Umesh R. Desai - Publications

1998- Virginia Commonwealth University, Richmond, VA, United States 
Pharmaceutical Chemistry, Biochemistry

223 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Pingali P, Wu YJ, Boothello R, Sharon C, Li H, Sistla S, Sankaranarayanan NV, Desai UR, Le AT, Doebele RC, Muldoon LL, Patel BB, Neuwelt A. High dose acetaminophen inhibits STAT3 and has free radical independent anti-cancer stem cell activity. Neoplasia (New York, N.Y.). 23: 348-359. PMID 33640759 DOI: 10.1016/j.neo.2021.02.001  1
2020 Kalita M, Chua JS, Boothello RS, Joice A, Antelope O, Roy A, Anandh Babu PV, Saijoh Y, Desai UR, Kuberan B. Visualizing antithrombin-binding 3--sulfated heparan sulfate motifs on cell surfaces. Chemical Communications (Cambridge, England). PMID 33146178 DOI: 10.1039/d0cc05893a  1
2020 Roy A, Miyai Y, Rossi A, Paraswar K, Desai U, Saijoh Y, Kuberan B. Metabolic engineering of non-pathogenic Escherichia coli strains for the controlled production of low molecular weight heparosan and size-specific heparosan oligosaccharides. Biochimica Et Biophysica Acta. General Subjects. 129765. PMID 33069832 DOI: 10.1016/j.bbagen.2020.129765  1
2020 Tiwari V, Tandon R, Sankaranarayanan NV, Beer JC, Kohlmeir EK, Swanson-Mungerson M, Desai UR. Preferential recognition and antagonism of SARS-CoV-2 spike glycoprotein binding to 3- -sulfated heparan sulfate. Biorxiv : the Preprint Server For Biology. PMID 33052337 DOI: 10.1101/2020.10.08.331751  1
2020 Boothello RS, Sankaranarayanan NV, Afosah DK, Karuturi R, Al-Horani RA, Desai UR. Studies on fragment-based design of allosteric inhibitors of human factor XIa. Bioorganic & Medicinal Chemistry. 28: 115762. PMID 32992249 DOI: 10.1016/J.Bmc.2020.115762  1
2020 Morla S, Desai UR. Discovery of Sulfated Small Molecule Inhibitors of Matrix Metalloproteinase-8. Biomolecules. 10. PMID 32784891 DOI: 10.3390/biom10081166  1
2020 Tiwari V, Beer JC, Sankaranarayanan NV, Swanson-Mungerson M, Desai UR. Discovering small-molecule therapeutics against SARS-CoV-2. Drug Discovery Today. PMID 32574699 DOI: 10.1016/j.drudis.2020.06.017  1
2020 Rajarathnam K, Desai UR. Structural Insights Into How Proteoglycans Determine Chemokine-CXCR1/CXCR2 Interactions: Progress and Challenges. Frontiers in Immunology. 11: 660. PMID 32391006 DOI: 10.3389/Fimmu.2020.00660  1
2020 Sankaranarayanan NV, Bi Y, Kuberan B, Desai UR. Combinatorial virtual library screening analysis of antithrombin binding oligosaccharide motif generation by heparan sulfate 3--Sulfotransferase 1. Computational and Structural Biotechnology Journal. 18: 933-941. PMID 32346466 DOI: 10.1016/J.Csbj.2020.03.008  1
2020 Alabbas A, Desai UR. Enzyme immobilization offers a robust tool to scale up the production of longer, diverse, natural glycosaminoglycan oligosaccharides. Glycobiology. PMID 32193533 DOI: 10.1093/Glycob/Cwaa027  1
2020 Elste J, Kaltenbach D, Patel VR, Nguyen MT, Sharthiya H, Tandon R, Mehta SK, Volin MV, Fornaro M, Tiwari V, Desai UR. Inhibition of Human Cytomegalovirus Entry into Host Cells Through a Pleiotropic Small Molecule. International Journal of Molecular Sciences. 21. PMID 32121406 DOI: 10.3390/Ijms21051676  1
2020 Nagarajan B, Sankaranarayanan NV, Desai UR. Rigorous Analysis of Free Solution Glycosaminoglycan Dynamics Using Simple, New Tools. Glycobiology. PMID 32080710 DOI: 10.1093/Glycob/Cwaa015  1
2020 O'Hara CP, Boothello RS, Morla S, Vera A, Afosah DK, Sankaranarayanan NV, Nagarajan B, Sharon C, Patel BB, Desai UR. Abstract 6353: Cholesterol modification enhances potency and pharmacokinetic properties of a selective cancer stem cell targeting agent Cancer Research. 80: 6353-6353. DOI: 10.1158/1538-7445.Am2020-6353  1
2019 Sistla JC, Desai UR. A Robust, One-step FRET Assay for Human Heparanase. Bio-Protocol. 9: e3356. PMID 33654855 DOI: 10.21769/BioProtoc.3356  1
2019 Al-Horani RA, Abdelfadiel EI, Afosah DK, Morla S, Sistla JC, Mohammed B, Martin EJ, Sakagami M, Brophy DF, Desai UR. A Synthetic Heparin Mimetic That Allosterically Inhibits Factor XIa and Reduces Thrombosis In Vivo Without Enhanced Risk of Bleeding. Journal of Thrombosis and Haemostasis : Jth. PMID 31397071 DOI: 10.1111/Jth.14606  1
2019 Nagarajan B, Sankaranarayanan NV, Desai UR. Perspective on computational simulations of glycosaminoglycans. Wiley Interdisciplinary Reviews. Computational Molecular Science. 9. PMID 31080520 DOI: 10.1002/Wcms.1388  0.01
2019 Morla S, Sankaranarayanan NV, Afosah DK, Kumar M, Kummarapurugu AB, Voynow J, Desai UR. On the Process of Discovering Leads that Target the Heparin-Binding Site of Neutrophil Elastase in the Sputum of Cystic Fibrosis Patients. Journal of Medicinal Chemistry. PMID 31074986 DOI: 10.1021/Acs.Jmedchem.9B00379  1
2019 Sistla JC, Morla S, Alabbas AB, Kalathur RC, Sharon C, Patel BB, Desai UR. Polymeric fluorescent heparin as one-step FRET substrate of human heparanase. Carbohydrate Polymers. 205: 385-391. PMID 30446119 DOI: 10.1016/J.Carbpol.2018.10.071  1
2019 Sistla J, Desai U. A Robust, One-step FRET Assay for Human Heparanase Bio-Protocol. 9. DOI: 10.21769/bioprotoc.3356  0.01
2018 Gallegos KM, Taylor CR, Rabulinski DJ, Del Toro R, Girgis DE, Jourha D, Tiwari V, Desai UR, Ramsey KH. A Synthetic, Small, Sulfated Agent Is a Promising Inhibitor of . Infection . Frontiers in Microbiology. 9: 3269. PMID 30700982 DOI: 10.3389/Fmicb.2018.03269  1
2018 Periasamy S, Lin CH, Nagarajan B, Sankaranarayanan NV, Desai UR, Liu MY. Mucoadhesive role of tamarind xyloglucan on inflammation attenuates ulcerative colitis. Journal of Functional Foods. 47: 1-10. PMID 30555535 DOI: 10.1016/J.Jff.2018.05.035  1
2018 Kaltenbach DD, Jaishankar D, Hao M, Beer JC, Volin MV, Desai UR, Tiwari V. Sulfotransferase and Heparanase: Remodeling Engines in Promoting Virus Infection and Disease Development. Frontiers in Pharmacology. 9: 1315. PMID 30555321 DOI: 10.3389/fphar.2018.01315  1
2018 Majmudar H, Hao M, Sankaranarayanan NV, Zanotti B, Volin MV, Desai UR, Tiwari V. A synthetic glycosaminoglycan mimetic blocks HSV-1 infection in human iris stromal cells. Antiviral Research. PMID 30481525 DOI: 10.1016/j.antiviral.2018.11.007  1
2018 Boothello RS, Patel NJ, Sharon C, Abdelfadiel EI, Morla S, Brophy DF, Lippman HR, Desai UR, Patel BB. A Unique Non-Saccharide Mimetic of Heparin Hexasaccharide Inhibits Colon Cancer Stem Cells via p38 MAP Kinase Activation. Molecular Cancer Therapeutics. PMID 30337351 DOI: 10.1158/1535-7163.Mct-18-0104  1
2018 Sepuru KM, Nagarajan B, Desai UR, Rajarathnam K. Structural basis, stoichiometry, and thermodynamics of binding of the chemokines KC and MIP2 to the glycosaminoglycan heparin. The Journal of Biological Chemistry. PMID 30257866 DOI: 10.1074/Jbc.Ra118.004866  1
2018 Gangji RN, Sankaranarayanan NV, Elste J, Al-Horani RA, Afosah DK, Joshi R, Tiwari V, Desai UR. Inhibition of Herpes Simplex Virus-1 Entry into Human Cells by Nonsaccharide Glycosaminoglycan Mimetics. Acs Medicinal Chemistry Letters. 9: 797-802. PMID 30128070 DOI: 10.1021/Acsmedchemlett.7B00364  1
2018 Joseph PRB, Sawant KV, Iwahara J, Garofalo RP, Desai UR, Rajarathnam K. Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions. Scientific Reports. 8: 12289. PMID 30115951 DOI: 10.1038/S41598-018-30697-Y  1
2018 Kummarapurugu AB, Afosah DK, Sankaranarayanan NV, Gangji RN, Zheng S, Kennedy TP, Rubin BK, Voynow JA, Desai UR. Molecular principles for heparin oligosaccharide-based inhibition of neutrophil elastase in cystic fibrosis. The Journal of Biological Chemistry. PMID 29903912 DOI: 10.1074/Jbc.Ra118.002644  1
2018 Abdel Aziz MH, Desai UR. Novel heparin mimetics reveal cooperativity between exosite 2 and sodium-binding site of thrombin. Thrombosis Research. 165: 61-67. PMID 29573721 DOI: 10.1016/j.thromres.2018.03.013  1
2018 Tran DT, Zhang T, Stutsman R, Might M, Desai UR, Kuberan B. anexVis: Visual analytics framework for analysis of RNA expression. Bioinformatics (Oxford, England). PMID 29506198 DOI: 10.1093/Bioinformatics/Bty122  1
2018 Afosah DK, Verespy S, Al-Horani RA, Boothello RS, Karuturi R, Desai UR. A small group of sulfated benzofurans induces steady-state submaximal inhibition of thrombin. Bioorganic & Medicinal Chemistry Letters. PMID 29459207 DOI: 10.1016/J.Bmcl.2018.01.069  1
2018 Sankaranarayanan NV, Nagarajan B, Desai UR. So you think computational approaches to understanding glycosaminoglycan-protein interactions are too dry and too rigid? Think again! Current Opinion in Structural Biology. 50: 91-100. PMID 29328962 DOI: 10.1016/J.Sbi.2017.12.004  1
2018 Boothello RS, Patel NJ, Damle PK, Sharon C, Chougoni KK, Desai UR, Grossman SR, Patel BB. Abstract 3460: p38-p14ARF-CtBP2 axis as a novel regulator of CSC phenotype and tumor cell dormancy Cancer Research. 78: 3460-3460. DOI: 10.1158/1538-7445.Am2018-3460  1
2018 Boothello RS, Patel N, Sharon C, Karuturi R, Abdelfadiel EI, Morla S, Brophy DF, Lippman R, Desai UR, Patel BB. 518 - G2.2, a Unique Non-Sachharide Mimetic of Heparin Hexasaccharide Selectively Inhibits Cancerous but Protects Adult Colonic Stem/Progenitor Cells via a Common Mechanism of Induction of P38 Mitogen-Activated Protein Kinase Gastroenterology. 154: S-114-S-115. DOI: 10.1016/S0016-5085(18)30817-5  0.01
2018 Periasamy S, Lin C, Nagarajan B, Sankaranarayanan NV, Desai UR, Liu M. Tamarind xyloglucan attenuates dextran sodium sulfate induced ulcerative colitis: Role of antioxidation Journal of Functional Foods. 42: 327-338. DOI: 10.1016/J.Jff.2018.01.014  0.01
2017 Chiang MJ, Musayev FN, Kosikova M, Lin Z, Gao Y, Mosier PD, Althufairi B, Ye Z, Zhou Q, Desai UR, Xie H, Safo MK. Maintaining pH-dependent conformational flexibility of M1 is critical for efficient influenza A virus replication. Emerging Microbes & Infections. 6: e108. PMID 29209052 DOI: 10.1038/Emi.2017.96  1
2017 Monneau YR, Luo L, Sankaranarayanan NV, Nagarajan B, Vivès RR, Baleux F, Desai UR, Arenzana-Seidedos F, Lortat-Jacob H. Solution structure of CXCL13 and heparan sulfate binding show that GAG binding site and cellular signalling rely on distinct domains. Open Biology. 7. PMID 29070611 DOI: 10.1098/Rsob.170133  1
2017 Bhushan I, Alabbas A, Kuberan B, Gupta RB, Desai UR. IMMOBILIZATION ALTERS HEPARIN CLEAVING PROPERTIES OF HEPARINASE I. Glycobiology. PMID 28973365 DOI: 10.1093/Glycob/Cwx074  1
2017 Truong TM, Li H, Dhapare S, Desai UR, Voelkel NF, Sakagami M. Sulfated dehydropolymer of caffeic acid: In vitro anti-lung cell death activity and in vivo intervention in emphysema induced by VEGF receptor blockade. Pulmonary Pharmacology & Therapeutics. PMID 28648907 DOI: 10.1016/J.Pupt.2017.06.007  1
2017 Bhushan I, Alabbas A, Sistla JC, Saraswat R, Desai UR, Gupta RB. Heparin Depolymerization by Immobilized Heparinase. International Journal of Biological Macromolecules. PMID 28300590 DOI: 10.1016/J.Ijbiomac.2017.03.036  1
2017 Nagarajan B, Sankaranarayanan NV, Patel BB, Desai UR. A molecular dynamics-based algorithm for evaluating the glycosaminoglycan mimicking potential of synthetic, homogenous, sulfated small molecules. Plos One. 12: e0171619. PMID 28182755 DOI: 10.1371/Journal.Pone.0171619  1
2017 Sankarayanarayanan NV, Strebel TR, Boothello RS, Sheerin K, Raghuraman A, Sallas F, Mosier PD, Watermeyer ND, Oscarson S, Desai UR. A Hexasaccharide Containing Rare 2-O-Sulfate-Glucuronic Acid Residues Selectively Activates Heparin Cofactor II. Angewandte Chemie (International Ed. in English). PMID 28124818 DOI: 10.1002/Anie.201609541  1
2016 Afosah DK, Al-Horani RA, Sankaranarayanan NV, Desai UR. Potent, Selective, Allosteric Inhibition of Human Plasmin by Sulfated Non-Saccharide Glycosaminoglycan Mimetics. Journal of Medicinal Chemistry. PMID 27976897 DOI: 10.1021/acs.jmedchem.6b01474  1
2016 Mangrum JB, Mehta AY, Alabbas AB, Desai UR, Hawkridge AM. Comparative analysis of INLIGHT™-labeled enzymatically depolymerized heparin by reverse-phase chromatography and high-performance mass spectrometry. Analytical and Bioanalytical Chemistry. PMID 27888308 DOI: 10.1007/s00216-016-0055-2  1
2016 Patel NJ, Sharon C, Baranwal S, Boothello RS, Desai UR, Patel BB. Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase. Oncotarget. PMID 27705927 DOI: 10.18632/Oncotarget.12358  1
2016 Zheng S, Kummarapurugu AB, Afosah DK, Sankaranarayanan NV, Boothello RS, Desai UR, Kennedy T, Voynow JA. 2-O, 3-O Desulfated Heparin Blocks HMGB1 Release by Inhibition of p300 Acetyltransferase Activity. American Journal of Respiratory Cell and Molecular Biology. PMID 27585400 DOI: 10.1165/rcmb.2016-0069OC  1
2016 Mosier PD, Chiang MJ, Lin Z, Gao Y, Althufairi B, Zhou Q, Musayev F, Safo MK, Xie H, Desai UR. Broad Spectrum Anti-Influenza Agents by Inhibiting Self-Association of Matrix Protein 1. Scientific Reports. 6: 32340. PMID 27573445 DOI: 10.1038/Srep32340  1
2016 Sarkar A, Yu W, Desai UR, MacKerell AD, Mosier PD. Estimating glycosaminoglycan-protein interaction affinity: Water dominates the specific antithrombin-heparin interaction. Glycobiology. PMID 27496757 DOI: 10.1093/Glycob/Cww073  1
2016 Sepuru KM, Nagarajan B, Desai UR, Rajarathnam K. Molecular basis of chemokine CXCL5-glycosaminoglycan interactions. The Journal of Biological Chemistry. PMID 27471273 DOI: 10.1074/Jbc.M116.745265  1
2016 Al-Horani RA, Karuturi R, Lee M, Afosah DK, Desai UR. Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile. Plos One. 11: e0160189. PMID 27467511 DOI: 10.1371/journal.pone.0160189  1
2016 Wood JP, Baumann Kreuziger LM, Desai UR, Mast AE. Blocking inhibition of prothrombinase by tissue factor pathway inhibitor alpha: a procoagulant property of heparins. British Journal of Haematology. PMID 27301751 DOI: 10.1111/Bjh.14182  1
2016 Verespy Iii S, Mehta AY, Afosah D, Al-Horani RA, Desai UR. Allosteric Partial Inhibition of Monomeric Proteases. Sulfated Coumarins Induce Regulation, not just Inhibition, of Thrombin. Scientific Reports. 6: 24043. PMID 27053426 DOI: 10.1038/Srep24043  1
2016 Al-Horani RA, Desai UR. Factor XIa inhibitors: A review of the patent literature. Expert Opinion On Therapeutic Patents. PMID 26881476 DOI: 10.1517/13543776.2016.1154045  1
2016 Agre P, Bertozzi C, Bissell M, Campbell KP, Cummings RD, Desai UR, Estes M, Flotte T, Fogleman G, Gage F, Ginsburg D, Gordon JI, Hart G, Hascall V, Kiessling L, et al. Training the next generation of biomedical investigators in glycosciences. The Journal of Clinical Investigation. 126: 405-408. PMID 26829621 DOI: 10.1172/Jci85905  1
2016 Mehta AY, Mohammed BM, Martin EJ, Brophy DF, Gailani D, Desai UR. Allosterism-based Simultaneous, Dual Anticoagulant and Antiplatelet Action Allosteric Inhibitor Targeting the Glycoprotein Ibα and Heparin-Binding Site of Thrombin. Journal of Thrombosis and Haemostasis : Jth. PMID 26748875 DOI: 10.1111/Jth.13254  1
2016 Peracha ZH, Ahmed SB, Desai A, Peracha-Riyaz M, Kumar N, Desai UR. Saturday Night Retinopathy: Characterization of a Rare Ophthalmic Condition. Ophthalmic Surgery, Lasers & Imaging Retina. 47: 85-9. PMID 26731217 DOI: 10.3928/23258160-20151214-15  1
2015 Sarkar A, Desai UR. A Simple Method for Discovering Druggable, Specific Glycosaminoglycan-Protein Systems. Elucidation of Key Principles from Heparin/Heparan Sulfate-Binding Proteins. Plos One. 10: e0141127. PMID 26488293 DOI: 10.1371/journal.pone.0141127  1
2015 Joseph PR, Mosier PD, Desai UR, Rajarathnam K. Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions. The Biochemical Journal. 472: 121-33. PMID 26371375 DOI: 10.1042/Bj20150059  1
2015 Namachivayam K, Coffing HP, Sankaranarayanan NV, Jin Y, MohanKumar K, Frost BL, Blanco CL, Patel AL, Meier PP, Garzon SA, Desai UR, Maheshwari A. Transforming Growth Factor-β2 is sequestered in Preterm Human Milk by Chondroitin Sulfate Proteoglycans. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00126.2015. PMID 26045614 DOI: 10.1152/ajpgi.00126.2015  1
2015 Al-Horani RA, Gailani D, Desai UR. Allosteric inhibition of factor XIa. Sulfated non-saccharide glycosaminoglycan mimetics as promising anticoagulants. Thrombosis Research. 136: 379-87. PMID 25935648 DOI: 10.1016/J.Thromres.2015.04.017  1
2015 Wang A, Sankaranarayanan NV, Yanagishita M, Templeton DM, Desai UR, Sugahara K, Wang CP, Hascall VC. Heparin interaction with a receptor on hyperglycemic dividing cells prevents intracellular hyaluronan synthesis and autophagy responses in models of type 1 diabetes. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 25892563 DOI: 10.1016/j.matbio.2015.04.003  1
2015 Wang X, Wang Z, Sidhu PS, Desai UR, Zhou Q. 6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells. Plos One. 10: e0116409. PMID 25790236 DOI: 10.1371/Journal.Pone.0116409  1
2015 Boothello RS, Sarkar A, Tran VM, Nguyen TK, Sankaranarayanan NV, Mehta AY, Alabbas A, Brown S, Rossi A, Joice AC, Mencio CP, Quintero MV, Kuberan B, Desai UR. Chemoenzymatically Prepared Heparan Sulfate Containing Rare 2-O-Sulfonated Glucuronic Acid Residues. Acs Chemical Biology. 10: 1485-94. PMID 25742429 DOI: 10.1021/Acschembio.5B00071  1
2015 Wang C, Jin Y, Desai UR, Yadavalli VK. Investigation of the heparin-thrombin interaction by dynamic force spectroscopy. Biochimica Et Biophysica Acta. 1850: 1099-106. PMID 25647100 DOI: 10.1016/J.Bbagen.2015.01.016  1
2015 Al-Horani RA, Karuturi R, White DT, Desai UR. Plasmin regulation through allosteric, sulfated, small molecules. Molecules (Basel, Switzerland). 20: 608-24. PMID 25569517 DOI: 10.3390/molecules20010608  1
2015 Balagurunathan K, Nakato H, Desai UR. Preface. Glycosaminoglycans. Methods in Molecular Biology (Clifton, N.J.). 1229: v. PMID 25489643  1
2015 Liang A, Desai UR. Studying glycosaminoglycan-protein interactions using capillary electrophoresis. Methods in Molecular Biology (Clifton, N.J.). 1229: 355-75. PMID 25325965 DOI: 10.1007/978-1-4939-1714-3_28  1
2015 Boothello RS, Al-Horani RA, Desai UR. Glycosaminoglycan-protein interaction studies using fluorescence spectroscopy. Methods in Molecular Biology (Clifton, N.J.). 1229: 335-53. PMID 25325964 DOI: 10.1007/978-1-4939-1714-3_27  1
2015 Sankaranarayanan NV, Sarkar A, Desai UR, Mosier PD. Designing "high-affinity, high-specificity" glycosaminoglycan sequences through computerized modeling. Methods in Molecular Biology (Clifton, N.J.). 1229: 289-314. PMID 25325961 DOI: 10.1007/978-1-4939-1714-3_24  1
2015 Al-Horani RA, Karuturi R, Verespy S, Desai UR. Synthesis of glycosaminoglycan mimetics through sulfation of polyphenols. Methods in Molecular Biology (Clifton, N.J.). 1229: 49-67. PMID 25325944 DOI: 10.1007/978-1-4939-1714-3_7  1
2015 Patel BB, Patel NJ, Sankaranarayanan NV, Nagarajan B, Desai UR. 160 Unique Non-Saccharide Glycosaminoglycan Mimetics Selectively Target Cancer Stem Cells Through Specific Alteration of Growth Factor Receptor Activation via Mimicry of Heparin Hexasaccharide Gastroenterology. 148: S-43. DOI: 10.1016/S0016-5085(15)30149-9  0.01
2015 Boothello RS, Al-Horani RA, Desai UR. Glycosaminoglycan–protein Interaction Studies Using Fluorescence Spectroscopy Methods in Molecular Biology. 1229: 335-353. DOI: 10.1007/978-1-4939-1714-3_27,  1
2014 Sidhu PS, Zhou Q, Desai UR. A simple, general approach of allosteric coagulation enzyme inhibition through monosulfated hydrophobic scaffolds. Bioorganic & Medicinal Chemistry Letters. 24: 5716-20. PMID 25453807 DOI: 10.1016/J.Bmcl.2014.10.059  1
2014 Safo MK, Musayev FN, Mosier PD, Zhou Q, Xie H, Desai UR. Crystal structures of influenza A virus matrix protein M1: variations on a theme. Plos One. 9: e109510. PMID 25295515 DOI: 10.1371/Journal.Pone.0109510  1
2014 Henry BL, Desai UR. Sulfated low molecular weight lignins, allosteric inhibitors of coagulation proteinases via the heparin binding site, significantly alter the active site of thrombin and factor xa compared to heparin. Thrombosis Research. 134: 1123-9. PMID 25242245 DOI: 10.1016/j.thromres.2014.08.024  1
2014 Mehta AY, Desai UR. Substantial non-electrostatic forces are needed to induce allosteric disruption of thrombin's active site through exosite 2. Biochemical and Biophysical Research Communications. 452: 813-6. PMID 25201728 DOI: 10.1016/j.bbrc.2014.09.003  1
2014 Sankaranarayanan NV, Desai UR. Toward a robust computational screening strategy for identifying glycosaminoglycan sequences that display high specificity for target proteins. Glycobiology. 24: 1323-33. PMID 25049239 DOI: 10.1093/glycob/cwu077  1
2014 Patel NJ, Karuturi R, Al-Horani RA, Baranwal S, Patel J, Desai UR, Patel BB. Synthetic, non-saccharide, glycosaminoglycan mimetics selectively target colon cancer stem cells. Acs Chemical Biology. 9: 1826-33. PMID 24968014 DOI: 10.1021/cb500402f  1
2014 Henry BL, Desai UR. Discovery methodology for the development of direct factor VIIa inhibitors. Expert Opinion On Drug Discovery. 9: 859-72. PMID 24882057 DOI: 10.1517/17460441.2014.923398  1
2014 Al-Horani RA, Desai UR. Designing allosteric inhibitors of factor XIa. Lessons from the interactions of sulfated pentagalloylglucopyranosides. Journal of Medicinal Chemistry. 57: 4805-18. PMID 24844380 DOI: 10.1021/jm500311e  1
2014 Saluja B, Li H, Desai UR, Voelkel NF, Sakagami M. Sulfated caffeic acid dehydropolymer attenuates elastase and cigarette smoke extract-induced emphysema in rats: sustained activity and a need of pulmonary delivery. Lung. 192: 481-92. PMID 24831783 DOI: 10.1007/S00408-014-9597-2  1
2014 Argade MD, Mehta AY, Sarkar A, Desai UR. Allosteric inhibition of human factor XIa: discovery of monosulfated benzofurans as a class of promising inhibitors. Journal of Medicinal Chemistry. 57: 3559-69. PMID 24666186 DOI: 10.1021/Jm5002698  1
2014 Al-Horani RA, Desai UR. Recent advances on plasmin inhibitors for the treatment of fibrinolysis-related disorders. Medicinal Research Reviews. 34: 1168-216. PMID 24659483 DOI: 10.1002/Med.21315  1
2014 Mehta AY, Thakkar JN, Mohammed BM, Martin EJ, Brophy DF, Kishimoto T, Desai UR. Targeting the GPIbα binding site of thrombin to simultaneously induce dual anticoagulant and antiplatelet effects. Journal of Medicinal Chemistry. 57: 3030-9. PMID 24635452 DOI: 10.1021/Jm4020026  1
2014 Kalita M, Balivada S, Swarup VP, Mencio C, Raman K, Desai UR, Troyer D, Kuberan B. A nanosensor for ultrasensitive detection of oversulfated chondroitin sulfate contaminant in heparin. Journal of the American Chemical Society. 136: 554-7. PMID 24127748 DOI: 10.1021/Ja409170Z  1
2014 Mehta AY, Jin Y, Desai UR. An update on recent patents on thrombin inhibitors (2010 - 2013). Expert Opinion On Therapeutic Patents. 24: 47-67. PMID 24099091 DOI: 10.1517/13543776.2014.845169  1
2014 Safo MK, Musayev FN, Mosier PD, Zhou Q, Xie H, Desai UR. Crystal structures of influenza a virus matrix protein M1: Variations on a theme Plos One. 9. DOI: 10.1371/journal.pone.0109510  1
2014 Wood JP, Baumann Kreuziger LM, Camire RM, Desai UR, Mast AE. Relieving Inhibition of Prothrombinase By TFPIα: a Procoagulant Activity of Unfractionated, Low Molecular Weight, and Nonanticoagulant Heparins Blood. 124: 1478-1478. DOI: 10.1182/Blood.V124.21.1478.1478  0.01
2014 Patel NJ, Karuturi R, Al-Horani RA, Baranwal S, Patel J, Desai UR, Patel BB. 395 Synthetic, Non-Saccharide Glycosaminoglycan Mimetics Selectively Target Colon Cancer Stem Cells Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)60303-6  1
2013 Tarigopula S, Pokroy R, Desai UR, Ahmed SB, Goldman DJ. Surgical technique for removal of a capsular tension ring from the vitreous cavity. Retinal Cases & Brief Reports. 7: 121-2. PMID 25390800 DOI: 10.1097/ICB.0b013e31825955c5  1
2013 Desai UR. The promise of sulfated synthetic small molecules as modulators of glycosaminoglycan function. Future Medicinal Chemistry. 5: 1363-6. PMID 23919545 DOI: 10.4155/fmc.13.117  1
2013 Sidhu PS, Abdel Aziz MH, Sarkar A, Mehta AY, Zhou Q, Desai UR. Designing allosteric regulators of thrombin. Exosite 2 features multiple subsites that can be targeted by sulfated small molecules for inducing inhibition. Journal of Medicinal Chemistry. 56: 5059-70. PMID 23718540 DOI: 10.1021/Jm400369Q  1
2013 Karuturi R, Al-Horani RA, Mehta SC, Gailani D, Desai UR. Discovery of allosteric modulators of factor XIa by targeting hydrophobic domains adjacent to its heparin-binding site. Journal of Medicinal Chemistry. 56: 2415-28. PMID 23451707 DOI: 10.1021/Jm301757V  1
2013 Desai UR, Kumar N. Surgical treatment of an exudative retinal detachment associated with a giant retinal pigment epithelial tear. Ophthalmic Surgery, Lasers & Imaging Retina. 44: 97-9. PMID 23410817 DOI: 10.3928/23258160-20121221-22  1
2013 Raman K, Mencio C, Desai UR, Kuberan B. Sulfation patterns determine cellular internalization of heparin-like polysaccharides. Molecular Pharmaceutics. 10: 1442-9. PMID 23398560 DOI: 10.1021/Mp300679A  1
2013 Al-Horani RA, Ponnusamy P, Mehta AY, Gailani D, Desai UR. Sulfated pentagalloylglucoside is a potent, allosteric, and selective inhibitor of factor XIa. Journal of Medicinal Chemistry. 56: 867-78. PMID 23316863 DOI: 10.1021/Jm301338Q  1
2013 Saluja B, Thakkar JN, Li H, Desai UR, Sakagami M. Novel low molecular weight lignins as potential anti-emphysema agents: In vitro triple inhibitory activity against elastase, oxidation and inflammation. Pulmonary Pharmacology & Therapeutics. 26: 296-304. PMID 23280431 DOI: 10.1016/J.Pupt.2012.12.009  1
2013 Sidhu PS, Mosier PD, Zhou Q, Desai UR. On scaffold hopping: Challenges in the discovery of sulfated small molecules as mimetics of glycosaminoglycans Bioorganic and Medicinal Chemistry Letters. 23: 355-359. PMID 23164711 DOI: 10.1016/J.Bmcl.2012.10.079  1
2013 Xie H, Lin Z, Mosier PD, Desai UR, Gao Y. The compensatory G88R change is essential in restoring the normal functions of influenza A/WSN/33 virus matrix protein 1 with a disrupted nuclear localization signal Journal of Virology. 87: 345-353. PMID 23077315 DOI: 10.1128/Jvi.02024-12  1
2012 Mosier PD, Krishnasamy C, Kellogg GE, Desai UR. On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different. Plos One. 7: e48632. PMID 23152789 DOI: 10.1371/Journal.Pone.0048632  1
2012 Liang A, Thakkar JN, Hindle M, Desai UR. Dynamic affinity chromatography in the separation of sulfated lignins binding to thrombin. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 908: 45-51. PMID 23122400 DOI: 10.1016/J.Jchromb.2012.09.036  1
2012 Abdel Aziz MH, Sidhu PS, Liang A, Kim JY, Mosier PD, Zhou Q, Farrell DH, Desai UR. Designing allosteric regulators of thrombin. Monosulfated benzofuran dimers selectively interact with Arg173 of exosite 2 to induce inhibition Journal of Medicinal Chemistry. 55: 6888-6897. PMID 22788964 DOI: 10.1021/Jm300670Q  1
2012 Al-Horani RA, Mehta AY, Desai UR. Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold. European Journal of Medicinal Chemistry. 54: 771-83. PMID 22770607 DOI: 10.1016/J.Ejmech.2012.06.032  1
2012 Al-Horani RA, Desai UR. Electronically Rich N-Substituted Tetrahydroisoquinoline 3-Carboxylic Acid Esters: Concise Synthesis and Conformational Studies. Tetrahedron. 68: 2027-2040. PMID 22665943 DOI: 10.1016/J.Tet.2012.01.005  1
2012 Raman K, Karuturi R, Swarup VP, Desai UR, Kuberan B. Discovery of novel sulfonated small molecules that inhibit vascular tube formation. Bioorganic & Medicinal Chemistry Letters. 22: 4467-70. PMID 22627041 DOI: 10.1016/J.Bmcl.2012.04.014  1
2012 Henry BL, Thakkar JN, Liang A, Desai UR. Sulfated, low molecular weight lignins inhibit a select group of heparin-binding serine proteases. Biochemical and Biophysical Research Communications. 417: 382-6. PMID 22155248 DOI: 10.1016/J.Bbrc.2011.11.122  1
2012 Lowe Jr. EW. Recent technological advancements in ligand-based and structure-based modeling: BCL: Cheminfo and rosetta ligand Drug Designing: Open Access. 1. DOI: 10.4172/2169-0138.S1.002  0.01
2012 Blewett G, Desai UR. Failure of LP flash drum packing bed support Ammonia Plant Safety and Related Facilities. 53: 235-244.  1
2012 King JT, Desai UR. Advances in the analysis of the heparins Heparin: Properties, Uses and Side Effects. 109-132.  1
2011 Rein CM, Desai UR, Church FC. Serpin-glycosaminoglycan interactions. Methods in Enzymology. 501: 105-37. PMID 22078533 DOI: 10.1016/B978-0-12-385950-1.00007-9  1
2011 King JT, Desai UR. Linear polyalkylamines as fingerprinting agents in capillary electrophoresis of low-molecular-weight heparins and glycosaminoglycans. Electrophoresis. 32: 3070-7. PMID 22002802 DOI: 10.1002/Elps.201100175  1
2011 Abdel Aziz MH, Mosier PD, Desai UR. Identification of the site of binding of sulfated, low molecular weight lignins on thrombin Biochemical and Biophysical Research Communications. 413: 348-352. PMID 21893043 DOI: 10.1016/J.Bbrc.2011.08.102  1
2011 Pokroy R, Desai UR. Hemoglobin AC retinopathy managed with vitrectomy and adjunctive bevacizumab. Eye (London, England). 25: 1514-5. PMID 21818134 DOI: 10.1038/eye.2011.189  1
2011 Al-Horani RA, Liang A, Desai UR. Designing nonsaccharide, allosteric activators of antithrombin for accelerated inhibition of factor Xa. Journal of Medicinal Chemistry. 54: 6125-38. PMID 21800826 DOI: 10.1021/Jm2008387  1
2011 Pokroy R, Desai UR, Du E, Li Y, Edwards P. Bevacizumab prior to vitrectomy for diabetic traction retinal detachment. Eye (London, England). 25: 989-97. PMID 21738230 DOI: 10.1038/eye.2011.149  1
2011 Desai BJ, Boothello RS, Mehta AY, Scarsdale JN, Wright HT, Desai UR. Interaction of thrombin with sucrose octasulfate. Biochemistry. 50: 6973-82. PMID 21736375 DOI: 10.1021/Bi2004526  1
2011 Sidhu PS, Liang A, Mehta AY, Abdel Aziz MH, Zhou Q, Desai UR. Rational design of potent, small, synthetic allosteric inhibitors of thrombin. Journal of Medicinal Chemistry. 54: 5522-31. PMID 21714536 DOI: 10.1021/Jm2005767  1
2011 R. Desai U. Finger printing in low molecular weight heparins for regulating quality and equivalence Journal of Bioequivalence & Bioavailability. 2. DOI: 10.4172/0975-0851.1000107  0.01
2010 Raghuraman A, Mosier PD, Desai UR. Understanding Dermatan Sulfate-Heparin Cofactor II Interaction through Virtual Library Screening. Acs Medicinal Chemistry Letters. 1: 281-285. PMID 20835364 DOI: 10.1021/Ml100048Y  1
2010 Al-Horani RA, Desai UR. Chemical Sulfation of Small Molecules - Advances and Challenges. Tetrahedron. 66: 2907-2918. PMID 20689724 DOI: 10.1016/J.Tet.2010.02.015  1
2010 Pokroy R, Desai UR. Bilateral optic pit-like maculopathy with normal optic nerve heads. Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie. 45: 415-6. PMID 20436532 DOI: 10.3129/i09-269  1
2010 Thakkar JN, Tiwari V, Desai UR. Nonsulfated, cinnamic acid-based lignins are potent antagonists of HSV-1 entry into cells. Biomacromolecules. 11: 1412-6. PMID 20411926 DOI: 10.1021/Bm100161U  1
2010 Henry BL, Abdel Aziz M, Zhou Q, Desai UR. Sulfated, low-molecular-weight lignins are potent inhibitorsof plasmin, in addition to thrombin and factor Xa: Novel opportunity for controlling complex pathologies. Thrombosis and Haemostasis. 103: 507-15. PMID 20024500 DOI: 10.1160/Th09-07-0454  1
2010 Liang A, Thakkar JN, Desai UR. Study of physico-chemical properties of novel highly sulfated, aromatic, mimetics of heparin and heparan sulfate. Journal of Pharmaceutical Sciences. 99: 1207-16. PMID 19711446 DOI: 10.1002/Jps.21908  1
2010 Kaushik V, Cook N, Liang AY, Desai UR, Sidorov V. Chemoselective precipitation of lactose from a lactose/sucrose mixture: Proof of concept for a new separation methodology Supramolecular Chemistry. 22: 751-757. DOI: 10.1080/10610278.2010.500732  1
2010 Raghuraman A, Mosier PD, Desai UR. Understanding dermatan sulfate-heparin cofactor II interaction through virtual library screening Acs Medicinal Chemistry Letters. 1: 281-285. DOI: 10.1021/ml100048y  1
2010 Stevens R, Desai UR. Self-supported flare-stack vibrations in ammonia plant Process Safety Progress. 29: 254-263. DOI: 10.1002/prs.10366  1
2009 Henry BL, Thakkar JN, Martin EJ, Brophy DF, Desai UR. Characterization of the plasma and blood anticoagulant potential of structurally and mechanistically novel oligomers of 4-hydroxycinnamic acids. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 20: 27-34. PMID 20523162 DOI: 10.1097/Mbc.0B013E328304E077  1
2009 Verghese J, Liang A, Sidhu PP, Hindle M, Zhou Q, Desai UR. First steps in the direction of synthetic, allosteric, direct inhibitors of thrombin and factor Xa. Bioorganic & Medicinal Chemistry Letters. 19: 4126-9. PMID 19540113 DOI: 10.1016/J.Bmcl.2009.06.013  1
2009 Henry BL, Connell J, Liang A, Krishnasamy C, Desai UR. Interaction of antithrombin with sulfated, low molecular weight lignins: opportunities for potent, selective modulation of antithrombin function. The Journal of Biological Chemistry. 284: 20897-908. PMID 19497853 DOI: 10.1074/Jbc.M109.013359  1
2009 Liang A, Raghuraman A, Desai UR. Capillary electrophoretic study of small, highly sulfated, non-sugar molecules interacting with antithrombin. Electrophoresis. 30: 1544-51. PMID 19425011 DOI: 10.1002/Elps.200800642  1
2009 Raghuraman A, Liang A, Krishnasamy C, Lauck T, Gunnarsson GT, Desai UR. On designing non-saccharide, allosteric activators of antithrombin. European Journal of Medicinal Chemistry. 44: 2626-31. PMID 18996625 DOI: 10.1016/J.Ejmech.2008.09.042  1
2008 Krishnasamy C, Raghuraman A, Kier LB, Desai UR. Application of molecular connectivity and electro-topological indices in quantitative structure-activity analysis of pyrazole derivatives as inhibitors of factor Xa and thrombin. Chemistry & Biodiversity. 5: 2609-20. PMID 19089820 DOI: 10.1002/Cbdv.200890216  1
2008 Henry BL, Desai UR. Recent research developments in the direct inhibition of coagulation proteinases--inhibitors of the initiation phase. Cardiovascular & Hematological Agents in Medicinal Chemistry. 6: 323-36. PMID 18855645 DOI: 10.2174/187152508785909519  1
2008 King JT, Desai UR. A capillary electrophoretic method for fingerprinting low molecular weight heparins. Analytical Biochemistry. 380: 229-34. PMID 18572011 DOI: 10.1016/J.Ab.2008.05.046  1
2008 Desai UR, Bhatti RA, Khan KA, Rubowitz A. Sharp dissection of the Weiss ring to induce a posterior vitreous detachment British Journal of Ophthalmology. 92: 420-422. PMID 18303164 DOI: 10.1136/bjo.2007.124651  1
2008 Stevens R, Desai UR. Self-supported flare stack vibrations in Ammonia plant Ammonia Plant Safety and Related Facilities. 49: 17-30.  1
2007 Raghuraman A, Riaz M, Hindle M, Desai UR. Rapid and efficient microwave-assisted synthesis of highly sulfated organic scaffolds. Tetrahedron Letters. 48: 6754-6758. PMID 18797498 DOI: 10.1016/J.Tetlet.2007.07.100  1
2007 Rahman M, Riaz M, Desai UR. Synthesis of biologically relevant biflavanoids--a review. Chemistry & Biodiversity. 4: 2495-527. PMID 18027351 DOI: 10.1002/Cbdv.200790205  1
2007 Henry BL, Monien BH, Bock PE, Desai UR. A novel allosteric pathway of thrombin inhibition: Exosite II mediated potent inhibition of thrombin by chemo-enzymatic, sulfated dehydropolymers of 4-hydroxycinnamic acids. The Journal of Biological Chemistry. 282: 31891-9. PMID 17804413 DOI: 10.1074/Jbc.M704257200  1
2007 Raghuraman A, Tiwari V, Zhao Q, Shukla D, Debnath AK, Desai UR. Viral inhibition studies on sulfated lignin, a chemically modified biopolymer and a potential mimic of heparan sulfate. Biomacromolecules. 8: 1759-63. PMID 17439173 DOI: 10.1021/Bm0701651  1
2006 Monien BH, Henry BL, Raghuraman A, Hindle M, Desai UR. Novel chemo-enzymatic oligomers of cinnamic acids as direct and indirect inhibitors of coagulation proteinases. Bioorganic & Medicinal Chemistry. 14: 7988-98. PMID 16914317 DOI: 10.1016/J.Bmc.2006.07.066  1
2006 Raghuraman A, Mosier PD, Desai UR. Finding a needle in a haystack: Development of a combinatorial virtual screening approach for identifying high specificity heparin/heparan sulfate sequence(s) Journal of Medicinal Chemistry. 49: 3553-3562. PMID 16759098 DOI: 10.1021/Jm060092O  1
2006 Dhalla MS, Desai UR, Gandolfo C. Does postoperative near visual acuity predict macular hole closure? Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society For Imaging in the Eye. 37: 244-6. PMID 16749264  1
2006 Dhalla MS, Desai UR, Zuckerbrod DS. Pigmentary maculopathy in a patient with Wolfram syndrome Canadian Journal of Ophthalmology. 41: 38-40.  1
2005 Raghuraman A, Tiwari V, Thakkar JN, Gunnarsson GT, Shukla D, Hindle M, Desai UR. Structural characterization of a serendipitously discovered bioactive macromolecule, lignin sulfate. Biomacromolecules. 6: 2822-32. PMID 16153124 DOI: 10.1021/Bm0503064  1
2005 Monien BH, Krishnasamy C, Olson ST, Desai UR. Importance of tryptophan 49 of antithrombin in heparin binding and conformational activation. Biochemistry. 44: 11660-8. PMID 16128566 DOI: 10.1021/Bi050741I  1
2005 Monien BH, Cheang KI, Desai UR. Mechanism of poly(acrylic acid) acceleration of antithrombin inhibition of thrombin: implications for the design of novel heparin mimics. Journal of Medicinal Chemistry. 48: 5360-8. PMID 16078853 DOI: 10.1021/Jm0503648  1
2005 Monien BH, Desai UR. Antithrombin activation by nonsulfated, non-polysaccharide organic polymer. Journal of Medicinal Chemistry. 48: 1269-73. PMID 15715496 DOI: 10.1021/Jm0492960  1
2005 Gunnarsson GT, Riaz M, Adams J, Desai UR. Synthesis of per-sulfated flavonoids using 2,2,2-trichloro ethyl protecting group and their factor Xa inhibition potential. Bioorganic & Medicinal Chemistry. 13: 1783-9. PMID 15698795 DOI: 10.1016/J.Bmc.2004.11.060  1
2005 Schiffman RM, Jacobsen G, Nussbaum JJ, Desai UR, Carey JD, Glasser D, Zimmer-Galler IE, Zeimer R, Goldberg MF. Comparison of a digital retinal imaging system and seven-field stereo color fundus photography to detect diabetic retinopathy in the primary care environment. Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society For Imaging in the Eye. 36: 46-56. PMID 15688971  1
2005 Dantuluri M, Gunnarsson GT, Riaz M, Nguyen H, Desai UR. Capillary electrophoresis of highly sulfated flavanoids and flavonoids. Analytical Biochemistry. 336: 316-22. PMID 15620899 DOI: 10.1016/J.Ab.2004.10.017  1
2005 Desai UR. Antithrombin activation and designing novel heparin mimics Chemistry and Biology of Heparin and Heparan Sulfate. 483-512. DOI: 10.1016/B978-008044859-6/50018-6  1
2004 Khaimi MA, Samuel MA, Desai UR, Imami NR, Schiffman RM. Familial HLA-A2- and HLA-B7-associated anterior uveitis. Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie. 39: 664-6. PMID 15559654  1
2004 He X, Reeve AM, Desai UR, Kellogg GE, Reynolds KA. 1,2-dithiole-3-ones as potent inhibitors of the bacterial 3-ketoacyl acyl carrier protein synthase III (FabH). Antimicrobial Agents and Chemotherapy. 48: 3093-102. PMID 15273125 DOI: 10.1128/Aac.48.8.3093-3102.2004  1
2004 Raman SV, Desai UR, Anderson S, Samuel MA. Visual prognosis in patients with traumatic choroidal rupture. Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie. 39: 260-6. PMID 15180143  1
2004 Gunnarsson GT, Desai UR. Hydropathic interaction analyses of small organic activators binding to antithrombin. Bioorganic & Medicinal Chemistry. 12: 633-40. PMID 14738974 DOI: 10.1016/J.Bmc.2003.10.034  1
2004 Schedin-Weiss S, Desai UR, Bock SC, Olson ST, Björk I. Roles of N-terminal region residues Lys11, Arg13, and Arg24 of antithrombin in heparin recognition and in promotion and stabilization of the heparin-induced conformational change. Biochemistry. 43: 675-83. PMID 14730971 DOI: 10.1021/Bi030173B  1
2004 Desai UR. New antithrombin-based anticoagulants. Medicinal Research Reviews. 24: 151-81. PMID 14705167 DOI: 10.1002/Med.10058  1
2004 Samuel MA, Desai UR. Ocular trauma associated with Pickwickian syndrome Injury Extra. 35: 48-49. DOI: 10.1016/j.injury.2004.03.016  1
2003 Samuel MA, Desai UR, Strassman I, Abusamak M. Intraocular irrigating solutions. A clinical study of BSS Plus and dextrose bicarbonate fortified BSS as an infusate during pars plana vitrectomy. Indian Journal of Ophthalmology. 51: 237-42. PMID 14601849  1
2003 Samuel MA, Desai UR, Gandolfo CB. Peripapillary retinal detachment after radial optic neurotomy for central retinal vein occlusion. Retina (Philadelphia, Pa.). 23: 580-3. PMID 12972785 DOI: 10.1097/00006982-200308000-00033  1
2003 Desai UR, Alhalel AA, Campen TJ, Schiffman RM, Edwards PA, Jacobsen GR. Central serous chorioretinopathy in African Americans. Journal of the National Medical Association. 95: 553-9. PMID 12911253  1
2003 Gunnarsson GT, Desai UR. Exploring new non-sugar sulfated molecules as activators of antithrombin. Bioorganic & Medicinal Chemistry Letters. 13: 679-83. PMID 12639557 DOI: 10.1016/S0960-894X(02)01055-7  1
2003 Jairajpuri MA, Lu A, Desai U, Olson ST, Bjork I, Bock SC. Antithrombin III phenylalanines 122 and 121 contribute to its high affinity for heparin and its conformational activation. The Journal of Biological Chemistry. 278: 15941-50. PMID 12556442 DOI: 10.1074/Jbc.M212319200  1
2002 Anderson SK, Desai UR, Raman SV. Incidence of ocular injuries in motor vehicle crash victims with concomitant air bag deployment. Ophthalmology. 109: 2356-8. PMID 12466184 DOI: 10.1016/S0161-6420(02)01289-7  1
2002 Raja SM, Wang B, Dantuluri M, Desai UR, Demeler B, Spiegel K, Metkar SS, Froelich CJ. Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin. The Journal of Biological Chemistry. 277: 49523-30. PMID 12388539 DOI: 10.1074/Jbc.M209607200  1
2002 Gunnarsson GT, Desai UR. Interaction of designed sulfated flavanoids with antithrombin: lessons on the design of organic activators. Journal of Medicinal Chemistry. 45: 4460-70. PMID 12238925 DOI: 10.1021/Jm020132Y  1
2002 Schedin-Weiss S, Desai UR, Bock SC, Gettins PG, Olson ST, Björk I. Importance of lysine 125 for heparin binding and activation of antithrombin. Biochemistry. 41: 4779-88. PMID 11939772 DOI: 10.1021/Bi012163L  1
2002 Gunnarsson GT, Desai UR. Designing small, nonsugar activators of antithrombin using hydropathic interaction analyses. Journal of Medicinal Chemistry. 45: 1233-43. PMID 11881992 DOI: 10.1021/Jm020012Q  1
2002 Desai UR, Johns JL, Lahaye L, Wright HT. Probing reactive center loop insertion in serpins: a simple method for ovalbumin. Analytical Biochemistry. 302: 81-7. PMID 11846379 DOI: 10.1006/Abio.2001.5512  1
2001 Desai UR, Tawansy KA, Joondeph BC, Schiffman RM. Choroidal granulomas in systemic sarcoidosis Retina. 21: 40-47. PMID 11217928  1
2000 Desai UR, Raman VS, Dennehy P. Unilateral retinoschisis in fetal alcohol syndrome Retina. 20: 676-678. PMID 11131427  1
2000 Desai U, Swanson R, Bock SC, Bjork I, Olson ST. Role of arginine 129 in heparin binding and activation of antithrombin. The Journal of Biological Chemistry. 275: 18976-84. PMID 10764763 DOI: 10.1074/Jbc.M001340200  0.01
2000 Singh J, Joshi MD, Desai UR. Natural gas feed preheater fire Process Safety Progress. 19: 57-63. DOI: 10.1002/prs.680190111  1
1999 Sawant MS, Nadkarni PJ, Desai UR, Katoch R, Korde SS, Trived GK. Configurational and conformational analyses of a-methylene-γ-butyro steroidal spirolactones Journal of the Chemical Society - Perkin Transactions 1. 2537-2542. DOI: 10.1039/A902415H  1
1999 Desai UR, Gunnarsson GT. Hydropathic interaction analysis of sequence-specific heparin pentasaccharide binding to antithrombin Medicinal Chemistry Research. 9: 643-655.  1
1998 Desai UR, Petitou M, Björk I, Olson ST. Mechanism of heparin activation of antithrombin: Evidence for an induced-fit model of allosteric activation involving two interaction subsites Biochemistry. 37: 13033-13041. PMID 9737884 DOI: 10.1021/Bi981426H  1
1998 Desai UR, Petitou M, Björk I, Olson ST. Mechanism of heparin activation of antithrombin. Role of individual residues of the pentasaccharide activating sequence in the recognition of native and activated states of antithrombin Journal of Biological Chemistry. 273: 7478-7487. PMID 9516447 DOI: 10.1074/Jbc.273.13.7478  1
1998 Sawant MS, Katoch R, Trivedi GK, Desai UR. Highly stereoselective synthesis of spiro-α-methylene-γ-butyrolactones: The role of α-hydroxy substitution Journal of the Chemical Society - Perkin Transactions 1. 843-846. DOI: 10.1039/A708558C  1
1997 Desai UR, Strassman IB. Combined pars plana vitrectomy and scleral buckling for pseudophakic and aphakic retinal detachments in which a break is not seen preoperatively Ophthalmic Surgery and Lasers. 28: 718-722. PMID 9304632  1
1997 Desai UR, Alhalel AA, Schiffman RM, Campen TJ, Sundar G, Muhich A. Intraocular pressure elevation after simple pars plana vitrectomy Ophthalmology. 104: 781-786. PMID 9160023  1
1997 Strassman IB, Desai UR. Prepapillary vascular loop and a recurrent vitreous hemorrhage Retina. 17: 166-167. PMID 9143049  1
1997 Catalinn JA, Muhich AL, Fantin A, Desai UR. Age-related macular degeneration. prevalence, gender, and race. A study of 25,881 individuals seen by the henry ford eye care service in 1995 Investigative Ophthalmology and Visual Science. 38.  1
1997 Desai UR, Petitou M, Björk I, Olson ST. Role of individual saccharide residues of the heparin pentasaccharide in activation of the serpin, antithrombin Faseb Journal. 11.  1
1996 Korde SS, Baig MHA, Desai UR, Trivedi GK. Differential behavior of (25R)-5,6-epoxyspirostan-22α-O-3β-ol and (25R)-5,6-epoxyspirostan-22α-0-3β,4β-diol toward Dowex Steroids. 61: 290-295. PMID 8738833 DOI: 10.1016/0039-128X(95)00231-E  1
1996 Desai UR, Blinder KJ, Dennehy PJ. Vitrectomy and juvenile epiretinal membrane Ophthalmic Surgery and Lasers. 27: 137-139. PMID 8640437  1
1995 Liu J, Desai UR, Han XJ, Toida T, Linhardt RJ. Strategy for the sequence analysis of heparin Glycobiology. 5: 765-774. PMID 8720074 DOI: 10.1093/Glycob/5.8.765  1
1995 Desai UR, Vlahov IR, Pervin A, Linhardt RJ. Conformational analysis of sucrose octasulfate by high resolution nuclear magnetic resonance spectroscopy. Carbohydrate Research. 275: 391-401. PMID 8529231 DOI: 10.1016/0008-6215(95)00159-Q  1
1995 Desai UR. Spontaneous vitreous base avulsion in a patient with neurofibromatosis Indian Journal of Ophthalmology. 43: 33. PMID 8522370  1
1995 Desai UR, Linhardt RJ. Molecular weight of heparin using 13C nuclear magnetic resonance spectroscopy Journal of Pharmaceutical Sciences. 84: 212-215. PMID 7738804 DOI: 10.1002/Jps.2600840218  1
1995 Desai UR, Hoppensteadt D, Fareed J, Linhardt RJ. Measurement of the Antithrombin III Binding Sites in Low Molecular Weight Heparins by 13C NMR and Capillary Electrophoresis Pharmacy and Pharmacology Communications. 1: 349-353. DOI: 10.1111/J.2042-7158.1995.Tb00438.X  1
1995 Desai UR, Klibanov AM. Assessing the structural integrity of a lyophilized protein in organic solvents Journal of the American Chemical Society. 117: 3940-3945. DOI: 10.1021/Ja00119A007  1
1994 Desai UR, Linhardt RJ. Molecular weight of low molecular weight heparins by 13C nuclear magnetic resonance spectroscopy Carbohydrate Research. 255: 193-212. PMID 8181007 DOI: 10.1016/S0008-6215(00)90979-0  1
1994 Linhardt RJ, Desai UR, Liu J, Pervin A, Hoppensteadt D, Fareed J. Low molecular weight dermatan sulfate as an antithrombotic agent. Structure-activity relationship studies. Biochemical Pharmacology. 47: 1241-52. PMID 8161353 DOI: 10.1016/0006-2952(94)90396-4  1
1994 Bae J, Desai UR, Pervin A, Caldwell EE, Weiler JM, Linhardt RJ. Interaction of heparin with synthetic antithrombin III peptide analogues. The Biochemical Journal. 301: 121-9. PMID 8037658 DOI: 10.1042/Bj3010121  1
1994 Liu J, Pervin A, Gallo CM, Desai UR, Van Gorp CL, Linhardt RJ. New approaches for the preparation of hydrophobic heparin derivatives. Journal of Pharmaceutical Sciences. 83: 1034-9. PMID 7965660 DOI: 10.1002/Jps.2600830721  1
1994 Desai UR, Osterhout JJ, Klibanov AM. Protein structure in the lyophilized state: A hydrogen isotope exchange/NMR study with bovine pancreatic trypsin inhibitor Journal of the American Chemical Society. 116: 9420-9422. DOI: 10.1021/Ja00100A002  1
1993 Sridharan R, Desai UR, Rao RM, Trivedi GK. Conformational analysis of A and B rings in 2-, 4-, and 6-bromosubstituted steroidal 4-en-3-ones by nuclear magnetic resonance. Steroids. 58: 170-7. PMID 8493706 DOI: 10.1016/0039-128X(93)90064-T  1
1993 Desai UR, Wang HM, Kelly TR, Linhardt RJ. Structure elucidation of a novel acidic tetrasaccharide and hexasaccharide derived from a chemically modified heparin. Carbohydrate Research. 241: 249-59. PMID 8472255 DOI: 10.1016/0008-6215(93)80112-R  1
1993 Desai UR, Sudhamathi K, Natarajan S. Intravenous Epinephrine and Acute Macular Neuroretinopathy Archives of Ophthalmology. 111: 1026-1027. PMID 8352681 DOI: 10.1001/archopht.1993.01090080022009  1
1993 Desai UR, Wang HM, Linhardt RJ. Specificity studies on the heparin lyases from Flavobacterium heparinum Biochemistry. 32: 8140-8145. PMID 8347612 DOI: 10.1021/Bi00083A012  1
1993 Schulman JA, Peyman GA, Blinder KJ, Alturki WA, Desai UR, Nelson NC. Management of giant retinal tears with perfluoroperhydrophenanthrene (Vitreon). Japanese Journal of Ophthalmology. 37: 70-7. PMID 8320868  1
1993 Desai UR, Wang H, Ampofo SA, Linhardt RJ. Oligosaccharide composition of heparin and low-molecular-weight heparins by capillary electrophoresis Analytical Biochemistry. 213: 120-127. PMID 8238864 DOI: 10.1006/Abio.1993.1394  1
1993 Desai UR, Peyman GA, Harper CA. Perfluorocarbon liquid in traumatic vitreous hemorrhage and retinal detachment Ophthalmic Surgery. 24: 537-541. PMID 8233318  1
1993 Desai UR, Wang H, Linhardt RJ. Substrate specificity of the heparin lyases from Flavobacterium heparinum Archives of Biochemistry and Biophysics. 306: 461-468. PMID 8215450 DOI: 10.1006/Abbi.1993.1538  1
1993 Peyman GA, Nelson NC, Blinder KJ, Alturki WA, Desai UR, Paris CL. Autologous transplantation of retinal pigment epithelial (RPE) cells Afro-Asian Journal of Ophthalmology. 11: 237-244.  1
1992 Desai UR, Peyman GA, Blinder KJ, Alturki WA, Paris CL, Nelson NC. Orbital extension of sinus lymphoma in AIDS patient Japanese Journal of Ophthalmology. 36: 205-214. PMID 1513068  1
1992 Lee KJ, Peyman GA, Paris CL, Alturki WA, Desai UR. Management of retinal detachment associated with choroidal coloboma using perfluoroperhydrophenanthrene (Vitreon®) Ophthalmic Surgery. 23: 553-554. PMID 1508487  1
1992 Peyman GA, Nelson NC, Paris CL, Blinder KJ, Alturki WA, Desai UR. Internal choroidectomy of posterior uveal melanomas under a retinal flap International Ophthalmology. 16: 439-444. PMID 1490835 DOI: 10.1007/BF00918434  1
1992 Desai UR, Peyman GA, Chen CJ, Nelson NC, Alturki WA, Blinder KJ, Paris CL. Use of perfluoroperhydrophenanthrene in the management of suprachoroidal hemorrhages Ophthalmology. 99: 1542-1547. PMID 1454320  1
1992 Lee KB, Desai UR, Palcic MM, Hindsgaul O, Linhardt RJ. An electrophoresis-based assay for glycosyltransferase activity Analytical Biochemistry. 205: 108-114. PMID 1443547 DOI: 10.1016/0003-2697(92)90586-V  1
1992 Alturki WA, Peyman GA, Paris CL, Blinder KJ, Desai UR, Nelson NC. Posterior relaxing retinotomies: Analysis of anatomic and visual results Ophthalmic Surgery. 23: 685-688. PMID 1436968  1
1992 Blinder KJ, Peyman GA, Desai UR, Nelson NC, Alturki W, Paris CL. Vitreon, a short-term vitreoretinal tamponade British Journal of Ophthalmology. 76: 525-528. PMID 1420054 DOI: 10.1136/bjo.76.9.525  1
1992 Banerjee S, Desai UR, Trivedi GK. Synthesis of 2'-(3α-benzyloxy-24-norcholan-23-yl)-2',4',4'-trimethyl- 4',5'-dihydrooxazoline-n-oxyl - a new potential spin probe for biomembranes Tetrahedron. 48: 133-148. DOI: 10.1016/S0040-4020(01)80586-X  1
1991 Peyman GA, Nelson NC, Alturki W, Blinder KJ, Paris CL, Desai UR, Harper CA. Tissue plasminogen activating factor assisted removal of subretinal hemorrhage Ophthalmic Surgery. 22: 575-582. PMID 1961614  1
1991 Desai UR, Trivedi GK. New steroid haptens for radioimmunoassay: Synthesis of steroids substituted with thioether or ester linkages at the 2α-position Steroids. 56: 185-188. PMID 1871783 DOI: 10.1016/0039-128X(91)90080-F  1
1991 Banerjee S, Desai UR, Trivedi GK. On the protection of 3α-hydroxy group of a/b cis steroids Synthetic Communications. 21: 757-770. DOI: 10.1080/00397919108019755  1
1991 Desai UR, Trivedi GK. Conformational analysis of ring A and total assignment of 19-functionalized 4-en-3-one steroids. Applicability of 2D NOE as a crucial technique Journal of Organic Chemistry. 56: 4625-4631. DOI: 10.1021/Jo00015A012  1
1990 Desai UR, Sabates FN. Long-term follow-up of facioscapulohumeral muscular dystrophy and Coats' disease American Journal of Ophthalmology. 110: 568-569. PMID 2240145  1
1990 Desai UR, Sawant MS, Trivedi GK. New steroid haptens for radioimmunoassay part II. synthesis of thioether based haptens for testosterone Synthetic Communications. 20: 2423-2438. DOI: 10.1080/00397919008053190  1
1990 Subramanian S, Desai UR, Trivedi GK. Reductive alkylation of nitrochromenes. synthesis of spiro-[n-hydroxy] -lactams# Synthetic Communications. 20: 1733-1742. DOI: 10.1080/00397919008053097  1
Show low-probability matches.