| Year |
Citation |
Score |
| 2020 |
Metzger JM, Lopez MS, Schmidt JK, Murphy ME, Vemuganti R, Emborg ME. Effects of Cardiac Sympathetic Neurodegeneration and PPAR Activation on Rhesus Macaque Whole Blood miRNA and mRNA Expression Profiles. Biomed Research International. 2020: 9426204. PMID 32462037 DOI: 10.1155/2020/9426204 |
0.325 |
|
| 2020 |
Vermilyea SC, Babinski A, Tran N, To S, Guthrie S, Kluss JH, Schmidt JK, Wiepz GJ, Meyer MG, Murphy ME, Cookson MR, Emborg ME, Golos TG. In Vitro CRISPR/Cas9-Directed Gene Editing to Model LRRK2 G2019S Parkinson's Disease in Common Marmosets. Scientific Reports. 10: 3447. PMID 32103062 DOI: 10.1038/S41598-020-60273-2 |
0.362 |
|
| 2020 |
Metzger JM, Matsoff HN, Zinnen AD, Fleddermann RA, Bondarenko V, Simmons HA, Mejia A, Moore CF, Emborg ME. Post mortem evaluation of inflammation, oxidative stress, and PPARγ activation in a nonhuman primate model of cardiac sympathetic neurodegeneration. Plos One. 15: e0226999. PMID 31910209 DOI: 10.1371/Journal.Pone.0226999 |
0.402 |
|
| 2019 |
Resnikoff H, Metzger JM, Lopez M, Bondarenko V, Mejia A, Simmons HA, Emborg ME. Colonic inflammation affects myenteric alpha-synuclein in nonhuman primates. Journal of Inflammation Research. 12: 113-126. PMID 31123415 DOI: 10.2147/Jir.S196552 |
0.348 |
|
| 2019 |
Metzger JM, Emborg ME. Autonomic dysfunction in Parkinson disease and animal models. Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society. PMID 30604165 DOI: 10.1007/S10286-018-00584-7 |
0.385 |
|
| 2018 |
Sison SL, Vermilyea SC, Emborg ME, Ebert AD. Using Patient-Derived Induced Pluripotent Stem Cells to Identify Parkinson's Disease-Relevant Phenotypes. Current Neurology and Neuroscience Reports. 18: 84. PMID 30284665 DOI: 10.1007/S11910-018-0893-8 |
0.439 |
|
| 2018 |
Vermilyea SC, Emborg ME. In Vitro Modeling of Leucine-Rich Repeat Kinase 2 G2019S-Mediated Parkinson's Disease Pathology. Stem Cells and Development. 27: 960-967. PMID 29402177 DOI: 10.1089/Scd.2017.0286 |
0.33 |
|
| 2017 |
Vermilyea SC, Emborg ME. The role of nonhuman primate models in the development of cell-based therapies for Parkinson's disease. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 28326445 DOI: 10.1007/s00702-017-1708-9 |
0.336 |
|
| 2016 |
Shultz JM, Resnikoff H, Bondarenko V, Joers V, Mejia A, Simmons H, Emborg ME. Neurotoxin-Induced Catecholaminergic Loss in the Colonic Myenteric Plexus of Rhesus Monkeys. Journal of Alzheimer's Disease & Parkinsonism. 6. PMID 28090391 DOI: 10.4172/2161-0460.1000279 |
0.711 |
|
| 2015 |
Simon DK, Simuni T, Elm J, Clark-Matott J, Graebner AK, Baker L, Dunlop SR, Emborg M, Kamp C, Morgan JC, Ross GW, Sharma S, Ravina B. Peripheral Biomarkers of Parkinson's Disease Progression and Pioglitazone Effects. Journal of Parkinson's Disease. PMID 26444095 DOI: 10.3233/Jpd-150666 |
0.391 |
|
| 2015 |
Vermilyea SC, Emborg ME. α-Synuclein and nonhuman primate models of Parkinson's disease. Journal of Neuroscience Methods. 255: 38-51. PMID 26247888 DOI: 10.1016/J.Jneumeth.2015.07.025 |
0.355 |
|
| 2014 |
Joers V, Vermilyea S, Dilley K, Emborg ME. Systemic administration of 6-OHDA to rhesus monkeys upregulates HLA-DR expression in brain microvasculature. Journal of Inflammation Research. 7: 139-49. PMID 25258551 DOI: 10.2147/Jir.S67285 |
0.748 |
|
| 2014 |
Joers V, Dilley K, Rahman S, Jones C, Shultz J, Simmons H, Emborg ME. Cardiac sympathetic denervation in 6-OHDA-treated nonhuman primates. Plos One. 9: e104850. PMID 25133405 DOI: 10.1371/Journal.Pone.0104850 |
0.731 |
|
| 2014 |
Emborg ME, Hurley SA, Joers V, Tromp do PM, Swanson CR, Ohshima-Hosoyama S, Bondarenko V, Cummisford K, Sonnemans M, Hermening S, Blits B, Alexander AL. Titer and product affect the distribution of gene expression after intraputaminal convection-enhanced delivery. Stereotactic and Functional Neurosurgery. 92: 182-94. PMID 24943657 DOI: 10.1159/000360584 |
0.742 |
|
| 2014 |
Joers V, Emborg ME. Modeling and imaging cardiac sympathetic neurodegeneration in Parkinson's disease. American Journal of Nuclear Medicine and Molecular Imaging. 4: 125-59. PMID 24753981 |
0.715 |
|
| 2014 |
Swanson C, Emborg M. Expression of peroxisome proliferator-activated receptor-gamma in the substantia nigra of hemiparkinsonian nonhuman primates. Neurological Research. 36: 634-46. PMID 24620964 DOI: 10.1179/1743132813Y.0000000305 |
0.646 |
|
| 2013 |
Swanson CR, Du E, Johnson DA, Johnson JA, Emborg ME. Neuroprotective Properties of a Novel Non-Thiazoledinedione Partial PPAR- γ Agonist against MPTP. Ppar Research. 2013: 582809. PMID 24223584 DOI: 10.1155/2013/582809 |
0.703 |
|
| 2013 |
Emborg ME, Zhang Z, Joers V, Brunner K, Bondarenko V, Ohshima S, Zhang SC. Intracerebral transplantation of differentiated human embryonic stem cells to hemiparkinsonian monkeys. Cell Transplantation. 22: 831-8. PMID 23594934 DOI: 10.3727/096368912X647144 |
0.752 |
|
| 2013 |
Emborg ME, Liu Y, Xi J, Zhang X, Yin Y, Lu J, Joers V, Swanson C, Holden JE, Zhang SC. Induced pluripotent stem cell-derived neural cells survive and mature in the nonhuman primate brain. Cell Reports. 3: 646-50. PMID 23499447 DOI: 10.1016/J.Celrep.2013.02.016 |
0.761 |
|
| 2013 |
Cibelli J, Emborg ME, Prockop DJ, Roberts M, Schatten G, Rao M, Harding J, Mirochnitchenko O. Strategies for improving animal models for regenerative medicine. Cell Stem Cell. 12: 271-4. PMID 23472868 DOI: 10.1016/J.Stem.2013.01.004 |
0.337 |
|
| 2013 |
Brady ML, Raghavan R, Alexander A, Kubota K, Sillay K, Emborg ME. Pathways of infusate loss during convection-enhanced delivery into the putamen nucleus. Stereotactic and Functional Neurosurgery. 91: 69-78. PMID 23344643 DOI: 10.1159/000342492 |
0.346 |
|
| 2012 |
Ohshima-Hosoyama S, Simmons HA, Goecks N, Joers V, Swanson CR, Bondarenko V, Velotta R, Brunner K, Wood LD, Hruban RH, Emborg ME. A monoclonal antibody-GDNF fusion protein is not neuroprotective and is associated with proliferative pancreatic lesions in parkinsonian monkeys. Plos One. 7: e39036. PMID 22745701 DOI: 10.1371/Journal.Pone.0039036 |
0.783 |
|
| 2012 |
Xi J, Liu Y, Liu H, Chen H, Emborg ME, Zhang SC. Specification of midbrain dopamine neurons from primate pluripotent stem cells. Stem Cells (Dayton, Ohio). 30: 1655-63. PMID 22696177 DOI: 10.1002/Stem.1152 |
0.386 |
|
| 2012 |
Joers V, Seneczko K, Goecks NC, Kamp TJ, Hacker TA, Brunner KG, Engle JW, Barnhart TE, Nickles RJ, Holden JE, Emborg ME. Nonuniform cardiac denervation observed by 11C-meta-hydroxyephedrine PET in 6-OHDA-treated monkeys. Plos One. 7: e35371. PMID 22539969 DOI: 10.1371/Journal.Pone.0035371 |
0.733 |
|
| 2011 |
Swanson CR, Joers V, Bondarenko V, Brunner K, Simmons HA, Ziegler TE, Kemnitz JW, Johnson JA, Emborg ME. The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys. Journal of Neuroinflammation. 8: 91. PMID 21819568 DOI: 10.1186/1742-2094-8-91 |
0.774 |
|
| 2010 |
Emborg ME, Joers V, Fisher R, Brunner K, Carter V, Ross C, Raghavan R, Brady M, Raschke J, Kubota K, Alexander A. Intraoperative intracerebral MRI-guided navigation for accurate targeting in nonhuman primates. Cell Transplantation. 19: 1587-97. PMID 20587170 DOI: 10.3727/096368910X514323 |
0.693 |
|
| 2010 |
Hegge JO, Wooddell CI, Zhang G, Hagstrom JE, Braun S, Huss T, Sebestyén MG, Emborg ME, Wolff JA. Evaluation of hydrodynamic limb vein injections in nonhuman primates. Human Gene Therapy. 21: 829-42. PMID 20163248 DOI: 10.1089/Hum.2009.172 |
0.308 |
|
| 2009 |
Joers VL, Emborg ME. Preclinical assessment of stem cell therapies for neurological diseases. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 51: 24-41. PMID 20075496 DOI: 10.1093/Ilar.51.1.24 |
0.736 |
|
| 2009 |
Kimmelman J, London AJ, Ravina B, Ramsay T, Bernstein M, Fine A, Stahnisch FW, Emborg ME. Launching invasive, first-in-human trials against Parkinson's disease: ethical considerations. Movement Disorders : Official Journal of the Movement Disorder Society. 24: 1893-901. PMID 19672990 DOI: 10.1002/Mds.22712 |
0.316 |
|
| 2009 |
Emborg ME, Moirano J, Raschke J, Bondarenko V, Zufferey R, Peng S, Ebert AD, Joers V, Roitberg B, Holden JE, Koprich J, Lipton J, Kordower JH, Aebischer P. Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF. Neurobiology of Disease. 36: 303-11. PMID 19660547 DOI: 10.1016/J.Nbd.2009.07.022 |
0.739 |
|
| 2009 |
Fitzpatrick KM, Raschke J, Emborg ME. Cell-based therapies for Parkinson's disease: past, present, and future. Antioxidants & Redox Signaling. 11: 2189-208. PMID 19485712 DOI: 10.1089/Ars.2009.2654 |
0.427 |
|
| 2009 |
Swanson CR, Sesso SL, Emborg ME. Can we prevent parkinson's disease? Frontiers in Bioscience (Landmark Edition). 14: 1642-60. PMID 19273153 DOI: 10.2741/3331 |
0.685 |
|
| 2008 |
Emborg ME, Ebert AD, Moirano J, Peng S, Suzuki M, Capowski E, Joers V, Roitberg BZ, Aebischer P, Svendsen CN. GDNF-secreting human neural progenitor cells increase tyrosine hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeys. Cell Transplantation. 17: 383-95. PMID 18522241 DOI: 10.3727/096368908784423300 |
0.751 |
|
| 2008 |
Capitanio JP, Emborg ME. Contributions of non-human primates to neuroscience research. Lancet. 371: 1126-35. PMID 18374844 DOI: 10.1016/S0140-6736(08)60489-4 |
0.324 |
|
| 2007 |
Emborg ME. Nonhuman primate models of Parkinson's disease. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 48: 339-55. PMID 17712221 DOI: 10.1093/Ilar.48.4.339 |
0.413 |
|
| 2007 |
Stephenson DT, Childs MA, Li Q, Carvajal-Gonzalez S, Opsahl A, Tengowski M, Meglasson MD, Merchant K, Emborg ME. Differential loss of presynaptic dopaminergic markers in Parkinsonian monkeys. Cell Transplantation. 16: 229-44. PMID 17503735 |
0.306 |
|
| 2007 |
Emborg ME, Carbon M, Holden JE, During MJ, Ma Y, Tang C, Moirano J, Fitzsimons H, Roitberg BZ, Tuccar E, Roberts A, Kaplitt MG, Eidelberg D. Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 501-9. PMID 16835631 DOI: 10.1038/Sj.Jcbfm.9600364 |
0.388 |
|
| 2006 |
Emborg ME, Roitberg BZ, Moirano J, Zufferey R, Ebert AD, Joers V, Holden J, Converse AK, Koprich JB, Kordower JH, Aebischer P. Lentiviral Delivery of Glial Cell Line-derived Neurotrophic Factor in Aged 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated Rhesus Monkeys 883. Neurosurgery. 59: 481-482. PMID 28180727 DOI: 10.1227/00006123-200608000-00121 |
0.71 |
|
| 2006 |
Roitberg BZ, Mangubat E, Chen EY, Sugaya K, Thulborn KR, Kordower JH, Pawar A, Konecny T, Emborg ME. Survival and early differentiation of human neural stem cells transplanted in a nonhuman primate model of stroke. Journal of Neurosurgery. 105: 96-102. PMID 16871883 DOI: 10.3171/Jns.2006.105.1.96 |
0.33 |
|
| 2006 |
Emborg ME, Moirano J, Schafernak KT, Moirano M, Evans M, Konecny T, Roitberg B, Ambarish P, Mangubat E, Ma Y, Eidelberg D, Holden J, Kordower JH, Leestma JE. Basal ganglia lesions after MPTP administration in rhesus monkeys. Neurobiology of Disease. 23: 281-9. PMID 16766201 DOI: 10.1016/J.Nbd.2006.03.010 |
0.375 |
|
| 2006 |
Moirano J, Zufferey R, Peng S, Ebert A, Joers V, Breburda E, Roitberg B, Holden J, Koprich J, Lipton J, Kordower J, Aebischer P, Emborg M. Lentiviral delivery of GDNF in aged MPTP-treated rhesus monkeys: Correlations between functional measures Experimental Neurology. 198: 581. DOI: 10.1016/J.Expneurol.2006.02.073 |
0.703 |
|
| 2006 |
Emborg M, Peng S, Moirano J, Ebert A, Suzuki M, Capowski B, Joers V, Roitberg B, Aebischer P, Svendsen C. Survival of human neural stem cells (HNSCs) expressing GDNF in mptp-treated rhesus monkeys Experimental Neurology. 198: 567. DOI: 10.1016/J.Expneurol.2006.02.039 |
0.724 |
|
| 2006 |
Moirano J, Emborg ME. Nonhuman Primate Models for Testing Gene Therapy for Neurodegenerative Disorders Gene Therapy of the Central Nervous System: From Bench to Bedside. 109-119. DOI: 10.1016/B978-012397632-1/50010-1 |
0.325 |
|
| 2005 |
Stephenson DT, Meglasson MD, Connell MA, Childs MA, Hajos-Korcsok E, Emborg ME. The effects of a selective dopamine D2 receptor agonist on behavioral and pathological outcome in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 314: 1257-66. PMID 15980058 DOI: 10.1124/Jpet.105.087379 |
0.361 |
|
| 2005 |
Stephenson DT, Li Q, Simmons C, Connell MA, Meglasson MD, Merchant K, Emborg ME. Expression of GAD65 and GAD67 immunoreactivity in MPTP-treated monkeys with or without L-DOPA administration. Neurobiology of Disease. 20: 347-59. PMID 15882945 DOI: 10.1016/J.Nbd.2005.03.016 |
0.385 |
|
| 2004 |
Emborg ME. Evaluation of animal models of Parkinson's disease for neuroprotective strategies. Journal of Neuroscience Methods. 139: 121-43. PMID 15488225 DOI: 10.1016/J.Jneumeth.2004.08.004 |
0.444 |
|
| 2004 |
Roitberg B, Urbaniak K, Emborg M. Cell transplantation for Parkinson's disease. Neurological Research. 26: 355-62. PMID 15198860 DOI: 10.1179/016164104225017604 |
0.434 |
|
| 2004 |
Barcia C, Emborg ME, Hirsch EC, Herrero MT. Blood vessels and parkinsonism. Frontiers in Bioscience : a Journal and Virtual Library. 9: 277-82. PMID 14766365 DOI: 10.2741/1145 |
0.42 |
|
| 2003 |
Oiwa Y, Eberling JL, Nagy D, Pivirotto P, Emborg ME, Bankiewicz KS. Overlesioned hemiparkinsonian non human primate model: correlation between clinical, neurochemical and histochemical changes. Frontiers in Bioscience : a Journal and Virtual Library. 8: a155-66. PMID 12957824 DOI: 10.2741/1104 |
0.437 |
|
| 2003 |
Kus L, Borys E, Ping Chu Y, Ferguson SM, Blakely RD, Emborg ME, Kordower JH, Levey AI, Mufson EJ. Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system. The Journal of Comparative Neurology. 463: 341-57. PMID 12820166 DOI: 10.1002/Cne.10759 |
0.307 |
|
| 2003 |
Emborg ME, Tetrud JW, Moirano J, McLaughlin WW, Bankiewicz KS. Rest tremor in rhesus monkeys with MPTP-induced parkinsonism. Frontiers in Bioscience : a Journal and Virtual Library. 8: a148-54. PMID 12700090 DOI: 10.2741/1088 |
0.439 |
|
| 2003 |
Roitberg B, Khan N, Tuccar E, Kompoliti K, Chu Y, Alperin N, Kordower JH, Emborg ME. Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study. Neurological Research. 25: 68-78. PMID 12564129 DOI: 10.1179/016164103101200950 |
0.336 |
|
| 2002 |
Eberling JL, Pivirotto P, Bringas J, Steiner JP, Kordower JH, Chu Y, Emborg ME, Bankiewicz KS. The immunophilin ligand GPI-1046 does not have neuroregenerative effects in MPTP-treated monkeys. Experimental Neurology. 178: 236-42. PMID 12504882 DOI: 10.1006/Exnr.2002.8023 |
0.404 |
|
| 2002 |
Palfi S, Leventhal L, Chu Y, Ma SY, Emborg M, Bakay R, Déglon N, Hantraye P, Aebischer P, Kordower JH. Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4942-54. PMID 12077191 DOI: 10.1523/Jneurosci.22-12-04942.2002 |
0.383 |
|
| 2002 |
Roitberg BZ, Emborg ME, Sramek JG, Palfi S, Kordower JH. Behavioral and morphological comparison of two nonhuman primate models of Huntington's disease. Neurosurgery. 50: 137-45; discussion 1. PMID 11844244 DOI: 10.1097/00006123-200201000-00022 |
0.357 |
|
| 2001 |
Emborg ME, Shin P, Roitberg B, Sramek JG, Chu Y, Stebbins GT, Hamilton JS, Suzdak PD, Steiner JP, Kordower JH. Systemic administration of the immunophilin ligand GPI 1046 in MPTP-treated monkeys Experimental Neurology. 168: 171-182. PMID 11170732 DOI: 10.1006/Exnr.2000.7592 |
0.425 |
|
| 2001 |
Emborg ME, Deglon N, Leventhal L, Aebischer P, Kordower JH. Viral vector-mediated gene therapy for Parkinson's disease Clinical Neuroscience Research. 1: 496-506. DOI: 10.1016/S1566-2772(01)00027-5 |
0.422 |
|
| 2000 |
Bankiewicz KS, Bringas J, Pivirotto P, Kutzscher E, Nagy D, Emborg ME. Technique for bilateral intracranial implantation of cells in monkeys using an automated delivery system. Cell Transplantation. 9: 595-607. PMID 11144957 DOI: 10.1177/096368970000900505 |
0.324 |
|
| 2000 |
Kordower JH, Emborg ME, Bloch J, Ma SY, Chu Y, Leventhal L, McBride J, Chen EY, Palfi S, Roitberg BZ, Brown WD, Holden JE, Pyzalski R, Taylor MD, Carvey P, et al. Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science (New York, N.Y.). 290: 767-73. PMID 11052933 DOI: 10.1126/Science.290.5492.767 |
0.5 |
|
| 1999 |
Kordower JH, Bloch J, Ma SY, Chu Y, Palfi S, Roitberg BZ, Emborg M, Hantraye P, Déglon N, Aebischer P. Lentiviral gene transfer to the nonhuman primate brain. Experimental Neurology. 160: 1-16. PMID 10630186 DOI: 10.1006/Exnr.1999.7178 |
0.394 |
|
| 1998 |
Emborg ME, Ma SY, Mufson EJ, Levey AI, Taylor MD, Brown WD, Holden JE, Kordower JH. Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys. The Journal of Comparative Neurology. 401: 253-65. PMID 9822152 DOI: 10.1002/(Sici)1096-9861(19981116)401:2<253::Aid-Cne7>3.0.Co;2-X |
0.359 |
|
| 1998 |
Bankiewicz KS, Bringas JR, McLaughlin W, Pivirotto P, Hundal R, Yang B, Emborg ME, Nagy D. Application of gene therapy for Parkinson's disease: nonhuman primate experience. Advances in Pharmacology (San Diego, Calif.). 42: 801-6. PMID 9328019 DOI: 10.1016/S1054-3589(08)60868-6 |
0.399 |
|
| 1997 |
Jordan S, Eberling JL, Bankiewicz KS, Rosenberg D, Coxson PG, VanBrocklin HF, O'Neil JP, Emborg ME, Jagust WJ. 6-[18F]fluoro-L-m-tyrosine: metabolism, positron emission tomography kinetics, and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine lesions in primates. Brain Research. 750: 264-76. PMID 9098552 DOI: 10.1016/S0006-8993(96)01366-2 |
0.305 |
|
| 1994 |
Emborg ME, Colombo JA. Long-term MPTP-treated monkeys are resistant to GM1 systemic therapy. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 21: 75-82. PMID 8179773 DOI: 10.1007/Bf03160086 |
0.381 |
|
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