Angie Rizzino - Publications

Affiliations: 
University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Molecular Biology, Biochemistry

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Year Citation  Score
2022 Metz EP, Wilder PJ, Popay TM, Wang J, Liu Q, Kalluchi A, Rowley MJ, Tansey WP, Rizzino A. Elevating SOX2 Downregulates MYC through a SOX2:MYC Signaling Axis and Induces a Slowly Cycling Proliferative State in Human Tumor Cells. Cancers. 14. PMID 35454854 DOI: 10.3390/cancers14081946  0.352
2020 Metz EP, Wuebben EL, Wilder PJ, Cox JL, Datta K, Coulter D, Rizzino A. Tumor quiescence: elevating SOX2 in diverse tumor cell types downregulates a broad spectrum of the cell cycle machinery and inhibits tumor growth. Bmc Cancer. 20: 941. PMID 32998722 DOI: 10.1186/s12885-020-07370-7  0.503
2019 Metz EP, Wilder PJ, Dong J, Datta K, Rizzino A. Elevating SOX2 in prostate tumor cells upregulates expression of neuroendocrine genes, but does not reduce the inhibitory effects of enzalutamide. Journal of Cellular Physiology. PMID 31587305 DOI: 10.1002/Jcp.29267  0.456
2019 Metz EP, Rizzino A. Sox2 dosage: A critical determinant in the functions of Sox2 in both normal and tumor cells. Journal of Cellular Physiology. 234: 19298-19306. PMID 31344986 DOI: 10.1002/Jcp.28610  0.413
2017 Wuebben EL, Rizzino A. The dark side of SOX2: cancer - a comprehensive overview. Oncotarget. PMID 28388544 DOI: 10.18632/Oncotarget.16570  0.407
2016 Teotia P, Chopra DA, Dravid SM, Van Hook MJ, Qiu F, Morrison J, Rizzino A, Ahmad I. Generation of Functional Human Retinal Ganglion Cells with Target Specificity from Pluripotent Stem Cells by Chemically Defined Recapitulation of Developmental Mechanism. Stem Cells (Dayton, Ohio). PMID 27709736 DOI: 10.1002/Stem.2513  0.43
2016 Wuebben EL, Wilder PJ, Cox JL, Grunkemeyer JA, Caffrey T, Hollingsworth MA, Rizzino A. SOX2 functions as a molecular rheostat to control the growth, tumorigenicity and drug responses of pancreatic ductal adenocarcinoma cells. Oncotarget. PMID 27145457 DOI: 10.18632/Oncotarget.8994  0.618
2016 Haney SL, Upchurch GM, Opavska J, Klinkebiel D, Hlady RA, Suresh A, Pirruccello SJ, Shukla V, Lu R, Costinean S, Rizzino A, Karpf AR, Joshi S, Swanson P, Opavsky R. Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a. Cell Reports. PMID 27134162 DOI: 10.1016/J.Celrep.2016.04.004  0.354
2016 Rizzino A, Wuebben EL. Sox2/Oct4: A delicately balanced partnership in pluripotent stem cells and embryogenesis. Biochimica Et Biophysica Acta. PMID 26992828 DOI: 10.1016/J.Bbagrm.2016.03.006  0.53
2016 Wuebben EL, Wilder PJ, Rizzino A. Abstract LB-280: SOX2 functions as a molecular rheostat to control the growth, tumorigenicity, and chemosensitivity of pancreatic ductal adenocarcinoma cells Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-280  0.41
2014 Cox JL, Wilder PJ, Wuebben EL, Ouellette MM, Hollingsworth MA, Rizzino A. Context-dependent function of the deubiquitinating enzyme USP9X in pancreatic ductal adenocarcinoma. Cancer Biology & Therapy. 15: 1042-52. PMID 24841553 DOI: 10.4161/Cbt.29182  0.59
2014 Shrivastava T, Mino K, Babayeva ND, Baranovskaya OI, Rizzino A, Tahirov TH. Structural basis of Ets1 activation by Runx1 Leukemia. DOI: 10.1038/Leu.2014.111  0.388
2013 Ormsbee Golden BD, Wuebben EL, Rizzino A. Sox2 expression is regulated by a negative feedback loop in embryonic stem cells that involves AKT signaling and FoxO1. Plos One. 8: e76345. PMID 24116102 DOI: 10.1371/Journal.Pone.0076345  0.812
2013 Cox JL, Wilder PJ, Gilmore JM, Wuebben EL, Washburn MP, Rizzino A. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. Plos One. 8: e62857. PMID 23667531 DOI: 10.1371/Journal.Pone.0062857  0.535
2013 Rizzino A. Concise review: The Sox2-Oct4 connection: critical players in a much larger interdependent network integrated at multiple levels. Stem Cells (Dayton, Ohio). 31: 1033-9. PMID 23401375 DOI: 10.1002/stem.1352  0.455
2012 Cox JL, Wilder PJ, Desler M, Rizzino A. Elevating SOX2 levels deleteriously affects the growth of medulloblastoma and glioblastoma cells. Plos One. 7: e44087. PMID 22937156 DOI: 10.1371/Journal.Pone.0044087  0.649
2012 Wuebben EL, Mallanna SK, Cox JL, Rizzino A. Musashi2 is required for the self-renewal and pluripotency of embryonic stem cells. Plos One. 7: e34827. PMID 22496868 DOI: 10.1371/Journal.Pone.0034827  0.824
2012 Yusuf D, Butland SL, Swanson MI, Bolotin E, Ticoll A, Cheung WA, Zhang XY, Dickman CT, Fulton DL, Lim JS, Schnabl JM, Ramos OH, Vasseur-Cognet M, de Leeuw CN, Simpson EM, ... ... Rizzino A, et al. The transcription factor encyclopedia. Genome Biology. 13: R24. PMID 22458515 DOI: 10.1186/Gb-2012-13-3-R24  0.75
2012 Gao Z, Cox JL, Gilmore JM, Ormsbee BD, Mallanna SK, Washburn MP, Rizzino A. Determination of protein interactome of transcription factor Sox2 in embryonic stem cells engineered for inducible expression of four reprogramming factors. The Journal of Biological Chemistry. 287: 11384-97. PMID 22334693 DOI: 10.1074/Jbc.M111.320143  0.81
2012 Mallanna SK, Rizzino A. Systems biology provides new insights into the molecular mechanisms that control the fate of embryonic stem cells. Journal of Cellular Physiology. 227: 27-34. PMID 21412766 DOI: 10.1002/Jcp.22721  0.801
2011 Ji M, Rao E, Ramachandrareddy H, Shen Y, Jiang C, Chen J, Hu Y, Rizzino A, Chan WC, Fu K, McKeithan TW. The miR-17-92 microRNA cluster is regulated by multiple mechanisms in B-cell malignancies. The American Journal of Pathology. 179: 1645-56. PMID 21806958 DOI: 10.1016/j.ajpath.2011.06.008  0.339
2011 Cox JL, Mallanna SK, Ormsbee BD, Desler M, Wiebe MS, Rizzino A. Banf1 is required to maintain the self-renewal of both mouse and human embryonic stem cells. Journal of Cell Science. 124: 2654-65. PMID 21750191 DOI: 10.1242/Dev.072223  0.83
2011 Chakravarthy H, Ormsbee BD, Mallanna SK, Rizzino A. Rapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machinery. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 206-18. PMID 20876214 DOI: 10.1096/Fj.10-166926  0.831
2010 Cox JL, Mallanna SK, Luo X, Rizzino A. Sox2 uses multiple domains to associate with proteins present in Sox2-protein complexes. Plos One. 5: e15486. PMID 21103394 DOI: 10.1371/Journal.Pone.0015486  0.793
2010 Rizzino A. Stimulating progress in regenerative medicine: improving the cloning and recovery of cryopreserved human pluripotent stem cells with ROCK inhibitors. Regenerative Medicine. 5: 799-807. PMID 20868334 DOI: 10.2217/Rme.10.45  0.401
2010 Mallanna SK, Ormsbee BD, Iacovino M, Gilmore JM, Cox JL, Kyba M, Washburn MP, Rizzino A. Proteomic analysis of Sox2-associated proteins during early stages of mouse embryonic stem cell differentiation identifies Sox21 as a novel regulator of stem cell fate. Stem Cells (Dayton, Ohio). 28: 1715-27. PMID 20687156 DOI: 10.1002/Stem.494  0.839
2010 Babayeva ND, Wilder PJ, Shiina M, Mino K, Desler M, Ogata K, Rizzino A, Tahirov TH. Structural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNA. Cell Cycle (Georgetown, Tex.). 9: 3054-62. PMID 20686355 DOI: 10.4161/Cc.9.14.12257  0.376
2010 Ramachandrareddy H, Bouska A, Shen Y, Ji M, Rizzino A, Chan WC, McKeithan TW. BCL6 promoter interacts with far upstream sequences with greatly enhanced activating histone modifications in germinal center B cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 11930-5. PMID 20547840 DOI: 10.1073/Pnas.1004962107  0.475
2010 Mallanna SK, Rizzino A. Emerging roles of microRNAs in the control of embryonic stem cells and the generation of induced pluripotent stem cells. Developmental Biology. 344: 16-25. PMID 20478297 DOI: 10.1016/J.Ydbio.2010.05.014  0.744
2010 Cox JL, Rizzino A. Induced pluripotent stem cells: what lies beyond the paradigm shift. Experimental Biology and Medicine (Maywood, N.J.). 235: 148-58. PMID 20404029 DOI: 10.1258/Ebm.2009.009267  0.559
2010 Agarkar VB, Babayeva ND, Wilder PJ, Rizzino A, Tahirov TH. Crystal structure of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA. Journal of Molecular Biology. 397: 278-89. PMID 20079749 DOI: 10.1016/J.Jmb.2010.01.017  0.365
2010 Zhang Q, Triplett AA, Harms DW, Lin WC, Creamer BA, Rizzino A, Wagner KU. Temporally and spatially controlled expression of transgenes in embryonic and adult tissues. Transgenic Research. 19: 499-509. PMID 19821046 DOI: 10.1007/S11248-009-9329-1  0.451
2009 Agarkar VB, Babayeva ND, Rizzino A, Tahirov TH. Preliminary crystallographic analysis of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 1261-3. PMID 20054123 DOI: 10.1107/S1744309109038007  0.4
2009 Rizzino A. Sox2 and Oct-3/4: a versatile pair of master regulators that orchestrate the self-renewal and pluripotency of embryonic stem cells. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 1: 228-36. PMID 20016762 DOI: 10.1002/Wsbm.12  0.532
2009 Wilder PJ, Chakravarthy H, Hollingsworth MA, Rizzino A. Comparison of ras-responsive gene enhancers in pancreatic tumor cells that express either wild-type or mutant K-ras. Biochemical and Biophysical Research Communications. 381: 706-11. PMID 19254697 DOI: 10.1016/J.Bbrc.2009.02.126  0.742
2009 Claassen DA, Desler MM, Rizzino A. ROCK inhibition enhances the recovery and growth of cryopreserved human embryonic stem cells and human induced pluripotent stem cells. Molecular Reproduction and Development. 76: 722-32. PMID 19235204 DOI: 10.1002/Mrd.21021  0.814
2009 Boer B, Cox JL, Claassen D, Mallanna SK, Desler M, Rizzino A. Regulation of the Nanog gene by both positive and negative cis-regulatory elements in embryonal carcinoma cells and embryonic stem cells. Molecular Reproduction and Development. 76: 173-82. PMID 18537119 DOI: 10.1002/Mrd.20943  0.804
2008 Chakravarthy H, Boer B, Desler M, Mallanna SK, McKeithan TW, Rizzino A. Identification of DPPA4 and other genes as putative Sox2:Oct-3/4 target genes using a combination of in silico analysis and transcription-based assays. Journal of Cellular Physiology. 216: 651-62. PMID 18366076 DOI: 10.1002/Jcp.21440  0.813
2008 Rizzino A. Transcription factors that behave as master regulators during mammalian embryogenesis function as molecular rheostats. The Biochemical Journal. 411: e5-7. PMID 18363551 DOI: 10.1042/Bj20080479  0.521
2008 Kopp JL, Ormsbee BD, Desler M, Rizzino A. Small increases in the level of Sox2 trigger the differentiation of mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 26: 903-11. PMID 18238855 DOI: 10.1634/Stemcells.2007-0951  0.8
2008 Mallanna SK, Boer B, Desler M, Rizzino A. Differential regulation of the Oct-3/4 gene in cell culture model systems that parallel different stages of mammalian development. Molecular Reproduction and Development. 75: 1247-57. PMID 18213644 DOI: 10.1002/Mrd.20871  0.858
2007 Rizzino A. A challenge for regenerative medicine: proper genetic programming, not cellular mimicry. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 236: 3199-207. PMID 17685475 DOI: 10.1002/Dvdy.21285  0.463
2007 Boer B, Kopp J, Mallanna S, Desler M, Chakravarthy H, Wilder PJ, Bernadt C, Rizzino A. Elevating the levels of Sox2 in embryonal carcinoma cells and embryonic stem cells inhibits the expression of Sox2:Oct-3/4 target genes. Nucleic Acids Research. 35: 1773-86. PMID 17324942 DOI: 10.1093/Nar/Gkm059  0.809
2007 Kopp JL, Wilder PJ, Desler M, Kinarsky L, Rizzino A. Different domains of the transcription factor ELF3 are required in a promoter-specific manner and multiple domains control its binding to DNA. The Journal of Biological Chemistry. 282: 3027-41. PMID 17148437 DOI: 10.1074/Jbc.M609907200  0.693
2006 Boer B, Bernadt CT, Desler M, Wilder PJ, Kopp JL, Rizzino A. Differential activity of the FGF-4 enhancer in F9 and P19 embryonal carcinoma cells. Journal of Cellular Physiology. 208: 97-108. PMID 16523502 DOI: 10.1002/Jcp.20635  0.819
2006 Neve RM, Parmar H, Amend C, Chen C, Rizzino A, Benz CC. Identification of an epithelial-specific enhancer regulating ESX expression. Gene. 367: 118-25. PMID 16307850 DOI: 10.1016/j.gene.2005.10.001  0.458
2005 Bernadt CT, Nowling T, Wiebe MS, Rizzino A. NF-Y behaves as a bifunctional transcription factor that can stimulate or repress the FGF-4 promoter in an enhancer-dependent manner. Gene Expression. 12: 193-212. PMID 16128003 DOI: 10.3727/000000005783992052  0.842
2005 Boer B, Luster TA, Bernadt C, Rizzino A. Distal enhancer of the mouse FGF-4 gene and its human counterpart exhibit differential activity: critical role of a GT box. Molecular Reproduction and Development. 71: 263-74. PMID 15803454 DOI: 10.1002/Mrd.20264  0.821
2004 Hou J, Wilder PJ, Bernadt CT, Boer B, Neve RM, Rizzino A. Transcriptional regulation of the murine Elf3 gene in embryonal carcinoma cells and their differentiated counterparts: requirement for a novel upstream regulatory region. Gene. 340: 123-31. PMID 15556300 DOI: 10.1016/J.Gene.2004.06.007  0.849
2004 Bernadt CT, Nowling T, Rizzino A. Transcription factor Sox-2 inhibits co-activator stimulated transcription. Molecular Reproduction and Development. 69: 260-7. PMID 15349837 DOI: 10.1002/Mrd.20168  0.829
2004 Kopp JL, Wilder PJ, Desler M, Kim JH, Hou J, Nowling T, Rizzino A. Unique and selective effects of five Ets family members, Elf3, Ets1, Ets2, PEA3, and PU.1, on the promoter of the type II transforming growth factor-beta receptor gene. The Journal of Biological Chemistry. 279: 19407-20. PMID 14976186 DOI: 10.1074/Jbc.M314115200  0.754
2003 Luster TA, Rizzino A. Regulation of the FGF-4 gene by a complex distal enhancer that functions in part as an enhanceosome. Gene. 323: 163-72. PMID 14659890 DOI: 10.1016/J.Gene.2003.09.019  0.824
2003 Ge B, Li O, Wilder P, Rizzino A, McKeithan TW. NF-kappa B regulates BCL3 transcription in T lymphocytes through an intronic enhancer. Journal of Immunology (Baltimore, Md. : 1950). 171: 4210-8. PMID 14530344 DOI: 10.4049/Jimmunol.171.8.4210  0.498
2003 Bernadt CT, Rizzino A. Roles of the conserved CCAAT and GC boxes of the human and mouse type II transforming growth factor-beta receptor genes. Molecular Reproduction and Development. 65: 353-65. PMID 12840808 DOI: 10.1002/Mrd.10313  0.769
2003 Wiebe MS, Nowling TK, Rizzino A. Identification of novel domains within Sox-2 and Sox-11 involved in autoinhibition of DNA binding and partnership specificity. The Journal of Biological Chemistry. 278: 17901-11. PMID 12637543 DOI: 10.1074/Jbc.M212211200  0.777
2003 Nowling T, Bernadt C, Johnson L, Desler M, Rizzino A. The co-activator p300 associates physically with and can mediate the action of the distal enhancer of the FGF-4 gene. The Journal of Biological Chemistry. 278: 13696-705. PMID 12488456 DOI: 10.1074/Jbc.M207567200  0.783
2002 Nowling T, Desler M, Kuszynski C, Rizzino A. Transfection of embryonal carcinoma cells at high efficiency using liposome-mediated transfection. Molecular Reproduction and Development. 63: 309-17. PMID 12237946 DOI: 10.1002/Mrd.90014  0.402
2002 Wilder PJ, Bernadt CT, Kim JH, Rizzino A. Stimulation of the murine type II transforming growth factor-beta receptor promoter by the transcription factor Egr-1. Molecular Reproduction and Development. 63: 282-90. PMID 12237943 DOI: 10.1002/Mrd.10165  0.767
2002 Karan D, Kelly DL, Rizzino A, Lin MF, Batra SK. Expression profile of differentially-regulated genes during progression of androgen-independent growth in human prostate cancer cells. Carcinogenesis. 23: 967-75. PMID 12082018 DOI: 10.1093/Carcin/23.6.967  0.303
2002 Rizzino A. Embryonic stem cells provide a powerful and versatile model system. Vitamins and Hormones. 64: 1-42. PMID 11898389 DOI: 10.1016/S0083-6729(02)64001-4  0.528
2002 Kim JH, Wilder PJ, Hou J, Nowling T, Rizzino A. Activation of the murine type II transforming growth factor-beta receptor gene: up-regulation and function of the transcription factor Elf-3/Ert/Esx/Ese-1. The Journal of Biological Chemistry. 277: 17520-30. PMID 11893733 DOI: 10.1074/Jbc.M110434200  0.525
2002 Johnson LR, Johnson TK, Desler M, Luster TA, Nowling T, Lewis RE, Rizzino A. Effects of B-Myb on gene transcription: phosphorylation-dependent activity ans acetylation by p300. The Journal of Biological Chemistry. 277: 4088-97. PMID 11733503 DOI: 10.1074/Jbc.M105112200  0.765
2001 Kingsley-Kallesen M, Luster TA, Rizzino A. Transcriptional regulation of the transforming growth factor-beta2 gene in glioblastoma cells. In Vitro Cellular & Developmental Biology. Animal. 37: 684-90. PMID 11776974 DOI: 10.1290/1071-2690(2001)037<0684:Trottg>2.0.Co;2  0.802
2000 Luster TA, Johnson LR, Nowling TK, Lamb KA, Philipsen S, Rizzino A. Behavior of M-phase synchronized blastomeres after nuclear transfer in cattle Molecular Reproduction and Development. 57: 37-47. PMID 10954854  0.73
2000 Luster TA, Johnson LR, Nowling TK, Lamb KA, Philipsen S, Rizzino A. Effects of three Sp1 motifs on the transcription of the FGF-4 gene. Molecular Reproduction and Development. 57: 4-15. PMID 10954851 DOI: 10.1002/1098-2795(200009)57:1<4::Aid-Mrd3>3.0.Co;2-I  0.817
2000 Kelly DL, Rizzino A. DNA microarray analyses of genes regulated during the differentiation of embryonic stem cells Molecular Reproduction and Development. 56: 113-123. PMID 10813842 DOI: 10.1002/(SICI)1098-2795(200006)56:2<113::AID-MRD1>3.0.CO;2-Q  0.486
2000 Wiebe MS, Wilder PJ, Kelly D, Rizzino A. Isolation, characterization, and differential expression of the murine Sox-2 promoter. Gene. 246: 383-93. PMID 10767561 DOI: 10.1016/S0378-1119(00)00086-X  0.818
2000 Nowling TK, Johnson LR, Wiebe MS, Rizzino A. Identification of the transactivation domain of the transcription factor Sox-2 and an associated co-activator. The Journal of Biological Chemistry. 275: 3810-8. PMID 10660531 DOI: 10.1074/Jbc.275.6.3810  0.797
1999 Kingsley-Kallesen ML, Kelly D, Rizzino A. Transcriptional regulation of the transforming growth factor-β2 promoter by cAMP-responsive element-binding protein (CREB) and activating transcription factor-1 (ATF-1) is modulated by protein kinases and the coactivators p300 and CREB-binding protein Journal of Biological Chemistry. 274: 34020-34028. PMID 10567368 DOI: 10.1074/jbc.274.48.34020  0.403
1999 Chiang Y, Rizzino A, Sibenaller ZA, Wold MS, Vishwanatha JK. Specific down-regulation of annexin II expression in human cells interferes with cell proliferation. Molecular and Cellular Biochemistry. 199: 139-47. PMID 10544962 DOI: 10.1023/A:1006942128672  0.31
1999 Xie W, Wilder PJ, Stribley J, Chatonnet A, Rizzino A, Taylor P, Hinrichs SH, Lockridge O. Knockout of one acetylcholinesterase allele in the mouse Chemico-Biological Interactions. 119: 289-299. PMID 10421464 DOI: 10.1016/S0009-2797(99)00039-3  0.357
1998 Lamb KA, Rizzino A. Effects of differentiation on the transcriptional regulation of the FGF- 4 gene: Critical roles played by a distal enhancer Molecular Reproduction and Development. 51: 218-224. PMID 9740330 DOI: 10.1002/(SICI)1098-2795(199810)51:2<218::AID-MRD12>3.0.CO;2-0  0.54
1998 Kelly D, Kim SJ, Rizzino A. Transcriptional activation of the type II transforming growth factor-β receptor gene upon differentiation of embryonal carcinoma cells Journal of Biological Chemistry. 273: 21115-21124. PMID 9694866 DOI: 10.1074/jbc.273.33.21115  0.48
1998 Johnson LR, Lamb KA, Gao Q, Nowling TK, Rizzino A. Role of the transcription factor Sox-2 in the expression of the FGF-4 gene in embryonal carcinoma cells. Molecular Reproduction and Development. 50: 377-86. PMID 9669521 DOI: 10.1002/(Sici)1098-2795(199808)50:4<377::Aid-Mrd1>3.0.Co;2-F  0.598
1997 Wilder PJ, Kelly D, Brigman K, Peterson CL, Nowling T, Gao QS, McComb RD, Capecchi MR, Rizzino A. Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny. Developmental Biology. 192: 614-29. PMID 9441693 DOI: 10.1006/Dbio.1997.8777  0.486
1997 Lamb KA, Johnson LR, Rizzino A. NF-Y binds to the CCAAT box motif of the FGF-4 gene and promotes FGF-4 expression in embryonal carcinoma cells. Molecular Reproduction and Development. 48: 301-9. PMID 9322240 DOI: 10.1002/(SICI)1098-2795(199711)48:3<301::AID-MRD1>3.0.CO;2-V  0.518
1997 Kingsley-Kallesen M, Johnson L, Scholtz B, Kelly D, Rizzino A. Transcriptional regulation of the TGF-β2 gene in choriocarcinoma cells and breast carcinoma cells: Differential utilization of cis-regulatory elements In Vitro Cellular and Developmental Biology - Animal. 33: 294-301. PMID 9156346  0.489
1996 Lickteig K, Lamb K, Brigman K, Rizzino A. Effects of oxidation and reduction on the binding of transcription factors to cis-regulatory elements located in the FGF-4 gene Molecular Reproduction and Development. 44: 146-152. PMID 9115711 DOI: 10.1002/(Sici)1098-2795(199606)44:2<146::Aid-Mrd2>3.0.Co;2-N  0.51
1996 Miller K, Rizzino A. Characterization of fibroblast growth factor activity secreted by embryonal carcinoma cells In Vitro Cellular and Developmental Biology - Animal. 32: 531-533. PMID 8946224 DOI: 10.1007/Bf02722979  0.395
1996 Scholtz B, Kingsley-Kallesen M, Rizzino A. Transcription of the transforming growth factor-β2 gene is dependent on an E-box located between an essential cAMP response element/activating transcription factor motif and the TATA box of the gene Journal of Biological Chemistry. 271: 32375-32380. PMID 8943301 DOI: 10.1074/Jbc.271.50.32375  0.503
1996 Lamb K, Rosfjord E, Brigman K, Rizzino A. Binding of transcription factors to widely-separated cis-regulatory elements of the murine FGF-4 gene Molecular Reproduction and Development. 44: 460-471. PMID 8844688 DOI: 10.1002/(Sici)1098-2795(199608)44:4<460::Aid-Mrd5>3.0.Co;2-J  0.818
1996 Miller K, Rizzino A. Constitutive expression of fibroblast growth factor-4 does not alter the growth or the differentiation of embryonal carcinoma cells Cell Growth and Differentiation. 7: 203-211. PMID 8822204  0.447
1996 Scholtz B, Lamb K, Rosfjord E, Kingsley M, Rizzino A. Appearance of nuclear protease activity after embryonal carcinoma cells undergo differentiation Developmental Biology. 173: 420-427. PMID 8606002 DOI: 10.1006/Dbio.1996.0037  0.798
1995 Kelly D, Scholtz B, Orten DJ, Hinrichs SH, Rizzino A. Regulation of the transforming growth factor-β2 gene promoter in embryonal carcinoma cells and their differentiated cells: Differential utilization of transcription factors Molecular Reproduction and Development. 40: 135-145. PMID 7766406 DOI: 10.1002/mrd.1080400202  0.442
1995 Miller K, Rizzino A. The Function of Inducible Promoter Systems in F9 Embryonal Carcinoma Cells Experimental Cell Research. 218: 144-150. PMID 7737354 DOI: 10.1006/Excr.1995.1141  0.572
1995 Scholtz B, Kelly D, Rizzino A. Cis-regulatory elements and transcription factors involved in the regulation of the transforming growth factor-β2 gene Molecular Reproduction and Development. 41: 140-148. PMID 7654367 DOI: 10.1002/mrd.1080410204  0.433
1995 Rosfjord E, Scholtz B, Lewis R, Rizzino A. Phosphorylation and DNA Binding of the Octamer Binding Transcription Factor OCT-3 Biochemical and Biophysical Research Communications. 212: 847-853. PMID 7626120 DOI: 10.1006/Bbrc.1995.2046  0.693
1994 Rizzino A, Rosfjord E. Transcriptional regulation of the murine k-fgf gene Molecular Reproduction and Development. 39: 106-111. PMID 7999355 DOI: 10.1002/Mrd.1080390116  0.797
1994 Rosfjord E, Lamb K, Rizzino A. Cryptic promoter activity within the backbone of a plasmid commonly used to prepare promoter/reporter gene constructs In Vitro Cellular &Amp; Developmental Biology - Animal. 30: 477-481. PMID 7952517 DOI: 10.1007/Bf02631317  0.789
1994 Rosfjord E, Rizzino A. The Octamer Motif Present in the Rex-1 Promoter Binds Oct-1 and Oct-3 Expressed by EC Cells and ES Cells Biochemical and Biophysical Research Communications. 203: 1795-1802. PMID 7945330 DOI: 10.1006/Bbrc.1994.2395  0.782
1993 Kuszynski CA, Miller KA, Rizzino A. Influence of cell density and receptor number on the binding and distribution of cell surface epidermal growth factor receptors In Vitro Cellular &Amp; Developmental Biology - Animal: Journal of the Society For in Vitro Biology. 29: 708-713. PMID 8407714 DOI: 10.1007/Bf02631427  0.36
1993 Hirota M, Egami H, Corra S, Fujii H, Chaney WG, Rizzino A, Pour PM. Production of scatter factor-like activity by a nitrosamine-induced pancreatic cancer cell line. Carcinogenesis. 14: 259-64. PMID 8382114 DOI: 10.1093/Carcin/14.2.259  0.387
1993 Miller K, Wilder PJ, Rizzino A. Fibroblast growth factor complexed to the cytotoxin saporin is growth inhibitory but not cytotoxic for embryonal carcinoma cells Cytotechnology. 13: 69-78. PMID 7764580 DOI: 10.1007/Bf00749933  0.42
1992 Kelly D, O'Reilly MA, Rizzino A. Differential regulation of the transforming growth factor type-β2 gene promoter in embryonal carcinoma cells and their differentiated cells Developmental Biology. 153: 172-175. PMID 1516748 DOI: 10.1016/0012-1606(92)90102-M  0.388
1992 Ma YG, Rosfjord E, Huebert C, Wilder P, Tiesman J, Kelly D, Rizzino A. Transcriptional regulation of the murine k-FGF gene in embryonic cell lines Developmental Biology. 154: 45-54. PMID 1426633 DOI: 10.1016/0012-1606(92)90046-J  0.765
1992 Campbell WJ, Miller KA, Anderson TM, Shull JD, Rizzino A. Expression of fibroblast growth factor receptors by embryonal carcinoma cells and early mouse embryos. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 28: 61-6. PMID 1370443 DOI: 10.1007/Bf02631080  0.533
1991 Rizzino A, Huebert C, Kuszynski C, Wilder PJ. Effects of cell density and phorbol esters on the expression of epidermal growth factor receptors Cytotechnology. 7: 85-92. PMID 1367910 DOI: 10.1007/Bf00350914  0.375
1990 Rizzino A, Kazakoff P, Nebelsick J. Density-induced down regulation of epidermal growth factor receptors In Vitro Cellular and Developmental Biology - Animal. 26: 537-542. PMID 2351645 DOI: 10.1007/Bf02624098  0.388
1989 Kelly D, Rizzino A. Inhibitory effects of transforming growth factor-β on laminin production and growth exhibited by endoderm-like cells derived from embryonal carcinoma cells Differentiation. 41: 34-41. PMID 2806770 DOI: 10.1111/J.1432-0436.1989.Tb00729.X  0.321
1989 Tiesman J, Rizzino A. Expression and developmental regulation of the k-FGF oncogene in human and murine embryonal carcinoma cells In Vitro Cellular &Amp; Developmental Biology. 25: 1193-1198. PMID 2481673 DOI: 10.1007/BF02621274  0.389
1989 Tiesman J, Rizzino A. Recent developments in the structure, function and regulation of platelet-derived growth factor and its receptors Cytotechnology. 2: 333-350. DOI: 10.1007/Bf00364997  0.382
1988 Tiesman J, Meyer A, Hines RN, Rizzino A. Production of growth factors related to fibroblast growth factor and platelet-derived growth factor by human embryonal carcinoma cells In Vitro Cellular &Amp; Developmental Biology. 24: 1209-1216. PMID 3209587 DOI: 10.1007/Bf02624192  0.315
1988 Rizzino A, Kuszynski C, Ruff E, Tiesman J. Production and utilization of growth factors related to fibroblast growth factor by embryonal carcinoma cells and their differentiated cells Developmental Biology. 129: 61-71. PMID 2842210 DOI: 10.1016/0012-1606(88)90161-3  0.449
1986 Rizzino A, Ruff E. Fibroblast growth factor induces the soft agar growth of two non-transformed cell lines In Vitro Cellular and Developmental Biology - Animal. 22: 749-755. PMID 3465719 DOI: 10.1007/Bf02621092  0.358
1986 Rizzino A, Ruff E. Parameters for optimizing detection of transforming growth factors Journal of Tissue Culture Methods. 10: 109-115. DOI: 10.1007/Bf01404601  0.325
1985 Rizzino A, Bowen-Pope DF. Production of PDGF-like growth factors by embryonal carcinoma cells and binding of PDGF to their endoderm-like differentiated cells Developmental Biology. 110: 15-22. PMID 2989042 DOI: 10.1016/0012-1606(85)90058-2  0.459
1983 Rizzino A. Two multipotent embryonal carcinoma cell lines irreversibly differentiate in defined media Developmental Biology. 95: 126-136. PMID 6681783 DOI: 10.1016/0012-1606(83)90012-X  0.358
1983 Rizzino A, Orme LS, De Larco JE. Embryonal carcinoma cell growth and differentiation. Production of and response to molecules with transforming growth factor activity Experimental Cell Research. 143: 143-152. PMID 6297938 DOI: 10.1016/0014-4827(83)90116-7  0.399
1979 Rizzino A, Sherman MI. Development and differentiation of mouse blastocysts in serum-free medium Experimental Cell Research. 121: 221-233. PMID 87331 DOI: 10.1016/0014-4827(79)90001-6  0.303
Low-probability matches (unlikely to be authored by this person)
1981 Darmon M, Serrero G, Rizzino A, Sato G. Isolation of myoblastic, fibro-adipogenic, and fibroblastic clonal cell lines from a common precursor and study of their requirements for growth and differentiation Experimental Cell Research. 132: 313-327. PMID 7215448 DOI: 10.1016/0014-4827(81)90107-5  0.293
1992 Wilder PJ, Rizzino A. TGF-β does not appear to mediate all effects of 12-O- tetradecanoylphorbol-13-acetate on the anchorage-independent growth of murine epithelial JB6 cells [7] In Vitro Cellular and Developmental Biology - Animal. 28: 581-582. PMID 1429357 DOI: 10.1007/Bf02631027  0.284
1993 Wilder PJ, Rizzino A. Mouse genetics in the 21st century: using gene targeting to create a cornucopia of mouse mutants possessing precise genetic modifications Cytotechnology. 11: 79-99. PMID 7763692 DOI: 10.1007/BF00748997  0.279
2023 Rohrer KA, Song H, Akbar A, Chen Y, Pramanik S, Wilder PJ, McIntyre EM, Chaturvedi NK, Bhakat KK, Rizzino A, Coulter DW, Ray S. STAT3 Inhibition Attenuates MYC Expression by Modulating Co-Activator Recruitment and Suppresses Medulloblastoma Tumor Growth by Augmenting Cisplatin Efficacy In Vivo. Cancers. 15. PMID 37190167 DOI: 10.3390/cancers15082239  0.276
1986 Ruff E, Rizzino A. Preparation and binding of radioactively labeled porcine transforming growth factor type β Biochemical and Biophysical Research Communications. 138: 714-719. PMID 2874805 DOI: 10.1016/S0006-291X(86)80555-1  0.274
1989 Veomett G, Kuszynski C, Kazakoff P, Rizzino A. Cell density regulates the number of cell surface receptors for fibroblast growth factor Biochemical and Biophysical Research Communications. 159: 694-700. PMID 2539122 DOI: 10.1016/0006-291X(89)90050-8  0.27
1993 Rizzino A. Understanding the roles of growth factors in carcinogenesis: Modulation of autocrine growth control by differentiation International Journal of Developmental Biology. 37: 61-65. PMID 8389580  0.267
1990 Kelly D, Campbell WJ, Tiesman J, Rizzino A. Regulation and expression of transforming growth factor type-ß during early mammalian development Cytotechnology. 4: 227-242. PMID 1366990 DOI: 10.1007/BF00563783  0.267
1990 Campbell WJ, Kelly D, Rizzino A. Expression of transforming growth factor-β3 by embryonal carcinoma cells, parietal endoderm-like cells and early mouse embryos In Vitro Cellular &Amp; Developmental Biology. 26: 1181-1185. PMID 1964159 DOI: 10.1007/BF02623696  0.264
1991 Rizzino A, Kazakoff P. Iodination of peptide growth factors: Platelet-derived growth factor and fibroblast growth factor Methods in Enzymology. 198: 467-479. PMID 1649955 DOI: 10.1016/0076-6879(91)98046-9  0.263
2001 Wilder PJ, Desler MM, Nowling TK, Rizzino A. Isolation and characterization of the murine transforming growth factor-β2 promoter Gene. 270: 201-209. PMID 11404017 DOI: 10.1016/S0378-1119(01)00475-9  0.255
1984 Rizzino A, Powen-Pope D. Production of and response to PDGF-like factors by early embryonic cells Federation Proceedings. 43.  0.25
1997 Wilder PJ, Mountjoy C, MacLeod MC, Rizzino A. DNA sequence and nucleosome placement on the murine fibroblast growth factor-4 gene Mitochondrial Dna. 7: 117-121. PMID 9063648 DOI: 10.3109/10425179709020158  0.246
1987 Rizzino A. Appearance of High Affinity Receptors for Type β Transforming Growth Factor during Differentiation of Murine Embryonal Carcinoma Cells Cancer Research. 47: 4386-4390. PMID 2886219  0.244
1980 Rizzino A, Crowley C. Growth and differentiation of embryonal carcinoma cell line F9 in defined media Proceedings of the National Academy of Sciences of the United States of America. 77: 457-461. PMID 6244561 DOI: 10.1073/pnas.77.1.457  0.242
1983 Rizzino A. Model systems for studying the differentiation of embryonal carcinoma cells Cell Biology International Reports. 7: 559-560. DOI: 10.1016/0309-1651(83)90177-7  0.238
1985 Rizzino A. Early mouse embryos produce and release factors with transforming growth factor activity In Vitro Cellular &Amp; Developmental Biology. 21: 531-536. PMID 3862661 DOI: 10.1007/BF02620847  0.229
1988 Rizzino A, Ruff E, Kazakoff P. Isolation and characterization of a-431 cells that retain high epidermal growth factor binding capacity and respond to epidermal growth factor by growth stimulation Cancer Research. 48: 2377-2381. PMID 3258542  0.229
1980 Rizzino A, Terranova V, Rohrbach D, Crowley C, Rizzino H. The effects of laminin on the growth and differentiation of embryonal carcinoma cells in defined media Journal of Supramolecular and Cellular Biochemistry. 13: 243-253. PMID 7242089  0.229
1982 Rizzino A. Embryonal carcinoma cells release factors with transforming growth factor (TGF) activity Journal of Cell Biology. 95.  0.228
1977 Beatriz Levy W, Rizzino A. Distribution of polyadenylated RNA sequences in the cytoplasm of Drosophila cells Experimental Cell Research. 106: 377-380. PMID 405226 DOI: 10.1016/0014-4827(77)90183-5  0.228
2019 Ray S, Coulter D, Wilder P, Sughroue J, Chaturvedi N, Mcguire T, Joshi S, Sharp G, Bhakat K, Rizzino A. Abstract 2892: Genetic inhibition of STAT3 increases medulloblastoma chemosensitivity Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2892  0.22
1982 Rizzino A, Rapp UR, Gonda MA. Dome Formation by a Retrovirus-Induced Lung Adenocarcinoma Cell Line Cancer Research. 42: 1881-1887. PMID 6279287  0.218
1978 Rizzino A, Sato G. Growth of embryonal carcinoma cells in serum-free medium Proceedings of the National Academy of Sciences of the United States of America. 75: 1844-1848. PMID 77018  0.216
1988 Rizzino A. Transforming growth factor-β: Multiple effects on cell differentiation and extracellular matrices Developmental Biology. 130: 411-422. PMID 2904386 DOI: 10.1016/0012-1606(88)90337-5  0.216
1988 Rizzino A, Kazakoff P, Ruff E, Kuszynski C, Nebelsick J. Regulatory effects of cell density on the binding of transforming growth factor β, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor Cancer Research. 48: 4266-4271. PMID 3260536  0.209
1978 Rizzino A, Blumenthal AB. Synchronization of drosophila cells in culture In Vitro. 14: 437-442. PMID 352915 DOI: 10.1007/BF02616105  0.2
1990 Tiesman J, Rizzino A. Nucleotide sequence of the 5′-flanking region of the mouse κ-FGF oncogene exhibits an alternating purine: pyrimidine motif with the potential to form Z-DNA Gene. 96: 311-312. PMID 2269443 DOI: 10.1016/0378-1119(90)90270-2  0.198
1991 Wilder PJ, Rizzino A. Effects of Transforming Growth Factor β on the Anchorage-independent Growth of Murine Epithelial JB6 Cells Cancer Research. 51: 5898-5902. PMID 1933858  0.189
1979 Rizzino A, Rizzino H, Sato G. Defined media and the determination of nutritional and hormonal requirements of mammalian cells in culture Nutrition Reviews. 37: 369-378. PMID 394042  0.186
1981 Brunet N, Rizzino A, Gourdji D, Tixier-Vidal A. Effects of thyroliberin (TRH) on cell proliferation and prolactin secretion by GH3/B6 rat pituitary cells: a comparison between serum-free and serum-supplemented media. Journal of Cellular Physiology. 109: 363-72. PMID 6795214 DOI: 10.1002/jcp.1041090220  0.182
1986 Rizzino A, Ruff E, Rizzino H. Induction and Modulation of Anchorage-independent Growth by Platelet-derived Growth Factor, Fibroblast Growth Factor, and Transforming Growth Factor-β Cancer Research. 46: 2816-2820. PMID 3457628  0.181
1984 Rizzino A. Behavior of transforming growth factors in serum-free media: An improved assay for transforming growth factors In Vitro: Journal of the Tissue Culture Association. 20: 815-822. PMID 6335125 DOI: 10.1007/BF02618298  0.181
1999 Kelly DL, Rizzino A. Growth regulatory factors and carcinogenesis: The roles played by transforming growth factor β, its receptors and signaling pathways Anticancer Research. 19: 4791-4807. PMID 10697593  0.178
1979 Brunet N, Rizzino A, Tixier-Vidal A, Gourdji D. Effects of thyroliberin on cell proliferation and prolactin secretion by GH3/B6 rat pituitary cells grown in serum free medium as compared to serum supplemented medium Cancer Treatment Reports. 63: No. 139.  0.168
1992 Sacco O, Romberger D, Rizzino A, Beckmann JD, Rennard SI, Spurzem JR. Spontaneous production of transforming growth factor-beta 2 by primary cultures of bronchial epithelial cells. Effects on cell behavior in vitro. The Journal of Clinical Investigation. 90: 1379-85. PMID 1401072 DOI: 10.1172/Jci116004  0.162
2000 Xie W, Stribley JA, Chatonnet A, Wilder PJ, Rizzino A, McComb RD, Taylor P, Hinrichs SH, Lockridge O. Postnatal developmental delay and supersensitivity to organophosphate in gene-targeted mice lacking acetylcholinesterase. The Journal of Pharmacology and Experimental Therapeutics. 293: 896-902. PMID 10869390  0.139
1970 Rizzino AA, Barouch WW, Eisenberg E, Moos C. Actin-heavy meromyosin binding. determination of binding stoichiometry from adenosine triphosphatase kinetic measurements Biochemistry. 9: 2402-2408. PMID 5423259  0.124
2021 Ray S, Chaturvedi NK, Bhakat KK, Rizzino A, Mahapatra S. Subgroup-Specific Diagnostic, Prognostic, and Predictive Markers Influencing Pediatric Medulloblastoma Treatment. Diagnostics (Basel, Switzerland). 12. PMID 35054230 DOI: 10.3390/diagnostics12010061  0.121
1979 Bottenstein J, Hayashi I, Hutchings S, Masui H, Mather J, McClure DB, Ohasa S, Rizzino A, Sato G, Serrero G, Wolfe R, Wu R. The growth of cells in serum-free hormone-supplemented media. Methods in Enzymology. 58: 94-109. PMID 423795 DOI: 10.1016/S0076-6879(79)58127-0  0.119
1977 Rizzino A, Mastanduno M, Freundlich M. Partial derepression of the isoleucine-valine enzymes during methionine starvation in Salmonella typhimurium Bba Section Nucleic Acids and Protein Synthesis. 475: 267-275. PMID 321028 DOI: 10.1016/0005-2787(77)90017-X  0.114
1995 Nottet HS, Jett M, Flanagan CR, Zhai QH, Persidsky Y, Rizzino A, Bernton EW, Genis P, Baldwin T, Schwartz J. A regulatory role for astrocytes in HIV-1 encephalitis. An overexpression of eicosanoids, platelet-activating factor, and tumor necrosis factor-alpha by activated HIV-1-infected monocytes is attenuated by primary human astrocytes. Journal of Immunology (Baltimore, Md. : 1950). 154: 3567-81. PMID 7897236  0.111
1987 Rizzino A. [32] Soft agar growth assays for transforming growth factors and mitogenic peptides Methods in Enzymology. 146: 341-352. PMID 3479675 DOI: 10.1016/S0076-6879(87)46035-7  0.09
1975 Bresalier RS, Rizzino AA, Freundlich M. Reduced maximal levels of derepression of the isoleucine-valine and leucine enzymes in his T mutants of Salmonella typhimurium Nature. 253: 279-280. PMID 1089896 DOI: 10.1038/253279a0  0.085
2008 Sherman MI, Shalgi R, Rizzino A, Sellens MH, Gay S, Gay R. Changes in the Surface of the Mouse Blastocyst at Implantation Maternal Recognition of Pregnancy. 33-52. DOI: 10.1002/9780470720479.ch3  0.071
1974 Rizzino AA, Bresalier RS, Freundlich M. Depressed levels of the isoleucine valine and leucine enzymes in hisT1504, a strain of Salmonella typhimurium with altered leucine transfer ribonucleic acid Journal of Bacteriology. 117: 449-455. PMID 4359646  0.058
1975 Rizzino AA, Freundlich M. Estimation of in vivo aminoacylation by periodate oxidation: tRNA alterations and iodate inhibition Analytical Biochemistry. 66: 446-449. PMID 166571 DOI: 10.1016/0003-2697(75)90612-0  0.055
1991 Tiesman J, Rizzino A. A rapid and reliable method for the purification of high-quality plasmid DNA for double-stranded sequencing Biotechniques. 10. PMID 2064770  0.035
1989 Rizzino A. Introduction Cytotechnology. 2: 255-257. DOI: 10.1007/BF00364991  0.02
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