Benoit de Crombrugghe - Publications

Affiliations: 
The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Molecular Biology, Genetics, Biochemistry

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Li IMH, Horwell AL, Chu G, de Crombrugghe B, Bou-Gharios G. Characterization of Mesenchymal-Fibroblast Cells Using the Col1a2 Promoter/Enhancer. Methods in Molecular Biology (Clifton, N.J.). 1627: 139-161. PMID 28836200 DOI: 10.1007/978-1-4939-7113-8_10  0.301
2016 Yasuda H, Oh CD, Chen D, de Crombrugghe B, Kim JH. A Novel Regulatory Mechanism of Type II Collagen Expression via a SOX9-Dependent Enhancer in Intron 6. The Journal of Biological Chemistry. PMID 27881681 DOI: 10.1074/jbc.M116.758425  0.691
2016 Oh CD, Yasuda H, Zhao W, Henry SP, Zhang Z, Xue M, de Crombrugghe B, Chen D. SOX9 directly Regulates CTGF/CCN2 Transcription in Growth Plate Chondrocytes and in Nucleus Pulposus Cells of Intervertebral Disc. Scientific Reports. 6: 29916. PMID 27436052 DOI: 10.1038/srep29916  0.67
2015 Oh CD, Lu Y, Liang S, Mori-Akiyama Y, Chen D, de Crombrugghe B, Yasuda H. Correction: SOX9 Regulates Multiple Genes in Chondrocytes, Including Genes Encoding ECM Proteins, ECM Modification Enzymes, Receptors, and Transporters. Plos One. 10: e0143156. PMID 26562508 DOI: 10.1371/Journal.Pone.0143156  0.782
2015 Chen Q, Sinha K, Deng JM, Yasuda H, Krahe R, Behringer RR, de Crombrugghe B. Mesenchymal Deletion of Histone Demethylase NO66 in Mice Promotes Bone Formation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 25736226 DOI: 10.1002/jbmr.2494  0.627
2014 Oh CD, Lu Y, Liang S, Mori-Akiyama Y, Chen D, de Crombrugghe B, Yasuda H. SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters. Plos One. 9: e107577. PMID 25229425 DOI: 10.1371/Journal.Pone.0107577  0.806
2014 Rashid H, Ma C, Chen H, Wang H, Hassan MQ, Sinha K, de Crombrugghe B, Javed A. Sp7 and Runx2 molecular complex synergistically regulate expression of target genes. Connective Tissue Research. 55: 83-7. PMID 25158187 DOI: 10.3109/03008207.2014.923872  0.352
2013 Hattori T, Kishino T, Stephen S, Eberspaecher H, Maki S, Takigawa M, de Crombrugghe B, Yasuda H. E6-AP/UBE3A protein acts as a ubiquitin ligase toward SOX9 protein. The Journal of Biological Chemistry. 288: 35138-48. PMID 24155239 DOI: 10.1074/jbc.M113.486795  0.602
2013 Chen Q, Liu W, Sinha KM, Yasuda H, de Crombrugghe B. Identification and characterization of microRNAs controlled by the osteoblast-specific transcription factor Osterix. Plos One. 8: e58104. PMID 23472141 DOI: 10.1371/journal.pone.0058104  0.573
2012 Henry SP, Liang S, Akdemir KC, de Crombrugghe B. The postnatal role of Sox9 in cartilage. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 2511-25. PMID 22777888 DOI: 10.1002/Jbmr.1696  0.318
2012 Zhang C, Dai H, de Crombrugghe B. Characterization of Dkk1 gene regulation by the osteoblast-specific transcription factor Osx. Biochemical and Biophysical Research Communications. 420: 782-6. PMID 22459449 DOI: 10.1016/j.bbrc.2012.03.073  0.385
2012 Cao Z, Zhang H, Zhou X, Han X, Ren Y, Gao T, Xiao Y, de Crombrugghe B, Somerman MJ, Feng JQ. Genetic evidence for the vital function of Osterix in cementogenesis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 1080-92. PMID 22246569 DOI: 10.1002/jbmr.1552  0.322
2011 Wang JC, Sonnylal S, Arnett FC, De Crombrugghe B, Zhou X. Attenuation of expression of extracellular matrix genes with siRNAs to Sparc and Ctgf in skin fibroblasts of CTGF transgenic mice. International Journal of Immunopathology and Pharmacology. 24: 595-601. PMID 21978691 DOI: 10.1177/039463201102400305  0.318
2010 Dancer JY, Henry SP, Bondaruk J, Lee S, Ayala AG, de Crombrugghe B, Czerniak B. Expression of master regulatory genes controlling skeletal development in benign cartilage and bone forming tumors. Human Pathology. 41: 1788-93. PMID 21078438 DOI: 10.1016/j.humpath.2010.06.008  0.326
2010 Yang F, Tang W, So S, de Crombrugghe B, Zhang C. Sclerostin is a direct target of osteoblast-specific transcription factor osterix. Biochemical and Biophysical Research Communications. 400: 684-8. PMID 20816666 DOI: 10.1016/j.bbrc.2010.08.128  0.357
2010 Soeda T, Deng JM, de Crombrugghe B, Behringer RR, Nakamura T, Akiyama H. Sox9-expressing precursors are the cellular origin of the cruciate ligament of the knee joint and the limb tendons. Genesis (New York, N.Y. : 2000). 48: 635-44. PMID 20806356 DOI: 10.1002/Dvg.20667  0.495
2010 Coustry F, Oh CD, Hattori T, Maity SN, de Crombrugghe B, Yasuda H. The dimerization domain of SOX9 is required for transcription activation of a chondrocyte-specific chromatin DNA template. Nucleic Acids Research. 38: 6018-28. PMID 20484372 DOI: 10.1093/Nar/Gkq417  0.758
2010 Oh CD, Maity SN, Lu JF, Zhang J, Liang S, Coustry F, de Crombrugghe B, Yasuda H. Identification of SOX9 interaction sites in the genome of chondrocytes. Plos One. 5: e10113. PMID 20404928 DOI: 10.1371/Journal.Pone.0010113  0.746
2010 Sinha KM, Yasuda H, Coombes MM, Dent SY, de Crombrugghe B. Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase. The Embo Journal. 29: 68-79. PMID 19927124 DOI: 10.1038/emboj.2009.332  0.679
2009 Yasuda H, de Crombrugghe B. Joint formation requires muscle formation and contraction. Developmental Cell. 16: 625-6. PMID 19460337 DOI: 10.1016/j.devcel.2009.05.003  0.557
2009 Baek WY, Lee MA, Jung JW, Kim SY, Akiyama H, de Crombrugghe B, Kim JE. Positive regulation of adult bone formation by osteoblast-specific transcription factor osterix. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 1055-65. PMID 19113927 DOI: 10.1359/jbmr.081248  0.426
2008 Kimura H, Kwan KM, Zhang Z, Deng JM, Darnay BG, Behringer RR, Nakamura T, de Crombrugghe B, Akiyama H. Cthrc1 is a positive regulator of osteoblastic bone formation. Plos One. 3: e3174. PMID 18779865 DOI: 10.1371/Journal.Pone.0003174  0.395
2008 Zhang C, Cho K, Huang Y, Lyons JP, Zhou X, Sinha K, McCrea PD, de Crombrugghe B. Inhibition of Wnt signaling by the osteoblast-specific transcription factor Osterix. Proceedings of the National Academy of Sciences of the United States of America. 105: 6936-41. PMID 18458345 DOI: 10.1073/Pnas.0710831105  0.306
2008 Hattori T, Coustry F, Stephens S, Eberspaecher H, Takigawa M, Yasuda H, de Crombrugghe B. Transcriptional regulation of chondrogenesis by coactivator Tip60 via chromatin association with Sox9 and Sox5. Nucleic Acids Research. 36: 3011-24. PMID 18390577 DOI: 10.1093/nar/gkn150  0.687
2007 Mori-Akiyama Y, van den Born M, van Es JH, Hamilton SR, Adams HP, Zhang J, Clevers H, de Crombrugghe B. SOX9 is required for the differentiation of paneth cells in the intestinal epithelium. Gastroenterology. 133: 539-46. PMID 17681175 DOI: 10.1053/J.Gastro.2007.05.020  0.759
2007 Kimura H, Akiyama H, Nakamura T, de Crombrugghe B. Tenascin-W inhibits proliferation and differentiation of preosteoblasts during endochondral bone formation. Biochemical and Biophysical Research Communications. 356: 935-41. PMID 17395156 DOI: 10.1016/J.Bbrc.2007.03.071  0.463
2007 Akiyama H, Stadler HS, Martin JF, Ishii TM, Beachy PA, Nakamura T, de Crombrugghe B. Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice. Matrix Biology : Journal of the International Society For Matrix Biology. 26: 224-33. PMID 17222543 DOI: 10.1016/J.Matbio.2006.12.002  0.522
2007 Gebhard S, Hattori T, Bauer E, Bösl MR, Schlund B, Pöschl E, Adam N, de Crombrugghe B, von der Mark K. BAC constructs in transgenic reporter mouse lines control efficient and specific LacZ expression in hypertrophic chondrocytes under the complete Col10a1 promoter. Histochemistry and Cell Biology. 127: 183-94. PMID 17051351 DOI: 10.1007/s00418-006-0236-8  0.319
2006 Schmidl M, Adam N, Surmann-Schmitt C, Hattori T, Stock M, Dietz U, de Crombrugghe B, Pöschl E, von der Mark K. Twisted gastrulation modulates bone morphogenetic protein-induced collagen II and X expression in chondrocytes in vitro and in vivo. The Journal of Biological Chemistry. 281: 31790-800. PMID 16905550 DOI: 10.1074/jbc.M603419200  0.339
2006 Hattori T, Eberspaecher H, Lu J, Zhang R, Nishida T, Kahyo T, Yasuda H, de Crombrugghe B. Interactions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9. The Journal of Biological Chemistry. 281: 14417-28. PMID 16554309 DOI: 10.1074/jbc.M511330200  0.648
2006 Zhang R, Murakami S, Coustry F, Wang Y, de Crombrugghe B. Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation. Proceedings of the National Academy of Sciences of the United States of America. 103: 365-70. PMID 16387856 DOI: 10.1073/Pnas.0507979103  0.735
2006 Wang X, Kua HY, Hu Y, Guo K, Zeng Q, Wu Q, Ng HH, Karsenty G, de Crombrugghe B, Yeh J, Li B. p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling. The Journal of Cell Biology. 172: 115-25. PMID 16380437 DOI: 10.1083/Jcb.200507106  0.497
2005 Akiyama H, Kim JE, Nakashima K, Balmes G, Iwai N, Deng JM, Zhang Z, Martin JF, Behringer RR, Nakamura T, de Crombrugghe B. Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors. Proceedings of the National Academy of Sciences of the United States of America. 102: 14665-70. PMID 16203988 DOI: 10.1073/Pnas.0504750102  0.534
2005 Akiyama H, Kamitani T, Yang X, Kandyil R, Bridgewater LC, Fellous M, Mori-Akiyama Y, de Crombrugghe B. The transcription factor Sox9 is degraded by the ubiquitin-proteasome system and stabilized by a mutation in a ubiquitin-target site. Matrix Biology : Journal of the International Society For Matrix Biology. 23: 499-505. PMID 15694126 DOI: 10.1016/J.Matbio.2004.10.002  0.804
2004 Gebhard S, Pöschl E, Riemer S, Bauer E, Hattori T, Eberspaecher H, Zhang Z, Lefebvre V, de Crombrugghe B, von der Mark K. A highly conserved enhancer in mammalian type X collagen genes drives high levels of tissue-specific expression in hypertrophic cartilage in vitro and in vivo. Matrix Biology : Journal of the International Society For Matrix Biology. 23: 309-22. PMID 15464363 DOI: 10.1016/j.matbio.2004.05.010  0.644
2004 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B. Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes & Development. 18: 1072-87. PMID 15132997 DOI: 10.1101/Gad.1171104  0.75
2004 Akiyama H, Chaboissier MC, Behringer RR, Rowitch DH, Schedl A, Epstein JA, De Crombrugghe B. Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa Proceedings of the National Academy of Sciences of the United States of America. 101: 6502-6507. PMID 15096597 DOI: 10.1073/Pnas.0401711101  0.708
2004 Murakami S, Balmes G, McKinney S, Zhang Z, Givol D, de Crombrugghe B. Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype. Genes & Development. 18: 290-305. PMID 14871928 DOI: 10.1101/Gad.1179104  0.726
2003 Bhattacharya A, Deng JM, Zhang Z, Behringer R, de Crombrugghe B, Maity SN. The B subunit of the CCAAT box binding transcription factor complex (CBF/NF-Y) is essential for early mouse development and cell proliferation. Cancer Research. 63: 8167-72. PMID 14678971  0.678
2003 Nakashima K, de Crombrugghe B. Transcriptional mechanisms in osteoblast differentiation and bone formation. Trends in Genetics : Tig. 19: 458-66. PMID 12902164 DOI: 10.1016/S0168-9525(03)00176-8  0.358
2003 Mori-Akiyama Y, Akiyama H, Rowitch DH, De Crombrugghe B. Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest Proceedings of the National Academy of Sciences of the United States of America. 100: 9360-9365. PMID 12878728 DOI: 10.1073/Pnas.1631288100  0.782
2003 Kypriotou M, Fossard-Demoor M, Chadjichristos C, Ghayor C, de Crombrugghe B, Pujol JP, Galéra P. SOX9 exerts a bifunctional effect on type II collagen gene (COL2A1) expression in chondrocytes depending on the differentiation state. Dna and Cell Biology. 22: 119-29. PMID 12713737 DOI: 10.1089/104454903321515922  0.394
2003 Denton CP, Zheng B, Evans LA, Shi-wen X, Ong VH, Fisher I, Lazaridis K, Abraham DJ, Black CM, de Crombrugghe B. Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice. The Journal of Biological Chemistry. 278: 25109-19. PMID 12707256 DOI: 10.1074/jbc.M300636200  0.301
2003 Schaefer JF, Millham ML, de Crombrugghe B, Buckbinder L. FGF signaling antagonizes cytokine-mediated repression of Sox9 in SW1353 chondrosarcoma cells. Osteoarthritis and Cartilage. 11: 233-41. PMID 12681949 DOI: 10.1016/s1063-4584(02)00354-0  0.357
2003 Wehrli BM, Huang W, De Crombrugghe B, Ayala AG, Czerniak B. Sox9, a master regulator of chondrogenesis, distinguishes mesenchymal chondrosarcoma from other small blue round cell tumors. Human Pathology. 34: 263-9. PMID 12673561 DOI: 10.1053/hupa.2003.41  0.612
2003 Bridgewater LC, Walker MD, Miller GC, Ellison TA, Holsinger LD, Potter JL, Jackson TL, Chen RK, Winkel VL, Zhang Z, McKinney S, de Crombrugghe B. Adjacent DNA sequences modulate Sox9 transcriptional activation at paired Sox sites in three chondrocyte-specific enhancer elements. Nucleic Acids Research. 31: 1541-53. PMID 12595563 DOI: 10.1093/Nar/Gkg230  0.357
2002 Akiyama H, Chaboissier MC, Martin JF, Schedl A, de Crombrugghe B. The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes & Development. 16: 2813-28. PMID 12414734 DOI: 10.1101/Gad.1017802  0.763
2002 Huang W, Lu N, Eberspaecher H, De Crombrugghe B. A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene. The Journal of Biological Chemistry. 277: 50668-75. PMID 12381733 DOI: 10.1074/jbc.M206544200  0.678
2002 Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 108: 17-29. PMID 11792318 DOI: 10.1016/S0092-8674(01)00622-5  0.316
2001 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B, Lefebvre V. The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Developmental Cell. 1: 277-90. PMID 11702786 DOI: 10.1016/S1534-5807(01)00003-X  0.59
2001 de Crombrugghe B, Lefebvre V, Nakashima K. Regulatory mechanisms in the pathways of cartilage and bone formation. Current Opinion in Cell Biology. 13: 721-7. PMID 11698188 DOI: 10.1016/s0955-0674(00)00276-3  0.557
2001 Lefebvre V, Behringer RR, de Crombrugghe B. L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway. Osteoarthritis and Cartilage. 9: S69-75. PMID 11680692 DOI: 10.1053/Joca.2001.0447  0.556
2001 Coustry F, Hu Q, de Crombrugghe B, Maity SN. CBF/NF-Y functions both in nucleosomal disruption and transcription activation of the chromatin-assembled topoisomerase IIalpha promoter. Transcription activation by CBF/NF-Y in chromatin is dependent on the promoter structure. The Journal of Biological Chemistry. 276: 40621-30. PMID 11514576 DOI: 10.1074/Jbc.M106918200  0.668
2001 Bi W, Huang W, Whitworth DJ, Deng JM, Zhang Z, Behringer RR, de Crombrugghe B. Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization. Proceedings of the National Academy of Sciences of the United States of America. 98: 6698-703. PMID 11371614 DOI: 10.1073/Pnas.111092198  0.72
2001 Antoniv TT, De Val S, Wells D, Denton CP, Rabe C, de Crombrugghe B, Ramirez F, Bou-Gharios G. Characterization of an evolutionarily conserved far-upstream enhancer in the human alpha 2(I) collagen (COL1A2) gene. The Journal of Biological Chemistry. 276: 21754-64. PMID 11279244 DOI: 10.1074/Jbc.M101397200  0.336
2001 Huang W, Wang SL, Lozano G, de Crombrugghe B. cDNA library screening using the SOS recruitment system. Biotechniques. 30: 94-8, 100. PMID 11196326 DOI: 10.2144/01301St06  0.563
2001 Huang W, Chung UI, Kronenberg HM, de Crombrugghe B. The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones. Proceedings of the National Academy of Sciences of the United States of America. 98: 160-5. PMID 11120880 DOI: 10.1073/pnas.011393998  0.657
2000 de Crombrugghe B, Lefebvre V, Behringer RR, Bi W, Murakami S, Huang W. Transcriptional mechanisms of chondrocyte differentiation. Matrix Biology : Journal of the International Society For Matrix Biology. 19: 389-94. PMID 10980415 DOI: 10.1016/S0945-053X(00)00094-9  0.822
2000 Huang W, Zhou X, Lefebvre V, de Crombrugghe B. Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer. Molecular and Cellular Biology. 20: 4149-58. PMID 10805756 DOI: 10.1128/Mcb.20.11.4149-4158.2000  0.717
2000 Murakami S, Kan M, McKeehan WL, de Crombrugghe B. Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway. Proceedings of the National Academy of Sciences of the United States of America. 97: 1113-8. PMID 10655493 DOI: 10.1073/Pnas.97.3.1113  0.739
2000 Murakami S, Lefebvre V, de Crombrugghe B. Potent inhibition of the master chondrogenic factor Sox9 gene by interleukin-1 and tumor necrosis factor-alpha. The Journal of Biological Chemistry. 275: 3687-92. PMID 10652367 DOI: 10.1074/Jbc.275.5.3687  0.763
1999 Bi W, Deng JM, Zhang Z, Behringer RR, de Crombrugghe B. Sox9 is required for cartilage formation. Nature Genetics. 22: 85-9. PMID 10319868 DOI: 10.1038/8792  0.655
1999 Faniello MC, Bevilacqua MA, Condorelli G, de Crombrugghe B, Maity SN, Avvedimento VE, Cimino F, Costanzo F. The B subunit of the CAAT-binding factor NFY binds the central segment of the Co-activator p300. The Journal of Biological Chemistry. 274: 7623-6. PMID 10075648 DOI: 10.1074/Jbc.274.12.7623  0.631
1998 Lefebvre V, Li P, de Crombrugghe B. A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. The Embo Journal. 17: 5718-33. PMID 9755172 DOI: 10.1093/Emboj/17.19.5718  0.611
1998 Bridgewater LC, Lefebvre V, De Crombrugghe B. Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer Journal of Biological Chemistry. 273: 14998-15006. PMID 9614107 DOI: 10.1074/jbc.273.24.14998  0.631
1998 Zhou G, Lefebvre V, Zhang Z, Eberspaecher H, de Crombrugghe B. Three high mobility group-like sequences within a 48-base pair enhancer of the Col2a1 gene are required for cartilage-specific expression in vivo. The Journal of Biological Chemistry. 273: 14989-97. PMID 9614106 DOI: 10.1074/jbc.273.24.14989  0.641
1998 Maity SN, de Crombrugghe B. Role of the CCAAT-binding protein CBF/NF-Y in transcription. Trends in Biochemical Sciences. 23: 174-8. PMID 9612081 DOI: 10.1016/S0968-0004(98)01201-8  0.646
1998 Lefebvre V, de Crombrugghe B. Toward understanding SOX9 function in chondrocyte differentiation. Matrix Biology : Journal of the International Society For Matrix Biology. 16: 529-40. PMID 9569122 DOI: 10.1016/s0945-053x(98)90065-8  0.407
1997 Bi W, Wu L, Coustry F, de Crombrugghe B, Maity SN. DNA binding specificity of the CCAAT-binding factor CBF/NF-Y. The Journal of Biological Chemistry. 272: 26562-72. PMID 9334236 DOI: 10.1074/Jbc.272.42.26562  0.725
1997 Zhao Q, Eberspaecher H, Lefebvre V, De Crombrugghe B. Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 209: 377-86. PMID 9264261 DOI: 10.1002/(Sici)1097-0177(199708)209:4<377::Aid-Aja5>3.0.Co;2-F  0.559
1997 Chen SS, Ruteshouser EC, Maity SN, de Crombrugghe B. Cell-specific in vivo DNA-protein interactions at the proximal promoters of the pro alpha 1(I) and the pro alpha2(I) collagen genes. Nucleic Acids Research. 25: 3261-8. PMID 9241239 DOI: 10.1093/Nar/25.16.3261  0.678
1997 Lefebvre V, Huang W, Harley VR, Goodfellow PN, de Crombrugghe B. SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Molecular and Cellular Biology. 17: 2336-46. PMID 9121483 DOI: 10.1128/Mcb.17.4.2336  0.773
1997 Hasegawa T, Takeuchi A, Miyaishi O, Isobe Ki, de Crombrugghe B. Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes. The Journal of Biological Chemistry. 272: 4915-23. PMID 9030551 DOI: 10.1074/jbc.272.8.4915  0.387
1996 Garrett-Sinha LA, Eberspaecher H, Seldin MF, de Crombrugghe B. A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells. The Journal of Biological Chemistry. 271: 31384-90. PMID 8940147 DOI: 10.1074/Jbc.271.49.31384  0.733
1996 Sinha S, Maity SN, Seldin MF, de Crombrugghe B. Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor. Genomics. 37: 260-3. PMID 8921405 DOI: 10.1006/Geno.1996.0555  0.603
1996 Maity SN, De Crombrugghe B. Purification, characterization, and role of CCAAT-binding factor in transcription. Methods in Enzymology. 273: 217-32. PMID 8791615 DOI: 10.1016/S0076-6879(96)73022-7  0.655
1996 Hasegawa T, Zhou X, Garrett LA, Ruteshouser EC, Maity SN, de Crombrugghe B. Evidence for three major transcription activation elements in the proximal mouse proalpha2(I) collagen promoter. Nucleic Acids Research. 24: 3253-60. PMID 8774909  0.682
1996 Lefebvre V, Zhou G, Mukhopadhyay K, Smith CN, Zhang Z, Eberspaecher H, Zhou X, Sinha S, Maity SN, de Crombrugghe B. An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes. Molecular and Cellular Biology. 16: 4512-23. PMID 8754852  0.761
1996 Kim IS, Sinha S, de Crombrugghe B, Maity SN. Determination of functional domains in the C subunit of the CCAAT-binding factor (CBF) necessary for formation of a CBF-DNA complex: CBF-B interacts simultaneously with both the CBF-A and CBF-C subunits to form a heterotrimeric CBF molecule. Molecular and Cellular Biology. 16: 4003-13. PMID 8754798 DOI: 10.1128/Mcb.16.8.4003  0.596
1996 Lefebvre V, Mukhopadhyay K, Zhou G, Garofalo S, Smith C, Eberspaecher H, Kimura JH, de Crombrugghe B. A 47-bp sequence of the first intron of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte Expression. Annals of the New York Academy of Sciences. 785: 284-7. PMID 8702156 DOI: 10.1111/J.1749-6632.1996.Tb56285.X  0.547
1996 Coustry F, Maity SN, Sinha S, de Crombrugghe B. The transcriptional activity of the CCAAT-binding factor CBF is mediated by two distinct activation domains, one in the CBF-B subunit and the other in the CBF-C subunit. The Journal of Biological Chemistry. 271: 14485-91. PMID 8662945 DOI: 10.1074/Jbc.271.24.14485  0.65
1996 Rossert JA, Chen SS, Eberspaecher H, Smith CN, de Crombrugghe B. Identification of a minimal sequence of the mouse pro-alpha 1(I) collagen promoter that confers high-level osteoblast expression in transgenic mice and that binds a protein selectively present in osteoblasts. Proceedings of the National Academy of Sciences of the United States of America. 93: 1027-31. PMID 8577708  0.357
1996 Sinha S, Kim IS, Sohn KY, de Crombrugghe B, Maity SN. Three classes of mutations in the A subunit of the CCAAT-binding factor CBF delineate functional domains involved in the three-step assembly of the CBF-DNA complex. Molecular and Cellular Biology. 16: 328-37. PMID 8524312 DOI: 10.1128/Mcb.16.1.328  0.7
1995 Ala-Kokko L, Kvist AP, Metsäranta M, Kivirikko KI, de Crombrugghe B, Prockop DJ, Vuorio E. Conservation of the sizes of 53 introns and over 100 intronic sequences for the binding of common transcription factors in the human and mouse genes for type II procollagen (COL2A1). The Biochemical Journal. 308: 923-9. PMID 8948452 DOI: 10.1042/Bj3080923  0.304
1995 Zhou G, Garofalo S, Mukhopadhyay K, Lefebvre V, Smith CN, Eberspaecher H, de Crombrugghe B. A 182 bp fragment of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice. Journal of Cell Science. 108: 3677-84. PMID 8719874  0.33
1995 Sinha S, Maity SN, Lu J, de Crombrugghe B. Recombinant rat CBF-C, the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3. Proceedings of the National Academy of Sciences of the United States of America. 92: 1624-8. PMID 7878029 DOI: 10.1073/Pnas.92.5.1624  0.604
1995 Lefebvre V, Garofalo S, de Crombrugghe B. Type X collagen gene expression in mouse chondrocytes immortalized by a temperature-sensitive simian virus 40 large tumor antigen. The Journal of Cell Biology. 128: 239-45. PMID 7822418 DOI: 10.1083/Jcb.128.1.239  0.575
1995 Coustry F, Maity SN, de Crombrugghe B. Studies on transcription activation by the multimeric CCAAT-binding factor CBF. The Journal of Biological Chemistry. 270: 468-75. PMID 7814413 DOI: 10.1074/Jbc.270.1.468  0.667
1995 Rossert J, Eberspaecher H, de Crombrugghe B. Separate cis-acting DNA elements of the mouse pro-alpha 1(I) collagen promoter direct expression of reporter genes to different type I collagen-producing cells in transgenic mice. The Journal of Cell Biology. 129: 1421-32. PMID 7775585 DOI: 10.1083/jcb.129.5.1421  0.348
1995 Mukhopadhyay K, Lefebvre V, Zhou G, Garofalo S, Kimura JH, de Crombrugghe B. Use of a new rat chondrosarcoma cell line to delineate a 119-base pair chondrocyte-specific enhancer element and to define active promoter segments in the mouse pro-alpha 1(II) collagen gene. The Journal of Biological Chemistry. 270: 27711-9. PMID 7499238 DOI: 10.1074/Jbc.270.46.27711  0.619
1994 Lefebvre V, Garofalo S, Zhou G, Metsäranta M, Vuorio E, De Crombrugghe B. Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice. Matrix Biology : Journal of the International Society For Matrix Biology. 14: 329-35. PMID 7827756 DOI: 10.1016/0945-053X(94)90199-6  0.556
1994 Sohn KY, Maity SN, de Crombrugghe B. Studies on the structure of the mouse CBF-A gene and properties of a truncated CBF-A isoform generated from an alternatively spliced RNA. Gene. 139: 147-53. PMID 7509302 DOI: 10.1016/0378-1119(94)90748-X  0.658
1993 Zhao GQ, Zhao Q, Zhou X, Mattei MG, de Crombrugghe B. TFEC, a basic helix-loop-helix protein, forms heterodimers with TFE3 and inhibits TFE3-dependent transcription activation. Molecular and Cellular Biology. 13: 4505-12. PMID 8336698  0.318
1993 D'Souza RN, Niederreither K, de Crombrugghe B. Osteoblast-specific expression of the alpha 2(I) collagen promoter in transgenic mice: correlation with the distribution of TGF-beta 1. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 8: 1127-36. PMID 8237483 DOI: 10.1002/Jbmr.5650080914  0.351
1992 Niederreither K, D'Souza RN, de Crombrugghe B. Minimal DNA sequences that control the cell lineage-specific expression of the pro alpha 2(I) collagen promoter in transgenic mice. The Journal of Cell Biology. 119: 1361-70. PMID 1447306 DOI: 10.1083/Jcb.119.5.1361  0.303
1991 Yang BS, Geddes TJ, Pogulis RJ, de Crombrugghe B, Freytag SO. Transcriptional suppression of cellular gene expression by c-Myc. Molecular and Cellular Biology. 11: 2291-5. PMID 2005911 DOI: 10.1128/MCB.11.4.2291  0.325
1990 Maity SN, Vuorio T, de Crombrugghe B. The B subunit of a rat heteromeric CCAAT-binding transcription factor shows a striking sequence identity with the yeast Hap2 transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 87: 5378-82. PMID 2196566 DOI: 10.1073/Pnas.87.14.5378  0.642
1988 Rossi P, de Crombrugghe B. Formation of a type I collagen RNA dimer by intermolecular base-pairing of a conserved sequence around the translation initiation site. Nucleic Acids Research. 15: 8935-56. PMID 3684576 DOI: 10.1093/Nar/15.21.8935  0.639
1988 Maity SN, Golumbek PT, Karsenty G, de Crombrugghe B. Selective activation of transcription by a novel CCAAT binding factor. Science (New York, N.Y.). 241: 582-5. PMID 3399893 DOI: 10.1126/Science.3399893  0.721
1987 Schmidt A, Rossi P, de Crombrugghe B. Transcriptional control of the mouse alpha 2(I) collagen gene: functional deletion analysis of the promoter and evidence for cell-specific expression. Molecular and Cellular Biology. 6: 347-54. PMID 3785151 DOI: 10.1128/Mcb.6.2.347  0.687
1987 Rossi P, de Crombrugghe B. Identification of a cell-specific transcriptional enhancer in the first intron of the mouse alpha 2 (type I) collagen gene. Proceedings of the National Academy of Sciences of the United States of America. 84: 5590-4. PMID 3039494 DOI: 10.1073/Pnas.84.16.5590  0.673
1986 Setoyama C, Frunzio R, Liau G, Mudryj M, de Crombrugghe B. Transcriptional activation encoded by the v-fos gene. Proceedings of the National Academy of Sciences of the United States of America. 83: 3213-7. PMID 3010284 DOI: 10.1073/Pnas.83.10.3213  0.322
1985 Schmidt A, Setoyama C, de Crombrugghe B. Regulation of a collagen gene promoter by the product of viral mos oncogene. Nature. 314: 286-9. PMID 2984572 DOI: 10.1038/314286a0  0.337
1984 de Crombrugghe B, Busby S, Buc H. Cyclic AMP receptor protein: role in transcription activation. Science (New York, N.Y.). 224: 831-8. PMID 6372090 DOI: 10.1126/science.6372090  0.325
1984 McKeon C, Pastan I, de Crombrugghe B. DNase I sensitivity of the alpha 2(I) collagen gene: correlation with its expression but not with its methylation pattern. Nucleic Acids Research. 12: 3491-502. PMID 6328424 DOI: 10.1093/nar/12.8.3491  0.439
1983 Hirano H, Yamada Y, Sullivan M, de Crombrugghe B, Pastan I, Yamada KM. Isolation of genomic DNA clones spanning the entire fibronectin gene. Proceedings of the National Academy of Sciences of the United States of America. 80: 46-50. PMID 6572007 DOI: 10.1073/pnas.80.1.46  0.544
1983 Merlino GT, McKeon C, de Crombrugghe B, Pastan I. Regulation of the expression of genes encoding types I, II, and III collagen during chick embryonic development. The Journal of Biological Chemistry. 258: 10041-8. PMID 6193105  0.423
1982 Tyagi JS, Merlino GT, de Crombrugghe B, Pastan I. Chicken embryo extracts contain a factor that preferentially blocks the accumulation of RNA polymerase II transcripts in a cell-free system. The Journal of Biological Chemistry. 257: 13001-8. PMID 7130191  0.445
1982 Vogeli G, Ohkubo H, Sobel ME, Yamada Y, Pastan I, de Crombrugghe B. Structure of the promoter for chicken α2 type I collagen gene Proceedings of the National Academy of Sciences of the United States of America. 78: 5334-5338. PMID 6946474 DOI: 10.1073/pnas.78.9.5334  0.406
1982 Busby S, Aiba H, de Crombrugghe B. Mutations in the Escherichia coli operon that define two promoters and the binding site of the cyclic AMP receptor protein. Journal of Molecular Biology. 154: 211-27. PMID 6804633 DOI: 10.1016/0022-2836(82)90061-4  0.719
1982 Pastan IH, Willingham M, de Crombrugghe B, Gottesman MM. Aging and cancer: cyclic 3', 5'-adenosine monophosphate and altered gene activity. National Cancer Institute Monograph. 60: 7-15. PMID 6289108  0.318
1982 Merlino GT, Tyagi JS, de Crombrugghe B, Pastan I. Transcription of the chicken alpha 2 (Type I) collagen gene by homologous cell-free extracts. The Journal of Biological Chemistry. 257: 7254-61. PMID 6282836  0.455
1981 Vogeli G, Ohkubo H, Avvedimento VE, Sullivan M, Yamada Y, Mudryj M, Pastan I, de Crombrugghe B. A repetitive structure in the chick alpha 2-collagen gene. Cold Spring Harbor Symposia On Quantitative Biology. 45: 777-83. PMID 6942950 DOI: 10.1101/Sqb.1981.045.01.096  0.338
1981 Merlino GT, Vogeli G, Yamamoto T, de Crombrugghe B, Pastan I. Accurate in vitro transcriptional initiation of the chick alpha 2 (Type I) collagen gene. The Journal of Biological Chemistry. 256: 11251-8. PMID 6270147  0.477
1981 Dickson LA, Ninomiya Y, Bernard MP, Pesciotta DM, Parsons J, Green G, Eikenberry EF, de Crombrugghe B, Vogeli G, Pastan I, Fietzek PP, Olsen BR. The exon/intron structure of the 3'-region of the pro alpha 2(I) collagen gene. The Journal of Biological Chemistry. 256: 8407-15. PMID 6267043  0.359
1981 Sobel ME, Yamamoto T, De Crombrugghe B, Pastan I. Regulation of procollagen messenger ribonucleic acid levels in Rous sarcoma virus transformed chick embryo fibroblasts Biochemistry. 20: 2678-2684. PMID 6263317 DOI: 10.1021/Bi00512A049  0.362
1981 Fagan JB, Sobel ME, Yamada KM, de Crombrugghe B, Pastan I. Effects of transformation on fibronectin gene expression using cloned fibronectin cDNA Journal of Biological Chemistry. 256: 520-525. PMID 6256355  0.389
1980 Yamada Y, Avvedimento VE, Mudryj M, Ohkubo H, Vogeli G, Irani M, Pastan I, de Crombrugghe B. The collagen gene: evidence for its evolutinary assembly by amplification of a DNA segment containing an exon of 54 bp. Cell. 22: 887-92. PMID 7460017 DOI: 10.1016/0092-8674(80)90565-6  0.4
1980 Vogeli G, Avvedimento EV, Sullivan M, Maizel JV, Lozano G, Adams SL, Pastan I, de Crombrugghe B. Isolation and characterization of genomic DNA coding for α2 type I collagen Nucleic Acids Research. 8: 1823-1837. PMID 7433131 DOI: 10.1093/Nar/8.8.1823  0.367
1980 Ohkubo H, Vogeli G, Mudryj M, Avvedimento VE, Sullivan M, Pastan I, de Crombrugghe B. Isolation and characterization of overlapping genomic clones covering the chicken alpha 2 (type I) collagen gene. Proceedings of the National Academy of Sciences of the United States of America. 77: 7059-63. PMID 6452631 DOI: 10.1073/Pnas.77.12.7059  0.375
1980 Yamamoto T, de Crombrugghe B, Pastan I. Identification of a functional promoter in the long terminal repeat of Rous sarcoma virus. Cell. 22: 787-97. PMID 6257399 DOI: 10.1016/0092-8674(80)90555-3  0.43
1980 Yamamoto T, Sobel ME, Adams SL, Avvedimento VE, DiLauro R, Pastan I, de Crombrugghe B, Showalter A, Pesciotta D, Fietzek P, Olsen B. Construction of a recombinant bacterial plasmid containing pro-α1(I) collagen DNA sequences Journal of Biological Chemistry. 255: 2612-2615. PMID 6244285  0.334
1980 Avvedimento VE, Vogeli G, Yamada Y, Maizel JV, Pastan I, de Crombrugghe B. Correlation between splicing sites within an intron and their sequence complementarity with U1 RNA. Cell. 21: 689-96. PMID 6159982 DOI: 10.1016/0092-8674(80)90432-8  0.369
1980 Taniguchi T, O'Neill M, de Crombrugghe B. Interaction site of Escherichia coli cyclic AMP receptor protein on DNA of galactose operon promoters. Proceedings of the National Academy of Sciences of the United States of America. 76: 5090-4. PMID 228278 DOI: 10.1073/pnas.76.10.5090  0.321
1979 Fagan JB, Yamada KM, de Crombrugghe B, Pastan I. Partial purification and characterization of the messenger RNA for cell fibronectin. Nucleic Acids Research. 6: 3471-80. PMID 573888 DOI: 10.1093/nar/6.11.3471  0.483
1978 Sobel ME, Yamamoto T, Adams SL, DiLauro R, Avvedimento VE, de Crombrugghe B, Pastan I. Construction of a recombinant bacterial plasmid containing a chick pro-α2 collagen gene sequence Proceedings of the National Academy of Sciences of the United States of America. 75: 5846-5850. PMID 366605 DOI: 10.1073/Pnas.75.12.5846  0.391
1978 Howard BH, Adams SL, Sobel ME, Pastan I, de Crombrugghe B. Decreased levels of collagen mRNA in Rous sarcoma virus-transformed chick embryo fibroblasts Journal of Biological Chemistry. 253: 5869-5874. PMID 78927  0.38
1977 Adams SL, Sobel ME, Howard BH, Olden K, Yamada KM, de Crombrugghe B, Pastan I. Levels of translatable mRNAs for cell surface protein, collagen precursors, and two membrane proteins are altered in Rous sarcoma virus transformed chick embryo fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 74: 3399-3403. PMID 198783 DOI: 10.1073/pnas.74.8.3399  0.536
1974 Adhya S, Gottesman M, De Crombrugghe B. Termination and antitermination in transcription: control of gene expression. Basic Life Sciences. 3: 213-21. PMID 4362806 DOI: 10.1007/978-1-4613-4529-9_17  0.344
1973 De Crombrugghe B, Pastan I. Regulation of gene expression by cyclic AMP in Escherichia coli. Symposia of the Society For Experimental Biology. 27: 365-9. PMID 4358368  0.425
1973 De Crombrugghe B, Pastan I, Shaw WV, Rosner JL. Stimulation by cyclic AMP and ppGpp of chloramphenicol acetyl transferase synthesis. Nature: New Biology. 241: 237-9. PMID 4349357 DOI: 10.1038/newbio241237a0  0.35
1973 De Crombrugghe B, Adhya S, Gottesman M, Pastan I. Effect of Rho on transcription of bacterial operons. Nature: New Biology. 241: 260-4. PMID 4348358 DOI: 10.1038/Newbio241260A0  0.415
1971 Chen B, de Crombrugghe B, Anderson WB, Gottesman ME, Pastan I, Perlman RL. On the mechanism of action of lac repressor. Nature: New Biology. 233: 67-70. PMID 4330295 DOI: 10.1038/newbio233067a0  0.611
1971 De Crombrugghe B, Chen B, Anderson W, Nissley P, Gottesman M, Pastan I, Perlman R. Lac DNA, RNA polymerase and cyclic AMP receptor protein, cyclic AMP, lac repressor and inducer are the essential elements for controlled lac transcription. Nature: New Biology. 231: 139-42. PMID 4326354 DOI: 10.1038/newbio231139a0  0.653
1971 De Crombrugghe B, Chen B, Gottesman M, Pastan I, Varmus HE, Emmer M, Perlman RL. Regulation of lac mRNA synthesis in a soluble cell-free system. Nature: New Biology. 230: 37-40. PMID 4324112 DOI: 10.1038/Newbio230037A0  0.649
1970 de Crombrugghe B, Varmus HE, Perlman RL, Pastan IH. Stimulation of lac mRNA synthesis by cyclic AMP in cell free extracts of Escherichia coli. Biochemical and Biophysical Research Communications. 38: 894-901. PMID 4314384 DOI: 10.1016/0006-291X(70)90805-3  0.579
1969 De Crombrugghe B, Perlman RL, Varmus HE, Pastan I. Regulation of inducible enzyme synthesis in Escherichia coli by cyclic adenosine 3', 5'-monophosphate. The Journal of Biological Chemistry. 244: 5828-35. PMID 4310825  0.556
1969 Perlman RL, De Crombrugghe B, Pastan I. Cyclic AMP regulates catabolite and transient repression in E. coli Nature. 223: 810-812. PMID 4307969 DOI: 10.1038/223810a0  0.577
1967 de Crombrugghe B, Edelhoch H. The properties of thyroglobulin. XIV. The structure of reoxidized thyroglobulin. Biochemistry. 5: 2238-45. PMID 4959961 DOI: 10.1021/Bi00871A012  0.444
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