| Year |
Citation |
Score |
| 2023 |
Eeswara A, Pacheco-Spiewak A, Jergova S, Sagen J. Combined non-psychoactive Cannabis components cannabidiol and β-caryophyllene reduce chronic pain via CB1 interaction in a rat spinal cord injury model. Plos One. 18: e0282920. PMID 36913400 DOI: 10.1371/journal.pone.0282920 |
0.407 |
|
| 2023 |
Jergova S, Dugan EA, Sagen J. Attenuation of SCI-Induced Hypersensitivity by Intensive Locomotor Training and Recombinant GABAergic Cells. Bioengineering (Basel, Switzerland). 10. PMID 36671656 DOI: 10.3390/bioengineering10010084 |
0.457 |
|
| 2022 |
Jergova S, Hernandez M, Sagen J. Analgesic effect of recombinant GABAergic precursors releasing MVIIA in a model of peripheral nerve injury in rats. Molecular Pain. 17448069221129829. PMID 36113096 DOI: 10.1177/17448069221129829 |
0.501 |
|
| 2021 |
Jergova S, Martinez H, Hernandez M, Schachner B, Gross S, Sagen J. Development of a Phantom Limb Pain Model in Rats: Behavioral and Histochemical Evaluation. Frontiers in Pain Research (Lausanne, Switzerland). 2: 675232. PMID 35295448 DOI: 10.3389/fpain.2021.675232 |
0.323 |
|
| 2021 |
Jergova S, Perez C, Imperial JS, Gajavelli S, Jain A, Abin A, Olivera BM, Sagen J. Cannabinoid receptor agonists from Conus venoms alleviate pain-related behavior in rats. Pharmacology, Biochemistry, and Behavior. 173182. PMID 33774007 DOI: 10.1016/j.pbb.2021.173182 |
0.684 |
|
| 2020 |
Dugan EA, Schachner B, Jergova S, Sagen J. Intensive locomotor training provides sustained alleviation of chronic spinal cord injury associated neuropathic pain: A 2-year preclinical study. Journal of Neurotrauma. PMID 33218293 DOI: 10.1089/neu.2020.7378 |
0.422 |
|
| 2020 |
Dugan EA, Jergova S, Sagen J. Mutually beneficial effects of intensive exercise and GABAergic neural progenitor cell transplants in reducing neuropathic pain and spinal pathology in rats with spinal cord injury. Experimental Neurology. 113208. PMID 31962127 DOI: 10.1016/J.Expneurol.2020.113208 |
0.497 |
|
| 2019 |
Jergova S, Dugan E, Hernandez M, Arthur A, Restrepo M, Sagen J. (279) Management of SCI-Induced Chronic Pain in Rats: Intensive Locomotor Training and Recombinant GABAergic Cell Tranplants The Journal of Pain. 20: S44. DOI: 10.1016/J.Jpain.2019.01.201 |
0.526 |
|
| 2018 |
Dugan EA, Sagen J. A Novel Affective-Motivational Based Overground System for Detecting Spinal Cord Injury- associated Thermal and Mechanical Hypersensitivity in Rats. European Journal of Pain (London, England). PMID 29756383 DOI: 10.1002/Ejp.1245 |
0.494 |
|
| 2017 |
Jergova S, Gordon CE, Gajavelli S, Sagen J. Experimental Gene Therapy with Serine-Histogranin and Endomorphin 1 for the Treatment of Chronic Neuropathic Pain. Frontiers in Molecular Neuroscience. 10: 406. PMID 29276474 DOI: 10.3389/Fnmol.2017.00406 |
0.742 |
|
| 2016 |
Sagen J, Castellanos DA, Hama AT. Antinociceptive effects of topical mepivacaine in a rat model of HIV-associated peripheral neuropathic pain. Journal of Pain Research. 9: 361-71. PMID 27350758 DOI: 10.2147/Jpr.S104397 |
0.344 |
|
| 2016 |
Jergova S, Gajavelli S, Varghese MS, Shekane P, Sagen J. Analgesic effect of recombinant GABAergic cells in a model of peripheral neuropathic pain. Cell Transplantation. PMID 26817412 DOI: 10.3727/096368916X690782 |
0.778 |
|
| 2016 |
Jergova S, Gajavelli S, Pathak N, Sagen J. Recombinant neural progenitor transplants in the spinal dorsal horn alleviate chronic central neuropathic pain. Pain. PMID 26761378 DOI: 10.1097/J.Pain.0000000000000471 |
0.785 |
|
| 2015 |
Nasirinezhad F, Gajavelli S, Priddy B, Jergova S, Zadina J, Sagen J. Viral vectors encoding endomorphins and serine histogranin attenuate neuropathic pain symptoms after spinal cord injury in rats. Molecular Pain. 11: 2. PMID 25563474 DOI: 10.1186/1744-8069-11-2 |
0.76 |
|
| 2015 |
Dugan EA, Sagen J. An Intensive Locomotor Training Paradigm Improves Neuropathic Pain following Spinal Cord Compression Injury in Rats. Journal of Neurotrauma. 32: 622-32. PMID 25539034 DOI: 10.1089/Neu.2014.3692 |
0.468 |
|
| 2015 |
Nasirinezhad F, Jergova S, Pearson JP, Sagen J. Attenuation of persistent pain-related behavior by fatty acid amide hydrolase (FAAH) inhibitors in a rat model of HIV sensory neuropathy. Neuropharmacology. 95: 100-9. PMID 25486617 DOI: 10.1016/J.Neuropharm.2014.11.024 |
0.374 |
|
| 2015 |
Jergova S, Gordon CE, Gajavelli S, Sagen J. 654. Recombinant Gene and Cell Therapy With Serine-Histogranin and Endomorphin-1 for the Experimental Treatment of Chronic Neuropathic Pain Molecular Therapy. 23: S260. DOI: 10.1016/S1525-0016(16)34263-0 |
0.775 |
|
| 2014 |
Hama AT, Pearson JP, Sagen J. Effects of repeated dosing with mechanistically distinct antinociceptive ligands in a rat model of neuropathic spinal cord injury pain. Pharmacology Research & Perspectives. 2: e00034. PMID 25505583 DOI: 10.1002/prp2.34 |
0.394 |
|
| 2014 |
Hama A, Sagen J. Selective antinociceptive effects of a combination of the N-methyl-D-aspartate receptor peptide antagonist [Ser(1)]histogranin and morphine in rat models of pain. Pharmacology Research & Perspectives. 2: e00032. PMID 25505581 DOI: 10.1002/Prp2.32 |
0.468 |
|
| 2014 |
Hama AT, Germano P, Varghese MS, Cravatt BF, Milne GT, Pearson JP, Sagen J. Fatty acid amide hydrolase (FAAH) inhibitors exert pharmacological effects, but lack antinociceptive efficacy in rats with neuropathic spinal cord injury pain. Plos One. 9: e96396. PMID 24788435 DOI: 10.1371/Journal.Pone.0096396 |
0.526 |
|
| 2013 |
Hama A, Sagen J. Use of naturally occurring peptides for neuropathic spinal cord injury pain. Current Protein & Peptide Science. 14: 218-30. PMID 23721309 DOI: 10.2174/13892037113149990035 |
0.494 |
|
| 2013 |
Jergova S, Pathak N, Jani S, Gajavelli S, Sagen J. Targeting glutamate and opioid signaling by gene therapy in spinal cord injury-induced pain in rats The Journal of Pain. 14: S69. DOI: 10.1016/J.Jpain.2013.01.613 |
0.743 |
|
| 2012 |
Lee JW, Jergova S, Furmanski O, Gajavelli S, Sagen J. Predifferentiated GABAergic neural precursor transplants for alleviation of dysesthetic central pain following excitotoxic spinal cord injury. Frontiers in Physiology. 3: 167. PMID 22754531 DOI: 10.3389/Fphys.2012.00167 |
0.806 |
|
| 2012 |
Hama A, Sagen J. Combination Drug Therapy for Pain following Chronic Spinal Cord Injury. Pain Research and Treatment. 2012: 840486. PMID 22550581 DOI: 10.1155/2012/840486 |
0.367 |
|
| 2012 |
Hama A, Sagen J. Combinations of intrathecal gamma-amino-butyrate receptor agonists and N-methyl-d-aspartate receptor antagonists in rats with neuropathic spinal cord injury pain. European Journal of Pharmacology. 683: 101-8. PMID 22449374 DOI: 10.1016/J.Ejphar.2012.03.015 |
0.476 |
|
| 2012 |
Jergova S, Hentall ID, Gajavelli S, Varghese MS, Sagen J. Intraspinal transplantation of GABAergic neural progenitors attenuates neuropathic pain in rats: a pharmacologic and neurophysiological evaluation. Experimental Neurology. 234: 39-49. PMID 22193109 DOI: 10.1016/J.Expneurol.2011.12.005 |
0.764 |
|
| 2012 |
Hama AT, Broadhead A, Lorrain DS, Sagen J. The antinociceptive effect of the asthma drug ibudilast in rat models of peripheral and central neuropathic pain. Journal of Neurotrauma. 29: 600-10. PMID 21806469 DOI: 10.1089/Neu.2011.1863 |
0.515 |
|
| 2011 |
Hama A, Sagen J. Centrally mediated antinociceptive effects of cannabinoid receptor ligands in rat models of nociception. Pharmacology, Biochemistry, and Behavior. 100: 340-6. PMID 21958947 DOI: 10.1016/J.Pbb.2011.09.004 |
0.424 |
|
| 2011 |
Hama A, Sagen J. Activation of spinal and supraspinal cannabinoid-1 receptors leads to antinociception in a rat model of neuropathic spinal cord injury pain. Brain Research. 1412: 44-54. PMID 21813113 DOI: 10.1016/J.Brainres.2011.07.031 |
0.52 |
|
| 2011 |
Zhang YP, Fu ES, Sagen J, Levitt RC, Candiotti KA, Bethea JR, Brambilla R. Glial NF-κB inhibition alters neuropeptide expression after sciatic nerve injury in mice. Brain Research. 1385: 38-46. PMID 21352816 DOI: 10.1016/J.Brainres.2011.02.055 |
0.314 |
|
| 2011 |
Hama A, Sagen J. Antinociceptive effect of riluzole in rats with neuropathic spinal cord injury pain. Journal of Neurotrauma. 28: 127-34. PMID 20954888 DOI: 10.1089/Neu.2010.1539 |
0.548 |
|
| 2011 |
Jergova S, Varghese M, Collante D, Bartley S, Gajavelli S, Sagen J. Antinociceptive effect of recombinant neuroprogenitor intraspinal transplants in models of peripheral and central neuropathic pain The Journal of Pain. 12: P39. DOI: 10.1016/J.Jpain.2011.02.159 |
0.737 |
|
| 2010 |
Hama AT, Plum AW, Sagen J. Antinociceptive effect of ambroxol in rats with neuropathic spinal cord injury pain. Pharmacology, Biochemistry, and Behavior. 97: 249-55. PMID 20732348 DOI: 10.1016/J.Pbb.2010.08.006 |
0.543 |
|
| 2010 |
Fu ES, Zhang YP, Sagen J, Candiotti KA, Morton PD, Liebl DJ, Bethea JR, Brambilla R. Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammation after peripheral nerve injury. Pain. 148: 509-18. PMID 20097004 DOI: 10.1016/J.Pain.2010.01.001 |
0.363 |
|
| 2010 |
Hama AT, Sagen J. Cannabinoid receptor-mediated antinociception with acetaminophen drug combinations in rats with neuropathic spinal cord injury pain. Neuropharmacology. 58: 758-66. PMID 20035773 DOI: 10.1016/J.Neuropharm.2009.12.010 |
0.52 |
|
| 2009 |
Hama A, Sagen J. Sustained antinociceptive effect of cannabinoid receptor agonist WIN 55,212-2 over time in rat model of neuropathic spinal cord injury pain. Journal of Rehabilitation Research and Development. 46: 135-43. PMID 19533526 DOI: 10.1682/Jrrd.2008.04.0049 |
0.529 |
|
| 2009 |
Furmanski O, Gajavelli S, Lee JW, Collado ME, Jergova S, Sagen J. Combined extrinsic and intrinsic manipulations exert complementary neuronal enrichment in embryonic rat neural precursor cultures: an in vitro and in vivo analysis. The Journal of Comparative Neurology. 515: 56-71. PMID 19399893 DOI: 10.1002/Cne.22027 |
0.778 |
|
| 2009 |
Hama A, Sagen J. Antinociceptive effects of the marine snail peptides conantokin-G and conotoxin MVIIA alone and in combination in rat models of pain. Neuropharmacology. 56: 556-63. PMID 19010337 DOI: 10.1016/J.Neuropharm.2008.10.008 |
0.508 |
|
| 2009 |
Babul N, Hama A, Basler A, Sagen J. Antinociceptive effects of the local anesthetic TQ-1019 in painful HIV neuropathy The Journal of Pain. 10: S56. DOI: 10.1016/J.Jpain.2009.01.294 |
0.346 |
|
| 2009 |
Hama A, Plum A, Gajavelli S, Sagen J. Antinociceptive effect of ambroxol, a sodium channel blocker, on neuropathic spinal cord injury pain in rats The Journal of Pain. 10: S29. DOI: 10.1016/J.Jpain.2009.01.126 |
0.744 |
|
| 2008 |
Lee JW, Furmanski O, Castellanos DA, Daniels LA, Hama AT, Sagen J. Prolonged nociceptive responses to hind paw formalin injection in rats with a spinal cord injury. Neuroscience Letters. 439: 212-5. PMID 18524486 DOI: 10.1016/J.Neulet.2008.05.030 |
0.785 |
|
| 2008 |
Gajavelli S, Castellanos DA, Furmanski O, Schiller PC, Sagen J. Sustained analgesic peptide secretion and cell labeling using a novel genetic modification. Cell Transplantation. 17: 445-55. PMID 18522246 DOI: 10.3727/096368908784423265 |
0.773 |
|
| 2008 |
Herzberg U, Hama A, Sagen J. Spinal subarachnoid adrenal medullary transplants reduce hind paw swelling and peripheral nerve transport following formalin injection in rats. Brain Research. 1198: 85-92. PMID 18258218 DOI: 10.1016/J.Brainres.2008.01.026 |
0.486 |
|
| 2007 |
Hama A, Sagen J. Behavioral characterization and effect of clinical drugs in a rat model of pain following spinal cord compression. Brain Research. 1185: 117-28. PMID 17935699 DOI: 10.1016/J.Brainres.2007.09.013 |
0.517 |
|
| 2007 |
Castellanos DA, Daniels LA, Morales MP, Hama AT, Sagen J. Expansion of formalin-evoked Fos-immunoreactivity in rats with a spinal cord injury. Neuroscience Research. 58: 386-93. PMID 17531342 DOI: 10.1016/J.Neures.2007.04.011 |
0.527 |
|
| 2007 |
Guenot M, Lee JW, Nasirinezhad F, Sagen J. Deafferentation pain resulting from cervical posterior rhizotomy is alleviated by chromaffin cell transplants into the rat spinal subarachnoid space. Neurosurgery. 60: 919-25; discussion 9. PMID 17460528 DOI: 10.1227/01.Neu.0000255435.29118.3D |
0.561 |
|
| 2007 |
Hentall ID, Hargraves WA, Sagen J. Inhibition by the chromaffin cell-derived peptide serine-histogranin in the rat's dorsal horn. Neuroscience Letters. 419: 88-92. PMID 17442490 DOI: 10.1016/J.Neulet.2007.03.056 |
0.385 |
|
| 2007 |
Fu ES, Zhang YP, Sagen J, Yang ZQ, Bethea JR. Transgenic glial nuclear factor-kappa B inhibition decreases formalin pain in mice. Neuroreport. 18: 713-7. PMID 17426605 DOI: 10.1097/Wnr.0B013E3280D9E869 |
0.359 |
|
| 2007 |
Voda J, Hama A, Sagen J. FK506 reduces the severity of cutaneous hypersensitivity in rats with a spinal cord contusion. Neuroscience Research. 58: 95-9. PMID 17346839 DOI: 10.1016/J.Neures.2007.02.004 |
0.503 |
|
| 2007 |
Hama A, Sagen J. Altered antinociceptive efficacy of tramadol over time in rats with painful peripheral neuropathy. European Journal of Pharmacology. 559: 32-7. PMID 17207479 DOI: 10.1016/J.Ejphar.2006.11.047 |
0.445 |
|
| 2007 |
Hama A, Sagen J. Antinociceptive effect of cannabinoid agonist WIN 55,212-2 in rats with a spinal cord injury. Experimental Neurology. 204: 454-7. PMID 17045264 DOI: 10.1016/J.Expneurol.2006.09.002 |
0.534 |
|
| 2006 |
Hama A, Basler A, Sagen J. Enhancement of morphine antinociception with the peptide N-methyl-D-aspartate receptor antagonist [Ser1]-histogranin in the rat formalin test. Brain Research. 1095: 59-64. PMID 16712813 DOI: 10.1016/J.Brainres.2006.04.012 |
0.387 |
|
| 2006 |
Fu ES, Zhang YP, Sagen J, Bethea JR. Role of Glial NF-??B Inhibition on Pain Behavior After Sciatic Constriction Nerve Injury in Mice Journal of Neurosurgical Anesthesiology. 18: 313-314. DOI: 10.1097/00008506-200610000-00095 |
0.353 |
|
| 2006 |
Voda J, Castro A, Maldonado A, Sagen J. Chromaffin cell-seeded Schwann cell bridges improve locomotor recovery in the spinally transected rat by regeneration and monoaminergic stimulation Experimental Neurology. 198: 592-593. DOI: 10.1016/J.Expneurol.2006.02.101 |
0.43 |
|
| 2006 |
Maldonado A, Voda J, Castro A, Sagen J. Improved functional recovery in the rat contusion model of spinal cord injury using co-grafts of bovine chromaffin and Schwann cells Experimental Neurology. 198: 580. DOI: 10.1016/J.Expneurol.2006.02.070 |
0.471 |
|
| 2005 |
NasiriNezhad F, Sagen J. NMDA antagonist peptide supplementation enhances pain alleviation by adrenal medullary transplants. Cell Transplantation. 14: 203-11. PMID 15929555 DOI: 10.3727/000000005783983115 |
0.537 |
|
| 2004 |
Caban AJ, Hama AT, Lee JW, Sagen J. Enhanced antinociception by nicotinic receptor agonist epibatidine and adrenal medullary transplants in the spinal subarachnoid space. Neuropharmacology. 47: 106-16. PMID 15165838 DOI: 10.1016/J.Neuropharm.2004.03.008 |
0.459 |
|
| 2004 |
Schumm MA, Castellanos DA, Frydel BR, Sagen J. Improved neural progenitor cell survival when cografted with chromaffin cells in the rat striatum. Experimental Neurology. 185: 133-42. PMID 14697324 DOI: 10.1016/J.Expneurol.2003.09.017 |
0.423 |
|
| 2003 |
Sagen J. Cellular therapies for spinal cord injury: what will the FDA need to approve moving from the laboratory to the human? Journal of Rehabilitation Research and Development. 40: 71-9. PMID 15077651 DOI: 10.1682/Jrrd.2003.08.0071 |
0.428 |
|
| 2003 |
Hama A, Woon Lee J, Sagen J. Differential efficacy of intrathecal NMDA receptor antagonists on inflammatory mechanical and thermal hyperalgesia in rats. European Journal of Pharmacology. 459: 49-58. PMID 12505533 DOI: 10.1016/S0014-2999(02)02828-5 |
0.41 |
|
| 2002 |
Sagen J, Whittemore SR. Emerging Strategies in Neural Transplantation and Repair: A Special Issue Based on the Eighth Annual Conference. Cell Transplantation. 11: 181-183. PMID 28858599 DOI: 10.3727/096020198389906 |
0.317 |
|
| 2002 |
Schumm MA, Castellanos DA, Frydel BR, Sagen J. Enhanced viability and neuronal differentiation of neural progenitors by chromaffin cell co-culture. Brain Research. Developmental Brain Research. 137: 115-25. PMID 12220703 DOI: 10.1016/S0165-3806(02)00415-7 |
0.351 |
|
| 2002 |
Siegan JB, Herzberg U, Frydel BR, Sagen J. Adrenal medullary transplants reduce formalin-evoked c-fos expression in the rat spinal cord. Brain Research. 944: 174-83. PMID 12106677 DOI: 10.1016/S0006-8993(02)02742-7 |
0.521 |
|
| 2002 |
Castellanos DA, Tsoulfas P, Frydel BR, Gajavelli S, Bes JC, Sagen J. TrkC overexpression enhances survival and migration of neural stem cell transplants in the rat spinal cord. Cell Transplantation. 11: 297-307. PMID 12075995 DOI: 10.3727/096020198389942 |
0.747 |
|
| 2002 |
Hama A, Sagen J. Selective antihyperalgesic effect of [Ser1] histogranin on complete Freund's adjuvant-induced hyperalgesia in rats. Pain. 95: 15-21. PMID 11790463 DOI: 10.1016/S0304-3959(01)00368-2 |
0.472 |
|
| 2001 |
Vizzardelli C, Potter ED, Berney T, Pileggi A, Inverardi L, Ricordi C, Sagen J. Automated method for isolation of adrenal medullary chromaffin cells from neonatal porcine glands. Cell Transplantation. 10: 689-96. PMID 11814111 DOI: 10.3727/000000001783986288 |
0.318 |
|
| 2001 |
Herzberg U, Sagen J. Peripheral nerve exposure to HIV viral envelope protein gp120 induces neuropathic pain and spinal gliosis. Journal of Neuroimmunology. 116: 29-39. PMID 11311327 DOI: 10.1016/S0165-5728(01)00288-0 |
0.425 |
|
| 2001 |
Hentall ID, Noga BR, Sagen J. Spinal allografts of adrenal medulla block nociceptive facilitation in the dorsal horn. Journal of Neurophysiology. 85: 1788-92. PMID 11287501 DOI: 10.1152/Jn.2001.85.4.1788 |
0.51 |
|
| 2000 |
Eaton MJ, Martinez M, Karmally S, Lopez T, Sagen J. Initial characterization of the transplant of immortalized chromaffin cells for the attenuation of chronic neuropathic pain. Cell Transplantation. 9: 637-56. PMID 11144961 DOI: 10.1177/096368970000900509 |
0.556 |
|
| 2000 |
Hentall ID, Sagen J. The alleviation of pain by cell transplantation. Progress in Brain Research. 127: 535-50. PMID 11142047 DOI: 10.1016/S0079-6123(00)27027-1 |
0.531 |
|
| 2000 |
Yadid G, Zangen A, Herzberg U, Nakash R, Sagen J. Alterations in endogenous brain beta-endorphin release by adrenal medullary transplants in the spinal cord. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 709-16. PMID 11063926 DOI: 10.1016/S0893-133X(00)00152-4 |
0.52 |
|
| 2000 |
Eaton MJ, Frydel BR, Lopez TL, Nie XT, Huang J, McKillop J, Sagen J. Generation and initial characterization of conditionally immortalized chromaffin cells. Journal of Cellular Biochemistry. 79: 38-57. PMID 10906754 DOI: 10.1002/1097-4644(2000)79:1<38::Aid-Jcb50>3.0.Co;2-U |
0.385 |
|
| 2000 |
Lazorthes Y, Sagen J, Sallerin B, Tkaczuk J, Duplan H, Sol JC, Tafani M, Bès JC. Human chromaffin cell graft into the CSF for cancer pain management: a prospective phase II clinical study. Pain. 87: 19-32. PMID 10863042 DOI: 10.1016/S0304-3959(00)00263-3 |
0.422 |
|
| 2000 |
Duplan H, Bès JC, Tafani M, Sallerin B, Sagen J, Ohayon E, Lazorthes Y, Tkaczuk J. Adrenal medullary explants as an efficient tool for pain control: adhesive biomolecular components are involved in graft function ex vivo. Experimental Neurology. 163: 331-47. PMID 10833307 DOI: 10.1006/Exnr.1999.7352 |
0.44 |
|
| 2000 |
Hentall ID, Sagen J. Spinal CSF from rats with painful peripheral neuropathy evokes catecholamine release from chromaffin cells in vitro. Neuroscience Letters. 286: 95-8. PMID 10825645 DOI: 10.1016/S0304-3940(00)01112-5 |
0.534 |
|
| 1999 |
Hama AT, Siegan JB, Herzberg U, Sagen J. NMDA-induced spinal hypersensitivity is reduced by naturally derived peptide analog [Ser1]histogranin. Pharmacology, Biochemistry, and Behavior. 62: 67-74. PMID 9972847 DOI: 10.1016/S0091-3057(98)00132-4 |
0.481 |
|
| 1998 |
Siegan JB, Sagen J. Adrenal medullary transplants attenuate sensorimotor dysfunction in rats with peripheral neuropathy. Pharmacology, Biochemistry, and Behavior. 59: 97-104. PMID 9443542 DOI: 10.1016/S0091-3057(97)00326-2 |
0.477 |
|
| 1998 |
Sagen J. Cellular transplantation for intractable pain. Advances in Pharmacology (San Diego, Calif.). 42: 579-82. PMID 9327968 |
0.353 |
|
| 1997 |
Czech KA, Ryan JW, Sagen J, Pappas GD. The influence of xenotransplant immunogenicity and immunosuppression on host MHC expression in the rat CNS. Experimental Neurology. 147: 66-83. PMID 9294404 DOI: 10.1006/Exnr.1997.6589 |
0.369 |
|
| 1997 |
Siegan JB, Hama AT, Sagen J. Suppression of neuropathic pain by a naturally-derived peptide with NMDA antagonist activity. Brain Research. 755: 331-4. PMID 9175901 DOI: 10.1016/S0006-8993(97)00183-2 |
0.468 |
|
| 1997 |
Siegan JB, Sagen J. A natural peptide with NMDA inhibitory activity reduces tonic pain in the formalin model. Neuroreport. 8: 1379-81. PMID 9172139 DOI: 10.1097/00001756-199704140-00012 |
0.442 |
|
| 1997 |
Siegan JB, Sagen J. Attenuation of formalin pain responses in the rat by adrenal medullary transplants in the spinal subarachnoid space. Pain. 70: 279-85. PMID 9150303 DOI: 10.1016/S0304-3959(97)03335-6 |
0.469 |
|
| 1997 |
Bresjanac M, Sagen J, Seigel G, Paino CL, Kordower J, Gash DM. Xenogeneic adrenal medulla graft rejection rather than survival leads to increased rat striatal tyrosine hydroxylase immunoreactivity. Journal of Neuropathology and Experimental Neurology. 56: 490-8. PMID 9143262 DOI: 10.1097/00005072-199705000-00005 |
0.401 |
|
| 1997 |
Ibuki T, Hama AT, Wang XT, Pappas GD, Sagen J. Loss of GABA-immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion of recovery by adrenal medullary grafts. Neuroscience. 76: 845-58. PMID 9135056 DOI: 10.1016/S0306-4522(96)00341-7 |
0.37 |
|
| 1996 |
Siegan JB, Hama AT, Sagen J. Alterations in rat spinal cord cGMP by peripheral nerve injury and adrenal medullary transplantation. Neuroscience Letters. 215: 49-52. PMID 8880751 DOI: 10.1016/S0304-3940(96)12962-1 |
0.575 |
|
| 1996 |
Wang XT, Pappas GD, Sagen J, Unnerstall JR. Cells expressing preproenkephalin mRNA in the rat pineal gland are not serotonin-producing pinealocytes: evidence using in situ hybridization combined with immunocytochemistry for serotonin. Cellular and Molecular Neurobiology. 16: 73-84. PMID 8714561 DOI: 10.1007/Bf02578388 |
0.333 |
|
| 1996 |
Czech KA, Pollak R, Pappas GD, Sagen J. Bovine chromaffin cells for CNS transplantation do not elicit xenogeneic T cell proliferative responses in vitro. Cell Transplantation. 5: 257-67. PMID 8689036 DOI: 10.1016/0963-6897(95)02033-0 |
0.377 |
|
| 1996 |
Hama AT, Pappas GD, Sagen J. Adrenal medullary implants reduce transsynaptic degeneration in the spinal cord of rats following chronic constriction nerve injury. Experimental Neurology. 137: 81-93. PMID 8566215 DOI: 10.1006/Exnr.1996.0009 |
0.467 |
|
| 1995 |
Lazorthes Y, Bès JC, Sagen J, Tafani M, Tkaczuk J, Sallerin B, Nahri I, Verdié JC, Ohayon E, Caratero C. Transplantation of human chromaffin cells for control of intractable cancer pain. Acta Neurochirurgica. Supplement. 64: 97-100. PMID 8748593 |
0.431 |
|
| 1995 |
Wang H, Sagen J. Attenuation of pain-related hyperventilation in adjuvant arthritic rats with adrenal medullary transplants in the spinal subarachnoid space. Pain. 63: 313-20. PMID 8719531 DOI: 10.1016/0304-3959(95)00058-5 |
0.551 |
|
| 1995 |
Czech KA, Sagen J. Update on cellular transplantation into the CNS as a novel therapy for chronic pain. Progress in Neurobiology. 46: 507-29. PMID 8532850 DOI: 10.1016/0301-0082(95)00011-J |
0.524 |
|
| 1995 |
Schueler SB, Sagen J, Pappas GD, Kordower JH. Long-term viability of isolated bovine adrenal medullary chromaffin cells following intrastriatal transplantation. Cell Transplantation. 4: 55-64. PMID 7728334 DOI: 10.1016/0963-6897(94)00939-H |
0.391 |
|
| 1995 |
Siegan JB, Sagen J. Attenuation of NMDA-induced spinal hypersensitivity by adrenal medullary transplants. Brain Research. 680: 88-98. PMID 7663988 DOI: 10.1016/0006-8993(95)00248-O |
0.529 |
|
| 1995 |
Sortwell CE, Pappas GD, Sagen J. Chromaffin cell xenografts in the rat neocortex can produce antidepressive activity in the forced swimming test. Experimental Brain Research. 103: 59-69. PMID 7615038 DOI: 10.1007/Bf00241965 |
0.651 |
|
| 1995 |
Dougherty DD, Sortwell CE, Sagen J. Pharmacologic specificity of antidepressive activity by monoaminergic neural transplants. Psychopharmacology. 118: 10-8. PMID 7597115 DOI: 10.1007/BF02245244 |
0.623 |
|
| 1995 |
Hama AT, Unnerstall JR, Siegan JB, Sagen J. Modulation of NMDA receptor expression in the rat spinal cord by peripheral nerve injury and adrenal medullary grafting. Brain Research. 687: 103-13. PMID 7583294 DOI: 10.1016/0006-8993(95)00476-7 |
0.444 |
|
| 1995 |
Sagen J, Wang H. Adrenal medullary grafts suppress c-fos induction in spinal neurons of arthritic rats. Neuroscience Letters. 192: 181-4. PMID 7566645 DOI: 10.1016/0304-3940(95)11640-I |
0.562 |
|
| 1994 |
Sagen J, Ortega JD. Influence of the CNS environment on chromaffin cell survival and catecholamine secretion patterns. Journal of Neurochemistry. 63: 1159-62. PMID 8051558 DOI: 10.1046/J.1471-4159.1994.63031159.X |
0.388 |
|
| 1994 |
Hama AT, Sagen J. Induction of spinal NADPH-diaphorase by nerve injury is attenuated by adrenal medullary transplants. Brain Research. 640: 345-51. PMID 8004464 DOI: 10.1016/0006-8993(94)91892-9 |
0.505 |
|
| 1994 |
Hama AT, Sagen J, Pappas GD. Morphological characterization of dorsal horn spinal neurons in rats with unilateral constriction nerve injury: a preliminary study. Neurological Research. 16: 297-304. PMID 7984262 DOI: 10.1080/01616412.1994.11740243 |
0.471 |
|
| 1994 |
Wang H, Sagen J. Absence of appreciable tolerance and morphine cross-tolerance in rats with adrenal medullary transplants in the spinal cord. Neuropharmacology. 33: 681-92. PMID 7936104 DOI: 10.1016/0028-3908(94)90174-0 |
0.471 |
|
| 1994 |
Hama AT, Sagen J. Alleviation of neuropathic pain symptoms by xenogeneic chromaffin cell grafts in the spinal subarachnoid space. Brain Research. 651: 183-93. PMID 7922566 DOI: 10.1016/0006-8993(94)90696-3 |
0.548 |
|
| 1994 |
Sortwell CE, Petty F, Kramer G, Sagen J. In vivo release of catecholamines from xenogeneic chromaffin cell grafts with antidepressive activity. Experimental Neurology. 130: 1-8. PMID 7821384 DOI: 10.1006/Exnr.1994.1178 |
0.659 |
|
| 1994 |
Wang H, Sagen J. Optimization of adrenal medullary allograft conditions for pain alleviation. Journal of Neural Transplantation & Plasticity. 5: 49-64. PMID 7819372 DOI: 10.1155/Np.1994.49 |
0.467 |
|
| 1994 |
Ortega JD, Sagen J, Pappas GD. Origin of afferent projections into bovine chromaffin cell implants in the rat periaqueductal gray determined by retrograde and anterograde tracing. Journal of Neural Transplantation & Plasticity. 5: 31-48. PMID 7819371 DOI: 10.1155/Np.1994.31 |
0.391 |
|
| 1994 |
Joseph JM, Goddard MB, Mills J, Padrun V, Zurn A, Zielinski B, Favre J, Gardaz JP, Mosimann F, Sagen J. Transplantation of encapsulated bovine chromaffin cells in the sheep subarachnoid space: a preclinical study for the treatment of cancer pain. Cell Transplantation. 3: 355-64. PMID 7530113 DOI: 10.1177/096368979400300502 |
0.454 |
|
| 1994 |
Sagen J, Ortega JD, Pappas GD. Neuropeptide and Catecholamine Delivery to Central Nervous System by Implanted Chromaffin Cells Methods in Neurosciences. 21: 348-368. DOI: 10.1016/B978-0-12-185291-7.50027-8 |
0.411 |
|
| 1993 |
Sagen J, Pappas GD, Winnie AP. ALLEVIATION OF PAIN IN CANCER PATIENTS BY ADRENAL MEDULLARY TRANSPLANTS IN THE SPINAL SUBARACHNOID SPACE. Cell Transplantation. 2: 259-266. PMID 28148371 DOI: 10.1177/096368979300200310 |
0.529 |
|
| 1993 |
Hama AT, Sagen J. Reduced pain-related behavior by adrenal medullary transplants in rats with experimental painful peripheral neuropathy. Pain. 52: 223-31. PMID 8384360 DOI: 10.1016/0304-3959(93)90135-C |
0.529 |
|
| 1993 |
Sortwell CE, Sagen J. Induction of antidepressive activity by monoaminergic transplants in rat neocortex. Pharmacology, Biochemistry, and Behavior. 46: 225-30. PMID 8255915 DOI: 10.1016/0091-3057(93)90345-T |
0.653 |
|
| 1993 |
Ortega JD, Sagen J. Pharmacologic characterization of opioid peptide release from chromaffin cell transplants using a brain slice superfusion method. Experimental Brain Research. 95: 381-7. PMID 8224064 DOI: 10.1007/Bf00227130 |
0.449 |
|
| 1993 |
Winnie AP, Pappas GD, Das Gupta TK, Wang H, Ortega JD, Sagen J. Subarachnoid adrenal medullary transplants for terminal cancer pain. A report of preliminary studies. Anesthesiology. 79: 644-53. PMID 8214743 DOI: 10.1097/00000542-199310000-00004 |
0.517 |
|
| 1993 |
Schueler SB, Ortega JD, Sagen J, Kordower JH. Robust survival of isolated bovine adrenal chromaffin cells following intrastriatal transplantation: a novel hypothesis of adrenal graft viability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 4496-510. PMID 8105042 DOI: 10.1523/Jneurosci.13-10-04496.1993 |
0.367 |
|
| 1993 |
Sagen J, Wang H, Tresco PA, Aebischer P. Transplants of immunologically isolated xenogeneic chromaffin cells provide a long-term source of pain-reducing neuroactive substances. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2415-23. PMID 7684773 DOI: 10.1523/Jneurosci.13-06-02415.1993 |
0.535 |
|
| 1993 |
Garces YI, Rabito SF, Minshall RD, Sagen J. Lack of potent antinociceptive activity by substance P antagonist CP-96,345 in the rat spinal cord. Life Sciences. 52: 353-60. PMID 7678436 DOI: 10.1016/0024-3205(93)90148-V |
0.461 |
|
| 1992 |
Ortega JD, Sagen J, Pappas GD. Survival and integration of bovine chromaffin cells transplanted into rat central nervous system without exogenous trophic factors. The Journal of Comparative Neurology. 323: 13-24. PMID 1430313 DOI: 10.1002/Cne.903230103 |
0.454 |
|
| 1992 |
Sagen J. Chromaffin cell transplants for alleviation of chronic pain. Asaio Journal (American Society For Artificial Internal Organs : 1992). 38: 24-8. PMID 1372836 DOI: 10.1097/00002480-199201000-00007 |
0.521 |
|
| 1992 |
Ortega JD, Sagen J, Pappas GD. Short-term immunosuppression enhances long-term survival of bovine chromaffin cell xenografts in rat CNS. Cell Transplantation. 1: 33-41. PMID 1364246 DOI: 10.1177/096368979200100107 |
0.4 |
|
| 1992 |
Sagen J, Pappas GD, Winnie AP. Alleviation of Chronic Cancer Pain by Adrenal Medullary Transplants in the Spinal Subarachnoid Space Journal of Neural Transplantation and Plasticity. 3: 336-337. DOI: 10.1155/NP.1992.336 |
0.395 |
|
| 1992 |
Sagen J, Pappas GD, Winnie AP. Alleviation of chronic cancer pain by adrenal medullary transplants in the spinal subarachnoid space Journal of Neural Transplantation and Plasticity. 3: 336-337. DOI: 10.1155/Np.1992.336 |
0.493 |
|
| 1992 |
Sortwell CE, Sagen J. Behavioral and biochemical assessment of monoaminergic neural transplants to rat frontal neocortex Journal of Neural Transplantation and Plasticity. 3: 307-308. DOI: 10.1155/Np.1992.307 |
0.638 |
|
| 1992 |
Schueler SB, Ortega JD, Sagen J, Kordower JH. Non-Chromaffin Cell Constituents of the Adrenal Medulla are Detrimental to the Survival of Grafted Adrenal Chromaffin Cells: Studies in Rats and Non-Human Primates Journal of Neural Transplantation and Plasticity. 3: 209-210. DOI: 10.1155/Np.1992.209 |
0.364 |
|
| 1991 |
Sagen J, Kemmler JE, Wang H. Adrenal medullary transplants increase spinal cord cerebrospinal fluid catecholamine levels and reduce pain sensitivity. Journal of Neurochemistry. 56: 623-7. PMID 1988560 DOI: 10.1111/J.1471-4159.1991.Tb08195.X |
0.554 |
|
| 1991 |
Aebischer P, Tresco PA, Sagen J, Winn SR. Transplantation of microencapsulated bovine chromaffin cells reduces lesion-induced rotational asymmetry in rats. Brain Research. 560: 43-9. PMID 1760745 DOI: 10.1016/0006-8993(91)91212-J |
0.374 |
|
| 1991 |
Winnie AP, Krolick TJ, Sagen J, Pappas GD, Wang H. SUBARACHNOID ADRENAL MEDULLARY TRANSPLANTATION Anesthesiology. 75: A695. DOI: 10.1097/00000542-199109001-00694 |
0.363 |
|
| 1990 |
Sagen J, Wang H. Prolonged analgesia by enkephalinase inhibition in rats with spinal cord adrenal medullary transplants. European Journal of Pharmacology. 179: 427-33. PMID 2364994 DOI: 10.1016/0014-2999(90)90184-8 |
0.532 |
|
| 1990 |
Sagen J, Wang H, Pappas GD. Adrenal medullary implants in the rat spinal cord reduce nociception in a chronic pain model. Pain. 42: 69-79. PMID 2235000 DOI: 10.1016/0304-3959(90)91093-X |
0.544 |
|
| 1990 |
Sagen J, Pappas GD, Ortega JD. Host-graft relationships of isolated bovine chromaffin cells in rat periaqueductal grey. Journal of Neurocytology. 19: 697-707. PMID 2077111 DOI: 10.1007/Bf01188038 |
0.458 |
|
| 1990 |
Sagen J, Sortwell CE, Pappas GD. Monoaminergic neural transplants prevent learned helplessness in a rat depression model. Biological Psychiatry. 28: 1037-48. PMID 1963093 DOI: 10.1016/0006-3223(90)90604-Z |
0.642 |
|
| 1989 |
Sagen J, Kemmler JE. Increased levels of Met-enkephalin-like immunoreactivity in the spinal cord CSF of rats with adrenal medullary transplants. Brain Research. 502: 1-10. PMID 2819448 DOI: 10.1016/0006-8993(89)90455-1 |
0.525 |
|
| 1988 |
Pappas GD, Sagen J. The fine structure of chromaffin cell implants in the pain modulatory regions of the rat periaqueductal gray and spinal cord. Progress in Brain Research. 78: 513-20. PMID 3247445 DOI: 10.1016/S0079-6123(08)60325-8 |
0.535 |
|
| 1988 |
Pappas GD, Sagen J. Fine structural correlates of vascular permeability of chromaffin cell transplants in CNS pain modulatory regions. Experimental Neurology. 102: 280-9. PMID 3197788 |
0.351 |
|
| 1988 |
Sagen J, Pappas GD. Pharmacologic consequences of the vascular permeability of chromaffin cell transplants in CNS pain modulatory regions. Experimental Neurology. 102: 290-7. PMID 2904375 DOI: 10.1016/0014-4886(88)90222-1 |
0.42 |
|
| 1987 |
Sagen J, Pappas GD, Perlow MJ. Fine structure of adrenal medullary grafts in the pain modulatory regions of the rat periaqueductal gray. Experimental Brain Research. 67: 380-90. PMID 3622696 DOI: 10.1007/Bf00248558 |
0.412 |
|
| 1987 |
Sagen J, Pappas GD, Perlow MJ. Alterations in nociception following adrenal medullary transplants into the rat periaqueductal gray. Experimental Brain Research. 67: 373-9. PMID 3622695 DOI: 10.1007/Bf00248557 |
0.465 |
|
| 1987 |
Sagen J, Proudfit HK. Release of endogenous monoamines into spinal cord superfusates following the microinjection of phentolamine into the nucleus raphe magnus. Brain Research. 406: 246-54. PMID 3567625 DOI: 10.1016/0006-8993(87)90789-X |
0.701 |
|
| 1987 |
Sagen J, Pappas GD. Morphological and functional correlates of chromaffin cell transplants in CNS pain modulatory regions. Annals of the New York Academy of Sciences. 495: 306-33. PMID 3474947 DOI: 10.1111/J.1749-6632.1987.Tb23683.X |
0.463 |
|
| 1986 |
Sagen J, Pappas GD, Perlow MJ. Adrenal medullary tissue transplants in the rat spinal cord reduce pain sensitivity. Brain Research. 384: 189-94. PMID 3790994 DOI: 10.1016/0006-8993(86)91238-2 |
0.57 |
|
| 1986 |
Pappas GD, Sagen J. Fine structure of PC12 cell implants in the rat spinal cord. Neuroscience Letters. 70: 59-64. PMID 3774220 DOI: 10.1016/0304-3940(86)90437-4 |
0.441 |
|
| 1986 |
Sagen J, Proudfit HK. Alterations in nociception following lesions of the A5 catecholamine nucleus. Brain Research. 370: 93-101. PMID 3754780 DOI: 10.1016/0006-8993(86)91108-X |
0.63 |
|
| 1986 |
Sagen J, Pappas GD, Pollard HB. Analgesia induced by isolated bovine chromaffin cells implanted in rat spinal cord. Proceedings of the National Academy of Sciences of the United States of America. 83: 7522-6. PMID 3463981 DOI: 10.1073/Pnas.83.19.7522 |
0.517 |
|
| 1985 |
Sagen J, Proudfit HK. Evidence for pain modulation by pre- and postsynaptic noradrenergic receptors in the medulla oblongata. Brain Research. 331: 285-93. PMID 2859092 DOI: 10.1016/0006-8993(85)91554-9 |
0.655 |
|
| 1984 |
Sagen J, Proudfit HK. Effect of intrathecally administered noradrenergic antagonists on nociception in the rat. Brain Research. 310: 295-301. PMID 6548399 DOI: 10.1016/0006-8993(84)90152-5 |
0.705 |
|
| 1983 |
Sagen J, Winker MA, Proudfit HK. Hypoalgesia induced by the local injection of phentolamine in the nucleus raphe magnus: blockade by depletion of spinal cord monoamines. Pain. 16: 253-63. PMID 6310470 DOI: 10.1016/0304-3959(83)90113-6 |
0.706 |
|
| 1981 |
Sagen J, Proudfit HK. Hypoalgesia induced by blockade of noradrenergic projections to the raphe magnus: reversal by blockade of noradrenergic projections to the spinal cord. Brain Research. 223: 391-6. PMID 7284816 DOI: 10.1016/0006-8993(81)91153-7 |
0.663 |
|
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