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Katherine L. Seley-Radtke - Publications

Affiliations: 
Georgia Institute of Technology, Atlanta, GA 
 Chemistry University of Maryland, Baltimore County, Baltimore, MD, United States 
Area:
Organic Chemistry, Biochemistry
Website:
https://chemistry.umbc.edu/faculty/katherine-seley-radtke/
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39/63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Khandazhinskaya A, Eletskaya B, Mironov A, Konstantinova I, Efremenkova O, Andreevskaya S, Smirnova T, Chernousova L, Kondrashova E, Chizhov A, Seley-Radtke K, Kochetkov S, Matyugina E. New Flexible Analogues of 8-Aza-7-deazapurine Nucleosides as Potential Antibacterial Agents. International Journal of Molecular Sciences. 24. PMID 37895100 DOI: 10.3390/ijms242015421  0.328
2023 Khandazhinskaya A, Fateev I, Eletskaya B, Maslova A, Konstantinova I, Seley-Radtke K, Kochetkov S, Matyugina E. Design and Synthesis of New Modified Flexible Purine Bases as Potential Inhibitors of Human PNP. Molecules (Basel, Switzerland). 28. PMID 36770593 DOI: 10.3390/molecules28030928  0.37
2022 Khandazhinskaya A, Fateev I, Konstantinova I, Esipov R, Polyakov K, Seley-Radtke K, Kochetkov S, Matyugina E. Synthesis of New 5'-Norcarbocyclic Aza/Deaza Purine Fleximers - Noncompetitive Inhibitors of Purine Nucleoside Phosphorylase. Frontiers in Chemistry. 10: 867587. PMID 35601551 DOI: 10.3389/fchem.2022.867587  0.384
2021 Khandazhinskaya A, Eletskaya B, Fateev I, Kharitonova M, Konstantinova I, Barai V, Azhayev A, Hyvonen MT, Keinanen TA, Kochetkov S, Seley-Radtke K, Khomutov A, Matyugina E. Novel fleximer pyrazole-containing adenosine analogues: chemical, enzymatic and highly efficient biotechnological synthesis. Organic & Biomolecular Chemistry. PMID 34198312 DOI: 10.1039/d1ob01069g  0.304
2021 Eyer L, Svoboda P, Balvan J, Vičar T, Raudenská M, Štefánik M, Haviernik J, Huvarová I, Straková P, Rudolf I, Hubálek Z, Seley-Radtke K, de Clercq E, Růžek D. Broad-Spectrum Antiviral Activity of 3'-Deoxy-3'-Fluoroadenosine against Emerging Flaviviruses. Antimicrobial Agents and Chemotherapy. 65. PMID 33229424 DOI: 10.1128/AAC.01522-20  0.339
2020 Thames JE, Waters CD, Valle C, Bassetto M, Aouadi W, Martin B, Selisko B, Falat A, Coutard B, Brancale A, Canard B, Decroly E, Seley-Radtke KL. Synthesis and biological evaluation of novel flexible nucleoside analogues that inhibit flavivirus replication in vitro. Bioorganic & Medicinal Chemistry. 28: 115713. PMID 33128910 DOI: 10.1016/J.Bmc.2020.115713  0.312
2020 Vichier-Guerre S, Ku T, Pochet S, Seley-Radtke KL. An expedient synthesis of flexible nucleosides through enzymatic glycosylation of proximal and distal fleximer bases. Chembiochem : a European Journal of Chemical Biology. PMID 31899839 DOI: 10.1002/cbic.201900714  0.347
2019 Khandazhinskaya AL, Matyugina ES, Solyev PN, Wilkinson M, Buckheit KW, Buckheit RW, Chernousova LN, Smirnova TG, Andreevskaya SN, Alzahrani KJ, Natto MJ, Kochetkov SN, de Koning HP, Seley-Radtke KL. Investigation of 5'-Norcarbocyclic Nucleoside Analogues as Antiprotozoal and Antibacterial Agents. Molecules (Basel, Switzerland). 24. PMID 31546633 DOI: 10.3390/Molecules24193433  0.319
2019 Cawrse BM, Robinson NM, Lee NC, Wilson GM, Seley-Radtke KL. Structural and Biological Investigations for a Series of N-5 Substituted Pyrrolo[3,2-]pyrimidines as Potential Anti-Cancer Therapeutics. Molecules (Basel, Switzerland). 24. PMID 31340431 DOI: 10.3390/Molecules24142656  0.323
2018 Temburnikar K, Seley-Radtke KL. Recent advances in synthetic approaches for medicinal chemistry of C-nucleosides. Beilstein Journal of Organic Chemistry. 14: 772-785. PMID 29719574 DOI: 10.3762/Bjoc.14.65  0.775
2017 Cawrse BM, Lapidus RS, Cooper B, Choi EY, Seley-Radtke KL. Anticancer Properties of Halogenated Pyrrolo[3,2-d]pyrimidines with Decreased Toxicity via N5 Substitution. Chemmedchem. PMID 29193845 DOI: 10.1002/cmdc.201700641  0.308
2017 Alzahrani KJ, Matyugina ES, Khandazhinskaya AL, Kochetkov SN, Seley-Radtke KL, Koning HP. Evaluation of the antiprotozoan properties of 5'-norcarbocyclic pyrimidine nucleosides. Bioorganic & Medicinal Chemistry Letters. PMID 28571825 DOI: 10.1016/J.Bmcl.2017.05.052  0.339
2015 Babkov DA, Khandazhinskaya AL, Chizhov AO, Andrei G, Snoeck R, Seley-Radtke KL, Novikov MS. Toward the discovery of dual HCMV-VZV inhibitors: Synthesis, structure activity relationship analysis, and cytotoxicity studies of long chained 2-uracil-3-yl-N-(4-phenoxyphenyl)acetamides. Bioorganic & Medicinal Chemistry. 23: 7035-44. PMID 26443550 DOI: 10.1016/J.Bmc.2015.09.033  0.333
2015 Fateev IV, Kharitonova MI, Antonov KV, Konstantinova ID, Stepanenko VN, Esipov RS, Seela F, Temburnikar KW, Seley-Radtke KL, Stepchenko VA, Sokolov YA, Miroshnikov AI, Mikhailopulo IA. Recognition of Artificial Nucleobases by E. coli Purine Nucleoside Phosphorylase versus its Ser90Ala Mutant in the Synthesis of Base-Modified Nucleosides. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 13401-19. PMID 26230190 DOI: 10.1002/Chem.201501334  0.773
2015 Temburnikar KW, Ross CR, Wilson GM, Balzarini J, Cawrse BM, Seley-Radtke KL. Antiproliferative activities of halogenated pyrrolo[3,2-d]pyrimidines. Bioorganic & Medicinal Chemistry. PMID 26122770 DOI: 10.1016/j.bmc.2015.06.025  0.762
2015 Peters HL, Jochmans D, de Wilde AH, Posthuma CC, Snijder EJ, Neyts J, Seley-Radtke KL. Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity. Bioorganic & Medicinal Chemistry Letters. 25: 2923-6. PMID 26048809 DOI: 10.1016/J.Bmcl.2015.05.039  0.366
2015 Ross CR, Temburnikar KW, Wilson GM, Seley-Radtke KL. Mitotic arrest of breast cancer MDA-MB-231 cells by a halogenated thieno[3,2-d]pyrimidine. Bioorganic & Medicinal Chemistry Letters. 25: 1715-7. PMID 25791452 DOI: 10.1016/J.Bmcl.2015.02.071  0.738
2015 Babkov DA, Valuev-Elliston VT, Paramonova MP, Ozerov AA, Ivanov AV, Chizhov AO, Khandazhinskaya AL, Kochetkov SN, Balzarini J, Daelemans D, Pannecouque C, Seley-Radtke KL, Novikov MS. Scaffold hopping: exploration of acetanilide-containing uracil analogues as potential NNRTIs. Bioorganic & Medicinal Chemistry. 23: 1069-81. PMID 25638501 DOI: 10.1016/J.Bmc.2015.01.002  0.369
2014 Zimmermann SC, O'Neill E, Ebiloma GU, Wallace LJ, De Koning HP, Seley-Radtke KL. Design and synthesis of a series of truncated neplanocin fleximers. Molecules (Basel, Switzerland). 19: 21200-14. PMID 25521119 DOI: 10.3390/Molecules191221200  0.349
2014 Temburnikar KW, Zimmermann SC, Kim NT, Ross CR, Gelbmann C, Salomon CE, Wilson GM, Balzarini J, Seley-Radtke KL. Antiproliferative activities of halogenated thieno[3,2-d]pyrimidines. Bioorganic & Medicinal Chemistry. 22: 2113-22. PMID 24631358 DOI: 10.1016/J.Bmc.2014.02.033  0.778
2013 Novikov MS, Babkov DA, Paramonova MP, Chizhov AO, Khandazhinskaya AL, Seley-Radtke KL. A highly facile approach to the synthesis of novel 2-(3-benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-N-phenylacetamides. Tetrahedron Letters. 54: 576-578. PMID 32287444 DOI: 10.1016/J.Tetlet.2012.11.090  0.322
2013 Temburnikar K, Brace K, Seley-Radtke KL. Synthesis of 2'-deoxy-9-deaza nucleosides using Heck methodology. The Journal of Organic Chemistry. 78: 7305-11. PMID 23806030 DOI: 10.1021/Jo400913K  0.76
2013 Novikov MS, Babkov DA, Paramonova MP, Khandazhinskaya AL, Ozerov AA, Chizhov AO, Andrei G, Snoeck R, Balzarini J, Seley-Radtke KL. Synthesis and anti-HCMV activity of 1-[ω-(phenoxy)alkyl]uracil derivatives and analogues thereof. Bioorganic & Medicinal Chemistry. 21: 4151-7. PMID 23743443 DOI: 10.1016/J.Bmc.2013.05.009  0.332
2013 Zimmermann SC, Sadler JM, O'Daniel PI, Kim NT, Seley-Radtke KL. "Reverse" carbocyclic fleximers: synthesis of a new class of adenosine deaminase inhibitors. Nucleosides, Nucleotides & Nucleic Acids. 32: 137-54. PMID 23473101 DOI: 10.1080/15257770.2013.771187  0.776
2012 Wauchope OR, Velasquez M, Seley-Radtke K. Synthetic Routes to a Series of Proximal and Distal 2'-Deoxy Fleximers. Synthesis. 44: 3496-3504. PMID 24465059 DOI: 10.1055/S-0032-1316791  0.769
2012 Wauchope OR, Johnson C, Krishnamoorthy P, Andrei G, Snoeck R, Balzarini J, Seley-Radtke KL. Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues. Bioorganic & Medicinal Chemistry. 20: 3009-15. PMID 22464686 DOI: 10.1016/J.Bmc.2012.03.004  0.78
2012 Temburnikar K, Zhang Z, Seley-Radtke K. Modified synthesis of 3'-O-TBDPS-protected furanoid glycal. Nucleosides, Nucleotides & Nucleic Acids. 31: 319-27. PMID 22444193 DOI: 10.1080/15257770.2012.656212  0.746
2011 Zimmermann SC, Sadler JM, Andrei G, Snoeck R, Balzarini J, Seley-Radtke KL. Carbocyclic 5'-nor "reverse" fleximers. Design, synthesis, and preliminary biological activity. Medchemcomm. 2. PMID 24312722 DOI: 10.1039/C1Md00094B  0.742
2011 Manvilla BA, Wauchope O, Seley-Radtke KL, Drohat AC. NMR studies reveal an unexpected binding site for a redox inhibitor of AP endonuclease 1. Biochemistry. 50: 10540-9. PMID 22032234 DOI: 10.1021/Bi201071G  0.74
2011 Novikov MS, Ivanova ON, Ivanov AV, Ozerov AA, Valuev-Elliston VT, Temburnikar K, Gurskaya GV, Kochetkov SN, Pannecouque C, Balzarini J, Seley-Radtke KL. 1-[2-(2-Benzoyl- and 2-benzylphenoxy)ethyl]uracils as potent anti-HIV-1 agents. Bioorganic & Medicinal Chemistry. 19: 5794-802. PMID 21903401 DOI: 10.1016/J.Bmc.2011.08.025  0.772
2010 Novikov MS, Buckheit RW, Temburnikar K, Khandazhinskaya AL, Ivanov AV, Seley-Radtke KL. 1-Benzyl derivatives of 5-(arylamino)uracils as anti-HIV-1 and anti-EBV agents. Bioorganic & Medicinal Chemistry. 18: 8310-4. PMID 21035347 DOI: 10.1016/J.Bmc.2010.09.070  0.789
2010 Wauchope OR, Tomney MJ, Pepper JL, Korba BE, Seley-Radtke KL. Tricyclic 2'-C-modified nucleosides as potential anti-HCV therapeutics. Organic Letters. 12: 4466-9. PMID 20845910 DOI: 10.1021/Ol101482H  0.744
2009 Seley-Radtke KL, Sunkara NK. Carbocyclic thymidine analogues for use as potential therapeutic agents. Nucleosides, Nucleotides & Nucleic Acids. 28: 633-41. PMID 20183606 DOI: 10.1080/15257770903091920  0.766
2009 Sadler JM, Mosley SL, Dorgan KM, Zhou ZS, Seley-Radtke KL. Synthetic strategies toward carbocyclic purine-pyrimidine hybrid nucleosides. Bioorganic & Medicinal Chemistry. 17: 5520-5. PMID 19592260 DOI: 10.1016/J.Bmc.2009.06.039  0.728
2008 Zhang Z, Wauchope OR, Seley-Radtke KL. Mechanistic studies in the synthesis of a series of thieno-expanded xanthosine and guanosine nucleosides. Tetrahedron. 64: 10791-10797. PMID 19946353 DOI: 10.1016/j.tet.2008.09.011  0.744
2008 O'Daniel PI, Jefferson M, Wiest O, Seley-Radtke KL. A computational study of expanded heterocyclic nucleosides in DNA. Journal of Biomolecular Structure & Dynamics. 26: 283-92. PMID 18808194 DOI: 10.1080/07391102.2008.10507243  0.755
2008 Seley-Radtke KL, Zhang Z, Wauchope OR, Zimmermann SC, Ivanov A, Korba B. Hetero-expanded purine nucleosides. Design, synthesis and preliminary biological activity. Nucleic Acids Symposium Series (2004). 635-6. PMID 18776540 DOI: 10.1093/nass/nrn321  0.785
2008 Sadler JM, Ojewoye O, Seley-Radtke KL. "Reverse fleximers": introduction of a series of 5-substituted carbocyclic uridine analogues. Nucleic Acids Symposium Series (2004). 571-2. PMID 18776508 DOI: 10.1093/nass/nrn289  0.704
2006 Mosley SL, Bakke BA, Sadler JM, Sunkara NK, Dorgan KM, Zhou ZS, Seley-Radtke KL. Carbocyclic pyrimidine nucleosides as inhibitors of S-adenosylhomocysteine hydrolase. Bioorganic & Medicinal Chemistry. 14: 7967-71. PMID 16904326 DOI: 10.1016/J.Bmc.2006.07.052  0.752
Low-probability matches (unlikely to be authored by this person)
2015 Chen Z, Jochmans D, Ku T, Paeshuyse J, Neyts J, Seley-Radtke KL. Bicyclic and Tricyclic "Expanded" Nucleobase Analogues of Sofosbuvir: New Scaffolds for Hepatitis C Therapies. Acs Infectious Diseases. 1: 357-66. PMID 27624884 DOI: 10.1021/Acsinfecdis.5B00029  0.298
2019 Yates MK, Chatterjee P, Flint M, Arefeayne Y, Makuc D, Plavec J, Spiropoulou CF, Seley-Radtke KL. Probing the Effects of Pyrimidine Functional Group Switches on Acyclic Fleximer Analogues for Antiviral Activity. Molecules (Basel, Switzerland). 24. PMID 31480658 DOI: 10.3390/Molecules24173184  0.295
2015 Chen Z, Ku TC, Seley-Radtke KL. Thiophene-expanded guanosine analogues of Gemcitabine. Bioorganic & Medicinal Chemistry Letters. 25: 4274-6. PMID 26316465 DOI: 10.1016/J.Bmcl.2015.07.086  0.292
2019 Yates MK, Seley-Radtke KL. The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold. Antiviral Research. 162: 5-21. PMID 30529089 DOI: 10.1016/J.Antiviral.2018.11.016  0.285
2019 Seley-Radtke K, Deval J. Advances in antiviral nucleoside analogues and their prodrugs. Antiviral Chemistry & Chemotherapy. 26: 2040206618781410. PMID 29890841 DOI: 10.1177/2040206618781410  0.269
2016 Geisman AN, Valuev-Elliston VT, Ozerov AA, Khandazhinskaya AL, Chizhov AO, Kochetkov SN, Pannecouque C, Naesens L, Seley-Radtke KL, Novikov MS. 1,6-Bis[(benzyloxy)methyl]uracil derivatives-Novel antivirals with activity against HIV-1 and influenza H1N1 virus. Bioorganic & Medicinal Chemistry. PMID 27112451 DOI: 10.1016/J.Bmc.2016.04.010  0.267
2013 Novikov MS, Valuev-Elliston VT, Babkov DA, Paramonova MP, Ivanov AV, Gavryushov SA, Khandazhinskaya AL, Kochetkov SN, Pannecouque C, Andrei G, Snoeck R, Balzarini J, Seley-Radtke KL. N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase. Bioorganic & Medicinal Chemistry. 21: 1150-8. PMID 23357038 DOI: 10.1016/J.Bmc.2012.12.027  0.266
2020 Seley-Radtke K. Discovery, Design, Synthesis, and Application of Nucleoside/Nucleotides. Molecules (Basel, Switzerland). 25. PMID 32230805 DOI: 10.3390/Molecules25071526  0.257
2022 Thames JE, Seley-Radtke KL. Comparison of the Old and New - Novel Mechanisms of Action for Anti-coronavirus Nucleoside Analogues. Chimia. 76: 409-417. PMID 38069712 DOI: 10.2533/chimia.2022.409  0.256
2017 Yates MK, Raje MR, Chatterjee P, Spiropoulou CF, Bavari S, Flint M, Soloveva V, Seley-Radtke KL. Flex-nucleoside analogues - Novel therapeutics against filoviruses. Bioorganic & Medicinal Chemistry Letters. PMID 28465098 DOI: 10.1016/J.Bmcl.2017.04.069  0.252
2019 Eyer L, Nencka R, de Clercq E, Seley-Radtke K, Růžek D. Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses. Antiviral Chemistry & Chemotherapy. 26: 2040206618761299. PMID 29534608 DOI: 10.1177/2040206618761299  0.249
2018 Seley-Radtke KL, Yates MK. The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold. Antiviral Research. 154: 66-86. PMID 29649496 DOI: 10.1016/J.Antiviral.2018.04.004  0.248
2019 Ku T, Lopresti N, Shirley M, Mori M, Marchant J, Heng X, Botta M, Summers MF, Seley-Radtke KL. Synthesis of distal and proximal fleximer base analogues and evaluation in the nucleocapsid protein of HIV-1. Bioorganic & Medicinal Chemistry. PMID 31126822 DOI: 10.1016/J.Bmc.2019.05.019  0.237
2019 Seley-Radtke K. Flexibility-Not just for yoga anymore! Antiviral Chemistry & Chemotherapy. 26: 2040206618756788. PMID 29466861 DOI: 10.1177/2040206618756788  0.226
2015 Matyugina E, Novikov M, Babkov D, Ozerov A, Chernousova L, Andreevskaya S, Smirnova T, Karpenko I, Chizhov A, Murthu P, Lutz S, Kochetkov S, Seley-Radtke KL, Khandazhinskaya AL. 5-Arylaminouracil Derivatives: New Inhibitors of Mycobacterium tuberculosis. Chemical Biology & Drug Design. PMID 26061192 DOI: 10.1111/Cbdd.12603  0.206
2018 Khandazhinskaya AL, Alexandrova LA, Matyugina ES, Solyev PN, Efremenkova OV, Buckheit KW, Wilkinson M, Buckheit RW, Chernousova LN, Smirnova TG, Andreevskaya SN, Leonova OG, Popenko VI, Kochetkov SN, Seley-Radtke KL. Novel 5'-Norcarbocyclic Pyrimidine Derivatives as Antibacterial Agents. Molecules (Basel, Switzerland). 23. PMID 30477147 DOI: 10.3390/molecules23123069  0.194
2021 Seley-Radtke KL, Thames JE, Waters CD. Broad spectrum antiviral nucleosides-Our best hope for the future. Annual Reports in Medicinal Chemistry. 57: 109-132. PMID 34728865 DOI: 10.1016/bs.armc.2021.09.001  0.146
2022 Eyer L, Seley-Radtke K, Ruzek D. New directions in the experimental therapy of tick-borne encephalitis. Antiviral Research. 105504. PMID 36574904 DOI: 10.1016/j.antiviral.2022.105504  0.133
2006 Quirk S, Seley-Radtke KL. Purification, crystallization and preliminary X-ray characterization of the human GTP fucose pyrophosphorylase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 392-4. PMID 16582493 DOI: 10.1107/S1744309106008529  0.124
2019 Tramontano E, Tarbet B, Spengler JR, Seley-Radtke K, Meier C, Jordan R, Janeba Z, Gowen B, Gentry B, Esté JA, Bray M, Andrei G, Schang LM. Meeting report: 32nd International Conference on Antiviral Research. Antiviral Research. 104550. PMID 31302149 DOI: 10.1016/J.Antiviral.2019.104550  0.102
2022 Spengler JR, Welch SR, Deval J, Gentry BG, Brancale A, Carter K, Moffat J, Meier C, Seley-Radtke KL, Schang LM. Meeting report: 35th international conference on antiviral research in Seattle, WA, USA - March 21-25, 2022. Antiviral Research. 105521. PMID 36596323 DOI: 10.1016/j.antiviral.2022.105521  0.095
2023 Spengler JR, Carter K, Delang L, Durantel D, Gowen BB, Herrero LJ, Hurst B, Janeba Z, Jordan R, Luo D, Meier C, Moffat J, Rocha-Pereira J, Seley-Radtke KL, Welch SR, et al. Meeting report: 36th international conference on antiviral research in Lyon, France, March 13-17, 2023. Antiviral Research. 105678. PMID 37494979 DOI: 10.1016/j.antiviral.2023.105678  0.094
2022 Brancale A, Carter K, Delang L, Deval J, Durantel D, Gentry BG, Jordan R, Julander JG, Lo MK, Pérez-Pérez MJ, Schang LM, Seley-Radtke KL, Shi PY, Vasudevan SG, Whitley RJ, et al. Meeting report: 34th international conference on antiviral research. Antiviral Chemistry & Chemotherapy. 30: 20402066221130853. PMID 36305015 DOI: 10.1177/20402066221130853  0.086
2021 Seley-Radtke K. Small molecule antivirals - Still our best hope for a cure. Antiviral Chemistry & Chemotherapy. 28: 2040206620963964. PMID 33153278 DOI: 10.1177/2040206620963964  0.072
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