Paul F. Pilch - Publications

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Molecular Biology, Biochemistry

158 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang H, Pilch PF, Liu L. Cavin-1/PTRF mediates insulin-dependent focal adhesion remodeling and ameliorates high-fat diet-induced inflammatory responses in mice. The Journal of Biological Chemistry. PMID 31126986 DOI: 10.1074/jbc.RA119.008824  0.76
2018 Williams JJL, Alotaiq N, Mullen W, Burchmore R, Liu L, Baillie GS, Schaper F, Pilch PF, Palmer TM. Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability. Nature Communications. 9: 168. PMID 29330478 DOI: 10.1038/s41467-017-02585-y  0.76
2017 Ding SY, Liu L, Pilch PF. Muscular dystrophy in PTFR/cavin-1 null mice. Jci Insight. 2: e91023. PMID 28289716 DOI: 10.1172/jci.insight.91023  0.76
2016 Scheller EL, Doucette CR, Learman BS, Cawthorn WP, Khandaker S, Schell B, Wu B, Ding SY, Bredella MA, Fazeli PK, Khoury B, Jepsen KJ, Pilch PF, Klibanski A, Rosen CJ, et al. Corrigendum: Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues. Nature Communications. 7: 13775. PMID 27929114 DOI: 10.1038/ncomms13775  0.36
2016 Liu L, Pilch PF. PTRF/Cavin-1 promotes efficient ribosomal RNA transcription in response to metabolic challenges. Elife. 5. PMID 27528195 DOI: 10.7554/eLife.17508  0.76
2015 Jedrychowski MP, Liu L, Laflamme CJ, Karastergiou K, Meshulam T, Ding SY, Wu Y, Lee MJ, Gygi SP, Fried SK, Pilch PF. Adiporedoxin, an upstream regulator of ER oxidative folding and protein secretion in adipocytes. Molecular Metabolism. 4: 758-770. PMID 26629401 DOI: 10.1016/j.molmet.2015.09.002  1
2015 Lo HP, Nixon SJ, Hall TE, Cowling BS, Ferguson C, Morgan GP, Schieber NL, Fernandez-Rojo MA, Bastiani M, Floetenmeyer M, Martel N, Laporte J, Pilch PF, Parton RG. The caveolin-cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle. The Journal of Cell Biology. 210: 833-49. PMID 26323694 DOI: 10.1083/jcb.201501046  1
2015 Scheller EL, Doucette CR, Learman BS, Cawthorn WP, Khandaker S, Schell B, Wu B, Ding SY, Bredella MA, Fazeli PK, Khoury B, Jepsen KJ, Pilch PF, Klibanski A, Rosen CJ, et al. Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues. Nature Communications. 6: 7808. PMID 26245716 DOI: 10.1038/ncomms8808  1
2014 Liu L, Hansen CG, Honeyman BJ, Nichols BJ, Pilch PF. Cavin-3 knockout mice show that cavin-3 is not essential for caveolae formation, for maintenance of body composition, or for glucose tolerance. Plos One. 9: e102935. PMID 25036884 DOI: 10.1371/journal.pone.0102935  1
2014 Ding SY, Lee MJ, Summer R, Liu L, Fried SK, Pilch PF. Pleiotropic effects of cavin-1 deficiency on lipid metabolism. The Journal of Biological Chemistry. 289: 8473-83. PMID 24509860 DOI: 10.1074/jbc.M113.546242  1
2013 Fernández-Rojo MA, Gongora M, Fitzsimmons RL, Martel N, Martin SD, Nixon SJ, Brooks AJ, Ikonomopoulou MP, Martin S, Lo HP, Myers SA, Restall C, Ferguson C, Pilch PF, McGee SL, et al. Caveolin-1 is necessary for hepatic oxidative lipid metabolism: evidence for crosstalk between caveolin-1 and bile acid signaling. Cell Reports. 4: 238-47. PMID 23850288 DOI: 10.1016/j.celrep.2013.06.017  1
2013 Scotti E, Calamai M, Goulbourne CN, Zhang L, Hong C, Lin RR, Choi J, Pilch PF, Fong LG, Zou P, Ting AY, Pavone FS, Young SG, Tontonoz P. IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor. Molecular and Cellular Biology. 33: 1503-14. PMID 23382078 DOI: 10.1128/MCB.01716-12  1
2012 Hill MM, Daud NH, Aung CS, Loo D, Martin S, Murphy S, Black DM, Barry R, Simpson F, Liu L, Pilch PF, Hancock JF, Parat MO, Parton RG. Co-regulation of cell polarization and migration by caveolar proteins PTRF/Cavin-1 and caveolin-1. Plos One. 7: e43041. PMID 22912783 DOI: 10.1371/journal.pone.0043041  1
2012 Breen MR, Camps M, Carvalho-Simoes F, Zorzano A, Pilch PF. Cholesterol depletion in adipocytes causes caveolae collapse concomitant with proteosomal degradation of cavin-2 in a switch-like fashion. Plos One. 7: e34516. PMID 22493697 DOI: 10.1371/journal.pone.0034516  0.56
2012 Tkachenko E, Tse D, Sideleva O, Deharvengt SJ, Luciano MR, Xu Y, McGarry CL, Chidlow J, Pilch PF, Sessa WC, Toomre DK, Stan RV. Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells. Plos One. 7: e32655. PMID 22403691 DOI: 10.1371/journal.pone.0032655  1
2012 Breen MR, Camps M, Carvalho-Simoes F, Zorzano A, Pilch PF. Cholesterol depletion in adipocytes causes caveolae collapse concomitant with proteosomal degradation of cavin-2 in a switch-like fashion Plos One. 7. DOI: 10.1371/journal.pone.0034516  1
2011 Meshulam T, Breen MR, Liu L, Parton RG, Pilch PF. Caveolins/caveolae protect adipocytes from fatty acid-mediated lipotoxicity. Journal of Lipid Research. 52: 1526-32. PMID 21652731 DOI: 10.1194/jlr.M015628  1
2011 Pilch PF, Meshulam T, Ding S, Liu L. Caveolae and lipid trafficking in adipocytes. Clinical Lipidology. 6: 49-58. PMID 21625349 DOI: 10.2217/clp.10.80  1
2011 Pilch PF, Liu L. Fat caves: caveolae, lipid trafficking and lipid metabolism in adipocytes. Trends in Endocrinology and Metabolism: Tem. 22: 318-24. PMID 21592817 DOI: 10.1016/j.tem.2011.04.001  1
2011 Kandror KV, Pilch PF. The sugar is sIRVed: sorting Glut4 and its fellow travelers. Traffic (Copenhagen, Denmark). 12: 665-71. PMID 21306486 DOI: 10.1111/j.1600-0854.2011.01175.x  1
2010 Simard JR, Meshulam T, Pillai BK, Kirber MT, Brunaldi K, Xu S, Pilch PF, Hamilton JA. Caveolins sequester FA on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation, and protect cells from lipotoxicity. Journal of Lipid Research. 51: 914-22. PMID 20388923 DOI: 10.1194/jlr.M900251  0.4
2010 Jedrychowski MP, Gartner CA, Gygi SP, Zhou L, Herz J, Kandror KV, Pilch PF. Proteomic analysis of GLUT4 storage vesicles reveals LRP1 to be an important vesicle component and target of insulin signaling. The Journal of Biological Chemistry. 285: 104-14. PMID 19864425 DOI: 10.1074/jbc.M109.040428  1
2009 Chao LC, Wroblewski K, Zhang Z, Pei L, Vergnes L, Ilkayeva OR, Ding SY, Reue K, Watt MJ, Newgard CB, Pilch PF, Hevener AL, Tontonoz P. Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77. Diabetes. 58: 2788-96. PMID 19741162 DOI: 10.2337/db09-0763  1
2009 Bastiani M, Liu L, Hill MM, Jedrychowski MP, Nixon SJ, Lo HP, Abankwa D, Luetterforst R, Fernandez-Rojo M, Breen MR, Gygi SP, Vinten J, Walser PJ, North KN, Hancock JF, ... Pilch PF, et al. MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes. The Journal of Cell Biology. 185: 1259-73. PMID 19546242 DOI: 10.1083/jcb.200903053  1
2008 Liu L, Brown D, McKee M, Lebrasseur NK, Yang D, Albrecht KH, Ravid K, Pilch PF. Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell Metabolism. 8: 310-7. PMID 18840361 DOI: 10.1016/j.cmet.2008.07.008  1
2008 Pilch PF. The mass action hypothesis: Formation of Glut4 storage vesicles, a tissue-specific, regulated exocytic compartment Acta Physiologica. 192: 89-101. PMID 18171432 DOI: 10.1111/j.1748-1716.2007.01788.x  1
2008 Liu L, Pilch PF. A critical role of cavin (polymerase I and transcript release factor) in caveolae formation and organization. The Journal of Biological Chemistry. 283: 4314-22. PMID 18056712 DOI: 10.1074/jbc.M707890200  1
2007 Saito T, Jones CC, Huang S, Czech MP, Pilch PF. The interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocation. The Journal of Biological Chemistry. 282: 32280-7. PMID 17848569 DOI: 10.1074/jbc.M704150200  1
2007 Chao LC, Zhang Z, Pei L, Saito T, Tontonoz P, Pilch PF. Nur77 coordinately regulates expression of genes linked to glucose metabolism in skeletal muscle. Molecular Endocrinology (Baltimore, Md.). 21: 2152-63. PMID 17550977 DOI: 10.1210/me.2007-0169  1
2007 Coderre L, Vallega GA, Pilch PF, Chipkin SR. Regulation of glycogen concentration and glycogen synthase activity in skeletal muscle of insulin-resistant rats. Archives of Biochemistry and Biophysics. 464: 144-50. PMID 17509520 DOI: 10.1016/j.abb.2007.04.012  1
2007 Pilch PF, Souto RP, Liu L, Jedrychowski MP, Berg EA, Costello CE, Gygi SP. Cellular spelunking: exploring adipocyte caveolae. Journal of Lipid Research. 48: 2103-11. PMID 17496267 DOI: 10.1194/jlr.R700009-JLR200  1
2006 Kandror KV, Pilch PF. Isolation of GLUT4 storage vesicles. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 3.20. PMID 18228488 DOI: 10.1002/0471143030.cb0320s30  1
2006 Liu L, Jedrychowski MP, Gygi SP, Pilch PF. Role of insulin-dependent cortical fodrin/spectrin remodeling in glucose transporter 4 translocation in rat adipocytes. Molecular Biology of the Cell. 17: 4249-56. PMID 16870704 DOI: 10.1091/mbc.E06-04-0278  1
2006 Pilch PF, Bergenhem N. Pharmacological targeting of adipocytes/fat metabolism for treatment of obesity and diabetes. Molecular Pharmacology. 70: 779-85. PMID 16760360 DOI: 10.1124/mol.106.026104  1
2006 Meshulam T, Simard JR, Wharton J, Hamilton JA, Pilch PF. Role of caveolin-1 and cholesterol in transmembrane fatty acid movement. Biochemistry. 45: 2882-93. PMID 16503643 DOI: 10.1021/bi051999b  0.4
2006 Gross DN, Miyoshi H, Hosaka T, Zhang HH, Pino EC, Souza S, Obin M, Greenberg AS, Pilch PF. Dynamics of lipid droplet-associated proteins during hormonally stimulated lipolysis in engineered adipocytes: stabilization and lipid droplet binding of adipocyte differentiation-related protein/adipophilin. Molecular Endocrinology (Baltimore, Md.). 20: 459-66. PMID 16239256 DOI: 10.1210/me.2005-0323  1
2005 Hosaka T, Brooks CC, Presman E, Kim SK, Zhang Z, Breen M, Gross DN, Sztul E, Pilch PF. p115 Interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation. Molecular Biology of the Cell. 16: 2882-90. PMID 15800058 DOI: 10.1091/mbc.E05-01-0072  1
2004 Gross DN, Farmer SR, Pilch PF. Glut4 storage vesicles without Glut4: transcriptional regulation of insulin-dependent vesicular traffic. Molecular and Cellular Biology. 24: 7151-62. PMID 15282314 DOI: 10.1128/MCB.24.16.7151-7162.2004  1
2003 Tortorella LL, Lin CB, Pilch PF. ERK6 is expressed in a developmentally regulated manner in rodent skeletal muscle. Biochemical and Biophysical Research Communications. 306: 163-8. PMID 12788083 DOI: 10.1016/S0006-291X(03)00936-7  1
2003 Tojo H, Kaieda I, Hattori H, Katayama N, Yoshimura K, Kakimoto S, Fujisawa Y, Presman E, Brooks CC, Pilch PF. The Formin family protein, formin homolog overexpressed in spleen, interacts with the insulin-responsive aminopeptidase and profilin IIa. Molecular Endocrinology (Baltimore, Md.). 17: 1216-29. PMID 12677009 DOI: 10.1210/me.2003-0056  1
2003 Souto RP, Vallega G, Wharton J, Vinten J, Tranum-Jensen J, Pilch PF. Immunopurification and characterization of rat adipocyte caveolae suggest their dissociation from insulin signaling. The Journal of Biological Chemistry. 278: 18321-9. PMID 12637562 DOI: 10.1074/jbc.M211541200  1
2003 Botchkarev VA, Yaar M, Gilchrest BA, Paus R. p75 Neurotrophin receptor antagonist retards apoptosis-driven hair follicle involution (catagen). The Journal of Investigative Dermatology. 120: 168-9. PMID 12535214 DOI: 10.1046/j.1523-1747.2003.12003.x  1
2002 Tortorella LL, Pilch PF. C2C12 myocytes lack an insulin-responsive vesicular compartment despite dexamethasone-induced GLUT4 expression. American Journal of Physiology. Endocrinology and Metabolism. 283: E514-24. PMID 12169445 DOI: 10.1152/ajpendo.00092.2002  1
2001 Tortorella LL, Milasincic DJ, Pilch PF. Critical proliferation-independent window for basic fibroblast growth factor repression of myogenesis via the p42/p44 MAPK signaling pathway. The Journal of Biological Chemistry. 276: 13709-17. PMID 11279003 DOI: 10.1074/jbc.M100091200  1
2000 Martinez C, Vallega G, Pilch PF. Insulin-dependent phosphorylation of a 70-kDa protein in light microsomes from rat adipocytes Biochemical and Biophysical Research Communications. 276: 1302-1305. PMID 11027626 DOI: 10.1006/bbrc.2000.3612  1
2000 Zhou M, Lin BZ, Coughlin S, Vallega G, Pilch PF. UCP-3 expression in skeletal muscle: effects of exercise, hypoxia, and AMP-activated protein kinase. American Journal of Physiology. Endocrinology and Metabolism. 279: E622-9. PMID 10950831  1
2000 Liu H, Kublaoui B, Pilch PF, Lee J. Insulin activation of mitogen-activated protein (MAP) kinase and AKT is phosphatidylinositol 3-kinase-dependent in rat adipocytes Biochemical and Biophysical Research Communications. 274: 845-851. PMID 10924365 DOI: 10.1006/bbrc.2000.3208  1
2000 Zhou M, Vallega G, Kandror KV, Pilch PF. Insulin-mediated translocation of GLUT-4-containing vesicles is preserved in denervated muscles American Journal of Physiology - Endocrinology and Metabolism. 278. PMID 10827003  1
2000 Calera MR, Vallega G, Pilch PF. Dynamics of protein-tyrosine phosphatases in rat adipocytes Journal of Biological Chemistry. 275: 6308-6312. PMID 10692429 DOI: 10.1074/jbc.275.9.6308  1
1999 Hamm JK, el Jack AK, Pilch PF, Farmer SR. Role of PPAR gamma in regulating adipocyte differentiation and insulin-responsive glucose uptake. Annals of the New York Academy of Sciences. 892: 134-45. PMID 10842659  1
1999 Lee W, Ryu J, Souto RP, Pilch PF, Jung CY. Separation and partial characterization of three distinct intracellular GLUT4 compartments in rat adipocytes. Subcellular fractionation without homogenization Journal of Biological Chemistry. 274: 37755-37762. PMID 10608836 DOI: 10.1074/jbc.274.53.37755  1
1999 Woldin CN, Hing FS, Lee J, Pilch PF, Shipley GG. Structural studies of the detergent-solubilized and vesicle- reconstituted insulin receptor Journal of Biological Chemistry. 274: 34981-34992. PMID 10574975 DOI: 10.1074/jbc.274.49.34981  1
1999 El-Jack AK, Kandror KV, Pilch PF. The formation of an insulin-responsive vesicular cargo compartment is an early event in 3T3-L1 adipocyte differentiation. Molecular Biology of the Cell. 10: 1581-94. PMID 10233164  1
1999 El-Jack AK, Hamm JK, Pilch PF, Farmer SR. Reconstitution of insulin-sensitive glucose transport in fibroblasts requires expression of both PPARgamma and C/EBPalpha. The Journal of Biological Chemistry. 274: 7946-51. PMID 10075691 DOI: 10.1074/jbc.274.12.7946  1
1998 Calera MR, Pilch PF. Induction of Akt-2 correlates with differentiation in Sol8 muscle cells Biochemical and Biophysical Research Communications. 251: 835-841. PMID 9790996 DOI: 10.1006/bbrc.1998.9566  1
1998 Cushman SW, Goodyear LJ, Pilch PF, Ralston E, Galbo H, Ploug T, Kristiansen S, Klip A. Molecular mechanisms involved in GLUT4 translocation in muscle during insulin and contraction stimulation Advances in Experimental Medicine and Biology. 441: 63-71. PMID 9781314  1
1998 Lin B, Coughlin S, Pilch PF. Bidirectional regulation of uncoupling protein-3 and GLUT-4 mRNA in skeletal muscle by cold. The American Journal of Physiology. 275: E386-91. PMID 9725803  1
1998 Zhou M, Sevilla L, Vallega G, Chen P, Palacin M, Zorzano A, Pilch PF, Kandror KV. Insulin-dependent protein trafficking in skeletal muscle cells American Journal of Physiology - Endocrinology and Metabolism. 275. PMID 9688618  1
1998 Kummer JL, Calera MR, Pilch PF. Separation of IRS-1 and PI3-kinase from GLUT4 vesicles in rat skeletal muscle Biochemical and Biophysical Research Communications. 246: 282-286. PMID 9600107 DOI: 10.1006/bbrc.1998.8599  1
1998 Kandror KV, Pilch PF. Multiple endosomal recycling pathways in rat adipose cells Biochemical Journal. 331: 829-835. PMID 9560311  1
1998 Calera MR, Martinez C, Liu H, Jack AK, Birnbaum MJ, Pilch PF. Insulin increases the association of Akt-2 with Glut4-containing vesicles. The Journal of Biological Chemistry. 273: 7201-4. PMID 9516411 DOI: 10.1074/jbc.273.13.7201  1
1997 Yaar M, Zhai S, Pilch PF, Doyle SM, Eisenhauer PB, Fine RE, Gilchrest BA. Binding of β-amyloid to the p75 neurotrophin receptor induces apoptosis: A possible mechanism for Alzheimer's disease Journal of Clinical Investigation. 100: 2333-2340. PMID 9410912  1
1997 Lin BZ, Pilch PF, Kandror KV. Sortilin is a major protein component of Glut4-containing vesicles Journal of Biological Chemistry. 272: 24145-24147. PMID 9305862 DOI: 10.1074/jbc.272.39.24145  1
1997 Lee J, Pilch PF, Shoelson SE, Scarlata SF. Conformational changes of the insulin receptor upon insulin binding and activation as monitored by fluorescence spectroscopy. Biochemistry. 36: 2701-8. PMID 9054578 DOI: 10.1021/bi961815g  1
1997 Stephens JM, Lee J, Pilch PF. Tumor necrosis factor-α-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction Journal of Biological Chemistry. 272: 971-976. PMID 8995390 DOI: 10.1074/jbc.272.2.971  1
1996 Coderre L, Vallega GA, Pilch PF, Chipkin SR. In vivo effects of dexamethasone and sucrose on glucose transport (GLUT- 4) protein tissue distribution American Journal of Physiology - Endocrinology and Metabolism. 271. PMID 8897851  1
1996 Milasincic DJ, Calera MR, Farmer SR, Pilch PF. Stimulation of C2C12 myoblast growth by basic fibroblast growth factor and insulin-like growth factor 1 can occur via mitogen-activated protein kinase-dependent and -independent pathways. Molecular and Cellular Biology. 16: 5964-73. PMID 8887626  1
1996 Kandror KV, Pilch PF. Compartmentalization of protein traffic in insulin-sensitive cells American Journal of Physiology - Endocrinology and Metabolism. 271. PMID 8760075  1
1996 Kandror KV, Pilch PF. The insulin-like growth factor II/mannose 6-phosphate receptor utilizes the same membrane compartments as GLUT4 for insulin-dependent trafficking to and from the rat adipocyte cell surface Journal of Biological Chemistry. 271: 21703-21708. PMID 8702963 DOI: 10.1074/jbc.271.36.21703  1
1996 Tozzo E, Kahn BB, Pilch PF, Kandror KV. Glut4 is targeted to specific vesicles in adipocytes of transgenic mice overexpressing Glut4 selectively in adipose tissue Journal of Biological Chemistry. 271: 10490-10494. PMID 8631845 DOI: 10.1074/jbc.271.18.10490  1
1996 Stephens JM, Morrison RF, Pilch PF. The expression and regulation of STATs during 3T3-L1 adipocyte differentiation Journal of Biological Chemistry. 271: 10441-10444. PMID 8631837 DOI: 10.1074/jbc.271.18.10441  1
1996 Kandror KV, Pilch PF. GLUT4-containing vesicles in rat adipocytes as a tissue-specific recycling compartment Seminars in Cell and Developmental Biology. 7: 269-278. DOI: 10.1006/scdb.1996.0035  1
1995 Lee J, Shoelson SE, Pilch PF. Intermolecular phosphorylation between insulin holoreceptors does not stimulate substrate kinase activity. The Journal of Biological Chemistry. 270: 31136-40. PMID 8537376 DOI: 10.1074/jbc.270.52.31136  1
1995 Munoz P, Rosemblatt M, Testar X, Palacin M, Thoidis G, Pilch PF, Zorzano A. The T-tubule is a cell-surface target for insulin-regulated recycling of membrane proteins in skeletal muscle Biochemical Journal. 312: 393-400. PMID 8526847  1
1995 Stephens JM, Pilch PF. The metabolic regulation and vesicular transport of GLUT4, the major insulin-responsive glucose transporter Endocrine Reviews. 16: 529-546. PMID 8521793  1
1995 Kublaoui B, Lee J, Pilch PF. Dynamics of signaling during insulin-stimulated endocytosis of its receptor in adipocytes Journal of Biological Chemistry. 270: 59-65. PMID 7814420 DOI: 10.1074/jbc.270.1.59  1
1995 Kandror KV, Stephens JM, Pilch PF. Expression and compartmentalization of caveolin in adipose cells: Coordinate regulation with and structural segregation from GLUT4 Journal of Cell Biology. 129: 999-1006. PMID 7744970  1
1995 Kandror KV, Coderre L, Pushkin AV, Pilch PF. Comparison of glucose-transporter-containing vesicles from rat fat and muscle tissues: Evidence for a unique endosomal compartment Biochemical Journal. 307: 383-390. PMID 7733873  1
1995 Coderre L, Kandror KV, Vallega G, Pilch PF. Identification and characterization of an exercise-sensitive pool of glucose transporters in skeletal muscle Journal of Biological Chemistry. 270: 27584-27588. PMID 7499220 DOI: 10.1074/jbc.270.46.27584  1
1994 Kandror K, Pilch PF. Identification and isolation of glycoproteins that translocate to the cell surface from GLUT4-enriched vesicles in an insulin-dependent fashion Journal of Biological Chemistry. 269: 138-142. PMID 8276787  1
1994 Lee J, Pilch PF. The insulin receptor: Structure, function, and signaling American Journal of Physiology - Cell Physiology. 266. PMID 8141246  1
1994 Kandror KV, Pilch PF. gp160, A tissue-specific marker for insulin-activated glucose transport Proceedings of the National Academy of Sciences of the United States of America. 91: 8017-8021. PMID 8058750 DOI: 10.1073/pnas.91.17.8017  1
1994 Kandror KV, Yu L, Pilch PF. The major protein of GLUT4-containing vesicles, gp160, has aminopeptidase activity Journal of Biological Chemistry. 269: 30777-30780. PMID 7983006  1
1993 Thoidis G, Kotliar N, Pilch PF. Immunological analysis of GLUT4-enriched vesicles: Identification of novel proteins regulated by insulin and diabetes Journal of Biological Chemistry. 268: 11691-11696. PMID 8505298  1
1993 Lee J, O'Hare T, Pilch PF, Shoelson SE. Insulin receptor autophosphorylation occurs asymmetrically. The Journal of Biological Chemistry. 268: 4092-8. PMID 8440700  1
1993 Shoelson SE, Lee J, Lynch CS, Backer JM, Pilch PF. BpaB25 insulins. Photoactivatable analogues that quantitatively cross-link, radiolabel, and activate the insulin receptor. The Journal of Biological Chemistry. 268: 4085-91. PMID 8382690  1
1993 Pilch PF, Wilkinson W, Garvey WT, Ciaraldi TP, Hueckstaedt TP, Olefsky JM. Insulin-responsive human adipocytes express two glucose transporter isoforms and target them to different vesicles Journal of Clinical Endocrinology and Metabolism. 77: 286-289. PMID 8325954  1
1992 Kotliar N, Pilch PF. Expression of the glucose transporter isoform GLUT 4 is insufficient to confer insulin-regulatable hexose uptake to cultured muscle cells Molecular Endocrinology. 6: 337-345. PMID 1584210 DOI: 10.1210/me.6.3.337  1
1992 Mischoulon D, Rana B, Kotliar N, Pilch PF, Bucher NLR, Farmer SR. Differential regulation of glucose transporter 1 and 2 mRNA expression by epidermal growth factor and transforming growth factor-beta in rat hepatocytes Journal of Cellular Physiology. 153: 288-296. PMID 1429849  1
1992 Coderre L, Monfar MM, Chen KS, Heydrick SJ, Kurowski TG, Ruderman NB, Pilch PF. Alteration in the expression of GLUT-1 and GLUT-4 protein and messenger RNA levels in denervated rat muscles Endocrinology. 131: 1821-1825. PMID 1396328  1
1991 Sinha MK, Raineri-Maldonado C, Buchanan C, Pories WJ, Carter-Su C, Pilch PF, Caro JF. Adipose tissue glucose transporters in NIDDM: Decreased levels of muscle/fat isoform Diabetes. 40: 472-477. PMID 2010047  1
1991 Dohm GL, Elton CW, Friedman JE, Pilch PF, Pories WJ, Atkinson SM, Caro JF. Decreased expression of glucose transporter in muscle from insulin-resistant patients. The American Journal of Physiology. 260: E459-63. PMID 2003599  1
1991 Del Vecchio RL, Pilch PF. Phosphatidylinositol 4-kinase is a component of glucose transporter (GLUT 4)-containing vesicles. The Journal of Biological Chemistry. 266: 13278-83. PMID 1649187  1
1990 Kasanicki MA, Pilch PF. Regulation of glucose-transporter function Diabetes Care. 13: 219-227. PMID 2407477  1
1990 Pilch PF. Editorial: Glucose transporters: What's in a name? Endocrinology. 126: 3-5. PMID 2403520  1
1990 Treadway JL, Morrison BD, Wemmie JA, Frias I, O'Hare T, Pilch PF, Pessin JE. The endogenous functional turkey erythrocyte and rat liver insulin receptor is an α2β2 heterotetrameric complex Biochemical Journal. 271: 99-105. PMID 2222423  1
1990 Strout HV, Vicario PP, Biswas C, Saperstein R, Brady EJ, Pilch PF, Berger J. Vanadate treatment of streptozotocin diabetic rats restores expression of the insulin-responsive glucose transporter in skeletal muscle Endocrinology. 126: 2728-2732. PMID 2184022  1
1990 O'Hare T, Pilch PF. Intrinsic kinase activity of the insulin receptor International Journal of Biochemistry. 22: 315-324. PMID 2159922 DOI: 10.1016/0020-711X(90)90132-M  1
1989 Waugh SM, DiBella EE, Pilch PF. Isolation of a proteolytically derived domain of the insulin receptor containing the major site of cross-linking/binding Biochemistry. 28: 3448-3455. PMID 2742847  1
1989 Berger J, Biswas C, Vicario PP, Strout HV, Saperstein R, Pilch PF. Decreased expression of the insulin-responsive glucose transporter in diabetes and fasting Nature. 340: 70-72. PMID 2739728  1
1989 Vilaró S, Palacín M, Pilch PF, Testar X, Zorzano A. Expression of an insulin-regulatable glucose carrier in muscle and fat endothelial cells Nature. 342: 798-800. PMID 2689883  1
1989 Waugh SM, Pilch PF. Insulin binding changes the interface region between α subunits of the insulin receptor Biochemistry. 28: 2722-2727. PMID 2659079  1
1989 Fukumoto H, Kayano T, Buse JB, Edwards Y, Pilch PF, Bell GI, Seino S. Cloning and characterization of the major insulin-responsive glucose transporter expressed in human skeletal muscle and other insulin-responsive tissues Journal of Biological Chemistry. 264: 7776-7779. PMID 2656669  1
1989 Zorzano A, Wilkinson W, Kotliar N, Thoidis G, Wadzinkski BE, Ruoho AE, Pilch PF. Insulin-regulated glucose uptake in rat adipocytes is mediated by two transporter isoforms present in at least two vesicle populations Journal of Biological Chemistry. 264: 12358-12363. PMID 2545707  1
1989 O'Hare T, Pilch PF. Intrinsic kinase activity of the insulin receptor. The intact (α2β2) insulin receptor from rat liver contains a kinase domain with greater intrinsic activity than the intact insulin receptor from human placenta Journal of Biological Chemistry. 264: 602-610. PMID 2535848  1
1989 Del Vecchio RL, Pilch PF. Insulin stimulates the tyrosine phosphorylation of a 165 kDa protein that is associated with microsomal membranes of rat adipocytes. Biochimica Et Biophysica Acta. 986: 41-6. PMID 2479417 DOI: 10.1016/0005-2736(89)90270-8  1
1989 Goldstein RH, Poliks CF, Pilch PF, Smith BD, Fine A. Stimulation of collagen formation by insulin and insulin-like growth factor I in cultures of human lung fibroblasts Endocrinology. 124: 964-970. PMID 2463909  1
1988 James DE, Brown R, Navarro J, Pilch PF. Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein Nature. 333: 183-185. PMID 3285221  1
1988 Tapson VF, Boni-Schnetzler M, Pilch PF, Center DM, Berman JS. Structural and functional characterization of the human T lymphocyte receptor for insulin-like growth factor I in vitro Journal of Clinical Investigation. 82: 950-957. PMID 3262126  1
1988 James DE, Pilch PF. Fractionation of endocytic vesicles and glucose-transporter-containing vesicles in rat adipocytes Biochemical Journal. 256: 725-732. PMID 3066353  1
1988 O'Hare T, Pilch PF. Separation and characterization of three insulin receptor species that differ in subunit composition Biochemistry. 27: 5693-5700. PMID 3052583  1
1988 Zorzano A, James DE, Ruderman NB, Pilch PF. Insulin-like growth factor I binding and receptor kinase in red and white muscle Febs Letters. 234: 257-262. PMID 2968920 DOI: 10.1016/0014-5793(88)80093-0  1
1988 Roome J, O'Hare T, Pilch PF, Brautigan DL. Protein phosphotyrosine phosphatase purified from the particulate fraction of human placenta dephosphorylates insulin and growth-factor receptors Biochemical Journal. 256: 493-500. PMID 2851993  1
1988 Boni-Schnetzler M, Kaligian A, DelVecchio R, Pilch PF. Ligand-dependent intersubunit association within the insulin receptor complex activates its intrinsic kinase activity Journal of Biological Chemistry. 263: 6822-6828. PMID 2834392  1
1988 Aiello LP, Shia MA, Robinson GS, Pilch PF, Farmer SR. Characterization and hepatic expression of rat α1-inhibitor III mRNA Journal of Biological Chemistry. 263: 4013-4022. PMID 2450089  1
1987 Boni-Schnetzler M, Scott W, Waugh S, DiBella E, Pilch PF. The insulin receptor. Structural basis for high affinity ligand binding Journal of Biological Chemistry. 262: 8395-8401. PMID 3597378  1
1987 Böni-Schnetzler M, Pilch PF. Mechanism of epidermal growth factor receptor autophosphorylation and high-affinity binding Proceedings of the National Academy of Sciences of the United States of America. 84: 7832-7836. PMID 3500470  1
1987 Cousin JL, Samson M, Pilch PF, Fehlmann M. Internalization of insulin receptors and HLA antigens in human hepatoma cells Biochemical Journal. 242: 403-410. PMID 3036089  1
1987 James DE, Ledermans L, Pilch PF. Purification of insulin-dependent exocytic vesicles containing the glucose transporter Journal of Biological Chemistry. 262: 11817-11824. PMID 2957373  1
1986 Aiello LP, Wessling-Resnick M, Pilch PF. Dipeptide metalloendoprotease substrates are glucose transport inhibitors and membrane structure perturbants Biochemistry. 25: 3944-3950. PMID 3527260  1
1986 Böni-Schnetzler M, Rubin JB, Pilch PF. Structural requirements for the transmembrane activation of the insulin receptor kinase. The Journal of Biological Chemistry. 261: 15281-7. PMID 3021769  1
1986 James DE, Zorzano A, Boni-Schnetzler M, Nemenoff RA, Powers A, Pilch PF, Ruderman NB. Intrinsic differences of insulin receptor kinase activity in red and white muscle Journal of Biological Chemistry. 261: 14939-14944. PMID 3021758  1
1986 Pilch PF, O'Hare T, Rubin J, Boni-Schnetzler M. The ligand binding subunit of the insulin-like growth factor 1 receptor has properties of a peripheral membrane protein Biochemical and Biophysical Research Communications. 136: 45-50. PMID 3010976 DOI: 10.1016/0006-291X(86)90874-0  1
1985 Aiello LP, Pilch PF, Farmer SR. Partial sequence and hepatic expression of rat insulin receptor mRNA Federation Proceedings. 44.  1
1985 Shia MA, Aiello LP, Pilch PF, Farmer SR. Molecular cloning of the rat insulin receptor Federation Proceedings. 44.  1
1984 Wessling M, Pilch PF. Characterization and solubilization of the cytochalasin B binding component from human placental microsomes Bba - Biomembranes. 777: 123-132. PMID 6541505 DOI: 10.1016/0005-2736(84)90504-2  1
1984 Campbell C, Squicciarini J, Shia M, Pilch PF, Fine RE. Identification of a protein kinase as an intrinsic component of rat liver coated vesicles Biochemistry. 23: 4420-4426. PMID 6148963  1
1984 Wessling M, Pilch PF. Cytochalasin B binding component from human placental microsomes: Characterization and solubilization Federation Proceedings. 43.  1
1983 Axelrod JD, Pilch PF. Unique cytochalasin B binding characteristics of the hepatic glucose carrier. Biochemistry. 22: 2222-7. PMID 6683102  1
1983 Shia MA, Rubin JB, Pilch PF. The insulin receptor protein kinase. Physicochemical requirements for activity. The Journal of Biological Chemistry. 258: 14450-5. PMID 6557114  1
1983 Shia MA, Pilch PF. The β subunit of the insulin receptor is an insulin-activated protein kinase Biochemistry. 22: 717-721. PMID 6340724  1
1983 Rubin JB, Shia MA, Pilch PF. Stimulation of tyrosine-Specific phosphorylation in vitro by insulin-Like growth factor I Nature. 305: 438-440. PMID 6312321 DOI: 10.1038/305438a0  1
1983 Pilch PF, Shia MA, Benson RJ, Fine RE. Coated vesicles participate in the receptor-mediated endocytosis of insulin. The Journal of Cell Biology. 96: 133-8. PMID 6131074  1
1982 Pilch PF. Modification of the insulin receptor by diethyl pyrocarbonate: Effect on insulin binding and action Biochemistry. 21: 5638-5644. PMID 6756473  1
1982 Pilch PF. An insulin receptor histidine residue is required for hormone binding Diabetes. 31.  1
1981 Massague J, Pilch PF, Czech MP. A unique proteolytic cleavage site on the β subunit of the insulin receptor Journal of Biological Chemistry. 256: 3182-3190. PMID 7009609  1
1981 Carter-Su C, Pilch PF, Czech MP. Chromatographic resolution of insulin receptor from insulin-sensitive D-glucose transporter of adipocyte plasma membranes Biochemistry. 20: 216-221. PMID 7008832  1
1981 Pilch PF, Axelrod JD, Colello J, Czech MP. Unimpaired signal transduction by the adipocyte insulin receptor following its partial proteolytic fragmentation. The Journal of Biological Chemistry. 256: 1570-5. PMID 7007367  1
1981 Johnson GL, MacAndrew VI, Pilch PF. Identification of the glucagon receptor in rat liver membranes by photoaffinity crosslinking Proceedings of the National Academy of Sciences of the United States of America. 78: 875-878. PMID 6262779  1
1981 Czech MP, Massague J, Pilch PF. The insulin receptor: structural features Trends in Biochemical Sciences. 6: 222-225. DOI: 10.1016/0968-0004(81)90081-5  1
1980 Pilch PF, Czech MP. Hexose transport in adipocytes: Stimulation by insulin in the absence of intact receptor Annals of the New York Academy of Sciences. 356. PMID 7011151  1
1980 Czech MP, Massague J, Pilch PF, Carter-Su C. Structural features of the insulin effector system: Relation to hexose transport activation Annals of the New York Academy of Sciences. 282-291. PMID 7011146  1
1980 Pilch PF, Czech MP. Hormone binding alters the conformation of the insulin receptor Science. 210: 1152-1153. PMID 7003712  1
1980 Pilch PF, Thompson PA, Czech MP. Coordinate modulation of D-glucose transport activity and bilayer fluidity in plasma membranes derived from control and insulin-treated adipocytes Proceedings of the National Academy of Sciences of the United States of America. 77: 915-918. PMID 6987672  1
1980 Heinrich J, Pilch PF, Czech MP. Purification of the adipocyte insulin receptor by immunoaffinity chromatography Journal of Biological Chemistry. 255: 1732-1737. PMID 6986379  1
1980 Pilch PF, Czech MP. The subunit structure of the high affinity insulin receptor. Evidence for a disulfide-linked receptor complex in fat cell and liver plasma membranes Journal of Biological Chemistry. 255: 1722-1731. PMID 6986378  1
1980 Massague J, Pilch PF, Czech MP. Electrophoretic resolution of three major insulin receptor structures with unique subunit stoichiometries Proceedings of the National Academy of Sciences of the United States of America. 77: 7137-7141. PMID 6938960  1
1980 Pillion DJ, Carter-Su CA, Pilch PF, Czech MP. Isolation of adipocyte plasma membrane antigens by immunoaffinity chromatography. Insulinomimetic antibodies do not bind directly to the insulin receptor or the glucose transport system Journal of Biological Chemistry. 255: 9168-9176. PMID 6773960  1
1980 Czech MP, Malbon CC, Kerman K, Gitomer W, Pilch PF. Effect of thyroid status on insulin action in rat adipocytes and skeletal muscle Journal of Clinical Investigation. 66: 574-582. PMID 6249852  1
1980 Pilch PF, Czech MP. Peptide mapping of the adipocyte insulin receptor Journal of Supramolecular and Cellular Biochemistry. 12.  1
1980 Massague J, Pilch PF, Czech MP. Insulin receptor structure: Multiple disulfide-linked forms in adipocyte plasma membrane Journal of Supramolecular and Cellular Biochemistry. 12.  1
1980 Czech MP, Massague J, Pilch PF. Transmembrane signaling mechanisms in the action of insulin European Journal of Cell Biology. 22.  1
1980 Carter-Su C, Pilch PF, Czech MP. Chromatographic resolution of the adipocyte high affinity insulin receptor from the insulin sensitive D-glucose transporter Journal of Supramolecular and Cellular Biochemistry. 12.  1
1979 Pilch PF, Czech MP. Interaction of cross linking agents with the insulin effector system of isolated fat cells. Covalent linkage of 125I insulin to a plasma membrane receptor protein of 140,000 daltons Journal of Biological Chemistry. 254: 3375-3381. PMID 429356  1
1979 Pilch PF, Czech MP. Covalent cross-linking of 125I-insulin to a plasma membrane receptor protein of rat adipocytes and hepatocytes Federation Proceedings. 38.  1
1978 Pilch PF, Czech MP. Selective inhibition of insulin action by chemical cross-linking in the rat adipocyte Federation Proceedings. 37.  1
1977 Pilch PF, Somerville RL. Periodate oxidation of vicinal hydroxyls: Applications to student experiments Journal of Chemical Education. 54: 449.  1
1976 Pilch PF, Somerville RL. Fluorine-containing analogues of intermediates in the shikimate pathway Biochemistry. 15: 5315-5320. PMID 11811  1
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