Martin Friedlander - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Cell Biology, Molecular Biology, Biochemistry

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lim EW, Fallon RJ, Bates C, Ideguchi Y, Nagasaki T, Handzlik MK, Joulia E, Bonelli R, Green CR, Ansell BRE, Kitano M, Polis I, Roberts AJ, Furuya S, Allikmets R, ... ... Friedlander M, et al. Serine and glycine physiology reversibly modulate retinal and peripheral nerve function. Cell Metabolism. PMID 39191258 DOI: 10.1016/j.cmet.2024.07.021  0.338
2023 Marra KV, Chen JS, Robles-Holmes HK, Miller J, Wei G, Aguilar E, Ideguchi Y, Ly KB, Prenner S, Erdogmus D, Ferrara N, Campbell JP, Friedlander M, Nudleman E. Development of a Semi-automated Computer-based Tool for the Quantification of Vascular Tortuosity in the Murine Retina. Ophthalmology Science. 4: 100439. PMID 38361912 DOI: 10.1016/j.xops.2023.100439  0.388
2023 Chen JS, Marra KV, Robles-Holmes HK, Ly KB, Miller J, Wei G, Aguilar E, Bucher F, Ideguchi Y, Coyner AS, Ferrara N, Campbell JP, Friedlander M, Nudleman E. Applications of Deep Learning: Automated Assessment of Vascular Tortuosity in Mouse Models of Oxygen-Induced Retinopathy. Ophthalmology Science. 4: 100338. PMID 37869029 DOI: 10.1016/j.xops.2023.100338  0.338
2023 Rosarda JD, Giles S, Harkins-Perry S, Mills EA, Friedlander M, Wiseman RL, Eade KT. Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity. Nature Communications. 14: 4119. PMID 37433773 DOI: 10.1038/s41467-023-39775-w  0.315
2023 Usui-Ouchi A, Giles S, Harkins-Perry S, Mills EA, Bonelli R, Wei G, Ouchi Y, Ebihara N, Nakao S, Friedlander M, Eade KT. Integrating human iPSC-derived macrophage progenitors into retinal organoids to generate a mature retinal microglial niche. Glia. PMID 37335016 DOI: 10.1002/glia.24428  0.401
2023 Eade KT, Ansell BRE, Giles S, Fallon R, Harkins-Perry S, Nagasaki T, Tzaridis S, Wallace M, Mills EA, Farashi S, Johnson A, Sauer L, Hart B, Rubio ED, Bahlo M, ... ... Friedlander M, et al. iPSC-derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function. The Journal of Clinical Investigation. 133. PMID 37115691 DOI: 10.1172/JCI163771  0.322
2022 Marra KV, Aguilar E, Guoqin W, Usui-Ouchi A, Ideguchi Y, Sakimoto S, Friedlander M. Bioactive extracellular vesicles from a subset of endothelial progenitor cells rescue retinal ischemia and neurodegeneration. Jci Insight. PMID 35639473 DOI: 10.1172/jci.insight.155928  0.347
2022 Usui-Ouchi A, Eade K, Giles S, Ideguchi Y, Ouchi Y, Aguilar E, Wei G, Marra KV, Berlow RB, Friedlander M. Deletion of Tgfβ signal in activated microglia prolongs hypoxia-induced retinal neovascularization enhancing Igf1 expression and retinal leukostasis. Glia. PMID 35611927 DOI: 10.1002/glia.24218  0.379
2022 Thomas ED, Timms AE, Giles S, Harkins-Perry S, Lyu P, Hoang T, Qian J, Jackson VE, Bahlo M, Blackshaw S, Friedlander M, Eade K, Cherry TJ. Cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease in human retina and retinal organoids. Developmental Cell. PMID 35303433 DOI: 10.1016/j.devcel.2022.02.018  0.348
2021 Jung I, Jung D, Zha Z, Jeong J, Noh S, Shin J, Park JK, Kim KS, Jeong Y, Hur J, Baek MC, Diaz-Aguilar S, Aguilar E, Friedlander M, Bucher F, et al. Interferon-γ inhibits retinal neovascularization in a mouse model of ischemic retinopathy. Cytokine. 155542. PMID 33926775 DOI: 10.1016/j.cyto.2021.155542  0.417
2021 Eade K, Gantner ML, Hostyk JA, Nagasaki T, Giles S, Fallon R, Harkins-Perry S, Baldini M, Lim EW, Scheppke L, Dorrell MI, Cai C, Baugh EH, Wolock CJ, Wallace M, ... ... Friedlander M, et al. Serine biosynthesis defect due to haploinsufficiency of PHGDH causes retinal disease. Nature Metabolism. 3: 366-377. PMID 33758422 DOI: 10.1038/s42255-021-00361-3  0.721
2021 Eade K, Giles S, Harkins-Perry S, Friedlander M. Toxicity Screens in Human Retinal Organoids for Pharmaceutical Discovery. Journal of Visualized Experiments : Jove. PMID 33749682 DOI: 10.3791/62269  0.356
2021 Bonelli R, Jackson VE, Prasad A, Munro JE, Farashi S, Heeren TFC, Pontikos N, Scheppke L, Friedlander M, Egan CA, Allikmets R, Ansell BRE, Bahlo M. Identification of genetic factors influencing metabolic dysregulation and retinal support for MacTel, a retinal disorder. Communications Biology. 4: 274. PMID 33654266 DOI: 10.1038/s42003-021-01788-w  0.32
2020 Usui-Ouchi A, Aguilar E, Murinello S, Prins M, Gantner ML, Wright PE, Berlow RB, Friedlander M. An allosteric peptide inhibitor of HIF-1α regulates hypoxia-induced retinal neovascularization. Proceedings of the National Academy of Sciences of the United States of America. PMID 33106407 DOI: 10.1073/pnas.2017234117  0.357
2020 Bucher F, Aguilar E, Marra KV, Rapp J, Arnold J, Diaz-Aguilar S, Lange C, Agostini H, Schlunck G, Stahl A, Friedlander M. CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10. Investigative Ophthalmology & Visual Science. 61: 20. PMID 32780864 DOI: 10.1167/Iovs.61.10.20  0.491
2020 Bonelli R, Woods SM, Ansell BRE, Heeren TFC, Egan CA, Khan KN, Guymer R, Trombley J, Friedlander M, Bahlo M, Fruttiger M. Systemic lipid dysregulation is a risk factor for macular neurodegenerative disease. Scientific Reports. 10: 12165. PMID 32699277 DOI: 10.1038/S41598-020-69164-Y  0.343
2020 Usui-Ouchi A, Usui Y, Kurihara T, Aguilar E, Dorrell MI, Ideguchi Y, Sakimoto S, Bravo S, Friedlander M. Retinal microglia are critical for subretinal neovascular formation. Jci Insight. PMID 32437334 DOI: 10.1172/Jci.Insight.137317  0.781
2019 Gantner ML, Eade K, Wallace M, Handzlik MK, Fallon R, Trombley J, Bonelli R, Giles S, Harkins-Perry S, Heeren TFC, Sauer L, Ideguchi Y, Baldini M, Scheppke L, Dorrell MI, ... ... Friedlander M, et al. Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy. The New England Journal of Medicine. PMID 31509666 DOI: 10.1056/Nejmoa1815111  0.705
2019 Usui-Ouchi A, Friedlander M. Anti-VEGF therapy: higher potency and long-lasting antagonism are not necessarily better. The Journal of Clinical Investigation. 130. PMID 31232702 DOI: 10.1172/Jci129862  0.327
2019 Bucher F, Friedlander MSH, Aguilar E, Kurihara T, Krohne TU, Usui Y, Friedlander M. The long dystrophin gene product Dp427 modulates retinal function and vascular morphology in response to age and retinal ischemia. Neurochemistry International. 129: 104489. PMID 31199961 DOI: 10.1016/J.Neuint.2019.104489  0.497
2019 Murinello S, Usui Y, Sakimoto S, Kitano M, Aguilar E, Friedlander HM, Schricker A, Wittgrove C, Wakabayashi Y, Dorrell MI, Westenskow PD, Friedlander M. miR-30a-5p inhibition promotes interaction of Fas endothelial cells and FasL microglia to decrease pathological neovascularization and promote physiological angiogenesis. Glia. 67: 332-344. PMID 30484883 DOI: 10.1002/Glia.23543  0.735
2018 Laíns I, Gantner M, Murinello S, Lasky-Su JA, Miller JW, Friedlander M, Husain D. Metabolomics in the study of retinal health and disease. Progress in Retinal and Eye Research. PMID 30423446 DOI: 10.1016/J.Preteyeres.2018.11.002  0.406
2018 Chew EY, Clemons TE, Jaffe GJ, Johnson CA, Farsiu S, Lad EM, Guymer R, Rosenfeld P, Hubschman JP, Constable I, Wiley H, Singerman LJ, Gillies M, Comer G, ... ... Friedlander M, et al. Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2: A Randomized Clinical Trial. Ophthalmology. PMID 30292541 DOI: 10.1016/J.Ophtha.2018.09.041  0.403
2018 Hacibekiroglu S, Michael I, Mitrousis N, Yang H, Massumi M, Vawda R, Ballios B, Westenskow P, Friedlander M, van der Kooy D, Shoichet M, Nagy A. Combined cell and gene therapy towards the treatment of age-related macular degeneration and diabetic retinopathy Cytotherapy. 20: S19. DOI: 10.1016/J.Jcyt.2018.02.040  0.327
2017 Mukherjee D, Lad EM, Vann RR, Jaffe SJ, Clemons TE, Friedlander M, Chew EY, Jaffe GJ, Farsiu S. Correlation Between Macular Integrity Assessment and Optical Coherence Tomography Imaging of Ellipsoid Zone in Macular Telangiectasia Type 2. Investigative Ophthalmology & Visual Science. 58: BIO291-BIO299. PMID 28973315 DOI: 10.1167/Iovs.17-21834  0.347
2017 Levin LA, Miller JW, Zack DJ, Friedlander M, Smith LE. Special Commentary: Early Clinical Development of Cell Replacement Therapy: Considerations for the National Eye Institute Audacious Goals Initiative. Ophthalmology. PMID 28365209 DOI: 10.1016/J.Ophtha.2017.02.017  0.391
2017 Bucher F, Zhang D, Aguilar E, Sakimoto S, Diaz-Aguilar S, Rosenfeld M, Zha Z, Zhang H, Friedlander M, Yea K. Antibody-Mediated Inhibition of Tspan12 Ameliorates Vasoproliferative Retinopathy Through Suppression of β-Catenin Signaling. Circulation. PMID 28356444 DOI: 10.1161/Circulationaha.116.025604  0.457
2017 Scerri TS, Quaglieri A, Cai C, Zernant J, Matsunami N, Baird L, Scheppke L, Bonelli R, Yannuzzi LA, Friedlander M, Egan CA, Fruttiger M, Leppert M, Allikmets R, et al. Genome-wide analyses identify common variants associated with macular telangiectasia type 2. Nature Genetics. PMID 28250457 DOI: 10.1038/Ng.3799  0.319
2017 Sakimoto S, Marchetti V, Aguilar E, Lee K, Usui Y, Murinello S, Bucher F, Trombley JK, Fallon R, Wagey R, Peters C, Scheppke EL, Westenskow PD, Friedlander M. CD44 expression in endothelial colony-forming cells regulates neurovascular trophic effect. Jci Insight. 2: e89906. PMID 28138561 DOI: 10.1172/Jci.Insight.89906  0.545
2016 Keir LS, Firth R, Aponik L, Feitelberg D, Sakimoto S, Aguilar E, Welsh GI, Richards A, Usui Y, Satchell SC, Kuzmuk V, Coward RJ, Goult J, Bull KR, Sharma R, ... ... Friedlander M, et al. VEGF regulates local inhibitory complement proteins in the eye and kidney. The Journal of Clinical Investigation. PMID 27918307 DOI: 10.1172/Jci86418  0.527
2016 Barnett FH, Rosenfeld M, Wood M, Kiosses WB, Usui Y, Marchetti V, Aguilar E, Friedlander M. Macrophages form functional vascular mimicry channels in vivo. Scientific Reports. 6: 36659. PMID 27834402 DOI: 10.1038/Srep36659  0.42
2016 Murinello S, Moreno SK, Macauley MS, Sakimoto S, Westenskow PD, Friedlander M. Assessing Retinal Microglial Phagocytic Function In Vivo Using a Flow Cytometry-based Assay. Journal of Visualized Experiments : Jove. PMID 27805590 DOI: 10.3791/54677  0.393
2016 Wang J, Westenskow PD, Fang M, Friedlander M, Siuzdak G. Quantitative metabolomics of photoreceptor degeneration and the effects of stem cell-derived retinal pigment epithelium transplantation. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 374. PMID 27644974 DOI: 10.1098/Rsta.2015.0376  0.45
2016 Bucher F, Walz JM, Bühler A, Aguilar E, Lange C, Diaz-Aguilar S, Martin G, Schlunck G, Agostini H, Friedlander M, Stahl A. CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy. Investigative Ophthalmology & Visual Science. 57: 4017-4026. PMID 27494343 DOI: 10.1167/Iovs.15-18508  0.525
2016 Joyal JS, Sun Y, Gantner ML, Shao Z, Evans LP, Saba N, Fredrick T, Burnim S, Kim JS, Patel G, Juan AM, Hurst CG, Hatton CJ, Cui Z, Pierce KA, ... ... Friedlander M, et al. Corrigendum: Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1. Nature Medicine. 22: 692. PMID 27270778 DOI: 10.1038/Nm0616-692A  0.306
2016 Kurihara T, Westenskow PD, Gantner ML, Usui Y, Schultz A, Bravo S, Aguilar E, Wittgrove C, Friedlander MS, Paris LP, Chew E, Siuzdak G, Friedlander M. Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration. Elife. 5. PMID 26978795 DOI: 10.7554/Elife.14319  0.466
2016 Joyal JS, Sun Y, Gantner ML, Shao Z, Evans LP, Saba N, Fredrick T, Burnim S, Kim JS, Patel G, Juan AM, Hurst CG, Hatton CJ, Cui Z, Pierce KA, ... ... Friedlander M, et al. Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1. Nature Medicine. PMID 26974308 DOI: 10.1038/Nm.4059  0.382
2016 Westenskow PD, Bucher F, Bravo S, Kurihara T, Feitelberg D, Paris LP, Aguilar E, Lin JH, Friedlander M. iPSC-Derived Retinal Pigment Epithelium Allografts Do Not Elicit Detrimental Effects in Rats: A Follow-Up Study. Stem Cells International. 2016: 8470263. PMID 26880994 DOI: 10.1155/2016/8470263  0.456
2016 Paris LP, Johnson CH, Aguilar E, Usui Y, Cho K, Hoang LT, Feitelberg D, Benton HP, Westenskow PD, Kurihara T, Trombley J, Tsubota K, Ueda S, Wakabayashi Y, Patti GJ, ... ... Friedlander M, et al. Global metabolomics reveals metabolic dysregulation in ischemic retinopathy. Metabolomics : Official Journal of the Metabolomic Society. 12: 15. PMID 26617478 DOI: 10.1007/S11306-015-0877-5  0.303
2016 Kurihara T, Westenskow PD, Gantner ML, Usui Y, Schultz A, Bravo S, Aguilar E, Wittgrove C, Friedlander MS, Paris LP, Chew E, Siuzdak G, Friedlander M. Author response: Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration Elife. DOI: 10.7554/Elife.14319.030  0.413
2015 Usui Y, Westenskow PD, Murinello S, Dorrell MI, Scheppke L, Bucher F, Sakimoto S, Paris LP, Aguilar E, Friedlander M. Angiogenesis and Eye Disease. Annual Review of Vision Science. 1: 155-184. PMID 28532369 DOI: 10.1146/annurev-vision-082114-035439  0.781
2015 Zhao T, Zhang ZN, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M, Clegg DO, Yang YG, Zhang K, Friedlander M, Xu Y. Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. Cell Stem Cell. 17: 353-9. PMID 26299572 DOI: 10.1016/J.Stem.2015.07.021  0.368
2015 Usui Y, Westenskow PD, Kurihara T, Aguilar E, Sakimoto S, Paris LP, Wittgrove C, Feitelberg D, Friedlander MS, Moreno SK, Dorrell MI, Friedlander M. Neurovascular crosstalk between interneurons and capillaries is required for vision. The Journal of Clinical Investigation. 125: 2335-46. PMID 25915585 DOI: 10.1172/Jci80297  0.779
2015 Westenskow P, Sedillo Z, Barnett A, Friedlander M. Efficient derivation of retinal pigment epithelium cells from stem cells. Journal of Visualized Experiments : Jove. PMID 25867641 DOI: 10.3791/52214  0.466
2015 Westenskow PD, Kurihara T, Bravo S, Feitelberg D, Sedillo ZA, Aguilar E, Friedlander M. Performing subretinal injections in rodents to deliver retinal pigment epithelium cells in suspension. Journal of Visualized Experiments : Jove. 52247. PMID 25651341 DOI: 10.3791/52247  0.45
2014 Michael IP, Westenskow PD, Hacibekiroglu S, Greenwald AC, Ballios BG, Kurihara T, Li Z, Warren CM, Zhang P, Aguilar E, Donaldson L, Marchetti V, Baba T, Hussein SM, Sung HK, ... ... Friedlander M, et al. Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye. Embo Molecular Medicine. 6: 604-23. PMID 24705878 DOI: 10.1002/Emmm.201303708  0.473
2014 Westenskow PD, Kurihara T, Friedlander M. Utilizing stem cell-derived RPE cells as a therapeutic intervention for age-related macular degeneration. Advances in Experimental Medicine and Biology. 801: 323-9. PMID 24664714 DOI: 10.1007/978-1-4614-3209-8_41  0.451
2014 Kurihara T, Westenskow PD, Friedlander M. Hypoxia-inducible factor (HIF)/vascular endothelial growth factor (VEGF) signaling in the retina. Advances in Experimental Medicine and Biology. 801: 275-81. PMID 24664708 DOI: 10.1007/978-1-4614-3209-8_35  0.517
2013 Westenskow PD, Kurihara T, Aguilar E, Scheppke EL, Moreno SK, Wittgrove C, Marchetti V, Michael IP, Anand S, Nagy A, Cheresh D, Friedlander M. Ras pathway inhibition prevents neovascularization by repressing endothelial cell sprouting. The Journal of Clinical Investigation. 123: 4900-8. PMID 24084735 DOI: 10.1172/Jci70230  0.494
2013 Kurihara T, Westenskow PD, Aguilar E, Friedlander M. VEGF antagonism and age-related macular degeneration: Too much of a good thing? Expert Review of Ophthalmology. 8: 103-105. DOI: 10.1586/Eop.13.6  0.388
2012 Kurihara T, Westenskow PD, Bravo S, Aguilar E, Friedlander M. Targeted deletion of Vegfa in adult mice induces vision loss. The Journal of Clinical Investigation. 122: 4213-7. PMID 23093773 DOI: 10.1172/Jci65157  0.564
2012 Westenskow PD, Moreno SK, Krohne TU, Kurihara T, Zhu S, Zhang ZN, Zhao T, Xu Y, Ding S, Friedlander M. Using flow cytometry to compare the dynamics of photoreceptor outer segment phagocytosis in iPS-derived RPE cells. Investigative Ophthalmology & Visual Science. 53: 6282-90. PMID 22871841 DOI: 10.1167/Iovs.12-9721  0.379
2012 Friedlander M. Advances in treatment and management: immunologic and cell-based regenerative therapies. Investigative Ophthalmology & Visual Science. 53: 2511-4. PMID 22562853 DOI: 10.1167/Iovs.12-9483P  0.43
2012 Krohne TU, Westenskow PD, Kurihara T, Friedlander DF, Lehmann M, Dorsey AL, Li W, Zhu S, Schultz A, Wang J, Siuzdak G, Ding S, Friedlander M. Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells. Stem Cells Translational Medicine. 1: 96-109. PMID 22532929 DOI: 10.5966/Sctm.2011-0057  0.38
2011 Marchetti V, Yanes O, Aguilar E, Wang M, Friedlander D, Moreno S, Storm K, Zhan M, Naccache S, Nemerow G, Siuzdak G, Friedlander M. Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy. Scientific Reports. 1: 76. PMID 22355595 DOI: 10.1038/Srep00076  0.404
2011 Kurihara T, Westenskow PD, Krohne TU, Aguilar E, Johnson RS, Friedlander M. Astrocyte pVHL and HIF-α isoforms are required for embryonic-to-adult vascular transition in the eye. The Journal of Cell Biology. 195: 689-701. PMID 22084310 DOI: 10.1083/Jcb.201107029  0.48
2010 Marchetti V, Krohne TU, Friedlander DF, Friedlander M. Stemming vision loss with stem cells. The Journal of Clinical Investigation. 120: 3012-21. PMID 20811157 DOI: 10.1172/Jci42951  0.418
2010 Weidemann A, Krohne TU, Aguilar E, Kurihara T, Takeda N, Dorrell MI, Simon MC, Haase VH, Friedlander M, Johnson RS. Astrocyte hypoxic response is essential for pathological but not developmental angiogenesis of the retina. Glia. 58: 1177-85. PMID 20544853 DOI: 10.1002/Glia.20997  0.787
2010 Dorrell MI, Aguilar E, Jacobson R, Trauger SA, Friedlander J, Siuzdak G, Friedlander M. Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy. Glia. 58: 43-54. PMID 19544395 DOI: 10.1002/Glia.20900  0.802
2009 Friedlander M. Combination angiostatic therapies: targeting multiple angiogenic pathways. Retina (Philadelphia, Pa.). 29: S27-9. PMID 19553794 DOI: 10.1097/Iae.0B013E3181Ad2673  0.38
2009 Dorrell MI, Aguilar E, Jacobson R, Yanes O, Gariano R, Heckenlively J, Banin E, Ramirez GA, Gasmi M, Bird A, Siuzdak G, Friedlander M. Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress. The Journal of Clinical Investigation. 119: 611-23. PMID 19188685 DOI: 10.1172/Jci35977  0.78
2008 Aguilar E, Dorrell MI, Friedlander D, Jacobson RA, Johnson A, Marchetti V, Moreno SK, Ritter MR, Friedlander M. Chapter 6. Ocular models of angiogenesis. Methods in Enzymology. 444: 115-58. PMID 19007663 DOI: 10.1016/S0076-6879(08)02806-1  0.786
2008 Scheppke L, Aguilar E, Gariano RF, Jacobson R, Hood J, Doukas J, Cao J, Noronha G, Yee S, Weis S, Martin MB, Soll R, Cheresh DA, Friedlander M. Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits. The Journal of Clinical Investigation. 118: 2337-46. PMID 18483622 DOI: 10.1172/Jci33361  0.524
2007 Ritter MR, Butschek RA, Friedlander M, Friedlander SF. Pathogenesis of infantile haemangioma: new molecular and cellular insights. Expert Reviews in Molecular Medicine. 9: 1-19. PMID 18045510 DOI: 10.1017/S146239940700052X  0.368
2007 Friedlander M, Dorrell MI, Ritter MR, Marchetti V, Moreno SK, El-Kalay M, Bird AC, Banin E, Aguilar E. Progenitor cells and retinal angiogenesis. Angiogenesis. 10: 89-101. PMID 17372851 DOI: 10.1007/S10456-007-9070-4  0.79
2007 Uusitalo-Jarvinen H, Kurokawa T, Mueller BM, Andrade-Gordon P, Friedlander M, Ruf W. Role of protease activated receptor 1 and 2 signaling in hypoxia-induced angiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1456-62. PMID 17363687 DOI: 10.1161/Atvbaha.107.142539  0.346
2007 Friedlander M. Fibrosis and diseases of the eye. The Journal of Clinical Investigation. 117: 576-86. PMID 17332885 DOI: 10.1172/Jci31030  0.44
2007 Dorrell M, Uusitalo-Jarvinen H, Aguilar E, Friedlander M. Ocular neovascularization: basic mechanisms and therapeutic advances. Survey of Ophthalmology. 52: S3-19. PMID 17240254 DOI: 10.1016/J.Survophthal.2006.10.017  0.794
2007 Dorrell MI, Aguilar E, Scheppke L, Barnett FH, Friedlander M. Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 967-72. PMID 17210921 DOI: 10.1073/Pnas.0607542104  0.722
2006 Ritter MR, Banin E, Moreno SK, Aguilar E, Dorrell MI, Friedlander M. Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy. The Journal of Clinical Investigation. 116: 3266-76. PMID 17111048 DOI: 10.1172/Jci29683  0.791
2006 Lutty GA, Chan-Ling T, Phelps DL, Adamis AP, Berns KI, Chan CK, Cole CH, D'Amore PA, Das A, Deng WT, Dobson V, Flynn JT, Friedlander M, Fulton A, Good WV, et al. Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California). Molecular Vision. 12: 532-80. PMID 16735995  0.338
2006 Banin E, Dorrell MI, Aguilar E, Ritter MR, Aderman CM, Smith AC, Friedlander J, Friedlander M. T2-TrpRS inhibits preretinal neovascularization and enhances physiological vascular regrowth in OIR as assessed by a new method of quantification. Investigative Ophthalmology & Visual Science. 47: 2125-34. PMID 16639024 DOI: 10.1167/Iovs.05-1096  0.762
2006 Dorrell MI, Friedlander M. Mechanisms of endothelial cell guidance and vascular patterning in the developing mouse retina. Progress in Retinal and Eye Research. 25: 277-95. PMID 16515881 DOI: 10.1016/J.Preteyeres.2006.01.001  0.787
2006 Jin H, Aiyer A, Su J, Borgstrom P, Stupack D, Friedlander M, Varner J. A homing mechanism for bone marrow-derived progenitor cell recruitment to the neovasculature. The Journal of Clinical Investigation. 116: 652-62. PMID 16498499 DOI: 10.1172/Jci24751  0.378
2006 Ritter MR, Reinisch J, Friedlander SF, Friedlander M. Myeloid cells in infantile hemangioma. The American Journal of Pathology. 168: 621-8. PMID 16436675 DOI: 10.2353/Ajpath.2006.050618  0.332
2005 Friedlander SF, Ritter MR, Friedlander M. Recent progress in our understanding of the pathogenesis of infantile hemangiomas. Lymphatic Research and Biology. 3: 219-25. PMID 16379591 DOI: 10.1089/Lrb.2005.3.219  0.31
2005 Ritter MR, Aguilar E, Banin E, Scheppke L, Uusitalo-Jarvinen H, Friedlander M. Three-dimensional in vivo imaging of the mouse intraocular vasculature during development and disease. Investigative Ophthalmology & Visual Science. 46: 3021-6. PMID 16123396 DOI: 10.1167/Iovs.05-0153  0.485
2005 Otani A, Friedlander M. Retinal vascular regeneration. Seminars in Ophthalmology. 20: 43-50. PMID 15804843 DOI: 10.1080/08820530590921891  0.492
2004 Otani A, Dorrell MI, Kinder K, Moreno SK, Nusinowitz S, Banin E, Heckenlively J, Friedlander M. Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineage-negative hematopoietic stem cells. The Journal of Clinical Investigation. 114: 765-74. PMID 15372100 DOI: 10.1172/Jci21686  0.787
2004 Belting M, Dorrell MI, Sandgren S, Aguilar E, Ahamed J, Dorfleutner A, Carmeliet P, Mueller BM, Friedlander M, Ruf W. Regulation of angiogenesis by tissue factor cytoplasmic domain signaling. Nature Medicine. 10: 502-9. PMID 15098027 DOI: 10.1038/Nm1037  0.724
2004 Dorrell MI, Aguilar E, Weber C, Friedlander M. Global gene expression analysis of the developing postnatal mouse retina. Investigative Ophthalmology & Visual Science. 45: 1009-19. PMID 14985324 DOI: 10.1167/Iovs.03-0806  0.71
2004 Dorrell MI, Otani A, Aguilar E, Moreno SK, Friedlander M. Adult bone marrow-derived stem cells use R-cadherin to target sites of neovascularization in the developing retina. Blood. 103: 3420-7. PMID 14726407 DOI: 10.1182/Blood-2003-09-3012  0.762
2003 Ritter MR, Moreno SK, Dorrell MI, Rubens J, Ney J, Friedlander DF, Bergman J, Cunningham BB, Eichenfield L, Reinisch J, Cohen S, Veccione T, Holmes R, Friedlander SF, Friedlander M. Identifying potential regulators of infantile hemangioma progression through large-scale expression analysis: a possible role for the immune system and indoleamine 2,3 dioxygenase (IDO) during involution. Lymphatic Research and Biology. 1: 291-9. PMID 15624557 DOI: 10.1089/153968503322758094  0.713
2003 Heckenlively JR, Hawes NL, Friedlander M, Nusinowitz S, Hurd R, Davisson M, Chang B. Mouse model of subretinal neovascularization with choroidal anastomosis. Retina (Philadelphia, Pa.). 23: 518-22. PMID 12972764 DOI: 10.1097/00006982-200308000-00012  0.493
2003 Aguilar E, Friedlander M, Gariano RF. Endothelial proliferation in diabetic retinal microaneurysms. Archives of Ophthalmology. 121: 740-1. PMID 12742861 DOI: 10.1001/Archopht.121.5.740  0.44
2003 Von Seggern DJ, Aguilar E, Kinder K, Fleck SK, Gonzalez Armas JC, Stevenson SC, Ghazal P, Nemerow GR, Friedlander M. In vivo transduction of photoreceptors or ciliary body by intravitreal injection of pseudotyped adenoviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 27-34. PMID 12573615 DOI: 10.1016/S1525-0016(02)00030-8  0.322
2002 Dorrell MI, Aguilar E, Friedlander M. Retinal vascular development is mediated by endothelial filopodia, a preexisting astrocytic template and specific R-cadherin adhesion. Investigative Ophthalmology & Visual Science. 43: 3500-10. PMID 12407162 DOI: 10.1007/978-3-540-29542-6_2  0.777
2002 Otani A, Kinder K, Ewalt K, Otero FJ, Schimmel P, Friedlander M. Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis. Nature Medicine. 8: 1004-10. PMID 12145646 DOI: 10.1038/Nm744  0.537
2002 Ritter MR, Dorrell MI, Edmonds J, Friedlander SF, Friedlander M. Insulin-like growth factor 2 and potential regulators of hemangioma growth and involution identified by large-scale expression analysis. Proceedings of the National Academy of Sciences of the United States of America. 99: 7455-60. PMID 12032304 DOI: 10.1073/Pnas.102185799  0.73
2002 Otani A, Slike BM, Dorrell MI, Hood J, Kinder K, Ewalt KL, Cheresh D, Schimmel P, Friedlander M. A fragment of human TrpRS as a potent antagonist of ocular angiogenesis. Proceedings of the National Academy of Sciences of the United States of America. 99: 178-83. PMID 11773625 DOI: 10.1073/Pnas.012601899  0.768
2001 Summers RG, Aguilar E, Leonard M, Friedlander M. The Use of Multidimensional Microscopy in the Characterization of Retinal Vascular Development in a Murine Model Microscopy and Microanalysis. 7: 1010-1011. DOI: 10.1017/S1431927600031123  0.503
1998 Brooks PC, Silletti S, von Schalscha TL, Friedlander M, Cheresh DA. Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Cell. 92: 391-400. PMID 9476898 DOI: 10.1097/00006982-199805000-00037  0.383
1996 Friedlander M, Theesfeld CL, Sugita M, Fruttiger M, Thomas MA, Chang S, Cheresh DA. Involvement of integrins αvβ3 and αvβ5 in ocular neovascular diseases Proceedings of the National Academy of Sciences of the United States of America. 93: 9764-9769. PMID 8790405 DOI: 10.1073/Pnas.93.18.9764  0.541
1995 Friedlander M, Brooks PC, Shaffer RW, Kincaid CM, Varner JA, Cheresh DA. Definition of two angiogenic pathways by distinct alpha v integrins. Science (New York, N.Y.). 270: 1500-2. PMID 7491498 DOI: 10.1126/Science.270.5241.1500  0.343
1980 Friedlander M. Immunological approaches to the study of myogenesis and lens fiber junction formation Current Topics in Developmental Biology. 14: 321-358. PMID 7006927 DOI: 10.1016/S0070-2153(08)60200-8  0.301
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