| Year |
Citation |
Score |
| 2018 |
Trofimova DN, Deeley RG. Structural studies of Multidrug Resistance Protein 1 (MRP1) using "almost" cysless template. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29572332 DOI: 10.1124/Dmd.117.078709 |
0.479 |
|
| 2012 |
Qin L, Tam SP, Deeley RG. Effect of multiple cysteine substitutions on the functionality of human multidrug resistance protein 1 expressed in human embryonic kidney 293 cells: identification of residues essential for function. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1403-13. PMID 22511347 DOI: 10.1124/Dmd.112.044867 |
0.578 |
|
| 2010 |
Rosenberg MF, Oleschuk CJ, Wu P, Mao Q, Deeley RG, Cole SP, Ford RC. Structure of a human multidrug transporter in an inward-facing conformation. Journal of Structural Biology. 170: 540-7. PMID 20109555 DOI: 10.1016/J.Jsb.2010.01.011 |
0.503 |
|
| 2009 |
Maeno K, Nakajima A, Conseil G, Rothnie A, Deeley RG, Cole SP. Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1411-20. PMID 19398503 DOI: 10.1124/Dmd.109.026633 |
0.528 |
|
| 2009 |
Conseil G, Rothnie AJ, Deeley RG, Cole SP. Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1). Molecular Pharmacology. 75: 397-406. PMID 19015228 DOI: 10.1124/Mol.108.052860 |
0.512 |
|
| 2008 |
Qin L, Zheng J, Grant CE, Jia Z, Cole SP, Deeley RG. Residues responsible for the asymmetric function of the nucleotide binding domains of multidrug resistance protein 1. Biochemistry. 47: 13952-65. PMID 19063607 DOI: 10.1021/Bi801532G |
0.558 |
|
| 2008 |
Grant CE, Gao M, DeGorter MK, Cole SP, Deeley RG. Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2571-81. PMID 18775981 DOI: 10.1124/Dmd.108.022491 |
0.704 |
|
| 2008 |
Rothnie A, Conseil G, Lau AY, Deeley RG, Cole SP. Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport. Molecular Pharmacology. 74: 1630-40. PMID 18768387 DOI: 10.1124/Mol.108.049080 |
0.535 |
|
| 2008 |
Bandler PE, Westlake CJ, Grant CE, Cole SP, Deeley RG. Identification of regions required for apical membrane localization of human multidrug resistance protein 2. Molecular Pharmacology. 74: 9-19. PMID 18381564 DOI: 10.1124/Mol.108.045674 |
0.495 |
|
| 2008 |
Létourneau IJ, Nakajima A, Deeley RG, Cole SP. Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter. Biochemical Pharmacology. 75: 1659-69. PMID 18336795 DOI: 10.1016/J.Bcp.2008.01.009 |
0.542 |
|
| 2008 |
Slot AJ, Wise DD, Deeley RG, Monks TJ, Cole SP. Modulation of human multidrug resistance protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) transport activities by endogenous and exogenous glutathione-conjugated catechol metabolites. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 552-60. PMID 18079363 DOI: 10.1124/Dmd.107.019661 |
0.459 |
|
| 2008 |
DeGorter MK, Conseil G, Deeley RG, Campbell RL, Cole SP. Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1). Biochemical and Biophysical Research Communications. 365: 29-34. PMID 17980150 DOI: 10.1016/J.Bbrc.2007.10.141 |
0.538 |
|
| 2007 |
Létourneau IJ, Slot AJ, Deeley RG, Cole SP. Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1372-9. PMID 17494643 DOI: 10.1124/Dmd.107.015479 |
0.532 |
|
| 2007 |
Zhang D, Cole SPC, Deeley RG. Mutational analysis of polar amino acid residues within predicted transmembrane helices of Multidrug Resistance Protein 1 (ABCC1): Effect on substrate specificity The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A196-A |
0.41 |
|
| 2006 |
Cole SP, Deeley RG. Transport of glutathione and glutathione conjugates by MRP1. Trends in Pharmacological Sciences. 27: 438-46. PMID 16820223 DOI: 10.1016/J.Tips.2006.06.008 |
0.51 |
|
| 2006 |
Deeley RG, Westlake C, Cole SP. Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins. Physiological Reviews. 86: 849-99. PMID 16816140 DOI: 10.1152/Physrev.00035.2005 |
0.569 |
|
| 2006 |
Tam SP, Mok L, Chimini G, Vasa M, Deeley RG. ABCA1 mediates high-affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cells. American Journal of Physiology. Cell Physiology. 291: C490-502. PMID 16611739 DOI: 10.1152/Ajpcell.00055.2006 |
0.471 |
|
| 2006 |
Rothnie A, Callaghan R, Deeley RG, Cole SP. Role of GSH in estrone sulfate binding and translocation by the multidrug resistance protein 1 (MRP1/ABCC1). The Journal of Biological Chemistry. 281: 13906-14. PMID 16565074 DOI: 10.1074/Jbc.M600869200 |
0.547 |
|
| 2006 |
Zhang DW, Nunoya K, Vasa M, Gu HM, Cole SP, Deeley RG. Mutational analysis of polar amino acid residues within predicted transmembrane helices 10 and 16 of multidrug resistance protein 1 (ABCC1): effect on substrate specificity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 539-46. PMID 16415113 DOI: 10.1124/Dmd.105.007740 |
0.47 |
|
| 2006 |
Deeley RG, Cole SP. Substrate recognition and transport by multidrug resistance protein 1 (ABCC1). Febs Letters. 580: 1103-11. PMID 16387301 DOI: 10.1016/J.Febslet.2005.12.036 |
0.512 |
|
| 2006 |
Conseil G, Deeley RG, Cole SP. Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1). The Journal of Biological Chemistry. 281: 43-50. PMID 16230346 DOI: 10.1074/Jbc.M510143200 |
0.538 |
|
| 2005 |
Wu P, Oleschuk CJ, Mao Q, Keller BO, Deeley RG, Cole SP. Analysis of human multidrug resistance protein 1 (ABCC1) by matrix-assisted laser desorption ionization/time of flight mass spectrometry: toward identification of leukotriene C4 binding sites. Molecular Pharmacology. 68: 1455-65. PMID 16105987 DOI: 10.1124/Mol.105.016576 |
0.565 |
|
| 2005 |
Létourneau IJ, Deeley RG, Cole SP. Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1). Pharmacogenetics and Genomics. 15: 647-57. PMID 16041243 DOI: 10.1097/01.Fpc.0000173484.51807.48 |
0.483 |
|
| 2005 |
Conseil G, Deeley RG, Cole SP. Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters. Pharmacogenetics and Genomics. 15: 523-33. PMID 16006996 DOI: 10.1097/01.Fpc.0000167333.38528.Ec |
0.494 |
|
| 2005 |
Leslie EM, Deeley RG, Cole SP. Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Toxicology and Applied Pharmacology. 204: 216-37. PMID 15845415 DOI: 10.1016/J.Taap.2004.10.012 |
0.518 |
|
| 2005 |
Létourneau IJ, Bowers RJ, Deeley RG, Cole SP. Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites. Toxicology Letters. 157: 9-19. PMID 15795089 DOI: 10.1016/J.Toxlet.2004.12.014 |
0.42 |
|
| 2005 |
Westlake CJ, Cole SP, Deeley RG. Role of the NH2-terminal membrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and trafficking. Molecular Biology of the Cell. 16: 2483-92. PMID 15772158 DOI: 10.1091/Mbc.E04-12-1113 |
0.52 |
|
| 2005 |
Payen L, Gao M, Westlake C, Theis A, Cole SP, Deeley RG. Functional interactions between nucleotide binding domains and leukotriene C4 binding sites of multidrug resistance protein 1 (ABCC1). Molecular Pharmacology. 67: 1944-53. PMID 15755910 DOI: 10.1124/Mol.104.007708 |
0.668 |
|
| 2005 |
Conseil G, Deeley RG, Cole SP. Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas. Biochemical Pharmacology. 69: 451-61. PMID 15652236 DOI: 10.1016/J.Bcp.2004.10.014 |
0.551 |
|
| 2004 |
Westlake CJ, Payen L, Gao M, Cole SP, Deeley RG. Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region. The Journal of Biological Chemistry. 279: 53571-83. PMID 15459206 DOI: 10.1074/Jbc.M402528200 |
0.668 |
|
| 2004 |
Zhang DW, Nunoya K, Vasa M, Gu HM, Theis A, Cole SP, Deeley RG. Transmembrane helix 11 of multidrug resistance protein 1 (MRP1/ABCC1): identification of polar amino acids important for substrate specificity and binding of ATP at nucleotide binding domain 1. Biochemistry. 43: 9413-25. PMID 15260484 DOI: 10.1021/Bi0495230 |
0.579 |
|
| 2004 |
Situ D, Haimeur A, Conseil G, Sparks KE, Zhang D, Deeley RG, Cole SP. Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transporter. The Journal of Biological Chemistry. 279: 38871-80. PMID 15208328 DOI: 10.1074/Jbc.M403832200 |
0.547 |
|
| 2004 |
Haimeur A, Conseil G, Deeley RG, Cole SP. Mutations of charged amino acids in or near the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein MRP1 (ABCC1). Molecular Pharmacology. 65: 1375-85. PMID 15155831 DOI: 10.1124/Mol.65.6.1375 |
0.536 |
|
| 2004 |
Koike K, Deeley RG, Cole SP. Mapping of the MRPm5 epitope to the cytosolic region between transmembrane helices 13 and 14 in the drug and organic anion transporter, MRP1 (ABCC1). Biochemical and Biophysical Research Communications. 315: 719-25. PMID 14975760 DOI: 10.1016/J.Bbrc.2004.01.111 |
0.561 |
|
| 2004 |
Haimeur A, Conseil G, Deeley RG, Cole SPC. The MRP-related and BCRP/ABCG2 multidrug resistance proteins: Biology, substrate specificity and regulation Current Drug Metabolism. 5: 21-53. PMID 14965249 DOI: 10.2174/1389200043489199 |
0.455 |
|
| 2004 |
Koike K, Conseil G, Leslie EM, Deeley RG, Cole SP. Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions. The Journal of Biological Chemistry. 279: 12325-36. PMID 14722114 DOI: 10.1074/jbc.M311435200 |
0.49 |
|
| 2004 |
Campbell JD, Koike K, Moreau C, Sansom MS, Deeley RG, Cole SP. Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1). The Journal of Biological Chemistry. 279: 463-8. PMID 14561746 DOI: 10.1074/jbc.M310711200 |
0.494 |
|
| 2003 |
Westlake CJ, Qian YM, Gao M, Vasa M, Cole SP, Deeley RG. Identification of the structural and functional boundaries of the multidrug resistance protein 1 cytoplasmic loop 3. Biochemistry. 42: 14099-113. PMID 14640677 DOI: 10.1021/Bi035333Y |
0.721 |
|
| 2003 |
Muredda M, Nunoya K, Burtch-Wright RA, Kurz EU, Cole SP, Deeley RG. Cloning and Characterization of the Murine and Rat mrp1 Promoter Regions. Molecular Pharmacology. 64: 1259-69. PMID 14573776 DOI: 10.1124/Mol.64.5.1259 |
0.436 |
|
| 2003 |
Zhang DW, Gu HM, Situ D, Haimeur A, Cole SP, Deeley RG. Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state. The Journal of Biological Chemistry. 278: 46052-63. PMID 12954620 DOI: 10.1074/Jbc.M308403200 |
0.582 |
|
| 2003 |
Ito K, Weigl KE, Deeley RG, Cole SP. Mutation of proline residues in the NH(2)-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function. Biochimica Et Biophysica Acta. 1615: 103-14. PMID 12948592 DOI: 10.1016/S0005-2736(03)00228-1 |
0.528 |
|
| 2003 |
Zhang DW, Gu HM, Vasa M, Muredda M, Cole SP, Deeley RG. Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of multidrug resistance protein 3. Biochemistry. 42: 9989-10000. PMID 12924948 DOI: 10.1021/Bi034462B |
0.507 |
|
| 2003 |
Payen LF, Gao M, Westlake CJ, Cole SP, Deeley RG. Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1). The Journal of Biological Chemistry. 278: 38537-47. PMID 12882957 DOI: 10.1074/Jbc.M305786200 |
0.695 |
|
| 2003 |
Nunoya K, Grant CE, Zhang D, Cole SP, Deeley RG. Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 1016-26. PMID 12867490 DOI: 10.1124/Dmd.31.8.1016 |
0.543 |
|
| 2003 |
Leslie EM, Létourneau IJ, Deeley RG, Cole SP. Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1). Biochemistry. 42: 5214-24. PMID 12731862 DOI: 10.1021/Bi027076N |
0.581 |
|
| 2003 |
Leslie EM, Bowers RJ, Deeley RG, Cole SP. Structural requirements for functional interaction of glutathione tripeptide analogs with the human multidrug resistance protein 1 (MRP1). The Journal of Pharmacology and Experimental Therapeutics. 304: 643-53. PMID 12538817 DOI: 10.1124/Jpet.102.044073 |
0.542 |
|
| 2003 |
Leslie EM, Deeley RG, Cole SP. Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 11-5. PMID 12485947 DOI: 10.1124/Dmd.31.1.11 |
0.539 |
|
| 2003 |
Oleschuk CJ, Deeley RG, Cole SP. Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G280-9. PMID 12388190 DOI: 10.1152/Ajpgi.00331.2002 |
0.528 |
|
| 2002 |
Koike K, Oleschuk CJ, Haimeur A, Olsen SL, Deeley RG, Cole SP. Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1. The Journal of Biological Chemistry. 277: 49495-503. PMID 12388549 DOI: 10.1074/Jbc.M206896200 |
0.56 |
|
| 2002 |
Haimeur A, Deeley RG, Cole SP. Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity. The Journal of Biological Chemistry. 277: 41326-33. PMID 12186871 DOI: 10.1074/Jbc.M206228200 |
0.538 |
|
| 2002 |
Qian YM, Grant CE, Westlake CJ, Zhang DW, Lander PA, Shepard RL, Dantzig AH, Cole SP, Deeley RG. Photolabeling of human and murine multidrug resistance protein 1 with the high affinity inhibitor [125I]LY475776 and azidophenacyl-[35S]glutathione. The Journal of Biological Chemistry. 277: 35225-31. PMID 12138119 DOI: 10.1074/Jbc.M206058200 |
0.589 |
|
| 2002 |
Conrad S, Kauffmann HM, Ito K, Leslie EM, Deeley RG, Schrenk D, Cole SP. A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance. Pharmacogenetics. 12: 321-30. PMID 12042670 DOI: 10.1097/00008571-200206000-00008 |
0.551 |
|
| 2002 |
Mao Q, Qiu W, Weigl KE, Lander PA, Tabas LB, Shepard RL, Dantzig AH, Deeley RG, Cole SP. GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain. The Journal of Biological Chemistry. 277: 28690-9. PMID 12034727 DOI: 10.1074/Jbc.M202182200 |
0.561 |
|
| 2002 |
Zhang DW, Cole SP, Deeley RG. Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17. The Journal of Biological Chemistry. 277: 20934-41. PMID 11925441 DOI: 10.1074/Jbc.M201311200 |
0.481 |
|
| 2001 |
Conrad S, Kauffmann HM, Ito K, Deeley RG, Cole SPC, Schrenk D. Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution Journal of Human Genetics. 46: 656-663. PMID 11721885 DOI: 10.1007/S100380170017 |
0.543 |
|
| 2001 |
Leslie EM, Deeley RG, Cole SPC. Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters Toxicology. 167: 3-23. PMID 11557126 DOI: 10.1016/S0300-483X(01)00454-1 |
0.534 |
|
| 2001 |
Qian YM, Qiu W, Gao M, Westlake CJ, Cole SP, Deeley RG. Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein. The Journal of Biological Chemistry. 276: 38636-44. PMID 11507101 DOI: 10.1074/Jbc.M107025200 |
0.718 |
|
| 2001 |
Ito K, Oleschuk CJ, Westlake C, Vasa MZ, Deeley RG, Cole SP. Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. The Journal of Biological Chemistry. 276: 38108-14. PMID 11500505 DOI: 10.1074/Jbc.M105160200 |
0.555 |
|
| 2001 |
Kurz EU, Cole SPC, Deeley RG. Identification of DNA-protein interactions in the 5′ flanking and 5′ untranslated regions of the human multidrug resistance protein (MRP1) gene: Evaluation of a putative antioxidant response element/AP-1 binding site Biochemical and Biophysical Research Communications. 285: 981-990. PMID 11467849 DOI: 10.1006/Bbrc.2001.5262 |
0.516 |
|
| 2001 |
Zhang DW, Cole SPC, Deeley RG. Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: Evidence for functional interaction between transmembrane helices 14 and 17 Journal of Biological Chemistry. 276: 34966-34974. PMID 11429411 DOI: 10.1074/Jbc.M105063200 |
0.525 |
|
| 2001 |
Young LC, Campling BG, Cole SPC, Deeley RG, Gerlach JH. Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: Correlation of protein levels with drug response and messenger RNA levels Clinical Cancer Research. 7: 1798-1804. PMID 11410522 |
0.302 |
|
| 2001 |
Leslie EM, Ito KI, Upadhyaya P, Hecht SS, Deeley RG, Cole SPC. Transport of the β-O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1): Requirement for glutathione or a non-sulfur-containing analog Journal of Biological Chemistry. 276: 27846-27854. PMID 11375986 DOI: 10.1074/Jbc.M102453200 |
0.463 |
|
| 2001 |
Leslie EM, Mao Q, Oleschuk CJ, Deeley RG, Cole SP. Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids. Molecular Pharmacology. 59: 1171-80. PMID 11306701 DOI: 10.1124/Mol.59.5.1171 |
0.522 |
|
| 2001 |
Rosenberg MF, Mao Q, Holzenburg A, Ford RC, Deeley RG, Cole SP. The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis. The Journal of Biological Chemistry. 276: 16076-82. PMID 11279022 DOI: 10.1074/Jbc.M100176200 |
0.444 |
|
| 2001 |
Ito KI, Olsen SL, Qiu W, Deeley RG, Cole SPC. Mutation of a Single Conserved Tryptophan in Multidrug Resistance Protein 1 (MRP1/ABCC1) Results in Loss of Drug Resistance and Selective Loss of Organic Anion Transport Journal of Biological Chemistry. 276: 15616-15624. PMID 11278867 DOI: 10.1074/Jbc.M011246200 |
0.6 |
|
| 2001 |
Zhang DW, Cole SPC, Deeley RG. Identification of an Amino Acid Residue in Multidrug Resistance Protein 1 Critical for Conferring Resistance to Anthracyclines Journal of Biological Chemistry. 276: 13231-13239. PMID 11278596 DOI: 10.1074/Jbc.M010008200 |
0.487 |
|
| 2001 |
Qian YM, Song WC, Cui H, Cole SPC, Deeley RG. Glutathione Stimulates Sulfated Estrogen Transport by Multidrug Resistance Protein 1 Journal of Biological Chemistry. 276: 6404-6411. PMID 11102445 DOI: 10.1074/jbc.M008251200 |
0.456 |
|
| 2000 |
Grant CE, May DL, Deeley RG. DNA binding and transcription activation by chicken interferon regulatory factor-3 (chIRF-3). Nucleic Acids Research. 28: 4790-9. PMID 11095692 DOI: 10.1093/Nar/28.23.4790 |
0.461 |
|
| 2000 |
May DL, Grant CE, Deeley RG. Cloning and promoter analysis of the chicken interferon regulatory factor-3 gene. Dna and Cell Biology. 19: 555-66. PMID 11034548 DOI: 10.1089/104454900439782 |
0.352 |
|
| 2000 |
Loe DW, Oleschuk CJ, Deeley RG, Cole SP. Structure-activity studies of verapamil analogs that modulate transport of leukotriene C(4) and reduced glutathione by multidrug resistance protein MRP1. Biochemical and Biophysical Research Communications. 275: 795-803. PMID 10973801 DOI: 10.1006/Bbrc.2000.3384 |
0.534 |
|
| 2000 |
Mao Q, Deeley RG, Cole SPC. Functional reconstitution of substrate transport by purified multidrug resistance protein MRP1 (ABCC1) in phospholipid vesicles Journal of Biological Chemistry. 275: 34166-34172. PMID 10942765 DOI: 10.1074/Jbc.M004584200 |
0.512 |
|
| 2000 |
Gao M, Cui HR, Loe DW, Grant CE, Almquist KC, Cole SP, Deeley RG. Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1. The Journal of Biological Chemistry. 275: 13098-108. PMID 10777615 DOI: 10.1074/Jbc.275.17.13098 |
0.706 |
|
| 2000 |
Loe DW, Deeley RG, Cole SPC. Verapamil stimulates glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1) Journal of Pharmacology and Experimental Therapeutics. 293: 530-538. PMID 10773025 |
0.419 |
|
| 2000 |
Prechtl S, Roellinghoff M, Scheper R, Cole SPC, Deeley RG, Lohoff M. The multidrug resistance protein 1: A functionally important activation marker for murine Th1 cells Journal of Immunology. 164: 754-761. PMID 10623820 DOI: 10.4049/Jimmunol.164.2.754 |
0.379 |
|
| 1999 |
Hipfner DR, Deeley RG, Cole SP. Structural, mechanistic and clinical aspects of MRP1. Biochimica Et Biophysica Acta. 1461: 359-76. PMID 10581367 DOI: 10.1016/S0005-2736(99)00168-6 |
0.514 |
|
| 1999 |
Mao Q, Leslie EM, Deeley RG, Cole SPC. ATPase activity of purified and reconstituted multidrug resistance protein MRP1 from drug-selected H69AR cells Biochimica Et Biophysica Acta - Biomembranes. 1461: 69-82. PMID 10556489 DOI: 10.1016/S0005-2736(99)00150-9 |
0.489 |
|
| 1999 |
Tejada ML, Jia Z, May D, Deeley RG. Determinants of the DNA-binding specificity of the Avian homeodomain protein, AKR. Dna and Cell Biology. 18: 791-804. PMID 10541438 DOI: 10.1089/104454999314935 |
0.754 |
|
| 1999 |
Stride BD, Cole SPC, Deeley RG. Localization of a substrate specificity domain in the multidrug resistance protein Journal of Biological Chemistry. 274: 22877-22883. PMID 10428874 DOI: 10.1074/Jbc.274.32.22877 |
0.557 |
|
| 1999 |
Ruetz S, Brault M, Kast C, Hemenway C, Heitman J, Grant CE, Cole SP, Deeley RG, Gros P. Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae. The Journal of Biological Chemistry. 274: 2592. PMID 10419350 |
0.324 |
|
| 1999 |
Hipfner DR, Mao Q, Qiu W, Leslie EM, Gao M, Deeley RG, Cole SP. Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein. The Journal of Biological Chemistry. 274: 15420-6. PMID 10336431 DOI: 10.1074/Jbc.274.22.15420 |
0.718 |
|
| 1999 |
Machiels JP, Govaerts AS, Guillaume T, Bayat B, Feyens AM, Lenoir E, Goeminne JC, Cole S, Deeley R, Caruso M, Bank A, Symann M, D'Hondt V. Retrovirus-mediated gene transfer of the human multidrug resistance-associated protein into hematopoietic cells protects mice from chemotherapy-induced leukopenia. Human Gene Therapy. 10: 801-11. PMID 10210147 DOI: 10.1089/10430349950018553 |
0.384 |
|
| 1998 |
Cole SPC, Deeley RG. Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP Bioessays. 20: 931-940. PMID 9872059 DOI: 10.1002/(Sici)1521-1878(199811)20:11<931::Aid-Bies8>3.0.Co;2-J |
0.587 |
|
| 1998 |
Loe DW, Deeley RG, Cole SPC. Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): Evidence for cotransport with reduced glutathione Cancer Research. 58: 5130-5136. PMID 9823323 |
0.465 |
|
| 1998 |
Hipfner DR, Gao M, Scheffer G, Scheper RJ, Deeley RG, Cole SP. Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP). British Journal of Cancer. 78: 1134-40. PMID 9820168 |
0.648 |
|
| 1998 |
Canitrot Y, Bichat F, Cole SP, Deeley RG, Gerlach JH, Bastian G, Arvelo F, Poupon MF. Multidrug resistance genes (MRP) and MDR1 expression in small cell lung cancer xenografts: relationship with response to chemotherapy. Cancer Letters. 130: 133-41. PMID 9751266 DOI: 10.1016/S0304-3835(98)00128-1 |
0.373 |
|
| 1998 |
Grant CE, Bhardwaj G, Cole SP, Deeley RG. Cloning, transfer, and characterization of multidrug resistance protein. Methods in Enzymology. 292: 594-607. PMID 9711585 DOI: 10.1016/S0076-6879(98)92046-8 |
0.425 |
|
| 1998 |
Gao M, Yamazaki M, Loe DW, Westlake CJ, Grant CE, Cole SP, Deeley RG. Multidrug resistance protein. Identification of regions required for active transport of leukotriene C4. The Journal of Biological Chemistry. 273: 10733-40. PMID 9553138 DOI: 10.1074/Jbc.273.17.10733 |
0.731 |
|
| 1998 |
Mohan WS, Chen ZQ, Zhang X, Khalili K, Honjo T, Deeley RG, Tam SP. Human S mu binding protein-2 binds to the drug response element and transactivates the human apoA-I promoter: role of gemfibrozil. Journal of Lipid Research. 39: 255-67. PMID 9507986 |
0.366 |
|
| 1997 |
Norris MD, Bordow SB, Haber PS, Marshall GM, Kavallaris M, Madafiglio J, Cohn SL, Salwen H, Schmidt ML, Hipfner DR, Cole SP, Deeley RG, Haber M. Evidence that the MYCN oncogene regulates MRP gene expression in neuroblastoma. European Journal of Cancer (Oxford, England : 1990). 33: 1911-6. PMID 9516823 DOI: 10.1016/S0959-8049(97)00284-0 |
0.335 |
|
| 1997 |
Deeley RG, Cole SPC. Function, evolution and structure of multidrug resistance protein (MRP) Seminars in Cancer Biology. 8: 193-204. PMID 9441948 DOI: 10.1006/Scbi.1997.0070 |
0.569 |
|
| 1997 |
Grant CE, Kurz EU, Cole SP, Deeley RG. Analysis of the intron-exon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA. Genomics. 45: 368-78. PMID 9344662 DOI: 10.1006/Geno.1997.4950 |
0.549 |
|
| 1997 |
Hipfner DR, Almquist KC, Leslie EM, Gerlach JH, Grant CE, Deeley RG, Cole SP. Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus. The Journal of Biological Chemistry. 272: 23623-30. PMID 9295302 DOI: 10.1074/Jbc.272.38.23623 |
0.527 |
|
| 1997 |
Stride BD, Grant CE, Loe DW, Hipfner DR, Cole SP, Deeley RG. Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells. Molecular Pharmacology. 52: 344-53. PMID 9281595 DOI: 10.1124/Mol.52.3.344 |
0.51 |
|
| 1997 |
Loe DW, Stewart RK, Massey TE, Deeley RG, Cole SPC. ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene Molecular Pharmacology. 51: 1034-1041. PMID 9187270 DOI: 10.1124/Mol.51.6.1034 |
0.532 |
|
| 1997 |
Lohoff M, Sommer F, Prechtl S, Roellinghoff M, Schmitt E, Gradehandt G, Rohwer P, Stride B, Cole SP, Deeley RG. A multidrug-resistance-protein (MRP)-like transmembrane pump is differentially expressed in resting, but not activated Th1 and Th2 cells Immunology Letters. 56: 353. DOI: 10.1016/S0165-2478(97)86429-2 |
0.394 |
|
| 1996 |
Gao M, Loe DW, Grant CE, Cole SP, Deeley RG. Reconstitution of ATP-dependent leukotriene C4 transport by Co-expression of both half-molecules of human multidrug resistance protein in insect cells. The Journal of Biological Chemistry. 271: 27782-7. PMID 8910374 DOI: 10.1074/Jbc.271.44.27782 |
0.696 |
|
| 1996 |
Cole SP, Deeley RG. Multidrug resistance associated with overexpression of MRP Cancer Treatment and Research. 87: 39-62. PMID 8886448 DOI: 10.1007/978-1-4613-1267-3_2 |
0.355 |
|
| 1996 |
Kuss BJ, Deeley RG, Cole SPC, Willman CL, Kopecky KJ, Wolman SR, Eyre HJ, Callen DF. The biological significance of the multidrug resistance gene MRP in inversion 16 leukemias Leukemia and Lymphoma. 20: 357-364. PMID 8833390 DOI: 10.3109/10428199609052416 |
0.366 |
|
| 1996 |
Lautier D, Canitrot Y, Deeley RG, Cole SPC. Multidrug resistance mediated by the multidrug resistance protein (MRP) gene Biochemical Pharmacology. 52: 967-977. PMID 8831715 DOI: 10.1016/0006-2952(96)00450-9 |
0.524 |
|
| 1996 |
Hipfner DR, Almquist KC, Stride BD, Deeley RG, Cole SP. Location of a protease-hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1. Cancer Research. 56: 3307-14. PMID 8764126 |
0.367 |
|
| 1996 |
Loe DW, Deeley RG, Cole SPC. Biology of the multidrug resistance-associated protein, MRP European Journal of Cancer. 32: 945-957. PMID 8763335 DOI: 10.1016/0959-8049(96)00046-9 |
0.411 |
|
| 1996 |
Leier I, Jedlitschky G, Buchholz U, Center M, Cole SPC, Deeley RG, Keppler D. ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump Biochemical Journal. 314: 433-437. PMID 8670053 DOI: 10.1042/Bj3140433 |
0.467 |
|
| 1996 |
Stride BD, Valdimarsson G, Gerlach JH, Wilson GM, Cole SPC, Deeley RG. Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter Molecular Pharmacology. 49: 962-971. PMID 8649356 |
0.508 |
|
| 1996 |
Ruetz S, Brault M, Kast C, Hemenway C, Heitman J, Grant CE, Cole SP, Deeley RG, Gros P. Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae. The Journal of Biological Chemistry. 271: 4154-60. PMID 8626756 DOI: 10.1074/Jbc.271.8.4154 |
0.539 |
|
| 1996 |
Loe DW, Almquist KC, Deeley RG, Cole SPC. ATP-dependent 17β-estradiol 17-(β-D-glucuronide) transport by multidrug resistance protein (MRP): Inhibition by cholestatic steroids Journal of Biological Chemistry. 271: 9683-9689. PMID 8621644 DOI: 10.1074/Jbc.271.16.9683 |
0.52 |
|
| 1996 |
Loe DW, Almquist KC, Deeley RG, Cole SPC. Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles: Demonstration of glutathione-dependent vincristine transport Journal of Biological Chemistry. 271: 9675-9682. PMID 8621643 DOI: 10.1074/Jbc.271.16.9675 |
0.51 |
|
| 1996 |
Stewart AJ, Canitrot Y, Baracchini E, Dean NM, Deeley RG, Cole SP. Reduction of expression of the multidrug resistance protein (MRP) in human tumor cells by antisense phosphorothioate oligonucleotides. Biochemical Pharmacology. 51: 461-9. PMID 8619891 DOI: 10.1016/0006-2952(95)02220-1 |
0.508 |
|
| 1996 |
Ross DD, Doyle LA, Schiffer CA, Lee EJ, Grant CE, Cole SP, Deeley RG, Yang W, Tong Y. Expression of multidrug resistance-associated protein (MRP) mRNA in blast cells from acute myeloid leukemia (AML) patients. Leukemia. 10: 48-55. PMID 8558937 |
0.317 |
|
| 1995 |
Almquist KC, Loe DW, Hipfner DR, Mackie JE, Cole SP, Deeley RG. Characterization of the M(r) 190,000 multidrug resistance protein (MRP) in drug-selected and transfected human tumor cell. Cancer Research. 55: 102-10. PMID 7805019 |
0.369 |
|
| 1995 |
Hasegawa S, Abe T, Naito S, Kotoh S, Kumazawa J, Hipfner DR, Deeley RG, Cole SP, Kuwano M. Expression of multidrug resistance-associated protein (MRP), MDR1 and DNA topoisomerase II in human multidrug-resistant bladder cancer cell lines. British Journal of Cancer. 71: 907-13. PMID 7734314 DOI: 10.1038/bjc.1995.177 |
0.319 |
|
| 1995 |
Ryan AK, Tejada ML, May DL, Dubaova M, Deeley RG. Isolation and characterization of the chicken homeodomain protein AKR. Nucleic Acids Research. 23: 3252-9. PMID 7667102 DOI: 10.1093/Nar/23.16.3252 |
0.758 |
|
| 1995 |
Wilson GM, Deeley RG. An Episomal Expression Vector System for Monitoring Sequence-Specific Effects on mRNA Stability in Human Cell Lines Plasmid. 33: 198-207. PMID 7568467 DOI: 10.1006/Plas.1995.1021 |
0.319 |
|
| 1995 |
Grant CE, Vasa MZ, Deeley RG. cIRF-3, a new member of the interferon regulatory factor (IRF) family that is rapidly and transiently induced by dsRNA. Nucleic Acids Research. 23: 2137-46. PMID 7541908 DOI: 10.1093/Nar/23.12.2137 |
0.394 |
|
| 1995 |
Tejada ML, Deeley RG. Cloning of an avian antithrombin: developmental and hormonal regulation of expression. Thrombosis and Haemostasis. 73: 654-61. PMID 7495074 DOI: 10.1055/S-0038-1653836 |
0.715 |
|
| 1994 |
Grant CE, Valdimarsson G, Hipfner DR, Almquist KC, Cole SP, Deeley RG. Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs. Cancer Research. 54: 357-61. PMID 8275468 |
0.336 |
|
| 1994 |
Tam SP, Deeley RG. Regulation of apolipoprotein A-I gene expression by phenobarbital in the human hepatocarcinoma cell line, Hep3B Atherosclerosis. 105: 235-243. PMID 8003099 DOI: 10.1016/0021-9150(94)90054-X |
0.372 |
|
| 1994 |
Leier I, Jedlitschky G, Buchholz U, Cole SPC, Deeley RG, Keppler D. The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates Journal of Biological Chemistry. 269: 27807-27810. PMID 7961706 |
0.436 |
|
| 1994 |
Cole SP, Sparks KE, Fraser K, Loe DW, Grant CE, Wilson GM, Deeley RG. Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells. Cancer Research. 54: 5902-10. PMID 7954421 |
0.342 |
|
| 1994 |
Ryan AK, Schrader TJ, Wright RB, Buchanan L, Deeley RG. Characterization of protein interactions with positive and negative elements regulating the apoVLDLII gene Dna and Cell Biology. 13: 987-999. PMID 7945939 DOI: 10.1089/Dna.1994.13.987 |
0.408 |
|
| 1994 |
Kuss BJ, Eyre HJ, Lane SA, Nancarrow JK, Whitmore SA, Callen DF, Deeley RG, Cole SPC, Willman CL, Kopecky KL, Kopecky K, Wolman SR. Deletion of gene for multidrug resistance in acute myeloid leukaemia with inversion in chromosome 16: prognostic implications The Lancet. 343: 1531-1534. PMID 7911871 DOI: 10.1016/S0140-6736(94)92938-6 |
0.304 |
|
| 1994 |
Sumizawa T, Chuman Y, Sakamoto H, Iemura K, Almquist KC, Deeley RG, Cole SPC, Akiyama Si. Non-P-glycoprotein-mediated multidrug-resistant human KB cells selected in medium containing adriamycin, cepharanthine, and mezerein Somatic Cell and Molecular Genetics. 20: 423-435. PMID 7825064 DOI: 10.1007/Bf02257459 |
0.336 |
|
| 1993 |
Grant CE, Deeley RG. Cloning and characterization of chicken YB-1: regulation of expression in the liver. Molecular and Cellular Biology. 13: 4186-96. PMID 8321222 DOI: 10.1128/Mcb.13.7.4186 |
0.46 |
|
| 1993 |
Cole SPC, Deeley RG. Multidrug resistance-associated protein: Sequence correction [7] Science. 260: 879. PMID 8098549 DOI: 10.1126/Science.8098549 |
0.385 |
|
| 1992 |
Hoodless PA, Ryan AK, Schrader TJ, Deeley RG. Characterization of liver-enriched proteins binding to a developmentally demethylated site flanking the avian apoVLDLII gene Dna and Cell Biology. 11: 755-765. PMID 1457044 DOI: 10.1089/Dna.1992.11.755 |
0.44 |
|
| 1992 |
Cole SP, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Stewart AJ, Kurz EU, Duncan AM, Deeley RG. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science (New York, N.Y.). 258: 1650-4. PMID 1360704 DOI: 10.1126/Science.1360704 |
0.487 |
|
| 1990 |
Hoodless PA, Roy RN, Ryan AK, Haché RJ, Vasa MZ, Deeley RG. Developmental regulation of specific protein interactions with an enhancerlike binding site far upstream from the avian very-low-density apolipoprotein II gene. Molecular and Cellular Biology. 10: 154-64. PMID 2294400 DOI: 10.1128/Mcb.10.1.154 |
0.45 |
|
| 1990 |
HOODLESS P, DEELEY R. Purification of a protein binding far upstream of the avian apovldlii gene Cell Biology International Reports. 14: 150. DOI: 10.1016/0309-1651(90)90702-Z |
0.415 |
|
| 1987 |
Hache RJG, Tam SP, Cochrane A, Nesheim M, Deeley RG. Long-term effects of estrogen on avian liver: Estrogen-inducible switch in expression of nuclear, hormone-binding proteins Molecular and Cellular Biology. 7: 3538-3547. PMID 3683392 DOI: 10.1128/Mcb.7.10.3538 |
0.365 |
|
| 1986 |
Tam SP, Archer TK, Deeley RG. Biphasic effects of estrogen on apolipoprotein synthesis in human hepatoma cells: Mechanism of antagonism by testosterone Proceedings of the National Academy of Sciences of the United States of America. 83: 3111-3115. PMID 3085084 DOI: 10.1073/Pnas.83.10.3111 |
0.327 |
|
| 1975 |
Meyers M, Blasi F, Bruni CB, Deeley RG, Kovach JS, Levinthal M, Mullinix KP, Vogel T, Goldberger RF. Specific binding of the first enzyme for histidine biosynthesis to the DNA of the histidine operon Nucleic Acids Research. 2: 2021-2036. PMID 1052526 DOI: 10.1093/Nar/2.11.2021 |
0.357 |
|
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