Ganesh K. Kumar - Publications

Affiliations: 
Case Western Reserve University School of Medicine, Cleveland, OH, United States 
Area:
Biochemistry

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Peng YJ, Makarenko VV, Gridina A, Chupikova I, Zhang X, Kumar GK, Fox AP, Prabhakar NR. HS mediates carotid body response to hypoxia but not anoxia. Respiratory Physiology & Neurobiology. PMID 30086385 DOI: 10.1016/j.resp.2018.08.001  0.6
2017 Peng YJ, Zhang X, Gridina A, Chupikova I, McCormick DL, Thomas RJ, Scammell TE, Kim G, Vasavda C, Nanduri J, Kumar GK, Semenza GL, Snyder SH, Prabhakar NR. Complementary roles of gasotransmitters CO and H2S in sleep apnea. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115703 DOI: 10.1073/pnas.1620717114  0.6
2016 Yuan G, Peng YJ, Khan SA, Nanduri J, Singh A, Vasavda C, Semenza GL, Kumar GK, Snyder SH, Prabhakar NR. H2S production by reactive oxygen species in the carotid body triggers hypertension in a rodent model of sleep apnea. Science Signaling. 9: ra80. PMID 27531649 DOI: 10.1126/scisignal.aaf3204  0.6
2016 Nanduri J, Peng YJ, Wang N, Khan SA, Semenza GL, Kumar GK, Prabhakar NR. Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long-term intermittent hypoxia. The Journal of Physiology. PMID 27506145 DOI: 10.1113/JP272346  0.6
2016 Kumar GK. Adapt or avoid. Elife. 5. PMID 26902719 DOI: 10.7554/eLife.14345  0.6
2015 Makarenko VV, Ahmmed GU, Peng YJ, Khan SA, Nanduri J, Kumar GK, Fox AP, Prabhakar NR. CaV3.2 T-type Ca2+ channels mediate the augmented calcium influx in carotid body glomus cells by chronic intermittent hypoxia. Journal of Neurophysiology. jn.00775.2015. PMID 26561606 DOI: 10.1152/jn.00775.2015  0.6
2015 Kumar GK, Peng YJ, Nanduri J, Prabhakar NR. Carotid Body Chemoreflex Mediates Intermittent Hypoxia-Induced Oxidative Stress in the Adrenal Medulla. Advances in Experimental Medicine and Biology. 860: 195-9. PMID 26303481 DOI: 10.1007/978-3-319-18440-1_21  0.6
2015 Yuan G, Vasavda C, Peng YJ, Makarenko VV, Raghuraman G, Nanduri J, Gadalla MM, Semenza GL, Kumar GK, Snyder SH, Prabhakar NR. Protein kinase G-regulated production of H2S governs oxygen sensing. Science Signaling. 8: ra37. PMID 25900831 DOI: 10.1126/scisignal.2005846  0.6
2015 Prabhakar NR, Peng YJ, Kumar GK, Nanduri J. Peripheral chemoreception and arterial pressure responses to intermittent hypoxia. Comprehensive Physiology. 5: 561-77. PMID 25880505 DOI: 10.1002/cphy.c140039  0.6
2015 Nanduri J, Peng YJ, Yuan G, Kumar GK, Prabhakar NR. Hypoxia-inducible factors and hypertension: lessons from sleep apnea syndrome. Journal of Molecular Medicine (Berlin, Germany). 93: 473-80. PMID 25772710 DOI: 10.1007/s00109-015-1274-2  0.6
2015 Kumar GK, Nanduri J, Peng YJ, Prabhakar NR. Neuromolecular mechanisms mediating the effects of chronic intermittent hypoxia on adrenal medulla. Respiratory Physiology & Neurobiology. 209: 115-9. PMID 25583660 DOI: 10.1016/j.resp.2015.01.001  0.6
2015 Makarenko VV, Peng YJ, Yuan G, Fox AP, Kumar GK, Nanduri J, Prabhakar NR. CaV3.2 T-type Ca²⁺ channels in Hâ‚‚S-mediated hypoxic response of the carotid body. American Journal of Physiology. Cell Physiology. 308: C146-54. PMID 25377087 DOI: 10.1152/ajpcell.00141.2014  0.6
2014 Peng YJ, Yuan G, Khan S, Nanduri J, Makarenko VV, Reddy VD, Vasavda C, Kumar GK, Semenza GL, Prabhakar NR. Regulation of hypoxia-inducible factor-α isoforms and redox state by carotid body neural activity in rats. The Journal of Physiology. 592: 3841-58. PMID 24973414 DOI: 10.1113/jphysiol.2014.273789  0.6
2014 Makarenko VV, Usatyuk PV, Yuan G, Lee MM, Nanduri J, Natarajan V, Kumar GK, Prabhakar NR. Intermittent hypoxia-induced endothelial barrier dysfunction requires ROS-dependent MAP kinase activation. American Journal of Physiology. Cell Physiology. 306: C745-52. PMID 24477234 DOI: 10.1152/ajpcell.00313.2013  0.6
2014 Peng YJ, Makarenko VV, Nanduri J, Vasavda C, Raghuraman G, Yuan G, Gadalla MM, Kumar GK, Snyder SH, Prabhakar NR. Inherent variations in CO-H2S-mediated carotid body O2 sensing mediate hypertension and pulmonary edema. Proceedings of the National Academy of Sciences of the United States of America. 111: 1174-9. PMID 24395806 DOI: 10.1073/pnas.1322172111  0.6
2014 Takano N, Peng YJ, Kumar GK, Luo W, Hu H, Shimoda LA, Suematsu M, Prabhakar NR, Semenza GL. Hypoxia-inducible factors regulate human and rat cystathionine β-synthase gene expression. The Biochemical Journal. 458: 203-11. PMID 24328859 DOI: 10.1042/BJ20131350  0.6
2013 Peng YJ, Nanduri J, Raghuraman G, Wang N, Kumar GK, Prabhakar NR. Role of oxidative stress-induced endothelin-converting enzyme activity in the alteration of carotid body function by chronic intermittent hypoxia. Experimental Physiology. 98: 1620-30. PMID 23913764 DOI: 10.1113/expphysiol.2013.073700  0.6
2013 Ramirez JM, Garcia AJ, Anderson TM, Koschnitzky JE, Peng YJ, Kumar GK, Prabhakar NR. Central and peripheral factors contributing to obstructive sleep apneas. Respiratory Physiology & Neurobiology. 189: 344-53. PMID 23770311 DOI: 10.1016/j.resp.2013.06.004  0.6
2013 Yuan G, Peng YJ, Reddy VD, Makarenko VV, Nanduri J, Khan SA, Garcia JA, Kumar GK, Semenza GL, Prabhakar NR. Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 110: E1788-96. PMID 23610397 DOI: 10.1073/pnas.1305961110  0.6
2013 Kumar GK, Raghuraman G, Prabhakar NR. Reactive Oxygen Species and Neuropeptide Y Signaling in Altered Catecholamine Synthesis during Intermittent Hypoxia Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 220-221. DOI: 10.1016/B978-0-12-800044-1.00196-3  0.6
2013 Kumar GK, Prabhakar NR. Neurotransmitter synthesis during intermittent hypoxia: Role of reactive oxygen species-dependent post-translational protein modifications Intermittent Hypoxia: From Molecular Mechanisms to Clinical Applications. 346-353.  0.6
2012 Raghuraman G, Prabhakar NR, Kumar GK. Differential regulation of tyrosine hydroxylase by continuous and intermittent hypoxia. Advances in Experimental Medicine and Biology. 758: 381-5. PMID 23080186 DOI: 10.1007/978-94-007-4584-1_51  0.6
2012 Makarenko VV, Nanduri J, Raghuraman G, Fox AP, Gadalla MM, Kumar GK, Snyder SH, Prabhakar NR. Endogenous H2S is required for hypoxic sensing by carotid body glomus cells. American Journal of Physiology. Cell Physiology. 303: C916-23. PMID 22744006 DOI: 10.1152/ajpcell.00100.2012  0.6
2012 Prabhakar NR, Kumar GK, Peng YJ. Sympatho-adrenal activation by chronic intermittent hypoxia. Journal of Applied Physiology (Bethesda, Md. : 1985). 113: 1304-10. PMID 22723632 DOI: 10.1152/japplphysiol.00444.2012  0.6
2012 Nanduri J, Makarenko V, Reddy VD, Yuan G, Pawar A, Wang N, Khan SA, Zhang X, Kinsman B, Peng YJ, Kumar GK, Fox AP, Godley LA, Semenza GL, Prabhakar NR. Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 109: 2515-20. PMID 22232674 DOI: 10.1073/pnas.1120600109  0.6
2012 Rajamohan SB, Raghuraman G, Prabhakar NR, Kumar GK. NADPH oxidase-derived H(2)O(2) contributes to angiotensin II-induced aldosterone synthesis in human and rat adrenal cortical cells. Antioxidants & Redox Signaling. 17: 445-59. PMID 22214405 DOI: 10.1089/ars.2011.4176  0.6
2012 Peng YJ, Nanduri J, Zhang X, Wang N, Raghuraman G, Seagard J, Kumar GK, Prabhakar NR. Endothelin-1 mediates attenuated carotid baroreceptor activity by intermittent hypoxia. Journal of Applied Physiology (Bethesda, Md. : 1985). 112: 187-96. PMID 22016368 DOI: 10.1152/japplphysiol.00529.2011  0.6
2011 Garcia AJ, Khan SA, Kumar GK, Prabhakar NR, Ramirez JM. Hydrogen peroxide differentially affects activity in the pre-Bötzinger complex and hippocampus. Journal of Neurophysiology. 106: 3045-55. PMID 21849609 DOI: 10.1152/jn.00550.2010  0.6
2011 Peng YJ, Raghuraman G, Khan SA, Kumar GK, Prabhakar NR. Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 964-70. PMID 21636565 DOI: 10.1152/japplphysiol.00022.2011  0.6
2011 Peng YJ, Nanduri J, Khan SA, Yuan G, Wang N, Kinsman B, Vaddi DR, Kumar GK, Garcia JA, Semenza GL, Prabhakar NR. Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension. Proceedings of the National Academy of Sciences of the United States of America. 108: 3065-70. PMID 21288809 DOI: 10.1073/pnas.1100064108  0.6
2011 Kumar GK. Hypoxia. 3. Hypoxia and neurotransmitter synthesis. American Journal of Physiology. Cell Physiology. 300: C743-51. PMID 21270298 DOI: 10.1152/ajpcell.00019.2011  0.6
2011 Raghuraman G, Kalari A, Dhingra R, Prabhakar NR, Kumar GK. Enhanced neuropeptide Y synthesis during intermittent hypoxia in the rat adrenal medulla: role of reactive oxygen species-dependent alterations in precursor peptide processing. Antioxidants & Redox Signaling. 14: 1179-90. PMID 20836657 DOI: 10.1089/ars.2010.3353  0.6
2011 Khan SA, Nanduri J, Yuan G, Kinsman B, Kumar GK, Joseph J, Kalyanaraman B, Prabhakar NR. NADPH oxidase 2 mediates intermittent hypoxia-induced mitochondrial complex I inhibition: relevance to blood pressure changes in rats. Antioxidants & Redox Signaling. 14: 533-42. PMID 20618070 DOI: 10.1089/ars.2010.3213  0.6
2011 Kumar GK, Prabhakar NR. Neurotransmitter synthesis during intermittent hypoxia: Role of reactive oxygen species-dependent posttranslational protein modifications Intermittent Hypoxia: From Molecular Mechanisms to Clinical Applications. 345-354.  0.6
2010 Raghuraman G, Prabhakar NR, Kumar GK. Post-translational modification of glutamic acid decarboxylase 67 by intermittent hypoxia: evidence for the involvement of dopamine D1 receptor signaling. Journal of Neurochemistry. 115: 1568-78. PMID 20969567 DOI: 10.1111/j.1471-4159.2010.07063.x  0.6
2010 Prabhakar NR, Kumar GK. Mechanisms of sympathetic activation and blood pressure elevation by intermittent hypoxia. Respiratory Physiology & Neurobiology. 174: 156-61. PMID 20804865 DOI: 10.1016/j.resp.2010.08.021  0.6
2010 Prabhakar NR, Kumar GK, Nanduri J. Intermittent hypoxia augments acute hypoxic sensing via HIF-mediated ROS. Respiratory Physiology & Neurobiology. 174: 230-4. PMID 20804864 DOI: 10.1016/j.resp.2010.08.022  0.6
2010 Souvannakitti D, Nanduri J, Yuan G, Kumar GK, Fox AP, Prabhakar NR. NADPH oxidase-dependent regulation of T-type Ca2+ channels and ryanodine receptors mediate the augmented exocytosis of catecholamines from intermittent hypoxia-treated neonatal rat chromaffin cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10763-72. PMID 20705601 DOI: 10.1523/JNEUROSCI.2307-10.2010  0.6
2010 Souvannakitti D, Kuri B, Yuan G, Pawar A, Kumar GK, Smith C, Fox AP, Prabhakar NR. Neonatal intermittent hypoxia impairs neuronal nicotinic receptor expression and function in adrenal chromaffin cells. American Journal of Physiology. Cell Physiology. 299: C381-8. PMID 20664070 DOI: 10.1152/ajpcell.00159.2010  0.6
2010 Peng YJ, Nanduri J, Raghuraman G, Souvannakitti D, Gadalla MM, Kumar GK, Snyder SH, Prabhakar NR. H2S mediates O2 sensing in the carotid body. Proceedings of the National Academy of Sciences of the United States of America. 107: 10719-24. PMID 20556885 DOI: 10.1073/pnas.1005866107  0.6
2009 Prabhakar NR, Kumar GK, Nanduri J. Intermittent hypoxia-mediated plasticity of acute O2 sensing requires altered red-ox regulation by HIF-1 and HIF-2. Annals of the New York Academy of Sciences. 1177: 162-8. PMID 19845618 DOI: 10.1111/j.1749-6632.2009.05034.x  0.6
2009 Souvannakitti D, Kumar GK, Fox A, Prabhakar NR. Contrasting effects of intermittent and continuous hypoxia on low O 2 evoked catecholamine secretion from neonatal rat chromaffin cells Advances in Experimental Medicine and Biology. 648: 345-349. PMID 19536498 DOI: 10.1007/978-90-481-2259-2_39  0.6
2009 Prabhakar NR, Peng YJ, Kumar GK, Nanduri J, Di Giulio C, Lahiri S. Long-term regulation of carotid body function: Acclimatization and adaptation Advances in Experimental Medicine and Biology. 648: 307-317. PMID 19536494 DOI: 10.1007/978-90-481-2259-2_35  0.6
2009 Peng YJ, Nanduri J, Yuan G, Wang N, Deneris E, Pendyala S, Natarajan V, Kumar GK, Prabhakar NR. NADPH oxidase is required for the sensory plasticity of the carotid body by chronic intermittent hypoxia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4903-10. PMID 19369559 DOI: 10.1523/JNEUROSCI.4768-08.2009  0.6
2009 Souvannakitti D, Kumar GK, Fox A, Prabhakar NR. Neonatal intermittent hypoxia leads to long-lasting facilitation of acute hypoxia-evoked catecholamine secretion from rat chromaffin cells Journal of Neurophysiology. 101: 2837-2846. PMID 19339466 DOI: 10.1152/jn.00036.2009  0.6
2009 Raghuraman G, Rai V, Peng YJ, Prabhakar NR, Kumar GK. Pattern-specific sustained activation of tyrosine hydroxylase by intermittent hypoxia: role of reactive oxygen species-dependent downregulation of protein phosphatase 2A and upregulation of protein kinases. Antioxidants & Redox Signaling. 11: 1777-89. PMID 19335094 DOI: 10.1089/ars.2008.2368  0.6
2009 Nanduri J, Wang N, Yuan G, Khan SA, Souvannakitti D, Peng YJ, Kumar GK, Garcia JA, Prabhakar NR. Intermittent hypoxia degrades HIF-2alpha via calpains resulting in oxidative stress: implications for recurrent apnea-induced morbidities. Proceedings of the National Academy of Sciences of the United States of America. 106: 1199-204. PMID 19147445 DOI: 10.1073/pnas.0811018106  0.6
2009 Pawar A, Nanduri J, Yuan G, Khan SA, Wang N, Kumar GK, Prabhakar NR. Reactive oxygen species-dependent endothelin signaling is required for augmented hypoxic sensory response of the neonatal carotid body by intermittent hypoxia. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R735-42. PMID 19109370 DOI: 10.1152/ajpregu.90490.2008  0.6
2009 Sharma SD, Raghuraman G, Lee MS, Prabhakar NR, Kumar GK. Intermittent hypoxia activates peptidylglycine alpha-amidating monooxygenase in rat brain stem via reactive oxygen species-mediated proteolytic processing. Journal of Applied Physiology (Bethesda, Md. : 1985). 106: 12-9. PMID 18818385 DOI: 10.1152/japplphysiol.90702.2008  0.6
2008 Nanduri J, Yuan G, Kumar GK, Semenza GL, Prabhakar NR. Transcriptional responses to intermittent hypoxia. Respiratory Physiology & Neurobiology. 164: 277-81. PMID 18692603 DOI: 10.1016/j.resp.2008.07.006  0.6
2008 Kumar GK, Prabhakar NR. Post-translational modification of proteins during intermittent hypoxia. Respiratory Physiology & Neurobiology. 164: 272-6. PMID 18602876 DOI: 10.1016/j.resp.2008.05.017  0.6
2007 Prabhakar NR, Kumar GK, Nanduri J, Semenza GL. ROS signaling in systemic and cellular responses to chronic intermittent hypoxia. Antioxidants & Redox Signaling. 9: 1397-403. PMID 17627465 DOI: 10.1089/ars.2007.1732  0.6
2007 Prabhakar NR, Peng YJ, Kumar GK, Pawar A. Altered carotid body function by intermittent hypoxia in neonates and adults: relevance to recurrent apneas. Respiratory Physiology & Neurobiology. 157: 148-53. PMID 17317339 DOI: 10.1016/j.resp.2006.12.009  0.6
2007 Prabhakar NR, Dick TE, Nanduri J, Kumar GK. Systemic, cellular and molecular analysis of chemoreflex-mediated sympathoexcitation by chronic intermittent hypoxia. Experimental Physiology. 92: 39-44. PMID 17124274 DOI: 10.1113/expphysiol.2006.036434  0.6
2006 Peng YJ, Yuan G, Ramakrishnan D, Sharma SD, Bosch-Marce M, Kumar GK, Semenza GL, Prabhakar NR. Heterozygous HIF-1alpha deficiency impairs carotid body-mediated systemic responses and reactive oxygen species generation in mice exposed to intermittent hypoxia. The Journal of Physiology. 577: 705-16. PMID 16973705 DOI: 10.1113/jphysiol.2006.114033  0.6
2006 Peng YJ, Yuan G, Jacono FJ, Kumar GK, Prabhakar NR. 5-HT evokes sensory long-term facilitation of rodent carotid body via activation of NADPH oxidase. The Journal of Physiology. 576: 289-95. PMID 16887872 DOI: 10.1113/jphysiol.2006.116020  0.6
2006 Kumar GK, Rai V, Sharma SD, Ramakrishnan DP, Peng YJ, Souvannakitti D, Prabhakar NR. Chronic intermittent hypoxia induces hypoxia-evoked catecholamine efflux in adult rat adrenal medulla via oxidative stress. The Journal of Physiology. 575: 229-39. PMID 16777938 DOI: 10.1113/jphysiol.2006.112524  0.6
2006 Prabhakar NR, Peng YJ, Yuan G, Kumar GK. Reactive oxygen species facilitate oxygen sensing. Novartis Foundation Symposium. 272: 95-9; discussion 100. PMID 16686431 DOI: 10.1002/9780470035009.ch8  0.6
2006 Prabhakar NR, Kumar GK. Oxygen sensing in health and disease Current Respiratory Medicine Reviews. 2: 427-429. DOI: 10.2174/157339806778777258  0.6
2005 Prabhakar NR, Peng YJ, Jacono FJ, Kumar GK, Dick TE. Cardiovascular alterations by chronic intermittent hypoxia: importance of carotid body chemoreflexes. Clinical and Experimental Pharmacology & Physiology. 32: 447-9. PMID 15854156 DOI: 10.1111/j.1440-1681.2005.04209.x  0.6
2005 Jacono FJ, Peng YJ, Kumar GK, Prabhakar NR. Modulation of the hypoxic sensory response of the carotid body by 5-hydroxytryptamine: Role of the 5-HT2 receptor Respiratory Physiology and Neurobiology. 145: 135-142. PMID 15705529 DOI: 10.1016/j.resp.2004.10.002  0.6
2004 Prabhakar NR, Kumar GK. Oxidative stress in the systemic and cellular responses to intermittent hypoxia. Biological Chemistry. 385: 217-21. PMID 15134334 DOI: 10.1515/BC.2004.015  0.6
2004 Yuan G, Adhikary G, McCormick AA, Holcroft JJ, Kumar GK, Prabhakar NR. Role of oxidative stress in intermittent hypoxia-induced immediate early gene activation in rat PC12 cells. The Journal of Physiology. 557: 773-83. PMID 15107478 DOI: 10.1113/jphysiol.2003.058503  0.6
2004 Prabhakar NR, Peng YJ, Overholt JL, Kumar GK. Detection of oxygen sensing during intermittent hypoxia. Methods in Enzymology. 381: 107-20. PMID 15063668 DOI: 10.1016/S0076-6879(04)81006-1  0.6
2004 Kumar GK, Klein JB. Analysis of expression and posttranslational modification of proteins during hypoxia. Journal of Applied Physiology (Bethesda, Md. : 1985). 96: 1178-86; discussion . PMID 14766768 DOI: 10.1152/japplphysiol.00818.2003  0.6
2004 Kim DK, Natarajan N, Prabhakar NR, Kumar GK. Facilitation of dopamine and acetylcholine release by intermittent hypoxia in PC12 cells: involvement of calcium and reactive oxygen species. Journal of Applied Physiology (Bethesda, Md. : 1985). 96: 1206-15; discussion . PMID 14657041 DOI: 10.1152/japplphysiol.00879.2003  0.6
2004 Kim DK, Prabhakar NR, Kumar GK. Acetylcholine release from the carotid body by hypoxia: evidence for the involvement of autoinhibitory receptors. Journal of Applied Physiology (Bethesda, Md. : 1985). 96: 376-83. PMID 12923121 DOI: 10.1152/japplphysiol.00726.2003  0.6
2003 Peng Y, Yuan G, Overholt JL, Kumar GK, Prabhakar NR. Systemic and cellular responses to intermittent hypoxia: evidence for oxidative stress and mitochondrial dysfunction. Advances in Experimental Medicine and Biology. 536: 559-64. PMID 14635713  0.6
2003 Kim DK, Summers BA, Prabhakar NR, Kumar GK. Hypoxia does not uniformly facilitate the release of multiple transmitters from the carotid body. Advances in Experimental Medicine and Biology. 536: 291-6. PMID 14635680  0.6
2003 Peng YJ, Overholt JL, Kline D, Kumar GK, Prabhakar NR. Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas. Proceedings of the National Academy of Sciences of the United States of America. 100: 10073-8. PMID 12907705 DOI: 10.1073/pnas.1734109100  0.6
2003 Kumar GK, Prabhakar NR. Tachykinins in the control of breathing by hypoxia: pre- and post-genomic era. Respiratory Physiology & Neurobiology. 135: 145-54. PMID 12809615 DOI: 10.1016/S1569-9048(03)00033-8  0.6
2003 Kumar GK, Kim DK, Lee MS, Ramachandran R, Prabhakar NR. Activation of tyrosine hydroxylase by intermittent hypoxia: involvement of serine phosphorylation. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 536-44. PMID 12692140 DOI: 10.1152/japplphysiol.00186.2003  0.6
2001 Kim DK, Summers BA, Prabhakar NR, Kumar GK. Neurotransmitter release from the rabbit carotid body: differential effects of hypoxia on substance P and acetylcholine release. Advances in Experimental Medicine and Biology. 499: 39-43. PMID 11729913  0.6
2001 Adhikary G, Kline D, Yuan G, Kumar GK, Simonson MS, Cherniack NS, Prabhakar NR. Gene regulation during intermittent hypoxia: evidence for the involvement of reactive oxygen species. Advances in Experimental Medicine and Biology. 499: 297-302. PMID 11729895  0.6
2001 Kim DK, Oh EK, Summers BA, Prabhakar NR, Kumar GK. Release of substance P by low oxygen in the rabbit carotid body: evidence for the involvement of calcium channels. Brain Research. 892: 359-69. PMID 11172784 DOI: 10.1016/S0006-8993(00)03272-8  0.6
2000 Kumar GK, Ru-Kou Y, Overholt JL, Prabhakar NR. Role of substance P in neutral endopeptidase modulation of hypoxic response of the carotid body Advances in Experimental Medicine and Biology. 475: 705-713. PMID 10849712  0.6
2000 Kumar GK, Oh EK, Lee MS. Interaction between catecholamines and neuropeptides in the carotid body: evidence for dopamine modulation of neutral endopeptidase activity. Advances in Experimental Medicine and Biology. 475: 507-15. PMID 10849691  0.6
2000 Kumar GK, Kou YR, Overholt JL, Prabhakar NR. Involvement of substance P in neutral endopeptidase modulation of carotid body sensory responses to hypoxia Journal of Applied Physiology. 88: 195-202. PMID 10642381  0.6
1999 Haqqi TM, Anthony DD, Gupta S, Ahmad N, Lee MS, Kumar GK, Mukhtar H. Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea. Proceedings of the National Academy of Sciences of the United States of America. 96: 4524-9. PMID 10200295 DOI: 10.1073/pnas.96.8.4524  0.6
1998 Kumar GK, Overholt JL, Bright GR, Hui KY, Lu H, Gratzl M, Prabhakar NR. Release of dopamine and norepinephrine by hypoxia from PC-12 cells. The American Journal of Physiology. 274: C1592-600. PMID 9611124  0.6
1997 Kumar GK. Peptidases of the peripheral chemoreceptors: Biochemical, immunological, in vitro hydrolytic studies and electron microscopic analysis of neutral endopeptidase-like activity of the carotid body Brain Research. 748: 39-50. PMID 9067443 DOI: 10.1016/S0006-8993(96)01242-5  0.6
1997 Dakappagari H, Kumar GK. Structural analysis of soluble neutral endopeptidase of the carotid body Faseb Journal. 11.  0.6
1997 Veerappan GR, Napora TE, Luther C, Kumar GK. Regulation of enzymes of neuropeptide metabolism by hypoxia: Evidence for tissue-specific mechanism(S) Faseb Journal. 11.  0.6
1997 Kumar GK, Shenov BC, Napora TE. Evidence for the occurrence of calcium-activated neutral protease in the carotid body Faseb Journal. 11.  0.6
1996 Prabhakar NR, Pieramici SF, Premkumar DR, Kumar GK, Kalaria RN. Activation of nitric oxide synthase gene expression by hypoxia in central and peripheral neurons. Brain Research. Molecular Brain Research. 43: 341-6. PMID 9037552 DOI: 10.1016/S0169-328X(96)00222-7  0.6
1996 Prabhakar NR, Rao S, Premkumar D, Pieramici SF, Kumar GK, Kalaria RK. Regulation of neuronal nitric oxide synthase gene expression by hypoxia: Role of nitric oxide in respiratory adaptation to low pO2 Advances in Experimental Medicine and Biology. 410: 345-348. PMID 9030323  0.6
1996 Kumar GK. Neuropeptide processing enzymes of the carotid body: Biochemical and Immunological Characterization of Carboxypeptidase Activity Advances in Experimental Medicine and Biology. 410: 319-323. PMID 9030318  0.6
1996 Zakharov SI, Pieramici S, Kumar GK, Prabhakar NR, Harvey RD. Nitric oxide synthase activity in guinea pig ventricular myocytes is not involved in muscarinic inhibition of cAMP-regulated ion channels Circulation Research. 78: 925-935. PMID 8620613  0.6
1996 Kumar GK, Overholt JL, Prabhalar NR. Role of L-type Ca2+- channels in hypoxia-induced norepinepbrine and dopamine release in PC-12 cells Faseb Journal. 10.  0.6
1995 Prabhakar NR, Kou YR, Kumar GK. G proteins in carotid body chemoreception Biological Signals. 4: 271-276. PMID 8704827 DOI: 10.1159/000109452  0.6
1995 Prabhakar NR, Gouda E, Kumar GK, Kou YR. Analysis of carotid chemoreceptor responses to substance P analogue in anaesthetized cats Journal of the Autonomic Nervous System. 52: 43-50. PMID 7540190 DOI: 10.1016/0165-1838(94)00143-8  0.6
1994 Kumar GK, Prabhakar NR, Strohl KP, Thomas A, Cragg PA. Low PO2 dependency of neutral endopeptidase and acetylcholinesterase activities of the rat carotid body Advances in Experimental Medicine and Biology. 360: 217-220. PMID 7872091  0.6
1993 Shenoy BC, Magner WJ, Kumar GK, Phillips NFB, Haase FC, Samols D. The Nonbiotinylated Form of the 1.3 S Subunit of Transcarboxylase Binds to Avidin (Monomeric)-Agarose: Purification and Separation from the Biotinylated 1.3 S Subunit Protein Expression and Purification. 4: 85-94. PMID 8425112 DOI: 10.1006/prep.1993.1013  0.6
1993 Shenoy BC, Kumar GK, Samols D. Dissection of the biotinyl subunit of transcarboxylase into regions essential for activity and assembly Journal of Biological Chemistry. 268: 2232-2238. PMID 8420991  0.6
1993 Thornton CG, Kumar GK, Haase FC, Phillips NF, Woo SB, Park VM, Magner WJ, Shenoy BC, Wood HG, Samols D. Primary structure of the monomer of the 12S subunit of transcarboxylase as deduced from DNA and characterization of the product expressed in Escherichia coli. Journal of Bacteriology. 175: 5301-8. PMID 8366018  0.6
1993 Shenoy BC, Samols D, Kumar GK. The Conserved Methionines of the 1.3 S Biotinyl Subunit of Transcarboxylase: Effect of Mutations on Conformation and Activity Archives of Biochemistry and Biophysics. 304: 359-366. PMID 8346913 DOI: 10.1006/abbi.1993.1362  0.6
1993 Woo SB, Shenoy BC, Wood HG, Magner WJ, Kumar GK, Beegen H, Samols D. Effect of deletion from the carboxyl terminus of the 12 S subunit on activity of transcarboxylase. The Journal of Biological Chemistry. 268: 16413-9. PMID 8344927  0.6
1993 Shanmugasundaram T, Sundaresh CS, Kumar GK. Identification of a cysteine involved in the interaction between carbon monoxide dehydrogenase and corrinoid/Fe-S protein from Clostridium thermoaceticum Febs Letters. 326: 281-284. PMID 8325380 DOI: 10.1016/0014-5793(93)81808-D  0.6
1993 Prabhakar NR, Kumar GK, Chang Ho Chang, Agani FH, Haxhiu MA. Nitric oxide in the sensory function of the carotid body Brain Research. 625: 16-22. PMID 7694772 DOI: 10.1016/0006-8993(93)90132-7  0.6
1992 Shenoy BC, Xie Y, Park VL, Kumar GK, Beegen H, Wood HG, Samols D. The importance of methionine residues for the catalysis of the biotin enzyme, transcarboxylase. Analysis by site-directed mutagenesis. The Journal of Biological Chemistry. 267: 18407-12. PMID 1526981  0.6
1992 Haxhiu-Poskurica B, Haxhiu MA, Kumar GK, Miller MJ, Martin RJ. Tracheal smooth muscle responses to substance P and neurokinin A in the piglet Journal of Applied Physiology. 72: 1090-1095. PMID 1373711  0.6
1990 Kumar GK, Runold M, Ghai RD, Cherniack NS, Prabhakar NR. Occurrence of neutral endopeptidase activity in the cat carotid body and its significance in chemoreception. Brain Research. 517: 341-3. PMID 2376002 DOI: 10.1016/0006-8993(90)91047-K  0.6
1989 Shanmugasundaram T, Kumar GK, Shenoy BC, Wood HG. Chemical modification of the functional arginine residues of carbon monoxide dehydrogenase from Clostridium thermoaceticum. Biochemistry. 28: 7112-6. PMID 2819052  0.6
1989 Prabhakar NR, Runold M, Kumar GK, Cherniack NS, Scarpa A. Substance P and mitochondrial oxygen consumption: evidence for a direct intracellular role for the peptide. Peptides. 10: 1003-6. PMID 2481845 DOI: 10.1016/0196-9781(89)90182-4  0.6
1989 Prabhakar NR, Landis SC, Kumar GK, Mullikin-Kilpatrick D, Cherniack NS, Leeman S. Substance P and neurokinin A in the cat carotid body: localization, exogenous effects and changes in content in response to arterial pO2. Brain Research. 481: 205-14. PMID 2470465 DOI: 10.1016/0006-8993(89)90795-6  0.6
1988 Shanmugasundaram T, Kumar GK, Wood HG. Involvement of tryptophan residues at the coenzyme A binding site of carbon monoxide dehydrogenase from Clostridium thermoaceticum. Biochemistry. 27: 6499-503. PMID 3219350  0.6
1988 Kumar GK, Haase FC, Phillips NF, Wood HG. Involvement and identification of a tryptophanyl residue at the pyruvate binding site of transcarboxylase. Biochemistry. 27: 5978-83. PMID 3191103  0.6
1988 Kumar GK, Beegen H, Wood HG. Involvement of tryptophans at the catalytic and subunit-binding domains of transcarboxylase. Biochemistry. 27: 5972-8. PMID 3191102  0.6
1988 Shenoy BC, Paranjape S, Murtif VL, Kumar GK, Samols D, Wood HG. Effect of mutations at Met-88 and Met-90 on the biotination of Lys-89 of the apo 1.3S subunit of transcarboxylase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2: 2505-11. PMID 3131174  0.6
1988 Samols D, Thornton CG, Murtif VL, Kumar GK, Haase FC, Wood HG. Evolutionary conservation among biotin enzymes. The Journal of Biological Chemistry. 263: 6461-4. PMID 2896195  0.6
1985 Wood HG, Kumar GK. Transcarboxylase: its quaternary structure and the role of the biotinyl subunit in the assembly of the enzyme and in catalysis. Annals of the New York Academy of Sciences. 447: 1-22. PMID 3893281  0.6
1984 Kumar GK, Haase CF. Chemical cross-linking of transcarboxylase: Sequences of the outer subunit which bind to the biotinyl subunit near the biotin site Federation Proceedings. 43.  0.6
1982 Kumar GK, Bahler CR, Wood HG, Merrifield RB. The amino acid sequences of the biotinyl subunit essential for the association of transcarboxylase. The Journal of Biological Chemistry. 257: 13828-34. PMID 7142178  0.6
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