-->Asn: effects of pH and anions. Biophysical Journal. 69: 2074-83. PMID 8580351 DOI: 10.1016/S0006-3495(95)80078-0  1
1995 Dickopf S, Alexiev U, Krebs MP, Otto H, Mollaaghababa R, Khorana HG, Heyn MP. Proton transport by a bacteriorhodopsin mutant, aspartic acid-85-->asparagine, initiated in the unprotonated Schiff base state. Proceedings of the National Academy of Sciences of the United States of America. 92: 11519-23. PMID 8524795 DOI: 10.1073/pnas.92.25.11519  1
1995 Ridge KD, Lu Z, Liu X, Khorana HG. Structure and function in rhodopsin. Separation and characterization of the correctly folded and misfolded opsins produced on expression of an opsin mutant gene containing only the native intradiscal cysteine codons. Biochemistry. 34: 3261-7. PMID 7880821  1
1995 Alexiev U, Mollaaghababa R, Scherrer P, Khorana HG, Heyn MP. Rapid long-range proton diffusion along the surface of the purple membrane and delayed proton transfer into the bulk. Proceedings of the National Academy of Sciences of the United States of America. 92: 372-6. PMID 7831293 DOI: 10.1073/pnas.92.2.372  1
1995 Booth PJ, Flitsch SL, Stern LJ, Greenhalgh DA, Kim PS, Khorana HG. Intermediates in the folding of the membrane protein bacteriorhodopsin. Nature Structural Biology. 2: 139-43. PMID 7749918 DOI: 10.1038/nsb0295-139  1
1995 Steinhoff HJ, Mollaaghababa R, Altenbach C, Khorana HG, Hubbell WL. Site directed spin labeling studies of structure and dynamics in bacteriorhodopsin. Biophysical Chemistry. 56: 89-94. PMID 7662873 DOI: 10.1016/0301-4622(95)00019-T  0.56
1995 Farahbakhsh ZT, Ridge KD, Khorana HG, Hubbell WL. Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study. Biochemistry. 34: 8812-9. PMID 7612622  0.52
1995 Ridge KD, Zhang C, Khorana HG. Mapping of the amino acids in the cytoplasmic loop connecting helices C and D in rhodopsin. Chemical reactivity in the dark state following single cysteine replacements. Biochemistry. 34: 8804-11. PMID 7612621  0.52
1995 Alexiev U, Scherrer P, Marti T, Khorana HG, Heyn MP. Time-resolved surface charge change on the cytoplasmic side of bacteriorhodopsin. Febs Letters. 373: 81-4. PMID 7589439 DOI: 10.1016/0014-5793(95)00985-I  1
1994 Alexiev U, Marti T, Heyn MP, Khorana HG, Scherrer P. Surface charge of bacteriorhodopsin detected with covalently bound pH indicators at selected extracellular and cytoplasmic sites. Biochemistry. 33: 298-306. PMID 8286351  1
1994 Davidson FF, Loewen PC, Khorana HG. Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state. Proceedings of the National Academy of Sciences of the United States of America. 91: 4029-33. PMID 8171030  0.52
1994 Kaushal S, Ridge KD, Khorana HG. Structure and function in rhodopsin: the role of asparagine-linked glycosylation. Proceedings of the National Academy of Sciences of the United States of America. 91: 4024-8. PMID 8171029  1
1994 Altenbach C, Greenhalgh DA, Khorana HG, Hubbell WL. A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 91: 1667-71. PMID 8127863  1
1994 Sonar S, Marti T, Rath P, Fischer W, Coleman M, Nilsson A, Khorana HG, Rothschild KJ. A redirected proton pathway in the bacteriorhodopsin mutant Tyr-57-->Asp. Evidence for proton translocation without Schiff base deprotonation. The Journal of Biological Chemistry. 269: 28851-8. PMID 7961844  1
1994 Alexiev U, Marti T, Heyn MP, Khorana HG, Scherrer P. Covalently bound pH-indicator dyes at selected extracellular or cytoplasmic sites in bacteriorhodopsin. 2. Rotational orientation of helices D and E and kinetic correlation between M formation and proton release in bacteriorhodopsin micelles. Biochemistry. 33: 13693-9. PMID 7947778  0.68
1994 Scherrer P, Alexiev U, Marti T, Khorana HG, Heyn MP. Covalently bound pH-indicator dyes at selected extracellular or cytoplasmic sites in bacteriorhodopsin. 1. Proton migration along the surface of bacteriorhodopsin micelles and its delayed transfer from surface to bulk. Biochemistry. 33: 13684-92. PMID 7947777  0.68
1994 Fischer WB, Sonar S, Marti T, Khorana HG, Rothschild KJ. Detection of a water molecule in the active-site of bacteriorhodopsin: hydrogen bonding changes during the primary photoreaction. Biochemistry. 33: 12757-62. PMID 7947680  0.76
1994 Steinhoff HJ, Mollaaghababa R, Altenbach C, Hideg K, Krebs M, Khorana HG, Hubbell WL. Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin. Science (New York, N.Y.). 266: 105-7. PMID 7939627  1
1994 Sonar S, Lee CP, Coleman M, Patel N, Liu X, Marti T, Khorana HG, RajBhandary UL, Rothschild KJ. Site-directed isotope labelling and FTIR spectroscopy of bacteriorhodopsin. Nature Structural Biology. 1: 512-7. PMID 7664078 DOI: 10.1038/nsb0894-512  1
1993 Krebs MP, Spudich EN, Khorana HG, Spudich JL. Synthesis of a gene for sensory rhodopsin I and its functional expression in Halobacterium halobium. Proceedings of the National Academy of Sciences of the United States of America. 90: 3486-90. PMID 8475097  1
1993 Krebs MP, Mollaaghababa R, Khorana HG. Gene replacement in Halobacterium halobium and expression of bacteriorhodopsin mutants. Proceedings of the National Academy of Sciences of the United States of America. 90: 1987-91. PMID 8446619  1
1993 He Y, Krebs MP, Fischer WB, Khorana HG, Rothschild KJ. FTIR difference spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: detection of a stable O-like species and characterization of its photocycle at low temperature. Biochemistry. 32: 2282-90. PMID 8443171  1
1993 Rath P, Krebs MP, He Y, Khorana HG, Rothschild KJ. Fourier transform Raman spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: formation of a stable O-like species during light adaptation and detection of its transient N-like photoproduct. Biochemistry. 32: 2272-81. PMID 8443170  1
1993 Sonar S, Krebs MP, Khorana HG, Rothschild KJ. Static and time-resolved absorption spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: evidence for an equilibrium between bR570 and an O-like species. Biochemistry. 32: 2263-71. PMID 8443169  1
1993 Karnik SS, Ridge KD, Bhattacharya S, Khorana HG. Palmitoylation of bovine opsin and its cysteine mutants in COS cells. Proceedings of the National Academy of Sciences of the United States of America. 90: 40-4. PMID 8419942  1
1993 Krebs MP, Khorana HG. Mechanism of light-dependent proton translocation by bacteriorhodopsin. Journal of Bacteriology. 175: 1555-60. PMID 8383660  1
1993 Greenhalgh DA, Farrens DL, Subramaniam S, Khorana HG. Hydrophobic amino acids in the retinal-binding pocket of bacteriorhodopsin. The Journal of Biological Chemistry. 268: 20305-11. PMID 8376389  0.56
1993 Zhang YN, el-Sayed MA, Stern LJ, Marti T, Mogi T, Khorana HG. Effects of mutagenetic substitution of prolines on the rate of deprotonation and reprotonation of the Schiff base during the photocycle of bacteriorhodopsin. Photochemistry and Photobiology. 57: 1027-31. PMID 8367532  1
1993 Rath P, Marti T, Sonar S, Khorana HG, Rothschild KJ. Hydrogen bonding interactions with the Schiff base of bacteriorhodopsin. Resonance Raman spectroscopy of the mutants D85N and D85A. The Journal of Biological Chemistry. 268: 17742-9. PMID 8349659  1
1993 Rothschild KJ, Marti T, Sonar S, He YW, Rath P, Fischer W, Khorana HG. Asp96 deprotonation and transmembrane alpha-helical structural changes in bacteriorhodopsin. The Journal of Biological Chemistry. 268: 27046-52. PMID 8262942  1
1993 Krebs MP, Behrens W, Mollaaghababa R, Khorana HG, Heyn MP. X-ray diffraction of a cysteine-containing bacteriorhodopsin mutant and its mercury derivative. Localization of an amino acid residue in the loop of an integral membrane protein. Biochemistry. 32: 12830-4. PMID 8251504 DOI: 10.1021/bi00210a035  1
1993 Resek JF, Farahbakhsh ZT, Hubbell WL, Khorana HG. Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin. Biochemistry. 32: 12025-32. PMID 8218279 DOI: 10.1021/bi00096a012  1
1993 Knox BE, Khorana HG, Nasi E. Light-induced currents in Xenopus oocytes expressing bovine rhodopsin. The Journal of Physiology. 466: 157-72. PMID 7692039 DOI: 10.1113/jphysiol.1993.sp019714  1
1992 Rothschild KJ, He YW, Sonar S, Marti T, Khorana HG. Vibrational spectroscopy of bacteriorhodopsin mutants. Evidence that Thr-46 and Thr-89 form part of a transient network of hydrogen bonds. The Journal of Biological Chemistry. 267: 1615-22. PMID 1730706  1
1992 Franke RR, Sakmar TP, Graham RM, Khorana HG. Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin. The Journal of Biological Chemistry. 267: 14767-74. PMID 1634520  0.96
1992 Bhattacharya S, Ridge KD, Knox BE, Khorana HG. Light-stable rhodopsin. I. A rhodopsin analog reconstituted with a nonisomerizable 11-cis retinal derivative. The Journal of Biological Chemistry. 267: 6763-9. PMID 1551885  1
1992 Bhattacharya S, Marti T, Otto H, Heyn MP, Khorana HG. A bacteriorhodopsin analog reconstituted with a nonisomerizable 13-trans retinal derivative displays light insensitivity. The Journal of Biological Chemistry. 267: 6757-62. PMID 1551884  1
1992 Ridge KD, Bhattacharya S, Nakayama TA, Khorana HG. Light-stable rhodopsin. II. An opsin mutant (TRP-265----Phe) and a retinal analog with a nonisomerizable 11-cis configuration form a photostable chromophore. The Journal of Biological Chemistry. 267: 6770-5. PMID 1532391  1
1992 Marti T, Otto H, Rösselet SJ, Heyn MP, Khorana HG. Consequences of amino acid insertions and/or deletions in transmembrane helix C of bacteriorhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 89: 1219-23. PMID 1531536  1
1992 Marti T, Otto H, Rösselet SJ, Heyn MP, Khorana HG. Anion binding to the Schiff base of the bacteriorhodopsin mutants Asp-85----Asn/Asp-212----Asn and Arg-82----Gln/Asp-85----Asn/Asp-212----Asn. The Journal of Biological Chemistry. 267: 16922-7. PMID 1512233  0.44
1992 Subramaniam S, Greenhalgh DA, Khorana HG. Aspartic acid 85 in bacteriorhodopsin functions both as proton acceptor and negative counterion to the Schiff base. The Journal of Biological Chemistry. 267: 25730-3. PMID 1464589  0.56
1992 Sgaramella V, Khorana HG. A further study of the T4 ligase-catalyzed joining of DNA at base-paired ends. 1972. Biotechnology (Reading, Mass.). 24: 28-37. PMID 1422025  0.64
1992 Greenhalgh DA, Subramaniam S, Alexiev U, Otto H, Heyn MP, Khorana HG. Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin. The Journal of Biological Chemistry. 267: 25734-8. PMID 1361187  1
1992 Lin SW, Sakmar TP, Franke RR, Khorana HG, Mathies RA. Resonance Raman microprobe spectroscopy of rhodopsin mutants: effect of substitutions in the third transmembrane helix. Biochemistry. 31: 5105-11. PMID 1351402  1
1992 Bousché O, Sonar S, Krebs MP, Khorana HG, Rothschild KJ. Time-resolved Fourier transform infrared spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: Asp-96 reprotonates during O formation; Asp-85 and Asp-212 deprotonate during O decay. Photochemistry and Photobiology. 56: 1085-95. PMID 1337213  1
1992 Wu S, Chang Y, el-Sayed MA, Marti T, Mogi T, Khorana HG. Effects of tryptophan mutation on the deprotonation and reprotonation kinetics of the Schiff base during the photocycle of bacteriorhodopsin. Biophysical Journal. 61: 1281-8. PMID 1318094 DOI: 10.1016/S0006-3495(92)81936-7  0.76
1991 Sakmar TP, Franke RR, Khorana HG. The role of the retinylidene Schiff base counterion in rhodopsin in determining wavelength absorbance and Schiff base pKa. Proceedings of the National Academy of Sciences of the United States of America. 88: 3079-83. PMID 2014228  1
1991 Krebs MP, Hauss T, Heyn MP, RajBhandary UL, Khorana HG. Expression of the bacterioopsin gene in Halobacterium halobium using a multicopy plasmid. Proceedings of the National Academy of Sciences of the United States of America. 88: 859-63. PMID 1992477 DOI: 10.1073/pnas.88.3.859  1
1991 Marti T, Rösselet SJ, Otto H, Heyn MP, Khorana HG. The retinylidene Schiff base counterion in bacteriorhodopsin. The Journal of Biological Chemistry. 266: 18674-83. PMID 1917991  1
1991 Lin GC, el-Sayed MA, Marti T, Stern LJ, Mogi T, Khorana HG. Effects of individual genetic substitutions of arginine residues on the deprotonation and reprotonation kinetics of the Schiff base during the bacteriorhodopsin photocycle. Biophysical Journal. 60: 172-8. PMID 1883936 DOI: 10.1016/S0006-3495(91)82040-9  1
1991 Greenhalgh DA, Altenbach C, Hubbell WL, Khorana HG. Locations of Arg-82, Asp-85, and Asp-96 in helix C of bacteriorhodopsin relative to the aqueous boundaries. Proceedings of the National Academy of Sciences of the United States of America. 88: 8626-30. PMID 1656452 DOI: 10.1073/pnas.88.19.8626  1
1991 Subramaniam S, Greenhalgh DA, Rath P, Rothschild KJ, Khorana HG. Replacement of leucine-93 by alanine or threonine slows down the decay of the N and O intermediates in the photocycle of bacteriorhodopsin: implications for proton uptake and 13-cis-retinal----all-trans-retinal reisomerization. Proceedings of the National Academy of Sciences of the United States of America. 88: 6873-7. PMID 1650486  1
1990 Hackett NR, Krebs MP, DasSarma S, Goebel W, RajBhandary UL, Khorana HG. Nucleotide sequence of a high copy number plasmid from Halobacterium strain GRB. Nucleic Acids Research. 18: 3408. PMID 2356134 DOI: 10.1093/nar/18.11.3408  0.96
1990 Jang DJ, el-Sayed MA, Stern LJ, Mogi T, Khorana HG. Effect of genetic modification of tyrosine-185 on the proton pump and the blue-to-purple transition in bacteriorhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 87: 4103-7. PMID 2349220  1
1990 Franke RR, König B, Sakmar TP, Khorana HG, Hofmann KP. Rhodopsin mutants that bind but fail to activate transducin. Science (New York, N.Y.). 250: 123-5. PMID 2218504  1
1990 Du JJ, el-Sayed MA, Stern LJ, Mogi T, Khorana HG. Sensitivity of the retinal circular dichroism of bacteriorhodopsin to the mutagenetic single substitution of amino acids: tyrosine. Febs Letters. 262: 155-8. PMID 2185945 DOI: 10.1016/0014-5793(90)80178-L  1
1990 Krebs MP, RajBhandary UL, Khorana HG. Nucleotide sequence of ISH11, a new Halobacterium halobium insertion element isolated from the plasmid pGRB1. Nucleic Acids Research. 18: 6699. PMID 2174546  0.96
1990 Rothschild KJ, He YW, Mogi T, Marti T, Stern LJ, Khorana HG. Vibrational spectroscopy of bacteriorhodopsin mutants: evidence for the interaction of proline-186 with the retinylidene chromophore. Biochemistry. 29: 5954-60. PMID 2166567  1
1990 Otto H, Marti T, Holz M, Mogi T, Stern LJ, Engel F, Khorana HG, Heyn MP. Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base. Proceedings of the National Academy of Sciences of the United States of America. 87: 1018-22. PMID 2153966  1
1990 Bubis J, Khorana HG. Sites of interaction in the complex between beta- and gamma-subunits of transducin. The Journal of Biological Chemistry. 265: 12995-9. PMID 2115886  1
1989 Rothschild KJ, Gray D, Mogi T, Marti T, Braiman MS, Stern LJ, Khorana HG. Vibrational spectroscopy of bacteriorhodopsin mutants: chromophore isomerization perturbs tryptophan-86. Biochemistry. 28: 7052-9. PMID 2819048  1
1989 Rothschild KJ, Braiman MS, Mogi T, Stern LJ, Khorana HG. Conserved amino acids in F-helix of bacteriorhodopsin form part of a retinal binding pocket. Febs Letters. 250: 448-52. PMID 2753143 DOI: 10.1016/0014-5793(89)80774-4  1
1989 Brouillette CG, McMichens RB, Stern LJ, Khorana HG. Structure and thermal stability of monomeric bacteriorhodopsin in mixed phospholipid/detergent micelles. Proteins. 5: 38-46. PMID 2748571 DOI: 10.1002/prot.340050106  1
1989 Flitsch SL, Khorana HG. Structural studies on transmembrane proteins. 1. Model study using bacteriorhodopsin mutants containing single cysteine residues. Biochemistry. 28: 7800-5. PMID 2692704  0.56
1989 Stern LJ, Ahl PL, Marti T, Mogi T, Duñach M, Berkowitz S, Rothschild KJ, Khorana HG. Substitution of membrane-embedded aspartic acids in bacteriorhodopsin causes specific changes in different steps of the photochemical cycle. Biochemistry. 28: 10035-42. PMID 2575917  1
1989 Ahl PL, Stern LJ, Mogi T, Khorana HG, Rothschild KJ. Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle. Biochemistry. 28: 10028-34. PMID 2575916 DOI: 10.1021/bi00452a022  1
1989 Sakmar TP, Franke RR, Khorana HG. Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 86: 8309-13. PMID 2573063  1
1989 Altenbach C, Flitsch SL, Khorana HG, Hubbell WL. Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines. Biochemistry. 28: 7806-12. PMID 2558712  1
1989 Stern LJ, Khorana HG. Structure-function studies on bacteriorhodopsin. X. Individual substitutions of arginine residues by glutamine affect chromophore formation, photocycle, and proton translocation. The Journal of Biological Chemistry. 264: 14202-8. PMID 2547788  1
1989 Mogi T, Stern LJ, Chao BH, Khorana HG. Structure-function studies on bacteriorhodopsin. VIII. Substitutions of the membrane-embedded prolines 50, 91, and 186: the effects are determined by the substituting amino acids. The Journal of Biological Chemistry. 264: 14192-6. PMID 2547786  1
1988 Mogi T, Stern LJ, Marti T, Chao BH, Khorana HG. Aspartic acid substitutions affect proton translocation by bacteriorhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 85: 4148-52. PMID 3288985  1
1988 Karnik SS, Sakmar TP, Chen HB, Khorana HG. Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 85: 8459-63. PMID 3186735  1
1988 Sakmar TP, Khorana HG. Total synthesis and expression of a gene for the alpha-subunit of bovine rod outer segment guanine nucleotide-binding protein (transducin). Nucleic Acids Research. 16: 6361-72. PMID 3165194  0.92
1988 Franke RR, Sakmar TP, Oprian DD, Khorana HG. A single amino acid substitution in rhodopsin (lysine 248----leucine) prevents activation of transducin. The Journal of Biological Chemistry. 263: 2119-22. PMID 3123487  1
1988 Braiman M, Bubis J, Doi T, Chen HB, Flitsch SL, Franke RR, Gilles-Gonzalez MA, Graham RM, Karnik SS, Khorana HG. Studies on light transduction by bacteriorhodopsin and rhodopsin. Cold Spring Harbor Symposia On Quantitative Biology. 53: 355-64. PMID 3076084  1
1988 Ahl PL, Stern LJ, Düring D, Mogi T, Khorana HG, Rothschild KJ. Effects of amino acid substitutions in the F helix of bacteriorhodopsin. Low temperature ultraviolet/visible difference spectroscopy. The Journal of Biological Chemistry. 263: 13594-601. PMID 3047127  1
1988 Braiman MS, Mogi T, Marti T, Stern LJ, Khorana HG, Rothschild KJ. Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212. Biochemistry. 27: 8516-20. PMID 2851326  1
1988 Braiman MS, Mogi T, Stern LJ, Hackett NR, Chao BH, Khorana HG, Rothschild KJ. Vibrational spectroscopy of bacteriorhodopsin mutants: I. Tyrosine-185 protonates and deprotonates during the photocycle. Proteins. 3: 219-29. PMID 2843849 DOI: 10.1002/prot.340030403  1
1987 Hackett NR, Stern LJ, Chao BH, Kronis KA, Khorana HG. Structure-function studies on bacteriorhodopsin. V. Effects of amino acid substitutions in the putative helix F. The Journal of Biological Chemistry. 262: 9277-84. PMID 3597412  1
1987 Braiman MS, Stern LJ, Chao BH, Khorana HG. Structure-function studies on bacteriorhodopsin. IV. Purification and renaturation of bacterio-opsin polypeptide expressed in Escherichia coli. The Journal of Biological Chemistry. 262: 9271-6. PMID 3298254  1
1987 Mogi T, Stern LJ, Hackett NR, Khorana HG. Bacteriorhodopsin mutants containing single tyrosine to phenylalanine substitutions are all active in proton translocation. Proceedings of the National Academy of Sciences of the United States of America. 84: 5595-9. PMID 3039495  1
1987 Oprian DD, Molday RS, Kaufman RJ, Khorana HG. Expression of a synthetic bovine rhodopsin gene in monkey kidney cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 8874-8. PMID 2962193  1
1986 Ferretti L, Karnik SS, Khorana HG, Nassal M, Oprian DD. Total synthesis of a gene for bovine rhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 83: 599-603. PMID 3456156 DOI: 10.1007/s12045-012-0134-4  1
1985 Yatsunami K, Pandya BV, Oprian DD, Khorana HG. cDNA-derived amino acid sequence of the gamma subunit of GTPase from bovine rod outer segments. Proceedings of the National Academy of Sciences of the United States of America. 82: 1936-40. PMID 2984674  1
1984 Dassarma S, Rajbhandary UL, Khorana HG. Bacterio-opsin mRNA in wild-type and bacterio-opsin-deficient Halobacterium halobium strains. Proceedings of the National Academy of Sciences of the United States of America. 81: 125-9. PMID 16593404  1
1983 DasSarma S, RajBhandary UL, Khorana HG. High-frequency spontaneous mutation in the bacterio-opsin gene in Halobacterium halobium is mediated by transposable elements. Proceedings of the National Academy of Sciences of the United States of America. 80: 2201-5. PMID 6300900  1
1982 Simsek M, DasSarma S, RajBhandary UL, Khorana HG. A transposable element from Halobacterium halobium which inactivates the bacteriorhodopsin gene. Proceedings of the National Academy of Sciences of the United States of America. 79: 7268-72. PMID 6296826  1
1981 Dunn R, McCoy J, Simsek M, Majumdar A, Chang SH, Rajbhandary UL, Khorana HG. The bacteriorhodopsin gene. Proceedings of the National Academy of Sciences of the United States of America. 78: 6744-8. PMID 12049093  1
1981 Chang SH, Majumdar A, Dunn R, Makabe O, RajBhandary UL, Khorana HG, Ohtsuka E, Tanaka T, Taniyama YO, Ikehara M. Bacteriorhodopsin: partial sequence of mRNA provides amino acid sequence in the precursor region. Proceedings of the National Academy of Sciences of the United States of America. 78: 3398-402. PMID 6943548 DOI: 10.1073/pnas.78.6.3398  1
1979 Rosner MR, Verret RC, Khorana HG. The structure of lipopolysaccharide from an Escherichia coli heptose-less mutant. III. Two fatty acyl amidases from Dictyostelium discoideum and their action on lipopolysaccharide derivatives. The Journal of Biological Chemistry. 254: 5926-33. PMID 376523  1
1976 Contreras R, Küpper H, Landy A, Khorana HG. Escherichia coli tyrosine transfer ribonucleic acid genes. Nucleotide sequences of their promoters and of the regions adjoining C-C-A ends. The Journal of Biological Chemistry. 251: 5124-40. PMID 821949  0.36
1976 Agarwal KL, Caruthers MH, Büchi H, van de Sande JH, Khorana HG. Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 6. Synthesis of the deoxyribopolynucleotide segments corresponding to the nucleotide sequence 100-126. The Journal of Biological Chemistry. 251: 624-33. PMID 765331  1
1976 Jay E, Cashion PJ, Fridkin M, Ramamoorthy B, Agarwal KL, Caruthers MH, Khorana HG. Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 5. Synthesis of the deoxyribopolynucleotide segments representing the nucleotide sequence 71-103. The Journal of Biological Chemistry. 251: 609-23. PMID 765330  1
1976 Agarwal KL, Caruthers MH, Fridkin M, Kumar A, van de Sande JH, Khorana HG. Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 4. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence 47-78. The Journal of Biological Chemistry. 251: 599-608. PMID 765329  1
1976 van de Sande JH, Caruthers MH, Kumar A, Khorana HG. Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 2. Chemical synthesis of the deoxypolynucleotide segments corresponding to the nucleotide sequence 1-31. The Journal of Biological Chemistry. 251: 571-86. PMID 765328  1
1976 Khorana HG, Agarwal KL, Besmer P, Büchi H, Caruthers MH, Cashion PJ, Fridkin M, Jay E, Kleppe K, Kleppe R, Kumar A, Loewen PC, Miller RC, Minamoto K, Panet A, et al. Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction. The Journal of Biological Chemistry. 251: 565-70. PMID 765327  1
1976 Kleppe R, Sekiya T, Loewen PC, Kleppe K, Agarwal KL, Büchi H, Besmer P, Caruthers MH, Cashion PJ, Fridkin M, Jay E, Kumar A, Miller RC, Minamoto K, Panet A, ... ... Khorana HG, et al. Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 11. Enzymatic joining to form the total DNA duplex. The Journal of Biological Chemistry. 251: 667-75. PMID 175058  1
1976 Caruthers MH, Kleppe R, Kleppe K, Khorana HG. Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 10. Enzymatic joining of chemically synthesized segments to form the DNA duplex corresponding to the nucleotide sequence 86-126. The Journal of Biological Chemistry. 251: 658-66. PMID 175057  1
1976 Minamoto K, Caruthers MH, Ramamoorthy B, van de Sande JH, Sidorova N, Khorana HG. Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 3. Synthesis of deoxyribopolynucleotide segments corresponding to the nucleotide sequence 27-51. The Journal of Biological Chemistry. 251: 587-98. PMID 175056  1
1975 Powers GJ, Jones RL, Randall GA, Caruthers MH, van de Sande JH, Khorana HG. Optimal strategies for the chemical and enzymatic synthesis of bihelical deoxyribonucleic acids. Journal of the American Chemical Society. 97: 875-84. PMID 1133373  1
1975 Küpper H, Contreras R, Landy A, Khorana HG. Promoter-dependent transcription of tRNAITyr genes using DNA fragments produced by restriction enzymes. Proceedings of the National Academy of Sciences of the United States of America. 72: 4754-8. PMID 1107999  0.36
1973 van de Sande JH, Kleppe K, Khorana HG. Reversal of bacteriophage T4 induced polynucleotide kinase action. Biochemistry. 12: 5050-5. PMID 4366306  1
1973 Panet A, van de Sande JH, Loewen PC, Khorana HG, Raae AJ, Lillehaug JR, Kleppe K. Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase. Biochemistry. 12: 5045-50. PMID 4366077  1
1972 Besmer P, Miller RC, Caruthers MH, Kumar A, Minamoto K, Van de Sande JH, Sidarova N, Khorana HG. Studies on polynucleotides. CXVII. Hybridization of polydeoxynucleotides with tyrosine transfer RNA sequences to the r-strand of phi80psu + 3 DNA. Journal of Molecular Biology. 72: 503-22. PMID 4660319  1
1972 Caruthers MH, Kleppe K, Van de Sande JH, Sgaramella V, Agarwal KL, Büchi H, Gupta NK, Kumar A, Otsuka E, RajBhandary UL, Terao T, Weber H, Yamada T, Khorana HG. CXV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining to form the total DNA duplex. Journal of Molecular Biology. 72: 475-92. PMID 4571087 DOI: 10.1016/0022-2836(72)90158-1  1
1972 Van de Sande JH, Caruthers MH, Sgaramella V, Yamada T, Khorana HG. CXIV. Total synthesis of the structural gene for an alanine transfer RNA from yeast. Enzymic joining of the chemically synthesized segments to form the DNA duplex corresponding to nucleotide sequence 46 to 77. Journal of Molecular Biology. 72: 457-74. PMID 4571086  1
1972 Caruthers MH, Khorana HG. CXI. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of a dodecadeoxynucleotide and a heptadeoxynucleotide corresponding to the nucleotide sequence 66 to 77. Journal of Molecular Biology. 72: 407-26. PMID 4571083  1
1972 Caruthers MH, Van de Sande JH, Khorana HG. CX. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Synthesis of three decadeoxynucleotides corresponding to the nucleotide sequence 51 to 70. Journal of Molecular Biology. 72: 375-405. PMID 4571082  1
1972 Khorana HG, Agarwal KL, Büchi H, Caruthers MH, Gupta NK, Kleppe K, Kumar A, Otsuka E, RajBhandary UL, Van de Sande JH, Sgaramella V, Terao T, Weber H, Yamada T. Studies on polynucleotides. 103. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Journal of Molecular Biology. 72: 209-17. PMID 4571075 DOI: 10.1016/0022-2836(72)90146-5  1
1972 Van de Sande JH, Loewen PC, Khorana HG. Studies on polynucleotides. 118. A further study of ribonucleotide incorporation into deoxyribonucleic acid chains by deoxyribonucleic acid polymerase I of Escherichia coli. The Journal of Biological Chemistry. 247: 6140-8. PMID 4568603  1
1970 Agarwal KL, Büchi H, Caruthers MH, Gupta N, Khorana HG, Kleppe K, Kumar A, Ohtsuka E, Rajbhandary UL, Van de Sande JH, Sgaramella V, Weber H, Yamada T. Total synthesis of the gene for an alanine transfer ribonucleic acid from yeast. Nature. 227: 27-34. PMID 5422620 DOI: 10.1038/227027a0  1
1970 Sgaramella V, Van de Sande JH, Khorana HG. Studies on polynucleotides, C. A novel joining reaction catalyzed by the T4-polynucleotide ligase. Proceedings of the National Academy of Sciences of the United States of America. 67: 1468-75. PMID 5274471  1
1970 Kleppe K, Van de Sande JH, Khorana HG. Polynucleotide ligase-catalyzed joining of deoxyribo-oligonucleotides on ribopolynucleotide templates and of ribo-oligonucleotides on deoxyribopolynucleotide templates. Proceedings of the National Academy of Sciences of the United States of America. 67: 68-73. PMID 5272330  1
1968 RajBhandary UL, Stuart A, Hoskinson RM, Khorana HG. Studies on polynucleotides. 78. Yeast phenylalanine transfer ribonucleic acid: terminal sequences. The Journal of Biological Chemistry. 243: 565-74. PMID 5637708  1
1968 Khorana HG, Büchi H, Caruthers MH, Chang SH, Gupta NK, Kumar A, Ohtsuka E, Sgaramella V, Weber H. Progress in the total synthesis of the gene for ala-tRNA. Cold Spring Harbor Symposia On Quantitative Biology. 33: 35-44. PMID 5254575  1
1967 Rajbhandary UL, Chang SH, Stuart A, Faulkner RD, Hoskinson RM, Khorana HG. Studies on polynucleotides, lxviii the primary structure of yeast phenylalanine transfer RNA. Proceedings of the National Academy of Sciences of the United States of America. 57: 751-8. PMID 16591527  1
1967 Ghosh HP, Söll D, Khorana HG. Studies on polynucleotides. LXVII. Initiation of protein synthesis in vitro as studied by using ribopolynucleotides with repeating nucleotide sequences as messengers. Journal of Molecular Biology. 25: 275-98. PMID 5340533  0.44
1967 Morgan AR, Wells RD, Khorana HG. Studies on polynucleotides. LXXIV. Direct translation in vitro of single-stranded DNA-like polymers with repeating nucleotide sequences in the presence of neomycin B. Journal of Molecular Biology. 26: 477-97. PMID 5339796  1
1967 Kössel H, Morgan AR, Khorana HG. Studies on polynucleotides. 73. Synthesis in vitro of polypeptides containing repeating tetrapeptide sequences dependent upon DNA-like polymers containing repeating tetranucleotide sequences: direction of reading of messenger RNA. Journal of Molecular Biology. 26: 449-75. PMID 5339795  0.92
1967 Wells RD, Büchi H, Kössel H, Ohtsuka E, Khorana HG. Studies on polynucleotides. LXX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating tetranucleotide sequences. Journal of Molecular Biology. 27: 265-72. PMID 4862296  1
1967 Wells RD, Jacob TM, Narang SA, Khorana HG. Studies on polynucleotides. LXIX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating trinucleotide sequences. Journal of Molecular Biology. 27: 237-63. PMID 4860495  1
1966 Morgan AR, Wells RD, Khorana HG. Studies on polynucleotides, lix. Further codon assignments from amino Acid incorporations directed by ribopolynucleotides containing repeating trinucleotide sequences. Proceedings of the National Academy of Sciences of the United States of America. 56: 1899-906. PMID 16591436  1
1966 Lohrmann R, Söll D, Hayatsu H, Ohtsuka E, Khorana HG. Studies on polynucleotides. LI. Syntheses of the 64 possible ribotrinucleotides derived from the four major ribomononucleotides. Journal of the American Chemical Society. 88: 819-29. PMID 5902563  0.52
1966 Söll D, Jones DS, Ohtsuka E, Faulkner RD, Lohrmann R, Hayatsu H, Khorana HG. Specificity of sRNA for recognition of codons as studied by the ribosomal binding technique. Journal of Molecular Biology. 19: 556-73. PMID 5338858  1
1966 Khorana HG, Büchi H, Ghosh H, Gupta N, Jacob TM, Kössel H, Morgan R, Narang SA, Ohtsuka E, Wells RD. Polynucleotide synthesis and the genetic code. Cold Spring Harbor Symposia On Quantitative Biology. 31: 39-49. PMID 5237635  1
1966 RajBhandary UL, Stuart A, Faulkner RD, Chang SH, Khorana HG. Nucleotide sequence studies on yeast phenylalanine sRNA. Cold Spring Harbor Symposia On Quantitative Biology. 31: 425-34. PMID 5237199  1
1966 Söll D, Cherayil J, Jones DS, Faulkner RD, Hapel A, Bock RM, Khorana HG. sRNA specificity for codon recognition as studied by the ribosomal binding technique. Cold Spring Harbor Symposia On Quantitative Biology. 31: 51-61. PMID 4866399  1
1966 Gupta NK, RajBhandary UL, Khorana HG. Missense suppression in tryptophan synthetase. Cold Spring Harbor Symposia On Quantitative Biology. 31: 499-500. PMID 4866397  1
1965 Wells RD, Ohtsuka E, Khorana HG. Studies on polynucleotides. L. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: a new double-stranded DNA-like polymer containing repeating dinucleotide sequences. Journal of Molecular Biology. 14: 221-37. PMID 5327651  1
1965 Söll D, Ohtsuka E, Jones DS, Lohrmann R, Hayatsu H, Nishimura S, Khorana HG. Studies on polynucleotides, XLIX. Stimulation of the binding of aminoacyl-sRNA's to ribosomes by ribotrinucleotides and a survey of codon assignments for 20 amino acids. Proceedings of the National Academy of Sciences of the United States of America. 54: 1378-85. PMID 5325653  0.52
1965 Jackson JF, Kornberg RD, Berg P, Rajbhandary UL, Stuart A, Khorana HG, Kornberg A. On the heterogeneity of the deoxyribonucleic acid associated with crystalline yeast cytochrome b2. Biochimica Et Biophysica Acta. 108: 243-8. PMID 4286177  1
1964 RAJBHANDARY UL, YOUNG RJ, KHORANA HG. STUDIES ON POLYNUCLEOTIDES. XXXII. THE LABELING OF END GROUPS IN POLYNUCLEOTIDE CHAINS: THE SELECTIVE PHOSPHORYLATION OF PHOSPHOMONOESTER GROUPS IN AMINO ACID ACCEPTOR RIBONUCLEIC ACIDS. The Journal of Biological Chemistry. 239: 3875-84. PMID 14257622  1
1959 TENER GM, GILHAM PT, RAZZELL WE, TURNER AF, KHORANA HG. Studies on the chemical synthesis and enzymatic degradation of desoxyribo-oligonucleotides. Annals of the New York Academy of Sciences. 81: 757-75. PMID 13837406  1
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