| Year |
Citation |
Score |
| 2021 |
Bhansali RS, Rammohan M, Lee P, Laurent AP, Wen Q, Suraneni P, Yip BH, Tsai YC, Jenni S, Bornhauser B, Siret A, Fruit C, Pacheco-Benichou A, Harris E, Besson T, ... ... Crispino JD, et al. DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3. The Journal of Clinical Investigation. 131. PMID 33393494 DOI: 10.1172/JCI135937 |
0.32 |
|
| 2020 |
Schieber M, Marinaccio C, Bolanos LC, Haffey WD, Greis KD, Starczynowski DT, Crispino JD. FBXO11 is a candidate tumor suppressor in the leukemic transformation of myelodysplastic syndrome. Blood Cancer Journal. 10: 98. PMID 33024076 DOI: 10.1038/s41408-020-00362-7 |
0.32 |
|
| 2019 |
Woods B, Chen W, Chiu S, Marinaccio C, Fu C, Gu L, Bulic M, Yang Q, Zouak A, Jia S, Suraneni PK, Xu K, Levine RL, Crispino JD, Wen QJ. Activation of JAK/STAT signaling in megakaryocytes sustains myeloproliferation . Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31217200 DOI: 10.1158/1078-0432.CCR-18-4089 |
0.32 |
|
| 2019 |
Gangat N, Marinaccio C, Swords R, Watts JM, Gurbuxani S, Rademaker A, Fought AJ, Frankfurt O, Altman JK, Wen QJ, Farnoud N, Famulare CA, Patel A, Tapia R, Vallapureddy RR, ... ... Crispino JD, et al. Aurora kinase A inhibition provides clinical benefit, normalizes megakaryocytes and reduces bone marrow fibrosis in patients with myelofibrosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31061068 DOI: 10.1158/1078-0432.CCR-19-1005 |
0.4 |
|
| 2019 |
Lally J, Boasman K, Brown L, Martinelli V, Cappuccio I, Sovani V, Marinaccio C, Crispino JD, Graham C, Rinaldi C. GATA-1 a potential novel biomarker for the differentiation of essential thrombocythaemia and myelofibrosis. Journal of Thrombosis and Haemostasis : Jth. PMID 30889303 DOI: 10.1111/jth.14433 |
0.32 |
|
| 2019 |
Zhao Z, Wang L, Volk AG, Birch NW, Stoltz KL, Bartom ET, Marshall SA, Rendleman EJ, Nestler CM, Shilati J, Schiltz GE, Crispino JD, Shilatifard A. Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia. Genes & Development. 33: 61-74. PMID 30573454 DOI: 10.1101/gad.319830.118 |
0.36 |
|
| 2018 |
Suraneni PK, Corey SJ, Hession MJ, Ishaq R, Awomolo A, Hasan S, Shah C, Liu H, Wickrema A, Debili N, Crispino JD, Eklund EA, Chen Y. Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity. Blood Advances. 2: 3540-3552. PMID 30538113 DOI: 10.1182/bloodadvances.2018021923 |
0.4 |
|
| 2018 |
Fu C, Shi X, Gong Y, Wan Y, Sun Z, Shi H, Wang Z, Marinaccio C, Crispino JD, Xu K. Constitutively Photomorphogenic 1 Reduces the Sensitivity of Chronic Lymphocytic Leukemia Cells to Fludarabine Through Promotion of Ubiquitin-Mediated P53 Degradation. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 50: 2314-2328. PMID 30423551 DOI: 10.1159/000495092 |
0.32 |
|
| 2018 |
Payton M, Cheung HK, Ninniri MSS, Marinaccio C, Wayne WC, Hanestad K, Crispino JD, Juan G, Coxon A. Dual targeting of aurora kinases with AMG 900 exhibits potent preclinical activity against acute myeloid leukemia with distinct post-mitotic outcomes. Molecular Cancer Therapeutics. PMID 30266802 DOI: 10.1158/1535-7163.MCT-18-0186 |
0.32 |
|
| 2018 |
Jin Q, Martinez CA, Arcipowski KM, Zhu Y, Gutiérrez-Díaz BT, Wang KK, Johnson MR, Volk A, Wang F, Wu J, Grove C, Wang H, Sokirniy I, Thomas PM, Goo YA, ... ... Crispino JD, et al. USP7 cooperates with NOTCH1 to drive the oncogenic transcriptional program in T cell leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30224337 DOI: 10.1158/1078-0432.CCR-18-1740 |
0.36 |
|
| 2018 |
Fu C, Wen QJ, Marinaccio C, Ling T, Chen W, Bulic M, Lasho T, Tefferi A, Crispino JD, Xu K. AKT activation is a feature of CALR mutant myeloproliferative neoplasms. Leukemia. PMID 30082822 DOI: 10.1038/s41375-018-0224-8 |
0.32 |
|
| 2018 |
Melo-Cardenas J, Xu Y, Wei J, Tan C, Kong S, Gao B, Montauti E, Kirsammer G, Licht JD, Yu J, Ji P, Crispino JD, Fang D. USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1 dependent mechanism. Blood. PMID 29844011 DOI: 10.1182/blood-2017-10-811760 |
0.44 |
|
| 2018 |
Yang X, Lu B, Sun X, Han C, Fu C, Xu K, Wang M, Li D, Chen Z, Opal P, Wen Q, Crispino JD, Wang QF, Huang Z. ANP32A regulates histone H3 acetylation and promotes leukemogenesis. Leukemia. PMID 29467488 DOI: 10.1038/s41375-018-0010-7 |
0.32 |
|
| 2017 |
Sun X, Lu B, Han C, Qiu W, Jin Q, Li D, Li Q, Yang Q, Wen Q, Opal P, Kini AR, Crispino JD, Huang Z. ANP32A dysregulation contributes to abnormal megakaryopoiesis in acute megakaryoblastic leukemia. Blood Cancer Journal. 7: 661. PMID 29269781 DOI: 10.1038/s41408-017-0031-x |
0.32 |
|
| 2017 |
Gilles L, Arslan AD, Marinaccio C, Wen QJ, Arya P, McNulty M, Yang Q, Zhao JC, Konstantinoff K, Lasho T, Pardanani A, Stein B, Plo I, Sundaravel S, Wickrema A, ... ... Crispino JD, et al. Downregulation of GATA1 drives impaired hematopoiesis in primary myelofibrosis. The Journal of Clinical Investigation. PMID 28240607 DOI: 10.1172/JCI82905 |
0.4 |
|
| 2017 |
Hu D, Gao X, Cao K, Morgan MA, Mas G, Smith ER, Volk AG, Bartom ET, Crispino JD, Di Croce L, Shilatifard A. Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification. Molecular Cell. 65: 460-475.e6. PMID 28157506 DOI: 10.1016/j.molcel.2017.01.013 |
0.36 |
|
| 2017 |
Liang K, Volk AG, Haug JS, Marshall SA, Woodfin AR, Bartom ET, Gilmore JM, Florens L, Washburn MP, Sullivan KD, Espinosa JM, Cannova J, Zhang J, Smith ER, Crispino JD, et al. Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia. Cell. PMID 28065413 DOI: 10.1016/j.cell.2016.12.011 |
0.36 |
|
| 2016 |
Yang Q, Crispino JD, Wen QJ. Kinase signaling and targeted therapy for primary myelofibrosis. Experimental Hematology. PMID 28043820 DOI: 10.1016/j.exphem.2016.12.007 |
0.32 |
|
| 2016 |
Jin Q, Ren Y, Wang M, Suraneni PK, Li D, Crispino JD, Fan J, Huang Z. Novel function of FAXDC2 in megakaryopoiesis. Blood Cancer Journal. 6: e478. PMID 27689744 DOI: 10.1038/bcj.2016.87 |
0.32 |
|
| 2016 |
Fisher JB, Peterson J, Reimer M, Stelloh C, Pulakanti K, Gerbec ZJ, Abel AM, Strouse JM, Strouse C, McNulty M, Malarkannan S, Crispino JD, Milanovich S, Rao S. The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of HoxA7 and HoxA9. Leukemia. PMID 27554164 DOI: 10.1038/leu.2016.240 |
0.92 |
|
| 2016 |
Lee P, Bhansali R, Izraeli S, Hijiya N, Crispino JD. The biology, pathogenesis and clinical aspects of acute lymphoblastic leukemia in children with down syndrome. Leukemia. PMID 27285583 DOI: 10.1038/leu.2016.164 |
0.92 |
|
| 2016 |
Yu C, Yang Q, Chen Y, Wang D, Levine R, Crispino J, Wen Q, Huang Z. Tyrosine 625 plays a key role and cooperates with tyrosine 630 in MPL W515L-induced signaling and myeloproliferative neoplasms. Cell & Bioscience. 6: 34. PMID 27222706 DOI: 10.1186/s13578-016-0097-3 |
0.32 |
|
| 2016 |
McNulty M, Crispino JD. iPSCs Offer a New Look at GATA1-Trisomy 21 Cooperation. Cell Stem Cell. 18: 563-4. PMID 27152438 DOI: 10.1016/j.stem.2016.04.007 |
0.92 |
|
| 2015 |
Jeremy Wen Q, Yang Q, Goldenson B, Malinge S, Lasho T, Schneider RK, Breyfogle LJ, Schultz R, Gilles L, Koppikar P, Abdel-Wahab O, Pardanani A, Stein B, Gurbuxani S, Mullally A, ... ... Crispino JD, et al. Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition. Nature Medicine. PMID 26569382 DOI: 10.1038/nm.3995 |
0.92 |
|
| 2015 |
Blobel G, Bodine D, Brand M, Crispino J, De Bruijn M, Nathan D, Pappayannopoulou T, Porcher C, Strouboulis J, Zon L, Higgs DR, Stamatoyannopoulos G, Engel JD. An International Effort to Cure a Global Health Problem: A report on the 19th Hemoglobin Switching Conference. Experimental Hematology. PMID 26143582 DOI: 10.1016/j.exphem.2015.06.008 |
0.92 |
|
| 2015 |
Volk A, Crispino JD. The role of the chromatin assembly complex (CAF-1) and its p60 subunit (CHAF1b) in homeostasis and disease. Biochimica Et Biophysica Acta. 1849: 979-86. PMID 26066981 DOI: 10.1016/j.bbagrm.2015.05.009 |
0.92 |
|
| 2015 |
Chlon TM, McNulty M, Goldenson B, Rosinski A, Crispino JD. Global transcriptome and chromatin occupancy analysis reveal the short isoform of GATA1 is deficient for erythroid specification and gene expression. Haematologica. 100: 575-84. PMID 25682601 DOI: 10.3324/haematol.2014.112714 |
0.92 |
|
| 2015 |
Goldenson B, Kirsammer G, Stankiewicz MJ, Wen QJ, Crispino JD. Aurora kinase A is required for hematopoiesis but is dispensable for murine megakaryocyte endomitosis and differentiation. Blood. 125: 2141-50. PMID 25670627 DOI: 10.1182/blood-2014-12-615401 |
0.92 |
|
| 2015 |
Sakamoto KM, Grant S, Saleiro D, Crispino JD, Hijiya N, Giles F, Platanias L, Eklund EA. Targeting novel signaling pathways for resistant acute myeloid leukemia. Molecular Genetics and Metabolism. 114: 397-402. PMID 25533111 DOI: 10.1016/j.ymgme.2014.11.017 |
0.92 |
|
| 2015 |
Shaham L, Vendramini E, Ge Y, Goren Y, Birger Y, Tijssen MR, McNulty M, Geron I, Schwartzman O, Goldberg L, Chou ST, Pitman H, Weiss MJ, Michaeli S, Sredni B, ... ... Crispino JD, et al. MicroRNA-486-5p is an erythroid oncomiR of the myeloid leukemias of Down syndrome. Blood. 125: 1292-301. PMID 25533034 DOI: 10.1182/blood-2014-06-581892 |
0.92 |
|
| 2014 |
Lane AA, Chapuy B, Lin CY, Tivey T, Li H, Townsend EC, van Bodegom D, Day TA, Wu SC, Liu H, Yoda A, Alexe G, Schinzel AC, Sullivan TJ, Malinge S, ... ... Crispino JD, et al. Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation. Nature Genetics. 46: 618-23. PMID 24747640 DOI: 10.1038/ng.2949 |
0.92 |
|
| 2014 |
Crispino JD, Weiss MJ. Erythro-megakaryocytic transcription factors associated with hereditary anemia. Blood. 123: 3080-8. PMID 24652993 DOI: 10.1182/blood-2014-01-453167 |
0.92 |
|
| 2014 |
Liu L, Wen Q, Gong R, Gilles L, Stankiewicz MJ, Li W, Guo M, Li L, Sun X, Li W, Crispino JD, Huang Z. PSTPIP2 dysregulation contributes to aberrant terminal differentiation in GATA-1-deficient megakaryocytes by activating LYN. Cell Death & Disease. 5: e988. PMID 24407241 DOI: 10.1038/cddis.2013.512 |
0.92 |
|
| 2014 |
Gang EJ, Hsieh YT, Pham J, Zhao Y, Nguyen C, Huantes S, Park E, Naing K, Klemm L, Swaminathan S, Conway EM, Pelus LM, Crispino J, Mullighan CG, McMillan M, et al. Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia. Oncogene. 33: 2169-78. PMID 23728349 DOI: 10.1038/onc.2013.169 |
0.92 |
|
| 2014 |
Goldenson B, Crispino JD. The aurora kinases in cell cycle and leukemia Oncogene. DOI: 10.1038/onc.2014.14 |
0.92 |
|
| 2013 |
Malinge S, Chlon T, Doré LC, Ketterling RP, Tallman MS, Paietta E, Gamis AS, Taub JW, Chou ST, Weiss MJ, Crispino JD, Figueroa ME. Development of acute megakaryoblastic leukemia in Down syndrome is associated with sequential epigenetic changes. Blood. 122: e33-43. PMID 23980066 DOI: 10.1182/blood-2013-05-503011 |
0.92 |
|
| 2013 |
Krause DS, Crispino JD. Molecular pathways: induction of polyploidy as a novel differentiation therapy for leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 6084-8. PMID 23963861 DOI: 10.1158/1078-0432.CCR-12-2604 |
0.92 |
|
| 2013 |
Khan I, Huang Z, Wen Q, Stankiewicz MJ, Gilles L, Goldenson B, Schultz R, Diebold L, Gurbuxani S, Finke CM, Lasho TL, Koppikar P, Pardanani A, Stein B, Altman JK, ... ... Crispino JD, et al. AKT is a therapeutic target in myeloproliferative neoplasms. Leukemia. 27: 1882-90. PMID 23748344 DOI: 10.1038/leu.2013.167 |
0.92 |
|
| 2013 |
Lasho T, Johnson SH, Smith DI, Crispino JD, Pardanani A, Vasmatzis G, Tefferi A. Identification of submicroscopic genetic changes and precise breakpoint mapping in myelofibrosis using high resolution mate-pair sequencing. American Journal of Hematology. 88: 741-6. PMID 23733509 DOI: 10.1002/ajh.23495 |
0.92 |
|
| 2013 |
Birger Y, Goldberg L, Chlon TM, Goldenson B, Muler I, Schiby G, Jacob-Hirsch J, Rechavi G, Crispino JD, Izraeli S. Perturbation of fetal hematopoiesis in a mouse model of Down syndrome's transient myeloproliferative disorder. Blood. 122: 988-98. PMID 23719302 DOI: 10.1182/blood-2012-10-460998 |
0.92 |
|
| 2013 |
Stankiewicz MJ, Crispino JD. AKT collaborates with ERG and Gata1s to dysregulate megakaryopoiesis and promote AMKL Leukemia. 27: 1339-1347. PMID 23380710 DOI: 10.1038/leu.2013.33 |
0.92 |
|
| 2013 |
Malinge S, Thiollier C, Chlon TM, Doré LC, Diebold L, Bluteau O, Mabialah V, Vainchenker W, Dessen P, Winandy S, Mercher T, Crispino JD. Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling. Blood. 121: 2440-51. PMID 23335373 DOI: 10.1182/blood-2012-08-450627 |
0.92 |
|
| 2012 |
Thiollier C, Pflumio F, Ballerini P, Crispino JD, Bernard O, Mercher T. [Novel ETO2-GLIS2 fusion and therapeutic strategy in acute megakaryoblastic leukemia]. MéDecine Sciences : M/S. 28: 1013-6. PMID 23171910 DOI: 10.1051/medsci/20122811025 |
0.92 |
|
| 2012 |
Crispino JD, Le Beau MM. BMP meets AML: induction of BMP signaling by a novel fusion gene promotes pediatric acute leukemia. Cancer Cell. 22: 567-8. PMID 23153530 DOI: 10.1016/j.ccr.2012.10.008 |
0.92 |
|
| 2012 |
Chlon TM, Crispino JD. Combinatorial regulation of tissue specification by GATA and FOG factors. Development (Cambridge, England). 139: 3905-16. PMID 23048181 DOI: 10.1242/dev.080440 |
0.92 |
|
| 2012 |
Thiollier C, Lopez CK, Gerby B, Ignacimouttou C, Poglio S, Duffourd Y, Guégan J, Rivera-Munoz P, Bluteau O, Mabialah V, Diop M, Wen Q, Petit A, Bauchet AL, Reinhardt D, ... ... Crispino JD, et al. Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models. The Journal of Experimental Medicine. 209: 2017-31. PMID 23045605 DOI: 10.1084/jem.20121343 |
0.92 |
|
| 2012 |
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, ... ... Crispino JD, et al. Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. Cell. 150: 575-89. PMID 22863010 DOI: 10.1016/j.cell.2012.06.032 |
0.92 |
|
| 2012 |
Crispino JD. JAKing up AML1-ETO. Blood. 120: 703-4. PMID 22835885 DOI: 10.1182/blood-2012-05-413104 |
0.92 |
|
| 2012 |
Chlon TM, Doré LC, Crispino JD. Cofactor-mediated restriction of GATA-1 chromatin occupancy coordinates lineage-specific gene expression. Molecular Cell. 47: 608-21. PMID 22771118 DOI: 10.1016/j.molcel.2012.05.051 |
0.92 |
|
| 2012 |
Keerthivasan G, Liu H, Gump JM, Dowdy SF, Wickrema A, Crispino JD. A novel role for survivin in erythroblast enucleation. Haematologica. 97: 1471-9. PMID 22491741 DOI: 10.3324/haematol.2011.061093 |
0.92 |
|
| 2012 |
Abdel-Wahab O, Pardanani A, Bernard OA, Finazzi G, Crispino JD, Gisslinger H, Kralovics R, Odenike O, Bhalla K, Gupta V, Barosi G, Gotlib J, Guglielmelli P, Kiladjian JJ, Noel P, et al. Unraveling the genetic underpinnings of myeloproliferative neoplasms and understanding their effect on disease course and response to therapy: proceedings from the 6th International Post-ASH Symposium. American Journal of Hematology. 87: 562-8. PMID 22460584 DOI: 10.1002/ajh.23169 |
0.92 |
|
| 2012 |
Doré LC, Chlon TM, Brown CD, White KP, Crispino JD. Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis. Blood. 119: 3724-33. PMID 22383799 DOI: 10.1182/blood-2011-09-380634 |
0.92 |
|
| 2012 |
Malinge S, Bliss-Moreau M, Kirsammer G, Diebold L, Chlon T, Gurbuxani S, Crispino JD. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome. The Journal of Clinical Investigation. 122: 948-62. PMID 22354171 DOI: 10.1172/JCI60455 |
0.92 |
|
| 2012 |
Galat V, Malchenko S, Galat Y, Ishkin A, Nikolsky Y, Kosak ST, Soares BM, Iannaccone P, Crispino JD, Hendrix MJ. A model of early human embryonic stem cell differentiation reveals inter- and intracellular changes on transition to squamous epithelium. Stem Cells and Development. 21: 1250-63. PMID 21861759 DOI: 10.1089/scd.2010.0578 |
0.92 |
|
| 2011 |
Tefferi A, Abdel-Wahab O, Cervantes F, Crispino JD, Finazzi G, Girodon F, Gisslinger H, Gotlib J, Kiladjian JJ, Levine RL, Licht JD, Mullally A, Odenike O, Pardanani A, Silver RT, et al. Mutations with epigenetic effects in myeloproliferative neoplasms and recent progress in treatment: Proceedings from the 5th International Post-ASH Symposium. Blood Cancer Journal. 1: e7. PMID 23471017 DOI: 10.1038/bcj.2011.4 |
0.92 |
|
| 2011 |
Rice KL, Lin X, Wolniak K, Ebert BL, Berkofsky-Fessler W, Buzzai M, Sun Y, Xi C, Elkin P, Levine R, Golub T, Gilliland DG, Crispino JD, Licht JD, Zhang W. Analysis of genomic aberrations and gene expression profiling identifies novel lesions and pathways in myeloproliferative neoplasms. Blood Cancer Journal. 1: e40. PMID 22829077 DOI: 10.1038/bcj.2011.39 |
0.92 |
|
| 2011 |
Khan I, Malinge S, Crispino JD. Myeloid leukemia in down syndrome Critical Reviews in Oncogenesis. 16: 25-36. PMID 22150305 |
0.92 |
|
| 2011 |
Wen Q, Goldenson B, Crispino JD. Normal and malignant megakaryopoiesis. Expert Reviews in Molecular Medicine. 13: e32. PMID 22018018 DOI: 10.1017/S1462399411002043 |
0.92 |
|
| 2011 |
Keerthivasan G, Wickrema A, Crispino JD. Erythroblast enucleation. Stem Cells International. 2011: 139851. PMID 22007239 DOI: 10.4061/2011/139851 |
0.92 |
|
| 2011 |
Stein BL, Crispino JD, Moliterno AR. Janus kinase inhibitors: an update on the progress and promise of targeted therapy in the myeloproliferative neoplasms. Current Opinion in Oncology. 23: 609-16. PMID 21993415 DOI: 10.1097/CCO.0b013e32834d1b22 |
0.92 |
|
| 2011 |
Mali RS, Ramdas B, Ma P, Shi J, Munugalavadla V, Sims E, Wei L, Vemula S, Nabinger SC, Goodwin CB, Chan RJ, Traina F, Visconte V, Tiu RV, Lewis TA, ... ... Crispino JD, et al. Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL. Cancer Cell. 20: 357-69. PMID 21907926 DOI: 10.1016/j.ccr.2011.07.016 |
0.92 |
|
| 2011 |
Park E, Gang EJ, Hsieh YT, Schaefer P, Chae S, Klemm L, Huantes S, Loh M, Conway EM, Kang ES, Hoe Koo H, Hofmann WK, Heisterkamp N, Pelus L, Keerthivasan G, ... Crispino J, et al. Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia. Blood. 118: 2191-9. PMID 21715311 DOI: 10.1182/blood-2011-04-351239 |
0.36 |
|
| 2011 |
Eliades A, Papadantonakis N, Bhupatiraju A, Burridge KA, Johnston-Cox HA, Migliaccio AR, Crispino JD, Lucero HA, Trackman PC, Ravid K. Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase. The Journal of Biological Chemistry. 286: 27630-8. PMID 21665949 DOI: 10.1074/jbc.M111.243113 |
0.92 |
|
| 2011 |
Doré LC, Crispino JD. Transcription factor networks in erythroid cell and megakaryocyte development. Blood. 118: 231-9. PMID 21622645 DOI: 10.1182/blood-2011-04-285981 |
0.92 |
|
| 2010 |
Small S, Keerthivasan G, Huang Z, Gurbuxani S, Crispino JD. Overexpression of survivin initiates hematologic malignancies in vivo Leukemia. 24: 1920-1926. PMID 20882051 DOI: 10.1038/leu.2010.198 |
0.92 |
|
| 2010 |
Huang QQ, Perlman H, Huang Z, Birkett R, Kan L, Agrawal H, Misharin A, Gurbuxani S, Crispino JD, Pope RM. FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasis. Blood. 116: 4968-77. PMID 20724542 DOI: 10.1182/blood-2009-11-252841 |
0.92 |
|
| 2010 |
Keerthivasan G, Small S, Liu H, Wickrema A, Crispino JD. Vesicle trafficking plays a novel role in erythroblast enucleation. Blood. 116: 3331-40. PMID 20644112 DOI: 10.1182/blood-2010-03-277426 |
0.92 |
|
| 2010 |
Gao Z, Huang Z, Olivey HE, Gurbuxani S, Crispino JD, Svensson EC. FOG-1-mediated recruitment of NuRD is required for cell lineage re-enforcement during haematopoiesis. The Embo Journal. 29: 457-68. PMID 20010697 DOI: 10.1038/emboj.2009.368 |
0.92 |
|
| 2009 |
Bhat R, Malinge S, Gamis AS, Sorrell AD, Hilden JM, Ketterling RP, Paietta E, Tallman MS, Crispino JD. Mutational analysis of candidate tumor-associated genes in acute megakaryoblastic leukemia Leukemia. 23: 2159-2160. PMID 19657363 DOI: 10.1038/leu.2009.159 |
0.92 |
|
| 2009 |
Huang Z, Dore LC, Li Z, Orkin SH, Feng G, Lin S, Crispino JD. GATA-2 reinforces megakaryocyte development in the absence of GATA-1. Molecular and Cellular Biology. 29: 5168-80. PMID 19620289 DOI: 10.1128/MCB.00482-09 |
0.92 |
|
| 2009 |
Chou ST, Khandros E, Bailey LC, Nichols KE, Vakoc CR, Yao Y, Huang Z, Crispino JD, Hardison RC, Blobel GA, Weiss MJ. Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate. Blood. 114: 983-94. PMID 19491391 DOI: 10.1182/blood-2009-03-207944 |
0.92 |
|
| 2009 |
Abdel-Wahab O, Mullally A, Hedvat C, Garcia-Manero G, Patel J, Wadleigh M, Malinge S, Yao J, Kilpivaara O, Bhat R, Huberman K, Thomas S, Dolgalev I, Heguy A, Paietta E, ... ... Crispino JD, et al. Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood. 114: 144-7. PMID 19420352 DOI: 10.1182/blood-2009-03-210039 |
0.92 |
|
| 2009 |
Wen Q, Leung C, Huang Z, Small S, Reddi AL, Licht JD, Crispino JD. Survivin is not required for the endomitotic cell cycle of megakaryocytes. Blood. 114: 153-6. PMID 19339696 DOI: 10.1182/blood-2008-11-190801 |
0.92 |
|
| 2009 |
Stankiewicz MJ, Crispino JD. ETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cells. Blood. 113: 3337-47. PMID 19168790 DOI: 10.1182/blood-2008-08-174813 |
0.92 |
|
| 2009 |
Malinge S, Izraeli S, Crispino JD. Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome. Blood. 113: 2619-28. PMID 19139078 DOI: 10.1182/blood-2008-11-163501 |
0.92 |
|
| 2008 |
McCrann DJ, Yezefski T, Nguyen HG, Papadantonakis N, Liu H, Wen Q, Crispino JD, Ravid K. Survivin overexpression alone does not alter megakaryocyte ploidy nor interfere with erythroid/megakaryocytic lineage development in transgenic mice. Blood. 111: 4092-5. PMID 18245663 DOI: 10.1182/blood-2007-11-122150 |
0.92 |
|
| 2008 |
Kang JA, Zhou Y, Weis TL, Liu H, Ulaszek J, Satgurunathan N, Zhou L, van Besien K, Crispino J, Verma A, Low PS, Wickrema A. Osteopontin regulates actin cytoskeleton and contributes to cell proliferation in primary erythroblasts. The Journal of Biological Chemistry. 283: 6997-7006. PMID 18174176 DOI: 10.1074/jbc.M706712200 |
0.92 |
|
| 2008 |
Kirsammer G, Jilani S, Liu H, Davis E, Gurbuxani S, Le Beau MM, Crispino JD. Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome. Blood. 111: 767-75. PMID 17901249 DOI: 10.1182/blood-2007-04-085670 |
0.92 |
|
| 2007 |
Huang Z, Richmond TD, Muntean AG, Barber DL, Weiss MJ, Crispino JD. STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice. The Journal of Clinical Investigation. 117: 3890-9. PMID 18060035 DOI: 10.1172/JCI33010 |
0.92 |
|
| 2007 |
Wickrema A, Crispino JD. Erythroid and megakaryocytic transformation Oncogene. 26: 6803-6815. PMID 17934487 DOI: 10.1038/sj.onc.1210763 |
0.92 |
|
| 2007 |
Norton A, Fisher C, Liu H, Wen Q, Mundschau G, Fuster JL, Hasle H, Zeller B, Webb DK, O'Marcaigh A, Sorrell A, Hilden J, Gamis A, Crispino JD, Vyas P. Analysis of JAK3, JAK2, and C-MPL mutations in transient myeloproliferative disorder and myeloid leukemia of Down syndrome blasts in children with Down syndrome. Blood. 110: 1077-9. PMID 17644747 DOI: 10.1182/blood-2007-03-080374 |
0.92 |
|
| 2007 |
Leung CG, Xu Y, Mularski B, Liu H, Gurbuxani S, Crispino JD. Requirements for survivin in terminal differentiation of erythroid cells and maintenance of hematopoietic stem and progenitor cells. The Journal of Experimental Medicine. 204: 1603-11. PMID 17576776 DOI: 10.1084/jem.20062395 |
0.92 |
|
| 2007 |
Joslin JM, Fernald AA, Tennant TR, Davis EM, Kogan SC, Anastasi J, Crispino JD, Le Beau MM. Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Blood. 110: 719-26. PMID 17420284 DOI: 10.1182/blood-2007-01-068809 |
0.92 |
|
| 2007 |
Muntean AG, Pang L, Poncz M, Dowdy SF, Blobel GA, Crispino JD. Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization. Blood. 109: 5199-207. PMID 17317855 DOI: 10.1182/blood-2006-11-059378 |
0.92 |
|
| 2007 |
Vyas P, Crispino JD. Molecular insights into Down syndrome-associated leukemia. Current Opinion in Pediatrics. 19: 9-14. PMID 17224656 DOI: 10.1097/MOP.0b013e328013e7b2 |
0.92 |
|
| 2007 |
Crispino JD. On the origins of megakaryocytes Blood. 109: 1340-1341. DOI: 10.1182/blood-2006-12-060269 |
0.92 |
|
| 2006 |
Walters DK, Mercher T, Gu TL, O'Hare T, Tyner JW, Loriaux M, Goss VL, Lee KA, Eide CA, Wong MJ, Stoffregen EP, McGreevey L, Nardone J, Moore SA, Crispino J, et al. Activating alleles of JAK3 in acute megakaryoblastic leukemia. Cancer Cell. 10: 65-75. PMID 16843266 DOI: 10.1016/j.ccr.2006.06.002 |
0.92 |
|
| 2006 |
Muntean AG, Ge Y, Taub JW, Crispino JD. Transcription factor GATA-1 and Down syndrome leukemogenesis. Leukemia & Lymphoma. 47: 986-97. PMID 16840187 DOI: 10.1080/10428190500485810 |
0.92 |
|
| 2006 |
Xu Y, Leung CG, Lee DC, Kennedy BK, Crispino JD. MTB, the murine homolog of condensin II subunit CAP-G2, represses transcription and promotes erythroid cell differentiation. Leukemia. 20: 1261-9. PMID 16673016 DOI: 10.1038/sj.leu.2404252 |
0.92 |
|
| 2006 |
Crispino JD. Up and down in Down syndrome: AMKL Blood. 107: 1251-1252. DOI: 10.1182/blood-2005-11-4672 |
0.92 |
|
| 2005 |
Gurbuxani S, Xu Y, Keerthivasan G, Wickrema A, Crispino JD. Differential requirements for survivin in hematopoietic cell development. Proceedings of the National Academy of Sciences of the United States of America. 102: 11480-5. PMID 16055565 DOI: 10.1073/pnas.0500303102 |
0.92 |
|
| 2005 |
Muntean AG, Crispino JD. Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development. Blood. 106: 1223-31. PMID 15860665 DOI: 10.1182/blood-2005-02-0551 |
0.92 |
|
| 2005 |
Crispino JD. GATA1 in normal and malignant hematopoiesis. Seminars in Cell & Developmental Biology. 16: 137-47. PMID 15659348 DOI: 10.1016/j.semcdb.2004.11.002 |
0.92 |
|
| 2005 |
Crispino JD. GATA1 mutations in Down syndrome: implications for biology and diagnosis of children with transient myeloproliferative disorder and acute megakaryoblastic leukemia. Pediatric Blood & Cancer. 44: 40-4. PMID 15390312 DOI: 10.1002/pbc.20066 |
0.92 |
|
| 2004 |
Taub JW, Mundschau G, Ge Y, Poulik JM, Qureshi F, Jensen T, James SJ, Matherly LH, Wechsler J, Crispino JD. Prenatal origin of GATA1 mutations may be an initiating step in the development of megakaryocytic leukemia in Down syndrome. Blood. 104: 1588-9. PMID 15317736 DOI: 10.1182/blood-2004-04-1563 |
0.92 |
|
| 2004 |
Smith ED, Xu Y, Tomson BN, Leung CG, Fujiwara Y, Orkin SH, Crispino JD. More than blood, a novel gene required for mammalian postimplantation development. Molecular and Cellular Biology. 24: 1168-73. PMID 14729962 DOI: 10.1128/MCB.24.3.1168-1173.2004 |
0.92 |
|
| 2004 |
Gurbuxani S, Vyas P, Crispino JD. Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome. Blood. 103: 399-406. PMID 14512321 DOI: 10.1182/blood-2003-05-1556 |
0.92 |
|
| 2003 |
Greene ME, Mundschau G, Wechsler J, McDevitt M, Gamis A, Karp J, Gurbuxani S, Arceci R, Crispino JD. Mutations in GATA1 in both transient myeloproliferative disorder and acute megakaryoblastic leukemia of Down syndrome. Blood Cells, Molecules & Diseases. 31: 351-6. PMID 14636651 DOI: 10.1016/j.bcmd.2003.08.001 |
0.92 |
|
| 2003 |
Karnauskas R, Niu Q, Talapatra S, Plas DR, Greene ME, Crispino JD, Rudin CM. Bcl-x(L) and Akt cooperate to promote leukemogenesis in vivo. Oncogene. 22: 688-98. PMID 12569361 DOI: 10.1038/sj.onc.1206159 |
0.92 |
|
| 2003 |
Mundschau G, Gurbuxani S, Gamis AS, Greene ME, Arceci RJ, Crispino JD. Mutagenesis of GATA1 is an initiating event in Down syndrome leukemogenesis. Blood. 101: 4298-300. PMID 12560215 DOI: 10.1182/blood-2002-12-3904 |
0.92 |
|
| 2002 |
Wang X, Crispino JD, Letting DL, Nakazawa M, Poncz M, Blobel GA. Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: role of Ets transcription factors. The Embo Journal. 21: 5225-34. PMID 12356738 DOI: 10.1093/emboj/cdf527 |
0.92 |
|
| 2002 |
Tevosian SG, Albrecht KH, Crispino JD, Fujiwara Y, Eicher EM, Orkin SH. Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2. Development (Cambridge, England). 129: 4627-34. PMID 12223418 |
0.92 |
|
| 2002 |
Wechsler J, Greene M, McDevitt MA, Anastasi J, Karp JE, Le Beau MM, Crispino JD. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nature Genetics. 32: 148-52. PMID 12172547 DOI: 10.1038/ng955 |
0.92 |
|
| 2002 |
Chang AN, Cantor AB, Fujiwara Y, Lodish MB, Droho S, Crispino JD, Orkin SH. GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 9237-42. PMID 12077323 DOI: 10.1073/pnas.142302099 |
0.92 |
|
| 2002 |
Crispino JD, Orkin SH. The use of altered specificity mutants to probe specific protein-protein interactions involved in the activation of GATA-1 target genes. Methods (San Diego, Calif.). 26: 84-92. PMID 12054907 DOI: 10.1016/S1046-2023(02)00010-5 |
0.92 |
|
| 2001 |
Crispino JD, Lodish MB, Thurberg BL, Litovsky SH, Collins T, Molkentin JD, Orkin SH. Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors Genes and Development. 15: 839-844. PMID 11297508 DOI: 10.1101/gad.875201 |
0.92 |
|
| 2000 |
Querfurth E, Schuster M, Kulessa H, Crispino JD, Döderlein G, Orkin SH, Graf T, Nerlov C. Antagonism between C/EBPβ and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors Genes and Development. 14: 2515-2525. PMID 11018018 DOI: 10.1101/gad.177200 |
0.92 |
|
| 2000 |
Deconinck AE, Mead PE, Tevosian SG, Crispino JD, Katz SG, Zon LI, Orkin SH. FOG acts as a repressor of red blood cell development in Xenopus Development. 127: 2031-2040. PMID 10769228 |
0.92 |
|
| 2000 |
Nichols KE, Crispino JD, Poncz M, White JG, Orkin SH, Maris JM, Weiss MJ. Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA 1 Nature Genetics. 24: 266-270. PMID 10700180 DOI: 10.1038/73480 |
0.92 |
|
| 1999 |
Crispino JD, Lodish MB, MacKay JP, Orkin SH. Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: The GATA-1:FOG complex Molecular Cell. 3: 219-228. PMID 10078204 DOI: 10.1016/S1097-2765(00)80312-3 |
0.92 |
|
| 1997 |
Macmillan AM, Mccaw PS, Crispino JD, Sharp PA. SC35-mediated reconstitution of splicing in U2AF-depleted nuclear extract Proceedings of the National Academy of Sciences of the United States of America. 94: 133-136. PMID 8990173 DOI: 10.1073/pnas.94.1.133 |
0.92 |
|
| 1996 |
Crispino JD, Mermoud JE, Lamond AI, Sharp PA. Cis-acting elements distinct from the 5' splice site promote U1-independent pre-mRNA splicing. Rna (New York, N.Y.). 2: 664-73. PMID 8756409 |
0.92 |
|
| 1995 |
Crispino JD, Sharp PA. A U6 snRNA:pre-mRNA interaction can be rate-limiting for U1-independent splicing Genes and Development. 9: 2314-2323. PMID 7557384 |
0.92 |
|
| 1994 |
Crispino JD, Blencowe BJ, Sharp PA. Complementation by SR proteins of pre-mRNA splicing reactions depleted of U1 snRNP. Science (New York, N.Y.). 265: 1866-9. PMID 8091213 |
0.92 |
|
| 1991 |
Lessard PA, Allen RD, Bernier F, Crispino JD, Fujiwara T, Beachy RN. Multiple nuclear factors interact with upstream sequences of differentially regulated β-conglycinin genes Plant Molecular Biology. 16: 397-413. PMID 1893110 DOI: 10.1007/BF00023991 |
0.92 |
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