Sylvia B. Smith - Publications

Affiliations: 
Medical College of Georgia, Augusta, GA, United States 
Area:
Cell Biology, Biochemistry

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang J, Saul A, Smith SB. Activation of Sigma 1 Receptor Extends Survival of Cones and Improves Visual Acuity in a Murine Model of Retinitis Pigmentosa. Investigative Ophthalmology & Visual Science. 60: 4397-4407. PMID 31639826 DOI: 10.1167/iovs.19-27709  0.32
2019 Porter MR, Xiao H, Wang J, Smith SB, Topczewski JJ. 3-Amino-chromanes and Tetrahydroquinolines as Selective 5-HT, 5-HT, or σ Receptor Ligands. Acs Medicinal Chemistry Letters. 10: 1436-1442. PMID 31620230 DOI: 10.1021/acsmedchemlett.9b00225  0.32
2019 Navneet S, Zhao J, Wang J, Mysona B, Barwick S, Ammal Kaidery N, Saul A, Kaddour-Djebbar I, Bollag WB, Thomas B, Bollinger KE, Smith SB. Hyperhomocysteinemia-induced death of retinal ganglion cells: The role of Müller glial cells and NRF2. Redox Biology. 24: 101199. PMID 31026769 DOI: 10.1016/j.redox.2019.101199  0.64
2018 Navneet S, Cui X, Zhao J, Wang J, Ammal Kaidery N, Thomas B, Bollinger KE, Yoon Y, Smith SB. Excess homocysteine upregulates the NRF2-antioxidant pathway in retinal Müller glial cells. Experimental Eye Research. PMID 29608906 DOI: 10.1016/j.exer.2018.03.022  0.32
2018 Chaudhary K, Promsote W, Ananth S, Veeranan-Karmegam R, Tawfik A, Arjunan P, Martin P, Smith SB, Thangaraju M, Kisselev O, Ganapathy V, Gnana-Prakasam JP. Iron Overload Accelerates the Progression of Diabetic Retinopathy in Association with Increased Retinal Renin Expression. Scientific Reports. 8: 3025. PMID 29445185 DOI: 10.1038/s41598-018-21276-2  0.52
2017 Zhao J, Mysona BA, Wang J, Gonsalvez GB, Smith SB, Bollinger KE. Sigma 1 receptor regulates ERK activation and promotes survival of optic nerve head astrocytes. Plos One. 12: e0184421. PMID 28898265 DOI: 10.1371/journal.pone.0184421  0.32
2017 Wang J, Saul A, Cui X, Roon P, Smith SB. Absence of Sigma 1 Receptor Accelerates Photoreceptor Cell Death in a Murine Model of Retinitis Pigmentosa. Investigative Ophthalmology & Visual Science. 58: 4545-4558. PMID 28877319 DOI: 10.1167/iovs.17-21947  0.64
2017 Zhu S, Luo H, Liu H, Ha Y, Mays ER, Lawrence RE, Winkelmann E, Barrett AD, Smith SB, Wang M, Wang T, Zhang W. p38MAPK plays a critical role in induction of a pro-inflammatory phenotype of retinal Müller cells following Zika virus infection. Antiviral Research. PMID 28739278 DOI: 10.1016/j.antiviral.2017.07.012  0.4
2017 Cui X, Navneet S, Wang J, Roon P, Chen W, Xian M, Smith SB. Analysis of MTHFR, CBS, Glutathione, Taurine, and Hydrogen Sulfide Levels in Retinas of Hyperhomocysteinemic Mice. Investigative Ophthalmology & Visual Science. 58: 1954-1963. PMID 28384716 DOI: 10.1167/iovs.16-21247  0.64
2017 Wang J, Cui X, Roon P, Saul A, Smith SB. The Role of Sigma1R in Mammalian Retina. Advances in Experimental Medicine and Biology. 964: 267-284. PMID 28315277 DOI: 10.1007/978-3-319-50174-1_18  0.64
2016 Promsote W, Powell FL, Veean S, Thounaojam M, Markand S, Saul A, Gutsaeva D, Bartoli M, Smith SB, Ganapathy V, Martin P. Oral monomethylfumarate therapy ameliorates retinopathy in a humanized mouse model of sickle cell disease. Antioxidants & Redox Signaling. PMID 27393735 DOI: 10.1089/ars.2016.6638  0.52
2016 Wang J, Saul A, Roon P, Smith SB. Activation of the molecular chaperone, sigma 1 receptor, preserves cone function in a murine model of inherited retinal degeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 27298364 DOI: 10.1073/pnas.1521749113  0.64
2016 Wang J, Cui X, Roon P, Smith SB. Role of Sigma 1 Receptor in Retinal Degeneration of the Ins2Akita/+ Murine Model of Diabetic Retinopathy. Investigative Ophthalmology & Visual Science. 57: 2770-2781. PMID 27206247 DOI: 10.1167/iovs.15-18995  0.64
2016 Ibrahim AS, Mander S, Hussein KA, Elsherbiny NM, Smith SB, Al-Shabrawey M, Tawfik A. Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age-related macular degeneration. Oncotarget. PMID 26885895 DOI: 10.18632/oncotarget.7384  0.52
2016 Zhao J, Mysona BA, Qureshi A, Kim L, Fields T, Gonsalvez GB, Smith SB, Bollinger KE. (+)-Pentazocine Reduces NMDA-Induced Murine Retinal Ganglion Cell Death Through a σR1-Dependent Mechanism. Investigative Ophthalmology & Visual Science. 57: 453-61. PMID 26868747 DOI: 10.1167/iovs.15-18565  0.52
2015 Markand S, Saul A, Tawfik A, Cui X, Rozen R, Smith SB. Mthfr as a modifier of the retinal phenotype of Crb1(rd8/rd8) mice. Experimental Eye Research. PMID 26646559 DOI: 10.1016/j.exer.2015.11.013  0.52
2015 Shanmugam AK, Mysona BA, Wang J, Zhao J, Tawfik A, Sanders A, Markand S, Zorrilla E, Ganapathy V, Bollinger KE, Smith SB. Progesterone Receptor Membrane Component 1 (PGRMC1) Expression in Murine Retina. Current Eye Research. 1-8. PMID 26642738 DOI: 10.3109/02713683.2015.1085579  0.52
2015 Wang J, Shanmugam A, Markand S, Zorrilla E, Ganapathy V, Smith SB. Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchanger. Free Radical Biology & Medicine. 86: 25-36. PMID 25920363 DOI: 10.1016/j.freeradbiomed.2015.04.009  0.52
2015 Markand S, Saul A, Roon P, Prasad P, Martin P, Rozen R, Ganapathy V, Smith SB. Retinal Ganglion Cell Loss and Mild Vasculopathy in Methylene Tetrahydrofolate Reductase (Mthfr)-Deficient Mice: A Model of Mild Hyperhomocysteinemia. Investigative Ophthalmology & Visual Science. 56: 2684-95. PMID 25766590 DOI: 10.1167/iovs.14-16190  0.52
2015 Ibrahim AS, Elshafey S, Sellak H, Hussein KA, El-Sherbiny M, Abdelsaid M, Rizk N, Beasley S, Tawfik AM, Smith SB, Al-Shabrawey M. A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase. Journal of Lipid Research. 56: 599-611. PMID 25598081 DOI: 10.1194/jlr.M056069  0.52
2015 Ibrahim AS, Tawfik AM, Hussein KA, Elshafey S, Markand S, Rizk N, Duh EJ, Smith SB, Al-Shabrawey M. Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids. Biochimica Et Biophysica Acta. 1851: 290-8. PMID 25562624 DOI: 10.1016/j.bbalip.2014.12.017  0.52
2015 Peng J, Li X, Zhang D, Chen JK, Su Y, Smith SB, Dong Z. Hyperglycemia, p53, and mitochondrial pathway of apoptosis are involved in the susceptibility of diabetic models to ischemic acute kidney injury. Kidney International. 87: 137-50. PMID 24963915 DOI: 10.1038/ki.2014.226  0.52
2014 Shanmugam A, Wang J, Markand S, Perry RL, Tawfik A, Zorrilla E, Ganapathy V, Smith SB. Sigma receptor 1 activation attenuates release of inflammatory cytokines MIP1γ, MIP2, MIP3α, and IL12 (p40/p70) by retinal Müller glial cells. Journal of Neurochemistry. PMID 25439327 DOI: 10.1111/jnc.13002  0.52
2014 Mo J, Marshall B, Covar J, Zhang NY, Smith SB, Atherton SS, Zhang M. Role of Bax in death of uninfected retinal cells during murine cytomegalovirus retinitis. Investigative Ophthalmology & Visual Science. 55: 7137-46. PMID 25298417 DOI: 10.1167/iovs.14-15404  0.52
2014 Tawfik A, Markand S, Al-Shabrawey M, Mayo JN, Reynolds J, Bearden SE, Ganapathy V, Smith SB. Alterations of retinal vasculature in cystathionine-β-synthase heterozygous mice: a model of mild to moderate hyperhomocysteinemia. The American Journal of Pathology. 184: 2573-85. PMID 25016930 DOI: 10.1016/j.ajpath.2014.05.018  0.52
2014 Frederick NM, Bertho J, Patel KK, Petr GT, Bakradze E, Smith SB, Rosenberg PA. Dysregulation of system xc(-) expression induced by mutant huntingtin in a striatal neuronal cell line and in R6/2 mice. Neurochemistry International. 76: 59-69. PMID 25004085 DOI: 10.1016/j.neuint.2014.06.017  0.52
2014 Promsote W, Makala L, Li B, Smith SB, Singh N, Ganapathy V, Pace BS, Martin PM. Monomethylfumarate induces γ-globin expression and fetal hemoglobin production in cultured human retinal pigment epithelial (RPE) and erythroid cells, and in intact retina. Investigative Ophthalmology & Visual Science. 55: 5382-93. PMID 24825111 DOI: 10.1167/iovs.14-14179  0.52
2014 Tawfik A, Gnana-Prakasam JP, Smith SB, Ganapathy V. Deletion of hemojuvelin, an iron-regulatory protein, in mice results in abnormal angiogenesis and vasculogenesis in retina along with reactive gliosis. Investigative Ophthalmology & Visual Science. 55: 3616-25. PMID 24812553 DOI: 10.1167/iovs.13-13677  0.52
2014 Zhao J, Ha Y, Liou GI, Gonsalvez GB, Smith SB, Bollinger KE. Sigma receptor ligand, (+)-pentazocine, suppresses inflammatory responses of retinal microglia. Investigative Ophthalmology & Visual Science. 55: 3375-84. PMID 24812552 DOI: 10.1167/iovs.13-12823  0.52
2014 Gnana-Prakasam JP, Baldowski RB, Ananth S, Martin PM, Smith SB, Ganapathy V. Retinal expression of the serine protease matriptase-2 (Tmprss6) and its role in retinal iron homeostasis. Molecular Vision. 20: 561-74. PMID 24791141  0.52
2014 Ha Y, Shanmugam AK, Markand S, Zorrilla E, Ganapathy V, Smith SB. Sigma receptor 1 modulates ER stress and Bcl2 in murine retina. Cell and Tissue Research. 356: 15-27. PMID 24469320 DOI: 10.1007/s00441-013-1774-8  0.52
2014 Ananth S, Gnana-Prakasam JP, Bhutia YD, Veeranan-Karmegam R, Martin PM, Smith SB, Ganapathy V. Regulation of the cholesterol efflux transporters ABCA1 and ABCG1 in retina in hemochromatosis and by the endogenous siderophore 2,5-dihydroxybenzoic acid. Biochimica Et Biophysica Acta. 1842: 603-12. PMID 24462739 DOI: 10.1016/j.bbadis.2014.01.010  0.52
2013 Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Srinivas SR, Babu E, Hawthorn L, Schoenlein PV, Boettger T, Smith SB, Prasad PD, Ganapathy V, Thangaraju M. Molecular mechanism of SLC5A8 inactivation in breast cancer. Molecular and Cellular Biology. 33: 3920-35. PMID 23918800 DOI: 10.1128/MCB.01702-12  0.52
2013 Markand S, Tawfik A, Ha Y, Gnana-Prakasam J, Sonne S, Ganapathy V, Sen N, Xian M, Smith SB. Cystathionine beta synthase expression in mouse retina. Current Eye Research. 38: 597-604. PMID 23470016 DOI: 10.3109/02713683.2013.774024  0.52
2013 Al-Gayyar MM, Mysona BA, Matragoon S, Abdelsaid MA, El-Azab MF, Shanab AY, Ha Y, Smith SB, Bollinger KE, El-Remessy AB. Diabetes and overexpression of proNGF cause retinal neurodegeneration via activation of RhoA pathway. Plos One. 8: e54692. PMID 23365678 DOI: 10.1371/journal.pone.0054692  0.52
2013 Tawfik A, Al-Shabrawey M, Roon P, Sonne S, Covar JA, Matragoon S, Ganapathy PS, Atherton SS, El-Remessy A, Ganapathy V, Smith SB. Alterations of retinal vasculature in cystathionine-Beta-synthase mutant mice, a model of hyperhomocysteinemia. Investigative Ophthalmology & Visual Science. 54: 939-49. PMID 23307965 DOI: 10.1167/iovs.12-10536  0.52
2013 Gnana-Prakasam JP, Veeranan-Karmegam R, Coothankandaswamy V, Reddy SK, Martin PM, Thangaraju M, Smith SB, Ganapathy V. Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 54: 63-71. PMID 23169885 DOI: 10.1167/iovs.12-10312  0.52
2013 Lewerenz J, Hewett SJ, Huang Y, Lambros M, Gout PW, Kalivas PW, Massie A, Smolders I, Methner A, Pergande M, Smith SB, Ganapathy V, Maher P. The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities. Antioxidants & Redox Signaling. 18: 522-55. PMID 22667998 DOI: 10.1089/ars.2011.4391  0.52
2012 Ha Y, Saul A, Tawfik A, Zorrilla EP, Ganapathy V, Smith SB. Diabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor 1. Molecular Vision. 18: 2860-70. PMID 23233788  0.52
2012 Gambhir D, Ananth S, Veeranan-Karmegam R, Elangovan S, Hester S, Jennings E, Offermanns S, Nussbaum JJ, Smith SB, Thangaraju M, Ganapathy V, Martin PM. GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy. Investigative Ophthalmology & Visual Science. 53: 2208-17. PMID 22427566 DOI: 10.1167/iovs.11-8447  0.52
2012 Yu M, Sturgill-Short G, Ganapathy P, Tawfik A, Peachey NS, Smith SB. Age-related changes in visual function in cystathionine-beta-synthase mutant mice, a model of hyperhomocysteinemia. Experimental Eye Research. 96: 124-31. PMID 22197750 DOI: 10.1016/j.exer.2011.12.011  0.52
2012 Bozard BR, Chothe PP, Tawfik A, Williams C, Fulzele S, Prasad PD, Martin PM, Ganapathy V, Smith SB. Regulation of proton-coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate. Glia. 60: 333-42. PMID 22072423 DOI: 10.1002/glia.22266  0.52
2012 Gnana-Prakasam JP, Tawfik A, Romej M, Ananth S, Martin PM, Smith SB, Ganapathy V. Iron-mediated retinal degeneration in haemojuvelin-knockout mice. The Biochemical Journal. 441: 599-608. PMID 21943374 DOI: 10.1042/BJ20111148  0.52
2012 Ananth S, Thakkar SV, Gnana-Prakasam JP, Martin PM, Ganapathy PS, Smith SB, Ganapathy V. Transport of the synthetic opioid peptide DADLE ([D-Ala2,D-Leu5]-enkephalin) in neuronal cells. Journal of Pharmaceutical Sciences. 101: 154-63. PMID 21905028 DOI: 10.1002/jps.22733  0.52
2012 Smith SB. Mechanisms of ER Stress in Retinal Disease Retina Fifth Edition. 1: 529-536. DOI: 10.1016/B978-1-4557-0737-9.00023-0  0.52
2011 Gnana-Prakasam JP, Reddy SK, Veeranan-Karmegam R, Smith SB, Martin PM, Ganapathy V. Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis. Investigative Ophthalmology & Visual Science. 52: 9279-86. PMID 22058337 DOI: 10.1167/iovs.11-8264  0.52
2011 Yang J, Hu X, Zimmerman M, Torres CM, Yang D, Smith SB, Liu K. Cutting edge: IRF8 regulates Bax transcription in vivo in primary myeloid cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 4426-30. PMID 21949018 DOI: 10.4049/jimmunol.1101034  0.52
2011 Ha Y, Saul A, Tawfik A, Williams C, Bollinger K, Smith R, Tachikawa M, Zorrilla E, Ganapathy V, Smith SB. Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (σR1). Investigative Ophthalmology & Visual Science. 52: 7749-60. PMID 21862648 DOI: 10.1167/iovs.11-8169  0.52
2011 Ganapathy PS, Perry RL, Tawfik A, Smith RM, Perry E, Roon P, Bozard BR, Ha Y, Smith SB. Homocysteine-mediated modulation of mitochondrial dynamics in retinal ganglion cells. Investigative Ophthalmology & Visual Science. 52: 5551-8. PMID 21642619 DOI: 10.1167/iovs.11-7256  0.52
2011 Babu E, Ananth S, Veeranan-Karmegam R, Coothankandaswamy V, Smith SB, Boettger T, Ganapathy V, Martin PM. Transport via SLC5A8 (SMCT1) is obligatory for 2-oxothiazolidine-4-carboxylate to enhance glutathione production in retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 52: 5749-57. PMID 21508099 DOI: 10.1167/iovs.10-6825  0.52
2011 Ganapathy PS, White RE, Ha Y, Bozard BR, McNeil PL, Caldwell RW, Kumar S, Black SM, Smith SB. The role of N-methyl-D-aspartate receptor activation in homocysteine-induced death of retinal ganglion cells. Investigative Ophthalmology & Visual Science. 52: 5515-24. PMID 21436276 DOI: 10.1167/iovs.10-6870  0.52
2011 Gnana-Prakasam JP, Ananth S, Prasad PD, Zhang M, Atherton SS, Martin PM, Smith SB, Ganapathy V. Expression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epithelium. Investigative Ophthalmology & Visual Science. 52: 3751-8. PMID 21357408 DOI: 10.1167/iovs.10-6722  0.52
2011 Chothe PP, Gnana-Prakasam JP, Ananth S, Martin PM, Kannan R, Hinton DR, Smith SB, Ganapathy V. Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis. Biochemical and Biophysical Research Communications. 405: 244-9. PMID 21219868 DOI: 10.1016/j.bbrc.2011.01.018  0.52
2011 Ha Y, Dun Y, Thangaraju M, Duplantier J, Dong Z, Liu K, Ganapathy V, Smith SB. Sigma receptor 1 modulates endoplasmic reticulum stress in retinal neurons. Investigative Ophthalmology & Visual Science. 52: 527-40. PMID 20811050 DOI: 10.1167/iovs.10-5731  0.52
2010 Chintala S, Tóth K, Yin MB, Bhattacharya A, Smith SB, Ola MS, Cao S, Durrani FA, Zinia TR, Dean R, Slocum HK, Rustum YM. Downregulation of cystine transporter xc by irinotecan in human head and neck cancer FaDu xenografts. Chemotherapy. 56: 223-33. PMID 20551639 DOI: 10.1159/000316334  0.52
2010 Gnana-Prakasam JP, Martin PM, Smith SB, Ganapathy V. Expression and function of iron-regulatory proteins in retina. Iubmb Life. 62: 363-70. PMID 20408179 DOI: 10.1002/iub.326  0.52
2010 Ananth S, Zhuang L, Gopal E, Itagaki S, Ellappan B, Smith SB, Ganapathy V, Martin P. Diclofenac-induced stimulation of SMCT1 (SLC5A8) in a heterologous expression system: a RPE specific phenomenon. Biochemical and Biophysical Research Communications. 394: 75-80. PMID 20178774 DOI: 10.1016/j.bbrc.2010.02.109  0.52
2010 Bozard BR, Ganapathy PS, Duplantier J, Mysona B, Ha Y, Roon P, Smith R, Goldman ID, Prasad P, Martin PM, Ganapathy V, Smith SB. Molecular and biochemical characterization of folate transport proteins in retinal Müller cells. Investigative Ophthalmology & Visual Science. 51: 3226-35. PMID 20053979 DOI: 10.1167/iovs.09-4833  0.52
2010 Ganapathy PS, Dun Y, Ha Y, Duplantier J, Allen JB, Farooq A, Bozard BR, Smith SB. Sensitivity of staurosporine-induced differentiated RGC-5 cells to homocysteine. Current Eye Research. 35: 80-90. PMID 20021258 DOI: 10.3109/02713680903421194  0.52
2010 Chothe PP, Thakkar SV, Gnana-Prakasam JP, Ananth S, Hinton DR, Kannan R, Smith SB, Martin PM, Ganapathy V. Identification of a novel sodium-coupled oligopeptide transporter (SOPT2) in mouse and human retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 51: 413-20. PMID 19643969 DOI: 10.1167/iovs.09-4048  0.52
2009 Ganapathy PS, Roon P, Moister TK, Mysona B, Smith SB. Diabetes Accelerates Retinal Neuronal Cell Death In A Mouse Model of Endogenous Hyperhomocysteinemia. Ophthalmology and Eye Diseases. 1: 3-11. PMID 20407615  0.64
2009 Gnana-Prakasam JP, Thangaraju M, Liu K, Ha Y, Martin PM, Smith SB, Ganapathy V. Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchanger. The Biochemical Journal. 424: 243-52. PMID 19715555 DOI: 10.1042/BJ20090424  0.52
2009 Ganapathy PS, Moister B, Roon P, Mysona BA, Duplantier J, Dun Y, Moister TK, Farley MJ, Prasad PD, Liu K, Smith SB. Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-beta-synthase mutant mouse. Investigative Ophthalmology & Visual Science. 50: 4460-70. PMID 19357353 DOI: 10.1167/iovs.09-3402  0.52
2009 Thangaraju M, Cresci GA, Liu K, Ananth S, Gnanaprakasam JP, Browning DD, Mellinger JD, Smith SB, Digby GJ, Lambert NA, Prasad PD, Ganapathy V. GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. Cancer Research. 69: 2826-32. PMID 19276343 DOI: 10.1158/0008-5472.CAN-08-4466  0.52
2009 Gnana-Prakasam JP, Zhang M, Martin PM, Atherton SS, Smith SB, Ganapathy V. Expression of the iron-regulatory protein haemojuvelin in retina and its regulation during cytomegalovirus infection. The Biochemical Journal. 419: 533-43. PMID 19191760 DOI: 10.1042/BJ20082240  0.52
2009 Mysona B, Dun Y, Duplantier J, Ganapathy V, Smith SB. Effects of hyperglycemia and oxidative stress on the glutamate transporters GLAST and system xc- in mouse retinal Müller glial cells. Cell and Tissue Research. 335: 477-88. PMID 19156441 DOI: 10.1007/s00441-008-0742-1  0.64
2009 Ananth S, Karunakaran S, Martin PM, Nagineni CN, Hooks JJ, Smith SB, Prasad PD, Ganapathy V. Functional identification of a novel transport system for endogenous and synthetic opioid peptides in the rabbit conjunctival epithelial cell line CJVE. Pharmaceutical Research. 26: 1226-35. PMID 18781380 DOI: 10.1007/s11095-008-9709-x  0.52
2008 Samaddar JS, Gaddy VT, Duplantier J, Thandavan SP, Shah M, Smith MJ, Browning D, Rawson J, Smith SB, Barrett JT, Schoenlein PV. A role for macroautophagy in protection against 4-hydroxytamoxifen-induced cell death and the development of antiestrogen resistance. Molecular Cancer Therapeutics. 7: 2977-87. PMID 18790778 DOI: 10.1158/1535-7163.MCT-08-0447  0.52
2008 Umapathy NS, Dun Y, Martin PM, Duplantier JN, Roon P, Prasad P, Smith SB, Ganapathy V. Expression and function of system N glutamine transporters (SN1/SN2 or SNAT3/SNAT5) in retinal ganglion cells. Investigative Ophthalmology & Visual Science. 49: 5151-60. PMID 18689705 DOI: 10.1167/iovs.08-2245  0.64
2008 Smith SB, Duplantier J, Dun Y, Mysona B, Roon P, Martin PM, Ganapathy V. In vivo protection against retinal neurodegeneration by sigma receptor 1 ligand (+)-pentazocine. Investigative Ophthalmology & Visual Science. 49: 4154-61. PMID 18469181 DOI: 10.1167/iovs.08-1824  0.64
2008 Gnana-Prakasam JP, Martin PM, Mysona BA, Roon P, Smith SB, Ganapathy V. Hepcidin expression in mouse retina and its regulation via lipopolysaccharide/Toll-like receptor-4 pathway independent of Hfe. The Biochemical Journal. 411: 79-88. PMID 18042040 DOI: 10.1042/BJ20071377  0.52
2008 Dun Y, Duplantier J, Roon P, Martin PM, Ganapathy V, Smith SB. Serine racemase expression and D-serine content are developmentally regulated in neuronal ganglion cells of the retina. Journal of Neurochemistry. 104: 970-8. PMID 17976164 DOI: 10.1111/j.1471-4159.2007.05015.x  0.64
2007 Umapathy NS, Gnana-Prakasam JP, Martin PM, Mysona B, Dun Y, Smith SB, Ganapathy V, Prasad PD. Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types. Investigative Ophthalmology & Visual Science. 48: 5299-305. PMID 17962486 DOI: 10.1167/iovs.07-0288  0.64
2007 Dun Y, Thangaraju M, Prasad P, Ganapathy V, Smith SB. Prevention of excitotoxicity in primary retinal ganglion cells by (+)-pentazocine, a sigma receptor-1 specific ligand. Investigative Ophthalmology & Visual Science. 48: 4785-94. PMID 17898305 DOI: 10.1167/iovs.07-0343  0.52
2007 Keating E, Gonçalves P, Lemos C, Costa F, Campos I, Smith SB, Bridges CC, Martel F. Progesterone inhibits folic acid transport in human trophoblasts. The Journal of Membrane Biology. 216: 143-52. PMID 17687501 DOI: 10.1007/s00232-007-9057-5  0.52
2007 Martin PM, Dun Y, Mysona B, Ananth S, Roon P, Smith SB, Ganapathy V. Expression of the sodium-coupled monocarboxylate transporters SMCT1 (SLC5A8) and SMCT2 (SLC5A12) in retina. Investigative Ophthalmology & Visual Science. 48: 3356-63. PMID 17591909 DOI: 10.1167/iovs.06-0888  0.64
2007 Gopal E, Miyauchi S, Martin PM, Ananth S, Roon P, Smith SB, Ganapathy V. Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract. Pharmaceutical Research. 24: 575-84. PMID 17245649 DOI: 10.1007/s11095-006-9176-1  0.64
2007 Gopal E, Miyauchi S, Martin PM, Ananth S, Srinivas SR, Smith SB, Prasad PD, Ganapathy V. Expression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell lines. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G402-8. PMID 16973915 DOI: 10.1152/ajpgi.00371.2006  0.52
2006 Thangaraju M, Gopal E, Martin PM, Ananth S, Smith SB, Prasad PD, Sterneck E, Ganapathy V. SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases. Cancer Research. 66: 11560-4. PMID 17178845 DOI: 10.1158/0008-5472.CAN-06-1950  0.52
2006 Jiang G, Mysona B, Dun Y, Gnana-Prakasam JP, Pabla N, Li W, Dong Z, Ganapathy V, Smith SB. Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells. Investigative Ophthalmology & Visual Science. 47: 5576-82. PMID 17122151 DOI: 10.1167/iovs.06-0608  0.64
2006 Martin PM, Gnana-Prakasam JP, Roon P, Smith RG, Smith SB, Ganapathy V. Expression and polarized localization of the hemochromatosis gene product HFE in retinal pigment epithelium. Investigative Ophthalmology & Visual Science. 47: 4238-44. PMID 17003411 DOI: 10.1167/iovs.06-0026  0.64
2006 Thangaraju M, Ananth S, Martin PM, Roon P, Smith SB, Sterneck E, Prasad PD, Ganapathy V. c/ebpdelta Null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney. The Journal of Biological Chemistry. 281: 26769-73. PMID 16873376 DOI: 10.1074/jbc.C600189200  0.64
2006 Kutty RK, Samuel W, Chen S, Vijayasarathy C, Dun Y, Mysona B, Wiggert B, Smith SB. Immunofluorescence analysis of the expression of Norpeg (Rai14) in retinal Müller and ganglion cells. Neuroscience Letters. 404: 294-8. PMID 16806700 DOI: 10.1016/j.neulet.2006.06.006  0.64
2006 Martin PM, Gopal E, Ananth S, Zhuang L, Itagaki S, Prasad BM, Smith SB, Prasad PD, Ganapathy V. Identity of SMCT1 (SLC5A8) as a neuron-specific Na+-coupled transporter for active uptake of L-lactate and ketone bodies in the brain. Journal of Neurochemistry. 98: 279-88. PMID 16805814 DOI: 10.1111/j.1471-4159.2006.03878.x  0.52
2005 Umapathy NS, Li W, Mysona BA, Smith SB, Ganapathy V. Expression and function of glutamine transporters SN1 (SNAT3) and SN2 (SNAT5) in retinal Müller cells. Investigative Ophthalmology & Visual Science. 46: 3980-7. PMID 16249471 DOI: 10.1167/iovs.05-0488  0.52
2005 Naggar H, Van Ells TK, Ganapathy V, Smith SB. Regulation of reduced-folate transporter-1 in retinal pigment epithelial cells by folate. Current Eye Research. 30: 35-44. PMID 15875363  0.52
2004 George RL, Huang W, Naggar HA, Smith SB, Ganapathy V. Transport of N-acetylaspartate via murine sodium/dicarboxylate cotransporter NaDC3 and expression of this transporter and aspartoacylase II in ocular tissues in mouse. Biochimica Et Biophysica Acta. 1690: 63-9. PMID 15337171 DOI: 10.1016/j.bbadis.2004.05.009  0.52
2004 Martin PM, Roon P, Van Ells TK, Ganapathy V, Smith SB. Death of retinal neurons in streptozotocin-induced diabetic mice. Investigative Ophthalmology & Visual Science. 45: 3330-6. PMID 15326158 DOI: 10.1167/iovs.04-0247  0.64
2004 Bridges CC, Hu H, Miyauchi S, Siddaramappa UN, Ganapathy ME, Ignatowicz L, Maddox DM, Smith SB, Ganapathy V. Induction of cystine-glutamate transporter xc- by human immunodeficiency virus type 1 transactivator protein tat in retinal pigment epithelium. Investigative Ophthalmology & Visual Science. 45: 2906-14. PMID 15326101 DOI: 10.1167/iovs.03-1355  0.52
2004 Gopal E, Fei YJ, Sugawara M, Miyauchi S, Zhuang L, Martin P, Smith SB, Prasad PD, Ganapathy V. Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate. The Journal of Biological Chemistry. 279: 44522-32. PMID 15322102 DOI: 10.1074/jbc.M405365200  0.52
2004 Martin PM, Ola MS, Agarwal N, Ganapathy V, Smith SB. The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate. Brain Research. Molecular Brain Research. 123: 66-75. PMID 15046867 DOI: 10.1016/j.molbrainres.2003.12.019  0.52
2004 Ganapathy V, Smith SB, Prasad PD. SLC19: the folate/thiamine transporter family. PflüGers Archiv : European Journal of Physiology. 447: 641-6. PMID 14770311 DOI: 10.1007/s00424-003-1068-1  0.52
2004 El-Sherbeny A, Naggar H, Miyauchi S, Ola MS, Maddox DM, Martin PM, Ganapathy V, Smith SB. Osmoregulation of taurine transporter function and expression in retinal pigment epithelial, ganglion, and müller cells. Investigative Ophthalmology & Visual Science. 45: 694-701. PMID 14744916  0.52
2004 Hatanaka T, Haramura M, Fei YJ, Miyauchi S, Bridges CC, Ganapathy PS, Smith SB, Ganapathy V, Ganapathy ME. Transport of amino acid-based prodrugs by the Na+- and Cl(-) -coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery. The Journal of Pharmacology and Experimental Therapeutics. 308: 1138-47. PMID 14617696 DOI: 10.1124/jpet.103.057109  0.52
2003 Naggar H, Fei YJ, Ganapathy V, Smith SB. Regulation of reduced-folate transporter-1 (RFT-1) by homocysteine and identity of transport systems for homocysteine uptake in retinal pigment epithelial (RPE) cells. Experimental Eye Research. 77: 687-97. PMID 14609557  0.52
2003 Hu H, Miyauchi S, Bridges CC, Smith SB, Ganapathy V. Identification of a novel Na+- and Cl--coupled transport system for endogenous opioid peptides in retinal pigment epithelium and induction of the transport system by HIV-1 Tat. The Biochemical Journal. 375: 17-22. PMID 12924983 DOI: 10.1042/BJ20031059  0.52
2003 Maddox DM, Manlapat A, Roon P, Prasad P, Ganapathy V, Smith SB. Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of the developing forebrain, hindbrain, neural tube, craniofacial region, eye, limb buds and heart. Bmc Developmental Biology. 3: 6. PMID 12887734 DOI: 10.1186/1471-213X-3-6  0.64
2003 Inoue K, Zhuang L, Maddox DM, Smith SB, Ganapathy V. Human sodium-coupled citrate transporter, the orthologue of Drosophila Indy, as a novel target for lithium action. The Biochemical Journal. 374: 21-6. PMID 12826022 DOI: 10.1042/BJ20030827  0.52
2002 Ola MS, Moore P, Maddox D, El-Sherbeny A, Huang W, Roon P, Agarwal N, Ganapathy V, Smith SB. Analysis of sigma receptor (sigmaR1) expression in retinal ganglion cells cultured under hyperglycemic conditions and in diabetic mice. Brain Research. Molecular Brain Research. 107: 97-107. PMID 12425939  0.64
2002 Wang Y, Smith SB, Ogilvie JM, McCool DJ, Sarthy V. Ciliary neurotrophic factor induces glial fibrillary acidic protein in retinal Müller cells through the JAK/STAT signal transduction pathway. Current Eye Research. 24: 305-12. PMID 12324870 DOI: 10.1076/ceyr.24.4.305.8408  0.52
2002 Bridges CC, El-Sherbeny A, Ola MS, Ganapathy V, Smith SB. Transcellular transfer of folate across the retinal pigment epithelium. Current Eye Research. 24: 129-38. PMID 12187485 DOI: 10.1076/ceyr.24.2.129.8167  0.52
2002 Inoue K, Zhuang L, Maddox DM, Smith SB, Ganapathy V. Structure, function, and expression pattern of a novel sodium-coupled citrate transporter (NaCT) cloned from mammalian brain. The Journal of Biological Chemistry. 277: 39469-76. PMID 12177002 DOI: 10.1074/jbc.M207072200  0.52
2002 Hatanaka T, Huang W, Nakanishi T, Bridges CC, Smith SB, Prasad PD, Ganapathy ME, Ganapathy V. Transport of D-serine via the amino acid transporter ATB(0,+) expressed in the colon. Biochemical and Biophysical Research Communications. 291: 291-5. PMID 11846403 DOI: 10.1006/bbrc.2002.6441  0.52
2002 Naggar H, Ola MS, Moore P, Huang W, Bridges CC, Ganapathy V, Smith SB. Downregulation of reduced-folate transporter by glucose in cultured RPE cells and in RPE of diabetic mice. Investigative Ophthalmology & Visual Science. 43: 556-63. PMID 11818404  0.52
2002 Smith SB. Diabetic retinopathy and the NMDA receptor Drug News and Perspectives. 15: 226-232. DOI: 10.1358/dnp.2002.15.4.840055  0.52
2001 Bridges CC, Ola MS, Prasad PD, El-Sherbeny A, Ganapathy V, Smith SB. Regulation of taurine transporter expression by NO in cultured human retinal pigment epithelial cells. American Journal of Physiology. Cell Physiology. 281: C1825-36. PMID 11698241  0.52
2001 Bridges CC, El-Sherbeny A, Roon P, Ola MS, Kekuda R, Ganapathy V, Camero RS, Cameron PL, Smith SB. A comparison of caveolae and caveolin-1 to folate receptor alpha in retina and retinal pigment epithelium. The Histochemical Journal. 33: 149-58. PMID 11508338 DOI: 10.1023/A:1017991925821  0.52
2001 Bridges CC, Kekuda R, Wang H, Prasad PD, Mehta P, Huang W, Smith SB, Ganapathy V. Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 42: 47-54. PMID 11133847  0.52
2001 Kutty RK, Kutty G, Samuel W, Duncan T, Bridges CC, El-Sherbeeny A, Nagineni CN, Smith SB, Wiggert B. Molecular characterization and developmental expression of NORPEG, a novel gene induced by retinoic acid. The Journal of Biological Chemistry. 276: 2831-40. PMID 11042181 DOI: 10.1074/jbc.M007421200  0.52
1997 Evans BL, Smith SB. Analysis of esterification of retinoids in the retinal pigmented epithelium of the Mitf-vit (vitiligo) mutant mouse Molecular Vision. 3: 11. PMID 9383334  0.52
1997 Sarthy V, Brodjian SJ, Smith SB. Ciliary neurotrophic factor (CNTF) induces reactive gliosis and gfap expression in müller cells Investigative Ophthalmology and Visual Science. 38: S590.  0.52
1995 Smith SB. Evidence of a difference in photoreceptor cell loss in the peripheral versus posterior regions of the vitiligo (C57BL/6J-mivit/mivit) mouse retina Experimental Eye Research. 60: 333-336. PMID 7789413 DOI: 10.1016/S0014-4835(05)80115-0  0.52
1995 Smith SB, Defoe DM. Autoradiographic and biochemical assessment of rod outer segment renewal in the vitiligo (C57BL/6-mivit/mivit) mouse model of retinal degeneration Experimental Eye Research. 60: 91-96. PMID 7720808 DOI: 10.1016/S0014-4835(05)80086-7  0.52
1995 Nir I, Ransom N, Smith SB. Ultrastructural features of retinal dystrophy in mutant vitiligo mice Experimental Eye Research. 61: 363-377. PMID 7556499 DOI: 10.1016/S0014-4835(05)80130-7  0.52
1994 Smith SB, Hamasaki DI. Electroretinographic study of the C57BL/6-mi(vit)/mi(vit) mouse model of retinal degeneration Investigative Ophthalmology and Visual Science. 35: 3119-3123. PMID 8206731  0.52
1992 Smith SB. C57BL 6J- vit vit mouse model of retinal degeneration: Light microscopic analysis and evaluation of rhodopsin levels Experimental Eye Research. 55: 903-910. PMID 1486944 DOI: 10.1016/0014-4835(92)90017-M  0.52
1991 Smith SB, O'Brien PJ. Acylation and glycosylation of rhodopsin in the rd mouse Experimental Eye Research. 52: 599-606. PMID 2065728 DOI: 10.1016/0014-4835(91)90062-J  0.52
1988 Smith SB, O'Brien PJ. Biochemical characterization of retinal protein and phospholipid synthesis in mice exposed transplacentally to N-methyl-N-nitrosourea Experimental Eye Research. 47: 713-725. PMID 3197772 DOI: 10.1016/0014-4835(88)90039-5  0.52
1986 Smith SB, Yielding KL. Retinal degeneration in the mouse. A model induced transplaceatally by methylnitrosourea Experimental Eye Research. 43: 791-801. PMID 3803463 DOI: 10.1016/S0014-4835(86)80010-0  0.52
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