César Milstein - Publications

Affiliations: 
Molecular Biology MRC Laboratory of Molecular Biology, Cambridge, England, United Kingdom 
Area:
Immunology
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1984/milstein.html

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Year Citation  Score
2008 Milstein C, Galfre G, Secher DS, Springer T. Monoclonal Antibodies and Cell Surface Antigens Human Genetics: Possibilities and Realities. 251-281. DOI: 10.1002/9780470720486.ch11  0.445
2002 Rada C, Jarvis JM, Milstein C. AID-GFP chimeric protein increases hypermutation of Ig genes with no evidence of nuclear localization. Proceedings of the National Academy of Sciences of the United States of America. 99: 7003-8. PMID 12011459 DOI: 10.1073/Pnas.092160999  0.317
2001 Rada C, Milstein C. The intrinsic hypermutability of antibody heavy and light chain genes decays exponentially. The Embo Journal. 20: 4570-6. PMID 11500383 DOI: 10.1093/Emboj/20.16.4570  0.344
2001 Sale JE, Bemark M, Williams GT, Jolly CJ, Ehrenstein MR, Rada C, Milstein C, Neuberger MS. In vivo and in vitro studies of immunoglobulin gene somatic hypermutation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 21-8. PMID 11205326 DOI: 10.1098/Rstb.2000.0744  0.31
2000 Neuberger MS, Ehrenstein MR, Rada C, Sale J, Batista FD, Williams G, Milstein C. Memory in the B-cell compartment: antibody affinity maturation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 355: 357-60. PMID 10794054 DOI: 10.1098/Rstb.2000.0573  0.364
1999 Milstein C. The hybridoma revolution: an offshoot of basic research. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 21: 966-73. PMID 10517870 DOI: 10.1002/(Sici)1521-1878(199911)21:11<966::Aid-Bies9>3.0.Co;2-Z  0.364
1996 Goyenechea B, Milstein C. Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation. Proceedings of the National Academy of Sciences of the United States of America. 93: 13979-84. PMID 8943046 DOI: 10.1073/Pnas.93.24.13979  0.335
1996 Milstein C, Neuberger MS. Maturation of the immune response. Advances in Protein Chemistry. 49: 451-85. PMID 8908303 DOI: 10.1016/S0065-3233(08)60494-5  0.374
1996 Aoufouchi S, Yélamos J, Milstein C. Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis. Cell. 85: 415-22. PMID 8616896 DOI: 10.1016/S0092-8674(00)81119-8  0.305
1995 Chui YL, Lozano F, Jarvis JM, Pannell R, Milstein C. A reporter gene to analyse the hypermutation of immunoglobulin genes. Journal of Molecular Biology. 249: 555-63. PMID 7783211 DOI: 10.1006/Jmbi.1995.0318  0.346
1994 Rada C, González-Fernández A, Jarvis JM, Milstein C. The 5' boundary of somatic hypermutation in a V kappa gene is in the leader intron. European Journal of Immunology. 24: 1453-7. PMID 8206104 DOI: 10.1002/Eji.1830240632  0.344
1994 Foote J, Milstein C. Conformational isomerism and the diversity of antibodies. Proceedings of the National Academy of Sciences of the United States of America. 91: 10370-4. PMID 7937957 DOI: 10.1073/Pnas.91.22.10370  0.35
1994 Lozano F, Maertzdorf B, Pannell R, Milstein C. Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing. The Embo Journal. 13: 4617-22. PMID 7925302 DOI: 10.1002/J.1460-2075.1994.Tb06783.X  0.322
1994 González-Fernández A, Gupta SK, Pannell R, Neuberger MS, Milstein C. Somatic mutation of immunoglobulin lambda chains: a segment of the major intron hypermutates as much as the complementarity-determining regions. Proceedings of the National Academy of Sciences of the United States of America. 91: 12614-8. PMID 7809087 DOI: 10.1073/Pnas.91.26.12614  0.339
1993 Lozano F, Rada C, Jarvis JM, Milstein C. Affinity maturation leads to differential expression of multiple copies of a kappa light-chain transgene. Nature. 363: 271-3. PMID 8487865 DOI: 10.1038/363271A0  0.39
1993 Betz AG, Rada C, Pannell R, Milstein C, Neuberger MS. Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots. Proceedings of the National Academy of Sciences of the United States of America. 90: 2385-8. PMID 8460148 DOI: 10.1073/Pnas.90.6.2385  0.382
1993 Betz AG, Neuberger MS, Milstein C. Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes. Immunology Today. 14: 405-11. PMID 8397780 DOI: 10.1016/0167-5699(93)90144-A  0.333
1993 González-Fernández A, Milstein C. Analysis of somatic hypermutation in mouse Peyer's patches using immunoglobulin kappa light-chain transgenes. Proceedings of the National Academy of Sciences of the United States of America. 90: 9862-6. PMID 8234326 DOI: 10.1073/Pnas.90.21.9862  0.353
1993 Yu CY, Wu LC, Buluwela L, Milstein C. Cosmid cloning and walking to map human CD1 leukocyte differentiation antigen genes. Methods in Enzymology. 217: 378-98. PMID 7682646 DOI: 10.1016/0076-6879(93)17078-J  0.423
1992 Pannell R, Milstein C. An oscillating bubble chamber for laboratory scale production of monoclonal antibodies as an alternative to ascitic tumours. Journal of Immunological Methods. 146: 43-8. PMID 1735780 DOI: 10.1016/0022-1759(92)90046-V  0.326
1992 Gherardi E, Milstein C. Original and artificial antibodies. Nature. 357: 201-2. PMID 1589019 DOI: 10.1038/357201A0  0.332
1991 Milstein C. Affinity maturation of antibodies. Immunology Today. 12: 93-4. PMID 2059308 DOI: 10.1016/0167-5699(91)90164-O  0.337
1991 Dreher ML, Gherardi E, Skerra A, Milstein C. Colony assays for antibody fragments expressed in bacteria. Journal of Immunological Methods. 139: 197-205. PMID 2045660 DOI: 10.1016/0022-1759(91)90189-M  0.368
1991 Winter G, Milstein C. Man-made antibodies. Nature. 349: 293-9. PMID 1987490 DOI: 10.1038/349293A0  0.325
1991 Valetti C, Grossi CE, Milstein C, Sitia R. Russell bodies: a general response of secretory cells to synthesis of a mutant immunoglobulin which can neither exit from, nor be degraded in, the endoplasmic reticulum. The Journal of Cell Biology. 115: 983-94. PMID 1955467 DOI: 10.1083/Jcb.115.4.983  0.346
1991 Foote J, Milstein C. Kinetic maturation of an immune response. Nature. 352: 530-2. PMID 1907716 DOI: 10.1038/352530A0  0.34
1991 Rada C, Gupta SK, Gherardi E, Milstein C. Mutation and selection during the secondary response to 2-phenyloxazolone. Proceedings of the National Academy of Sciences of the United States of America. 88: 5508-12. PMID 1905811 DOI: 10.1073/Pnas.88.13.5508  0.322
1991 Bilsland CA, Milstein C. The identification of the beta 2-microglobulin binding antigen encoded by the human CD1D gene. European Journal of Immunology. 21: 71-8. PMID 1703966 DOI: 10.1002/Eji.1830210112  0.365
1990 Gherardi E, Pannell R, Milstein C. A single-step procedure for cloning and selection of antibody-secreting hybridomas. Journal of Immunological Methods. 126: 61-8. PMID 2303725 DOI: 10.1016/0022-1759(90)90012-K  0.37
1990 Alberini CM, Bet P, Milstein C, Sitia R. Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents. Nature. 347: 485-7. PMID 2120591 DOI: 10.1038/347485A0  0.336
1990 Sharpe MJ, Neuberger M, Pannell R, Surani MA, Milstein C. Lack of somatic mutation in a kappa light chain transgene. European Journal of Immunology. 20: 1379-85. PMID 2115000 DOI: 10.1002/Eji.1830200625  0.334
1990 Sitia R, Neuberger M, Alberini C, Bet P, Fra A, Valetti C, Williams G, Milstein C. Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine. Cell. 60: 781-90. PMID 2107027 DOI: 10.1016/0092-8674(90)90092-S  0.364
1990 Milstein C. The Croonian lecture, 1989. Antibodies: a paradigm for the biology of molecular recognition. Proceedings of the Royal Society of London. Series B, Biological Sciences. 239: 1-16. PMID 1968645 DOI: 10.1098/Rspb.1990.0006  0.339
1990 Bradbury A, Calabi F, Milstein C. Expression of CD1 in the mouse thymus. European Journal of Immunology. 20: 1831-6. PMID 1698634 DOI: 10.1002/Eji.1830200830  0.318
1989 Argon Y, Burkhardt JK, Leeds JM, Milstein C. Two steps in the intracellular transport of IgD are sensitive to energy depletion. Journal of Immunology (Baltimore, Md. : 1950). 142: 554-61. PMID 2911010  0.586
1989 Yu CY, Milstein C. A physical map linking the five CD1 human thymocyte differentiation antigen genes. The Embo Journal. 8: 3727-32. PMID 2583117 DOI: 10.1002/J.1460-2075.1989.Tb08548.X  0.499
1989 Calabi F, Belt KT, Yu CY, Bradbury A, Mandy WJ, Milstein C. The rabbit CD1 and the evolutionary conservation of the CD1 gene family. Immunogenetics. 30: 370-7. PMID 2478462 DOI: 10.1007/Bf02425277  0.482
1988 Verhoeyen M, Milstein C, Winter G. Reshaping human antibodies: grafting an antilysozyme activity. Science (New York, N.Y.). 239: 1534-6. PMID 2451287 DOI: 10.1126/Science.2451287  0.355
1987 Milstein C. Diversity and the genesis of high affinity antibodies. Biochemical Society Transactions. 15: 779-87. PMID 3691946 DOI: 10.1042/Bst0150779  0.324
1987 Díaz-Espada F, Milstein C, Secher D. The regulation of membrane-bound and secreted immunoglobulins in the human lymphoid cell line LICR-LON and human hybridomas. Molecular Immunology. 24: 595-603. PMID 3657799 DOI: 10.1016/0161-5890(87)90040-X  0.349
1987 Sitia R, Neuberger MS, Milstein C. Regulation of membrane IgM expression in secretory B cells: translational and post-translational events. The Embo Journal. 6: 3969-77. PMID 3127200 DOI: 10.1002/J.1460-2075.1987.Tb02739.X  0.361
1987 Berek C, Jarvis JM, Milstein C. Activation of memory and virgin B cell clones in hyperimmune animals. European Journal of Immunology. 17: 1121-9. PMID 3113977 DOI: 10.1002/Eji.1830170808  0.342
1987 Martin LH, Calabi F, Lefebvre FA, Bilsland CA, Milstein C. Structure and expression of the human thymocyte antigens CD1a, CD1b, and CD1c. Proceedings of the National Academy of Sciences of the United States of America. 84: 9189-93. PMID 2447586 DOI: 10.1073/Pnas.84.24.9189  0.362
1986 Martin LH, Calabi F, Milstein C. Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens. Proceedings of the National Academy of Sciences of the United States of America. 83: 9154-8. PMID 3097645 DOI: 10.1073/Pnas.83.23.9154  0.307
1986 Diaz-Espada F, Milstein C, Secher D. Effect of purified human interferon-alpha on the expression of differentiation antigens and mitogen reactivity of cultured human thymic cells. Cellular Immunology. 100: 331-9. PMID 2944603 DOI: 10.1016/0008-8749(86)90033-X  0.327
1985 Burrone OR, Kefford RF, Gilmore D, Milstein C. Stimulation of HLA-A,B,C by IFN-alpha. The derivation of Molt 4 variants and the differential expression of HLA-A,B,C subsets. The Embo Journal. 4: 2855-60. PMID 3864639 DOI: 10.1002/J.1460-2075.1985.Tb04014.X  0.312
1985 Milstein C. From the Structure of Antibodies to the Diversification of the Immune Responce (Noble Lecture) Angewandte Chemie International Edition in English. 24: 816-826. DOI: 10.1002/Anie.198508161  0.306
1984 Milstein C, Cuello AC. Hybrid hybridomas and the production of bi-specific monoclonal antibodies. Immunology Today. 5: 299-304. PMID 25290548 DOI: 10.1016/0167-5699(84)90155-5  0.35
1984 Griffiths GM, Berek C, Kaartinen M, Milstein C. Somatic mutation and the maturation of immune response to 2-phenyl oxazolone. Nature. 312: 271-5. PMID 6504141 DOI: 10.1038/312271A0  0.343
1984 Argon Y, Milstein C. Intracellular processing of membrane and secreted immunoglobulin delta-chains. Journal of Immunology (Baltimore, Md. : 1950). 133: 1627-34. PMID 6431004  0.589
1984 Kefford RF, Calabi F, Fearnley IM, Burrone OR, Milstein C. Serum beta 2-microglobulin binds to a T-cell differentiation antigen and increases its expression. Nature. 308: 641-2. PMID 6424030 DOI: 10.1038/308641A0  0.304
1984 Cuello AC, Milstein C, Couture R, Wright B, Priestley JV, Jarvis J. Characterization and immunocytochemical application of monoclonal antibodies against enkephalins. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 32: 947-57. PMID 6086744 DOI: 10.1177/32.9.6086744  0.347
1983 Burrone OR, Calabi F, Kefford RF, Milstein C. Somatic variants of the level of expression of a cell surface antigen. The Embo Journal. 2: 1591-5. PMID 11892817 DOI: 10.1002/J.1460-2075.1983.Tb01629.X  0.316
1983 Kaartinen M, Griffiths GM, Markham AF, Milstein C. mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification. Nature. 304: 320-4. PMID 6877353 DOI: 10.1038/304320A0  0.34
1983 Argon Y, Burrone OR, Milstein C. Molecular characterization of a nonsecreting myeloma mutant. European Journal of Immunology. 13: 301-5. PMID 6406235 DOI: 10.1002/Eji.1830130406  0.636
1983 Milstein C, Wright B, Cuello AC. The discrepancy between the cross-reactivity of a monoclonal antibody to serotonin and its immunohistochemical specificity. Molecular Immunology. 20: 113-23. PMID 6190077 DOI: 10.1016/0161-5890(83)90110-4  0.327
1982 Milstein C. Monoclonal antibodies. Cancer. 49: 1953-7. PMID 6176307 DOI: 10.1002/1097-0142(19820515)49:10<1953::Aid-Cncr2820491002>3.0.Co;2-H  0.333
1982 Burrone OR, Milstein C. The effect of interferon on the expression of human cell-surface antigens. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 299: 133-5. PMID 6128750 DOI: 10.1098/Rstb.1982.0116  0.354
1981 Milstein C. 12th Sir Hans Krebs Lecture. From antibody diversity to monoclonal antibodies. European Journal of Biochemistry / Febs. 118: 429-36. PMID 7297554 DOI: 10.1111/J.1432-1033.1981.Tb05538.X  0.326
1981 Consolazione A, Milstein C, Wright B, Cuello AC. Immunocytochemical detection of serotonin with monoclonal antibodies. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 29: 1425-30. PMID 7033368 DOI: 10.1177/29.12.7033368  0.339
1981 Milstein C. The Wellcome Foundation Lecture, 1980: monoclonal antibodies from hybrid myelomas. Proceedings of the Royal Society of London. Series B, Biological Sciences. 211: 393-412. PMID 6112754 DOI: 10.1098/Rspb.1981.0014  0.353
1980 Takei F, Galfrè G, Alderson T, Lennox ES, Milstein C. H 9/25 monoclonal antibody recognizes a new allospecificity of mouse lymphocyte subpopulations: strain and tissue distribution. European Journal of Immunology. 10: 241-6. PMID 7398756 DOI: 10.1002/Eji.1830100404  0.35
1980 Voak D, Sacks S, Alderson T, Takei F, Lennox E, Jarvis J, Milstein C, Darnborough J. Monoclonal anti-A from a hybrid-myeloma: evaluating as a blood grouping reagent. Vox Sanguinis. 39: 134-40. PMID 7210604 DOI: 10.1111/J.1423-0410.1980.Tb01848.X  0.349
1980 Bradstock KF, Janossy G, Pizzolo G, Hoffbrand AV, McMichael A, Pilch JR, Milstein C, Beverley P, Bollum FJ. Subpopulations of normal and leukemic human thymocytes: an analysis with the use of monoclonal antibodies. Journal of the National Cancer Institute. 65: 33-42. PMID 6993744 DOI: 10.1093/Jnci/65.1.33  0.333
1980 Bradstock KF, Janossy G, Bollum FJ, Milstein C. Anomalous phenotype in thymic acute lymphoblastic leukaemia. Nature. 284: 455-7. PMID 6928507 DOI: 10.1038/284455A0  0.308
1980 Takei F, Waldmann H, Lennox ES, Milstein C. Monoclonal antibody H9/25 reacts with functional subsets of T and B cells: killer, killer precursor and plaque-forming cells. European Journal of Immunology. 10: 503-9. PMID 6447609 DOI: 10.1002/Eji.1830100704  0.312
1980 Algranati ID, Milstein C, Ziegler A. Studies on biosynthesis, assembly and expression of human major transplantation antigens. European Journal of Biochemistry / Febs. 103: 197-207. PMID 6153612 DOI: 10.1111/J.1432-1033.1980.Tb04304.X  0.343
1980 Wilde CD, Milstein C. Analysis of immunoglobulin chain secretion using hybrid myelomas European Journal of Immunology. 10: 462-467. DOI: 10.1002/Eji.1830100611  0.343
1979 Howard JC, Butcher GW, Galfrè G, Milstein C, Milstein CP. Monoclonal antibodies as tools to analyze the serological and genetic complexities of major transplantation antigens. Immunological Reviews. 47: 139-74. PMID 398325 DOI: 10.1111/J.1600-065X.1979.Tb00292.X  0.307
1979 Ziegler A, Milstein C. A small polypeptide different from beta2-microglobin associated with a human cell surface antigen. Nature. 279: 243-4. PMID 312466 DOI: 10.1038/279243A0  0.364
1979 Springer T, Galfré G, Secher DS, Milstein C. Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. European Journal of Immunology. 9: 301-6. PMID 89034 DOI: 10.1002/Eji.1830090410  0.508
1979 Milstein C, Galfre G, Secher DS, Springer T. Monoclonal antibodies and cell surface antigens. Cell Biology International Reports. 3: 1-16. PMID 88272 DOI: 10.1016/0309-1651(79)90063-8  0.509
1978 Springer T, Galfre G, Secher D, Milstein C. Monoclonal xenogeneic antibodies to mouse leukocyte antigens: identification of macrophage-specific and other differentiation antigens. Current Topics in Microbiology and Immunology. 81: 45-50. PMID 688760 DOI: 10.1007/978-3-642-67448-8_7  0.462
1978 Adetugbo K, Milstein C. Spontaneous somatic frameshift mutation in a mouse myeloma. Journal of Molecular Biology. 121: 239-54. PMID 660653 DOI: 10.1016/S0022-2836(78)80007-2  0.361
1978 Milstein C, Adetugbo K, Cowan NJ, Kohler G, Secher DS. Expression of antibody genes in tissue culture: structural mutants and hybrid cells. National Cancer Institute Monograph. 321-30. PMID 107455  0.552
1978 Springer T, Galfrè G, Secher DS, Milstein C. Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens. European Journal of Immunology. 8: 539-51. PMID 81133 DOI: 10.1002/eji.1830080802  0.485
1977 Adetugbo K, Milstein C. Spontaneous missense mutation of an immunoglobulin in a mouse myeloma cell line. Journal of Molecular Biology. 115: 75-90. PMID 411937 DOI: 10.1016/0022-2836(77)90247-9  0.355
1977 Secher DS, Milstein C, Adetugbo K. Somatic mutants and antibody diversity. Immunological Reviews. 36: 51-72. PMID 408265 DOI: 10.1111/J.1600-065X.1977.Tb00382.X  0.337
1977 Milstein C, Adetugbo K, Cowan NJ, Köhler G, Secher DS, Wilde CD. Somatic cell genetics of antibody-secreting cells: studies of clonal diversification and analysis by cell fusion. Cold Spring Harbor Symposia On Quantitative Biology. 41: 793-803. PMID 408078  0.512
1977 Williams AF, Galfrè G, Milstein C. Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes. Cell. 12: 663-73. PMID 303545 DOI: 10.1016/0092-8674(77)90266-5  0.376
1977 WILDE CD, MILSTEIN C, KÖHLER G. Clonal Diversification of Antibody-Producing Cells in Culture Biochemical Society Transactions. 5: 33-33. DOI: 10.1042/Bst0050033B  0.328
1976 Cowan NJ, Secher DS, Milstein C. Purification and sequence analysis of the mRNA coding for an immunoglobulin heavy chain. European Journal of Biochemistry / Febs. 61: 353-68. PMID 813996 DOI: 10.1111/J.1432-1033.1976.Tb10029.X  0.568
1975 Adetugbo K, Poskus E, Svasti J, Milstein C. Mouse immunoglobulin subclasses: cyanogen bromide fragments and partial sequence of a gamma1 chain. European Journal of Biochemistry / Febs. 56: 503-19. PMID 809278 DOI: 10.1111/J.1432-1033.1975.Tb02256.X  0.537
1975 Rabbitts TH, Milstein C. Mouse immunoglobulin genes: studies on the reiteration frequency of light-chain genes by hybridisation procedures. European Journal of Biochemistry / Febs. 52: 125-33. PMID 51793 DOI: 10.1111/J.1432-1033.1975.Tb03980.X  0.302
1974 Cowan NJ, Milstein C. Stability of cytoplasmic ribonucleic acid in a mouse myeloma: estimation of the half-life of the messenger RNA coding for an immunoglobulin light chain. Journal of Molecular Biology. 82: 469-81. PMID 4817791 DOI: 10.1016/0022-2836(74)90242-3  0.488
1974 Milstein C, Brownlee GG, Cartwright EM, Jarvis JM, Proudfoot NJ. Sequence analysis of immunoglobulin light chain messenger RNA. Nature. 252: 354-9. PMID 4473725 DOI: 10.1038/252354A0  0.32
1974 Cowan NJ, Secher DS, Milstein C. Intracellular immunoglobulin chain synthesis in non-secreting variants of a mouse myeloma: detection of inactive light-chain messenger RNA. Journal of Molecular Biology. 90: 691-701. PMID 4449137 DOI: 10.1016/0022-2836(74)90533-6  0.522
1973 Cowan NJ, Secher DS, Cotton RG, Milstein C. The secretion of a sialic acid-free immunoglobulin. Febs Letters. 30: 343-6. PMID 4735599 DOI: 10.1016/0014-5793(73)80684-2  0.462
1973 Cowan NJ, Milstein C. The translation in vitro of mRNA for immunoglobulin heavy chains. European Journal of Biochemistry / Febs. 36: 1-7. PMID 4732916 DOI: 10.1111/J.1432-1033.1973.Tb02877.X  0.591
1973 Brownlee GG, Cartwright EM, Cowan NJ, Jarvis JM, Milstein C. Purification and sequence of messenger RNA for immunoglobulin light chains. Nature: New Biology. 244: 236-40. PMID 4516600 DOI: 10.1038/Newbio244236A0  0.536
1972 Svasti J, Milstein C. The disulphide bridges of a mouse immunoglobulin G1 protein. The Biochemical Journal. 126: 837-50. PMID 5073237 DOI: 10.1042/Bj1260837  0.495
1972 Cowan NJ, Milstein C. Automatic monitoring of biochemical parameters in tissue culture. Studies on synchronously growing mouse myeloma cells. The Biochemical Journal. 128: 445-54. PMID 4673519  0.48
1972 Svasti J, Milstein C. The complete amino acid sequence of a mouse kappa light chain. The Biochemical Journal. 128: 427-44. PMID 4638343 DOI: 10.1042/Bj1280427  0.488
1972 Querinjean P, Bazin H, Beckers A, Deckers C, Heremans JF, Milstein C. Transplantable immunoglobulin-secreting tumours in rats. Purification and chemical characterization of four kappa chains from LOU-Wsl rats. European Journal of Biochemistry / Febs. 31: 354-9. PMID 4630505 DOI: 10.1111/J.1432-1033.1972.Tb02540.X  0.322
1972 Svasti J, Milstein C. The parallel nature of the interchain disulphide bonds of immunoglobulins. Studies on a mouse IgG1 myeloma protein. European Journal of Biochemistry / Febs. 31: 405-22. PMID 4568077 DOI: 10.1111/J.1432-1033.1972.Tb02547.X  0.544
1971 Milstein C, Frangione B. Disulphide bridges of the heavy chain of human immunoglobulin G2. The Biochemical Journal. 121: 217-25. PMID 4940472  0.472
1970 Svasti J, Milstein C. Interchain bridges of mouse IgG1. Nature. 228: 932-4. PMID 5529796 DOI: 10.1038/228932A0  0.548
1969 Frangione B, Milstein C, Pink JR. Structural studies of immunoglobulin G. Nature. 221: 145-8. PMID 5782707  0.361
1969 Frangione B, Milstein C, Franklin EC. Chemical typing of immunoglobulins. Nature. 221: 149-51. PMID 4882223  0.363
1969 Milstein C, Jarvis JM, Milstein CP. Occurrence of the Inv genetic markers in the subgroups of human kappa chains. Journal of Molecular Biology. 46: 599-602. PMID 4189139 DOI: 10.1016/0022-2836(69)90202-2  0.34
1969 Frangione B, Milstein C. Partial deletion in the heavy chain disease protein ZUC. Nature. 224: 597-9. PMID 4186690  0.425
1968 Frangione B, Milstein C, Franklin EC. Intrachain disulphide bridges in immunoglobulin G heavy chains. The Fc fragment. The Biochemical Journal. 106: 15-21. PMID 4889360  0.471
1968 Frangione B, Milstein C. Variations in the S-S bridges of immunoglobins G: interchain disulfide bridges of gamma G3 myeloma proteins. Journal of Molecular Biology. 33: 893-906. PMID 4178186 DOI: 10.1016/0022-2836(68)90326-4  0.527
1967 Cohen S, Milstein C. Structure of antibody molecules. Nature. 214: 449-52 passim. PMID 6032862 DOI: 10.1038/214449A0  0.393
1967 Cohen S, Milstein C. Structure and biological properties of immunoglobulins. Advances in Immunology. 7: 1-89. PMID 4171249 DOI: 10.1016/S0065-2776(08)60126-1  0.401
1967 Frangione B, Milstein C. Disulphide bridges of immunoglobin G-1 heavy chains. Nature. 216: 939-41. PMID 4169396  0.42
1967 Milstein C, Frangione B, Pink JRL. Studies on the Variability of Immunoglobulin Sequence Cold Spring Harbor Symposia On Quantitative Biology. 32: 31-36. DOI: 10.1101/SQB.1967.032.01.007  0.39
1966 Brenner S, Milstein C. Origin of antibody variation. Nature. 211: 242-3. PMID 5965537 DOI: 10.1038/211242A0  0.326
1966 Milstein C. Chemical structure of light chains. Proceedings of the Royal Society of London. Series B, Biological Sciences. 166: 138-49. PMID 4382708 DOI: 10.1098/Rspb.1966.0089  0.339
1958 MILSTEIN C, STOPPANI AO. Kinetics of the potassium-activated aldehyde dehydrogenase of yeast. Biochimica Et Biophysica Acta. 28: 218-9. PMID 13535710  0.592
1957 STOPPANI AO, MILSTEIN C. [Enzyme-substrate complexes of diphosphopyridine nucleotide-linked aldehyde dehydrogenase of yeast]. Revista De La Sociedad Argentina De BiologíA. 33: 289-304. PMID 13579649  0.596
1957 STOPPANI AO, MILSTEIN C. [Effect of acetaldehyde on inhibition of aldehydedehydrogenase by thio-reagents]. Comptes Rendus Des SéAnces De La SociéTé De Biologie Et De Ses Filiales. 151: 1751-2. PMID 13547602  0.59
1957 STOPPANI AO, MILSTEIN C. [Effect of acetaldehyde on inhibition of aldehyde dehydrogenases by thiol reactants]. Revista De La Sociedad Argentina De BiologíA. 33: 149-56. PMID 13528173  0.599
1957 STOPPANI AO, MILSTEIN C. [Effects of cations on sensitivity of aldehyde-dehydrogenase to sulfhydryl reagents]. Comptes Rendus Des SéAnces De La SociéTé De Biologie Et De Ses Filiales. 151: 1020-3. PMID 13500729  0.607
1957 STOPPANI AO, MILSTEIN C. [Influence of cations on the sensitivity of aldehyde dehydrogenases by thiol reagents]. Revista De La Sociedad Argentina De BiologíA. 33: 100-8. PMID 13485696  0.606
1957 STOPPANI AO, MILSTEIN C. [Specific protection by pyridine-adenine dinucleotides of essential thiols in aldehyde dehydrogenases]. Revista De La Sociedad Argentina De BiologíA. 33: 80-9. PMID 13485694  0.629
1957 STOPPANI AO, MILSTEIN C. Essential role of thiol groups in aldehyde dehydrogenases. The Biochemical Journal. 67: 406-16. PMID 13479397 DOI: 10.1042/Bj0670406  0.59
1957 STOPPANI AO, MILSTEIN C. Specific protection of the thiol groups of aldehyde dehydrogenases by pyridine-nucleotide coenzymes. Biochimica Et Biophysica Acta. 24: 655-7. PMID 13436502 DOI: 10.1016/0006-3002(57)90270-6  0.616
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