| Year |
Citation |
Score |
| 2022 |
Zieliński M, Blanchet J, Hailemariam S, Berghuis AM. Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa. Plos One. 17: e0269684. PMID 35921328 DOI: 10.1371/journal.pone.0269684 |
0.334 |
|
| 2016 |
Baettig OM, Shi K, Yachnin BJ, Burk DL, Berghuis AM. Comprehensive characterization of ligand-induced plasticity changes in a dimeric enzyme. The Febs Journal. PMID 27333541 DOI: 10.1111/Febs.13788 |
0.316 |
|
| 2014 |
Park J, Lin YS, Tsantrizos YS, Berghuis AM. Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate. Acta Crystallographica. Section F, Structural Biology Communications. 70: 299-304. PMID 24598914 DOI: 10.1107/S2053230X14002106 |
0.323 |
|
| 2014 |
Yachnin B, McEvoy M, MacCuish R, Morley K, Mittermaier A, Lau P, Berghuis A. The Structural Basis for BVMO Substrate Profile and Stereospecificity Acta Crystallographica Section a Foundations and Advances. 70: C485-C485. DOI: 10.1107/S205327331409514X |
0.369 |
|
| 2014 |
Bassenden A, Rodionov D, Sabet-Kassouf N, Haji T, Shi K, Berghuis A. "Structural characterization of aminoglycoside modifying enzyme ANT(2"")-Ia" Acta Crystallographica Section a Foundations and Advances. 70: C702-C702. DOI: 10.1107/S2053273314092973 |
0.303 |
|
| 2014 |
Rodionov D, Marks D, Romero P, Berghuis A. Crystal structure of an alleged mannosylphosphate transferase Ktr6p at 3.06 Å Acta Crystallographica Section a Foundations and Advances. 70: C1671-C1671. DOI: 10.1107/S2053273314083284 |
0.364 |
|
| 2012 |
Park J, Lin YS, De Schutter JW, Tsantrizos YS, Berghuis AM. Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Structural Biology. 12: 32. PMID 23234314 DOI: 10.1186/1472-6807-12-32 |
0.311 |
|
| 2012 |
Yachnin BJ, Sprules T, McEvoy MB, Lau PC, Berghuis AM. The substrate-bound crystal structure of a Baeyer-Villiger monooxygenase exhibits a Criegee-like conformation. Journal of the American Chemical Society. 134: 7788-95. PMID 22506764 DOI: 10.1021/ja211876p |
0.318 |
|
| 2012 |
Shi K, Berghuis AM. Structural basis for dual nucleotide selectivity of aminoglycoside 2''-phosphotransferase IVa provides insight on determinants of nucleotide specificity of aminoglycoside kinases. The Journal of Biological Chemistry. 287: 13094-102. PMID 22371504 DOI: 10.1074/jbc.M112.349670 |
0.324 |
|
| 2011 |
Yachnin BJ, Colin DY, Volpato JP, Ebert M, Pelletier JN, Berghuis AM. Novel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structure Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 67: 1316-1322. PMID 22102224 DOI: 10.1107/S1744309111030417 |
0.344 |
|
| 2011 |
Shi K, Houston DR, Berghuis AM. Crystal structures of antibiotic-bound complexes of aminoglycoside 2''-phosphotransferase IVa highlight the diversity in substrate binding modes among aminoglycoside kinases. Biochemistry. 50: 6237-44. PMID 21678960 DOI: 10.1021/bi200747f |
0.34 |
|
| 2010 |
Fong DH, Lemke CT, Hwang J, Xiong B, Berghuis AM. Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophila. The Journal of Biological Chemistry. 285: 9545-55. PMID 20089863 DOI: 10.1074/jbc.M109.038364 |
0.326 |
|
| 2009 |
Volpato JP, Yachnin BJ, Blanchet J, Guerrero V, Poulin L, Fossati E, Berghuis AM, Pelletier JN. Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance Journal of Biological Chemistry. 284: 20079-20089. PMID 19478082 DOI: 10.1074/Jbc.M109.018010 |
0.309 |
|
| 2007 |
Burk DL, Hwang J, Kwok E, Marrone L, Goodfellow V, Dmitrienko GI, Berghuis AM. Structural studies of the final enzyme in the alpha-aminoadipate pathway-saccharopine dehydrogenase from Saccharomyces cerevisiae. Journal of Molecular Biology. 373: 745-54. PMID 17854830 DOI: 10.1016/J.Jmb.2007.08.044 |
0.329 |
|
| 2006 |
Fong DH, Yim VCN, D'Elia MA, Brown ED, Berghuis AM. Crystal structure of CTP:glycerol-3-phosphate cytidylyltransferase from Staphylococcus aureus: Examination of structural basis for kinetic mechanism Biochimica Et Biophysica Acta - Proteins and Proteomics. 1764: 63-69. PMID 16344011 DOI: 10.1016/j.bbapap.2005.10.015 |
0.357 |
|
| 2005 |
Lemke CT, Hwang J, Xiong B, Cianciotto NP, Berghuis AM. Crystallization and preliminary crystallographic analysis of an aminoglycoside kinase from Legionella pneumophila. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 606-8. PMID 16511108 DOI: 10.1107/S1744309105016301 |
0.346 |
|
| 2005 |
Mirza IA, Nazi I, Korczynska M, Wright GD, Berghuis AM. Crystal structure of homoserine transacetylase from Haemophilus influenzae reveals a new family of α/β-hydrolases Biochemistry. 44: 15768-15773. PMID 16313180 DOI: 10.1021/Bi051951Y |
0.32 |
|
| 2005 |
Burk DL, Xiong B, Breitbach C, Berghuis AM. Structures of aminoglycoside acetyltransferase AAC(6')-Ii in a novel crystal form: structural and normal-mode analyses. Acta Crystallographica. Section D, Biological Crystallography. 61: 1273-9. PMID 16131761 DOI: 10.1107/S0907444905021487 |
0.343 |
|
| 2004 |
Ejim L, Mirza IA, Capone C, Nazi I, Jenkins S, Chee GL, Berghuis AM, Wright GD. New phenolic inhibitors of yeast homoserine dehydrogenase. Bioorganic & Medicinal Chemistry. 12: 3825-30. PMID 15210149 DOI: 10.1016/J.Bmc.2004.05.009 |
0.319 |
|
| 2003 |
Jacques SL, Mirza IA, Ejim L, Koteva K, Hughes DW, Green K, Kinach R, Honek JF, Lai HK, Berghuis AM, Wright GD. Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase. Chemistry & Biology. 10: 989-95. PMID 14583265 DOI: 10.1016/J.Chembiol.2003.09.015 |
0.311 |
|
| 2001 |
Yim VCN, Zolli M, Badurina DS, Rossi L, Brown ED, Berghuis AM. Crystallization and preliminary X-ray diffraction studies of glycerol 3-phosphate cytidylyltransferase from Staphylococcus aureus Acta Crystallographica Section D: Biological Crystallography. 57: 918-920. PMID 11375529 DOI: 10.1107/S0907444901005212 |
0.348 |
|
| 2001 |
Leung AK, Duewel HS, Honek JF, Berghuis AM. Crystal structure of the lytic transglycosylase from bacteriophage lambda in complex with hexa-N-acetylchitohexaose. Biochemistry. 40: 5665-73. PMID 11341831 DOI: 10.1021/Bi0028035 |
0.31 |
|
| 2000 |
DeLaBarre B, Thompson PR, Wright GD, Berghuis AM. Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases. Nature Structural Biology. 7: 238-44. PMID 10700284 DOI: 10.1038/73359 |
0.533 |
|
| 1999 |
Wybenga-Groot LE, Draker Ka, Wright GD, Berghuis AM. Crystal structure of an aminoglycoside 6'-N-acetyltransferase: Defining the GCN5-related N-acetyltransferase superfamily fold Structure. 7: 497-507. PMID 10378269 DOI: 10.1016/S0969-2126(99)80066-5 |
0.309 |
|
| 1998 |
DeLaBarre B, Jacques SL, Pratt CE, Ruth DA, Wright GD, Berghuis AM. Crystallization and preliminary X-ray diffraction studies of homoserine dehydrogenase from Saccharomyces cerevisiae. Acta Crystallographica. Section D, Biological Crystallography. 54: 413-5. PMID 9761913 DOI: 10.1107/S0907444997011967 |
0.519 |
|
| 1996 |
DeLaBarre B, Wright GD, Berghuis AM. Crystallographic studies of homoserine dehydrogenase for the design of novel antifungal agents Acta Crystallographica Section a Foundations of Crystallography. 52: C99-C99. DOI: 10.1107/S0108767396095153 |
0.501 |
|
| 1994 |
Coleman DE, Lee E, Mixon MB, Linder ME, Berghuis AM, Gilman AG, Sprang SR. Crystallization and preliminary crystallographic studies of Gi alpha 1 and mutants of Gi alpha 1 in the GTP and GDP-bound states. Journal of Molecular Biology. 238: 630-4. PMID 8176751 DOI: 10.1006/Jmbi.1994.1320 |
0.315 |
|
| 1993 |
Burk D, Wang Y, Dombroski D, Berghuis AM, Evans SV, Luo Y, Withers SG, Brayer GD. Isolation, crystallization and preliminary diffraction analyses of human pancreatic alpha-amylase. Journal of Molecular Biology. 230: 1084-5. PMID 8478920 DOI: 10.1006/Jmbi.1993.1221 |
0.312 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2006 |
Ishiyama N, Creuzenet C, Miller WL, Demendi M, Anderson EM, Harauz G, Lam JS, Berghuis AM. Structural studies of FlaA1 from Helicobacter pylori reveal the mechanism for inverting 4,6-dehydratase activity. The Journal of Biological Chemistry. 281: 24489-95. PMID 16651261 DOI: 10.1074/Jbc.M602393200 |
0.299 |
|
| 2009 |
Fong DH, Berghuis AM. Structural basis of APH(3')-IIIa-mediated resistance to N1-substituted aminoglycoside antibiotics. Antimicrobial Agents and Chemotherapy. 53: 3049-55. PMID 19433564 DOI: 10.1128/AAC.00062-09 |
0.294 |
|
| 2014 |
Yachnin BJ, McEvoy MB, MacCuish RJ, Morley KL, Lau PC, Berghuis AM. Lactone-bound structures of cyclohexanone monooxygenase provide insight into the stereochemistry of catalysis. Acs Chemical Biology. 9: 2843-51. PMID 25265531 DOI: 10.1021/cb500442e |
0.293 |
|
| 2014 |
Park J, Leung C, Lin Y, De Schutter J, Tsantrizos Y, Berghuis A. Crystal structures of hFPPS in complex with novel anticancer drug leads Acta Crystallographica Section a Foundations and Advances. 70: C712-C712. DOI: 10.1107/S2053273314092870 |
0.29 |
|
| 2004 |
Ishiyama N, Creuzenet C, Lam JS, Berghuis AM. Crystal structure of WbpP, a genuine UDP-N-acetylglucosamine 4-epimerase from Pseudomonas aeruginosa: Substrate specificity in UDP-hexose 4-epimerases Journal of Biological Chemistry. 279: 22635-22642. PMID 15016816 DOI: 10.1074/jbc.M401642200 |
0.289 |
|
| 2013 |
Mirza IA, Burk DL, Xiong B, Iwaki H, Hasegawa Y, Grosse S, Lau PC, Berghuis AM. Structural analysis of a novel cyclohexylamine oxidase from Brevibacterium oxydans IH-35A. Plos One. 8: e60072. PMID 23555888 DOI: 10.1371/Journal.Pone.0060072 |
0.288 |
|
| 2002 |
Fong DH, Berghuis AM. Substrate promiscuity of an aminoglycoside antibiotic resistance enzyme via target mimicry Embo Journal. 21: 2323-2331. PMID 12006485 DOI: 10.1093/emboj/21.10.2323 |
0.288 |
|
| 2011 |
Shi K, Berghuis AM. X-ray crystal structures of aminoglycoside-2′′-phosphotransferase-IVa [APH(2′′)-IVa] Acta Crystallographica Section a Foundations of Crystallography. 67: C306-C306. DOI: 10.1107/S0108767311092312 |
0.284 |
|
| 2012 |
Caldwell SJ, Berghuis AM. Small-angle X-ray scattering analysis of the bifunctional antibiotic resistance enzyme aminoglycoside (6') acetyltransferase-ie/aminoglycoside (2'') phosphotransferase-ia reveals a rigid solution structure. Antimicrobial Agents and Chemotherapy. 56: 1899-906. PMID 22290965 DOI: 10.1128/Aac.06378-11 |
0.282 |
|
| 1999 |
Thompson PR, Schwartzenhauer J, Hughes DW, Berghuis AM, Wright GD. The COOH terminus of aminoglycoside phosphotransferase (3')-IIIa is critical for antibiotic recognition and resistance Journal of Biological Chemistry. 274: 30697-30706. PMID 10521458 DOI: 10.1074/Jbc.274.43.30697 |
0.272 |
|
| 2017 |
Park J, Rodionov D, De Schutter JW, Lin YS, Tsantrizos YS, Berghuis AM. Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase. Plos One. 12: e0186447. PMID 29036218 DOI: 10.1371/Journal.Pone.0186447 |
0.272 |
|
| 2001 |
Burk DL, Hon WC, Leung AK, Berghuis AM. Structural analyses of nucleotide binding to an aminoglycoside phosphotransferase. Biochemistry. 40: 8756-64. PMID 11467935 DOI: 10.1021/bi010504p |
0.271 |
|
| 2017 |
Bacot-Davis VR, Bassenden AV, Sprules T, Berghuis AM. Effect of solvent and protein dynamics in ligand recognition and inhibition of aminoglycoside adenyltransferase 2″-Ia. Protein Science : a Publication of the Protein Society. PMID 28734024 DOI: 10.1002/pro.3224 |
0.265 |
|
| 2014 |
Fong D, Blanchet J, Berghuis A. Determinants of nucleoside specificity of a macrolide phosphotransferase Acta Crystallographica Section a Foundations and Advances. 70: C705-C705. DOI: 10.1107/S2053273314092948 |
0.264 |
|
| 2015 |
Gritzalis D, Park J, Chiu W, Cho H, Lin YS, De Schutter JW, Lacbay CM, Zielinski M, Berghuis AM, Tsantrizos YS. Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase. Bioorganic & Medicinal Chemistry Letters. 25: 1117-23. PMID 25630225 DOI: 10.1016/J.Bmcl.2014.12.089 |
0.262 |
|
| 2017 |
Park J, Zielinski M, Magder A, Tsantrizos YS, Berghuis AM. Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Communications. 8: 14132. PMID 28098152 DOI: 10.1038/ncomms14132 |
0.262 |
|
| 2017 |
Fong DH, Burk DL, Blanchet J, Yan AY, Berghuis AM. Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure (London, England : 1993). PMID 28416110 DOI: 10.1016/J.Str.2017.03.007 |
0.26 |
|
| 2016 |
Caldwell SJ, Huang Y, Berghuis AM. Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2″)-Ia. Structure (London, England : 1993). PMID 27161980 DOI: 10.1016/J.Str.2016.04.002 |
0.257 |
|
| 2018 |
Caldwell SJ, Berghuis AM. Plasticity of aminoglycoside binding to antibiotic kinase APH(2")-Ia. Antimicrobial Agents and Chemotherapy. PMID 29661878 DOI: 10.1128/Aac.00202-18 |
0.256 |
|
| 1996 |
Berghuis AM, Lee E, Raw AS, Gilman AG, Sprang SR. Structure of the GDP-Pi complex of Gly203-->Ala gialpha1: a mimic of the ternary product complex of galpha-catalyzed GTP hydrolysis. Structure (London, England : 1993). 4: 1277-90. PMID 8939752 DOI: 10.1016/S0969-2126(96)00136-0 |
0.255 |
|
| 2004 |
Fortg DH, Berghuis AM. Crystallization and preliminary crystallographic analysis of 3′-aminoglycoside kinase type IIIa complexed with a eukaryotic protein kinase inhibitor, CKI-7 Acta Crystallographica Section D: Biological Crystallography. 60: 1897-1899. PMID 15388945 DOI: 10.1107/S0907444904019390 |
0.255 |
|
| 2002 |
Burk DL, Berghuis AM. Protein kinase inhibitors and antibiotic resistance. Pharmacology & Therapeutics. 93: 283-92. PMID 12191620 DOI: 10.1016/S0163-7258(02)00197-3 |
0.254 |
|
| 2014 |
Caldwell S, Berghuis A. A catalytic switch uncovered in gentamicin resistance kinase APH(2'')-Ia Acta Crystallographica Section a Foundations and Advances. 70: C704-C704. DOI: 10.1107/S205327331409295X |
0.254 |
|
| 2007 |
Korczynska M, Mukhtar TA, Wright GD, Berghuis AM. Structural basis for streptogramin B resistance in Staphylococcus aureus by virginiamycin B lyase. Proceedings of the National Academy of Sciences of the United States of America. 104: 10388-93. PMID 17563376 DOI: 10.1073/Pnas.0701809104 |
0.25 |
|
| 2009 |
Mirza IA, Yachnin BJ, Wang S, Grosse S, Bergeron H, Imura A, Iwaki H, Hasegawa Y, Lau PC, Berghuis AM. Crystal structures of cyclohexanone monooxygenase reveal complex domain movements and a sliding cofactor. Journal of the American Chemical Society. 131: 8848-54. PMID 19385644 DOI: 10.1021/ja9010578 |
0.249 |
|
| 2011 |
Freiburger LA, Baettig OM, Sprules T, Berghuis AM, Auclair K, Mittermaier AK. Competing allosteric mechanisms modulate substrate binding in a dimeric enzyme. Nature Structural & Molecular Biology. 18: 288-94. PMID 21278754 DOI: 10.1038/Nsmb.1978 |
0.247 |
|
| 2020 |
Bassenden AV, Park J, Rodionov D, Berghuis AM. Revisiting the Catalytic Cycle and Kinetic Mechanism of ANT(2″): A Structural and Kinetic Study. Acs Chemical Biology. PMID 32100995 DOI: 10.1021/acschembio.9b00904 |
0.246 |
|
| 2016 |
Bassenden AV, Rodionov D, Shi K, Berghuis AM. Structural Analysis of the Tobramycin and Gentamicin Clinical Resistome Reveals Limitations for Next-generation Aminoglycoside Design. Acs Chemical Biology. PMID 26900880 DOI: 10.1021/acschembio.5b01070 |
0.246 |
|
| 2007 |
Peschard P, Kozlov G, Lin T, Mirza IA, Berghuis AM, Lipkowitz S, Park M, Gehring K. Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b. Molecular Cell. 27: 474-85. PMID 17679095 DOI: 10.1016/J.Molcel.2007.06.023 |
0.243 |
|
| 1997 |
Hon WC, McKay GA, Thompson PR, Sweet RM, Yang DSC, Wright GD, Berghuis AM. Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases Cell. 89: 887-895. PMID 9200607 DOI: 10.1016/S0092-8674(00)80274-3 |
0.24 |
|
| 2005 |
Demendi M, Ishiyama N, Lam JS, Berghuis AM, Creuzenet C. Towards a better understanding of the substrate specificity of the UDP-N-acetylglucosamine C4 epimerase WbpP Biochemical Journal. 389: 173-180. PMID 15752069 DOI: 10.1042/BJ20050263 |
0.234 |
|
| 2020 |
Park J, Pandya VR, Ezekiel SJ, Berghuis AM. Phosphonate and Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthases: A Structure-Guided Perspective. Frontiers in Chemistry. 8: 612728. PMID 33490038 DOI: 10.3389/fchem.2020.612728 |
0.234 |
|
| 2013 |
Mui MZ, Kucharski M, Miron MJ, Hur WS, Berghuis AM, Blanchette P, Branton PE. Identification of the adenovirus E4orf4 protein binding site on the B55α and Cdc55 regulatory subunits of PP2A: Implications for PP2A function, tumor cell killing and viral replication. Plos Pathogens. 9: e1003742. PMID 24244166 DOI: 10.1371/Journal.Ppat.1003742 |
0.234 |
|
| 2014 |
Blanchet J, Fong D, Berghuis A. Study of 2'-macrolide phosphotransferase selectivity for different substrates Acta Crystallographica Section a Foundations and Advances. 70: C703-C703. DOI: 10.1107/S2053273314092961 |
0.234 |
|
| 2003 |
Burk DL, Ghuman N, Wybenga-Groot LE, Berghuis AM. X-ray structure of the AAC(6')-Ii antibiotic resistance enzyme at 1.8 A resolution; examination of oligomeric arrangements in GNAT superfamily members. Protein Science : a Publication of the Protein Society. 12: 426-37. PMID 12592013 DOI: 10.1110/Ps.0233503 |
0.233 |
|
| 2021 |
Bassenden AV, Dumalo L, Park J, Blanchet J, Maiti K, Arya DP, Berghuis AM. Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2') enzymes. Scientific Reports. 11: 11614. PMID 34078922 DOI: 10.1038/s41598-021-89446-3 |
0.233 |
|
| 2014 |
Freiburger L, Miletti T, Zhu S, Baettig O, Berghuis A, Auclair K, Mittermaier A. Substrate-dependent switching of the allosteric binding mechanism of a dimeric enzyme. Nature Chemical Biology. 10: 937-42. PMID 25218742 DOI: 10.1038/Nchembio.1626 |
0.23 |
|
| 2019 |
Toulouse JL, Yachnin BJ, Ruediger EH, Deon D, Gagnon M, Saint-Jacques K, Ebert MCCJC, Forge D, Bastien D, Colin DY, Vanden Eynde JJ, Marinier A, Berghuis AM, Pelletier JN. Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues. Acs Omega. 4: 10056-10069. PMID 31460098 DOI: 10.1021/acsomega.9b00640 |
0.229 |
|
| 2013 |
Shi K, Caldwell SJ, Fong DH, Berghuis AM. Prospects for circumventing aminoglycoside kinase mediated antibiotic resistance. Frontiers in Cellular and Infection Microbiology. 3: 22. PMID 23805415 DOI: 10.3389/Fcimb.2013.00022 |
0.228 |
|
| 2005 |
Bernatchez S, Szymanski CM, Ishiyama N, Li J, Jarrell HC, Lau PC, Berghuis AM, Young NM, Wakarchuk WW. A single bifunctional UDP-GlcNAc/Glc 4-epimerase supports the synthesis of three cell surface glycoconjugates in Campylobacter jejuni. The Journal of Biological Chemistry. 280: 4792-802. PMID 15509570 DOI: 10.1074/jbc.M407767200 |
0.224 |
|
| 2005 |
Fong DH, Burk DL, Berghuis AM. Aminoglycoside kinases and antibiotic resistance Handbook of Experimental Pharmacology. 167: 157-188. DOI: 10.1007/3-540-26670-4-7 |
0.222 |
|
| 2010 |
Lau PCK, Leisch H, Yachnin BJ, Mirza IA, Berghuis AM, Iwaki H, Hasegawa Y. Sustained development in baeyer-villiger biooxidation technology Acs Symposium Series. 1043: 343-372. DOI: 10.1021/bk-2010-1043.ch024 |
0.22 |
|
| 2021 |
Zieliński M, Park J, Sleno B, Berghuis AM. Structural and functional insights into esterase-mediated macrolide resistance. Nature Communications. 12: 1732. PMID 33741980 DOI: 10.1038/s41467-021-22016-3 |
0.219 |
|
| 2002 |
Thompson PR, Boehr DD, Berghuis AM, Wright GD. Mechanism of aminoglycoside antibiotic kinase APH(3')-IIIa: role of the nucleotide positioning loop. Biochemistry. 41: 7001-7. PMID 12033933 DOI: 10.1021/Bi0256680 |
0.206 |
|
| 2011 |
Zhang Z, Mui MZ, Chan F, Roopchand DE, Marcellus RC, Blanchette P, Li S, Berghuis AM, Branton PE. Genetic analysis of B55alpha/Cdc55 protein phosphatase 2A subunits: association with the adenovirus E4orf4 protein. Journal of Virology. 85: 286-95. PMID 21047956 DOI: 10.1128/Jvi.01381-10 |
0.2 |
|
| 2011 |
Yachnin BJ, Lau PCK, Berghuis AM. Unveiling the substrate-bound structure of a Baeyer-Villiger monooxygenase Acta Crystallographica Section a Foundations of Crystallography. 67: C772-C773. DOI: 10.1107/S0108767311080469 |
0.199 |
|
| 2006 |
Gao F, Yan X, Shakya T, Baettig OM, Ait-Mohand-Brunet S, Berghuis AM, Wright GD, Auclair K. Synthesis and structure-activity relationships of truncated bisubstrate inhibitors of aminoglycoside 6'-N-acetyltransferases. Journal of Medicinal Chemistry. 49: 5273-81. PMID 16913716 DOI: 10.1021/Jm060732N |
0.194 |
|
| 1992 |
Sixma TK, Pronk SE, Kalk KH, van Zanten BA, Berghuis AM, Hol WG. Lactose binding to heat-labile enterotoxin revealed by X-ray crystallography. Nature. 355: 561-4. PMID 1741035 DOI: 10.1038/355561A0 |
0.193 |
|
| 2012 |
Lin YS, Park J, De Schutter JW, Huang XF, Berghuis AM, Sebag M, Tsantrizos YS. Design and synthesis of active site inhibitors of the human farnesyl pyrophosphate synthase: apoptosis and inhibition of ERK phosphorylation in multiple myeloma cells. Journal of Medicinal Chemistry. 55: 3201-15. PMID 22390415 DOI: 10.1021/Jm201657X |
0.193 |
|
| 2005 |
Christensen KE, Mirza IA, Berghuis AM, MacKenzie RE. Magnesium and phosphate ions enable NAD binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase Journal of Biological Chemistry. 280: 34316-34323. PMID 16100107 DOI: 10.1074/Jbc.M505210200 |
0.19 |
|
| 2011 |
Fong DH, Xiong B, Hwang J, Berghuis AM. Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor. Plos One. 6: e19589. PMID 21573013 DOI: 10.1371/journal.pone.0019589 |
0.187 |
|
| 1996 |
Hon W-, Wright GD, Yang DS, Berghuis AM. Towards unravelling the structure of an antibiotics-inactivating enzyme – kanamycin kinase Acta Crystallographica Section a Foundations of Crystallography. 52: C204-C204. DOI: 10.1107/S0108767396091179 |
0.186 |
|
| 2021 |
Golkar T, Bassenden AV, Maiti K, Arya DP, Schmeing TM, Berghuis AM. Structural basis for plazomicin antibiotic action and resistance. Communications Biology. 4: 729. PMID 34117352 DOI: 10.1038/s42003-021-02261-4 |
0.186 |
|
| 2017 |
Park J, Leung CY, Matralis AN, Lacbay CM, Tsakos M, Fernandez De Troconiz G, Berghuis AM, Tsantrizos YS. Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. Journal of Medicinal Chemistry. PMID 28208018 DOI: 10.1021/acs.jmedchem.6b01888 |
0.184 |
|
| 1971 |
Van Der Waals JH, Berghuis AMD, De Groot MS. Vibronic interaction in the lower electronic states of benzene II. The hexagonal approximation for the free molecule and the effect of a crystal field Molecular Physics. 21: 497-521. DOI: 10.1080/00268977100101671 |
0.182 |
|
| 2019 |
Feng Y, Park J, Li SG, Boutin R, Viereck P, Schilling M, Berghuis AM, Tsantrizos YS. Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry. PMID 31577901 DOI: 10.1021/acs.jmedchem.9b01104 |
0.181 |
|
| 2006 |
Nascimento M, Zhang WW, Ghosh A, Houston DR, Berghuis AM, Olivier M, Matlashewski G. Identification and characterization of a protein-tyrosine phosphatase in Leishmania: Involvement in virulence Journal of Biological Chemistry. 281: 36257-36268. PMID 17005559 DOI: 10.1074/Jbc.M606256200 |
0.18 |
|
| 2009 |
Matte A, Kozlov G, Trempe JF, Currie MA, Burk D, Jia Z, Gehring K, Ekiel I, Berghuis AM, Cygler M. Preparation and characterization of bacterial protein complexes for structural analysis. Advances in Protein Chemistry and Structural Biology. 76: 1-42. PMID 20663477 DOI: 10.1016/S1876-1623(08)76001-2 |
0.176 |
|
| 1994 |
Berghuis AM, Guillemette JG, Smith M, Brayer GD. Mutation of tyrosine-67 to phenylalanine in cytochrome c significantly alters the local heme environment. Journal of Molecular Biology. 235: 1326-41. PMID 8308895 DOI: 10.1006/Jmbi.1994.1086 |
0.172 |
|
| 2015 |
Bernatchez JA, Paul R, Tchesnokov EP, Ngure M, Beilhartz GL, Berghuis AM, Lavoie R, Li L, Auger A, Melnyk RA, Grobler JA, Miller MD, Hazuda DJ, Hecht SM, Götte M. Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase. The Journal of Biological Chemistry. 290: 1474-84. PMID 25355312 DOI: 10.1074/Jbc.M114.614305 |
0.171 |
|
| 1996 |
Rafferty SP, Guillemette JG, Berghuis AM, Smith M, Brayer GD, Mauk AG. Mechanistic and structural contributions of critical surface and internal residues to cytochrome c electron transfer reactivity. Biochemistry. 35: 10784-92. PMID 8718869 DOI: 10.1021/bi960430v |
0.168 |
|
| 2016 |
Avila EE, Rodriguez OI, Marquez JA, Berghuis AM. An Entamoeba histolytica ADP-ribosyl transferase from the diphtheria toxin family modifies the bacterial elongation factor Tu. Molecular and Biochemical Parasitology. PMID 27234208 DOI: 10.1016/j.molbiopara.2016.05.012 |
0.167 |
|
| 2015 |
Brannon JR, Burk DL, Leclerc JM, Thomassin JL, Portt A, Berghuis AM, Gruenheid S, Le Moual H. Inhibition of outer membrane proteases of the omptin family by aprotinin. Infection and Immunity. 83: 2300-11. PMID 25824836 DOI: 10.1128/Iai.00136-15 |
0.165 |
|
| 2013 |
Leung CY, Park J, De Schutter JW, Sebag M, Berghuis AM, Tsantrizos YS. Thienopyrimidine bisphosphonate (ThPBP) inhibitors of the human farnesyl pyrophosphate synthase: optimization and characterization of the mode of inhibition. Journal of Medicinal Chemistry. 56: 7939-50. PMID 23998921 DOI: 10.1021/jm400946f |
0.158 |
|
| 2005 |
Ishiyama N, Demendi M, Creuzenet C, Lam JS, Berghuis A. Structural studies of FlaA1, a UDP-GlcNAc 4,6-dehydratase Acta Crystallographica Section a Foundations of Crystallography. 61: c189-c189. DOI: 10.1107/S0108767305091968 |
0.157 |
|
| 2023 |
Azzuolo A, Yang Y, Berghuis A, Fodil N, Gros P. Biphosphoglycerate Mutase: A Novel Therapeutic Target for Malaria? Transfusion Medicine Reviews. 37: 150748. PMID 37827586 DOI: 10.1016/j.tmrv.2023.150748 |
0.157 |
|
| 2014 |
Park J, Matralis AN, Berghuis AM, Tsantrizos YS. Human isoprenoid synthase enzymes as therapeutic targets. Frontiers in Chemistry. 2: 50. PMID 25101260 DOI: 10.3389/fchem.2014.00050 |
0.157 |
|
| 1992 |
Berghuis AM, Brayer GD. Oxidation state-dependent conformational changes in cytochrome c Journal of Molecular Biology. 223: 959-976. PMID 1311391 DOI: 10.1016/0022-2836(92)90255-I |
0.15 |
|
| 1994 |
Tong Hua, Berghuis AM, Chen Jie, Luo Yaoguang, Guss JM, Freeman HC, Brayer GD. ASIR: An automatic procedure for determining solvent structure in protein crystallography Journal of Applied Crystallography. 27: 421-426. DOI: 10.1107/S0021889893009926 |
0.148 |
|
| 2016 |
Bacot-Davis VR, Bassenden AV, Berghuis AM. Drug-target networks in aminoglycoside resistance: Hierarchy of priority in structural drug design Medchemcomm. 7: 103-113. DOI: 10.1039/c5md00384a |
0.147 |
|
| 2018 |
Golkar T, Zieliński M, Berghuis AM. Look and Outlook on Enzyme-Mediated Macrolide Resistance. Frontiers in Microbiology. 9: 1942. PMID 30177927 DOI: 10.3389/fmicb.2018.01942 |
0.145 |
|
| 1994 |
Berghuis AM, Guillemette JG, McLendon G, Sherman F, Smith M, Brayer GD. The role of a conserved internal water molecule and its associated hydrogen bond network in cytochrfome c Journal of Molecular Biology. 236: 786-799. PMID 8114094 DOI: 10.1006/Jmbi.1994.1189 |
0.144 |
|
| 2016 |
Yachnin BJ, Lau PC, Berghuis AM. The Role of Conformational Flexibility in Baeyer-Villiger Monooxygenase Catalysis and Structure. Biochimica Et Biophysica Acta. PMID 27570148 DOI: 10.1016/j.bbapap.2016.08.015 |
0.143 |
|
| 1992 |
Langen R, Brayer GD, Berghuis AM, McLendon G, Sherman F, Warshel A. Effect of the Asn52----Ile mutation on the redox potential of yeast cytochrome c. Theory and experiment. Journal of Molecular Biology. 224: 589-600. PMID 1314900 DOI: 10.1016/0022-2836(92)90546-V |
0.138 |
|
| 1994 |
Coleman DE, Berghuis AM, Lee E, Linder ME, Gilman AG, Sprang SR. Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis. Science (New York, N.Y.). 265: 1405-12. PMID 8073283 DOI: 10.1126/Science.8073283 |
0.136 |
|
| 2018 |
Lacbay CM, Waller DD, Park J, Gomez Palou M, Vincent F, Huang XF, Ta V, Berghuis AM, Sebag M, Tsantrizos YS. Unraveling the Prenylation-Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors. Journal of Medicinal Chemistry. PMID 30016091 DOI: 10.1021/acs.jmedchem.8b00886 |
0.135 |
|
| 2014 |
Gobeil SM, Clouthier CM, Park J, Gagné D, Berghuis AM, Doucet N, Pelletier JN. Maintenance of native-like protein dynamics may not be required for engineering functional proteins. Chemistry & Biology. 21: 1330-40. PMID 25200606 DOI: 10.1016/J.Chembiol.2014.07.016 |
0.133 |
|
| 1995 |
Sutton RB, Davletov BA, Berghuis AM, Südhof TC, Sprang SR. Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold. Cell. 80: 929-38. PMID 7697723 DOI: 10.1016/0092-8674(95)90296-1 |
0.133 |
|
| 2002 |
Daigle DM, Rossi L, Berghuis AM, Aravind L, Koonin EV, Brown ED. YjeQ, an essential, conserved, uncharacterized protein from Escherichia coli, is an unusual GTPase with circularly permuted G-motifs and marked burst kinetics. Biochemistry. 41: 11109-17. PMID 12220175 DOI: 10.1021/Bi020355Q |
0.127 |
|
| 1995 |
Mixon MB, Lee E, Coleman DE, Berghuis AM, Gilman AG, Sprang SR. Tertiary and quaternary structural changes in Gi alpha 1 induced by GTP hydrolysis. Science (New York, N.Y.). 270: 954-60. PMID 7481799 DOI: 10.1126/Science.270.5238.954 |
0.124 |
|
| 1998 |
Hunt JF, Mixon MB, Berghuis AM. AUTO_XPL: A Unix shell-script system to sequence X-PLOR refinement runs Journal of Applied Crystallography. 31: 491-495. |
0.112 |
|
| 2008 |
Miller WL, Matewish MJ, McNally DJ, Ishiyama N, Anderson EM, Brewer D, Brisson JR, Berghuis AM, Lam JS. Flagellin glycosylation in Pseudomonas aeruginosa PAK requires the O-antigen biosynthesis enzyme WbpO. The Journal of Biological Chemistry. 283: 3507-18. PMID 18065759 DOI: 10.1074/Jbc.M708894200 |
0.11 |
|
| 2014 |
Lee MJ, Gravelat FN, Cerone RP, Baptista SD, Campoli PV, Choe SI, Kravtsov I, Vinogradov E, Creuzenet C, Liu H, Berghuis AM, Latgé JP, Filler SG, Fontaine T, Sheppard DC. Overlapping and distinct roles of Aspergillus fumigatus UDP-glucose 4-epimerases in galactose metabolism and the synthesis of galactose-containing cell wall polysaccharides. The Journal of Biological Chemistry. 289: 1243-56. PMID 24257745 DOI: 10.1074/jbc.M113.522516 |
0.109 |
|
| 2022 |
Chen OJ, Castellsagué E, Moustafa-Kamal M, Nadaf J, Rivera B, Fahiminiya S, Wang Y, Gamache I, Pacifico C, Jiang L, Carrot-Zhang J, Witkowski L, Berghuis AM, Schoenberger S, Schneider D, et al. Germline Missense Variants in CDC20 Result in Aberrant Mitotic Progression and Familial Cancer. Cancer Research. PMID 35913887 DOI: 10.1158/0008-5472.CAN-21-3956 |
0.107 |
|
| 2014 |
De Schutter JW, Park J, Leung CY, Gormley P, Lin YS, Hu Z, Berghuis AM, Poirier J, Tsantrizos YS. Multistage screening reveals chameleon ligands of the human farnesyl pyrophosphate synthase: implications to drug discovery for neurodegenerative diseases. Journal of Medicinal Chemistry. 57: 5764-76. PMID 24911527 DOI: 10.1021/Jm500629E |
0.106 |
|
| 1996 |
Lett CM, Berghuis AM, Frey HE, Lepock JR, Guillemette JG. The role of a conserved water molecule in the redox-dependent thermal stability of iso-1-cytochrome c. The Journal of Biological Chemistry. 271: 29088-93. PMID 8910563 DOI: 10.1074/jbc.271.46.29088 |
0.104 |
|
| 2017 |
Berghuis AM, Bassenden A. Structural studies of clinical resistomes Acta Crystallographica Section a Foundations and Advances. 73: C632-C632. DOI: 10.1107/S2053273317089410 |
0.102 |
|
| 2016 |
Rivera B, Gayden T, Carrot-Zhang J, Nadaf J, Boshari T, Faury D, Zeinieh M, Blanc R, Burk DL, Fahiminiya S, Bareke E, Schüller U, Monoranu CM, Sträter R, Kerl K, ... ... Berghuis AM, et al. Germline and somatic FGFR1 abnormalities in dysembryoplastic neuroepithelial tumors. Acta Neuropathologica. PMID 26920151 DOI: 10.1007/S00401-016-1549-X |
0.101 |
|
| 2017 |
Rivera B, Di Iorio M, Frankum J, Nadaf J, Fahiminiya S, Arcand SL, Burk DL, Grapton D, Tomiak E, Hastings V, Hamel N, Wagener R, Aleynikova O, Giroux S, Hamdan FF, ... ... Berghuis AM, et al. Functionally null RAD51D missense mutation associates strongly with ovarian carcinoma. Cancer Research. PMID 28646019 DOI: 10.1158/0008-5472.Can-17-0190 |
0.099 |
|
| 2008 |
Xiong B, Burk DL, Shen J, Luo X, Liu H, Shen J, Berghuis AM. The type IA topoisomerase catalytic cycle: A normal mode analysis and molecular dynamics simulation. Proteins. 71: 1984-94. PMID 18186484 DOI: 10.1002/Prot.21876 |
0.099 |
|
| 1991 |
Hickey DR, Berghuis AM, Lafond G, Jaeger JA, Cardillo TS, McLendon D, Das G, Sherman F, Brayer GD, McLendon G. Enhanced thermodynamic stabilities of yeast Iso-1-cytochromes C with amino acid replacements at positions 52 and 102 Journal of Biological Chemistry. 266: 11686-11694. PMID 1646814 |
0.099 |
|
| 2005 |
Korczynska M, Berghuis AM. Structural studies of an antibiotic resistance factor Acta Crystallographica Section a Foundations of Crystallography. 61: c181-c181. DOI: 10.1107/S0108767305092275 |
0.095 |
|
| 2022 |
Berghuis AM, Tichauer RH, de Jong LMA, Sokolovskii I, Bai P, Ramezani M, Murai S, Groenhof G, Gómez Rivas J. Controlling Exciton Propagation in Organic Crystals through Strong Coupling to Plasmonic Nanoparticle Arrays. Acs Photonics. 9: 2263-2272. PMID 35880071 DOI: 10.1021/acsphotonics.2c00007 |
0.095 |
|
| 2020 |
Ilie A, Boucher A, Park J, Berghuis AM, McKinney RA, Orlowski J. Assorted dysfunctions of endosomal alkali cation/proton exchanger SLC9A6 variants linked to Christianson syndrome. The Journal of Biological Chemistry. PMID 32277048 DOI: 10.1074/Jbc.Ra120.012614 |
0.094 |
|
| 2022 |
Markarian NM, Galli G, Patel D, Hemmings M, Nagpal P, Berghuis AM, Abrahamyan L, Vidal SM. Identifying Markers of Emerging SARS-CoV-2 Variants in Patients With Secondary Immunodeficiency. Frontiers in Microbiology. 13: 933983. PMID 35847101 DOI: 10.3389/fmicb.2022.933983 |
0.092 |
|
| 1998 |
Wright GD, Berghuis AM, Mobashery S. Aminoglycoside antibiotics: Structures, functions, and resistance Advances in Experimental Medicine and Biology. 456: 27-69. PMID 10549363 |
0.09 |
|
| 2009 |
Rodionov D, Romero PA, Berghuis AM, Herscovics A. Expression and purification of recombinant M-Pol I from Saccharomyces cerevisiae with alpha-1,6 mannosylpolymerase activity. Protein Expression and Purification. 66: 1-6. PMID 19249370 DOI: 10.1016/J.Pep.2009.02.013 |
0.088 |
|
| 2019 |
Gobeil SMC, Ebert MCCJC, Park J, Gagné D, Doucet N, Berghuis AM, Pleiss J, Pelletier JN. The Structural Dynamics of Engineered β-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function. Scientific Reports. 9: 6656. PMID 31040324 DOI: 10.1038/S41598-019-42866-8 |
0.084 |
|
| 2010 |
Gomez MA, Alisaraie L, Shio MT, Berghuis AM, Lebrun C, Gautier-Luneau I, Olivier M. Protein tyrosine phosphatases are regulated by mononuclear iron dicitrate. The Journal of Biological Chemistry. 285: 24620-8. PMID 20519508 DOI: 10.1074/Jbc.M110.107037 |
0.082 |
|
| 2013 |
Cheung YH, Gayden T, Campeau PM, LeDuc CA, Russo D, Nguyen VH, Guo J, Qi M, Guan Y, Albrecht S, Moroz B, Eldin KW, Lu JT, Schwartzentruber J, Malkin D, ... Berghuis AM, et al. A recurrent PDGFRB mutation causes familial infantile myofibromatosis. American Journal of Human Genetics. 92: 996-1000. PMID 23731537 DOI: 10.1016/J.Ajhg.2013.04.026 |
0.082 |
|
| 2018 |
Gomes CC, Gayden T, Bajic A, Harraz OF, Pratt J, Nikbakht H, Bareke E, Diniz MG, Castro WH, St-Onge P, Sinnett D, Han H, Rivera B, Mikael LG, De Jay N, ... ... Berghuis AM, et al. TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw. Nature Communications. 9: 4572. PMID 30385747 DOI: 10.1038/S41467-018-06690-4 |
0.077 |
|
| 2019 |
Kennedy JM, Georges A, Bassenden AV, Vidal SM, Berghuis AM, Taniuchi I, Majewski J, Lathrop M, Behr MA, Langlais D, Gros P. ZBTB7B (ThPOK) IS REQUIRED FOR PATHOGENESIS OF CEREBRAL MALARIA AND PROTECTION AGAINST PULMONARY TUBERCULOSIS. Infection and Immunity. PMID 31792077 DOI: 10.1128/Iai.00845-19 |
0.074 |
|
| 2018 |
Ilie A, Gao AYL, Boucher A, Park J, Berghuis AM, Hoffer MJV, Hilhorst-Hofstee Y, Anne McKinney R, Orlowski J. A potential gain-of-function variant of SLC9A6 leads to endosomal alkalinization and neuronal atrophy associated with Christianson Syndrome. Neurobiology of Disease. PMID 30296617 DOI: 10.1016/j.nbd.2018.10.002 |
0.074 |
|
| 2020 |
Chen CCL, Deshmukh S, Jessa S, Hadjadj D, Lisi V, Andrade AF, Faury D, Jawhar W, Dali R, Suzuki H, Pathania M, A D, Dubois F, Woodward E, Hébert S, ... ... Berghuis AM, et al. Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis. Cell. PMID 33259802 DOI: 10.1016/j.cell.2020.11.012 |
0.073 |
|
| 2021 |
Berghuis AM, Raziman TV, Halpin A, Wang S, Curto AG, Rivas JG. Effective Negative Diffusion of Singlet Excitons in Organic Semiconductors. The Journal of Physical Chemistry Letters. 1360-1366. PMID 33507078 DOI: 10.1021/acs.jpclett.0c03171 |
0.072 |
|
| 2023 |
Gayden T, Crevier-Sorbo G, Jawhar W, Saint-Martin C, Eveleigh R, Gilardino MS, Anastasio N, Trakadis Y, Bassenden AV, Berghuis AM, Jabado N, Dudley RWR. Association of novel mutation in TRPV4 with familial nonsyndromic craniosynostosis with complete penetrance and variable expressivity. Journal of Neurosurgery. Pediatrics. 1-9. PMID 36905673 DOI: 10.3171/2023.1.PEDS22287 |
0.07 |
|
| 2014 |
Salem S, Langlais D, Lefebvre F, Bourque G, Bigley V, Haniffa M, Casanova JL, Burk D, Berghuis A, Butler KM, Leahy TR, Hambleton S, Gros P. Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation. Blood. 124: 1894-904. PMID 25122610 DOI: 10.1182/Blood-2014-04-570879 |
0.069 |
|
| 2017 |
Berghuis AM, Koffijberg H, Prakash J, Terstappen LW, IJzerman MJ. Detecting Blood-Based Biomarkers in Metastatic Breast Cancer: A Systematic Review of Their Current Status and Clinical Utility. International Journal of Molecular Sciences. 18. PMID 28208771 DOI: 10.3390/ijms18020363 |
0.067 |
|
| 2020 |
Xu G, van Bruggen R, Gualtieri CO, Moradin N, Fois A, Vallerand D, De Sa Tavares Russo M, Bassenden A, Lu W, Tam M, Lesage S, Girouard H, Avizonis DZ, Deblois G, Prchal JT, ... ... Berghuis A, et al. Bisphosphoglycerate Mutase Deficiency Protects against Cerebral Malaria and Severe Malaria-Induced Anemia. Cell Reports. 32: 108170. PMID 32966787 DOI: 10.1016/j.celrep.2020.108170 |
0.067 |
|
| 2012 |
Keller RJ, Peterken CJ, Berghuis AP. Design and assessment of weirs for fish passage under drowned conditions Ecological Engineering. 48: 61-69. DOI: 10.1016/j.ecoleng.2011.06.037 |
0.066 |
|
| 2021 |
Ragamin A, Gomes CC, Bindels-de Heus K, Sandoval R, Bassenden AV, Dib L, Kok F, Alves J, Mathijssen I, Medici-Van den Herik E, Eveleigh R, Gayden T, Pullens B, Berghuis A, van Slegtenhorst M, et al. De novo Leu619Pro variant causes a new channelopathy characterised by giant cell lesions of the jaws and skull, skeletal abnormalities and polyneuropathy. Journal of Medical Genetics. PMID 33685999 DOI: 10.1136/jmedgenet-2020-107427 |
0.066 |
|
| 2007 |
Stuart IG, Berghuis AP, Long PE, Mallen-Cooper M. Do fish locks have potential in tropical rivers? River Research and Applications. 23: 269-286. DOI: 10.1002/rra.979 |
0.066 |
|
| 2020 |
van Son MHC, Berghuis AM, Eisenreich F, de Waal B, Vantomme G, Goméz Rivas J, Meijer EW. Highly Ordered 2D-Assemblies of Phase-Segregated Block Molecules for Upconverted Linearly Polarized Emission. Advanced Materials (Deerfield Beach, Fla.). e2004775. PMID 33118197 DOI: 10.1002/adma.202004775 |
0.062 |
|
| 2008 |
Gomez MA, Contreras I, Alisaraie L, Halle M, Tremblay ML, Berghuis AM, McMaster RW, Olivier M. 249 Leishmania promastigotes modulate macrophage signal transduction by targeting host protein tyrosine phosphatases in a GP63-dependent manner Cytokine. 43: 298-299. DOI: 10.1016/J.Cyto.2008.07.314 |
0.062 |
|
| 2023 |
van Strien N, Niskanen J, Berghuis A, Pöhler H, Rautiainen S. Production of 2,5-furandicarboxylic acid methyl esters from pectin-based aldaric acid: From laboratory to bench scale. Chemsuschem. e202300732. PMID 37632359 DOI: 10.1002/cssc.202300732 |
0.062 |
|
| 2018 |
Zeune LL, de Wit S, Berghuis AMS, IJzerman MJ, Terstappen LWMM, Brune C. How to Agree on a CTC: Evaluating the Consensus in Circulating Tumor Cell Scoring. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 30246927 DOI: 10.1002/cyto.a.23576 |
0.062 |
|
| 2011 |
Hambleton S, Salem S, Bustamante J, Bigley V, Boisson-Dupuis S, Azevedo J, Fortin A, Haniffa M, Ceron-Gutierrez L, Bacon CM, Menon G, Trouillet C, McDonald D, Carey P, Ginhoux F, ... ... Berghuis A, et al. IRF8 mutations and human dendritic-cell immunodeficiency. The New England Journal of Medicine. 365: 127-38. PMID 21524210 DOI: 10.1056/Nejmoa1100066 |
0.059 |
|
| 2023 |
van Son MHC, Berghuis AM, de Waal BFM, Wenzel FA, Kreger K, Schmidt HW, Rivas JG, Vantomme G, Meijer EW. Highly Ordered Supramolecular Materials of Phase-Separated Block Molecules for Long-Range Exciton Transport. Advanced Materials (Deerfield Beach, Fla.). e2300891. PMID 37002556 DOI: 10.1002/adma.202300891 |
0.059 |
|
| 2017 |
Baenziger J, Kay L, Berghuis A, Tieleman P. Biophysics in Canada. Biochimica Et Biophysica Acta. 1865: 1479-1482. PMID 29031794 DOI: 10.1016/J.Bbapap.2017.10.002 |
0.055 |
|
| 2023 |
Berghuis AM, Castellanos GW, Murai S, Pura JL, Abujetas DR, van Heijst E, Ramezani M, Sánchez-Gil JA, Rivas JG. Room Temperature Exciton-Polariton Condensation in Silicon Metasurfaces Emerging from Bound States in the Continuum. Nano Letters. PMID 37310271 DOI: 10.1021/acs.nanolett.3c01102 |
0.054 |
|
| 2018 |
Berghuis AMS, Koffijberg H, Terstappen LWMM, Sleijfer S, IJzerman MJ. Evidence on the cost of breast cancer drugs is required for rational decision making. Ecancermedicalscience. 12: 825. PMID 29743945 DOI: 10.3332/ecancer.2018.825 |
0.045 |
|
| 2018 |
IJzerman MJ, Berghuis AMS, de Bono J, Terstappen L. Health Economic Impact of Liquid Biopsies in Cancer Management. Expert Review of Pharmacoeconomics & Outcomes Research. PMID 30052095 DOI: 10.1080/14737167.2018.1505505 |
0.045 |
|
| 2019 |
Rivera B, Nadaf J, Fahiminiya S, Apellaniz-Ruiz M, Saskin A, Chong AS, Sharma S, Wagener R, Revil T, Condello V, Harra Z, Hamel N, Sabbaghian N, Muchantef K, Thomas C, ... ... Berghuis A, et al. DGCR8 microprocessor defect characterizes familial multinodular goiter with schwannomatosis. The Journal of Clinical Investigation. PMID 31805011 DOI: 10.1172/Jci130206 |
0.044 |
|
| 2014 |
Klaassen R, Klaassen H, Berghuis A, Berghuis M, Schreven K, Van Der Horst Y, Verkade H, Kearsley L. Migration routes and wintering areas of Dutch Common Swifts Apus apus revealed using geolocators Limosa. 87: 173-181. |
0.043 |
|
| 2005 |
Gao F, Yan X, Baettig OM, Berghuis AM, Auclair K. Regio- and chemoselective 6'-N-derivatization of aminoglycosides: bisubstrate inhibitors as probes to study aminoglycoside 6'-N-acetyltransferases. Angewandte Chemie (International Ed. in English). 44: 6859-62. PMID 16206301 DOI: 10.1002/Anie.200501399 |
0.042 |
|
| 2024 |
Lavarda G, Berghuis AM, Joseph K, van der Tol JJB, Murai S, Gómez Rivas J, Meijer EW. Tunable emission from H-type supramolecular polymers in optical nanocavities. Chemical Communications (Cambridge, England). PMID 38362956 DOI: 10.1039/d3cc05877h |
0.041 |
|
| 2021 |
Berghuis AY, Pijnenborg JFA, Boltje TJ, Pijnenborg JMA. Sialic acids in gynecological cancer development and progression: Impact on diagnosis and treatment. International Journal of Cancer. 150: 678-687. PMID 34741527 DOI: 10.1002/ijc.33866 |
0.038 |
|
| 2018 |
Kip MMA, van Oers JA, Shajiei A, Beishuizen A, Berghuis AMS, Girbes AR, de Jong E, de Lange DW, Nijsten MWN, IJzerman MJ, Koffijberg H, Kusters R. Cost-effectiveness of procalcitonin testing to guide antibiotic treatment duration in critically ill patients: results from a randomised controlled multicentre trial in the Netherlands. Critical Care (London, England). 22: 293. PMID 30424796 DOI: 10.1186/s13054-018-2234-3 |
0.035 |
|
| 2018 |
de Wit S, Manicone M, Rossi E, Lampignano R, Yang L, Zill B, Rengel-Puertas A, Ouhlen M, Crespo M, Berghuis AMS, Andree KC, Vidotto R, Trapp EK, Tzschaschel M, Colomba E, et al. EpCAM and EpCAM circulating tumor cells in metastatic prostate and breast cancer patients. Oncotarget. 9: 35705-35716. PMID 30479699 DOI: 10.18632/oncotarget.26298 |
0.027 |
|
| 2002 |
Stuart IG, Berghuis AP. Upstream passage of fish through a vertical-slot fishway in an Australian subtropical river Fisheries Management and Ecology. 9: 111-122. DOI: 10.1046/j.1365-2400.2002.00285.x |
0.017 |
|
| 2019 |
Berghuis AMS, van Deurzen CHM, Koffijberg H, Terstappen LWMM, Sleijfer S, IJzerman MJ. Real-world data on discordance between estrogen, progesterone, and HER2 receptor expression on diagnostic tumor biopsy versus tumor resection material. Breast Cancer Research and Treatment. PMID 30756285 DOI: 10.1007/s10549-019-05141-y |
0.01 |
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| 2015 |
Berghuis AM, Koffijberg H, Jzerman MJ. Identifying The Optimal Use Of Ctcs In The Early Staging Phase Of Breast Cancer. Value in Health : the Journal of the International Society For Pharmacoeconomics and Outcomes Research. 18: A348. PMID 26531972 DOI: 10.1016/j.jval.2015.09.624 |
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