Gerald L. Mechanic - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Biochemistry

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
1992 Otsubo K, Katz EP, Mechanic GL, Yamauchi M. Cross-linking connectivity in bone collagen fibrils: the COOH-terminal locus of free aldehyde. Biochemistry. 31: 396-402. PMID 1731897 DOI: 10.1021/Bi00117A013  0.499
1991 Woodley DT, Yamauchi M, Wynn KC, Mechanic G, Briggaman RA. Collagen telopeptides (cross-linking sites) play a role in collagen gel lattice contraction. The Journal of Investigative Dermatology. 97: 580-5. PMID 1875057 DOI: 10.1111/1523-1747.Ep12481920  0.449
1990 Mechanic GL, Arnaud SB, Boyde A, Bromage TG, Buckendahl P, Elliott JC, Katz EP, Durnova GN. Regional distribution of mineral and matrix in the femurs of rats flown on Cosmos 1887 biosatellite. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 34-40. PMID 2295376 DOI: 10.1096/Fasebj.4.1.2295376  0.402
1990 Tsuzaki M, Yamauchi M, Mechanic GL. Bovine dental pulp collagens: characterization of types III and V collagen. Archives of Oral Biology. 35: 195-200. PMID 2112377 DOI: 10.1016/0003-9969(90)90055-F  0.325
1990 Ono S, Mechanic GL, Yamauchi M. Amyotrophic lateral sclerosis: unusually low content of collagen in skin. Journal of the Neurological Sciences. 100: 234-7. PMID 2089137 DOI: 10.1016/0022-510X(90)90038-O  0.314
1989 Yamauchi M, Katz EP, Otsubo K, Teraoka K, Mechanic GL. Cross-linking and stereospecific structure of collagen in mineralized and nonmineralized skeletal tissues. Connective Tissue Research. 21: 159-67; discussion 1. PMID 2605940 DOI: 10.3109/03008208909050006  0.469
1989 Katz EP, Wachtel E, Yamauchi M, Mechanic GL. The structure of mineralized collagen fibrils. Connective Tissue Research. 21: 149-54; discussion 1. PMID 2605938 DOI: 10.3109/03008208909050005  0.377
1989 Graham L, Mechanic GL. Simultaneous determination of the reducible and nonreducible cross-links of connective tissue. Analysis of mineralized and nonmineralized bone collagen. Biochemistry. 28: 7889-95. PMID 2514795 DOI: 10.1021/Bi00445A051  0.648
1988 Yamauchi M, Young DR, Chandler GS, Mechanic GL. Cross-linking and new bone collagen synthesis in immobilized and recovering primate osteoporosis. Bone. 9: 415-8. PMID 3150289 DOI: 10.1016/8756-3282(88)90124-X  0.471
1988 Yamauchi M, Woodley DT, Mechanic GL. Aging and cross-linking of skin collagen. Biochemical and Biophysical Research Communications. 152: 898-903. PMID 3130057 DOI: 10.1016/S0006-291X(88)80124-4  0.433
1987 Mechanic GL, Katz EP, Henmi M, Noyes C, Yamauchi M. Locus of a histidine-based, stable trifunctional, helix to helix collagen cross-link: stereospecific collagen structure of type I skin fibrils. Biochemistry. 26: 3500-9. PMID 3651393 DOI: 10.1021/Bi00386A038  0.429
1987 Yamauchi M, London RE, Guenat C, Hashimoto F, Mechanic GL. Structure and formation of a stable histidine-based trifunctional cross-link in skin collagen. The Journal of Biological Chemistry. 262: 11428-34. PMID 3624221  0.311
1987 Mechanic GL, Farb RM, Henmi M, Ranga V, Bromberg PA, Yamauchi M. Structural crosslinking of lung connective tissue collagen in the blotchy mouse. Experimental Lung Research. 12: 109-17. PMID 3569165 DOI: 10.3109/01902148709062835  0.367
1986 Yamauchi M, Katz EP, Mechanic GL. Intermolecular cross-linking and stereospecific molecular packing in type I collagen fibrils of the periodontal ligament. Biochemistry. 25: 4907-13. PMID 3768322 DOI: 10.1021/Bi00365A027  0.378
1986 Mechanic GL, Young DR, Banes AJ, Yamauchi M. Nonmineralized and mineralized bone collagen in bone of immobilized monkeys. Calcified Tissue International. 39: 63-8. PMID 3091222 DOI: 10.1007/Bf02553292  0.377
1986 Graham L, Mechanic GL. [14C]acrylonitrile: preparation via a stable tosylate intermediate and quantitative reaction with amine residues in collagen. Analytical Biochemistry. 153: 354-8. PMID 3085538 DOI: 10.1016/0003-2697(86)90103-X  0.557
1986 Yamauchi M, Kuboki Y, Sasaki S, Mechanic GL. New pepsin-solubilized low molecular weight collagenous component possibly unique to periodontal ligament. Biochemistry. 25: 1997-2002. PMID 3011074 DOI: 10.1021/Bi00356A024  0.409
1986 Yamauchi M, Mechanic GL. Collagen crosslinks in soft and hard tissues, structural control of mineralization Bone. 7: 401. DOI: 10.1016/8756-3282(86)90306-6  0.367
1983 Banes AJ, Yamauchi M, Mechanic GL. Nonmineralized and mineralized compartments of bone: the role of pyridinoline in nonmineralized collagen. Biochemical and Biophysical Research Communications. 113: 975-81. PMID 6870905 DOI: 10.1016/0006-291X(83)91094-X  0.474
1982 Yamauchi M, Noyes C, Kuboki Y, Mechanic GL. Collagen structural microheterogeneity and a possible role for glycosylated hydroxylysine in type I collagen. Proceedings of the National Academy of Sciences of the United States of America. 79: 7684-8. PMID 6961443 DOI: 10.1073/Pnas.79.24.7684  0.401
1982 Kuboki Y, Mechanic GL. Comparative molecular distribution of cross-link in bone and dentin collagen. Structure-function relationships. Calcified Tissue International. 34: 306-8. PMID 6809294 DOI: 10.1007/Bf02411256  0.495
1981 Yamauchi M, Banes AJ, Kuboki Y, Mechanic GL. A comparative study of the distribution of the stable crosslink, pyridinoline, in bone collagens from normal, osteoblastoma, and vitamin D-deficient chicks. Biochemical and Biophysical Research Communications. 102: 59-65. PMID 7306173 DOI: 10.1016/0006-291X(81)91488-1  0.41
1981 Kuboki Y, Tsuzaki M, Sasaki S, Liu CF, Mechanic GL. Location of the intermolecular cross-links in bovine dentin collagen, solubilization with trypsin and isolation of cross-link peptides containing dihydroxylysinonorleucine and pyridinoline. Biochemical and Biophysical Research Communications. 102: 119-26. PMID 7306142 DOI: 10.1016/0006-291X(81)91497-2  0.379
1981 Kuboki Y, Takagi T, Sasaki S, Saito S, Mechanic GL. Comparative collagen biochemistry of bovine periodontium, gingiva, and dental pulp. Journal of Dental Research. 60: 159-63. PMID 6936457 DOI: 10.1177/00220345810600021201  0.488
1981 Kuboki Y, Takagi T, Shimokawa H, Oguchi H, Sasaki S, Mechanic GL. Location of an intermolecular crosslink in bovine bone collagen. Connective Tissue Research. 9: 107-14. PMID 6458447 DOI: 10.3109/03008208109160248  0.422
1980 Fukae M, Mechanic GL. Maturation of collagenous tissue. Temporal sequence of formation of peptidyl lysine-derived cross-linking aldehydes and cross-links in collagen. The Journal of Biological Chemistry. 255: 6511-8. PMID 6771270  0.33
1980 Amiel D, Akeson WH, Harwood FL, Mechanic GL. The effect of immobilization on the types of collagen synthesized in periarticular connective tissue. Connective Tissue Research. 8: 27-32. PMID 6450661 DOI: 10.3109/03008208009152118  0.392
1979 Banes AJ, Nebes S, Smith RE, Mechanic GL. DMSO normalizes collagen synthesis in MAV-2(O)-infected chick embryo cells. General Pharmacology. 10: 521-3. PMID 520806 DOI: 10.1016/0306-3623(79)90018-1  0.31
1978 Banes AJ, Bernstein PH, Smith RE, Mechanic GL. Collagen biochemistry of osteopetrotic bone: I. Quantitative changes in bone collagen cross-links in virus-induced avian osteopetrosis. Biochemical and Biophysical Research Communications. 81: 1390-7. PMID 666824 DOI: 10.1016/0006-291X(78)91290-1  0.449
1978 Banes AJ, Smith RE, Mechanic GL. Increased collagen synthesis in myeloblastosis-associated virus-infected chicken embryo fibroblasts. Biochemical and Biophysical Research Communications. 82: 723-6. PMID 208575 DOI: 10.1016/0006-291X(78)90934-8  0.317
1978 Boyde A, Banes AJ, Dillaman RM, Mechanic GL. A morphological study of an avian bone disorder caused by myetosis-associated virus Metabolic Bone Disease and Related Research. 1: 235-242. DOI: 10.1016/0221-8747(78)90008-5  0.386
1977 Amiel D, Akeson WH, Harwood FL, Schmidt DA, Mechanic GL. Effect of low dosage schedule of D-penicillamine on collagen cross-linking in a nine week immobilized rabbit knee. Connective Tissue Research. 5: 179-83. PMID 144582 DOI: 10.3109/03008207709152269  0.398
1977 Akeson WH, Amiel D, Mechanic GL, Woo SL, Harwood FL, Hamer ML. Collagen cross-linking alterations in joint contractures: changes in the reducible cross-links in periarticular connective tissue collagen after nine weeks of immobilization. Connective Tissue Research. 5: 15-9. PMID 141358 DOI: 10.3109/03008207709152607  0.425
1977 Mechanic GL. The qualitative and quantitative crosslink chemistry of collagen matrices. Advances in Experimental Medicine and Biology. 86: 699-708. PMID 20755 DOI: 10.1007/978-1-4757-9113-6_38  0.445
1976 Fukae M, Mechanic GL. Maturation of collagenous tissue: specific in vivo proteolytic cleavage of only alpha1(I) chains. Biochemical and Biophysical Research Communications. 71: 651-7. PMID 962944 DOI: 10.1016/0006-291X(76)90837-8  0.404
1976 Mechanic GL. Maturation of chick bone collagen and quantification of its structural crosslinks: vitamin D status and cohesiveness of the collagen macromolecular matrix. Calcified Tissue Research. 21: 177-84. PMID 953805 DOI: 10.1007/Bf02546448  0.353
1975 Fukae M, Mechanic GL. Chromatographically different type II collagens from human normal and osteoarthritic cartilage. Biochemical and Biophysical Research Communications. 67: 1575-80. PMID 1201103 DOI: 10.1016/0006-291X(75)90206-5  0.375
1975 Russell JE, Avioli LV, Mechanic G. The nature of the collagen cross links in bone in the chronic uraemic state Biochemical Journal. 145: 119-120. PMID 1191249 DOI: 10.1042/bj1450119  0.328
1975 Mechanic GL, Toverud SU, Ramp WK, Gonnerman WA. The effect of vitamin D on the structural crosslinks and maturation of chick bone collagen. Biochimica Et Biophysica Acta. 393: 419-25. PMID 1148223 DOI: 10.1016/0005-2795(75)90070-7  0.325
1974 Mechanic GL. Collagen crosslinks: direct evidence of a reducible stable form of the Schiff base delta-6 dehydro-5,5-dihydroxylysinonorleucine as 5-keto-5'hydroxylysinonorleucine in bone collagen. Biochemical and Biophysical Research Communications. 56: 923-7. PMID 4857010 DOI: 10.1016/S0006-291X(74)80276-7  0.448
1974 Mechanic GL, Kuboki Y, Shimokawa H, Nakamoto K, Sasaki S, Kawanishi Y. Collagen crosslinks: direct quantitative determination of stable structural crosslinks in bone and dentin collagens. Biochemical and Biophysical Research Communications. 60: 756-63. PMID 4472502 DOI: 10.1016/0006-291X(74)90305-2  0.465
1974 Mechanic GL. An automated scintillation counting system with high efficiency for continuous analysis: cross-links of (3H) NaBH4-reduced collagen. Analytical Biochemistry. 61: 349-54. PMID 4425294 DOI: 10.1016/0003-2697(74)90401-1  0.346
1974 Mechanic GL. A two column system for complete resolution of NaBH4-reduced cross-links from collagen. Analytical Biochemistry. 61: 355-61. PMID 4422653 DOI: 10.1016/0003-2697(74)90402-3  0.405
1974 Kuboki Y, Mechanic GL. The distribution of delta, delta'-dihydroxylysinonorleucine in bovine tendon and dentin. Connective Tissue Research. 2: 223-30. PMID 4279802 DOI: 10.3109/03008207409152247  0.383
1974 Jackson D, Mechanic G. Cross-link patterns of collagens synthesised by cultures of 3T6 and 3T3 fibroblasts and by fibroblasts of various granulation tissues Biochimica Et Biophysica Acta (Bba) - Protein Structure. 336: 228-233. DOI: 10.1016/0005-2795(74)90400-0  0.368
1974 Jackson D, Ayad S, Mechanic G. Effect of heat on some collagen cross-links Biochimica Et Biophysica Acta (Bba) - Protein Structure. 336: 100-107. DOI: 10.1016/0005-2795(74)90388-2  0.386
1973 Kuboki Y, Tanzer ML, Mechanic GL. Isolation of polypeptides containing the intermolecular cross-link , '-dihydroxylysinonorleucine from dentin collagen. Archives of Biochemistry and Biophysics. 158: 106-15. PMID 4354028 DOI: 10.1016/0003-9861(73)90602-4  0.418
1972 Mechanic G, Gallop PM, Tanzer ML. The nature of crosslinking in collagens from mineralized tissues. Biochemical and Biophysical Research Communications. 45: 644-53. PMID 5128174 DOI: 10.1016/0006-291X(71)90465-7  0.488
1972 Mechanic G. Crosslinking of collagen in a heritable disorder of connective tissue: Ehlers-Danlos syndrome. Biochemical and Biophysical Research Communications. 47: 267-72. PMID 5027136 DOI: 10.1016/S0006-291X(72)80038-X  0.345
1972 Mechanic GL, Toverud SU, Ramp WK. Quantitative changes of bone collagen crosslinks and precursors in vitamin D deficiency. Biochemical and Biophysical Research Communications. 47: 760-5. PMID 5026293 DOI: 10.1016/0006-291X(72)90557-8  0.374
1972 Forrest L, Shuttleworth A, Jackson DS, Mechanic GL. A comparison between the reducible intermolecular crosslinks of the collagens from mature dermis and young dermal scar tissue of the guinea pig. Biochemical and Biophysical Research Communications. 46: 1776-81. PMID 5015228 DOI: 10.1016/0006-291X(72)90050-2  0.443
1971 Mechanic GL. The intermolecular cross-link precursors in collagens as related to function. Identification of -hydroxy -amino adipic semialdehyde in tendon collagen. Israel Journal of Medical Sciences. 7: 458-62. PMID 5567515  0.337
1971 Mechanic G, Tanzer ML. Biochemistry of collagen crosslinking. Isolation of a new crosslink, hydroxylysinohydroxynorleucine, and its reduced precursor, dihydroxynorleucine, from bovine tendon. Biochemical and Biophysical Research Communications. 41: 1597-604. PMID 5530628 DOI: 10.1016/0006-291X(70)90571-1  0.385
1971 De Luque O, Mechanic G, Tanzer ML. Isolation of peptides containing the cross-link, hydroxylysinonorleucine, from reconstituted collagen fibrils. Biochemistry. 9: 4987-93. PMID 4320362 DOI: 10.1021/Bi00827A024  0.393
1970 Tanzer ML, Mechanic G, Gallop PM. Isolation of hydroxylsinonorleucine and its lactone from reconstituted collagen fibrils. Biochimica Et Biophysica Acta. 207: 548-52. PMID 5452678 DOI: 10.1016/S0005-2795(70)80017-4  0.302
1970 Tanzer ML, Mechanic G. Isolation of lysinonorleucine from collagen. Biochemical and Biophysical Research Communications. 39: 183-9. PMID 5438294 DOI: 10.1016/0006-291X(70)90775-8  0.447
1968 Tanzer ML, Mechanic G. Collagen reduction by sodium borohydride: Effects of reconstitution, maturation and lathyrism Biochemical and Biophysical Research Communications. 32: 885-892. PMID 5682312 DOI: 10.1016/0006-291X(68)90324-0  0.367
1967 Glimcher MJ, Levine PT, Mechanic GL. Studies on the source of hydroxyproline in bovine enamel. Biochimica Et Biophysica Acta. 136: 36-44. PMID 6032047 DOI: 10.1016/0304-4165(67)90318-2  0.407
1965 STERN BD, GLIMCHER MJ, MECHANIC GL, GOLDHABER P. STUDIES OF COLLAGEN DEGRADATION DURING BONE RESORPTION IN TISSUE CULTURE. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 119: 577-83. PMID 14328949 DOI: 10.3181/00379727-119-30243  0.437
1965 Kaufman EJ, Glimcher MJ, Mechanic GL, Goldhaber P. Collagenolytic activity during active bone resorption in tissue culture. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 120: 632-7. PMID 5858686 DOI: 10.3181/00379727-120-30611  0.41
1965 Bonar LC, Glimcher MJ, Mechanic GL. The molecular structure of the neutral-soluble proteins of embryonic bovine enamel in the solid state. Journal of Ultrastructure Research. 13: 308-17. PMID 5320629 DOI: 10.1016/S0022-5320(65)80079-X  0.322
1963 Stern BD, Mechanic GL, Glimcher MJ, Goldhaber P. The resorption of bone collagen in tissue culture Biochemical and Biophysical Research Communications. 13: 137-143. DOI: 10.1016/0006-291X(63)90178-5  0.422
1959 Mechanic GL, Levy M. An [UNK]-Lysine Tripeptide Obtained from Collagen Journal of the American Chemical Society. 81: 1889-1892. DOI: 10.1021/ja01517a028  0.331
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