Jennifer E Van Eyk - Publications

Affiliations: 
1996-2003 Physiology Queen's University, Canada, Kingston, Ontario, Canada 
 2003-2014 Johns Hopkins University, Baltimore, MD 
 2014- Cedars-Sinai, Los Angeles, CA, United States 
Area:
Biochemistry
Website:
http://bio.csmc.edu/view/15171/Jennifer-Van-Eyk.aspx

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Fert-Bober J, Murray CI, Parker SJ, Van Eyk JE. Precision Profiling of the Cardiovascular Post-Translationally Modified Proteome: Where There Is a Will, There Is a Way. Circulation Research. 122: 1221-1237. PMID 29700069 DOI: 10.1161/CIRCRESAHA.118.310966  0.01
2018 Chung HS, Murray CI, Van Eyk JE. A Proteomics Workflow for Dual Labeling Biotin Switch Assay to Detect and Quantify Protein S-Nitroylation. Methods in Molecular Biology (Clifton, N.J.). 1747: 89-101. PMID 29600453 DOI: 10.1007/978-1-4939-7695-9_8  0.04
2015 Chung HS, Murray CI, Venkatraman V, Crowgey EL, Rainer PP, Cole RN, Bomgarden RD, Rogers JC, Balkan W, Hare JM, Kass DA, Van Eyk JE. Dual Labeling Biotin Switch Assay to Reduce Bias Derived From Different Cysteine Subpopulations: A Method to Maximize S-Nitrosylation Detection. Circulation Research. 117: 846-57. PMID 26338901 DOI: 10.1161/CIRCRESAHA.115.307336  0.04
2015 Bausch-Fluck D, Hofmann A, Bock T, Frei AP, Cerciello F, Jacobs A, Moest H, Omasits U, Gundry RL, Yoon C, Schiess R, Schmidt A, Mirkowska P, Härtlová A, Van Eyk JE, et al. A mass spectrometric-derived cell surface protein atlas. Plos One. 10: e0121314. PMID 25894527 DOI: 10.1371/journal.pone.0121314  0.04
2015 Wijnker PJ, Li Y, Zhang P, Foster DB, dos Remedios C, Van Eyk JE, Stienen GJ, Murphy AM, van der Velden J. A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis. Journal of Molecular and Cellular Cardiology. 82: 93-103. PMID 25771144 DOI: 10.1016/j.yjmcc.2015.03.006  0.12
2014 Kirk JA, Holewinski RJ, Kooij V, Agnetti G, Tunin RS, Witayavanitkul N, de Tombe PP, Gao WD, Van Eyk J, Kass DA. Cardiac resynchronization sensitizes the sarcomere to calcium by reactivating GSK-3β. The Journal of Clinical Investigation. 124: 129-38. PMID 24292707 DOI: 10.1172/JCI69253  1
2013 Murray CI, Chung HS, Uhrigshardt H, Van Eyk JE. Quantification of mitochondrial S-nitrosylation by CysTMT⁶ switch assay. Methods in Molecular Biology (Clifton, N.J.). 1005: 169-79. PMID 23606257 DOI: 10.1007/978-1-62703-386-2_14  0.01
2013 Chung HS, Wang SB, Venkatraman V, Murray CI, Van Eyk JE. Cysteine oxidative posttranslational modifications: emerging regulation in the cardiovascular system. Circulation Research. 112: 382-92. PMID 23329793 DOI: 10.1161/CIRCRESAHA.112.268680  0.01
2013 Wang SB, Murray CI, Chung HS, Van Eyk JE. Redox regulation of mitochondrial ATP synthase. Trends in Cardiovascular Medicine. 23: 14-8. PMID 23312134 DOI: 10.1016/j.tcm.2012.08.005  0.01
2012 Murray CI, Van Eyk JE. A twist on quantification: measuring the site occupancy of S-nitrosylation. Circulation Research. 111: 1253-5. PMID 23104874 DOI: 10.1161/CIRCRESAHA.112.278721  0.04
2012 Murray CI, Van Eyk JE. Chasing cysteine oxidative modifications: proteomic tools for characterizing cysteine redox status. Circulation. Cardiovascular Genetics. 5: 591. PMID 23074338 DOI: 10.1161/CIRCGENETICS.111.961425  0.01
2012 Gao WD, Murray CI, Tian Y, Zhong X, DuMond JF, Shen X, Stanley BA, Foster DB, Wink DA, King SB, Van Eyk JE, Paolocci N. Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function. Circulation Research. 111: 1002-11. PMID 22851540 DOI: 10.1161/CIRCRESAHA.112.270827  0.08
2012 Husberg C, Agnetti G, Holewinski RJ, Christensen G, Van Eyk JE. Dephosphorylation of cardiac proteins in vitro - a matter of phosphatase specificity. Proteomics. 12: 973-8. PMID 22522803 DOI: 10.1002/pmic.201100116  1
2012 Gundry RL, Riordon DR, Tarasova Y, Chuppa S, Bhattacharya S, Juhasz O, Wiedemeier O, Milanovich S, Noto FK, Tchernyshyov I, Raginski K, Bausch-Fluck D, Tae HJ, Marshall S, Duncan SA, ... ... Van Eyk JE, et al. A cell surfaceome map for immunophenotyping and sorting pluripotent stem cells. Molecular & Cellular Proteomics : McP. 11: 303-16. PMID 22493178 DOI: 10.1074/mcp.M112.018135  1
2012 Chung BM, Murray CI, Van Eyk JE, Coulombe PA. Identification of novel interaction between annexin A2 and keratin 17: evidence for reciprocal regulation. The Journal of Biological Chemistry. 287: 7573-81. PMID 22235123 DOI: 10.1074/jbc.M111.301549  0.01
2012 Murray CI, Uhrigshardt H, O'Meally RN, Cole RN, Van Eyk JE. Identification and quantification of S-nitrosylation by cysteine reactive tandem mass tag switch assay. Molecular & Cellular Proteomics : McP. 11: M111.013441. PMID 22126794 DOI: 10.1074/mcp.M111.013441  0.04
2011 O'Rourke B, Van Eyk JE, Foster DB. Mitochondrial protein phosphorylation as a regulatory modality: implications for mitochondrial dysfunction in heart failure. Congestive Heart Failure (Greenwich, Conn.). 17: 269-82. PMID 22103918 DOI: 10.1111/j.1751-7133.2011.00266.x  0.36
2011 Pan X, Kane LA, Van Eyk JE, Coulombe PA. Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion. The Journal of Biological Chemistry. 286: 42403-13. PMID 22006917 DOI: 10.1074/jbc.M111.302042  0.01
2011 Wang SB, Foster DB, Rucker J, O'Rourke B, Kass DA, Van Eyk JE. Redox regulation of mitochondrial ATP synthase: implications for cardiac resynchronization therapy. Circulation Research. 109: 750-7. PMID 21817160 DOI: 10.1161/CIRCRESAHA.111.246124  0.12
2011 Cammarato A, Ahrens CH, Alayari NN, Qeli E, Rucker J, Reedy MC, Zmasek CM, Gucek M, Cole RN, Van Eyk JE, Bodmer R, O'Rourke B, Bernstein SI, Foster DB. A mighty small heart: the cardiac proteome of adult Drosophila melanogaster. Plos One. 6: e18497. PMID 21541028 DOI: 10.1371/journal.pone.0018497  0.08
2011 Murray CI, Kane LA, Uhrigshardt H, Wang SB, Van Eyk JE. Site-mapping of in vitro S-nitrosation in cardiac mitochondria: implications for cardioprotection. Molecular & Cellular Proteomics : McP. 10: M110.004721. PMID 21036925 DOI: 10.1074/mcp.M110.004721  0.01
2010 Patterson SD, Van Eyk JE, Banks RE. Report from the Wellcome Trust/EBA “Perspectives in Clinical Proteomics” retreat--a strategy to implement next-generation proteomic analyses to the clinic for patient benefit: pathway to translation. Proteomics. Clinical Applications. 4: 883-7. PMID 21179889 DOI: 10.1002/prca.201000113  1
2010 Balabaskaran Nina P, Dudkina NV, Kane LA, van Eyk JE, Boekema EJ, Mather MW, Vaidya AB. Highly divergent mitochondrial ATP synthase complexes in Tetrahymena thermophila. Plos Biology. 8: e1000418. PMID 20644710 DOI: 10.1371/journal.pbio.1000418  1
2010 Lin Y, Fu Q, Zhu J, Miller JM, Van Eyk JE. Development of a qualitative sequential immunoassay for characterizing the intrinsic properties of circulating cardiac troponin I. Clinical Chemistry. 56: 1307-19. PMID 20558636 DOI: 10.1373/clinchem.2009.135186  1
2010 Gundry RL, Tchernyshyov I, Sheng S, Tarasova Y, Raginski K, Boheler KR, Van Eyk JE. Expanding the mouse embryonic stem cell proteome: combining three proteomic approaches. Proteomics. 10: 2728-32. PMID 20512790 DOI: 10.1002/pmic.201000039  0.36
2010 Hesketh GG, Shah MH, Halperin VL, Cooke CA, Akar FG, Yen TE, Kass DA, Machamer CE, Van Eyk JE, Tomaselli GF. Ultrastructure and regulation of lateralized connexin43 in the failing heart. Circulation Research. 106: 1153-63. PMID 20167932 DOI: 10.1161/CIRCRESAHA.108.182147  0.12
2010 Agnetti G, Kaludercic N, Kane LA, Elliott ST, Guo Y, Chakir K, Samantapudi D, Paolocci N, Tomaselli GF, Kass DA, Van Eyk JE. Modulation of mitochondrial proteome and improved mitochondrial function by biventricular pacing of dyssynchronous failing hearts. Circulation. Cardiovascular Genetics. 3: 78-87. PMID 20160199 DOI: 10.1161/CIRCGENETICS.109.871236  0.01
2010 Galińska A, Hatch V, Craig R, Murphy AM, Van Eyk JE, Wang CL, Lehman W, Foster DB. The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments. Circulation Research. 106: 705-11. PMID 20035081 DOI: 10.1161/CIRCRESAHA.109.210047  0.16
2010 Kane LA, Youngman MJ, Jensen RE, Van Eyk JE. Phosphorylation of the F(1)F(o) ATP synthase beta subunit: functional and structural consequences assessed in a model system. Circulation Research. 106: 504-13. PMID 20035080 DOI: 10.1161/CIRCRESAHA.109.214155  0.01
2010 Köttgen A, Hwang SJ, Larson MG, Van Eyk JE, Fu Q, Benjamin EJ, Dehghan A, Glazer NL, Kao WH, Harris TB, Gudnason V, Shlipak MG, Yang Q, Coresh J, Levy D, et al. Uromodulin levels associate with a common UMOD variant and risk for incident CKD. Journal of the American Society of Nephrology : Jasn. 21: 337-44. PMID 19959715 DOI: 10.1681/ASN.2009070725  1
2010 Matt P, Huso DL, Habashi J, Holm T, Doyle J, Schoenhoff F, Liu G, Black J, Van Eyk JE, Dietz HC. Murine model of surgically induced acute aortic dissection type A. The Journal of Thoracic and Cardiovascular Surgery. 139: 1041-7. PMID 19910001 DOI: 10.1016/j.jtcvs.2009.08.039  1
2009 Gundry RL, White MY, Murray CI, Kane LA, Fu Q, Stanley BA, Van Eyk JE. Preparation of proteins and peptides for mass spectrometry analysis in a bottom-up proteomics workflow. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit10.25. PMID 19816929 DOI: 10.1002/0471142727.mb1025s88  0.2
2009 Hesketh GG, Van Eyk JE, Tomaselli GF. Mechanisms of gap junction traffic in health and disease. Journal of Cardiovascular Pharmacology. 54: 263-72. PMID 19701097 DOI: 10.1097/FJC.0b013e3181ba0811  0.24
2009 Gundry RL, Raginski K, Tarasova Y, Tchernyshyov I, Bausch-Fluck D, Elliott ST, Boheler KR, Van Eyk JE, Wollscheid B. The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation. Molecular & Cellular Proteomics : McP. 8: 2555-69. PMID 19656770 DOI: 10.1074/mcp.M900195-MCP200  0.08
2009 Murray CI, Barrett M, Van Eyk JE. Assessment of ProteoExtract subcellular fractionation kit reveals limited and incomplete enrichment of nuclear subproteome from frozen liver and heart tissue. Proteomics. 9: 3934-8. PMID 19637233 DOI: 10.1002/pmic.200701170  0.04
2009 Hsu K, Chi N, Gucek M, Van Eyk JE, Cole RN, Lin M, Foster DB. Miltenberger blood group antigen type III (Mi.III) enhances the expression of band 3. Blood. 114: 1919-28. PMID 19564639 DOI: 10.1182/blood-2008-12-195180  0.12
2009 Foster DB, Van Eyk JE, Marbán E, O'Rourke B. Redox signaling and protein phosphorylation in mitochondria: progress and prospects. Journal of Bioenergetics and Biomembranes. 41: 159-68. PMID 19440831 DOI: 10.1007/s10863-009-9217-7  0.2
2009 Kane LA, Van Eyk JE. Post-translational modifications of ATP synthase in the heart: biology and function. Journal of Bioenergetics and Biomembranes. 41: 145-50. PMID 19399597 DOI: 10.1007/s10863-009-9218-6  0.01
2009 Stastna M, Abraham MR, Van Eyk JE. Cardiac stem/progenitor cells, secreted proteins, and proteomics. Febs Letters. 583: 1800-7. PMID 19303873 DOI: 10.1016/j.febslet.2009.03.026  1
2009 Gundry RL, White MY, Nogee J, Tchernyshyov I, Van Eyk JE. Assessment of albumin removal from an immunoaffinity spin column: critical implications for proteomic examination of the albuminome and albumin-depleted samples. Proteomics. 9: 2021-8. PMID 19294703 DOI: 10.1002/pmic.200800686  0.56
2008 Gundry RL, Boheler KR, Van Eyk JE, Wollscheid B. A novel role for proteomics in the discovery of cell-surface markers on stem cells: Scratching the surface. Proteomics. Clinical Applications. 2: 892-903. PMID 19526049 DOI: 10.1002/prca.200780122  0.52
2008 Foster DB, O'Rourke B, Van Eyk JE. What can mitochondrial proteomics tell us about cardioprotection afforded by preconditioning? Expert Review of Proteomics. 5: 633-6. PMID 18937553 DOI: 10.1586/14789450.5.5.633  0.48
2008 Tarasov KV, Tarasova YS, Tam WL, Riordon DR, Elliott ST, Kania G, Li J, Yamanaka S, Crider DG, Testa G, Li RA, Lim B, Stewart CL, Liu Y, Van Eyk JE, et al. B-MYB is essential for normal cell cycle progression and chromosomal stability of embryonic stem cells. Plos One. 3: e2478. PMID 18575582 DOI: 10.1371/journal.pone.0002478  1
2008 Agnetti G, Bezstarosti K, Dekkers DHW, Verhoeven AJM, Giordano E, Guarnieri C, Caldarera CM, Van Eyk JE, Lamers JMJ. Proteomic profiling of endothelin-1-stimulated hypertrophic cardiomyocytes reveals the increase of four different desmin species and α-B-crystallin Biochimica Et Biophysica Acta - Proteins and Proteomics. 1784: 1068-1076. PMID 18472024 DOI: 10.1016/j.bbapap.2008.04.003  1
2008 Mathivanan S, Ahmed M, Ahn NG, Alexandre H, Amanchy R, Andrews PC, Bader JS, Balgley BM, Bantscheff M, Bennett KL, Björling E, Blagoev B, Bose R, Brahmachari SK, Burlingame AS, ... Van Eyk J, et al. Human Proteinpedia enables sharing of human protein data. Nature Biotechnology. 26: 164-7. PMID 18259167 DOI: 10.1038/nbt0208-164  1
2008 Warburton S, White MY, Van Eyk JE, Cotter RJ, Ping P, Dunn MJ, Vondriska TM. Cardiovascular Initiative of the Human Proteome Organisation, 5th Workshop October 2007, Seoul, Korea. Proteomics. 8: 924-6. PMID 18240139 DOI: 10.1002/pmic.200701083  1
2007 Gundry RL, Fu Q, Jelinek CA, Van Eyk JE, Cotter RJ. Investigation of an albumin-enriched fraction of human serum and its albuminome. Proteomics. Clinical Applications. 1: 73-88. PMID 20204147 DOI: 10.1002/prca.200600276  1
2007 Gundry RL, Van Eyk JE. Unraveling the complexity of circulating forms of brain natriuretic peptide. Clinical Chemistry. 53: 1181-2. PMID 17582147 DOI: 10.1373/clinchem.2007.086611  1
2007 Agnetti G, Kane LA, Guarnieri C, Caldarera CM, Van Eyk JE. Proteomic technologies in the study of kinases: novel tools for the investigation of PKC in the heart. Pharmacological Research. 55: 511-22. PMID 17548206 DOI: 10.1016/j.phrs.2007.04.012  1
2007 Fu Q, Bovenkamp DE, Van Eyk JE. A rapid, economical, and reproducible method for human serum delipidation and albumin and IgG removal for proteomic analysis. Methods in Molecular Biology (Clifton, N.J.). 357: 365-71. PMID 17172702 DOI: 10.1385/1-59745-214-9:365  1
2007 Bovenkamp DE, Stanley BA, Van Eyk JE. Optimization of cardiac troponin I pull-down by IDM affinity beads and SELDI. Methods in Molecular Biology (Clifton, N.J.). 357: 91-102. PMID 17172682 DOI: 10.1385/1-59745-214-9:91  1
2007 Kane LA, Neverova I, Van Eyk JE. Subfractionation of heart tissue: the "in sequence" myofilament protein extraction of myocardial tissue. Methods in Molecular Biology (Clifton, N.J.). 357: 87-90. PMID 17172681 DOI: 10.1385/1-59745-214-9:87  1
2006 Narolska NA, Piroddi N, Belus A, Boontje NM, Scellini B, Deppermann S, Zaremba R, Musters RJ, dos Remedios C, Jaquet K, Foster DB, Murphy AM, van Eyk JE, Tesi C, Poggesi C, et al. Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle. Circulation Research. 99: 1012-20. PMID 17023673 DOI: 10.1161/01.RES.0000248753.30340.af  0.01
2006 Kane LA, Yung CK, Agnetti G, Neverova I, Van Eyk JE. Optimization of paper bridge loading for 2-DE analysis in the basic pH region: application to the mitochondrial subproteome. Proteomics. 6: 5683-7. PMID 17022103 DOI: 10.1002/pmic.200600267  1
2006 Yang CG, Granite SJ, Van Eyk JE, Winslow RL. MASCOT HTML and XML parser: an implementation of a novel object model for protein identification data. Proteomics. 6: 5688-93. PMID 17006878 DOI: 10.1002/pmic.200600157  1
2006 Arrell DK, Elliott ST, Kane LA, Guo Y, Ko YH, Pedersen PL, Robinson J, Murata M, Murphy AM, Marbán E, Van Eyk JE. Proteomic analysis of pharmacological preconditioning: novel protein targets converge to mitochondrial metabolism pathways. Circulation Research. 99: 706-14. PMID 16946135 DOI: 10.1161/01.RES.0000243995.74395.f8  0.08
2006 Fu Q, Van Eyk JE. Proteomics and heart disease: identifying biomarkers of clinical utility. Expert Review of Proteomics. 3: 237-49. PMID 16608436 DOI: 10.1586/14789450.3.2.237  1
2006 Wilkins MR, Appel RD, Van Eyk JE, Chung MC, Görg A, Hecker M, Huber LA, Langen H, Link AJ, Paik YK, Patterson SD, Pennington SR, Rabilloud T, Simpson RJ, Weiss W, et al. Guidelines for the next 10 years of proteomics. Proteomics. 6: 4-8. PMID 16400714 DOI: 10.1002/pmic.200500856  1
2005 Buscemi N, Murray C, Doherty-Kirby A, Lajoie G, Sussman MA, Van Eyk JE. Myocardial subproteomic analysis of a constitutively active Rac1-expressing transgenic mouse with lethal myocardial hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 289: H2325-33. PMID 16155095 DOI: 10.1152/ajpheart.01041.2004  0.2
2005 Fu Q, Garnham CP, Elliott ST, Bovenkamp DE, Van Eyk JE. A robust, streamlined, and reproducible method for proteomic analysis of serum by delipidation, albumin and IgG depletion, and two-dimensional gel electrophoresis. Proteomics. 5: 2656-64. PMID 15924293 DOI: 10.1002/pmic.200402048  1
2005 Graham DR, Garnham CP, Fu Q, Robbins J, Van Eyk JE. Improvements in two-dimensional gel electrophoresis by utilizing a low cost "in-house" neutral pH sodium dodecyl sulfate-polyacrylamide gel electrophoresis system. Proteomics. 5: 2309-14. PMID 15887185 DOI: 10.1002/pmic.200401249  1
2005 Simpson JA, Labugger R, Collier C, Brison RJ, Iscoe S, Van Eyk JE. Fast and slow skeletal troponin I in serum from patients with various skeletal muscle disorders: a pilot study. Clinical Chemistry. 51: 966-72. PMID 15833785 DOI: 10.1373/clinchem.2004.042671  0.16
2005 Neverova I, Van Eyk JE. Role of chromatographic techniques in proteomic analysis. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 815: 51-63. PMID 15652798 DOI: 10.1016/j.jchromb.2004.11.009  0.36
2004 McDonough JL, Van Eyk JE. Developing the next generation of cardiac markers: disease-induced modifications of troponin I. Progress in Cardiovascular Diseases. 47: 207-16. PMID 15736586  0.4
2004 Stanley BA, Gundry RL, Cotter RJ, Van Eyk JE. Heart disease, clinical proteomics and mass spectrometry. Disease Markers. 20: 167-78. PMID 15502250  1
2004 Granger CB, Van Eyk JE, Mockrin SC, Anderson NL. National Heart, Lung, And Blood Institute Clinical Proteomics Working Group report. Circulation. 109: 1697-703. PMID 15078805 DOI: 10.1161/01.CIR.0000121563.47232.2A  1
2003 Li MX, Wang X, Lindhout DA, Buscemi N, Van Eyk JE, Sykes BD. Phosphorylation and mutation of human cardiac troponin I deferentially destabilize the interaction of the functional regions of troponin I with troponin C. Biochemistry. 42: 14460-8. PMID 14661957 DOI: 10.1021/bi035408y  0.24
2003 Dos Remedios CG, Liew CC, Allen PD, Winslow RL, Van Eyk JE, Dunn MJ. Genomics, proteomics and bioinformatics of human heart failure. Journal of Muscle Research and Cell Motility. 24: 251-60. PMID 14620738 DOI: 10.1023/A:1025433721505  1
2003 Buscemi N, Doherty-Kirby A, Sussman MA, Lajoie G, Van Eyk JE. Proteomic analysis of Rac1 transgenic mice displaying dilated cardiomyopathy reveals an increase in creatine kinase M-chain protein abundance. Molecular and Cellular Biochemistry. 251: 145-51. PMID 14575316  0.2
2003 Foster DB, Noguchi T, VanBuren P, Murphy AM, Van Eyk JE. C-terminal truncation of cardiac troponin I causes divergent effects on ATPase and force: implications for the pathophysiology of myocardial stunning. Circulation Research. 93: 917-24. PMID 14551240 DOI: 10.1161/01.RES.0000099889.35340.6F  0.2
2003 Labugger R, Simpson JA, Quick M, Brown HA, Collier CE, Neverova I, Van Eyk JE. Strategy for analysis of cardiac troponins in biological samples with a combination of affinity chromatography and mass spectrometry. Clinical Chemistry. 49: 873-9. PMID 12765982  0.2
2002 Buscemi N, Foster DB, Neverova I, Van Eyk JE. p21-activated kinase increases the calcium sensitivity of rat triton-skinned cardiac muscle fiber bundles via a mechanism potentially involving novel phosphorylation of troponin I. Circulation Research. 91: 509-16. PMID 12242269  0.6
2002 McDonough JL, Neverova I, Van Eyk JE. Proteomic analysis of human biopsy samples by single two-dimensional electrophoresis: Coomassie, silver, mass spectrometry, and Western blotting. Proteomics. 2: 978-87. PMID 12203893 DOI: 10.1002/1615-9861(200208)2:8<978::AID-PROT978>3.0.CO;2-3  0.32
2002 Labugger R, McDonough JL, Neverova I, Van Eyk JE. Solubilization, two-dimensional separation and detection of the cardiac myofilament protein troponin T. Proteomics. 2: 673-8. PMID 12112847 DOI: 10.1002/1615-9861(200206)2:6<673::AID-PROT673>3.0.CO;2-2  0.44
2002 Simpson JA, Labugger R, Hesketh GG, D'Arsigny C, O'Donnell D, Matsumoto N, Collier CP, Iscoe S, Van Eyk JE. Differential detection of skeletal troponin I isoforms in serum of a patient with rhabdomyolysis: markers of muscle injury? Clinical Chemistry. 48: 1112-4. PMID 12089186  0.32
2002 Neverova I, Van Eyk JE. Application of reversed phase high performance liquid chromatography for subproteomic analysis of cardiac muscle. Proteomics. 2: 22-31. PMID 11788988 DOI: 10.1002/1615-9861(200201)2:1<22::AID-PROT22>3.0.CO;2-L  0.4
2001 Arrell DK, Neverova I, Fraser H, Marbán E, Van Eyk JE. Proteomic analysis of pharmacologically preconditioned cardiomyocytes reveals novel phosphorylation of myosin light chain 1. Circulation Research. 89: 480-7. PMID 11557734  0.44
2001 Arrell DK, Neverova I, Van Eyk JE. Cardiovascular proteomics evolution and potential Circulation Research. 88: 763-773. PMID 11325867  0.52
2001 Davis GK, Labugger R, Van Eyk JE, Apple FS. Cardiac troponin T is not detected in western blots of diseased renal tissue Clinical Chemistry. 47: 782-783. PMID 11274043  0.24
2001 McDonough JL, Labugger R, Pickett W, Tse MY, MacKenzie S, Pang SC, Atar D, Ropchan G, Van Eyk JE. Cardiac troponin I is modified in the myocardium of bypass patients. Circulation. 103: 58-64. PMID 11136686  0.24
2000 Lehman W, Hatch V, Korman V, Rosol M, Thomas L, Maytum R, Geeves MA, Van Eyk JE, Tobacman LS, Craig R. Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments. Journal of Molecular Biology. 302: 593-606. PMID 10986121 DOI: 10.1006/jmbi.2000.4080  1
2000 Labugger R, Organ L, Collier C, Atar D, Van Eyk JE. Extensive troponin I and T modification detected in serum from patients with acute myocardial infarction. Circulation. 102: 1221-6. PMID 10982534  0.32
2000 Murphy AM, Kögler H, Georgakopoulos D, McDonough JL, Kass DA, Van Eyk JE, Marbán E. Transgenic mouse model of stunned myocardium. Science (New York, N.Y.). 287: 488-91. PMID 10642551 DOI: 10.1126/science.287.5452.488  1
2000 Foster DB, Shen LH, Kelly J, Thibault P, Van Eyk JE, Mak AS. Phosphorylation of caldesmon by p21-activated kinase. Implications for the Ca2+ sensitivity of smooth muscle contraction Journal of Biological Chemistry. 275: 1959-1965. PMID 10636898 DOI: 10.1074/jbc.275.3.1959  0.16
1999 Foster DB, Van Eyk JE. In search of the proteins that cause myocardial stunning Circulation Research. 85: 470-472. PMID 10473676  0.92
1999 McDonough JL, Arrell DK, Van Eyk JE. Troponin I degradation and covalent complex formation accompanies myocardial ischemia/reperfusion injury Circulation Research. 84: 9-20. PMID 9915770  0.68
1998 Van Eyk JE, Arrell DK, Foster DB, Strauss JD, Heinonen TY, Furmaniak-Kazmierczak E, Côté GP, Mak AS. Different molecular mechanisms for Rho family GTPase-dependent, Ca2+-independent contraction of smooth muscle. The Journal of Biological Chemistry. 273: 23433-9. PMID 9722579 DOI: 10.1074/jbc.273.36.23433  0.04
1998 Van Eyk JE, Powers F, Law W, Larue C, Hodges RS, Solaro RJ. Breakdown and release of myofilament proteins during ischemia and ischemia/reperfusion in rat hearts: identification of degradation products and effects on the pCa-force relation. Circulation Research. 82: 261-71. PMID 9468197  0.4
1997 Tripet B, Van Eyk JE, Hodges RS. Mapping of a second actin-tropomyosin and a second troponin C binding site within the C terminus of troponin I, and their importance in the Ca2+-dependent regulation of muscle contraction. Journal of Molecular Biology. 271: 728-50. PMID 9299323 DOI: 10.1006/jmbi.1997.1200  0.88
1997 Van Eyk JE, Thomas LT, Tripet B, Wiesner RJ, Pearlstone JR, Farah CS, Reinach FC, Hodges RS. Distinct regions of troponin I regulate Ca2+-dependent activation and Ca2+ sensitivity of the acto-S1-TM ATPase activity of the thin filament. The Journal of Biological Chemistry. 272: 10529-37. PMID 9099697  0.32
1996 Strauss JD, Van Eyk JE, Barth Z, Kluwe L, Wiesner RJ, Maéda K, Rüegg JC. Recombinant troponin I substitution and calcium responsiveness in skinned cardiac muscle. PflüGers Archiv : European Journal of Physiology. 431: 853-62. PMID 8927501 DOI: 10.1007/BF02332169  1
1996 Solaro RJ, Van Eyk J. Altered interactions among thin filament proteins modulate cardiac function Journal of Molecular and Cellular Cardiology. 28: 217-230. PMID 8729055 DOI: 10.1006/jmcc.1996.0021  1
1995 Barth Z, Strauss JD, Heyder S, Van Eyk J, Wiesner RJ, Rüegg JC. Ca2+ sensitizing effects of EMD 53998 after troponin replacement in skinned fibres from porcine atria and ventricles. PflüGers Archiv : European Journal of Physiology. 430: 220-9. PMID 7675632 DOI: 10.1007/BF00374653  1
1995 Van Eyk JE, Caday-Malcolm RA, Yu L, Irvin RT, Hodges RS. Anti-peptide monoclonal antibody imaging of a common binding domain involved in muscle regulation Protein Science. 4: 781-790. PMID 7613476  0.44
1993 Van Eyk JE, Strauss JD, Hodges RS, Rüegg JC. A synthetic peptide mimics troponin I function in the calcium-dependent regulation of muscle contraction. Febs Letters. 323: 223-8. PMID 8500614 DOI: 10.1016/0014-5793(93)81344-Y  0.44
1992 Campbell AP, Van Eyk JE, Hodges RS, Sykes BD. Interaction of troponin I and troponin C: use of the two-dimensional transferred nuclear Overhauser effect to determine the structure of a Gly-110 inhibitory troponin I peptide analog when bound to cardiac troponin C. Biochimica Et Biophysica Acta. 1160: 35-54. PMID 1420332  0.44
1992 Strauss JD, Zeugner C, Van Eyk JE, Bletz C, Troschka M, Rüegg JC. Troponin replacement in permeabilized cardiac muscle. Reversible extraction of troponin I by incubation with vanadate. Febs Letters. 310: 229-34. PMID 1397278 DOI: 10.1016/0014-5793(92)81338-M  1
1992 Sönnichsen FD, Van Eyk JE, Hodges RS, Sykes BD. Effect of trifluoroethanol on protein secondary structure: an NMR and CD study using a synthetic actin peptide. Biochemistry. 31: 8790-8. PMID 1390666  0.44
1991 Van Eyk JE, Kay CM, Hodges RS. A comparative study of the interactions of synthetic peptides of the skeletal and cardiac troponin I inhibitory region with skeletal and cardiac troponin C. Biochemistry. 30: 9974-81. PMID 1911788  0.64
1991 Van Eyk JE, Hodges RS. A synthetic peptide of the N-terminus of actin interacts with myosin. Biochemistry. 30: 11676-82. PMID 1836353  1
1989 Rüegg JC, Zeugner C, Van Eyk J, Kay CM, Hodges RS. Inhibition of TnI-TnC interaction and contraction of skinned muscle fibres by the synthetic peptide TnI [104-115]. PflüGers Archiv : European Journal of Physiology. 414: 430-6. PMID 2798040  1
1988 Van Eyk JE, Hodges RS. The biological importance of each amino acid residue of the troponin I inhibitory sequence 104-115 in the interaction with troponin C and tropomyosin-actin. The Journal of Biological Chemistry. 263: 1726-32. PMID 3338991  1
1987 Van Eyk JE, Hodges RS. Calmodulin and troponin C: affinity chromatographic study of divalent cation requirements for troponin I inhibitory peptide (residues 104-115), mastoparan and fluphenazine binding. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 65: 982-8. PMID 3442631  0.96
1986 Cachia PJ, Van Eyk J, Ingraham RH, McCubbin WD, Kay CM, Hodges RS. Calmodulin and troponin C: a comparative study of the interaction of mastoparan and troponin I inhibitory peptide [104-115]. Biochemistry. 25: 3553-62. PMID 2941074  1
1985 Cachia PJ, Van Eyk J, McCubbin WD, Kay CM, Hodges RS. Ion-exchange high-performance liquid chromatographic purification of bovine cardiac and rabbit skeletal muscle troponin subunits. Journal of Chromatography. 343: 315-28. PMID 4066873  1
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