Julie Forman-Kay - Publications

Affiliations: 
University of Toronto, Toronto, ON, Canada 
Area:
Biochemistry

128 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Bhowmick A, Brookes DH, Yost S, Dyson HJ, Forman-Kay JD, Gunter D, Head-Gordon M, Hura GL, Pande VS, Wemmer DE, Wright PE, Head-Gordon T. Finding Our Way in the Dark Proteome. Journal of the American Chemical Society. PMID 27387657 DOI: 10.1021/jacs.6b06543  1
2016 Gakhal AK, Jensen TJ, Bozoky Z, Roldan A, Lukacs GL, Forman-Kay J, Riordan JR, Sidhu SS. Development and characterization of synthetic antibodies binding to the cystic fibrosis conductance regulator. Mabs. 0. PMID 27185291 DOI: 10.1080/19420862.2016.1186320  1
2016 Wang TF, Dawson JE, Forman-Kay JD, Kahr WH, Williams S, Chan AK, Kumar R. Molecular structural analysis of a novel and de-novo mutation in the SERPINC1 gene associated with type 1 antithrombin deficiency. British Journal of Haematology. PMID 27098850 DOI: 10.1111/bjh.14090  1
2016 Mazouchi A, Zhang Z, Bahram A, Gomes GN, Lin H, Song J, Chan HS, Forman-Kay JD, Gradinaru CC. Conformations of a Metastable SH3 Domain Characterized by smFRET and an Excluded-Volume Polymer Model. Biophysical Journal. 110: 1510-22. PMID 27074677 DOI: 10.1016/j.bpj.2016.02.033  1
2016 Csizmok V, Follis AV, Kriwacki RW, Forman-Kay JD. Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling. Chemical Reviews. PMID 26922996 DOI: 10.1021/acs.chemrev.5b00548  1
2016 Bah A, Forman-Kay JD. Modulation of Intrinsically Disordered Protein Function by Post-Translational Modifications. The Journal of Biological Chemistry. PMID 26851279 DOI: 10.1074/jbc.R115.695056  1
2015 Hall JD, Wang H, Byrnes LJ, Shanker S, Wang K, Efremov IV, Andrew Chong P, Forman-Kay JD, Aulabaugh AE. Binding screen for cftr correctors finds new chemical matter and yields insights into cf therapeutic strategy. Protein Science : a Publication of the Protein Society. PMID 26444971 DOI: 10.1002/pro.2821  1
2015 Chong PA, Farber PJ, Vernon RM, Hudson RP, Mittermaier AK, Forman-Kay JD. Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization. The Journal of Biological Chemistry. 290: 22862-78. PMID 26149808 DOI: 10.1074/jbc.M115.641134  1
2015 Nott TJ, Petsalaki E, Farber P, Jervis D, Fussner E, Plochowietz A, Craggs TD, Bazett-Jones DP, Pawson T, Forman-Kay JD, Baldwin AJ. Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles. Molecular Cell. 57: 936-47. PMID 25747659 DOI: 10.1016/j.molcel.2015.01.013  1
2015 Bah A, Vernon RM, Siddiqui Z, Krzeminski M, Muhandiram R, Zhao C, Sonenberg N, Kay LE, Forman-Kay JD. Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch. Nature. 519: 106-9. PMID 25533957 DOI: 10.1038/nature13999  1
2015 Kumar R, Dawson JE, Chan AK, Forman-Kay JD, Kahr WH, Williams S. c.1058C>T variant in the SERPINC1 gene is pathogenic for antithrombin deficiency. British Journal of Haematology. 170: 123-5. PMID 25522812 DOI: 10.1111/bjh.13261  1
2014 Kumar R, Chan AK, Dawson JE, Forman-Kay JD, Kahr WH, Williams S. Clinical presentation and molecular basis of congenital antithrombin deficiency in children: a cohort study. British Journal of Haematology. 166: 130-9. PMID 24684277 DOI: 10.1111/bjh.12842  1
2014 Liu B, Chia D, Csizmok V, Farber P, Forman-Kay JD, Gradinaru CC. The effect of intrachain electrostatic repulsion on conformational disorder and dynamics of the Sic1 protein. The Journal of Physical Chemistry. B. 118: 4088-97. PMID 24673507 DOI: 10.1021/jp500776v  1
2014 Varadi M, Kosol S, Lebrun P, Valentini E, Blackledge M, Dunker AK, Felli IC, Forman-Kay JD, Kriwacki RW, Pierattelli R, Sussman J, Svergun DI, Uversky VN, Vendruscolo M, Wishart D, et al. pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins. Nucleic Acids Research. 42: D326-35. PMID 24174539 DOI: 10.1093/nar/gkt960  1
2013 Lukhele S, Bah A, Lin H, Sonenberg N, Forman-Kay JD. Interaction of the eukaryotic initiation factor 4E with 4E-BP2 at a dynamic bipartite interface. Structure (London, England : 1993). 21: 2186-96. PMID 24207126 DOI: 10.1016/j.str.2013.08.030  1
2013 Bozoky Z, Krzeminski M, Muhandiram R, Birtley JR, Al-Zahrani A, Thomas PJ, Frizzell RA, Ford RC, Forman-Kay JD. Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions. Proceedings of the National Academy of Sciences of the United States of America. 110: E4427-36. PMID 24191035 DOI: 10.1073/pnas.1315104110  1
2013 Dawson JE, Farber PJ, Forman-Kay JD. Allosteric coupling between the intracellular coupling helix 4 and regulatory sites of the first nucleotide-binding domain of CFTR. Plos One. 8: e74347. PMID 24058550 DOI: 10.1371/journal.pone.0074347  1
2013 Pocanschi CL, Ehsani S, Mehrabian M, Wille H, Reginold W, Trimble WS, Wang H, Yee A, Arrowsmith CH, Bozóky Z, Kay LE, Forman-Kay JD, Rini JM, Schmitt-Ulms G. The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer. Plos One. 8: e72446. PMID 24039764 DOI: 10.1371/journal.pone.0072446  1
2013 Forman-Kay JD, Mittag T. From sequence and forces to structure, function, and evolution of intrinsically disordered proteins. Structure (London, England : 1993). 21: 1492-9. PMID 24010708 DOI: 10.1016/j.str.2013.08.001  1
2013 Bozoky Z, Krzeminski M, Chong PA, Forman-Kay JD. Structural changes of CFTR R region upon phosphorylation: a plastic platform for intramolecular and intermolecular interactions. The Febs Journal. 280: 4407-16. PMID 23826884 DOI: 10.1111/febs.12422  1
2013 Chong PA, Kota P, Dokholyan NV, Forman-Kay JD. Dynamics intrinsic to cystic fibrosis transmembrane conductance regulator function and stability. Cold Spring Harbor Perspectives in Medicine. 3: a009522. PMID 23457292 DOI: 10.1101/cshperspect.a009522  1
2013 Krzeminski M, Marsh JA, Neale C, Choy WY, Forman-Kay JD. Characterization of disordered proteins with ENSEMBLE. Bioinformatics (Oxford, England). 29: 398-9. PMID 23233655 DOI: 10.1093/bioinformatics/bts701  1
2012 Stollar EJ, Lin H, Davidson AR, Forman-Kay JD. Differential dynamic engagement within 24 SH3 domain: peptide complexes revealed by co-linear chemical shift perturbation analysis. Plos One. 7: e51282. PMID 23251481 DOI: 10.1371/journal.pone.0051282  1
2012 Marsh JA, Teichmann SA, Forman-Kay JD. Probing the diverse landscape of protein flexibility and binding. Current Opinion in Structural Biology. 22: 643-50. PMID 22999889 DOI: 10.1016/j.sbi.2012.08.008  1
2012 Hudson RP, Chong PA, Protasevich II, Vernon R, Noy E, Bihler H, An JL, Kalid O, Sela-Culang I, Mense M, Senderowitz H, Brouillette CG, Forman-Kay JD. Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. 287: 28480-94. PMID 22722932 DOI: 10.1074/jbc.M112.371138  1
2012 Andresen C, Helander S, Lemak A, Farès C, Csizmok V, Carlsson J, Penn LZ, Forman-Kay JD, Arrowsmith CH, Lundström P, Sunnerhagen M. Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding. Nucleic Acids Research. 40: 6353-66. PMID 22457068 DOI: 10.1093/nar/gks263  1
2012 Tang X, Orlicky S, Mittag T, Csizmok V, Pawson T, Forman-Kay JD, Sicheri F, Tyers M. Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCF Cdc4 ubiquitin ligase Proceedings of the National Academy of Sciences of the United States of America. 109: 3287-3292. PMID 22328159 DOI: 10.1073/pnas.1116455109  1
2012 Liang X, Da Paula AC, Bozóky Z, Zhang H, Bertrand CA, Peters KW, Forman-Kay JD, Frizzell RA. Phosphorylation-dependent 14-3-3 protein interactions regulate CFTR biogenesis. Molecular Biology of the Cell. 23: 996-1009. PMID 22278744 DOI: 10.1091/mbc.E11-08-0662  1
2012 Marsh JA, Forman-Kay JD. Ensemble modeling of protein disordered states: experimental restraint contributions and validation. Proteins. 80: 556-72. PMID 22095648 DOI: 10.1002/prot.23220  1
2011 Tammam S, Sampaleanu LM, Koo J, Sundaram P, Ayers M, Chong PA, Forman-Kay JD, Burrows LL, Howell PL. Characterization of the PilN, PilO and PilP type IVa pilus subcomplex. Molecular Microbiology. 82: 1496-514. PMID 22053789 DOI: 10.1111/j.1365-2958.2011.07903.x  1
2011 Kanelis V, Chong PA, Forman-Kay JD. NMR spectroscopy to study the dynamics and interactions of CFTR. Methods in Molecular Biology (Clifton, N.J.). 741: 377-403. PMID 21594798 DOI: 10.1007/978-1-61779-117-8_25  1
2011 Pinheiro AS, Marsh JA, Forman-Kay JD, Peti W. Structural signature of the MYPT1-PP1 interaction. Journal of the American Chemical Society. 133: 73-80. PMID 21142030 DOI: 10.1021/ja107810r  1
2011 Marsh JA, Forman-Kay JD. Experimental and computational characterization of disordered states of proteins Advances in Biomedical Spectroscopy. 3: 77-96. DOI: 10.3233/978-1-60750-695-9-77  1
2010 Chong PA, Lin H, Wrana JL, Forman-Kay JD. Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity. Proceedings of the National Academy of Sciences of the United States of America. 107: 18404-9. PMID 20937913 DOI: 10.1073/pnas.1003023107  1
2010 Marsh JA, Dancheck B, Ragusa MJ, Allaire M, Forman-Kay JD, Peti W. Structural diversity in free and bound states of intrinsically disordered protein phosphatase 1 regulators. Structure (London, England : 1993). 18: 1094-103. PMID 20826336 DOI: 10.1016/j.str.2010.05.015  1
2010 Fatemi N, Korzhnev DM, Velyvis A, Sarkar B, Forman-Kay JD. NMR characterization of copper-binding domains 4-6 of ATP7B . Biochemistry. 49: 8468-77. PMID 20799727 DOI: 10.1021/bi1008535  1
2010 Marsh JA, Forman-Kay JD. Sequence determinants of compaction in intrinsically disordered proteins. Biophysical Journal. 98: 2383-90. PMID 20483348 DOI: 10.1016/j.bpj.2010.02.006  0.32
2010 Mittag T, Marsh J, Grishaev A, Orlicky S, Lin H, Sicheri F, Tyers M, Forman-Kay JD. Structure/Function Implications in a Dynamic Complex of the Intrinsically Disordered Sic1 with the Cdc4 Subunit of an SCF Ubiquitin Ligase Structure. 18: 494-506. PMID 20399186 DOI: 10.1016/j.str.2010.01.020  1
2010 Chevelkov V, Xue Y, Rao DK, Forman-Kay JD, Skrynnikov NR. 15N H/D-SOLEXSY experiment for accurate measurement of amide solvent exchange rates: application to denatured drkN SH3. Journal of Biomolecular Nmr. 46: 227-44. PMID 20195703 DOI: 10.1007/s10858-010-9398-8  1
2010 Ogunjimi AA, Wiesner S, Briant DJ, Varelas X, Sicheri F, Forman-Kay J, Wrana JL. The ubiquitin binding region of the Smurf HECT domain facilitates polyubiquitylation and binding of ubiquitylated substrates. The Journal of Biological Chemistry. 285: 6308-15. PMID 20026602 DOI: 10.1074/jbc.M109.044537  1
2010 Kanelis V, Hudson RP, Thibodeau PH, Thomas PJ, Forman-Kay JD. NMR evidence for differential phosphorylation-dependent interactions in WT and DeltaF508 CFTR. The Embo Journal. 29: 263-77. PMID 19927121 DOI: 10.1038/emboj.2009.329  1
2010 Marsh JA, Forman-Kay JD. Sequence determinants of compaction in intrinsically disordered proteins Biophysical Journal. 98: 2374-2382. DOI: 10.1016/j.bpj.2010.02.012  1
2009 Kahr WH, Savoia A, Pluthero FG, Li L, Christensen H, De Rocco D, Traivaree C, Butchart SE, Curtin J, Stollar EJ, Forman-Kay JD, Blanchette VS. Megakaryocyte and platelet abnormalities in a patient with a W33C mutation in the conserved SH3-like domain of myosin heavy chain IIA. Thrombosis and Haemostasis. 102: 1241-50. PMID 19967157 DOI: 10.1160/TH09-02-0119  1
2009 Murphy JM, Hansen DF, Wiesner S, Muhandiram DR, Borg M, Smith MJ, Sicheri F, Kay LE, Forman-Kay JD, Pawson T. Structural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arrays. Journal of Molecular Biology. 393: 409-24. PMID 19715701 DOI: 10.1016/j.jmb.2009.08.049  1
2009 Stollar EJ, Garcia B, Chong PA, Rath A, Lin H, Forman-Kay JD, Davidson AR. Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p. The Journal of Biological Chemistry. 284: 26918-27. PMID 19590096 DOI: 10.1074/jbc.M109.028431  1
2009 Marsh JA, Forman-Kay JD. Structure and disorder in an unfolded state under nondenaturing conditions from ensemble models consistent with a large number of experimental restraints. Journal of Molecular Biology. 391: 359-74. PMID 19501099 DOI: 10.1016/j.jmb.2009.06.001  1
2009 Forman-Kay JD. The structural basis of CFTR regulation Pediatric Pulmonology. 44: 118-120.  1
2008 Mittag T, Orlicky S, Choy WY, Tang X, Lin H, Sicheri F, Kay LE, Tyers M, Forman-Kay JD. Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor. Proceedings of the National Academy of Sciences of the United States of America. 105: 17772-7. PMID 19008353 DOI: 10.1073/pnas.0809222105  1
2008 Bezsonova I, Bruce MC, Wiesner S, Lin H, Rotin D, Forman-Kay JD. Interactions between the three CIN85 SH3 domains and ubiquitin: implications for CIN85 ubiquitination. Biochemistry. 47: 8937-49. PMID 18680311 DOI: 10.1021/bi800439t  1
2008 Marsh JA, Baker JM, Tollinger M, Forman-Kay JD. Calculation of residual dipolar couplings from disordered state ensembles using local alignment. Journal of the American Chemical Society. 130: 7804-5. PMID 18512919 DOI: 10.1021/ja802220c  1
2008 Dorwart MR, Shcheynikov N, Baker JM, Forman-Kay JD, Muallem S, Thomas PJ. Congenital chloride-losing diarrhea causing mutations in the STAS domain result in misfolding and mistrafficking of SLC26A3. The Journal of Biological Chemistry. 283: 8711-22. PMID 18216024 DOI: 10.1074/jbc.M704328200  1
2008 Bezsonova I, Forman-Kay J, Prosser RS. Molecular oxygen as a paramagnetic NMR probe of protein solvent exposure and topology Concepts in Magnetic Resonance Part a: Bridging Education and Research. 32: 239-253. DOI: 10.1002/cmr.a.20118  1
2007 Wiesner S, Ogunjimi AA, Wang HR, Rotin D, Sicheri F, Wrana JL, Forman-Kay JD. Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain. Cell. 130: 651-62. PMID 17719543 DOI: 10.1016/j.cell.2007.06.050  1
2007 Baker JM, Hudson RP, Kanelis V, Choy WY, Thibodeau PH, Thomas PJ, Forman-Kay JD. CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices. Nature Structural & Molecular Biology. 14: 738-45. PMID 17660831 DOI: 10.1038/nsmb1278  1
2007 Borg M, Mittag T, Pawson T, Tyers M, Forman-Kay JD, Chan HS. Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity. Proceedings of the National Academy of Sciences of the United States of America. 104: 9650-5. PMID 17522259 DOI: 10.1073/pnas.0702580104  1
2007 Marsh JA, Neale C, Jack FE, Choy WY, Lee AY, Crowhurst KA, Forman-Kay JD. Improved structural characterizations of the drkN SH3 domain unfolded state suggest a compact ensemble with native-like and non-native structure. Journal of Molecular Biology. 367: 1494-510. PMID 17320108 DOI: 10.1016/j.jmb.2007.01.038  1
2007 Bezsonova I, Evanics F, Marsh JA, Forman-Kay JD, Prosser RS. Oxygen as a paramagnetic probe of clustering and solvent exposure in folded and unfolded states of an SH3 domain. Journal of the American Chemical Society. 129: 1826-35. PMID 17253684 DOI: 10.1021/ja065173o  1
2007 Mittag T, Forman-Kay JD. Atomic-level characterization of disordered protein ensembles. Current Opinion in Structural Biology. 17: 3-14. PMID 17250999 DOI: 10.1016/j.sbi.2007.01.009  1
2007 Singh VK, Zhou Y, Marsh JA, Uversky VN, Forman-Kay JD, Liu J, Jia Z. Synuclein-gamma targeting peptide inhibitor that enhances sensitivity of breast cancer cells to antimicrotubule drugs. Cancer Research. 67: 626-33. PMID 17234772 DOI: 10.1158/0008-5472.CAN-06-1820  1
2007 Evanics F, Kitevski JL, Bezsonova I, Forman-Kay J, Prosser RS. 19F NMR studies of solvent exposure and peptide binding to an SH3 domain. Biochimica Et Biophysica Acta. 1770: 221-30. PMID 17182189 DOI: 10.1016/j.bbagen.2006.10.017  1
2006 Evanics F, Bezsonova I, Marsh J, Kitevski JL, Forman-Kay JD, Prosser RS. Tryptophan solvent exposure in folded and unfolded states of an SH3 domain by 19F and 1H NMR. Biochemistry. 45: 14120-8. PMID 17115707 DOI: 10.1021/bi061389r  1
2006 Marsh JA, Singh VK, Jia Z, Forman-Kay JD. Sensitivity of secondary structure propensities to sequence differences between alpha- and gamma-synuclein: implications for fibrillation. Protein Science : a Publication of the Protein Society. 15: 2795-804. PMID 17088319 DOI: 10.1110/ps.062465306  1
2006 Wiesner S, Wybenga-Groot LE, Warner N, Lin H, Pawson T, Forman-Kay JD, Sicheri F. A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases. The Embo Journal. 25: 4686-96. PMID 16977320 DOI: 10.1038/sj.emboj.7601315  1
2006 Tollinger M, Neale C, Kay LE, Forman-Kay JD. Characterization of the hydrodynamic properties of the folding transition state of an SH3 domain by magnetization transfer NMR spectroscopy. Biochemistry. 45: 6434-45. PMID 16700554 DOI: 10.1021/bi060268o  1
2006 Chong PA, Lin H, Wrana JL, Forman-Kay JD. An expanded WW domain recognition motif revealed by the interaction between Smad7 and the E3 ubiquitin ligase Smurf2. The Journal of Biological Chemistry. 281: 17069-75. PMID 16641086 DOI: 10.1074/jbc.M601493200  1
2006 Bezsonova I, Korzhnev DM, Prosser RS, Forman-Kay JD, Kay LE. Hydration and packing along the folding pathway of SH3 domains by pressure-dependent NMR. Biochemistry. 45: 4711-9. PMID 16605239 DOI: 10.1021/bi060177r  1
2006 Kanelis V, Bruce MC, Skrynnikov NR, Rotin D, Forman-Kay JD. Structural determinants for high-affinity binding in a Nedd4 WW3* domain-Comm PY motif complex. Structure (London, England : 1993). 14: 543-53. PMID 16531238 DOI: 10.1016/j.str.2005.11.018  1
2005 Bezsonova I, Singer A, Choy WY, Tollinger M, Forman-Kay JD. Structural comparison of the unstable drkN SH3 domain and a stable mutant. Biochemistry. 44: 15550-60. PMID 16300404 DOI: 10.1021/bi0512795  1
2005 Tollinger M, Kay LE, Forman-Kay JD. Measuring pK(a) values in protein folding transition state ensembles by NMR spectroscopy. Journal of the American Chemical Society. 127: 8904-5. PMID 15969539 DOI: 10.1021/ja051942c  1
2005 Finerty PJ, Mittermaier AK, Muhandiram R, Kay LE, Forman-Kay JD. NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain. Biochemistry. 44: 694-703. PMID 15641795 DOI: 10.1021/bi048641k  1
2004 Chong PA, Ozdamar B, Wrana JL, Forman-Kay JD. Disorder in a target for the smad2 mad homology 2 domain and its implications for binding and specificity. The Journal of Biological Chemistry. 279: 40707-14. PMID 15231848 DOI: 10.1074/jbc.M404375200  1
2003 Crowhurst KA, Forman-Kay JD. Aromatic and methyl NOEs highlight hydrophobic clustering in the unfolded state of an SH3 domain. Biochemistry. 42: 8687-95. PMID 12873128 DOI: 10.1021/bi034601p  1
2003 Tollinger M, Crowhurst KA, Kay LE, Forman-Kay JD. Site-specific contributions to the pH dependence of protein stability. Proceedings of the National Academy of Sciences of the United States of America. 100: 4545-50. PMID 12671071 DOI: 10.1073/pnas.0736600100  1
2003 Henry PC, Kanelis V, O'Brien MC, Kim B, Gautschi I, Forman-Kay J, Schild L, Rotin D. Affinity and specificity of interactions between Nedd4 isoforms and the epithelial Na+ channel. The Journal of Biological Chemistry. 278: 20019-28. PMID 12654927 DOI: 10.1074/jbc.M211153200  1
2002 Donaldson LW, Gish G, Pawson T, Kay LE, Forman-Kay JD. Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide. Proceedings of the National Academy of Sciences of the United States of America. 99: 14053-8. PMID 12384576 DOI: 10.1073/pnas.212518799  1
2002 Hwang PM, Choy WY, Lo EI, Chen L, Forman-Kay JD, Raetz CR, Privé GG, Bishop RE, Kay LE. Solution structure and dynamics of the outer membrane enzyme PagP by NMR. Proceedings of the National Academy of Sciences of the United States of America. 99: 13560-5. PMID 12357033 DOI: 10.1073/pnas.212344499  0.32
2002 Finerty PJ, Muhandiram R, Forman-Kay JD. Side-chain dynamics of the SAP SH2 domain correlate with a binding hot spot and a region with conformational plasticity. Journal of Molecular Biology. 322: 605-20. PMID 12225753 DOI: 10.1016/S0022-2836(02)00803-3  1
2002 Crowhurst KA, Tollinger M, Forman-Kay JD. Cooperative interactions and a non-native buried Trp in the unfolded state of an SH3 domain. Journal of Molecular Biology. 322: 163-78. PMID 12215422 DOI: 10.1016/S0022-2836(02)00741-6  1
2002 Tollinger M, Forman-Kay JD, Kay LE. Measurement of side-chain carboxyl pK(a) values of glutamate and aspartate residues in an unfolded protein by multinuclear NMR spectroscopy. Journal of the American Chemical Society. 124: 5714-7. PMID 12010044 DOI: 10.1021/ja020066p  1
2002 Kanelis V, Forman-Kay JD, Kay LE. Multidimensional NMR methods for protein structure determination Iubmb Life. 52: 291-302. PMID 11895078 DOI: 10.1080/152165401317291147  1
2002 Choy WY, Mulder FA, Crowhurst KA, Muhandiram DR, Millett IS, Doniach S, Forman-Kay JD, Kay LE. Distribution of molecular size within an unfolded state ensemble using small-angle X-ray scattering and pulse field gradient NMR techniques. Journal of Molecular Biology. 316: 101-12. PMID 11829506 DOI: 10.1006/jmbi.2001.5328  1
2002 Hwang PM, Li C, Morra M, Lillywhite J, Muhandiram DR, Gertler F, Terhorst C, Kay LE, Pawson T, Forman-Kay JD, Li SC. A 'three-pronged' binding mechanism for the SAP/SH2D1A SH2 domain: Structural basis and relevance to the XLP syndrome Embo Journal. 21: 314-323. PMID 11823424 DOI: 10.1093/emboj/21.3.314  1
2001 Tollinger M, Skrynnikov NR, Mulder FA, Forman-Kay JD, Kay LE. Slow dynamics in folded and unfolded states of an SH3 domain. Journal of the American Chemical Society. 123: 11341-52. PMID 11707108 DOI: 10.1021/ja011300z  1
2001 Donaldson LW, Skrynnikov NR, Choy WY, Muhandiram DR, Sarkar B, Forman-Kay JD, Kay LE. Structural characterization of proteins with an attached ATCUN motif by paramagnetic relaxation enhancement NMR spectroscopy. Journal of the American Chemical Society. 123: 9843-7. PMID 11583547 DOI: 10.1021/ja011241p  1
2001 Choy WY, Forman-Kay JD. Calculation of ensembles of structures representing the unfolded state of an SH3 domain Journal of Molecular Biology. 308: 1011-1032. PMID 11352588 DOI: 10.1006/jmbi.2001.4750  1
2001 Kanelis V, Rotin D, Forman-Kay JD. Solution structure of a Nedd4 WW domain-ENaC peptide complex. Nature Structural Biology. 8: 407-12. PMID 11323714 DOI: 10.1038/87562  1
2001 Mok YK, Elisseeva EL, Davidson AR, Forman-Kay JD. Dramatic stabilization of an SH3 domain by a single substitution: Roles of the folded and unfolded states Journal of Molecular Biology. 307: 913-928. PMID 11273710 DOI: 10.1006/jmbi.2001.4521  1
2000 Mueller GA, Choy WY, Yang D, Forman-Kay JD, Venters RA, Kay LE. Global folds of proteins with low densities of NOEs using residual dipolar couplings: Application to the 370-residue maltodextrin-binding protein Journal of Molecular Biology. 300: 197-212. PMID 10864509 DOI: 10.1006/jmbi.2000.3842  1
2000 Kanelis V, Donaldson L, Muhandiram DR, Rotin D, Forman-Kay JD, Kay LE. Sequential assignment of proline-rich regions in proteins: application to modular binding domain complexes. Journal of Biomolecular Nmr. 16: 253-9. PMID 10805132 DOI: 10.1023/A:1008355012528  1
2000 Kortemme T, Kelly MJ, Kay LE, Forman-Kay J, Serrano L. Similarities between the spectrin SH3 domain denatured state and its folding transition state. Journal of Molecular Biology. 297: 1217-29. PMID 10764585 DOI: 10.1006/jmbi.2000.3618  1
2000 Zwahlen C, Li SC, Kay LE, Pawson T, Forman-Kay JD. Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb Embo Journal. 19: 1505-1515. PMID 10747019 DOI: 10.1093/emboj/19.7.1505  1
1999 Mittermaier A, Kay LE, Forman-Kay JD. Analysis of deuterium relaxation-derived methyl axis order parameters and correlation with local structure. Journal of Biomolecular Nmr. 13: 181-5. PMID 20700817 DOI: 10.1023/A:1008387715167  1
1999 Forman-Kay JD, Pawson T. Diversity in protein recognition by PTB domains Current Opinion in Structural Biology. 9: 690-695. PMID 10607674  1
1999 Li SC, Gish G, Yang D, Coffey AJ, Forman-Kay JD, Ernberg I, Kay LE, Pawson T. Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2DIA Current Biology. 9: 1355-1362. PMID 10607564 DOI: 10.1016/S0960-9822(00)80080-9  1
1999 Forman-Kay JD. The 'dynamics' in the thermodynamics of binding Nature Structural Biology. 6: 1086-1087. PMID 10581541 DOI: 10.1038/70008  1
1999 Maxwell KL, Mittermaier AK, Forman-Kay JD, Davidson AR. A simple in vivo assay for increased protein solubility. Protein Science : a Publication of the Protein Society. 8: 1908-11. PMID 10493593 DOI: 10.1110/ps.8.9.1908  1
1999 Mok YK, Kay CM, Kay LE, Forman-Kay J. NOE data demonstrating a compact unfolded state for an SH3 domain under non-denaturing conditions Journal of Molecular Biology. 289: 619-638. PMID 10356333 DOI: 10.1006/jmbi.1999.2769  1
1999 Yang D, Mok YK, Muhandiram DR, Forman-Kay JD, Kay LE. 1H-13C dipole-dipole cross-correlated spin relaxation as a probe of dynamics in unfolded proteins: Application to the DrkN SH3 domain [14] Journal of the American Chemical Society. 121: 3555-3556. DOI: 10.1021/ja9900914  1
1998 Kanelis V, Farrow NA, Kay LE, Rotin D, Forman-Kay JD. NMR studies of tandem WW domains of Nedd4 in complex with a PY motif-containing region of the epithelial sodium channel. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 76: 341-50. PMID 9923703  1
1998 Li SC, Zwahlen C, Vincent SJF, Jane McGlade C, Kay LE, Pawson T, Forman-Kay JD. Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity Nature Structural Biology. 5: 1075-1083. PMID 9846878 DOI: 10.1038/4185  1
1998 Blanco FJ, Serrano L, Forman-Kay JD. High populations of non-native structures in the denatured state are compatible with the formation of the native folded state Journal of Molecular Biology. 284: 1153-1164. PMID 9837733 DOI: 10.1006/jmbi.1998.2229  1
1998 Kay LE, Muhandiram DR, Wolf G, Shoelson SE, Forman-Kay JD. Correlation between binding and dynamics at SH2 domain interfaces. Nature Structural Biology. 5: 156-63. PMID 9461082 DOI: 10.1038/nsb0298-156  1
1998 Forman-Kay J, Pawson T, Shoelsona S, Kay L. Correlations between structure, dynamics and specific binding in SH2 and PTB domain interactions Faseb Journal. 12.  1
1997 Yang D, Mok YK, Forman-Kay JD, Farrow NA, Kay LE. Contributions to protein entropy and heat capacity from bond vector motions measured by NMR spin relaxation Journal of Molecular Biology. 272: 790-803. PMID 9368658 DOI: 10.1006/jmbi.1997.1285  1
1997 Wang A, Forman-Kay J, Luo Y, Luo M, Chow YH, Plumb J, Friesen JD, Tsui LC, Heng HH, Woolford JL, Hu J. Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome. Human Molecular Genetics. 6: 2117-26. PMID 9328476 DOI: 10.1093/hmg/6.12.2117  1
1997 Singer AU, Forman-Kay JD. pH titration studies of an SH2 domain-phosphopeptide complex: Unusual histidine and phosphate pK(a) values Protein Science. 6: 1910-1919. PMID 9300491  1
1997 Zhang O, Kay LE, Shortle D, Forman-Kay JD. Comprehensive NOE characterization of a partially folded large fragment of staphylococcal nuclease Δ131Δ, using NMR methods with improved resolution Journal of Molecular Biology. 272: 9-20. PMID 9299333 DOI: 10.1006/jmbi.1997.1219  1
1997 Gasmi G, Singer A, Forman-Kay J, Sarkar B. NMR structure of neuromedin C, a neurotransmitter with an amino terminal Cu(II)-, Ni(II)-binding (ATCUN) motif Journal of Peptide Research. 49: 500-509. PMID 9266477  1
1997 Li SC, Songyang Z, Vincent SJ, Zwahlen C, Wiley S, Cantley L, Kay LE, Forman-Kay J, Pawson T. High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif. Proceedings of the National Academy of Sciences of the United States of America. 94: 7204-9. PMID 9207069 DOI: 10.1073/pnas.94.14.7204  1
1997 Zhang O, Forman-Kay JD. NMR studies of unfolded states of an SH3 domain in aqueous solution and denaturing conditions Biochemistry. 36: 3959-3970. PMID 9092826 DOI: 10.1021/bi9627626  1
1997 Zhang O, Forman-Kay JD, Shortle D, Kay LE. Triple-resonance NOESY-based experiments with improved spectral resolution: Applications to structural characterization of unfolded, partially folded and folded proteins Journal of Biomolecular Nmr. 9: 181-200. PMID 9090132 DOI: 10.1023/A:1018658305040  1
1997 Farrow NA, Zhang O, Forman-Kay JD, Kay LE. Characterization of the backbone dynamics of folded and denatured states of an SH3 domain Biochemistry. 36: 2390-2402. PMID 9054544 DOI: 10.1021/bi962548h  1
1996 Li SC, Lai KMV, Gish GD, Parris WE, Van der Geer P, Forman-Kay J, Pawson T. Characterization of the phosphotyrosine-binding domain of the Drosophila Shc protein Journal of Biological Chemistry. 271: 31855-31862. PMID 8943228 DOI: 10.1074/jbc.271.50.31855  1
1996 Kay LE, Muhandiram DR, Farrow NA, Aubin Y, Forman-Kay JD. Correlation between dynamics and high affinity binding in an SH2 domain interaction Biochemistry. 35: 361-368. PMID 8555205 DOI: 10.1021/bi9522312  1
1996 Forman-Kay JD, Ranjith Muhandiram D, Farrow NA, Pascal SM, Yamazaki T, Kay LE. Dynamics in protein complexes: Relationship between motion and specific binding Faseb Journal. 10.  1
1995 Pascal SM, Singer AU, Yamazaki T, Kay LE, Forman-Kay JD. Structural and dynamic characterization of an SH2 domain-phosphopeptide complex by NMR approaches Biochemical Society Transactions. 23: 729-733. PMID 8654826 DOI: 10.1042/bst0230729  1
1995 Zhang O, Forman-Kay JD. Structural characterization of folded and unfolded states of an SH3 domain in equilibrium in aqueous buffer Biochemistry. 34: 6784-6794. PMID 7756310 DOI: 10.1021/bi00020a025  1
1995 Pascal SM, Yamazaki T, Singer AU, Kay LE, Forman-Kay JD. Structural and Dynamic Characterization of the Phosphotyrosine Binding Region of a Src Homology 2 Domain-Phosphopeptide Complex by NMR Relaxation, Proton Exchange, and Chemical Shift Approaches Biochemistry. 34: 11353-11362. PMID 7547863 DOI: 10.1021/bi00036a008  1
1995 Yamazaki T, Pascal SM, Singer AU, Forman-Kay JD, Kay LE. NMR pulse schemes for the sequence-specific assignment of arginine Guanidino 15N and 1H chemical shifts in proteins Journal of the American Chemical Society. 117: 3556-3564.  1
1994 Pascal SM, Singer AU, Gish G, Yamazaki T, Shoelson SE, Pawson T, Kay LE, Forman-Kay JD. Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide. Cell. 77: 461-72. PMID 8181064 DOI: 10.1016/0092-8674(94)90160-0  1
1994 Farrow NA, Zhang O, Forman-Kay JD, Kay LE. A heteronuclear correlation experiment for simultaneous determination of 15N longitudinal decay and chemical exchange rates of systems in slow equilibrium Journal of Biomolecular Nmr. 4: 727-734. PMID 7919956 DOI: 10.1007/BF00404280  1
1994 Zhang O, Kay LE, Olivier JP, Forman-Kay JD. Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques Journal of Biomolecular Nmr. 4: 845-858. PMID 7812156 DOI: 10.1007/BF00398413  1
1993 Yamazaki T, Forman-Kay JD, Kay LE. Two-dimensional NMR experiments for correlating 13Cβ and 1Hδ/ε chemical shifts of aromatic residues in 13C-labeled proteins via scalar couplings Journal of the American Chemical Society. 115: 11054-11055.  1
1992 Forman-Kay JD, Clore GM, Gronenborn AM. Relationship between electrostatics and redox function in human thioredoxin: Characterization of pH titration shifts using two-dimensional homo- and heteronuclear NMR Biochemistry. 31: 3442-3452. PMID 1554726 DOI: 10.1021/bi00128a019  1
1991 Forman-Kay JD, Clore GM, Wingfield PT, Gronenborn AM. High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution Biochemistry®. 30: 2685-2698. PMID 2001356 DOI: 10.1021/bi00224a017  1
1991 Forman-Kay JD, Gronenborn AM, Wingfield PT, Clore GM. Determination of the positions of bound water molecules in the solution structure of reduced human thioredoxin by heteronuclear three-dimensional nuclear magnetic resonance spectroscopy Journal of Molecular Biology. 220: 209-216. PMID 1856855 DOI: 10.1016/0022-2836(91)90004-P  1
1990 Forman-Kay JD, Gronenborn AM, Kay LE, Wingfield PT, Marius Clore G. Studies on the solution conformation of human thioredoxin using heteronuclear15N-1H nuclear magnetic resonance spectroscopy Biochemistry. 29: 1566-1572. PMID 2334715 DOI: 10.1021/bi00458a030  1
1989 Forman-Kay JD, Clore GM, Driscoll PC, Wingfield P, Richards FM, Gronenborn AM. A proton nuclear magnetic resonance assignment and secondary structure determination of recombinant human thioredoxin. Biochemistry. 28: 7088-97. PMID 2684271 DOI: 10.1021/bi00443a045  1
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