Michael Cascio - Publications

University of Pittsburgh, Pittsburgh, PA, United States 

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Pope D, Cascio M. Neprilysin inhibitors provide insight into its specificity and therapeutic potential Drug Design and Discovery in Alzheimer's Disease. 598-622. DOI: 10.1016/B978-0-12-803959-5.50013-1  1
2014 Liu Z, Szarecka A, Yonkunas M, Speranskiy K, Kurnikova M, Cascio M. Crosslinking constraints and computational models as complementary tools in modeling the extracellular domain of the glycine receptor. Plos One. 9: e102571. PMID 25025226 DOI: 10.1371/Journal.Pone.0102571  1
2014 Pope D, Madura JD, Cascio M. β-Amyloid and neprilysin computational studies identify critical residues implicated in binding specificity. Journal of Chemical Information and Modeling. 54: 1157-65. PMID 24650257 DOI: 10.1021/Ci500015M  1
2013 Divito EB, Cascio M. Metabolism, physiology, and analyses of primary fatty acid amides. Chemical Reviews. 113: 7343-53. PMID 23927536 DOI: 10.1021/Cr300363B  1
2013 Janjic JM, Patel SK, Patrick MJ, Pollock JA, DiVito E, Cascio M. Suppressing inflammation from inside out with novel NIR visible perfluorocarbon nanotheranostics Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8596. DOI: 10.1117/12.2004625  1
2012 Divito EB, Davic AP, Johnson ME, Cascio M. Electrospray ionization and collision induced dissociation mass spectrometry of primary fatty acid amides. Analytical Chemistry. 84: 2388-94. PMID 22283789 DOI: 10.1021/Ac203158U  1
2011 Goss JR, Cascio M, Goins WF, Huang S, Krisky DM, Clarke RJ, Johnson JW, Yokoyama H, Yoshimura N, Gold MS, Glorioso JC. HSV delivery of a ligand-regulated endogenous ion channel gene to sensory neurons results in pain control following channel activation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 500-6. PMID 21081904 DOI: 10.1038/Mt.2010.246  1
2010 Jameel NM, Thirunavukkarasu C, Murase N, Cascio M, Prelich J, Yang S, Harvey SA, Gandhi CR. Constitutive release of powerful antioxidant-scavenging activity by hepatic stellate cells: protection of hepatocytes from ischemia/reperfusion injury. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 16: 1400-9. PMID 21117250 DOI: 10.1002/Lt.22172  1
2010 Ruthstein S, Stone KM, Cunningham TF, Ji M, Cascio M, Saxena S. Pulsed electron spin resonance resolves the coordination site of Cu²(+) ions in α1-glycine receptor. Biophysical Journal. 99: 2497-506. PMID 20959090 DOI: 10.1016/J.Bpj.2010.08.050  1
2010 Tseng CN, Zhang L, Wu SL, Wang WF, Wang ZZ, Cascio M. Asparagine of z8 insert is critical for the affinity, conformation, and acetylcholine receptor-clustering activity of neural agrin. The Journal of Biological Chemistry. 285: 27641-51. PMID 20566625 DOI: 10.1074/Jbc.M110.130625  1
2009 Van Laar VS, Mishizen AJ, Cascio M, Hastings TG. Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells. Neurobiology of Disease. 34: 487-500. PMID 19332121 DOI: 10.1016/J.Nbd.2009.03.004  1
2008 Liu Z, Ramanoudjame G, Liu D, Fox RO, Jayaraman V, Kurnikova M, Cascio M. Overexpression and functional characterization of the extracellular domain of the human alpha1 glycine receptor. Biochemistry. 47: 9803-10. PMID 18710260 DOI: 10.1021/Bi800659X  1
2008 Dukes AA, Van Laar VS, Cascio M, Hastings TG. Changes in endoplasmic reticulum stress proteins and aldolase A in cells exposed to dopamine. Journal of Neurochemistry. 106: 333-46. PMID 18384645 DOI: 10.1111/J.1471-4159.2008.05392.X  1
2008 Cheng MH, Coalson RD, Cascio M, Kurnikova M. Computational prediction of ion permeation characteristics in the glycine receptor modified by photo-sensitive compounds. Journal of Computer-Aided Molecular Design. 22: 563-70. PMID 18368498 DOI: 10.1007/S10822-008-9200-0  1
2008 Van Laar VS, Dukes AA, Cascio M, Hastings TG. Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: implications for Parkinson disease. Neurobiology of Disease. 29: 477-89. PMID 18226537 DOI: 10.1016/J.Nbd.2007.11.007  1
2008 Zhang B, Sun C, Jin S, Cascio M, Montelaro RC. Mapping of equine lentivirus receptor 1 residues critical for equine infectious anemia virus envelope binding. Journal of Virology. 82: 1204-13. PMID 18032504 DOI: 10.1128/Jvi.01393-07  1
2008 Cheng MH, Coalson RD, Cascio M. Molecular dynamics simulations of ethanol binding to the transmembrane domain of the glycine receptor: implications for the channel potentiation mechanism. Proteins. 71: 972-81. PMID 18004757 DOI: 10.1002/Prot.21784  1
2007 Srinivasan R, Huang S, Chaudhry S, Sculptoreanu A, Krisky D, Cascio M, Friedman PA, de Groat WC, Wolfe D, Glorioso JC. An HSV vector system for selection of ligand-gated ion channel modulators. Nature Methods. 4: 733-9. PMID 17676048 DOI: 10.1038/Nmeth1077  1
2007 Cheng MH, Cascio M, Coalson RD. Homology modeling and molecular dynamics simulations of the alpha1 glycine receptor reveals different states of the channel. Proteins. 68: 581-93. PMID 17469203 DOI: 10.1002/Prot.21435  1
2007 Speranskiy K, Cascio M, Kurnikova M. Homology modeling and molecular dynamics simulations of the glycine receptor ligand binding domain. Proteins. 67: 950-60. PMID 17357155 DOI: 10.1002/Prot.21251  1
2007 Iyer AK, Tran KT, Borysenko CW, Cascio M, Camacho CJ, Blair HC, Bahar I, Wells A. Tenascin cytotactin epidermal growth factor-like repeat binds epidermal growth factor receptor with low affinity. Journal of Cellular Physiology. 211: 748-58. PMID 17311283 DOI: 10.1002/Jcp.20986  1
2006 Cascio M. Modulating inhibitory ligand-gated ion channels. The Aaps Journal. 8: E353-61. PMID 16796386 DOI: 10.1007/Bf02854906  1
2005 Cascio M. Connexins and their environment: effects of lipids composition on ion channels. Biochimica Et Biophysica Acta. 1711: 142-53. PMID 15955299 DOI: 10.1016/J.Bbamem.2004.12.001  1
2005 Cheng MH, Cascio M, Coalson RD. Theoretical studies of the M2 transmembrane segment of the glycine receptor: models of the open pore structure and current-voltage characteristics. Biophysical Journal. 89: 1669-80. PMID 15951389 DOI: 10.1529/Biophysj.105.060368  1
2005 Alajez NM, Schmielau J, Alter MD, Cascio M, Finn OJ. Therapeutic potential of a tumor-specific, MHC-unrestricted T-cell receptor expressed on effector cells of the innate and the adaptive immune system through bone marrow transduction and immune reconstitution. Blood. 105: 4583-9. PMID 15746083 DOI: 10.1182/Blood-2004-10-3848  1
2005 Deslouches B, Phadke SM, Lazarevic V, Cascio M, Islam K, Montelaro RC, Mietzner TA. De novo generation of cationic antimicrobial peptides: influence of length and tryptophan substitution on antimicrobial activity. Antimicrobial Agents and Chemotherapy. 49: 316-22. PMID 15616311 DOI: 10.1128/Aac.49.1.316-322.2005  1
2004 Shangary S, Oliver CL, Tillman TS, Cascio M, Johnson DE. Sequence and helicity requirements for the proapoptotic activity of Bax BH3 peptides. Molecular Cancer Therapeutics. 3: 1343-54. PMID 15542773  1
2004 Cascio M, Mayor JA, Kaplan RS. Analysis of the secondary structure of the cys-less yeast mitochondrial citrate transport protein and four single-cys variants by circular dichroism. Journal of Bioenergetics and Biomembranes. 36: 429-38. PMID 15534390 DOI: 10.1023/B:Jobb.0000047325.48943.71  1
2004 Kim SI, Voshol H, van Oostrum J, Hastings TG, Cascio M, Glucksman MJ. Neuroproteomics: expression profiling of the brain's proteomes in health and disease. Neurochemical Research. 29: 1317-31. PMID 15176488 DOI: 10.1023/B:Nere.0000023618.35579.7C  1
2004 Cascio M. Structure and function of the glycine receptor and related nicotinicoid receptors. The Journal of Biological Chemistry. 279: 19383-6. PMID 15023997 DOI: 10.1074/Jbc.R300035200  1
2003 Tillman TS, Cascio M. Effects of membrane lipids on ion channel structure and function. Cell Biochemistry and Biophysics. 38: 161-90. PMID 12777713 DOI: 10.1385/Cbb:38:2:161  1
2003 Tseng CN, Zhang L, Cascio M, Wang ZZ. Calcium plays a critical role in determining the acetylcholine receptor-clustering activities of alternatively spliced isoforms of Agrin. The Journal of Biological Chemistry. 278: 17236-45. PMID 12621054 DOI: 10.1074/Jbc.M300282200  1
2002 Cascio M. Glycine receptors: lessons on topology and structural effects of the lipid bilayer. Biopolymers. 66: 359-68. PMID 12539264 DOI: 10.1002/Bip.10314  1
2002 Leite JF, Gribble B, Randolph N, Cascio M. In vitro interaction of the glycine receptor with the leptin receptor. Physiology & Behavior. 77: 565-9. PMID 12527000 DOI: 10.1016/S0031-9384(02)00912-5  1
2002 Cascio M, Rapaka RS. Structural biology and structural genomics/proteomics. The Journal of Peptide Research : Official Journal of the American Peptide Society. 60: 307-11. PMID 12464107 DOI: 10.1034/J.1399-3011.2002.21071.X  1
2002 Leite JF, Cascio M. Probing the topology of the glycine receptor by chemical modification coupled to mass spectrometry. Biochemistry. 41: 6140-8. PMID 11994009 DOI: 10.1021/Bi015895M  1
2001 Leite JF, Cascio M. Structure of ligand-gated ion channels: critical assessment of biochemical data supports novel topology. Molecular and Cellular Neurosciences. 17: 777-92. PMID 11358478 DOI: 10.1006/Mcne.2001.0984  1
2001 Cascio M, Shenkel S, Grodzicki RL, Sigworth FJ, Fox RO. Functional reconstitution and characterization of recombinant human alpha 1-glycine receptors. The Journal of Biological Chemistry. 276: 20981-8. PMID 11145968 DOI: 10.1074/jbc.M010968200  1
2000 Leite JF, Amoscato AA, Cascio M. Coupled proteolytic and mass spectrometry studies indicate a novel topology for the glycine receptor. The Journal of Biological Chemistry. 275: 13683-9. PMID 10788487 DOI: 10.1074/Jbc.275.18.13683  1
2000 Shao H, Cascio M, Tweardy DJ. Identification and characterization of CIS elements within the STAT3 gene regulating STAT3α and STAT3β mRNA ratios Blood. 96.  1
1999 Chakraborty A, Dyer KF, Cascio M, Mietzner TA, Tweardy DJ. Identification of a novel Stat3 recruitment and activation motif within the granulocyte colony-stimulating factor receptor. Blood. 93: 15-24. PMID 9864141 DOI: 10.1182/Blood.V93.1.15.401A46_15_24  1
1997 Lesauter J, Romero P, Cascio M, Silver R. Attachment Site of Grafted SCN Influences Precision of Restored Circadian Rhythm Journal of Biological Rhythms. 12: 327-338. PMID 9438881 DOI: 10.1177/074873049701200405  1
1995 Cascio M, Wallace BA. Effects of local environment on the circular dichroism spectra of polypeptides Analytical Biochemistry. 227: 90-100. PMID 7668397 DOI: 10.1006/Abio.1995.1257  1
1995 Cascio M, Kumar NM, Safarik R, Gilula NB. Physical characterization of gap junction membrane connexons (hemi-channels) isolated from rat liver Journal of Biological Chemistry. 270: 18643-18648. PMID 7629194 DOI: 10.1074/Jbc.270.31.18643  1
1995 Cascio M. [10] Baculovirus expression of receptors and channels Methods in Neurosciences. 25: 175-200. DOI: 10.1016/S1043-9471(05)80040-0  1
1994 Cascio M, Wallace BA. Red- and blue-shifting in the circular dichroism spectra of polypeptides due to dipole effects Protein Pept.Lett.. 1: 136-140.  1
1993 Cascio M, Schoppa NE, Grodzicki RL, Sigworth FJ, Fox RO. Functional expression and purification of a homomeric human alpha 1 glycine receptor in baculovirus-infected insect cells. The Journal of Biological Chemistry. 268: 22135-42. PMID 8408073  1
1993 Glucksman MJ, Roberts JL, Cascio M, Orlowski M. Neural endopeptidase 24.15 and mammalian zn metalloenzymes: Models with bacterial enzymes, structural and evolutionary considerations Protein Engineering, Design and Selection. 6: 43. DOI: 10.1093/Protein/6.Supplement.43-A  1
1990 Cascio M, Gogol E, Wallace BA. The secondary structure of gap junctions. Influence of isolation methods and proteolysis Journal of Biological Chemistry. 265: 2358-2364. PMID 1688853  1
1989 Cascio M, Glazer PA, Wallace BA. The secondary structure of human amyloid deposits as determined by circular dichroism spectroscopy Biochemical and Biophysical Research Communications. 162: 1162-1166. PMID 2764925 DOI: 10.1016/0006-291X(89)90795-X  1
1988 Cascio M, Wallace BA. Conformation of alamethicin in phospholipid vesicles: Implications for insertion models Proteins: Structure, Function and Genetics. 4: 89-98. PMID 3227017 DOI: 10.1002/Prot.340040203  1
1986 Wallace BA, Cascio M, Mielke DL. Evaluation of methods for the prediction of membrane protein secondary structures Proceedings of the National Academy of Sciences of the United States of America. 83: 9423-9427. PMID 3467313  1
1984 Cascio M, Wallace BA. The effects of environment on the conformation of the alamethicin membrane channel Annals of the New York Academy of Sciences. 527-529. DOI: 10.1111/J.1749-6632.1984.Tb13873.X  1
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