Luke I. Szweda - Publications

Case Western Reserve University School of Medicine, Cleveland, OH, United States 

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kim SY, Zhang X, Schiattarella GG, Altamirano F, Ramos TAR, French KM, Jiang N, Szweda PA, Evers BM, May HI, Luo X, Li H, Szweda LI, Maracaja-Coutinho V, Lavandero S, et al. Epigenetic Reader BRD4 Governs Nucleus-encoded Mitochondrial Transcriptome to Regulate Cardiac Function. Circulation. PMID 33113340 DOI: 10.1161/CIRCULATIONAHA.120.047239  0.52
2019 Newhardt MF, Batushansky A, Matsuzaki S, Young ZT, West M, Chin NC, Szweda LI, Kinter M, Humphries KM. Enhancing cardiac glycolysis causes an increase in PDK4 content in response to short term high fat diet. The Journal of Biological Chemistry. PMID 31562244 DOI: 10.1074/jbc.RA119.010371  0.92
2018 Schafer C, Young ZT, Makarewich CA, Elnwasany A, Kinter CS, Kinter M, Szweda LI. Coenzyme A-mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice. The Journal of Biological Chemistry. PMID 29540486 DOI: 10.1074/jbc.RA117.000268  0.32
2018 Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, et al. Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes. Molecular Metabolism. PMID 29398615 DOI: 10.1016/j.molmet.2018.01.013  0.92
2017 Pearsall EA, Cheng R, Zhou K, Takahashi Y, Matlock HG, Vadvalkar SS, Shin Y, Fredrick TW, Gantner ML, Meng S, Fu Z, Gong Y, Kinter M, Humphries KM, Szweda LI, et al. PPARα is essential for retinal lipid metabolism and neuronal survival. Bmc Biology. 15: 113. PMID 29183319 DOI: 10.1186/s12915-017-0451-x  0.92
2016 Crewe C, Schafer C, Lee I, Kinter M, Szweda LI. Regulation of Pyruvate Dehydrogenase Kinase 4 in the Heart Through Degradation by the Lon Protease in Response to Mitochondrial Substrate Availability. The Journal of Biological Chemistry. PMID 27856638 DOI: 10.1074/jbc.M116.754127  0.32
2016 Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah A, Zhang H, Faber JE, Kinter MT, Szweda LI, Xing C, Deberardinis R, Oz O, Lu Z, et al. Hypoxia induces heart regeneration in adult mice. Nature. PMID 27798600 DOI: 10.1038/nature20173  0.48
2016 Rindler PM, Cacciola A, Kinter M, Szweda LI. Catalase-Dependent H2O2 Consumption by Cardiac Mitochondria and Redox-Mediated Loss in Insulin Signaling. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00066.2016. PMID 27614223 DOI: 10.1152/ajpheart.00066.2016  0.32
2015 Griffin TM, Humphries KM, Kinter M, Lim HY, Szweda LI. Nutrient sensing and utilization: Getting to the heart of metabolic flexibility. Biochimie. PMID 26476002 DOI: 10.1016/j.biochi.2015.10.013  1
2015 Fernandes J, Weddle A, Kinter CS, Humphries KM, Mather T, Szweda LI, Kinter M. Lysine Acetylation Activates Mitochondrial Aconitase in the Heart. Biochemistry. 54: 4008-18. PMID 26061789 DOI: 10.1021/acs.biochem.5b00375  0.92
2015 Fernandes J, Weddle A, Kinter CS, Humphries KM, Mather T, Szweda LI, Kinter M. Lysine Acetylation Activates Mitochondrial Aconitase in the Heart Biochemistry. 54: 4008-4018. DOI: 10.1021/acs.biochem.5b00375  1
2014 Yao L, Heuser-Baker J, Herlea-Pana O, Zhang N, Szweda LI, Griffin TM, Barlic-Dicen J. Deficiency in adipocyte chemokine receptor CXCR4 exacerbates obesity and compromises thermoregulatory responses of brown adipose tissue in a mouse model of diet-induced obesity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4534-50. PMID 25016030 DOI: 10.1096/fj.14-249797  0.32
2014 Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, ... ... Szweda LI, et al. The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. Cell. 157: 565-79. PMID 24766806 DOI: 10.1016/j.cell.2014.03.032  1
2013 Crewe C, Kinter M, Szweda LI. Rapid inhibition of pyruvate dehydrogenase: an initiating event in high dietary fat-induced loss of metabolic flexibility in the heart. Plos One. 8: e77280. PMID 24116221 DOI: 10.1371/journal.pone.0077280  1
2013 Hardas SS, Sultana R, Clark AM, Beckett TL, Szweda LI, Murphy MP, Butterfield DA. Oxidative modification of lipoic acid by HNE in Alzheimer disease brain. Redox Biology. 1: 80-5. PMID 24024140 DOI: 10.1016/j.redox.2013.01.002  1
2013 Rindler PM, Crewe CL, Fernandes J, Kinter M, Szweda LI. Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria. American Journal of Physiology. Heart and Circulatory Physiology. 305: H634-43. PMID 23792672 DOI: 10.1152/ajpheart.00799.2012  1
2013 Allen BG, Bhatia SK, Buatti JM, Brandt KE, Lindholm KE, Button AM, Szweda LI, Smith BJ, Spitz DR, Fath MA. Ketogenic diets enhance oxidative stress and radio-chemo-therapy responses in lung cancer xenografts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3905-13. PMID 23743570 DOI: 10.1158/1078-0432.CCR-12-0287  1
2013 McLain AL, Cormier PJ, Kinter M, Szweda LI. Glutathionylation of α-ketoglutarate dehydrogenase: the chemical nature and relative susceptibility of the cofactor lipoic acid to modification. Free Radical Biology & Medicine. 61: 161-9. PMID 23567190 DOI: 10.1016/j.freeradbiomed.2013.03.020  1
2013 Perry EA, Castellani RJ, Moreira PI, Nunomura A, Lui Q, Harris PL, Sayre LM, Szweda PA, Szweda LI, Zhu X, Smith MA, Perry G. Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links. Free Radical Research. 47: 507-10. PMID 23566300 DOI: 10.3109/10715762.2013.794265  1
2013 Rindler PM, Plafker SM, Szweda LI, Kinter M. High dietary fat selectively increases catalase expression within cardiac mitochondria. The Journal of Biological Chemistry. 288: 1979-90. PMID 23204527 DOI: 10.1074/jbc.M112.412890  1
2013 MacDonald MJ, Langberg EC, Tibell A, Sabat G, Kendrick MA, Szweda LI, Ostenson CG. Identification of ATP synthase as a lipid peroxide protein adduct in pancreatic islets from humans with and without type 2 diabetes mellitus (Journal of Clinical Endocrinology and Metabolism (2013) 98, (E727-E731) DOI: 10.1210/jc.2012-4203) Journal of Clinical Endocrinology and Metabolism. 98: 3091. DOI: 10.1210/jc.2013-2189  1
2012 Kinter CS, Lundie JM, Patel H, Rindler PM, Szweda LI, Kinter M. A quantitative proteomic profile of the Nrf2-mediated antioxidant response of macrophages to oxidized LDL determined by multiplexed selected reaction monitoring. Plos One. 7: e50016. PMID 23166812 DOI: 10.1371/journal.pone.0050016  1
2012 Plafker SM, O'Mealey GB, Szweda LI. Mechanisms for countering oxidative stress and damage in retinal pigment epithelium. International Review of Cell and Molecular Biology. 298: 135-77. PMID 22878106 DOI: 10.1016/B978-0-12-394309-5.00004-3  1
2012 Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PL, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radical Biology & Medicine. 52: 699-704. PMID 22137893 DOI: 10.1016/j.freeradbiomed.2011.11.004  1
2011 Dasuri K, Zhang L, Ebenezer P, Fernandez-Kim SO, Bruce-Keller AJ, Szweda LI, Keller JN. Proteasome alterations during adipose differentiation and aging: links to impaired adipocyte differentiation and development of oxidative stress. Free Radical Biology & Medicine. 51: 1727-35. PMID 21871954 DOI: 10.1016/j.freeradbiomed.2011.08.001  1
2011 McLain AL, Szweda PA, Szweda LI. α-Ketoglutarate dehydrogenase: a mitochondrial redox sensor. Free Radical Research. 45: 29-36. PMID 21110783 DOI: 10.3109/10715762.2010.534163  1
2010 Cussiol JR, Alegria TG, Szweda LI, Netto LE. Ohr (organic hydroperoxide resistance protein) possesses a previously undescribed activity, lipoyl-dependent peroxidase. The Journal of Biological Chemistry. 285: 21943-50. PMID 20463026 DOI: 10.1074/jbc.M110.117283  1
2010 Churchill EN, Ferreira JC, Brum PC, Szweda LI, Mochly-Rosen D. Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion. Cardiovascular Research. 85: 385-94. PMID 19820255 DOI: 10.1093/cvr/cvp334  1
2009 Matsuzaki S, Szweda PA, Szweda LI, Humphries KM. Regulated production of free radicals by the mitochondrial electron transport chain: Cardiac ischemic preconditioning. Advanced Drug Delivery Reviews. 61: 1324-31. PMID 19716389 DOI: 10.1016/j.addr.2009.05.008  1
2009 Matsuzaki S, Szweda LI, Humphries KM. Mitochondrial superoxide production and respiratory activity: biphasic response to ischemic duration. Archives of Biochemistry and Biophysics. 484: 87-93. PMID 19467633 DOI: 10.1016/  1
2008 Wu M, Chen Y, Wilson K, Chirindel A, Ihnat MA, Yu Y, Boulton ME, Szweda LI, Ma JX, Lyons TJ. Intraretinal leakage and oxidation of LDL in diabetic retinopathy. Investigative Ophthalmology & Visual Science. 49: 2679-85. PMID 18362112 DOI: 10.1167/iovs.07-1440  1
2008 Martin CM, Ferdous A, Gallardo T, Humphries C, Sadek H, Caprioli A, Garcia JA, Szweda LI, Garry MG, Garry DJ. Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side population cells. Circulation Research. 102: 1075-81. PMID 18356544 DOI: 10.1161/CIRCRESAHA.107.161729  1
2008 Applegate MA, Humphries KM, Szweda LI. Reversible inhibition of alpha-ketoglutarate dehydrogenase by hydrogen peroxide: glutathionylation and protection of lipoic acid. Biochemistry. 47: 473-8. PMID 18081316 DOI: 10.1021/bi7017464  1
2007 Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Autophagocytosis of mitochondria is prominent in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 66: 525-32. PMID 17549012 DOI: 10.1097/01.jnen.0000240476.73532.b0  1
2007 Oktay Y, Dioum E, Matsuzaki S, Ding K, Yan LJ, Haller RG, Szweda LI, Garcia JA. Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin. The Journal of Biological Chemistry. 282: 11750-6. PMID 17322295 DOI: 10.1074/jbc.M611133200  1
2007 Yu X, Tesiram YA, Towner RA, Abbott A, Patterson E, Huang S, Garrett MW, Chandrasekaran S, Matsuzaki S, Szweda LI, Gordon BE, Kem DC. Early myocardial dysfunction in streptozotocin-induced diabetic mice: a study using in vivo magnetic resonance imaging (MRI). Cardiovascular Diabetology. 6: 6. PMID 17309798 DOI: 10.1186/1475-2840-6-6  1
2007 Matsuzaki S, Szweda LI. Inhibition of complex I by Ca2+ reduces electron transport activity and the rate of superoxide anion production in cardiac submitochondrial particles. Biochemistry. 46: 1350-7. PMID 17260964 DOI: 10.1021/bi0617916  1
2006 Humphries KM, Szweda PA, Szweda LI. Aging: a shift from redox regulation to oxidative damage. Free Radical Research. 40: 1239-43. PMID 17090412 DOI: 10.1080/10715760600913184  1
2006 Haynes RL, Folkerth RD, Szweda LI, Volpe JJ, Kinney HC. Lipid peroxidation during human cerebral myelination. Journal of Neuropathology and Experimental Neurology. 65: 894-904. PMID 16957583 DOI: 10.1097/01.jnen.0000235858.56631.97  1
2006 Bulteau AL, Szweda LI, Friguet B. Mitochondrial protein oxidation and degradation in response to oxidative stress and aging. Experimental Gerontology. 41: 653-7. PMID 16677792 DOI: 10.1016/j.exger.2006.03.013  1
2006 Picot CR, Perichon M, Lundberg KC, Friguet B, Szweda LI, Petropoulos I. Alterations in mitochondrial and cytosolic methionine sulfoxide reductase activity during cardiac ischemia and reperfusion. Experimental Gerontology. 41: 663-7. PMID 16677789 DOI: 10.1016/j.exger.2006.03.011  1
2006 Lundberg KC, Szweda LI. Preconditioning prevents loss in mitochondrial function and release of cytochrome c during prolonged cardiac ischemia/reperfusion. Archives of Biochemistry and Biophysics. 453: 130-4. PMID 16546113 DOI: 10.1016/  1
2006 Farout L, Mary J, Vinh J, Szweda LI, Friguet B. Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes. Archives of Biochemistry and Biophysics. 453: 135-42. PMID 16530722 DOI: 10.1016/  1
2006 Lashin OM, Szweda PA, Szweda LI, Romani AM. Decreased complex II respiration and HNE-modified SDH subunit in diabetic heart. Free Radical Biology & Medicine. 40: 886-96. PMID 16520240 DOI: 10.1016/j.freeradbiomed.2005.10.040  1
2005 Chaiswing L, Cole MP, Ittarat W, Szweda LI, St Clair DK, Oberley TD. Manganese superoxide dismutase and inducible nitric oxide synthase modify early oxidative events in acute adriamycin-induced mitochondrial toxicity. Molecular Cancer Therapeutics. 4: 1056-64. PMID 16020663 DOI: 10.1158/1535-7163.MCT-04-0322  1
2005 Churchill EN, Szweda LI. Translocation of deltaPKC to mitochondria during cardiac reperfusion enhances superoxide anion production and induces loss in mitochondrial function. Archives of Biochemistry and Biophysics. 439: 194-9. PMID 15963450 DOI: 10.1016/  1
2005 Churchill EN, Murriel CL, Chen CH, Mochly-Rosen D, Szweda LI. Reperfusion-induced translocation of deltaPKC to cardiac mitochondria prevents pyruvate dehydrogenase reactivation. Circulation Research. 97: 78-85. PMID 15961716 DOI: 10.1161/01.RES.0000173896.32522.6e  1
2005 Mason KE, Stofan DA, Szweda LI. Inhibition of very long chain acyl-CoA dehydrogenase during cardiac ischemia. Archives of Biochemistry and Biophysics. 437: 138-43. PMID 15850553 DOI: 10.1016/  1
2005 Bulteau AL, Lundberg KC, Ikeda-Saito M, Isaya G, Szweda LI. Reversible redox-dependent modulation of mitochondrial aconitase and proteolytic activity during in vivo cardiac ischemia/reperfusion. Proceedings of the National Academy of Sciences of the United States of America. 102: 5987-91. PMID 15840721 DOI: 10.1073/pnas.0501519102  1
2005 Rosca MG, Mustata TG, Kinter MT, Ozdemir AM, Kern TS, Szweda LI, Brownlee M, Monnier VM, Weiss MF. Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation. American Journal of Physiology. Renal Physiology. 289: F420-30. PMID 15814529 DOI: 10.1152/ajprenal.00415.2004  1
2004 Chaiswing L, Cole MP, St Clair DK, Ittarat W, Szweda LI, Oberley TD. Oxidative damage precedes nitrative damage in adriamycin-induced cardiac mitochondrial injury. Toxicologic Pathology. 32: 536-47. PMID 15605432 DOI: 10.1080/01926230490502601  1
2004 Lundberg KC, Szweda LI. Initiation of mitochondrial-mediated apoptosis during cardiac reperfusion. Archives of Biochemistry and Biophysics. 432: 50-7. PMID 15519296 DOI: 10.1016/  1
2004 Nulton-Persson AC, Szweda LI, Sadek HA. Inhibition of cardiac mitochondrial respiration by salicylic acid and acetylsalicylate. Journal of Cardiovascular Pharmacology. 44: 591-5. PMID 15505497 DOI: 10.1097/00005344-200411000-00012  1
2004 Murriel CL, Churchill E, Inagaki K, Szweda LI, Mochly-Rosen D. Protein kinase Cdelta activation induces apoptosis in response to cardiac ischemia and reperfusion damage: a mechanism involving BAD and the mitochondria. The Journal of Biological Chemistry. 279: 47985-91. PMID 15339931 DOI: 10.1074/jbc.M405071200  1
2004 Bulteau AL, O'Neill HA, Kennedy MC, Ikeda-Saito M, Isaya G, Szweda LI. Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity. Science (New York, N.Y.). 305: 242-5. PMID 15247478 DOI: 10.1126/science.1098991  1
2004 Marques C, Pereira P, Taylor A, Liang JN, Reddy VN, Szweda LI, Shang F. Ubiquitin-dependent lysosomal degradation of the HNE-modified proteins in lens epithelial cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1424-6. PMID 15247152 DOI: 10.1096/fj.04-1743fje  1
2004 Sadek HA, Szweda PA, Szweda LI. Modulation of mitochondrial complex I activity by reversible Ca2+ and NADH mediated superoxide anion dependent inhibition. Biochemistry. 43: 8494-502. PMID 15222760 DOI: 10.1021/bi049803f  1
2004 Oberley TD, Xue Y, Zhao Y, Kiningham K, Szweda LI, St Clair DK. In situ reduction of oxidative damage, increased cell turnover, and delay of mitochondrial injury by overexpression of manganese superoxide dismutase in a multistage skin carcinogenesis model. Antioxidants & Redox Signaling. 6: 537-48. PMID 15130280 DOI: 10.1089/152308604773934297  1
2003 Bulteau AL, Ikeda-Saito M, Szweda LI. Redox-dependent modulation of aconitase activity in intact mitochondria. Biochemistry. 42: 14846-55. PMID 14674759 DOI: 10.1021/bi0353979  1
2003 Sadek HA, Nulton-Persson AC, Szweda PA, Szweda LI. Cardiac ischemia/reperfusion, aging, and redox-dependent alterations in mitochondrial function. Archives of Biochemistry and Biophysics. 420: 201-8. PMID 14654058 DOI: 10.1016/  1
2003 Szweda PA, Camouse M, Lundberg KC, Oberley TD, Szweda LI. Aging, lipofuscin formation, and free radical-mediated inhibition of cellular proteolytic systems. Ageing Research Reviews. 2: 383-405. PMID 14522242 DOI: 10.1016/S1568-1637(03)00028-X  1
2003 Czerski LW, Szweda PA, Szweda LI. Dissociation of cytochrome c from the inner mitochondrial membrane during cardiac ischemia. The Journal of Biological Chemistry. 278: 34499-504. PMID 12813053 DOI: 10.1074/jbc.M302021200  1
2003 Nulton-Persson AC, Starke DW, Mieyal JJ, Szweda LI. Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status. Biochemistry. 42: 4235-42. PMID 12680778 DOI: 10.1021/bi027370f  1
2003 Lucas DT, Aryal P, Szweda LI, Koch WJ, Leinwand LA. Alterations in mitochondrial function in a mouse model of hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. 284: H575-83. PMID 12414446 DOI: 10.1152/ajpheart.00619.2002  1
2002 Sadek HA, Humphries KM, Szweda PA, Szweda LI. Selective inactivation of redox-sensitive mitochondrial enzymes during cardiac reperfusion. Archives of Biochemistry and Biophysics. 406: 222-8. PMID 12361710 DOI: 10.1016/S0003-9861(02)00446-0  1
2002 Szweda PA, Tsai L, Szweda LI. Immunochemical detection of a fluorophore derived from the lipid peroxidation product 4-hydroxy-2-nonenal and lysine. Methods in Molecular Biology (Clifton, N.J.). 196: 277-90. PMID 12152206 DOI: 10.1385/1-59259-274-0:277  1
2002 Szweda PA, Friguet B, Szweda LI. Proteolysis, free radicals, and aging. Free Radical Biology & Medicine. 33: 29-36. PMID 12086679 DOI: 10.1016/S0891-5849(02)00837-7  1
2002 Rosca MG, Monnier VM, Szweda LI, Weiss MF. Alterations in renal mitochondrial respiration in response to the reactive oxoaldehyde methylglyoxal. American Journal of Physiology. Renal Physiology. 283: F52-9. PMID 12060586 DOI: 10.1152/ajprenal.00302.2001  1
2002 Bulteau AL, Szweda LI, Friguet B. Age-dependent declines in proteasome activity in the heart. Archives of Biochemistry and Biophysics. 397: 298-304. PMID 11795886 DOI: 10.1006/abbi.2001.2663  1
2002 Wataya T, Nunomura A, Smith MA, Siedlak SL, Harris PL, Shimohama S, Szweda LI, Kaminski MA, Avila J, Price DL, Cleveland DW, Sayre LM, Perry G. High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal. The Journal of Biological Chemistry. 277: 4644-8. PMID 11733539 DOI: 10.1074/jbc.M110913200  1
2001 Lauderback CM, Hackett JM, Huang FF, Keller JN, Szweda LI, Markesbery WR, Butterfield DA. The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42. Journal of Neurochemistry. 78: 413-6. PMID 11461977 DOI: 10.1046/j.1471-4159.2001.00451.x  1
2001 Bulteau AL, Lundberg KC, Humphries KM, Sadek HA, Szweda PA, Friguet B, Szweda LI. Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion. The Journal of Biological Chemistry. 276: 30057-63. PMID 11375979 DOI: 10.1074/jbc.M100142200  1
2001 Nulton-Persson AC, Szweda LI. Modulation of mitochondrial function by hydrogen peroxide. The Journal of Biological Chemistry. 276: 23357-61. PMID 11283020 DOI: 10.1074/jbc.M100320200  1
2001 Callahan LA, Stofan DA, Szweda LI, Nethery DE, Supinski GS. Free radicals alter maximal diaphragmatic mitochondrial oxygen consumption in endotoxin-induced sepsis. Free Radical Biology & Medicine. 30: 129-38. PMID 11134903 DOI: 10.1016/S0891-5849(00)00454-8  1
2000 Zainal TA, Oberley TD, Allison DB, Szweda LI, Weindruch R. Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle Faseb Journal. 14: 1825-1836. PMID 10973932  1
2000 Sasaki M, Ansari A, Pumford N, van de Water J, Leung PS, Humphries KM, Szweda LI, Nakanuma Y, Roche TE, Coppel RL, Bach JF, Gershwin ME. Comparative immunoreactivity of anti-trifluoroacetyl (TFA) antibody and anti-lipoic acid antibody in primary biliary cirrhosis: searching for a mimic. Journal of Autoimmunity. 15: 51-60. PMID 10936028 DOI: 10.1006/jaut.2000.0390  1
2000 Szweda LI, Szweda PA, Holian A. Detection of 4-hydroxy-2-nonenol adducts following lipid peroxidation from ozone exposure Methods in Enzymology. 319: 562-570. PMID 10907544  1
2000 Oberley TD, Zhong W, Szweda LI, Oberley LW. Localization of antioxidant enzymes and oxidative damage products in normal and malignant prostate epithelium Prostate. 44: 144-155. PMID 10881024 DOI: 10.1002/1097-0045(20000701)44:2<144::AID-PROS7>3.0.CO;2-G  1
1999 Yao ZX, Drieu K, Szweda LI, Papadopoulos V. Free radicals and lipid peroxidation do not mediate β-amyloid-induced neuronal cell death Brain Research. 847: 203-210. PMID 10575089 DOI: 10.1016/S0006-8993(99)02047-8  1
1999 Oberley TD, Toyokuni S, Szweda LI. Localization of hydroxynonenal protein adducts in normal human kidney and selected human kidney cancers Free Radical Biology and Medicine. 27: 695-703. PMID 10490290 DOI: 10.1016/S0891-5849(99)00117-3  1
1999 Zainal TA, Weindruch R, Szweda LI, Oberley TD. Localization of 4-hydroxy-2-nonenal-modified proteins in kidney following iron overload Free Radical Biology and Medicine. 26: 1181-1193. PMID 10381189 DOI: 10.1016/S0891-5849(98)00312-8  1
1999 Lucas DT, Szweda LI. Declines in mitochondrial respiration during cardiac reperfusion: Age-dependent inactivation of α-ketoglutarate dehydrogenase Proceedings of the National Academy of Sciences of the United States of America. 96: 6689-6693. PMID 10359773  1
1999 Rittner HL, Kaiser M, Brack A, Szweda LI, Goronzy JJ, Weyand CM. Tissue-destructive macrophages in giant cell arteritis Circulation Research. 84: 1050-1058. PMID 10325242  1
1999 Rittner HL, Hafner V, Klimiuk PA, Szweda LI, Goronzy JJ, Weyand CM. Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis Journal of Clinical Investigation. 103: 1007-1013. PMID 10194473  1
1999 Yen HC, Oberley TD, Gairola CG, Szweda LI, St. Clair DK. Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice Archives of Biochemistry and Biophysics. 362: 59-66. PMID 9917329 DOI: 10.1006/abbi.1998.1011  1
1998 Humphries KM, Szweda LI. Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal. Biochemistry. 37: 15835-41. PMID 9843389 DOI: 10.1021/bi981512h  1
1998 Tsai L, Szweda PA, Vinogradova O, Szweda LI. Structural characterization and immunochemical detection of a fluorophore derived from 4-hydroxy-2-nonenal and lysine Proceedings of the National Academy of Sciences of the United States of America. 95: 7975-7980. PMID 9653125 DOI: 10.1073/pnas.95.14.7975  1
1998 Majima HJ, Oberley TD, Furukawa K, Mattson MP, Yen HC, Szweda LI, St. Clair DK. Prevention of mitochondrial injury by manganese superoxide dismutase reveals a primary mechanism for alkaline-induced cell death Journal of Biological Chemistry. 273: 8217-8224. PMID 9525927 DOI: 10.1074/jbc.273.14.8217  1
1998 Lucas DT, Szweda LI. Cardiac reperfusion injury: Aging, lipid peroxidation, and mitochondrial dysfunction Proceedings of the National Academy of Sciences of the United States of America. 95: 510-514. PMID 9435222 DOI: 10.1073/pnas.95.2.510  1
1998 Humphries KM, Yoo Y, Szweda LI. Inhibition of NADH-linked mitochondrial respiration by 4-hydroxy-2-nonenal. Biochemistry. 37: 552-7. PMID 9425076 DOI: 10.1021/bi971958i  1
1997 Friguet B, Szweda LI. Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein Febs Letters. 405: 21-25. PMID 9094417 DOI: 10.1016/S0014-5793(97)00148-8  1
1997 Humphries KM, Szweda LI. 4-hydroxy-2-nonenal mediated declines in mitochondrial respiration Faseb Journal. 11.  1
1997 Lucas DT, Szweda LI. Cardiac reperfusion injury and aging: Lipid peroxidation and mitochondria! dysfunction Faseb Journal. 11.  1
1996 Conconi M, Szweda LI, Levine RL, Stadtman ER, Friguet B. Age-related decline of rat liver multicatalytic proteinase activity and protection from oxidative inactivation by heat-shock protein 90. Archives of Biochemistry and Biophysics. 331: 232-40. PMID 8660703 DOI: 10.1006/abbi.1996.0303  1
1996 Cohn JA, Tsai L, Friguet B, Szweda LI. Chemical characterization of a protein-4-hydroxy-2-nonenal cross-link: Immunochemical detection in mitochondria exposed to oxidative stress Archives of Biochemistry and Biophysics. 328: 158-164. PMID 8638925 DOI: 10.1006/abbi.1996.0156  1
1996 Friguet B, Conconi M, Szweda LI, Levine RL, Stadtman ER. Multicatalytic proteinase activity: age-related decline and protection from oxidative inactivation by HSP 90 Faseb Journal. 10: A1402.  1
1995 Sahakian JA, Szweda LI, Friguet B, Kitani K, Levine RL. Aging of the Liver: Proteolysis of Oxidatively Modified Glutamine Synthetase Archives of Biochemistry and Biophysics. 318: 411-417. PMID 7733671 DOI: 10.1006/abbi.1995.1248  1
1994 Friguet B, Szweda LI, Stadtman ER. Susceptibility of glucose-6-phosphate dehydrogenase modified by 4-hydroxy-2-nonenal and metal-catalyzed oxidation to proteolysis by the multicatalytic protease. Archives of Biochemistry and Biophysics. 311: 168-73. PMID 8185314 DOI: 10.1006/abbi.1994.1222  1
1994 Szweda LI. Age-related increase in liver retinyl palmitate. Relationship to lipofuscin Journal of Biological Chemistry. 269: 8712-8715. PMID 8132600  1
1994 Friguet B, Stadtman ER, Szweda LI. Modification of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Formation of cross-linked protein that inhibits the multicatalytic protease. The Journal of Biological Chemistry. 269: 21639-43. PMID 8063806  1
1993 Szweda LI, Uchida K, Tsai L, Stadtman ER. Inactivation of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Selective modification of an active-site lysine. The Journal of Biological Chemistry. 268: 3342-7. PMID 8429010  1
1993 Uchida K, Szweda LI, Chae HZ, Stadtman ER. Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 90: 8742-6. PMID 8378358  1
1992 Szweda LI, Stadtman ER. Iron-catalyzed oxidative modification of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides. Structural and functional changes. The Journal of Biological Chemistry. 267: 3096-100. PMID 1737765  1
1990 Szweda LI, Atkinson DE. Response of rat liver glutaminase to magnesium ion. Biochimica Et Biophysica Acta. 1041: 201-6. PMID 2265206 DOI: 10.1016/0167-4838(90)90066-O  1
1990 Szweda LI, Atkinson DE. Response of rat liver glutaminase to pH, ammonium, and citrate. Possible regulatory role of glutaminase in ureagenesis. The Journal of Biological Chemistry. 265: 20869-73. PMID 2249993  1
1989 Szweda LI, Atkinson DE. Response of rat liver glutaminase to pH. Mediation by phosphate and ammonium ions. The Journal of Biological Chemistry. 264: 15357-60. PMID 2768267  1
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