Fraydoon Rastinejad - Publications

University of Virginia, Charlottesville, VA 
Pharmacology, Medical Biophysics, Biochemistry

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wu D, Su X, Lu J, Li S, Hood BL, Vasile S, Potluri N, Diao X, Kim Y, Khorasanizadeh S, Rastinejad F. Bidirectional modulation of HIF-2 activity through chemical ligands. Nature Chemical Biology. PMID 30804532 DOI: 10.1038/s41589-019-0234-5  0.36
2018 Parafati M, Kirby RJ, Khorasanizadeh S, Rastinejad F, Malany S. A nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosis. Disease Models & Mechanisms. 11. PMID 30254132 DOI: 10.1242/dmm.033530  0.36
2017 Smith SH, Jayawickreme C, Rickard DJ, Nicodeme E, Bui T, Simmons C, Coquery CM, Neil J, Pryor WM, Mayhew D, Rajpal DK, Creech K, Furst S, Lee J, Wu D, ... Rastinejad F, et al. Tapinarof is a natural AhR agonist that resolves skin inflammation in mice and humans. The Journal of Investigative Dermatology. PMID 28595996 DOI: 10.1016/j.jid.2017.05.004  0.36
2016 Khorasanizadeh S, Rastinejad F. Visualizing the Architectures and Interactions of Nuclear Receptors. Endocrinology. en20161559. PMID 27704949 DOI: 10.1210/en.2016-1559  0.36
2016 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo F, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, et al. Corrigendum: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26789242 DOI: 10.1038/nature16968  0.96
2015 Huang W, Thomas B, Flynn RA, Gavzy SJ, Wu L, Kim SV, Hall JA, Miraldi ER, Ng CP, Rigo FW, Meadows S, Montoya NR, Herrera NG, Domingos AI, Rastinejad F, et al. DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions. Nature. PMID 26675721 DOI: 10.1038/nature16193  0.96
2015 Wu D, Potluri N, Lu J, Kim Y, Rastinejad F. Structural integration in hypoxia-inducible factors. Nature. 524: 303-8. PMID 26245371 DOI: 10.1038/nature14883  0.96
2015 Rastinejad F, Ollendorff V, Polikarpov I. Response to Moras et al. Trends in Biochemical Sciences. 40: 290-2. PMID 25890866 DOI: 10.1016/j.tibs.2015.03.008  0.96
2015 Santori FR, Huang P, van de Pavert SA, Douglass EF, Leaver DJ, Haubrich BA, Keber R, Lorbek G, Konijn T, Rosales BN, Rozman D, Horvat S, Rahier A, Mebius RE, Rastinejad F, et al. Identification of natural RORγ ligands that regulate the development of lymphoid cells. Cell Metabolism. 21: 286-97. PMID 25651181 DOI: 10.1016/j.cmet.2015.01.004  0.96
2015 Rastinejad F, Ollendorff V, Polikarpov I. Nuclear receptor full-length architectures: confronting myth and illusion with high resolution. Trends in Biochemical Sciences. 40: 16-24. PMID 25435400 DOI: 10.1016/j.tibs.2014.10.011  0.96
2014 Huang P, Chandra V, Rastinejad F. Retinoic acid actions through mammalian nuclear receptors. Chemical Reviews. 114: 233-54. PMID 24308533 DOI: 10.1021/cr400161b  0.96
2013 Rastinejad F, Huang P, Chandra V, Khorasanizadeh S. Understanding nuclear receptor form and function using structural biology. Journal of Molecular Endocrinology. 51: T1-T21. PMID 24103914 DOI: 10.1530/JME-13-0173  0.96
2013 Huh JR, Englund EE, Wang H, Huang R, Huang P, Rastinejad F, Inglese J, Austin CP, Johnson RL, Huang W, Littman DR. Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors. Acs Medicinal Chemistry Letters. 4: 79-84. PMID 24040486 DOI: 10.1021/ml300286h  0.96
2013 Wu D, Potluri N, Kim Y, Rastinejad F. Structure and dimerization properties of the aryl hydrocarbon receptor PAS-A domain. Molecular and Cellular Biology. 33: 4346-56. PMID 24001774 DOI: 10.1128/MCB.00698-13  0.96
2013 Chandra V, Huang P, Potluri N, Wu D, Kim Y, Rastinejad F. Multidomain integration in the structure of the HNF-4α nuclear receptor complex. Nature. 495: 394-8. PMID 23485969 DOI: 10.1038/nature11966  0.96
2011 Huh JR, Leung MW, Huang P, Ryan DA, Krout MR, Malapaka RR, Chow J, Manel N, Ciofani M, Kim SV, Cuesta A, Santori FR, Lafaille JJ, Xu HE, Gin DY, ... Rastinejad F, et al. Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity. Nature. 472: 486-90. PMID 21441909 DOI: 10.1038/nature09978  0.96
2010 Kim D, Blus BJ, Chandra V, Huang P, Rastinejad F, Khorasanizadeh S. Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain. Nature Structural & Molecular Biology. 17: 1027-9. PMID 20657587 DOI: 10.1038/nsmb.1856  0.96
2010 Huang P, Chandra V, Rastinejad F. Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics. Annual Review of Physiology. 72: 247-72. PMID 20148675 DOI: 10.1146/annurev-physiol-021909-135917  0.96
2008 Chandra V, Huang P, Hamuro Y, Raghuram S, Wang Y, Burris TP, Rastinejad F. Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature. 456: 350-6. PMID 19043829 DOI: 10.1038/nature07413  0.96
2007 Raghuram S, Stayrook KR, Huang P, Rogers PM, Nosie AK, McClure DB, Burris LL, Khorasanizadeh S, Burris TP, Rastinejad F. Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta. Nature Structural & Molecular Biology. 14: 1207-13. PMID 18037887 DOI: 10.1038/nsmb1344  0.96
2007 Flanagan JF, Blus BJ, Kim D, Clines KL, Rastinejad F, Khorasanizadeh S. Molecular implications of evolutionary differences in CHD double chromodomains. Journal of Molecular Biology. 369: 334-42. PMID 17433364 DOI: 10.1016/j.jmb.2007.03.024  0.96
2006 DePuy SD, Yao J, Hu C, McIntire W, Bidaud I, Lory P, Rastinejad F, Gonzalez C, Garrison JC, Barrett PQ. The molecular basis for T-type Ca2+ channel inhibition by G protein beta2gamma2 subunits. Proceedings of the National Academy of Sciences of the United States of America. 103: 14590-5. PMID 16973746 DOI: 10.1073/pnas.0603945103  0.96
2005 Flanagan JF, Mi LZ, Chruszcz M, Cymborowski M, Clines KL, Kim Y, Minor W, Rastinejad F, Khorasanizadeh S. Double chromodomains cooperate to recognize the methylated histone H3 tail. Nature. 438: 1181-5. PMID 16372014 DOI: 10.1038/nature04290  0.96
2005 Wright CS, Mi LZ, Lee S, Rastinejad F. Crystal structure analysis of phosphatidylcholine-GM2-activator product complexes: evidence for hydrolase activity. Biochemistry. 44: 13510-21. PMID 16216074 DOI: 10.1021/bi050668w  0.96
2004 Wright CS, Mi LZ, Rastinejad F. Evidence for lipid packaging in the crystal structure of the GM2-activator complex with platelet activating factor. Journal of Molecular Biology. 342: 585-92. PMID 15327957 DOI: 10.1016/j.jmb.2004.07.063  0.96
2004 Ahvazi B, Boeshans KM, Rastinejad F. The emerging structural understanding of transglutaminase 3. Journal of Structural Biology. 147: 200-7. PMID 15193648 DOI: 10.1016/j.jsb.2004.03.009  0.96
2004 Orlowski M, Szyszka M, Kowalska A, Grad I, Zoglowek A, Rymarczyk G, Dobryszycki P, Krowarsch D, Rastinejad F, Kochman M, Ozyhar A. Plasticity of the ecdysone receptor DNA binding domain. Molecular Endocrinology (Baltimore, Md.). 18: 2166-84. PMID 15192079 DOI: 10.1210/me.2004-0154  0.96
2004 Ahvazi B, Boeshans KM, Idler W, Baxa U, Steinert PM, Rastinejad F. Structural basis for the coordinated regulation of transglutaminase 3 by guanine nucleotides and calcium/magnesium. The Journal of Biological Chemistry. 279: 7180-92. PMID 14645372 DOI: 10.1074/jbc.M312310200  0.96
2003 Devarakonda S, Harp JM, Kim Y, Ozyhar A, Rastinejad F. Structure of the heterodimeric ecdysone receptor DNA-binding complex. The Embo Journal. 22: 5827-40. PMID 14592980 DOI: 10.1093/emboj/cdg569  0.96
2003 Elkins PA, Watts JM, Zalacain M, van Thiel A, Vitazka PR, Redlak M, Andraos-Selim C, Rastinejad F, Holmes WM. Insights into catalysis by a knotted TrmD tRNA methyltransferase. Journal of Molecular Biology. 333: 931-49. PMID 14583191 DOI: 10.1016/j.jmb.2003.09.011  0.96
2003 Wright CS, Zhao Q, Rastinejad F. Structural analysis of lipid complexes of GM2-activator protein. Journal of Molecular Biology. 331: 951-64. PMID 12909021 DOI: 10.1016/S0022-2836(03)00794-0  0.96
2003 Mi LZ, Devarakonda S, Harp JM, Han Q, Pellicciari R, Willson TM, Khorasanizadeh S, Rastinejad F. Structural basis for bile acid binding and activation of the nuclear receptor FXR. Molecular Cell. 11: 1093-100. PMID 12718893 DOI: 10.1016/S1097-2765(03)00112-6  0.96
2002 Jacobs SA, Harp JM, Devarakonda S, Kim Y, Rastinejad F, Khorasanizadeh S. The active site of the SET domain is constructed on a knot. Nature Structural Biology. 9: 833-8. PMID 12389038 DOI: 10.1038/nsb861  0.96
2002 Holaska JM, Black BE, Rastinejad F, Paschal BM. Ca2+-dependent nuclear export mediated by calreticulin. Molecular and Cellular Biology. 22: 6286-97. PMID 12167720 DOI: 10.1128/MCB.22.17.6286-6297.2002  0.96
2001 Black BE, Holaska JM, Rastinejad F, Paschal BM. DNA binding domains in diverse nuclear receptors function as nuclear export signals. Current Biology : Cb. 11: 1749-58. PMID 11719216 DOI: 10.1016/S0960-9822(01)00537-1  0.96
2001 Sierk ML, Zhao Q, Rastinejad F. DNA deformability as a recognition feature in the reverb response element. Biochemistry. 40: 12833-43. PMID 11669620 DOI: 10.1021/bi011086r  0.96
2001 Chasse SA, Rastinejad F. Physical structure of nuclear receptor-DNA complexes. Methods in Molecular Biology (Clifton, N.J.). 176: 91-103. PMID 11554341 DOI: 10.1385/1-59259-115-9:91  0.96
2001 Mi LZ, Rastinejad F. Large scale production of nuclear receptor ligand-binding domains. Methods in Molecular Biology (Clifton, N.J.). 176: 81-90. PMID 11554340 DOI: 10.1385/1-59259-115-9:81  0.96
2001 Khorasanizadeh S, Rastinejad F. Nuclear-receptor interactions on DNA-response elements. Trends in Biochemical Sciences. 26: 384-90. PMID 11406412 DOI: 10.1016/S0968-0004(01)01800-X  0.96
2001 Rastinejad F. Retinoid X receptor and its partners in the nuclear receptor family. Current Opinion in Structural Biology. 11: 33-8. PMID 11179889 DOI: 10.1016/S0959-440X(00)00165-2  0.96
2000 Wright CS, Li SC, Rastinejad F. Crystal structure of human GM2-activator protein with a novel beta-cup topology. Journal of Molecular Biology. 304: 411-22. PMID 11090283 DOI: 10.1006/jmbi.2000.4225  0.96
2000 Rastinejad F, Wagner T, Zhao Q, Khorasanizadeh S. Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1. The Embo Journal. 19: 1045-54. PMID 10698945 DOI: 10.1093/emboj/19.5.1045  0.96
2000 Zhao Q, Chasse SA, Devarakonda S, Sierk ML, Ahvazi B, Rastinejad F. Structural basis of RXR-DNA interactions. Journal of Molecular Biology. 296: 509-20. PMID 10669605 DOI: 10.1006/jmbi.1999.3457  0.96
1999 Khorasanizadeh S, Rastinejad F. Transcription factors: the right combination for the DNA lock. Current Biology : Cb. 9: R456-8. PMID 10375516 DOI: 10.1016/S0960-9822(99)80281-4  0.96
1998 Zhao Q, Khorasanizadeh S, Miyoshi Y, Lazar MA, Rastinejad F. Structural elements of an orphan nuclear receptor-DNA complex. Molecular Cell. 1: 849-61. PMID 9660968  0.96
1998 Allison TJ, Wood TC, Briercheck DM, Rastinejad F, Richardson JP, Rule GS. Crystal structure of the RNA-binding domain from transcription termination factor rho. Nature Structural Biology. 5: 352-6. PMID 9586995 DOI: 10.1038/nsb0598-352  0.96
1995 Rastinejad F, Evilia C, Lu P. [23] Studies of nucleic acids and their protein interactions by 19F NMR Methods in Enzymology. 261: 560-575. PMID 8569512 DOI: 10.1016/S0076-6879(95)61025-1  0.96
1995 Rastinejad F, Perlmann T, Evans RM, Sigler PB. Structural determinants of nuclear receptor assembly on DNA direct repeats. Nature. 375: 203-11. PMID 7746322 DOI: 10.1038/375203a0  0.96
1993 Rastinejad F, Artz P, Lu P. Origin of the asymmetrical contact between lac repressor and lac operator DNA Journal of Molecular Biology. 233: 389-399. PMID 8411152 DOI: 10.1006/jmbi.1993.1519  0.96
1993 Rastinejad F, Lu P. Bacteriophage T7 RNA polymerase: 19F-nuclear magnetic resonance observations at 5-Fluorouracil-substituted promoter DNA and RNA transcript Journal of Molecular Biology. 232: 105-122. PMID 8331654  0.96
1990 Mitchell MJ, Hirschowitz W, Rastinejad F, Lu P. Boron trifluoride-methanol complex as a non-depurinating detritylating agent in DNA synthesis. Nucleic Acids Research. 18: 5321. PMID 2205845 DOI: 10.1093/nar/18.17.5321  0.96
1989 Siddiqui SS, Aamodt E, Rastinejad F, Culotti J. Anti-tubulin monoclonal antibodies that bind to specific neurons in Caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 2963-72. PMID 2475594  0.96
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