| Year |
Citation |
Score |
| 2022 |
Dogan M, Karhan E, Kozhaya L, Placek L, Chen X, Yigit M, Unutmaz D. Engineering Human MAIT Cells with Chimeric Antigen Receptors for Cancer Immunotherapy. Journal of Immunology (Baltimore, Md. : 1950). PMID 36165183 DOI: 10.4049/jimmunol.2100856 |
0.516 |
|
| 2022 |
Dey M, Kim MH, Nagamine MT, Karhan E, Kozhaya L, Dogan M, Unutmaz D, Ozbolat IT. Biofabrication of 3D Breast cancer models for dissecting the cytotoxic response of human T cells expressing engineered MAIT cell receptors. Biofabrication. PMID 36108605 DOI: 10.1088/1758-5090/ac925a |
0.389 |
|
| 2022 |
Zhang S, Cooper-Knock J, Weimer AK, Shi M, Kozhaya L, Unutmaz D, Harvey C, Julian TH, Furini S, Frullanti E, Fava F, Renieri A, Gao P, Shen X, Timpanaro IS, et al. Multiomic analysis reveals cell-type-specific molecular determinants of COVID-19 severity. Cell Systems. PMID 35690068 DOI: 10.1016/j.cels.2022.05.007 |
0.369 |
|
| 2022 |
Unutmaz D. CCR5: The Receptor That Unlocks the Door for HIV Entry into Cells. Journal of Immunology (Baltimore, Md. : 1950). 208: 2459-2460. PMID 35595303 DOI: 10.4049/jimmunol.2200108 |
0.373 |
|
| 2021 |
Tailor J, Foldi J, Generoso M, McCarty B, Alankar A, Kilberg M, Mwamzuka M, Marshed F, Ahmed A, Liu M, Borkowsky W, Unutmaz D, Khaitan A. Disease Progression in Children with Perinatal HIV Correlates with Increased PD-1+ CD8 T Cells that Coexpress Multiple Immune Checkpoints. The Journal of Infectious Diseases. PMID 33864071 DOI: 10.1093/infdis/jiab204 |
0.433 |
|
| 2020 |
Saka D, Gökalp M, Piyade B, Cevik NC, Arik Sever E, Unutmaz D, Ceyhan GO, Demir IE, Asimgil H. Mechanisms of T-Cell Exhaustion in Pancreatic Cancer. Cancers. 12. PMID 32823814 DOI: 10.3390/cancers12082274 |
0.49 |
|
| 2020 |
Kahlfuss S, Kaufmann U, Concepcion AR, Noyer L, Raphael D, Vaeth M, Yang J, Pancholi P, Maus M, Muller J, Kozhaya L, Khodadadi-Jamayran A, Sun Z, Shaw P, Unutmaz D, et al. STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells. Embo Molecular Medicine. e11592. PMID 32609955 DOI: 10.15252/Emmm.201911592 |
0.504 |
|
| 2020 |
Nasrallah R, Imianowski CJ, Bossini-Castillo L, Grant FM, Dogan M, Placek L, Kozhaya L, Kuo P, Sadiyah F, Whiteside SK, Mumbach MR, Glinos D, Vardaka P, Whyte CE, Lozano T, ... ... Unutmaz D, et al. A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by T cells. Nature. PMID 32499651 DOI: 10.1038/S41586-020-2296-7 |
0.498 |
|
| 2020 |
Liu J, Kozhaya L, Torres VJ, Unutmaz D, Lu M. Structure-based discovery of a small-molecule inhibitor of methicillin-resistant virulence. The Journal of Biological Chemistry. PMID 32179646 DOI: 10.1074/Jbc.Ra120.012697 |
0.342 |
|
| 2020 |
Keller MD, Ching KL, Liang FX, Dhabaria A, Tam K, Ueberheide BM, Unutmaz D, Torres VJ, Cadwell K. Decoy exosomes provide protection against bacterial toxins. Nature. PMID 32132711 DOI: 10.1038/S41586-020-2066-6 |
0.353 |
|
| 2019 |
Oh J, Unutmaz D. Immune cells for microbiota surveillance. Science (New York, N.Y.). 366: 419-420. PMID 31649181 DOI: 10.1126/science.aaz4014 |
0.311 |
|
| 2019 |
Sezen B, Koca S, Alan O, Renzullo S, Ozdemir F, Kozhaya L, Telli T, Karhan E, Ugurlu U, Gulluoglu B, Dane F, Yumuk F, Unutmaz D. Abstract P4-06-29: Prospective immune-profiling of locally advanced and metastatic breast cancer patients Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P4-06-29 |
0.319 |
|
| 2018 |
Shimada K, Porritt RA, Markman JL, O'Rourke JG, Wakita D, Noval Rivas M, Ogawa C, Kozhaya L, Martins GA, Unutmaz D, Baloh RH, Crother TR, Chen S, Arditi M. T Cell-Intrinsic Receptor Interacting Protein 2 Regulates Pathogenic T Helper 17 Cell Differentiation. Immunity. PMID 30366765 DOI: 10.1016/J.Immuni.2018.08.022 |
0.611 |
|
| 2018 |
McCarty B, Mwamzuka M, Marshed F, Generoso M, Alvarez P, Ilmet T, Kravietz A, Ahmed A, Borkowsky W, Unutmaz D, Khaitan A. Low Peripheral T Follicular Helper Cells in Perinatally HIV-Infected Children Correlate With Advancing HIV Disease. Frontiers in Immunology. 9: 1901. PMID 30197641 DOI: 10.3389/Fimmu.2018.01901 |
0.564 |
|
| 2018 |
Tastan C, Karhan E, Zhou W, Fleming E, Voigt AY, Yao X, Wang L, Horne M, Placek L, Kozhaya L, Oh J, Unutmaz D. Tuning of human MAIT cell activation by commensal bacteria species and MR1-dependent T-cell presentation. Mucosal Immunology. PMID 30115998 DOI: 10.1038/S41385-018-0072-X |
0.543 |
|
| 2018 |
Vermeersch E, Liénart S, Collignon A, Lucas S, Gallimore A, Gysemans C, Unutmaz D, Vanhoorelbeke K, De Meyer SF, Maes W, Deckmyn H. Deletion of GARP on mouse regulatory T cells is not sufficient to inhibit the growth of transplanted tumors. Cellular Immunology. PMID 30093071 DOI: 10.1016/J.Cellimm.2018.07.011 |
0.452 |
|
| 2018 |
Chen X, Kozhaya L, Tastan C, Placek L, Dogan M, Horne M, Abblett R, Karhan E, Vaeth M, Feske S, Unutmaz D. Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing. Journal of Immunology (Baltimore, Md. : 1950). PMID 30021769 DOI: 10.4049/Jimmunol.1701616 |
0.557 |
|
| 2017 |
Kwa M, Li X, Novik Y, Oratz R, Jhaveri K, Wu J, Gu P, Meyers M, Muggia F, Speyer J, Iwano A, Bonakdar M, Kozhaya L, Tavukcuoglu E, Budan B, ... ... Unutmaz D, et al. Serial immunological parameters in a phase II trial of exemestane and low-dose oral cyclophosphamide in advanced hormone receptor-positive breast cancer. Breast Cancer Research and Treatment. PMID 29124456 DOI: 10.1007/S10549-017-4570-4 |
0.337 |
|
| 2017 |
Foldi J, Kozhaya L, McCarty B, Mwamzuka M, Marshed F, Ilmet T, Kilberg M, Kravietz A, Ahmed A, Borkowsky W, Unutmaz D, Khaitan A. HIV-Infected Children Have Elevated Levels of PD-1+ Memory CD4 T Cells With Low Proliferative Capacity and High Inflammatory Cytokine Effector Functions. The Journal of Infectious Diseases. 216: 641-650. PMID 28934428 DOI: 10.1093/Infdis/Jix341 |
0.586 |
|
| 2016 |
Limgala RP, Ioanou C, Plassmeyer M, Ryherd M, Kozhaya L, Austin L, Abidoglu C, Unutmaz D, Alpan O, Goker-Alpan O. Time of Initiating Enzyme Replacement Therapy Affects Immune Abnormalities and Disease Severity in Patients with Gaucher Disease. Plos One. 11: e0168135. PMID 27942037 DOI: 10.1371/Journal.Pone.0168135 |
0.479 |
|
| 2016 |
Khaitan A, Kilberg M, Kravietz A, Ilmet T, Tastan C, Mwamzuka M, Marshed F, Liu M, Ahmed A, Borkowsky W, Unutmaz D. HIV-Infected Children Have Lower Frequencies of CD8+ Mucosal-Associated Invariant T (MAIT) Cells that Correlate with Innate, Th17 and Th22 Cell Subsets. Plos One. 11: e0161786. PMID 27560150 DOI: 10.1371/Journal.Pone.0161786 |
0.613 |
|
| 2016 |
Vaeth M, Eckstein M, Shaw PJ, Kozhaya L, Yang J, Berberich-Siebelt F, Clancy R, Unutmaz D, Feske S. Store-Operated Ca(2+) Entry in Follicular T Cells Controls Humoral Immune Responses and Autoimmunity. Immunity. PMID 27261277 DOI: 10.1016/J.Immuni.2016.04.013 |
0.551 |
|
| 2016 |
Khaitan A, Kravietz A, Mwamzuka M, Marshed F, Ilmet T, Said S, Ahmed A, Borkowsky W, Unutmaz D. FOXP3+Helios+ regulatory T cells, immune activation and advancing disease in HIV infected children. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 27003495 DOI: 10.1097/Qai.0000000000001000 |
0.577 |
|
| 2016 |
Diefenbach C, Raphael BG, Grossbard ML, Hymes KB, Moskovits T, Kaminetzky D, Martin P, Ruan J, McShea M, B'etou L, Bonakdar M, Abidoglu C, Kozhaya L, Leonard JP, Unutmaz D. Hodgkin Lymphoma Patients Demonstrate Evidence of Systemic Perturbation of the Monocyte-Dendritic Cell Axis Blood. 128: 2949-2949. DOI: 10.1182/Blood.V128.22.2949.2949 |
0.444 |
|
| 2016 |
Kwa M, Novik Y, Oratz R, Jhaveri K, Wu J, Gu P, Meyers M, Muggia F, Bonakdar M, Abidoglu C, Kozhaya L, Li X, Joseph B, Iwano A, Friedman K, ... ... Unutmaz D, et al. Abstract P2-11-11: Phase II trial of exemestane with immunomodulatory oral cyclophosphamide in metastatic hormone receptor (HR)-positive breast cancer: Prolonged progression-free survival (PFS) in patients with distinct T regulatory cell (Treg) profile Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P2-11-11 |
0.385 |
|
| 2016 |
Diefenbach CS, Raphael B, Hymes K, Grossbard M, Moskovits T, Kaminetzky D, Mcshea M, Martin P, Ruan J, Kozhaya L, Bonakdar M, Abidoglu C, Leonard J, Unutmaz D. Abstract 4895: Hodgkin lymphoma patients demonstrate evidence of chronic activation/exhaustion in circulating T cell subsets Cancer Research. 76: 4895-4895. DOI: 10.1158/1538-7445.Am2016-4895 |
0.506 |
|
| 2015 |
Kaufmann U, Shaw PJ, Kozhaya L, Subramanian R, Gaida K, Unutmaz D, McBride HJ, Feske S. Selective ORAI1 Inhibition Ameliorates Autoimmune Central Nervous System Inflammation by Suppressing Effector but Not Regulatory T Cell Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 26673135 DOI: 10.4049/Jimmunol.1501406 |
0.576 |
|
| 2015 |
Vaeth M, Zee I, Concepcion AR, Maus M, Shaw P, Portal-Celhay C, Zahra A, Kozhaya L, Weidinger C, Philips J, Unutmaz D, Feske S. Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells. Journal of Immunology (Baltimore, Md. : 1950). 195: 1202-17. PMID 26109647 DOI: 10.4049/Jimmunol.1403013 |
0.457 |
|
| 2015 |
VanCompernolle S, Smith PB, Bowie JH, Tyler MJ, Unutmaz D, Rollins-Smith LA. Inhibition of HIV infection by caerin 1 antimicrobial peptides. Peptides. PMID 26026377 DOI: 10.1016/J.Peptides.2015.05.004 |
0.505 |
|
| 2015 |
Rawlings SA, Alonzo F, Kozhaya L, Torres VJ, Unutmaz D. Elimination of HIV-1-Infected Primary T Cell Reservoirs in an In Vitro Model of Latency. Plos One. 10: e0126917. PMID 25993666 DOI: 10.1371/Journal.Pone.0126917 |
0.613 |
|
| 2015 |
Desvignes L, Weidinger C, Shaw P, Vaeth M, Ribierre T, Liu M, Fergus T, Kozhaya L, McVoy L, Unutmaz D, Ernst JD, Feske S. STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection. The Journal of Clinical Investigation. 125: 2347-62. PMID 25938788 DOI: 10.1172/Jci80273 |
0.57 |
|
| 2014 |
Mercer F, Khaitan A, Kozhaya L, Aberg JA, Unutmaz D. Differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors. Journal of Immunology (Baltimore, Md. : 1950). 193: 1047-54. PMID 24958901 DOI: 10.4049/Jimmunol.1302936 |
0.519 |
|
| 2014 |
Ramesh R, Kozhaya L, McKevitt K, Djuretic IM, Carlson TJ, Quintero MA, McCauley JL, Abreu MT, Unutmaz D, Sundrud MS. Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids. The Journal of Experimental Medicine. 211: 89-104. PMID 24395888 DOI: 10.1084/Jem.20130301 |
0.748 |
|
| 2014 |
Diefenbach CS, Raphael BG, Hymes KB, Moskovits T, Kaminetzky D, Martin P, Ruan J, Lauro S, Banks D, Brown K, Bonakdar M, Abidoglu C, Kozhaya L, Leonard JP, Unutmaz D. Circulating Memory T Cells Isolated from Hodgkin Lymphoma Patients Display Evidence of Exhaustion and Chronic Activation Blood. 124: 4400-4400. DOI: 10.1182/Blood.V124.21.4400.4400 |
0.514 |
|
| 2014 |
Dave UP, Palma N, Wang K, Reddy NM, Ali S, Tripathi R, Greenplate A, Irish JM, Unutmaz D, Stephens PJ, Miller VA. Comprehensive Hybrid Capture-Based Genomic Profiling of T-Cell Leukemias and Lymphomas Reveals Targetable JAK1 and JAK3 Co-Existing Mutations Blood. 124: 1672-1672. DOI: 10.1182/Blood.V124.21.1672.1672 |
0.474 |
|
| 2013 |
Zhou AX, El Hed A, Mercer F, Kozhaya L, Unutmaz D. The metalloprotease ADAM12 regulates the effector function of human Th17 cells. Plos One. 8: e81146. PMID 24363794 DOI: 10.1371/Journal.Pone.0081146 |
0.616 |
|
| 2013 |
Reyes-Robles T, Alonzo F, Kozhaya L, Lacy DB, Unutmaz D, Torres VJ. Staphylococcus aureus leukotoxin ED targets the chemokine receptors CXCR1 and CXCR2 to kill leukocytes and promote infection. Cell Host & Microbe. 14: 453-9. PMID 24139401 DOI: 10.1016/J.Chom.2013.09.005 |
0.434 |
|
| 2013 |
Edwards JP, Fujii H, Zhou AX, Creemers J, Unutmaz D, Shevach EM. Regulation of the expression of GARP/latent TGF-β1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation. Journal of Immunology (Baltimore, Md. : 1950). 190: 5506-15. PMID 23645881 DOI: 10.4049/Jimmunol.1300199 |
0.444 |
|
| 2013 |
Zhou AX, Kozhaya L, Fujii H, Unutmaz D. GARP-TGF-β complexes negatively regulate regulatory T cell development and maintenance of peripheral CD4+ T cells in vivo. Journal of Immunology (Baltimore, Md. : 1950). 190: 5057-64. PMID 23576681 DOI: 10.4049/Jimmunol.1300065 |
0.58 |
|
| 2013 |
Wan Q, Kozhaya L, Imberg K, Mercer F, Zhong S, Krogsgaard M, Unutmaz D. Probing the effector and suppressive functions of human T cell subsets using antigen-specific engineered T cell receptors. Plos One. 8: e56302. PMID 23437112 DOI: 10.1371/Journal.Pone.0056302 |
0.597 |
|
| 2013 |
Alonzo F, Kozhaya L, Rawlings SA, Reyes-Robles T, DuMont AL, Myszka DG, Landau NR, Unutmaz D, Torres VJ. CCR5 is a receptor for Staphylococcus aureus leukotoxin ED. Nature. 493: 51-5. PMID 23235831 DOI: 10.1038/Nature11724 |
0.515 |
|
| 2013 |
Oswald-Richter K, Grill SM, Shariat N, Leelawong M, Sundrud MS, Haas DW, Unutmaz D. Cytokine Secretion by Treg T-cells Plos Biology. DOI: 10.1371/Journal.Pbio.0020198.G002 |
0.779 |
|
| 2013 |
Wan Q, Kozhaya L, Imberg K, Mercer F, Zhong S, Krogsgaard M, Unutmaz D. Correction: Probing the Effector and Suppressive Functions of Human T Cell Subsets Using Antigen-Specific Engineered T Cell Receptors Plos One. 8. DOI: 10.1371/annotation/cbc71d72-f1a2-45de-9d4a-cb0c8dc076b5 |
0.451 |
|
| 2012 |
Ambrose Z, Lee K, Ndjomou J, Xu H, Oztop I, Matous J, Takemura T, Unutmaz D, Engelman A, Hughes SH, KewalRamani VN. Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection. Journal of Virology. 86: 4708-14. PMID 22301145 DOI: 10.1128/Jvi.05887-11 |
0.443 |
|
| 2011 |
Wan Q, Kozhaya L, ElHed A, Ramesh R, Carlson TJ, Djuretic IM, Sundrud MS, Unutmaz D. Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells. The Journal of Experimental Medicine. 208: 1875-87. PMID 21825017 DOI: 10.1084/Jem.20102516 |
0.726 |
|
| 2011 |
Mackey-Cushman SL, Gao J, Holmes DA, Nunoya JI, Wang R, Unutmaz D, Su L. FoxP3 interacts with linker histone H1.5 to modulate gene expression and program Treg cell activity. Genes and Immunity. 12: 559-67. PMID 21654845 DOI: 10.1038/Gene.2011.31 |
0.501 |
|
| 2011 |
Dumont AL, Nygaard TK, Watkins RL, Smith A, Kozhaya L, Kreiswirth BN, Shopsin B, Unutmaz D, Voyich JM, Torres VJ. Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis. Molecular Microbiology. 79: 814-25. PMID 21255120 DOI: 10.1111/J.1365-2958.2010.07490.X |
0.386 |
|
| 2011 |
Khaitan A, Unutmaz D. Revisiting immune exhaustion during HIV infection. Current Hiv/Aids Reports. 8: 4-11. PMID 21188556 DOI: 10.1007/S11904-010-0066-0 |
0.566 |
|
| 2011 |
Manel N, Hogstad B, Wang Y, Levy DE, Unutmaz D, Littman DR. A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells (Nature (2010) 467, (214-217)) Nature. 470: 424. DOI: 10.1038/nature09813 |
0.35 |
|
| 2010 |
Manel N, Hogstad B, Wang Y, Levy DE, Unutmaz D, Littman DR. A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells. Nature. 467: 214-7. PMID 20829794 DOI: 10.1038/Nature09337 |
0.589 |
|
| 2010 |
Elhed A, Unutmaz D. Th17 cells and HIV infection. Current Opinion in Hiv and Aids. 5: 146-50. PMID 20543592 DOI: 10.1097/Coh.0B013E32833647A8 |
0.524 |
|
| 2010 |
Lee K, Ambrose Z, Martin TD, Oztop I, Mulky A, Julias JG, Vandegraaff N, Baumann JG, Wang R, Yuen W, Takemura T, Shelton K, Taniuchi I, Li Y, Sodroski J, ... ... Unutmaz D, et al. Flexible use of nuclear import pathways by HIV-1. Cell Host & Microbe. 7: 221-33. PMID 20227665 DOI: 10.1016/J.Chom.2010.02.007 |
0.396 |
|
| 2010 |
El Hed A, Khaitan A, Kozhaya L, Manel N, Daskalakis D, Borkowsky W, Valentine F, Littman DR, Unutmaz D. Susceptibility of human Th17 cells to human immunodeficiency virus and their perturbation during infection. The Journal of Infectious Diseases. 201: 843-54. PMID 20144043 DOI: 10.1086/651021 |
0.546 |
|
| 2010 |
Furtak V, Mulky A, Rawlings SA, Kozhaya L, Lee K, Kewalramani VN, Unutmaz D. Perturbation of the P-body component Mov10 inhibits HIV-1 infectivity. Plos One. 5: e9081. PMID 20140200 DOI: 10.1371/Journal.Pone.0009081 |
0.461 |
|
| 2010 |
Mercer F, Kozhaya L, Unutmaz D. Expression and function of TNF and IL-1 receptors on human regulatory T cells. Plos One. 5: e8639. PMID 20066156 DOI: 10.1371/Journal.Pone.0008639 |
0.457 |
|
| 2009 |
Mercer F, Unutmaz D. The biology of FoxP3: a key player in immune suppression during infections, autoimmune diseases and cancer. Advances in Experimental Medicine and Biology. 665: 47-59. PMID 20429415 DOI: 10.1007/978-1-4419-1599-3_4 |
0.441 |
|
| 2009 |
Unutmaz D, Pulendran B. The gut feeling of Treg cells: IL-10 is the silver lining during colitis. Nature Immunology. 10: 1141-3. PMID 19841645 DOI: 10.1038/Ni1109-1141 |
0.502 |
|
| 2009 |
Wang R, Kozhaya L, Mercer F, Khaitan A, Fujii H, Unutmaz D. Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 13439-44. PMID 19666573 DOI: 10.1073/Pnas.0901965106 |
0.678 |
|
| 2009 |
Tran DQ, Andersson J, Wang R, Ramsey H, Unutmaz D, Shevach EM. GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 13445-50. PMID 19651619 DOI: 10.1073/Pnas.0901944106 |
0.326 |
|
| 2009 |
Unutmaz D. RORC2: the master of human Th17 cell programming. European Journal of Immunology. 39: 1452-5. PMID 19499530 DOI: 10.1002/Eji.200939540 |
0.534 |
|
| 2009 |
Sundrud MS, Koralov SB, Feuerer M, Calado DP, Kozhaya AE, Rhule-Smith A, Lefebvre RE, Unutmaz D, Mazitschek R, Waldner H, Whitman M, Keller T, Rao A. Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response. Science (New York, N.Y.). 324: 1334-8. PMID 19498172 DOI: 10.1126/Science.1172638 |
0.716 |
|
| 2009 |
Balato A, Unutmaz D, Gaspari AA. Natural killer T cells: an unconventional T-cell subset with diverse effector and regulatory functions. The Journal of Investigative Dermatology. 129: 1628-42. PMID 19262602 DOI: 10.1038/Jid.2009.30 |
0.597 |
|
| 2009 |
Vetter ML, Johnson ME, Antons AK, Unutmaz D, D'Aquila RT. Differences in APOBEC3G expression in CD4+ T helper lymphocyte subtypes modulate HIV-1 infectivity. Plos Pathogens. 5: e1000292. PMID 19197360 DOI: 10.1371/Journal.Ppat.1000292 |
0.838 |
|
| 2009 |
Camargo JF, Quinones MP, Mummidi S, Srinivas S, Gaitan AA, Begum K, Jimenez F, VanCompernolle S, Unutmaz D, Ahuja SS, Ahuja SK. CCR5 expression levels influence NFAT translocation, IL-2 production, and subsequent signaling events during T lymphocyte activation. Journal of Immunology (Baltimore, Md. : 1950). 182: 171-82. PMID 19109148 DOI: 10.4049/Jimmunol.182.1.171 |
0.578 |
|
| 2008 |
Faley S, Seale K, Hughey J, Schaffer DK, VanCompernolle S, McKinney B, Baudenbacher F, Unutmaz D, Wikswo JP. Microfluidic platform for real-time signaling analysis of multiple single T cells in parallel. Lab On a Chip. 8: 1700-12. PMID 18813394 DOI: 10.1039/B719799C |
0.527 |
|
| 2008 |
Antons AK, Wang R, Kalams SA, Unutmaz D. Suppression of HIV-specific and allogeneic T cell activation by human regulatory T cells is dependent on the strength of signals. Plos One. 3: e2952. PMID 18698349 DOI: 10.1371/Journal.Pone.0002952 |
0.829 |
|
| 2008 |
Wang R, Wan Q, Kozhaya L, Fujii H, Unutmaz D. Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression. Plos One. 3: e2705. PMID 18628982 DOI: 10.1371/Journal.Pone.0002705 |
0.598 |
|
| 2008 |
Jiang Q, Zhang L, Wang R, Jeffrey J, Washburn ML, Brouwer D, Barbour S, Kovalev GI, Unutmaz D, Su L. FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gammaC-/- mice in vivo. Blood. 112: 2858-68. PMID 18544681 DOI: 10.1182/Blood-2008-03-145946 |
0.617 |
|
| 2008 |
Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nature Immunology. 9: 641-9. PMID 18454151 DOI: 10.1038/Ni.1610 |
0.472 |
|
| 2008 |
Antons AK, Wang R, Oswald-Richter K, Tseng M, Arendt CW, Kalams SA, Unutmaz D. Naive precursors of human regulatory T cells require FoxP3 for suppression and are susceptible to HIV infection. Journal of Immunology (Baltimore, Md. : 1950). 180: 764-73. PMID 18178814 DOI: 10.4049/Jimmunol.180.2.764 |
0.842 |
|
| 2008 |
Unutmaz D, Vilcek J. IRF1: a deus ex machina in TH1 differentiation. Nature Immunology. 9: 9-10. PMID 18087248 DOI: 10.1038/Ni0108-9 |
0.4 |
|
| 2008 |
Gober MD, Fishelevich R, Zhao Y, Unutmaz D, Gaspari AA. Human natural killer T cells infiltrate into the skin at elicitation sites of allergic contact dermatitis. The Journal of Investigative Dermatology. 128: 1460-9. PMID 18079745 DOI: 10.1038/Sj.Jid.5701199 |
0.497 |
|
| 2007 |
Torres VJ, VanCompernolle SE, Sundrud MS, Unutmaz D, Cover TL. Helicobacter pylori vacuolating cytotoxin inhibits activation-induced proliferation of human T and B lymphocyte subsets. Journal of Immunology (Baltimore, Md. : 1950). 179: 5433-40. PMID 17911630 DOI: 10.4049/Jimmunol.179.8.5433 |
0.78 |
|
| 2007 |
Oswald-Richter K, Grill SM, Leelawong M, Tseng M, Kalams SA, Hulgan T, Haas DW, Unutmaz D. Identification of a CCR5-expressing T cell subset that is resistant to R5-tropic HIV infection. Plos Pathogens. 3: e58. PMID 17465678 DOI: 10.1371/Journal.Ppat.0030058 |
0.633 |
|
| 2007 |
Mummidi S, Adams LM, VanCompernolle SE, Kalkonde M, Camargo JF, Kulkarni H, Bellinger AS, Bonello G, Tagoh H, Ahuja SS, Unutmaz D, Ahuja SK. Production of specific mRNA transcripts, usage of an alternate promoter, and octamer-binding transcription factors influence the surface expression levels of the HIV coreceptor CCR5 on primary T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 5668-81. PMID 17442950 DOI: 10.4049/Jimmunol.178.9.5668 |
0.515 |
|
| 2007 |
Algood HM, Torres VJ, Unutmaz D, Cover TL. Resistance of primary murine CD4+ T cells to Helicobacter pylori vacuolating cytotoxin. Infection and Immunity. 75: 334-41. PMID 17074854 DOI: 10.1128/Iai.01063-06 |
0.564 |
|
| 2006 |
Eger KA, Sundrud MS, Motsinger AA, Tseng M, Van Kaer L, Unutmaz D. Human natural killer T cells are heterogeneous in their capacity to reprogram their effector functions. Plos One. 1: e50. PMID 17183680 DOI: 10.1371/Journal.Pone.0000050 |
0.796 |
|
| 2006 |
Srivastava S, Li Z, Ko K, Choudhury P, Albaqumi M, Johnson AK, Yan Y, Backer JM, Unutmaz D, Coetzee WA, Skolnik EY. Histidine phosphorylation of the potassium channel KCa3.1 by nucleoside diphosphate kinase B is required for activation of KCa3.1 and CD4 T cells. Molecular Cell. 24: 665-75. PMID 17157250 DOI: 10.1016/J.Molcel.2006.11.012 |
0.417 |
|
| 2006 |
Oswald-Richter K, Torres VJ, Sundrud MS, VanCompernolle SE, Cover TL, Unutmaz D. Helicobacter pylori VacA toxin inhibits human immunodeficiency virus infection of primary human T cells. Journal of Virology. 80: 11767-75. PMID 17005643 DOI: 10.1128/Jvi.00213-06 |
0.808 |
|
| 2006 |
Haas DW, Geraghty DE, Andersen J, Mar J, Motsinger AA, D'Aquila RT, Unutmaz D, Benson CA, Ritchie MD, Landay A. Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: An AIDS Clinical Trials Group study. The Journal of Infectious Diseases. 194: 1098-107. PMID 16991084 DOI: 10.1086/507313 |
0.379 |
|
| 2006 |
Bezbradica JS, Gordy LE, Stanic AK, Dragovic S, Hill T, Hawiger J, Unutmaz D, Van Kaer L, Joyce S. Granulocyte-macrophage colony-stimulating factor regulates effector differentiation of invariant natural killer T cells during thymic ontogeny. Immunity. 25: 487-97. PMID 16949316 DOI: 10.1016/J.Immuni.2006.06.017 |
0.511 |
|
| 2006 |
Srivastava S, Ko K, Choudhury P, Li Z, Johnson AK, Nadkarni V, Unutmaz D, Coetzee WA, Skolnik EY. Phosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cells. Molecular and Cellular Biology. 26: 5595-602. PMID 16847315 DOI: 10.1128/Mcb.00352-06 |
0.494 |
|
| 2006 |
Dillon S, Agrawal S, Banerjee K, Letterio J, Denning TL, Oswald-Richter K, Kasprowicz DJ, Kellar K, Pare J, van Dyke T, Ziegler S, Unutmaz D, Pulendran B. Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance. The Journal of Clinical Investigation. 116: 916-28. PMID 16543948 DOI: 10.1172/Jci27203 |
0.399 |
|
| 2005 |
VanCompernolle SE, Taylor RJ, Oswald-Richter K, Jiang J, Youree BE, Bowie JH, Tyler MJ, Conlon JM, Wade D, Aiken C, Dermody TS, KewalRamani VN, Rollins-Smith LA, Unutmaz D. Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells. Journal of Virology. 79: 11598-606. PMID 16140737 DOI: 10.1128/Jvi.79.18.11598-11606.2005 |
0.477 |
|
| 2005 |
Sundrud MS, Vancompernolle SE, Eger KA, Bruno TC, Subramaniam A, Mummidi S, Ahuja SK, Unutmaz D. Transcription factor GATA-1 potently represses the expression of the HIV-1 coreceptor CCR5 in human T cells and dendritic cells. Blood. 106: 3440-8. PMID 16091457 DOI: 10.1182/Blood-2005-03-0857 |
0.816 |
|
| 2005 |
Eger KA, Unutmaz D. The innate immune system and HIV pathogenesis. Current Hiv/Aids Reports. 2: 10-5. PMID 16091243 DOI: 10.1007/S11904-996-0003-4 |
0.785 |
|
| 2005 |
Bezbradica JS, Stanic AK, Matsuki N, Bour-Jordan H, Bluestone JA, Thomas JW, Unutmaz D, Van Kaer L, Joyce S. Distinct roles of dendritic cells and B cells in Va14Ja18 natural T cell activation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 174: 4696-705. PMID 15814694 DOI: 10.4049/Jimmunol.174.8.4696 |
0.531 |
|
| 2005 |
Chen J, Dang Q, Unutmaz D, Pathak VK, Maldarelli F, Powell D, Hu WS. Mechanisms of nonrandom human immunodeficiency virus type 1 infection and double infection: preference in virus entry is important but is not the sole factor. Journal of Virology. 79: 4140-9. PMID 15767415 DOI: 10.1128/Jvi.79.7.4140-4149.2005 |
0.518 |
|
| 2004 |
Baumann JG, Unutmaz D, Miller MD, Breun SK, Grill SM, Mirro J, Littman DR, Rein A, KewalRamani VN. Murine T cells potently restrict human immunodeficiency virus infection. Journal of Virology. 78: 12537-47. PMID 15507641 DOI: 10.1128/Jvi.78.22.12537-12547.2004 |
0.577 |
|
| 2004 |
Yu Q, Chen D, König R, Mariani R, Unutmaz D, Landau NR. APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication. The Journal of Biological Chemistry. 279: 53379-86. PMID 15466872 DOI: 10.1074/Jbc.M408802200 |
0.402 |
|
| 2004 |
Oswald-Richter K, Grill SM, Shariat N, Leelawong M, Sundrud MS, Haas DW, Unutmaz D. HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells. Plos Biology. 2: E198. PMID 15252446 DOI: 10.1371/Journal.Pbio.0020198 |
0.832 |
|
| 2004 |
Eger KA, Unutmaz D. Perturbation of natural killer cell function and receptors during HIV infection. Trends in Microbiology. 12: 301-3. PMID 15223055 DOI: 10.1016/j.tim.2004.05.006 |
0.806 |
|
| 2004 |
Oswald-Richter K, Grill SM, Leelawong M, Unutmaz D. HIV infection of primary human T cells is determined by tunable thresholds of T cell activation. European Journal of Immunology. 34: 1705-14. PMID 15162441 DOI: 10.1002/Eji.200424892 |
0.623 |
|
| 2004 |
Sundrud MS, Torres VJ, Unutmaz D, Cover TL. Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion. Proceedings of the National Academy of Sciences of the United States of America. 101: 7727-32. PMID 15128946 DOI: 10.1073/Pnas.0401528101 |
0.783 |
|
| 2004 |
Dang Q, Chen J, Unutmaz D, Coffin JM, Pathak VK, Powell D, KewalRamani VN, Maldarelli F, Hu WS. Nonrandom HIV-1 infection and double infection via direct and cell-mediated pathways. Proceedings of the National Academy of Sciences of the United States of America. 101: 632-7. PMID 14707263 DOI: 10.1073/Pnas.0307636100 |
0.505 |
|
| 2003 |
Hulgan T, Donahue JP, Hawkins C, Unutmaz D, D'Aquila RT, Raffanti S, Nicotera F, Rebeiro P, Erdem H, Rueff M, Haas DW. Implications of T-cell P-glycoprotein activity during HIV-1 infection and its therapy. Journal of Acquired Immune Deficiency Syndromes (1999). 34: 119-26. PMID 14526200 DOI: 10.1097/00126334-200310010-00001 |
0.478 |
|
| 2003 |
Sundrud MS, Grill SM, Ni D, Nagata K, Alkan SS, Subramaniam A, Unutmaz D. Genetic reprogramming of primary human T cells reveals functional plasticity in Th cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 171: 3542-9. PMID 14500650 DOI: 10.4049/Jimmunol.171.7.3542 |
0.791 |
|
| 2003 |
Unutmaz D. NKT cells and HIV infection. Microbes and Infection / Institut Pasteur. 5: 1041-7. PMID 12941396 DOI: 10.1016/S1286-4579(03)00185-0 |
0.632 |
|
| 2003 |
Jo D, Lin Q, Nashabi A, Mays DJ, Unutmaz D, Pietenpol JA, Ruley HE. Cell cycle-dependent transduction of cell-permeant Cre recombinase proteins. Journal of Cellular Biochemistry. 89: 674-87. PMID 12858334 DOI: 10.1002/Jcb.10542 |
0.42 |
|
| 2003 |
Motsinger A, Azimzadeh A, Stanic AK, Johnson RP, Van Kaer L, Joyce S, Unutmaz D. Identification and simian immunodeficiency virus infection of CD1d-restricted macaque natural killer T cells. Journal of Virology. 77: 8153-8. PMID 12829854 DOI: 10.1128/Jvi.77.14.8153-8158.2003 |
0.652 |
|
| 2003 |
McDonald D, Wu L, Bohks SM, KewalRamani VN, Unutmaz D, Hope TJ. Recruitment of HIV and its receptors to dendritic cell-T cell junctions. Science (New York, N.Y.). 300: 1295-7. PMID 12730499 DOI: 10.1126/Science.1084238 |
0.604 |
|
| 2003 |
Donahue JP, Dowdy D, Ratnam KK, Hulgan T, Price J, Unutmaz D, Nicotera J, Raffanti S, Becker M, Haas DW. Effects of nelfinavir and its M8 metabolite on lymphocyte P-glycoprotein activity during antiretroviral therapy. Clinical Pharmacology and Therapeutics. 73: 78-86. PMID 12545146 DOI: 10.1067/Mcp.2003.11 |
0.417 |
|
| 2002 |
Jung S, Unutmaz D, Wong P, Sano G, De los Santos K, Sparwasser T, Wu S, Vuthoori S, Ko K, Zavala F, Pamer EG, Littman DR, Lang RA. In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity. 17: 211-20. PMID 12196292 DOI: 10.1016/S1074-7613(02)00365-5 |
0.501 |
|
| 2002 |
Wu L, Martin TD, Vazeux R, Unutmaz D, KewalRamani VN. Functional evaluation of DC-SIGN monoclonal antibodies reveals DC-SIGN interactions with ICAM-3 do not promote human immunodeficiency virus type 1 transmission. Journal of Virology. 76: 5905-14. PMID 12021323 DOI: 10.1128/Jvi.76.12.5905-5914.2002 |
0.481 |
|
| 2002 |
Lundquist CA, Tobiume M, Zhou J, Unutmaz D, Aiken C. Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes. Journal of Virology. 76: 4625-33. PMID 11932428 DOI: 10.1128/Jvi.76.9.4625-4633.2002 |
0.609 |
|
| 2002 |
Motsinger A, Haas DW, Stanic AK, Van Kaer L, Joyce S, Unutmaz D. CD1d-restricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infection. The Journal of Experimental Medicine. 195: 869-79. PMID 11927631 DOI: 10.1084/Jem.20011712 |
0.66 |
|
| 2002 |
Wu L, Bashirova AA, Martin TD, Villamide L, Mehlhop E, Chertov AO, Unutmaz D, Pope M, Carrington M, KewalRamani VN. Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN. Proceedings of the National Academy of Sciences of the United States of America. 99: 1568-73. PMID 11818554 DOI: 10.1073/Pnas.032654399 |
0.426 |
|
| 2001 |
Jo D, Nashabi A, Doxsee C, Lin Q, Unutmaz D, Chen J, Ruley HE. Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase. Nature Biotechnology. 19: 929-33. PMID 11581657 DOI: 10.1038/Nbt1001-929 |
0.358 |
|
| 2001 |
Unutmaz D. T cell signaling mechanisms that regulate HIV-1 infection Immunologic Research. 23: 167-177. PMID 11444382 DOI: 10.1385/Ir:23:2-3:167 |
0.551 |
|
| 2001 |
Campbell JJ, Qin S, Unutmaz D, Soler D, Murphy KE, Hodge MR, Wu L, Butcher EC. Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire Journal of Immunology. 166: 6477-6482. PMID 11359797 DOI: 10.4049/Jimmunol.166.11.6477 |
0.506 |
|
| 2000 |
Unutmaz D, Xiang W, Sunshine MJ, Campbell J, Butcher E, Littman DR. The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse Journal of Immunology. 165: 3284-3292. PMID 10975845 DOI: 10.4049/Jimmunol.165.6.3284 |
0.539 |
|
| 2000 |
Sun Z, Unutmaz D, Zou YR, Sunshine MJ, Pierani A, Brenner-Morton S, Mebius RE, Littman DR. Requirement for RORgamma in thymocyte survival and lymphoid organ development. Science (New York, N.Y.). 288: 2369-73. PMID 10875923 DOI: 10.1126/Science.288.5475.2369 |
0.436 |
|
| 1999 |
Unutmaz D, KewalRamani VN, Marmon S, Littman DR. Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes Journal of Experimental Medicine. 189: 1735-1746. PMID 10359577 DOI: 10.1084/Jem.189.11.1735 |
0.646 |
|
| 1998 |
Hill CM, Kwon D, Jones M, Davis CB, Marmon S, Daugherty BL, DeMartino JA, Springer MS, Unutmaz D, Littman DR. The amino terminus of human CCR5 is required for its function as a receptor for diverse human and simian immunodeficiency virus envelope glycoproteins. Virology. 248: 357-71. PMID 9721244 DOI: 10.1006/Viro.1998.9283 |
0.523 |
|
| 1998 |
Unutmaz D, KewalRamani VN, Littman DR. G protein-coupled receptors in HIV and SIV entry: New perspectives on lentivirus-host interactions and on the utility of animal models Seminars in Immunology. 10: 225-236. PMID 9653049 DOI: 10.1006/Smim.1998.0134 |
0.406 |
|
| 1997 |
Davis CB, Dikic I, Unutmaz D, Hill CM, Arthos J, Siani MA, Thompson DA, Schlessinger J, Littman DR. Signal transduction due to HIV-1 envelope interactions with chemokine receptors CXCR4 or CCR5. The Journal of Experimental Medicine. 186: 1793-8. PMID 9362541 DOI: 10.1084/Jem.186.10.1793 |
0.486 |
|
| 1997 |
Hill CM, Deng H, Unutmaz D, Kewalramani VN, Bastiani L, Gorny MK, Zolla-Pazner S, Littman DR. Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions with this chemokine receptor Journal of Virology. 71: 6296-6304. PMID 9261346 DOI: 10.1128/Jvi.71.9.6296-6304.1997 |
0.473 |
|
| 1997 |
Deng H, Unutmaz D, Kewalramani VN, Littman DR. Expression cloning of new receptors used by simian and human immunodeficiency viruses Nature. 388: 296-300. PMID 9230441 DOI: 10.1038/40894 |
0.476 |
|
| 1997 |
Unutmaz D, Littman DR. Expression pattern of HIV-1 coreceptors on T cells: Implications for viral transmission and lymphocyte homing Proceedings of the National Academy of Sciences of the United States of America. 94: 1615-1618. PMID 9050826 DOI: 10.1073/Pnas.94.5.1615 |
0.555 |
|
| 1996 |
Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, Di Marzio P, Marmon S, Sutton RE, Mark Hill C, Davis CB, Peiper SC, Schall TJ, Littman DR, Landau NR. Identification of a major co-receptor for primary isolates of HIV-1 Nature. 381: 661-666. PMID 8649511 DOI: 10.1038/381661A0 |
0.529 |
|
| 1995 |
Unutmaz D, Baldoni F, Abrignani S. Human naive T cells activated by cytokines differentiate into a split phenotype with functional features intermediate between naive and memory T cells International Immunology. 7: 1417-1424. PMID 7495749 DOI: 10.1093/Intimm/7.9.1417 |
0.612 |
|
| 1994 |
Unutmaz D, Pileri P, Abrignani S. Antigen-independent activation of naive and memory resting T cells by a cytokine combination Journal of Experimental Medicine. 180: 1159-1164. PMID 8064232 DOI: 10.1084/Jem.180.3.1159 |
0.578 |
|
| 1993 |
Botarelli P, Brunetto MR, Minutello MA, Calvo P, Unutmaz D, Weiner AJ, Choo Ql, Shuster JR, Kuo G, Bonino F, Houghton M, Abrignam S. T-lymphocyte response to hepatitis C virus in different clinical courses of infection Gastroenterology. 104: 580-587. PMID 8425701 DOI: 10.1016/0016-5085(93)90430-K |
0.474 |
|
| 1993 |
Minutello MA, Pileri P, Unutmaz D, Censini S, Kuo G, Houghton M, Brunetto MR, Bonino F, Abrignani S. Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C. The Journal of Experimental Medicine. 178: 17-25. PMID 8100267 DOI: 10.1084/Jem.178.1.17 |
0.496 |
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