Hasan Uludag - Publications

Affiliations: 
Biomedical Engineering University of Alberta, Edmonton, Alberta, Canada 
Area:
Biomedical Engineering

151 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Uludağ H, Parent K, Aliabadi HM, Haddadi A. Prospects for RNAi Therapy of COVID-19. Frontiers in Bioengineering and Biotechnology. 8: 916. PMID 32850752 DOI: 10.3389/Fbioe.2020.00916  0.309
2020 Plianwong S, Thapa B, Kc RB, Kucharski C, Rojanarata T, Uludağ H. Enabling Combinatorial siRNA Delivery against Apoptosis-Related Proteins with Linoleic Acid and α-Linoleic Acid Substituted Low Molecular Weight Polyethylenimines. Pharmaceutical Research. 37: 46. PMID 32016611 DOI: 10.1007/S11095-020-2770-9  0.347
2020 Pankongadisak P, Tsekoura E, Suwantong O, Uludağ H. Electrospun gelatin matrices with bioactive pDNA polyplexes. International Journal of Biological Macromolecules. 149: 296-308. PMID 31991211 DOI: 10.1016/J.Ijbiomac.2020.01.252  0.368
2019 Aliabadi HM, Bahadur K C R, Bousoik E, Hall R, Barbarino A, Thapa B, Coyle M, Mahdipoor P, Uludağ H. A Systematic Comparison of Lipopolymers for siRNA Delivery to Multiple Breast Cancer Cell Lines: In vitro Studies. Acta Biomaterialia. PMID 31760224 DOI: 10.1016/J.Actbio.2019.11.036  0.322
2019 Remant KC, Thapa B, Valencia-Serna J, Domun SS, Dimitroff C, Jiang X, Uludağ H. Cholesterol Grafted Cationic Lipopolymers: Potential siRNA Carriers for Selective Chronic Myeloid Leukemia (CML) Therapy. Journal of Biomedical Materials Research. Part A. PMID 31714657 DOI: 10.1002/Jbm.A.36837  0.376
2019 Thapa B, Kc R, Hitt M, Lavasanifar A, Kutsch O, Seol DW, Uludag H. Breathing New Life into TRAIL for Breast Cancer Therapy: Co-delivery of pTRAIL and Complementary siRNAs using Lipopolymers. Human Gene Therapy. PMID 31547718 DOI: 10.1089/Hum.2019.096  0.334
2019 Valencia-Serna J, Kucharski C, Chen M, Remant KC, Jiang X, Brandwein J, Uludağ H. siRNA-mediated BCR-ABL silencing in primary chronic myeloid leukemia cells using Lipopolymers. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31430499 DOI: 10.1016/J.Jconrel.2019.08.018  0.349
2019 Uludag H, Ubeda A, Ansari A. At the Intersection of Biomaterials and Gene Therapy: Progress in Non-viral Delivery of Nucleic Acids. Frontiers in Bioengineering and Biotechnology. 7: 131. PMID 31214586 DOI: 10.3389/Fbioe.2019.00131  0.312
2019 Thapa B, Remant KC, Uludağ H. siRNA Library Screening to Identify Complementary Therapeutic Pairs in Triple-Negative Breast Cancer Cells. Methods in Molecular Biology (Clifton, N.J.). 1974: 1-19. PMID 31098991 DOI: 10.1007/978-1-4939-9220-1_1  0.308
2018 Wubneh A, Tsekoura E, Ayranci C, Uludağ H. Current State of Fabrication Technologies and Materials for Bone Tissue Engineering. Acta Biomaterialia. PMID 30248515 DOI: 10.1016/J.Actbio.2018.09.031  0.44
2018 Parmar MB, K C RB, Löbenberg R, Uludag H. Additive polyplexes to undertake siRNA therapy against CDC20 and survivin in breast cancer cells. Biomacromolecules. PMID 30222931 DOI: 10.1021/Acs.Biomac.8B00918  0.364
2018 Meneksedag-Erol D, Kizhakkedathu JN, Tang T, Uludag H. Molecular Dynamics Simulations on Nucleic Acid Binding Polymers Designed to Arrest Thrombosis. Acs Applied Materials & Interfaces. PMID 30085650 DOI: 10.1021/Acsami.8B09914  0.324
2018 Kaur H, Siraki AG, Sharma M, Uludağ H, Dederich DN, Flood P, El-Bialy T. Reactive Oxygen Species Mediate Therapeutic Ultrasound-Induced, Mitogen-Activated Protein Kinase Activation in C28/I2 Chondrocytes. Ultrasound in Medicine & Biology. PMID 30037475 DOI: 10.1016/J.Ultrasmedbio.2018.05.025  0.331
2018 Valencia-Serna J, Aliabadi HM, Manfrin A, Mohseni M, Jiang X, Uludag H. siRNA/Lipopolymer Nanoparticles to Arrest Growth of Chronic Myeloid Leukemia Cells In Vitro and In Vivo. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 29913272 DOI: 10.1016/J.Ejpb.2018.06.018  0.373
2018 Sezlev Bilecen D, Uludag H, Hasirci V. Development of PEI-RANK siRNA Complex Loaded PLGA Nanocapsules for the Treatment of Osteoporosis. Tissue Engineering. Part A. PMID 29652606 DOI: 10.1089/Ten.Tea.2017.0476  0.469
2018 Parmar MB, Meenakshi Sundaram DN, K C RB, Maranchuk R, Montazeri Aliabadi H, Hugh JC, Löbenberg R, Uludağ H. Combinational siRNA delivery using hyaluronic acid modified amphiphilic polyplexes against cell cycle and phosphatase proteins to inhibit growth and migration of triple-negative breast cancer cells. Acta Biomaterialia. 66: 294-309. PMID 29183848 DOI: 10.1016/J.Actbio.2017.11.036  0.332
2017 Tsekoura EK, K C RB, Uludag H. Biomaterials to Facilitate Delivery of RNA Agents in Bone Regeneration and Repair. Acs Biomaterials Science & Engineering. 3: 1195-1206. PMID 33440509 DOI: 10.1021/acsbiomaterials.6b00387  0.3
2017 Ansari AS, Santerre PJ, Uludağ H. Biomaterials for polynucleotide delivery to anchorage-independent cells. Journal of Materials Chemistry. B. 5: 7238-7261. PMID 32264174 DOI: 10.1039/C7Tb01833A  0.335
2017 Meneksedag-Erol D, Tang T, Uludağ H. Mechanistic insights into the role of glycosaminoglycans in delivery of polymeric nucleic acid nanoparticles by molecular dynamics simulations. Biomaterials. 156: 107-120. PMID 29195180 DOI: 10.1016/J.Biomaterials.2017.11.037  0.325
2017 Thapa B, Bahadur Kc R, Uludağ H. Novel Targets for Sensitizing Breast Cancer Cells to TRAIL-Induced Apoptosis with siRNA Delivery. International Journal of Cancer. PMID 28960310 DOI: 10.1002/Ijc.31079  0.33
2017 Sezlev Bilecen D, Rodriguez-Cabello JC, Uludag H, Hasirci V. Construction of a PLGA Based, Targeted siRNA Delivery System for Treatment of Osteoporosis. Journal of Biomaterials Science. Polymer Edition. 1-31. PMID 28722515 DOI: 10.1080/09205063.2017.1354675  0.473
2017 Remant Bahadur KC, Thapa B, Valencia-Serna J, Aliabadi HM, Uludağ H. Nucleic acid combinations: A new frontier for cancer treatment. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28450205 DOI: 10.1016/J.Jconrel.2017.04.029  0.309
2017 Meenakshi Sundaram DN, Kucharski C, Parmar MB, Kc RB, Uludağ H. Polymeric Delivery of siRNA against Integrin-β1 (CD29) to Reduce Attachment and Migration of Breast Cancer Cells. Macromolecular Bioscience. PMID 28160423 DOI: 10.1002/Mabi.201600430  0.324
2017 Pezzoli D, Tsekoura EK, Remant Bahadur K, Candiani G, Mantovani D, Uludağ H. Hydrophobe-substituted bPEI derivatives: boosting transfection on primary vascular cells Science China Materials. 60: 529-542. DOI: 10.1007/S40843-017-9030-7  0.347
2016 Kaur H, Uludağ H, Dederich DN, El-Bialy T. Effect of Increasing Low-Intensity Pulsed Ultrasound and a Functional Appliance on the Mandibular Condyle in Growing Rats. Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. PMID 27925675 DOI: 10.7863/Ultra.15.06063  0.309
2016 Aliabadi HM, Mahdipoor P, Bisoffi M, Hugh JC, Uludag H. Single and Combinational siRNA Therapy of Cancer Cells: Probing Changes in Targeted and non-Targeted Mediators after siRNA Treatment. Molecular Pharmaceutics. PMID 27802596 DOI: 10.1021/Acs.Molpharmaceut.6B00711  0.32
2016 Parmar MB, Arteaga Ballesteros BE, Fu T, Bahadur Kc R, Aliabadi HM, Hugh JC, Löbenberg R, Uludağ H. Multiple siRNA delivery against cell cycle and anti-apoptosis proteins using lipid-substituted polyethylenimine in triple-negative breast cancer and non-malignant cells. Journal of Biomedical Materials Research. Part A. PMID 27465922 DOI: 10.1002/Jbm.A.35846  0.385
2016 Uludağ H, Landry B, Valencia-Serna J, Remant-Bahadur KC, Meneksedağ-Erol D. Current attempts to implement siRNA-based RNAi in leukemia models. Drug Discovery Today. PMID 27126778 DOI: 10.1016/J.Drudis.2016.04.018  0.324
2016 Thapa B, Plianwong S, Remant Bahadur KC, Rutherford B, Uludağ H. Small hydrophobe substitution on polyethylenimine for plasmid DNA delivery: Optimal substitution is critical for effective delivery. Acta Biomaterialia. PMID 26802444 DOI: 10.1016/J.Actbio.2016.01.025  0.393
2016 Landry B, Gül-Uludağ H, Plianwong S, Kucharski C, Zak Z, Parmar MB, Kutsch O, Jiang H, Brandwein J, Uludağ H. Targeting CXCR4/SDF-1 axis by lipopolymer complexes of siRNA in acute myeloid leukemia. Journal of Controlled Release : Official Journal of the Controlled Release Society. 224: 8-21. PMID 26742943 DOI: 10.1016/J.Jconrel.2015.12.052  0.438
2016 Tsekoura EK, K.C. RB, Uludag H. Biomaterials to Facilitate Delivery of RNA Agents in Bone Regeneration and Repair Acs Biomaterials Science & Engineering. 3: 1195-1206. DOI: 10.1021/Acsbiomaterials.6B00387  0.425
2015 Meneksedag-Erol D, Kc RB, Tang T, Uludağ H. A Delicate Balance When Substituting a Small Hydrophobe onto Low Molecular Weight Polyethylenimine to Improve Its Nucleic Acid Delivery Efficiency. Acs Applied Materials & Interfaces. 7: 24822-32. PMID 26493098 DOI: 10.1021/Acsami.5B07929  0.321
2015 Landry B, Valencia-Serna J, Gul-Uludag H, Jiang X, Janowska-Wieczorek A, Brandwein J, Uludag H. Progress in RNAi-mediated Molecular Therapy of Acute and Chronic Myeloid Leukemia. Molecular Therapy. Nucleic Acids. 4: e240. PMID 25965550 DOI: 10.1038/Mtna.2015.13  0.312
2015 Parmar MB, Aliabadi HM, Mahdipoor P, Kucharski C, Maranchuk R, Hugh JC, Uludağ H. Targeting Cell Cycle Proteins in Breast Cancer Cells with siRNA by Using Lipid-Substituted Polyethylenimines. Frontiers in Bioengineering and Biotechnology. 3: 14. PMID 25763370 DOI: 10.3389/Fbioe.2015.00014  0.368
2015 Aliabadi HM, Mahdipoor P, Uludag H. Abstract B45: A search for ideal siRNA targets involved in pathway cross-talks for combinational silencing in human cancer cells Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-B45  0.336
2015 Aliabadi HM, Mahdipoor P, Kucharsky C, Chan N, Uludag H. Abstract A57: Effects of pre-exposure to siRNA on silencing response: Do cells become resistant to siRNA silencing? Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-A57  0.304
2015 Aliabadi HM, Mahdipoor P, Uludag H. Abstract B15: In vivo analysis of repeated siRNA silencing on protein expression levels Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Tumang15-B15  0.35
2015 Valencia-Serna J, Remant K, Yang X, Aliabadi HM, Parmar MB, Jiang X, Uludag H. 156. Cationic Lipopolymers for BCR-ABL siRNA Delivery and Growth Arrest in Chronic Myeloid Leukemia Tumors Molecular Therapy. 23: S62-S63. DOI: 10.1016/S1525-0016(16)33761-3  0.418
2014 Rose L, Mahdipoor P, Kucharski C, Uludağ H. Pharmacokinetics and transgene expression of implanted polyethylenimine-based pDNA complexes. Biomaterials Science. 2: 833-42. PMID 26827752 DOI: 10.1039/C3Bm60200A  0.333
2014 Gul-Uludağ H, Valencia-Serna J, Kucharski C, Marquez-Curtis LA, Jiang X, Larratt L, Janowska-Wieczorek A, Uludağ H. Polymeric nanoparticle-mediated silencing of CD44 receptor in CD34+ acute myeloid leukemia cells. Leukemia Research. 38: 1299-308. PMID 25262448 DOI: 10.1016/J.Leukres.2014.08.008  0.314
2014 Kaur H, Uludağ H, El-Bialy T. Effect of nonviral plasmid delivered basic fibroblast growth factor and low intensity pulsed ultrasound on mandibular condylar growth: a preliminary study. Biomed Research International. 2014: 426710. PMID 24967367 DOI: 10.1155/2014/426710  0.374
2014 Meneksedag-Erol D, Tang T, Uludağ H. Molecular modeling of polynucleotide complexes. Biomaterials. 35: 7068-76. PMID 24856107 DOI: 10.1016/J.Biomaterials.2014.04.103  0.346
2013 Aliabadi HM, Maranchuk R, Kucharski C, Mahdipoor P, Hugh J, Uludağ H. Effective response of doxorubicin-sensitive and -resistant breast cancer cells to combinational siRNA therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 219-28. PMID 23994345 DOI: 10.1016/J.Jconrel.2013.08.012  0.319
2013 Dube B, Rose L, Sawant K, Uludag H. Cholic acid modified 2 kDa polyethylenimine as efficient transfection agent. Biotechnology Progress. 29: 1337-41. PMID 23955845 DOI: 10.1002/Btpr.1799  0.385
2013 Valencia-Serna J, Gul-Uludağ H, Mahdipoor P, Jiang X, Uludağ H. Investigating siRNA delivery to chronic myeloid leukemia K562 cells with lipophilic polymers for therapeutic BCR-ABL down-regulation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 495-503. PMID 23726887 DOI: 10.1016/J.Jconrel.2013.05.014  0.392
2013 Rose L, Uludağ H. Realizing the potential of gene-based molecular therapies in bone repair. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 2245-62. PMID 23553878 DOI: 10.1002/Jbmr.1944  0.486
2013 Rose L, Aliabadi HM, Uludağ H. Gelatin coating to stabilize the transfection ability of nucleic acid polyplexes. Acta Biomaterialia. 9: 7429-38. PMID 23542234 DOI: 10.1016/J.Actbio.2013.03.029  0.311
2013 Aliabadi HM, Mahdipoor P, Uludağ H. Polymeric delivery of siRNA for dual silencing of Mcl-1 and P-glycoprotein and apoptosis induction in drug-resistant breast cancer cells. Cancer Gene Therapy. 20: 169-77. PMID 23449477 DOI: 10.1038/Cgt.2013.8  0.334
2013 Wang Y, Mostafa NZ, Hsu CY, Rose L, Kucharki C, Yan J, Jiang H, Uludağ H. Modification of human BMSC with nanoparticles of polymeric biomaterials and plasmid DNA for BMP-2 secretion. The Journal of Surgical Research. 183: 8-17. PMID 23290528 DOI: 10.1016/J.Jss.2012.11.061  0.595
2013 Rose LC, Fitzsimmons R, Lee P, Krawetz R, Rancourt DE, Uludağ H. Effect of basic fibroblast growth factor in mouse embryonic stem cell culture and osteogenic differentiation. Journal of Tissue Engineering and Regenerative Medicine. 7: 371-82. PMID 22674886 DOI: 10.1002/Term.532  0.329
2012 Landry B, Aliabadi HM, Samuel A, Gül-Uludağ H, Jiang X, Kutsch O, Uludağ H. Effective non-viral delivery of siRNA to acute myeloid leukemia cells with lipid-substituted polyethylenimines. Plos One. 7: e44197. PMID 22952927 DOI: 10.1371/Journal.Pone.0044197  0.409
2012 Yogasundaram H, Bahniuk MS, Singh HD, Aliabadi HM, Uludağ H, Unsworth LD. BSA Nanoparticles for siRNA Delivery: Coating Effects on Nanoparticle Properties, Plasma Protein Adsorption, and In Vitro siRNA Delivery. International Journal of Biomaterials. 2012: 584060. PMID 22919392 DOI: 10.1155/2012/584060  0.338
2012 Hsu CY, Uludağ H. Cellular uptake pathways of lipid-modified cationic polymers in gene delivery to primary cells. Biomaterials. 33: 7834-48. PMID 22874502 DOI: 10.1016/J.Biomaterials.2012.06.093  0.557
2012 Fitzsimmons RE, Uludağ H. Specific effects of PEGylation on gene delivery efficacy of polyethylenimine: interplay between PEG substitution and N/P ratio. Acta Biomaterialia. 8: 3941-55. PMID 22820308 DOI: 10.1016/J.Actbio.2012.07.015  0.358
2012 Chen C, Uludağ H, Wang Z, Jiang H. Noggin suppression decreases BMP-2-induced osteogenesis of human bone marrow-derived mesenchymal stem cells in vitro. Journal of Cellular Biochemistry. 113: 3672-80. PMID 22740073 DOI: 10.1002/Jcb.24240  0.43
2012 Hsu CY, Uludağ H. A simple and rapid nonviral approach to efficiently transfect primary tissue-derived cells using polyethylenimine. Nature Protocols. 7: 935-45. PMID 22517260 DOI: 10.1038/Nprot.2012.038  0.567
2012 Aliabadi HM, Landry B, Mahdipoor P, Hsu CY, Uludağ H. Effective down-regulation of breast cancer resistance protein (BCRP) by siRNA delivery using lipid-substituted aliphatic polymers. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 81: 33-42. PMID 22311298 DOI: 10.1016/J.Ejpb.2012.01.011  0.568
2012 Hsu CY, Uludağ H. Nucleic-acid based gene therapeutics: delivery challenges and modular design of nonviral gene carriers and expression cassettes to overcome intracellular barriers for sustained targeted expression. Journal of Drug Targeting. 20: 301-28. PMID 22303844 DOI: 10.3109/1061186X.2012.655247  0.546
2012 Rose LC, Kucharski C, Uludağ H. Protein expression following non-viral delivery of plasmid DNA coding for basic FGF and BMP-2 in a rat ectopic model. Biomaterials. 33: 3363-74. PMID 22289263 DOI: 10.1016/J.Biomaterials.2012.01.031  0.483
2012 Wang G, Mostafa NZ, Incani V, Kucharski C, Uludağ H. Bisphosphonate-decorated lipid nanoparticles designed as drug carriers for bone diseases. Journal of Biomedical Materials Research. Part A. 100: 684-93. PMID 22213565 DOI: 10.1002/Jbm.A.34002  0.493
2012 Aliabadi HM, Landry B, Sun C, Tang T, Uludağ H. Supramolecular assemblies in functional siRNA delivery: where do we stand? Biomaterials. 33: 2546-69. PMID 22209641 DOI: 10.1016/J.Biomaterials.2011.11.079  0.343
2012 Chen C, Uludağ H, Wang Z, Rezansoff A, Jiang H. Macrophages inhibit migration, metabolic activity and osteogenic differentiation of human mesenchymal stem cells in vitro. Cells, Tissues, Organs. 195: 473-83. PMID 22156615 DOI: 10.1159/000330686  0.343
2012 Mostafa NZ, Fitzsimmons R, Major PW, Adesida A, Jomha N, Jiang H, Uludağ H. Osteogenic differentiation of human mesenchymal stem cells cultured with dexamethasone, vitamin D3, basic fibroblast growth factor, and bone morphogenetic protein-2. Connective Tissue Research. 53: 117-31. PMID 21966879 DOI: 10.3109/03008207.2011.611601  0.407
2012 Aliabadi HM, Uludag H. Abstract B32: Impact of Lipid-Substitution on Assembly and Delivery of siRNA by Cationic Polymers Clinical Cancer Research. 18: B32-B32. DOI: 10.1158/1078-0432.Mechres-B32  0.386
2012 Aliabadi HM, Uludag H. Abstract A65: Combinational siRNA silencing of MCL-1 and P-gp enhances the apoptotic response in Human Breast Cancer Cells Clinical Cancer Research. 18: A65-A65. DOI: 10.1158/1078-0432.Mechres-A65  0.317
2012 Falamarzian A, Xiong XB, Uludag H, Lavasanifar A. Polymeric micelles for siRNA delivery Journal of Drug Delivery Science and Technology. 22: 43-54. DOI: 10.1016/S1773-2247(12)50004-3  0.36
2011 Mostafa NZ, Uludağ H, Varkey M, Dederich DN, Doschak MR, El-Bialy TH. In vitro osteogenic induction of human gingival fibroblasts for bone regeneration. The Open Dentistry Journal. 5: 139-45. PMID 21915227 DOI: 10.2174/1874210601105010139  0.462
2011 Wang G, Babadağli ME, Uludağ H. Bisphosphonate-derivatized liposomes to control drug release from collagen/hydroxyapatite scaffolds. Molecular Pharmaceutics. 8: 1025-34. PMID 21557579 DOI: 10.1021/Mp200028W  0.365
2011 Zhi L, Chen C, Pang X, Uludag H, Jiang H. Synergistic effect of recombinant human bone morphogenic protein-7 and osteogenic differentiation medium on human bone-marrow-derived mesenchymal stem cells in vitro. International Orthopaedics. 35: 1889-95. PMID 21487672 DOI: 10.1007/S00264-011-1247-1  0.467
2011 Hsu CY, Hendzel M, Uludaǧ H. Improved transfection efficiency of an aliphatic lipid substituted 2 kDa polyethylenimine is attributed to enhanced nuclear association and uptake in rat bone marrow stromal cell. The Journal of Gene Medicine. 13: 46-59. PMID 21259408 DOI: 10.1002/jgm.1526  0.55
2011 Bahadur KC, Landry B, Aliabadi HM, Lavasanifar A, Uludağ H. Lipid substitution on low molecular weight (0.6-2.0 kDa) polyethylenimine leads to a higher zeta potential of plasmid DNA and enhances transgene expression. Acta Biomaterialia. 7: 2209-17. PMID 21256988 DOI: 10.1016/J.Actbio.2011.01.027  0.359
2011 Zhang D, Chu F, Yang Y, Xia L, Zeng D, Uludağ H, Zhang X, Qian Y, Jiang X. Orthodontic tooth movement in alveolar cleft repaired with a tissue engineering bone: an experimental study in dogs. Tissue Engineering. Part A. 17: 1313-25. PMID 21226625 DOI: 10.1089/Ten.Tea.2010.0490  0.463
2011 Remant Bahadur KC, Uludağ H. A comparative evaluation of disulfide-linked and hydrophobically-modified PEI for plasmid delivery. Journal of Biomaterials Science. Polymer Edition. 22: 873-92. PMID 20573316 DOI: 10.1163/092050610X496297  0.379
2010 Alshamsan A, Haddadi A, Hamdy S, Samuel J, El-Kadi AO, Uludağ H, Lavasanifar A. STAT3 silencing in dendritic cells by siRNA polyplexes encapsulated in PLGA nanoparticles for the modulation of anticancer immune response. Molecular Pharmaceutics. 7: 1643-54. PMID 20804176 DOI: 10.1021/Mp100067U  0.321
2010 Abbasi M, Lavasanifar A, Berthiaume LG, Weinfeld M, Uludağ H. Cationic polymer-mediated small interfering RNA delivery for P-glycoprotein down-regulation in tumor cells. Cancer. 116: 5544-54. PMID 20715163 DOI: 10.1002/Cncr.25321  0.316
2010 Taghavi CE, Lee KB, He W, Keorochana G, Murray SS, Brochmann EJ, Uludag H, Behnam K, Wang JC. Bone morphogenetic protein binding peptide mechanism and enhancement of osteogenic protein-1 induced bone healing. Spine. 35: 2049-56. PMID 20581758 DOI: 10.1097/Brs.0B013E3181Cc0220  0.479
2010 Xiong XB, Uludağ H, Lavasanifar A. Virus-mimetic polymeric micelles for targeted siRNA delivery. Biomaterials. 31: 5886-93. PMID 20427082 DOI: 10.1016/J.Biomaterials.2010.03.075  0.336
2010 Bhandari KH, Newa M, Uludag H, Doschak MR. Synthesis, characterization and in vitro evaluation of a bone targeting delivery system for salmon calcitonin. International Journal of Pharmaceutics. 394: 26-34. PMID 20412845 DOI: 10.1016/J.Ijpharm.2010.04.015  0.529
2010 Wang G, Kucharski C, Lin X, Uludağ H. Bisphosphonate-coated BSA nanoparticles lack bone targeting after systemic administration. Journal of Drug Targeting. 18: 611-26. PMID 20158316 DOI: 10.3109/10611861003622560  0.401
2010 Alshamsan A, Hamdy S, Samuel J, El-Kadi AO, Lavasanifar A, Uludağ H. The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine. Biomaterials. 31: 1420-8. PMID 19913908 DOI: 10.1016/J.Biomaterials.2009.11.003  0.326
2010 Wang S, Zhang Z, Xia L, Zhao J, Sun X, Zhang X, Ye D, Uludağ H, Jiang X. Systematic evaluation of a tissue-engineered bone for maxillary sinus augmentation in large animal canine model. Bone. 46: 91-100. PMID 19761881 DOI: 10.1016/J.Bone.2009.09.008  0.426
2010 Incani V, Lavasanifar A, Uludağ H. Lipid and hydrophobic modification of cationic carriers on route to superior gene vectors Soft Matter. 6: 2124. DOI: 10.1039/B916362J  0.364
2009 Incani V, Lin X, Lavasanifar A, Uludağ H. Relationship between the extent of lipid substitution on poly(L-lysine) and the DNA delivery efficiency. Acs Applied Materials & Interfaces. 1: 841-8. PMID 20356010 DOI: 10.1021/Am8002445  0.392
2009 Doschak MR, Kucharski CM, Wright JE, Zernicke RF, Uludağ H. Improved bone delivery of osteoprotegerin by bisphosphonate conjugation in a rat model of osteoarthritis. Molecular Pharmaceutics. 6: 634-40. PMID 19718808 DOI: 10.1021/Mp8002368  0.428
2009 Zhang S, Doschak MR, Uludağ H. Pharmacokinetics and bone formation by BMP-2 entrapped in polyethylenimine-coated albumin nanoparticles. Biomaterials. 30: 5143-55. PMID 19540582 DOI: 10.1016/J.Biomaterials.2009.05.060  0.388
2009 Clements BA, Hsu CY, Kucharski C, Lin X, Rose L, Uludağ H. Nonviral delivery of basic fibroblast growth factor gene to bone marrow stromal cells. Clinical Orthopaedics and Related Research. 467: 3129-37. PMID 19495899 DOI: 10.1007/S11999-009-0900-0  0.668
2009 Zhang S, Uludağ H. Nanoparticulate systems for growth factor delivery. Pharmaceutical Research. 26: 1561-80. PMID 19415467 DOI: 10.1007/S11095-009-9897-Z  0.357
2009 Alshamsan A, Haddadi A, Incani V, Samuel J, Lavasanifar A, Uludağ H. Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine. Molecular Pharmaceutics. 6: 121-33. PMID 19053537 DOI: 10.1021/Mp8000815  0.363
2008 Zhang S, Wang G, Lin X, Chatzinikolaidou M, Jennissen HP, Laub M, Uludağ H. Polyethylenimine-coated albumin nanoparticles for BMP-2 delivery. Biotechnology Progress. 24: 945-56. PMID 19194903 DOI: 10.1002/Btpr.12  0.353
2008 Wang G, Siggers K, Zhang S, Jiang H, Xu Z, Zernicke RF, Matyas J, Uludağ H. Preparation of BMP-2 containing bovine serum albumin (BSA) nanoparticles stabilized by polymer coating. Pharmaceutical Research. 25: 2896-909. PMID 18709447 DOI: 10.1007/S11095-008-9692-2  0.376
2008 Xiong XB, Mahmud A, Uludağ H, Lavasanifar A. Multifunctional polymeric micelles for enhanced intracellular delivery of doxorubicin to metastatic cancer cells. Pharmaceutical Research. 25: 2555-66. PMID 18636321 DOI: 10.1007/S11095-008-9673-5  0.333
2008 Abbasi M, Uludag H, Incani V, Hsu CY, Jeffery A. Further investigation of lipid-substituted poly(L-Lysine) polymers for transfection of human skin fibroblasts. Biomacromolecules. 9: 1618-30. PMID 18498191 DOI: 10.1021/bm800132n  0.5
2008 Wang G, Uludag H. Recent developments in nanoparticle-based drug delivery and targeting systems with emphasis on protein-based nanoparticles. Expert Opinion On Drug Delivery. 5: 499-515. PMID 18491978 DOI: 10.1517/17425247.5.5.499  0.303
2008 Hsu CY, Uludağ H. Effects of size and topology of DNA molecules on intracellular delivery with non-viral gene carriers. Bmc Biotechnology. 8: 23. PMID 18312664 DOI: 10.1186/1472-6750-8-23  0.515
2008 Zhang S, Wang G, Jennissen H, Chatzinikolaidou M, Uludag H. Bone morphogenetic protein-2 delivery systems based on polyethylenimine- coated albumin nanoparticles 8th World Biomaterials Congress 2008. 3: 1624.  0.322
2007 Clements BA, Incani V, Kucharski C, Lavasanifar A, Ritchie B, Uludağ H. A comparative evaluation of poly-L-lysine-palmitic acid and Lipofectamine 2000 for plasmid delivery to bone marrow stromal cells. Biomaterials. 28: 4693-704. PMID 17686514 DOI: 10.1016/J.Biomaterials.2007.07.023  0.456
2007 Zhang S, Wright JE, Ozber N, Uludağ H. The interaction of cationic polymers and their bisphosphonate derivatives with hydroxyapatite. Macromolecular Bioscience. 7: 656-70. PMID 17457941 DOI: 10.1002/Mabi.200600286  0.452
2007 Varkey M, Kucharski C, Doschak MR, Winn SR, Brochmann EJ, Murray S, Matyas JR, Zernicke RF, Uludag H. Osteogenic response of bone marrow stromal cells from normal and ovariectomized rats treated with a low dose of basic fibroblast growth factor. Tissue Engineering. 13: 809-17. PMID 17394387 DOI: 10.1089/Ten.2006.0348  0.451
2007 Incani V, Tunis E, Clements BA, Olson C, Kucharski C, Lavasanifar A, Uludag H. Palmitic acid substitution on cationic polymers for effective delivery of plasmid DNA to bone marrow stromal cells. Journal of Biomedical Materials Research. Part A. 81: 493-504. PMID 17340629 DOI: 10.1002/Jbm.A.31249  0.469
2007 Abbasi M, Uludag H, Incani V, Olson C, Lin X, Clements BA, Rutkowski D, Ghahary A, Weinfeld M. Palmitic acid-modified poly-L-lysine for non-viral delivery of plasmid DNA to skin fibroblasts. Biomacromolecules. 8: 1059-63. PMID 17335285 DOI: 10.1021/Bm060940X  0.331
2007 Zhang S, Gangal G, Uludağ H. 'Magic bullets' for bone diseases: progress in rational design of bone-seeking medicinal agents. Chemical Society Reviews. 36: 507-31. PMID 17325789 DOI: 10.1039/B512310K  0.489
2007 Xiong XB, Mahmud A, Uludağ H, Lavasanifar A. Conjugation of arginine-glycine-aspartic acid peptides to poly(ethylene oxide)-b-poly(epsilon-caprolactone) micelles for enhanced intracellular drug delivery to metastatic tumor cells. Biomacromolecules. 8: 874-84. PMID 17315946 DOI: 10.1021/Bm060967G  0.327
2007 Farrell LL, Pepin J, Kucharski C, Lin X, Xu Z, Uludag H. A comparison of the effectiveness of cationic polymers poly-L-lysine (PLL) and polyethylenimine (PEI) for non-viral delivery of plasmid DNA to bone marrow stromal cells (BMSC). European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 65: 388-97. PMID 17240127 DOI: 10.1016/J.Ejpb.2006.11.026  0.439
2006 Clements BA, Bai J, Kucharski C, Farrell LL, Lavasanifar A, Ritchie B, Ghahary A, Uludag H. RGD conjugation to polyethyleneimine does not improve DNA delivery to bone marrow stromal cells. Biomacromolecules. 7: 1481-8. PMID 16677029 DOI: 10.1021/Bm060073W  0.473
2006 Wright JE, Gittens SA, Bansal G, Kitov PI, Sindrey D, Kucharski C, Uludağ H. A comparison of mineral affinity of bisphosphonate-protein conjugates constructed with disulfide and thioether linkages. Biomaterials. 27: 769-84. PMID 16055182 DOI: 10.1016/J.Biomaterials.2005.06.012  0.763
2006 Uludag H, Incani V, Tunis E, Acan B, Olsen C, Kucharski C, Ghahary A, Lavasanifar A. Potential of lipid-modified polycations to transfer plasmid DNA into bone marrow stromal cells (BMSC) Journal of Biomechanics. 39: S259. DOI: 10.1016/S0021-9290(06)83989-8  0.34
2006 Hsu CY, Kucharski C, Uludag H. 530. The Effects DNA Molecular Weights and Conformations on Cell Uptake and the Binding Interaction with Cationic Polymers Used for Non-Viral Gene Delivery Molecular Therapy. 13: S203-S204. DOI: 10.1016/J.Ymthe.2006.08.601  0.324
2006 Clements BA, Incani V, Kucharski C, Lavasanifar A, Uludag H. 200. A Novel Non-Viral Polymer for Plasmid Delivery to Bone Marrow Stromal Cells (BMSC) Molecular Therapy. 13: S78. DOI: 10.1016/J.Ymthe.2006.08.224  0.504
2006 Jiang X, Bai J, Gittens SA, Uludaǧ H. Growth of bone marrow stromal cells on RGD-grafted thermoreversible (NiPAM) polymers Materialwissenschaft Und Werkstofftechnik. 37: 462-468. DOI: 10.1002/Mawe.200600020  0.766
2005 Gittens SA, Bansal G, Kucharski C, Borden M, Uludag H. Imparting mineral affinity to fetuin by bisphosphonate conjugation: a comparison of three bisphosphonate conjugation schemes. Molecular Pharmaceutics. 2: 392-406. PMID 16196492 DOI: 10.1021/Mp050017U  0.786
2005 Zhang S, Wright JE, Bansal G, Cho P, Uludag H. Cleavage of disulfide-linked fetuin-bisphosphonate conjugates with three physiological thiols. Biomacromolecules. 6: 2800-8. PMID 16153121 DOI: 10.1021/Bm050273S  0.511
2005 Bansal G, Wright JE, Zhang S, Zernicke RF, Uludag H. Imparting mineral affinity to proteins with thiol-labile disulfide linkages. Journal of Biomedical Materials Research. Part A. 74: 618-28. PMID 16037953 DOI: 10.1002/Jbm.A.30334  0.413
2005 Smith E, Yang J, McGann L, Sebald W, Uludag H. RGD-grafted thermoreversible polymers to facilitate attachment of BMP-2 responsive C2C12 cells. Biomaterials. 26: 7329-38. PMID 16019067 DOI: 10.1016/J.Biomaterials.2005.05.060  0.389
2005 Bansal G, Wright JE, Kucharski C, Uludağ H. A dendritic tetra(bisphosphonic acid) for improved targeting of proteins to bone. Angewandte Chemie (International Ed. in English). 44: 3710-4. PMID 15880536 DOI: 10.1002/Anie.200500350  0.473
2005 Gittens SA, Bansal G, Zernicke RF, Uludağ H. Designing proteins for bone targeting. Advanced Drug Delivery Reviews. 57: 1011-36. PMID 15876401 DOI: 10.1016/J.Addr.2004.12.015  0.801
2005 Haque T, Uludag H, Zernicke RF, Winn SR, Sebald W. Bone marrow cells from normal and ovariectomized rats respond differently to basic fibroblast growth factor and bone morphogenetic protein 2 treatment in vitro. Tissue Engineering. 11: 634-44. PMID 15869440 DOI: 10.1089/Ten.2005.11.634  0.426
2004 Varkey M, Gittens SA, Uludag H. Growth factor delivery for bone tissue repair: an update. Expert Opinion On Drug Delivery. 1: 19-36. PMID 16296718 DOI: 10.1517/17425247.1.1.19  0.801
2004 Wright JE, Zhao L, Choi P, Uludag H. Simulating hydroxyapatite binding of bone-seeking bisphosphonates. Advances in Experimental Medicine and Biology. 553: 139-48. PMID 15503453 DOI: 10.1007/978-0-306-48584-8_11  0.487
2004 Norrie B, Jalil A, Lakey JR, Rajotte RV, Uludag H. In-situ crosslinking thermoreversible polymers for cell entrapment. Advances in Experimental Medicine and Biology. 553: 19-28. PMID 15503444 DOI: 10.1007/978-0-306-48584-8_2  0.327
2004 Bansal G, Gittens SA, Uludağ H. A di(bisphosphonic acid) for protein coupling and targeting to bone. Journal of Pharmaceutical Sciences. 93: 2788-99. PMID 15368528 DOI: 10.1002/Jps.20186  0.801
2004 Gittens SA, Bagnall K, Matyas JR, Löbenberg R, Uludag H. Imparting bone mineral affinity to osteogenic proteins through heparin-bisphosphonate conjugates. Journal of Controlled Release : Official Journal of the Controlled Release Society. 98: 255-68. PMID 15262417 DOI: 10.1016/J.Jconrel.2004.05.001  0.775
2004 Gittens SA, Wohl GR, Zernicke RF, Matyas JR, Morley P, Uludag H. Systemic bone formation with weekly PTH administration in ovariectomized rats. Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society For Pharmaceutical Sciences, SociéTé Canadienne Des Sciences Pharmaceutiques. 7: 27-37. PMID 15144732  0.762
2004 Gittens SA, Kitov PI, Matyas JR, Löbenberg R, Uludağ H. Impact of tether length on bone mineral affinity of protein-bisphosphonate conjugates. Pharmaceutical Research. 21: 608-16. PMID 15139517 DOI: 10.1023/B:Pham.0000022407.05163.01  0.79
2004 Bai J, Açan B, Ghahary A, Ritchie B, Somayaji V, Uludağ H. Poly(ethyleneimine)/arginine-glycine-aspartic acid conjugates prepared withN-succinimidyl 3-(2-pyridyldithio)propionate: An investigation of peptide coupling and conjugate stability Journal of Polymer Science Part a: Polymer Chemistry. 42: 6143-6156. DOI: 10.1002/Pola.20472  0.318
2004 Jiang X, Bai J, Uludag H, Zhang Z. Effect of RGD-grafted thermoreversible polymers on bone marrow stromal cell growth and alkaline phosphatase activity Transactions - 7th World Biomaterials Congress. 1320.  0.336
2004 Haque T, Uludag H, Zernicke RF, Winn SR. Osteogenic response of bone marrow stromal cells from normal and ovariectomized rats to bFGF and BMP-2 Transactions - 7th World Biomaterials Congress. 901.  0.32
2004 Gittens SA, Matyas JR, Loebenberg R, Zernicke RF, Uludag H. Enhancing glycoprotein affinity to hydroxyapatite bone substitutes in vitro and in vivo Transactions - 7th World Biomaterials Congress. 1539.  0.789
2003 Gittens SA, Matyas JR, Zernicke RF, Uludağ H. Imparting bone affinity to glycoproteins through the conjugation of bisphosphonates. Pharmaceutical Research. 20: 978-87. PMID 12880282 DOI: 10.1023/A:1024445903306  0.794
2003 Smith E, Bai J, Oxenford C, Yang J, Somayaji R, Uludag H. Conjugation of arginine-glycine-aspartic acid peptides to thermoreversible N-isopropylacrylamide polymers Journal of Polymer Science, Part a: Polymer Chemistry. 41: 3989-4000. DOI: 10.1002/Pola.10965  0.315
2002 Uludag H. Bisphosphonates as a foundation of drug delivery to bone. Current Pharmaceutical Design. 8: 1929-44. PMID 12171528 DOI: 10.2174/1381612023393585  0.474
2002 Gao TJ, Kousinioris NA, Wozney JM, Winn S, Uludag H. Synthetic thermoreversible polymers are compatible with osteoinductive activity of recombinant human bone morphogenetic protein 2. Tissue Engineering. 8: 429-40. PMID 12167229 DOI: 10.1089/107632702760184691  0.423
2002 Uludag H, Yang J. Targeting systemically administered proteins to bone by bisphosphonate conjugation. Biotechnology Progress. 18: 604-11. PMID 12052079 DOI: 10.1021/Bp0200447  0.537
2001 Gittens SA, Uludag H. Growth factor delivery for bone tissue engineering. Journal of Drug Targeting. 9: 407-29. PMID 11822814 DOI: 10.3109/10611860108998776  0.787
2001 Gao T, Uludag H. Effect of molecular weight of thermoreversible polymer on in vivo retention of rhBMP-2 Journal of Biomedical Materials Research. 57: 92-100. PMID 11416854 DOI: 10.1002/1097-4636(200110)57:1<92::Aid-Jbm1146>3.0.Co;2-1  0.331
2001 Uludag H, Norrie B, Kousinioris N, Gao T. Engineering temperature-sensitive poly(N-Isopropylacrylamide) polymers as carriers of therapeutic proteins Biotechnology and Bioengineering. 73: 510-521. PMID 11344456 DOI: 10.1002/Bit.1086  0.4
2001 Uludag H, Gao T, Porter TJ, Friess W, Wozney JM. Delivery systems for BMPs: Factors contributing to protein retention at an application site Journal of Bone and Joint Surgery - Series A. 83. DOI: 10.2106/00004623-200100002-00007  0.499
2001 Gao T, Kousinioris N, Winn SR, Wozney JM, Uludag H. Enhanced retention of rhBMP-2 in vivo by thermoreversible polymers Materialwissenschaft Und Werkstofftechnik. 32: 953-961. DOI: 10.1002/1521-4052(200112)32:12<953::Aid-Mawe953>3.0.Co;2-1  0.378
2000 Uludag H, Gao T, Wohl GR, Kantoci D, Zernicke RF. Bone affinity of a bisphosphonate-conjugated protein in vivo. Biotechnology Progress. 16: 1115-8. PMID 11101342 DOI: 10.1021/Bp000066Y  0.515
2000 Uludag H, Kousinioris N, Gao T, Kantoci D. Bisphosphonate conjugation to proteins as a means to impart bone affinity Biotechnology Progress. 16: 258-267. PMID 10753453 DOI: 10.1021/Bp990154M  0.533
2000 Uludag H, D'Augusta D, Golden J, Li J, Timony G, Riedel R, Wozney JM. Implantation of recombinant human bone morphogenetic proteins with biomaterial carriers: A correlation between protein pharmacokinetics and osteoinduction in the rat ectopic model Journal of Biomedical Materials Research. 50: 227-238. PMID 10679688 DOI: 10.1002/(Sici)1097-4636(200005)50:2<227::Aid-Jbm18>3.0.Co;2-2  0.405
2000 Uludag H, Wong M, Man J. Reactivity of temperature-sensitive, protein-conjugating polymers prepared by a photopolymerization process Journal of Applied Polymer Science. 75: 583-592. DOI: 10.1002/(Sici)1097-4628(20000124)75:4<583::Aid-App15>3.0.Co;2-L  0.325
1999 Uludag H, Golden J, Palmer R, Wozney JM. Biotinated bone morphogenetic protein-2: In vivo and in vitro activity Biotechnology and Bioengineering. 65: 668-672. PMID 10550773 DOI: 10.1002/(Sici)1097-0290(19991220)65:6<668::Aid-Bit7>3.0.Co;2-8  0.499
1999 Winn SR, Uludag H, Hollinger JO. Carrier systems for bone morphogenetic proteins Clinical Orthopaedics and Related Research. PMID 10546639 DOI: 10.1097/00003086-199910001-00010  0.52
1999 Friess W, Uludag H, Foskett S, Biron R, Sargeant C. Characterization of absorbable collagen sponges as rhBMP-2 carriers International Journal of Pharmaceutics. 187: 91-99. PMID 10502616 DOI: 10.1016/S0378-5173(99)00174-X  0.436
1999 Winn SR, Randolph G, Uludag H, Wong SC, Hair GA, Hollinger JO. Establishing an immortalized human osteoprecursor cell line: OPC1 Journal of Bone and Mineral Research. 14: 1721-1733. PMID 10491220 DOI: 10.1359/Jbmr.1999.14.10.1721  0.411
1999 Friess W, Uludag H, Foskett S, Biron R. Bone regeneration with recombinant human bone morphogenetic protein-2 (rhBMP-2) using absorbable collagen sponges (ACS): Influence of processing on ACS characteristics and formulation Pharmaceutical Development and Technology. 4: 387-396. PMID 10434284 DOI: 10.1081/Pdt-100101374  0.416
1999 Friess W, Uludag H, Foskett S, Biron R, Sargeant C. Characterization of absorbable collagen sponges as recombinant human bone morphogenetic protein-2 carriers International Journal of Pharmaceutics. 185: 51-60. PMID 10425365 DOI: 10.1016/S0378-5173(99)00128-3  0.461
1999 Uludag H, Friess W, Williams D, Porter T, Timony G, D'Augusta D, Blake C, Palmer R, Biron B, Wozney J. rhBMP-collagen sponges as osteoinductive devices: effects of in vitro sponge characteristics and protein pI on in vivo rhBMP pharmacokinetics. Annals of the New York Academy of Sciences. 875: 369-78. PMID 10415583 DOI: 10.1111/J.1749-6632.1999.Tb08519.X  0.404
1999 Uludag H, D'Augusta D, Palmer R, Timony G, Wozney J. Characterization of rhBMP-2 pharmacokinetics implanted with biomaterial carriers in the rat ectopic model Journal of Biomedical Materials Research. 46: 193-202. PMID 10379997 DOI: 10.1002/(Sici)1097-4636(199908)46:2<193::Aid-Jbm8>3.0.Co;2-1  0.399
1998 Winn SR, Uludag H, Hollinger JO. Sustained release emphasizing recombinant human bone morphogenetic protein-2 Advanced Drug Delivery Reviews. 31: 303-318. DOI: 10.1016/S0169-409X(97)00126-9  0.5
1998 Uludag H. Osteoinductive alternatives and bone substitutes Current Opinion in Orthopaedics. 9: 31-37.  0.404
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