Scott W. Hiebert - Publications

Vanderbilt University, Nashville, TN 

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Stengel KR, Bhaskara S, Wang J, Liu Q, Ellis JD, Sampathi S, Hiebert SW. Histone deacetylase 3 controls a transcriptional network required for B cell maturation. Nucleic Acids Research. PMID 31586401 DOI: 10.1093/nar/gkz816  0.36
2017 Kim HG, LeGrand J, Swindle CS, Nick HJ, Oster RA, Chen D, Purohit-Ghelani S, Cotta CV, Ko R, Gartland L, Reddy V, Hiebert SW, Friedman AD, Klug CA. The assembly competence domain is essential for inv(16)-associated acute myeloid leukemia. Leukemia. PMID 28751774 DOI: 10.1038/leu.2017.236  0.4
2017 Stengel KR, Barnett KR, Wang J, Liu Q, Hodges E, Hiebert SW, Bhaskara S. Deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B-cell development. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739911 DOI: 10.1073/pnas.1701610114  0.36
2016 Chan E, Arlinghaus LR, Cardin DB, Goff L, Berlin JD, Parikh A, Abramson RG, Yankeelov TE, Hiebert S, Merchant N, Bhaskara S, Chakravarthy AB. Phase I trial of vorinostat added to chemoradiation with capecitabine in pancreatic cancer. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 27106554 DOI: 10.1016/j.radonc.2016.04.013  0.36
2015 Stengel KR, Zhao Y, Klus NJ, Kaiser JF, Gordy LE, Joyce S, Hiebert SW, Summers AR. Histone Deacetylase 3 Is Required for Efficient T Cell Development. Molecular and Cellular Biology. 35: 3854-65. PMID 26324326 DOI: 10.1128/MCB.00706-15  1
2015 Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, ... ... Hiebert SW, et al. Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells. Cell Stem Cell. 16: 477-87. PMID 25957903 DOI: 10.1016/j.stem.2015.04.008  1
2015 Wang L, Liu Y, Han R, Beier UH, Bhatti TR, Akimova T, Greene MI, Hiebert SW, Hancock WW. FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3. The Journal of Clinical Investigation. 125: 1111-23. PMID 25642770 DOI: 10.1172/JCI77088  1
2015 Poindexter SV, Reddy VK, Mittal MK, Williams AM, Washington MK, Harris E, Mah A, Hiebert SW, Singh K, Chaturvedi R, Wilson KT, Lund PK, Williams CS. Transcriptional corepressor MTG16 regulates small intestinal crypt proliferation and crypt regeneration after radiation-induced injury. American Journal of Physiology. Gastrointestinal and Liver Physiology. 308: G562-71. PMID 25573176 DOI: 10.1152/ajpgi.00253.2014  1
2015 Parang B, Rosenblatt D, Williams AD, Washington MK, Revetta F, Short SP, Reddy VK, Hunt A, Shroyer NF, Engel ME, Hiebert SW, Williams CS. The transcriptional corepressor MTGR1 regulates intestinal secretory lineage allocation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 786-95. PMID 25398765 DOI: 10.1096/fj.14-254284  1
2015 Stengel KR, Hiebert SW. Class I HDACs Affect DNA Replication, Repair, and Chromatin Structure: Implications for Cancer Therapy. Antioxidants & Redox Signaling. 23: 51-65. PMID 24730655 DOI: 10.1089/ars.2014.5915  1
2014 Ha K, Fiskus W, Choi DS, Bhaskara S, Cerchietti L, Devaraj SG, Shah B, Sharma S, Chang JC, Melnick AM, Hiebert S, Bhalla KN. Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells. Oncotarget. 5: 5637-50. PMID 25026298 DOI: 10.18632/ONCOTARGET.2154  1
2014 Ghosh HS, Ceribelli M, Matos I, Lazarovici A, Bussemaker HJ, Lasorella A, Hiebert SW, Liu K, Staudt LM, Reizis B. ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2. The Journal of Experimental Medicine. 211: 1623-35. PMID 24980046 DOI: 10.1084/jem.20132121  1
2013 Yan L, Womack B, Wotton D, Guo Y, Shyr Y, Davé U, Li C, Hiebert S, Brandt S, Hamid R. Tgif1 regulates quiescence and self-renewal of hematopoietic stem cells. Molecular and Cellular Biology. 33: 4824-33. PMID 24100014 DOI: 10.1128/MCB.01076-13  1
2013 Summers AR, Fischer MA, Stengel KR, Zhao Y, Kaiser JF, Wells CE, Hunt A, Bhaskara S, Luzwick JW, Sampathi S, Chen X, Thompson MA, Cortez D, Hiebert SW. HDAC3 is essential for DNA replication in hematopoietic progenitor cells. The Journal of Clinical Investigation. 123: 3112-23. PMID 23921131 DOI: 10.1172/JCI60806  1
2013 Hatzi K, Jiang Y, Huang C, Garrett-Bakelman F, Gearhart MD, Giannopoulou EG, Zumbo P, Kirouac K, Bhaskara S, Polo JM, Kormaksson M, MacKerell AD, Xue F, Mason CE, Hiebert SW, et al. A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters. Cell Reports. 4: 578-88. PMID 23911289 DOI: 10.1016/j.celrep.2013.06.016  0.36
2013 Wells CE, Bhaskara S, Stengel KR, Zhao Y, Sirbu B, Chagot B, Cortez D, Khabele D, Chazin WJ, Cooper A, Jacques V, Rusche J, Eischen CM, McGirt LY, Hiebert SW. Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma. Plos One. 8: e68915. PMID 23894374 DOI: 10.1371/journal.pone.0068915  1
2013 Thapa P, Das J, McWilliams D, Shapiro M, Sundsbak R, Nelson-Holte M, Tangen S, Anderson J, Desiderio S, Hiebert S, Sant'angelo DB, Shapiro VS. The transcriptional repressor NKAP is required for the development of iNKT cells. Nature Communications. 4: 1582. PMID 23481390 DOI: 10.1038/ncomms2580  1
2013 Ziesché E, Kettner-Buhrow D, Weber A, Wittwer T, Jurida L, Soelch J, Müller H, Newel D, Kronich P, Schneider H, Dittrich-Breiholz O, Bhaskara S, Hiebert SW, Hottiger MO, Li H, et al. The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB. Nucleic Acids Research. 41: 90-109. PMID 23087373 DOI: 10.1093/nar/gks916  1
2013 Williams CS, Bradley AM, Chaturvedi R, Singh K, Piazuelo MB, Chen X, McDonough EM, Schwartz DA, Brown CT, Allaman MM, Coburn LA, Horst SN, Beaulieu DB, Choksi YA, Washington MK, ... ... Hiebert SW, et al. MTG16 contributes to colonic epithelial integrity in experimental colitis. Gut. 62: 1446-55. PMID 22833394 DOI: 10.1136/gutjnl-2011-301439  1
2012 Barrett CW, Smith JJ, Lu LC, Markham N, Stengel KR, Short SP, Zhang B, Hunt AA, Fingleton BM, Carnahan RH, Engel ME, Chen X, Beauchamp RD, Wilson KT, Hiebert SW, et al. Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters. Plos One. 7: e51205. PMID 23251453 DOI: 10.1371/journal.pone.0051205  1
2012 Fischer MA, Moreno-Miralles I, Hunt A, Chyla BJ, Hiebert SW. Myeloid translocation gene 16 is required for maintenance of haematopoietic stem cell quiescence. The Embo Journal. 31: 1494-505. PMID 22266796 DOI: 10.1038/emboj.2011.500  1
2011 Zheng S, Tansey WP, Hiebert SW, Zhao Z. Integrative network analysis identifies key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma. Bmc Medical Genomics. 4: 62. PMID 21824427 DOI: 10.1186/1755-8794-4-62  1
2011 Wilson AJ, Holson E, Wagner F, Zhang YL, Fass DM, Haggarty SJ, Bhaskara S, Hiebert SW, Schreiber SL, Khabele D. The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells. Cancer Biology & Therapy. 12: 484-93. PMID 21738006 DOI: 10.4161/cbt.12.6.15956  1
2011 Sirbu BM, Couch FB, Feigerle JT, Bhaskara S, Hiebert SW, Cortez D. Analysis of protein dynamics at active, stalled, and collapsed replication forks. Genes & Development. 25: 1320-7. PMID 21685366 DOI: 10.1101/gad.2053211  1
2011 Hunt A, Fischer M, Engel ME, Hiebert SW. Mtg16/Eto2 contributes to murine T-cell development. Molecular and Cellular Biology. 31: 2544-51. PMID 21536648 DOI: 10.1128/MCB.01458-10  1
2011 Bhaskara S, Hiebert SW. Role for histone deacetylase 3 in maintenance of genome stability. Cell Cycle (Georgetown, Tex.). 10: 727-8. PMID 21311228 DOI: 10.4161/cc.10.5.14866  1
2011 Barrett CW, Fingleton B, Williams A, Ning W, Fischer MA, Washington MK, Chaturvedi R, Wilson KT, Hiebert SW, Williams CS. MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model. Cancer Research. 71: 1302-12. PMID 21303973 DOI: 10.1158/0008-5472.CAN-10-3317  1
2010 Bhaskara S, Knutson SK, Jiang G, Chandrasekharan MB, Wilson AJ, Zheng S, Yenamandra A, Locke K, Yuan JL, Bonine-Summers AR, Wells CE, Kaiser JF, Washington MK, Zhao Z, Wagner FF, ... ... Hiebert SW, et al. Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell. 18: 436-47. PMID 21075309 DOI: 10.1016/j.ccr.2010.10.022  1
2010 Razidlo DF, Whitney TJ, Casper ME, McGee-Lawrence ME, Stensgard BA, Li X, Secreto FJ, Knutson SK, Hiebert SW, Westendorf JJ. Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat. Plos One. 5: e11492. PMID 20628553 DOI: 10.1371/journal.pone.0011492  1
2010 Huang F, Chandrasekharan MB, Chen YC, Bhaskara S, Hiebert SW, Sun ZW. The JmjN domain of Jhd2 is important for its protein stability, and the plant homeodomain (PHD) finger mediates its chromatin association independent of H3K4 methylation. The Journal of Biological Chemistry. 285: 24548-61. PMID 20538609 DOI: 10.1074/jbc.M110.117333  1
2010 Engel ME, Hiebert SW. The enemy within: dormant retroviruses awaken. Nature Medicine. 16: 517-8. PMID 20448571 DOI: 10.1038/nm0510-517  1
2010 Compton LA, Hiebert SW. Anticancer therapy SMRT-ens up: targeting the BCL6-SMRT interaction in B cell lymphoma. Cancer Cell. 17: 315-6. PMID 20385356 DOI: 10.1016/j.ccr.2010.03.012  1
2010 Engel ME, Hiebert SW. Proleukemic RUNX1 and CBFbeta mutations in the pathogenesis of acute leukemia. Cancer Treatment and Research. 145: 127-47. PMID 20306249 DOI: 10.1007/978-0-387-69259-3_8  1
2010 Engel ME, Nguyen HN, Mariotti J, Hunt A, Hiebert SW. Myeloid translocation gene 16 (MTG16) interacts with Notch transcription complex components to integrate Notch signaling in hematopoietic cell fate specification. Molecular and Cellular Biology. 30: 1852-63. PMID 20123979 DOI: 10.1128/MCB.01342-09  1
2009 Cai Y, Xu Z, Xie J, Ham AJ, Koury MJ, Hiebert SW, Brandt SJ. Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors. Biochemical and Biophysical Research Communications. 390: 295-301. PMID 19799863 DOI: 10.1016/j.bbrc.2009.09.111  1
2009 Yan M, Ahn EY, Hiebert SW, Zhang DE. RUNX1/AML1 DNA-binding domain and ETO/MTG8 NHR2-dimerization domain are critical to AML1-ETO9a leukemogenesis. Blood. 113: 883-6. PMID 19036704 DOI: 10.1182/blood-2008-04-153742  1
2008 Chyla BJ, Moreno-Miralles I, Steapleton MA, Thompson MA, Bhaskara S, Engel M, Hiebert SW. Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation. Molecular and Cellular Biology. 28: 6234-47. PMID 18710942 DOI: 10.1128/MCB.00404-08  1
2008 Farmer TE, Williams CS, Washington MK, Hiebert SW. Inactivation of the p19(ARF) tumor suppressor affects intestinal epithelial cell proliferation and integrity. Journal of Cellular Biochemistry. 104: 2228-40. PMID 18442038 DOI: 10.1002/jcb.21779  1
2008 Bhaskara S, Chyla BJ, Amann JM, Knutson SK, Cortez D, Sun ZW, Hiebert SW. Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control. Molecular Cell. 30: 61-72. PMID 18406327 DOI: 10.1016/j.molcel.2008.02.030  1
2008 Knutson SK, Chyla BJ, Amann JM, Bhaskara S, Huppert SS, Hiebert SW. Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks. The Embo Journal. 27: 1017-28. PMID 18354499 DOI: 10.1038/emboj.2008.51  1
2008 Moore AC, Amann JM, Williams CS, Tahinci E, Farmer TE, Martinez JA, Yang G, Luce KS, Lee E, Hiebert SW. Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription. Molecular and Cellular Biology. 28: 977-87. PMID 18039847 DOI: 10.1128/MCB.01242-07  1
2008 Hanson CA, Wood LD, Hiebert SW. Cellular stress triggers TEL nuclear export via two genetically separable pathways. Journal of Cellular Biochemistry. 104: 488-98. PMID 18022807 DOI: 10.1002/jcb.21637  1
2007 Yang G, Thompson MA, Brandt SJ, Hiebert SW. Histone deacetylase inhibitors induce the degradation of the t(8;21) fusion oncoprotein. Oncogene. 26: 91-101. PMID 16799637 DOI: 10.1038/sj.onc.1209760  1
2006 Martinez JA, Williams CS, Amann JM, Ellis TC, Moreno-Miralles I, Washington MK, Gregoli P, Hiebert SW. Deletion of Mtgr1 sensitizes the colonic epithelium to dextran sodium sulfate-induced colitis. Gastroenterology. 131: 579-88. PMID 16890610 DOI: 10.1053/j.gastro.2006.06.009  1
2006 Reed-Inderbitzin E, Moreno-Miralles I, Vanden-Eynden SK, Xie J, Lutterbach B, Durst-Goodwin KL, Luce KS, Irvin BJ, Cleary ML, Brandt SJ, Hiebert SW. RUNX1 associates with histone deacetylases and SUV39H1 to repress transcription Oncogene. 25: 5777-5786. PMID 16652147 DOI: 10.1038/sj.onc.1209591  1
2005 Amann JM, Chyla BJ, Ellis TC, Martinez A, Moore AC, Franklin JL, McGhee L, Meyers S, Ohm JE, Luce KS, Ouelette AJ, Washington MK, Thompson MA, King D, Gautam S, ... ... Hiebert SW, et al. Mtgr1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine. Molecular and Cellular Biology. 25: 9576-85. PMID 16227606 DOI: 10.1128/MCB.25.21.9576-9585.2005  1
2005 Moreno-Miralles I, Pan L, Keates-Baleeiro J, Durst-Goodwin K, Yang C, Kim HG, Thompson MA, Klug CA, Cleveland JL, Hiebert SW. The inv(16) cooperates with ARF haploinsufficiency to induce acute myeloid leukemia. The Journal of Biological Chemistry. 280: 40097-103. PMID 16199529 DOI: 10.1074/jbc.M506855200  1
2005 Linggi BE, Brandt SJ, Sun ZW, Hiebert SW. Translating the histone code into leukemia. Journal of Cellular Biochemistry. 96: 938-50. PMID 16167339 DOI: 10.1002/jcb.20604  1
2005 Ice RJ, Wildonger J, Mann RS, Hiebert SW. Comment on "Nervy links protein kinase A to plexin-mediated semaphorin repulsion". Science (New York, N.Y.). 309: 558; author reply 55. PMID 16040690 DOI: 10.1126/science.1108719  1
2005 Yang G, Khalaf W, van de Locht L, Jansen JH, Gao M, Thompson MA, van der Reijden BA, Gutmann DH, Delwel R, Clapp DW, Hiebert SW. Transcriptional repression of the Neurofibromatosis-1 tumor suppressor by the t(8;21) fusion protein. Molecular and Cellular Biology. 25: 5869-79. PMID 15988004 DOI: 10.1128/MCB.25.14.5869-5879.2005  1
2004 Durst KL, Hiebert SW. Role of RUNX family members in transcriptional repression and gene silencing. Oncogene. 23: 4220-4. PMID 15156176 DOI: 10.1038/sj.onc.1207122  1
2004 van Wijnen AJ, Stein GS, Gergen JP, Groner Y, Hiebert SW, Ito Y, Liu P, Neil JC, Ohki M, Speck N. Nomenclature for Runt-related (RUNX) proteins. Oncogene. 23: 4209-10. PMID 15156174 DOI: 10.1038/sj.onc.1207758  1
2004 Yang G, Khalaf W, van de Locht L, Jansen JH, van der Reijden BA, Müller-Tidow C, Delwel HR, Serve H, Clapp DW, Hiebert SW. Epigenetic regulation of tumor suppressors in t(8:21)-containing AML. Annals of Hematology. 83: 329-30. PMID 15052372 DOI: 10.1007/s00277-003-0841-8  1
2004 Müller-Tidow C, Steffen B, Cauvet T, Tickenbrock L, Ji P, Diederichs S, Sargin B, Köhler G, Stelljes M, Puccetti E, Ruthardt M, deVos S, Hiebert SW, Koeffler HP, Berdel WE, et al. Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells. Molecular and Cellular Biology. 24: 2890-904. PMID 15024077 DOI: 10.1128/MCB.24.7.2890-2904.2004  1
2004 Irvin BJ, Hiebert SW. AML-1 steps up to the platelets. Nature Medicine. 10: 238-9. PMID 14991045 DOI: 10.1038/nm0304-238  1
2003 Irvin BJ, Wood LD, Wang L, Fenrick R, Sansam CG, Packham G, Kinch M, Yang E, Hiebert SW. TEL, a putative tumor suppressor, induces apoptosis and represses transcription of Bcl-XL. The Journal of Biological Chemistry. 278: 46378-86. PMID 12960174 DOI: 10.1074/jbc.M305189200  1
2003 Steffen B, Serve H, Berdel WE, Agrawal S, Linggi B, Büchner T, Hiebert SW, Müller-Tidow C. Specific protein redirection as a transcriptional therapy approach for t(8;21) leukemia. Proceedings of the National Academy of Sciences of the United States of America. 100: 8448-53. PMID 12819347 DOI: 10.1073/pnas.1330293100  1
2003 Hiebert SW, Reed-Inderbitzin EF, Amann J, Irvin B, Durst K, Linggi B. The t(8;21) fusion protein contacts co-repressors and histone deacetylases to repress the transcription of the p14ARF tumor suppressor. Blood Cells, Molecules & Diseases. 30: 177-83. PMID 12732181 DOI: 10.1016/S1079-9796(03)00021-4  1
2003 Wood LD, Irvin BJ, Nucifora G, Luce KS, Hiebert SW. Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 100: 3257-62. PMID 12626745 DOI: 10.1073/pnas.0637114100  1
2003 Durst KL, Lutterbach B, Kummalue T, Friedman AD, Hiebert SW. The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain. Molecular and Cellular Biology. 23: 607-19. PMID 12509458 DOI: 10.1128/MCB.23.2.607-619.2003  1
2002 Barseguian K, Lutterbach B, Hiebert SW, Nickerson J, Lian JB, Stein JL, van Wijnen AJ, Stein GS. Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins. Proceedings of the National Academy of Sciences of the United States of America. 99: 15434-9. PMID 12427969 DOI: 10.1073/pnas.242588499  1
2002 King D, Yang G, Thompson MA, Hiebert SW. Loss of neurofibromatosis-1 and p19(ARF) cooperate to induce a multiple tumor phenotype. Oncogene. 21: 4978-82. PMID 12118376 DOI: 10.1038/sj.onc.1205632  1
2002 de Guzman CG, Warren AJ, Zhang Z, Gartland L, Erickson P, Drabkin H, Hiebert SW, Klug CA. Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation. Molecular and Cellular Biology. 22: 5506-17. PMID 12101243 DOI: 10.1128/MCB.22.15.5506-5517.2002  1
2002 Linggi B, Müller-Tidow C, van de Locht L, Hu M, Nip J, Serve H, Berdel WE, van der Reijden B, Quelle DE, Rowley JD, Cleveland J, Jansen JH, Pandolfi PP, Hiebert SW. The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia. Nature Medicine. 8: 743-50. PMID 12091906 DOI: 10.1038/nm726  1
2001 Eischen CM, Packham G, Nip J, Fee BE, Hiebert SW, Zambetti GP, Cleveland JL. Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1 Oncogene. 20: 6983-6993. PMID 11704823 DOI: 10.1038/sj.onc.1204892  1
2001 Hiebert SW, Lutterbach B, Durst K, Wang L, Linggi B, Wu S, Wood L, Amann J, King D, Hou Y. Mechanisms of transcriptional repression by the t(8;21)-, t(12;21)-, and inv(16)-encoded fusion proteins Cancer Chemotherapy and Pharmacology. 48. PMID 11587363 DOI: 10.1007/s002800100302  1
2001 Hiebert SW, Lutterbach B, Amann J. Role of co-repressors in transcriptional repression mediated by the t(8;21), t(16;21), t(12;21), and inv(16) fusion proteins Current Opinion in Hematology. 8: 197-200. PMID 11561155 DOI: 10.1097/00062752-200107000-00003  1
2001 Amann JM, Nip J, Strom DK, Lutterbach B, Harada H, Lenny N, Downing JR, Meyers S, Hiebert SW. ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain Molecular and Cellular Biology. 21: 6470-6483. PMID 11533236 DOI: 10.1128/MCB.21.19.6470-6483.2001  1
2001 Wang L, Hiebert SW. TEL contacts multiple co-repressors and specifically associates with histone deacetylase-3 Oncogene. 20: 3716-3725. PMID 11439334 DOI: 10.1038/sj.onc.1204479  1
2001 Nip J, Strom DK, Eischen CM, Cleveland JL, Zambetti GP, Hiebert SW. E2F-1 induces the stabilization of p53 but blocks p53-mediated transactivation Oncogene. 20: 910-920. PMID 11314026 DOI: 10.1038/sj.onc.1204171  1
2000 Meyers S, Hiebert SW. Alterations in subnuclear trafficking of nuclear regulatory factors in acute leukemia Journal of Cellular Biochemistry. Supplement. 93-98. PMID 11389537  1
2000 Nip J, Hiebert SW. Topoisomerase IIα mediates E2F-1-induced chemosensitivity and is a target for p53-mediated transcriptional repression Cell Biochemistry and Biophysics. 33: 199-207. PMID 11325040  1
2000 Melnick A, Carlile GW, McConnell MJ, Polinger A, Hiebert SW, Licht JD. AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein. Blood. 96: 3939-47. PMID 11090081  1
2000 Fenrick R, Wang L, Nip J, Amann JM, Rooney RJ, Walker-Daniels J, Crawford HC, Hulboy DL, Kinch MS, Matrisian LM, Hiebert SW. TEL, a putative tumor suppressor, modulates cell growth and cell morphology of ras-transformed cells while repressing the transcription of stromelysin-1. Molecular and Cellular Biology. 20: 5828-39. PMID 10913166 DOI: 10.1128/MCB.20.16.5828-5839.2000  1
2000 Lutterbach B, Hiebert SW. Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation Gene. 245: 223-235. PMID 10717473 DOI: 10.1016/S0378-1119(00)00014-7  1
2000 Melnick AM, Westendorf JJ, Polinger A, Carlile GW, Arai S, Ball HJ, Lutterbach B, Hiebert SW, Licht JD. The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein Molecular and Cellular Biology. 20: 2075-2086. PMID 10688654 DOI: 10.1128/MCB.20.6.2075-2086.2000  1
2000 Strom DK, John N, Westendorf JJ, Linggi B, Lutterbach B, Downing JR, Lenny N, Hiebert SW. Expression of the AML-1 oncogene shortens the G1 phase of the cell cycle Journal of Biological Chemistry. 275: 3438-3445. PMID 10652337 DOI: 10.1074/jbc.275.5.3438  1
2000 Lutterbach B, Westendorf JJ, Linggi B, Isaac S, Seto E, Hiebert SW. A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia Journal of Biological Chemistry. 275: 651-656. PMID 10617663 DOI: 10.1074/jbc.275.1.651  1
2000 Meyers S, Hiebert SW. Changes in sub-nuclear structures and functional perturbations: Implications for radiotherapy Journal of Cellular Biochemistry. 80: 142-150.  1
2000 Melnick AM, Carlile G, Hiebert SW, Licht JD. The eto protein is a corepressor for several wild-type and oncogenic hematopoietic transcription factors Blood. 96.  1
1999 Westendorf JJ, Hiebert SW. Mammalian runt-domain proteins and their roles in hematopoiesis, osteogenesis, and leukemia Journal of Cellular Biochemistry. 76: 51-58. PMID 10629103  1
1999 Lutterbach B, Hou Y, Durst KL, Hiebert SW. The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor. Proceedings of the National Academy of Sciences of the United States of America. 96: 12822-7. PMID 10536006 DOI: 10.1073/pnas.96.22.12822  1
1999 Fenrick R, Amann JM, Lutterbach B, Wang L, Westendorf JJ, Downing JR, Hiebert SW. Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein Molecular and Cellular Biology. 19: 6566-6574. PMID 10490596  1
1999 Westendorf JJ, Mernaugh R, Hiebert SW. Identification and characterization of a protein containing formin homology (FH1/FH2) domains Gene. 232: 173-182. PMID 10352228 DOI: 10.1016/S0378-1119(99)00127-4  1
1998 Fenrick R, Hiebert SW. Role of histone deacetylases in acute leukemia Journal of Cellular Biochemistry. Supplement. 30: 194-202. PMID 9893271  1
1998 Lutterbach B, Westendorf JJ, Linggi B, Patten A, Moniwa M, Davie JR, Huynh KD, Bardwell VJ, Lavinsky RM, Rosenfeld MG, Glass C, Seto E, Hiebert SW. ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Molecular and Cellular Biology. 18: 7176-84. PMID 9819404  1
1998 Petrovick MS, Hiebert SW, Friedman AD, Hetherington CJ, Tenen DG, Zhang DE. Multiple functional domains of AML1: PU.1 and C/EBPα synergize with different regions of AML1 Molecular and Cellular Biology. 18: 3915-3925. PMID 9632776  1
1998 Lutterbach B, Sun D, Schuetz J, Hiebert SW. The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein Molecular and Cellular Biology. 18: 3604-3611. PMID 9584201  1
1998 Ji C, Casinghino S, Chang DJ, Chen Y, Javed A, Ito Y, Hiebert SW, Lian JB, Stein GS, McCarthy TL, Centrella M. CBFa(AML/PEBP2)-related elements in the TGF-β type I receptor promoter and expression with osteoblast differentiation Journal of Cellular Biochemistry. 69: 353-363. PMID 9581873 DOI: 10.1002/(SICI)1097-4644(19980601)69:3<353::AID-JCB12>3.0.CO;2-D  1
1998 Zeng C, McNeil S, Pockwinse S, Nickerson J, Shopland L, Lawrence JB, Penman S, Hiebert S, Lian JB, van Wijnen AJ, Stein JL, Stein GS. Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains. Proceedings of the National Academy of Sciences of the United States of America. 95: 1585-9. PMID 9465059 DOI: 10.1073/pnas.95.4.1585  1
1998 Strom DK, Cleveland JL, Chellappan S, Nip J, Hiebert SW. E2F-1 and E2F-3 are functionally distinct in their ability to promote myeloid cell cycle progression and block granulocyte differentiation. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 9: 59-69. PMID 9438389  1
1998 Westendorf JJ, Yamamoto CM, Lenny N, Downing JR, Selsted ME, Hiebert SW. The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-α, inhibits C/EBP-α-dependent transcription, and blocks granulocytic differentiation Molecular and Cellular Biology. 18: 322-333. PMID 9418879  1
1997 Lenny N, Westendorf JJ, Hiebert SW. Transcriptional regulation during myelopoiesis Molecular Biology Reports. 24: 157-168. PMID 9291089 DOI: 10.1023/A:1006859700409  1
1997 Banerjee C, McCabe LR, Choi JY, Hiebert SW, Stein JL, Stein GS, Lian JB. Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex Journal of Cellular Biochemistry. 66: 1-8. PMID 9215522 DOI: 10.1002/(SICI)1097-4644(19970701)66:1<1::AID-JCB1>3.0.CO;2-V  1
1997 Zeng C, van Wijnen AJ, Stein JL, Meyers S, Sun W, Shopland L, Lawrence JB, Penman S, Lian JB, Stein GS, Hiebert SW. Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 94: 6746-51. PMID 9192636 DOI: 10.1073/pnas.94.13.6746  1
1997 Nip J, Strom DK, Fee BE, Zambetti G, Cleveland JL, Hiebert SW. E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis Molecular and Cellular Biology. 17: 1049-1056. PMID 9032231  1
1996 Rhoades KL, Hetherington CJ, Rowley JD, Hiebert SW, Nucifora G, Tenen DG, Zhang DE. Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis Proceedings of the National Academy of Sciences of the United States of America. 93: 11895-11900. PMID 8876234 DOI: 10.1073/pnas.93.21.11895  1
1996 Meyers S, Lenny N, Sun W, Hiebert SW. AML-2 is a potential target for transcriptional regulation by the t(8;21) and t(12;21) fusion proteins in acute leukemia Oncogene. 13: 303-312. PMID 8710369  1
1996 Hiebert SW, Sun W, Davis JN, Golub T, Shurtleff S, Buijs A, Downing JR, Grosveld G, Roussell MF, Gilliland DG, Lenny N, Meyers S. The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription. Molecular and Cellular Biology. 16: 1349-55. PMID 8657108  1
1996 Banerjee C, Hiebert SW, Stein JL, Lian JB, Stein GS. An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the osteocalcin gene Proceedings of the National Academy of Sciences of the United States of America. 93: 4968-4973. PMID 8643513 DOI: 10.1073/pnas.93.10.4968  1
1996 Zhang DE, Hetherington CJ, Meyers S, Rhoades KL, Larson CJ, Chen - HM, Hiebert SW, Tenen DG. CCAAT enhancer-binding protein (C/EBP) and AML1 (CBFα2) synergistically activate the macrophage colony-stimulating factor receptor promoter Molecular and Cellular Biology. 16: 1231-1240. PMID 8622667  1
1996 Hitomi M, Shu J, Strom D, Hiebert SW, Harter ML, Stacey DW. Prostaglandin A2 blocks the activation of G1 phase cyclin-dependent kinase without altering mitogen-activated protein kinase stimulation Journal of Biological Chemistry. 271: 9376-9383. PMID 8621603 DOI: 10.1074/jbc.271.16.9376  1
1996 Hiebert SW, Downing JR, Lenny N, Meyers S. Transcriptional regulation by the t(8;21) fusion protein, AML-1/ETO Current Topics in Microbiology and Immunology. 211: 253-258. PMID 8585956  1
1996 Okuda T, Van Deursen J, Hiebert SW, Grosveld G, Downing JR. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis Cell. 84: 321-330. PMID 8565077 DOI: 10.1016/S0092-8674(00)80986-1  1
1995 Meyers S, Hiebert SW. Indirect and direct disruption of transcriptional regulation in cancer: E2F and AML-1 Critical Reviews in Eukaryotic Gene Expression. 5: 365-383. PMID 8834231  1
1995 Frank R, Zhang J, Uchida H, Meyers S, Hiebert SW, Nimer SD. The AML1/ETO fusion protein blocks transactivation of the GM-CSF promoter by AML1B Oncogene. 11: 2666-2674. PMID 8545124  1
1995 Hiebert SW, Packham G, Strom DK, Haffner R, Oren M, Zambetti G, Cleveland JL. E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis Molecular and Cellular Biology. 15: 6864-6874. PMID 8524253  1
1995 Meyers S, Lenny N, Hiebert SW. The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation Molecular and Cellular Biology. 15: 1974-1982. PMID 7891692  1
1995 Shurtleff SA, Meyers S, Hiebert SW, Raimondi SC, Head DR, Willman CL, Wolman S, Slovak ML, Carroll AJ, Behm F, Hulshof MG, Motroni TA, Okuda T, Liu P, Collins FS, et al. Heterogeneity in CBFβ/MYH11 fusion messages encoded by the inv(16)(p13q22) and the t(16;16)(p13;q22) in acute myelogenous leukemia Blood. 85: 3695-3703. PMID 7780153  1
1995 Golub TR, Barker GF, Bohlander SK, Hiebert SW, Ward DC, Bray-Ward P, Morgan E, Raimondi SC, Rowley JD, Gilliland DG. Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 92: 4917-21. PMID 7761424 DOI: 10.1073/pnas.92.11.4917  1
1995 Merriman HL, Van Wijnen AJ, Hiebert S, Bidwell JP, Fey E, Lian J, Stein J, Stein GS. The tissue-specific nuclear matrix protein, NMP-2, is a member of the AML/CBF/PEBP2/runt domain transcription factor family: Interactions with the osteocalcin gene promoter Biochemistry. 34: 13125-13132. PMID 7548073  1
1995 Lenny N, Meyers S, Hiebert SW. Functional domains of the t(8;21) fusion protein, AML-1/ETO Oncogene. 11: 1760-1769. PMID 7478604  1
1994 Roussel MF, Davis JN, Cleveland JL, Ghysdael J, Hiebert SW. Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1 Oncogene. 9: 404-415. PMID 8290253  1
1994 Dobrowolski SF, Stacey DW, Harter ML, Stine JT, Hiebert SW. An E2F dominant negative mutant blocks E1A induced cell cycle progression Oncogene. 9: 2605-2612. PMID 8058324  1
1994 Nuchprayoon I, Meyers S, Scott LM, Suzow J, Hiebert S, Friedman AD. PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells. Molecular and Cellular Biology. 14: 5558-68. PMID 8035830 DOI: 10.1128/MCB.14.8.5558  1
1993 Hiebert SW. Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter reppression and pRb-mediated growth suppression Molecular and Cellular Biology. 13: 3384-3391. PMID 8497257  1
1993 Kato J, Matsushime H, Hiebert SW, Ewen ME, Sherr CJ. Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4 Genes and Development. 7: 331-342. PMID 8449399  1
1993 Meyers S, Downing JR, Hiebert SW. Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: The runt homology domain is required for DNA binding and protein-protein interactions Molecular and Cellular Biology. 13: 6336-6345. PMID 8413232  1
1992 Hiebert SW, Chellappan SP, Horowitz JM, Nevins JR. The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F Genes and Development. 6: 177-185. PMID 1531329  1
1991 Nevins JR, Chellappan SP, Mudryj M, Hiebert S, Devoto S, Horowitz J, Hunter T, Pines J. E2F transcription factor is a target for the RB protein and the cyclin A protein Cold Spring Harbor Symposia On Quantitative Biology. 56: 157-162. PMID 1840249 DOI: 10.1101/SQB.1991.056.01.020  1
1991 Mudryj M, Devoto SH, Hiebert SW, Hunter T, Pines J, Nevins JR. Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A Cell. 65: 1243-1253. PMID 1829647 DOI: 10.1016/0092-8674(91)90019-U  1
1991 Chellappan SP, Hiebert S, Mudryj M, Horowitz JM, Nevins JR. The E2F transcription factor is a cellular target for the RB protein Cell. 65: 1053-1061. PMID 1828392 DOI: 10.1016/0092-8674(91)90557-F  1
1991 Hiebert SW, Blake M, Azizkhan J, Nevins JR. Role of E2F transcription factor in E1A-mediated trans activation of cellular genes Journal of Virology. 65: 3547-3552. PMID 1828272  1
1990 Ng DT, Hiebert SW, Lamb RA. Different roles of individual N-linked oligosaccharide chains in folding, assembly, and transport of the simian virus 5 hemagglutinin-neuraminidase. Molecular and Cellular Biology. 10: 1989-2001. PMID 2183015  1
1990 Mudryj M, Hiebert SW, Nevins JR. A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway Embo Journal. 9: 2179-2184. PMID 2141565  1
1989 Young KS, Weigel R, Hiebert S, Nevins JR. Adenovirus E1A-mediated negative control of genes activated during F9 differentiation Molecular and Cellular Biology. 9: 3109-3113. PMID 2528683 DOI: 10.1128/MCB.9.7.3109  1
1989 Hiebert SW, Lipp M, Nevins JR. E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor Proceedings of the National Academy of Sciences of the United States of America. 86: 3594-3598. PMID 2524830  1
1988 Hiebert SW, Lamb RA. Cell surface expression of glycosylated, nonglycosylated, and truncated forms of a cytoplasmic protein pyruvate kinase. The Journal of Cell Biology. 107: 865-76. PMID 3047152  1
1988 Hiebert SW, Richardson CD, Lamb RA. Cell surface expression and orientation in membranes of the 44-amino-acid SH protein of simian virus 5. Journal of Virology. 62: 2347-57. PMID 2836617  1
1988 Lamb RA, Hiebert SW, Hull JD, Ng D, Williams MA, Zebedee SL. Structure, modification, intracellular transport and function of influenza and paramyxovirus integral membrane proteins Virus Research. 11: 10.  1
1986 Hiebert SW, Williams MA, Lamb RA. Nucleotide sequence of RNA segment 7 of influenza B/Singapore/222/79: maintenance of a second large open reading frame. Virology. 155: 747-51. PMID 3788064 DOI: 10.1016/0042-6822(86)90237-0  1
1985 Hiebert SW, Paterson RG, Lamb RA. Identification and predicted sequence of a previously unrecognized small hydrophobic protein, SH, of the paramyxovirus simian virus 5. Journal of Virology. 55: 744-51. PMID 4020965  1
1985 Hiebert SW, Paterson RG, Lamb RA. Hemagglutinin-neuraminidase protein of the paramyxovirus simian virus 5: nucleotide sequence of the mRNA predicts an N-terminal membrane anchor. Journal of Virology. 54: 1-6. PMID 3973974  1
1985 Paterson RG, Hiebert SW, Lamb RA. Expression at the cell surface of biologically active fusion and hemagglutinin/neuraminidase proteins of the paramyxovirus simian virus 5 from cloned cDNA. Proceedings of the National Academy of Sciences of the United States of America. 82: 7520-4. PMID 3865176  1
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