Robert M. Sears - Publications

Affiliations: 
Yale University, New Haven, CT 

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sears RM, Andrade EC, Samels SB, Laughlin LC, Moloney DM, Wilson DA, Alwood MR, Moscarello JM, Cain CK. Devaluation of response-produced safety signals reveals circuits for goal-directed versus habitual avoidance in dorsal striatum. Biorxiv : the Preprint Server For Biology. PMID 38370659 DOI: 10.1101/2024.02.07.579321  0.783
2021 Smiley JF, Bleiwas C, Canals-Baker S, Williams SZ, Sears R, Teixeira CM, Wilson DA, Saito M. Neonatal ethanol causes profound reduction of cholinergic cell number in the basal forebrain of adult animals. Alcohol (Fayetteville, N.Y.). PMID 34464696 DOI: 10.1016/j.alcohol.2021.08.005  0.546
2020 Laughlin LC, Moloney DM, Samels SB, Sears RM, Cain CK. Reducing shock imminence eliminates poor avoidance in rats. Learning & Memory (Cold Spring Harbor, N.Y.). 27: 270-274. PMID 32540916 DOI: 10.1101/lm.051557.120  0.648
2019 Ostroff LE, Santini E, Sears R, Deane Z, Kanadia RN, LeDoux JE, Lhakhang T, Tsirigos A, Heguy A, Klann E. Axon TRAP reveals learning-associated alterations in cortical axonal mRNAs in the lateral amgydala. Elife. 8. PMID 31825308 DOI: 10.7554/Elife.51607  0.765
2019 Gu Y, Piper WT, Branigan LA, Vazey EM, Aston-Jones G, Lin L, LeDoux JE, Sears RM. A brainstem-central amygdala circuit underlies defensive responses to learned threats. Molecular Psychiatry. PMID 31758092 DOI: 10.1038/S41380-019-0599-6  0.724
2018 Krypotos AM, Moscarello JM, Sears RM, LeDoux JE, Galatzer-Levy I. A principled method to identify individual differences and behavioral shifts in signaled active avoidance. Learning & Memory (Cold Spring Harbor, N.Y.). 25: 564-568. PMID 30322888 DOI: 10.1101/Lm.047399.118  0.744
2017 Campese VD, Soroeta JM, Vazey EM, Aston-Jones G, LeDoux JE, Sears RM. Noradrenergic Regulation of Central Amygdala in Aversive Pavlovian-to-Instrumental Transfer. Eneuro. 4. PMID 29071299 DOI: 10.1523/ENEURO.0224-17.2017  0.688
2017 Díaz-Mataix L, Piper WT, Schiff HC, Roberts CH, Campese VD, Sears RM, LeDoux JE. Characterization of the amplificatory effect of norepinephrine in the acquisition of Pavlovian threat associations. Learning & Memory (Cold Spring Harbor, N.Y.). 24: 432-439. PMID 28814469 DOI: 10.1101/Lm.044412.116  0.774
2017 Wigestrand MB, Schiff HC, Fyhn M, LeDoux JE, Sears RM. Primary auditory cortex regulates threat memory specificity. Learning & Memory (Cold Spring Harbor, N.Y.). 24: 55-58. PMID 27980076 DOI: 10.1101/Lm.044362.116  0.77
2016 Schiff HC, Johansen JP, Hou M, Bush DE, Smith EK, Klein JE, LeDoux JE, Sears RM. β-Adrenergic Receptors Regulate the Acquisition and Consolidation Phases of Aversive Memory Formation through Distinct, Temporally-Regulated Signaling Pathways. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27762270 DOI: 10.1038/Npp.2016.238  0.796
2016 LeDoux JE, Moscarello J, Sears R, Campese V. The birth, death and resurrection of avoidance: a reconceptualization of a troubled paradigm. Molecular Psychiatry. PMID 27752080 DOI: 10.1038/Mp.2016.166  0.786
2016 Baslow MH, Cain CK, Sears R, Wilson DA, Bachman A, Gerum S, Guilfoyle DN. Stimulation-induced transient changes in neuronal activity, blood flow and N-acetylaspartate content in rat prefrontal cortex: a chemogenetic fMRS-BOLD study. Nmr in Biomedicine. PMID 27696530 DOI: 10.1002/nbm.3629  0.718
2015 Campese VD, Sears RM, Moscarello JM, Diaz-Mataix L, Cain CK, LeDoux JE. The Neural Foundations of Reaction and Action in Aversive Motivation. Current Topics in Behavioral Neurosciences. PMID 26643998 DOI: 10.1007/7854_2015_401  0.773
2015 Anastasio NC, Stutz SJ, Fink LH, Swinford-Jackson SE, Sears RM, DiLeone RJ, Rice KC, Moeller FG, Cunningham KA. Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity. Acs Chemical Neuroscience. PMID 26120876 DOI: 10.1021/Acschemneuro.5B00094  0.587
2015 Ramirez F, Moscarello JM, LeDoux JE, Sears RM. Active avoidance requires a serial basal amygdala to nucleus accumbens shell circuit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3470-7. PMID 25716846 DOI: 10.1523/Jneurosci.1331-14.2015  0.787
2015 Neelakantan H, Stutz SJ, Bubar MJ, Sears RM, DiLeone RJ, Cunningham KA. Serotonin 5-HT 2C receptors in the ventral subiculum regulate cocaine-evoked hyperactivity in rats Drug and Alcohol Dependence. 156: e161-e162. DOI: 10.1016/J.Drugalcdep.2015.07.440  0.603
2014 Sears RM, Schiff HC, LeDoux JE. Molecular mechanisms of threat learning in the lateral nucleus of the amygdala. Progress in Molecular Biology and Translational Science. 122: 263-304. PMID 24484705 DOI: 10.1016/B978-0-12-420170-5.00010-6  0.792
2014 Anastasio NC, Stutz SJ, Fox RG, Sears RM, Emeson RB, DiLeone RJ, O'Neil RT, Fink LH, Li D, Green TA, Moeller FG, Cunningham KA. Functional status of the serotonin 5-HT2C receptor (5-HT2CR) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 370-82. PMID 23939424 DOI: 10.1038/Npp.2013.199  0.63
2014 Anastasio NC, Stutz S, Fink L, Fox R, Sears R, Green T, DiLeone R, Moeller F, Cunningham K. Maladaptive cortical serotonin (5-ht) 5-ht2a:5-ht2c receptor balance generates aberrant impulsivity and elevated cocaine cue reactivity Drug and Alcohol Dependence. 140: e4-e5. DOI: 10.1016/J.Drugalcdep.2014.02.034  0.574
2013 Sears RM, Fink AE, Wigestrand MB, Farb CR, de Lecea L, Ledoux JE. Orexin/hypocretin system modulates amygdala-dependent threat learning through the locus coeruleus. Proceedings of the National Academy of Sciences of the United States of America. 110: 20260-5. PMID 24277819 DOI: 10.1073/Pnas.1320325110  0.558
2013 Martinez RC, Gupta N, Lázaro-Muñoz G, Sears RM, Kim S, Moscarello JM, LeDoux JE, Cain CK. Active vs. reactive threat responding is associated with differential c-Fos expression in specific regions of amygdala and prefrontal cortex. Learning & Memory (Cold Spring Harbor, N.Y.). 20: 446-52. PMID 23869027 DOI: 10.1101/Lm.031047.113  0.789
2011 Trinko R, Gan G, Gao XB, Sears RM, Guarnieri DJ, DiLeone RJ. Erk1/2 mediates leptin receptor signaling in the ventral tegmental area. Plos One. 6: e27180. PMID 22076135 DOI: 10.1371/Journal.Pone.0027180  0.763
2011 Mul JD, la Fleur SE, Toonen PW, Afrasiab-Middelman A, Binnekade R, Schetters D, Verheij MM, Sears RM, Homberg JR, Schoffelmeer AN, Adan RA, DiLeone RJ, De Vries TJ, Cuppen E. Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat. Plos One. 6: e19600. PMID 21573180 DOI: 10.1371/journal.pone.0019600  0.65
2010 Sears RM, Liu RJ, Narayanan NS, Sharf R, Yeckel MF, Laubach M, Aghajanian GK, DiLeone RJ. Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8263-73. PMID 20554878 DOI: 10.1523/Jneurosci.5858-09.2010  0.786
2007 Trinko R, Sears RM, Guarnieri DJ, DiLeone RJ. Neural mechanisms underlying obesity and drug addiction. Physiology & Behavior. 91: 499-505. PMID 17292426 DOI: 10.1016/J.Physbeh.2007.01.001  0.734
2006 Hommel JD, Trinko R, Sears RM, Georgescu D, Liu ZW, Gao XB, Thurmon JJ, Marinelli M, DiLeone RJ. Leptin receptor signaling in midbrain dopamine neurons regulates feeding. Neuron. 51: 801-10. PMID 16982424 DOI: 10.1016/J.Neuron.2006.08.023  0.746
2005 Georgescu D, Sears RM, Hommel JD, Barrot M, Bolaños CA, Marsh DJ, Bednarek MA, Bibb JA, Maratos-Flier E, Nestler EJ, DiLeone RJ. The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2933-40. PMID 15772353 DOI: 10.1523/Jneurosci.1714-04.2005  0.796
2003 Hommel JD, Sears RM, Georgescu D, Simmons DL, DiLeone RJ. Local gene knockdown in the brain using viral-mediated RNA interference. Nature Medicine. 9: 1539-44. PMID 14634645 DOI: 10.1038/Nm964  0.752
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