| Year |
Citation |
Score |
| 2022 |
Goodwin KD, Lewis MA, Long EC, Georgiadis MM. Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A and B bound to duplex 5'-TAGTT sites. Bioorganic & Medicinal Chemistry. 77: 117113. PMID 36516684 DOI: 10.1016/j.bmc.2022.117113 |
0.622 |
|
| 2021 |
Chaturvedi R, Long EC. Mechanistic studies of dinucleotide and oligonucleotide model cyclobutane pyrimidine dimer (CPD) DNA lesions under alkaline conditions. Bioorganic & Medicinal Chemistry. 54: 116499. PMID 34922308 DOI: 10.1016/j.bmc.2021.116499 |
0.754 |
|
| 2016 |
Opperman TJ, Kwasny SM, Li JB, Lewis MA, Aiello D, Williams JD, Peet NP, Moir DT, Bowlin TL, Long EC. DNA Targeting as a Likely Mechanism Underlying the Antibacterial Activity of Synthetic Bis-indole Antibiotics. Antimicrobial Agents and Chemotherapy. PMID 27620482 DOI: 10.1128/Aac.00309-16 |
0.651 |
|
| 2016 |
Wang H, Cai S, Bailey BJ, Reza Saadatzadeh M, Ding J, Tonsing-Carter E, Georgiadis TM, Zachary Gunter T, Long EC, Minto RE, Gordon KR, Sen SE, Cai W, Eitel JA, Waning DL, et al. Combination therapy in a xenograft model of glioblastoma: enhancement of the antitumor activity of temozolomide by an MDM2 antagonist. Journal of Neurosurgery. 1-14. PMID 27177180 DOI: 10.3171/2016.1.Jns152513 |
0.306 |
|
| 2015 |
Tonsing-Carter E, Bailey BJ, Saadatzadeh MR, Ding J, Wang H, Sinn AL, Peterman KM, Spragins TK, Silver JM, Sprouse AA, Georgiadis TM, Gunter TZ, Long EC, Minto RE, Marchal CC, et al. Potentiation of carboplatin-mediated DNA damage by the Mdm2 modulator Nutlin-3a in a humanized orthotopic breast-to-lung metastatic model. Molecular Cancer Therapeutics. PMID 26494859 DOI: 10.1158/1535-7163.Mct-15-0237 |
0.319 |
|
| 2014 |
Lewis MA, Williams KM, Fang YY, Schultz FA, Long EC. DNA Cleaving "Tandem-Array" Metallopeptides Activated With KHSO5: Towards the Development of Multi-Metallated Bioactive Conjugates and Compounds. Current Bioactive Compounds. 10: 13-20. PMID 25408625 DOI: 10.2174/157340721001140724150901 |
0.571 |
|
| 2014 |
Lin G, Jian Y, Dria KJ, Long EC, Li L. Reactivity of damaged pyrimidines: DNA cleavage via hemiaminal formation at the C4 positions of the saturated thymine of spore photoproduct and dihydrouridine. Journal of the American Chemical Society. 136: 12938-46. PMID 25127075 DOI: 10.1021/Ja505407P |
0.42 |
|
| 2014 |
Garner ML, Georgiadis TM, Li JB, Wang T, Long EC. Solid-phase synthesis of amidine-substituted phenylbenzimidazoles and incorporation of this DNA binding and recognition motif into amino acid and peptide conjugates. Amino Acids. 46: 1297-303. PMID 24562478 DOI: 10.1007/S00726-014-1691-5 |
0.399 |
|
| 2010 |
Fang YY, Morris VR, Lingani GM, Long EC, Southerland WM. Genome-Targeted Drug Design: Understanding the Netropsin-DNA Interaction. The Open Conference Proceedings Journal. 1: 157-163. PMID 21297883 |
0.405 |
|
| 2010 |
Laing BM, Barrow-Laing L, Harrington M, Long EC, Bergstrom DE. Properties of double-stranded oligonucleotides modified with lipophilic substituents. Bioconjugate Chemistry. 21: 1537-44. PMID 20672836 DOI: 10.1021/Bc100201N |
0.341 |
|
| 2010 |
Bapat A, Glass LS, Luo M, Fishel ML, Long EC, Georgiadis MM, Kelley MR. Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells. The Journal of Pharmacology and Experimental Therapeutics. 334: 988-98. PMID 20504914 DOI: 10.1124/Jpet.110.169128 |
0.355 |
|
| 2010 |
Glass LS, Bapat A, Kelley MR, Georgiadis MM, Long EC. Semi-automated high-throughput fluorescent intercalator displacement-based discovery of cytotoxic DNA binding agents from a large compound library. Bioorganic & Medicinal Chemistry Letters. 20: 1685-8. PMID 20144868 DOI: 10.1016/J.Bmcl.2010.01.033 |
0.451 |
|
| 2010 |
Wang H, Cai S, Bailey BJ, Sinn AL, Silver JM, Minto RE, Georgiadis TM, Long EC, Sarkaria JN, Mayo LD, Pollok KE. Abstract 5373: Modulation of temozolomide-mediated DNA damage in glioblastoma multiforme by the HDM2 antagonist, nutlin3 Cancer Research. 70: 5373-5373. DOI: 10.1158/1538-7445.Am10-5373 |
0.42 |
|
| 2010 |
Bapat A, Glass LS, Luo M, Fishel ML, Reed A, Long EC, Georgiadis MM, Kelley MR. Abstract 1963: Novel small molecule inhibitor of the endonuclease function of the APE1 DNA repair and redox signaling enzyme blocks proliferation and reduces viability of glioblastoma cells Cellular and Molecular Biology. 70: 1963-1963. DOI: 10.1158/1538-7445.Am10-1963 |
0.386 |
|
| 2010 |
Long EC. ChemInform Abstract: Ni(II)×Xaa-Xaa-His Metallopeptide - DNA/RNA Interactions Cheminform. 30: no-no. DOI: 10.1002/chin.199952290 |
0.336 |
|
| 2009 |
Glass LS, Nguyen B, Goodwin KD, Dardonville C, Wilson WD, Long EC, Georgiadis MM. Crystal structure of a trypanocidal 4,4'-bis(imidazolinylamino)diphenylamine bound to DNA. Biochemistry. 48: 5943-52. PMID 19405506 DOI: 10.1021/Bi900204W |
0.43 |
|
| 2009 |
Long EC, Fang YY, Lewis MA. DNA minor groove recognition by Ni(II)· and Cu(II)·Gly-Gly- His derived metallopeptides: Models of protein and natural product DNA recognition Acs Symposium Series. 1012: 219-241. DOI: 10.1021/bk-2009-1012.ch014 |
0.416 |
|
| 2008 |
Goodwin KD, Lewis MA, Long EC, Georgiadis MM. Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding. Proceedings of the National Academy of Sciences of the United States of America. 105: 5052-6. PMID 18362349 DOI: 10.1073/Pnas.0708143105 |
0.659 |
|
| 2008 |
Georgiadis M, Goodwin K, Lewis M, Long E. Crystal structures of DNA-bound Co(III)·bleomycins Acta Crystallographica Section a Foundations of Crystallography. 64: C156-C156. DOI: 10.1107/S0108767308094968 |
0.318 |
|
| 2007 |
Hamada H, Abe Y, Nagane R, Fang YY, Lewis MA, Long EC, Chikira M. DNA-fiber EPR investigation of the influence of amino-terminal residue stereochemistry on the DNA binding orientation of Cu(II).Gly-Gly-His-derived metallopeptides. Journal of Inorganic Biochemistry. 101: 1529-36. PMID 17706784 DOI: 10.1016/J.Jinorgbio.2007.06.034 |
0.626 |
|
| 2007 |
Jin Y, Lewis MA, Gokhale NH, Long EC, Cowan JA. Influence of stereochemistry and redox potentials on the single- and double-strand DNA cleavage efficiency of Cu(II) and Ni(II) Lys-Gly-His-derived ATCUN metallopeptides. Journal of the American Chemical Society. 129: 8353-61. PMID 17552522 DOI: 10.1021/Ja0705083 |
0.643 |
|
| 2007 |
Tanious FA, Laine W, Peixoto P, Bailly C, Goodwin KD, Lewis MA, Long EC, Georgiadis MM, Tidwell RR, Wilson WD. Unusually strong binding to the DNA minor groove by a highly twisted benzimidazole diphenylether: induced fit and bound water. Biochemistry. 46: 6944-56. PMID 17506529 DOI: 10.1021/Bi700288G |
0.608 |
|
| 2006 |
Fang YY, Lipkowitz KB, Long EC. Molecular Dynamics Simulations of the Orientation of Ni(II)•Gly-Gly-His and Ni(II)•Arg-Gly-His Metallopeptide-DNA Association. Journal of Chemical Theory and Computation. 2: 1453-63. PMID 26626853 DOI: 10.1021/Ct600074R |
0.517 |
|
| 2006 |
Goodwin KD, Lewis MA, Tanious FA, Tidwell RR, Wilson WD, Georgiadis MM, Long EC. A high-throughput, high-resolution strategy for the study of site-selective DNA binding agents: analysis of a "highly twisted" benzimidazole-diamidine. Journal of the American Chemical Society. 128: 7846-54. PMID 16771498 DOI: 10.1021/Ja0600936 |
0.584 |
|
| 2006 |
Fang YY, Claussen CA, Lipkowitz KB, Long EC. Diastereoselective DNA cleavage recognition by Ni(II) x Gly-Gly-His-derived metallopeptides. Journal of the American Chemical Society. 128: 3198-207. PMID 16522100 DOI: 10.1021/Ja0569757 |
0.766 |
|
| 2006 |
Lewis MA, Long EC. Fluorescent intercalator displacement analyses of DNA binding by the peptide-derived natural products netropsin, actinomycin, and bleomycin. Bioorganic & Medicinal Chemistry. 14: 3481-90. PMID 16439138 DOI: 10.1016/J.Bmc.2006.01.006 |
0.646 |
|
| 2005 |
Goodwin KD, Long EC, Georgiadis MM. A host-guest approach for determining drug-DNA interactions: an example using netropsin. Nucleic Acids Research. 33: 4106-16. PMID 16049022 DOI: 10.1093/Nar/Gki717 |
0.499 |
|
| 2004 |
Fang YY, Ray BD, Claussen CA, Lipkowitz KB, Long EC. Ni(II).Arg-Gly-His-DNA interactions: investigation into the basis for minor-groove binding and recognition. Journal of the American Chemical Society. 126: 5403-12. PMID 15113212 DOI: 10.1021/Ja049875U |
0.762 |
|
| 2003 |
Verma S, Srivatsan SG, Claussen CA, Long EC. DNA strand scission by a Cu(I).adenylated polymeric template: preliminary mechanistic and recycling studies. Bioorganic & Medicinal Chemistry Letters. 13: 2501-4. PMID 12852952 DOI: 10.1016/S0960-894X(03)00501-8 |
0.771 |
|
| 2001 |
Nagane R, Koshigoe T, Chikira M, Long EC. The DNA-bound orientation of Cu(II)·Xaa-Gly-His metallopeptides Journal of Inorganic Biochemistry. 83: 17-23. PMID 11192695 DOI: 10.1016/S0162-0134(00)00129-X |
0.496 |
|
| 2000 |
Ananias DC, Long EC. Highly selective DNA modification by ambient O2-activated Co(II)·Lys-Gly-His metallopeptides [6] Journal of the American Chemical Society. 122: 10460-10461. DOI: 10.1021/Ja002364X |
0.449 |
|
| 1999 |
Claussen CA, Long EC. Nucleic Acid recognition by metal complexes of bleomycin. Chemical Reviews. 99: 2797-816. PMID 11749501 DOI: 10.1021/Cr980449Z |
0.725 |
|
| 1999 |
Huang X, Pieczko ME, Long EC. Combinatorial optimization of the DNA cleaving Ni(II)·Xaa-Xaa-His metallotripeptide domain Biochemistry. 38: 2160-2166. PMID 10026300 DOI: 10.1021/Bi982587O |
0.519 |
|
| 1999 |
Long EC. Ni(II) · Xaa-Xaa-His metallopeptide - DNA/RNA interactions Accounts of Chemical Research. 32: 827-836. DOI: 10.1021/Ar980072J |
0.475 |
|
| 1998 |
Brittain IJ, Huang X, Long EC. Selective recognition and cleavage of RNA loop structures by Ni(II)·Xaa-Gly-His metallopeptides Biochemistry. 37: 12113-12120. PMID 9724523 DOI: 10.1021/Bi9806605 |
0.314 |
|
| 1998 |
Liang Q, Ananias DC, Long EC. Ni(II)·Xaa-Xaa-His induced DNA cleavage: Deoxyribose modification by a common 'activated' intermediate derived from KHSO5, MMPP, or H2O2 Journal of the American Chemical Society. 120: 248-257. DOI: 10.1021/Ja9720218 |
0.456 |
|
| 1997 |
Ananias DC, Long EC. DNA Strand Scission by Dioxygen + Light-Activated Cobalt Metallopeptides. Inorganic Chemistry. 36: 2469-2471. PMID 11669890 |
0.649 |
|
| 1996 |
Long EC, Eason PD, Liang Q. Synthetic metallopeptides as probes of protein-DNA interactions Metal Ions in Biological Systems. 33: 427-452. PMID 8742851 |
0.343 |
|
| 1996 |
Dobbins JR, Murali N, Long EC. Structural redesign and stabilization of the overlapping tandem β-turns of RNA polymerase II International Journal of Peptide and Protein Research. 47: 260-268. PMID 8738651 DOI: 10.1111/J.1399-3011.1996.Tb01354.X |
0.362 |
|
| 1995 |
Liang Q, Eason PD, Long EC. Metallopeptide-DNA interactions: Site-selectivity based on amino acid composition and chirality Journal of the American Chemical Society. 117: 9625-9631. DOI: 10.1021/Ja00143A002 |
0.487 |
|
| 1995 |
Huang X, Long EC. Chemoenzymatic synthesis and incorporation of l-2-quinoxalylalanine into a tandem β-turn peptide motif Bioorganic and Medicinal Chemistry Letters. 5: 1937-1940. DOI: 10.1016/0960-894X(95)00328-Q |
0.391 |
|
| 1994 |
Huang XF, Shullenberger DF, Long EC. Aromatic Stacking and Bending of the DNA Helix by the Individual Repeat Units of the Carboxy-Terminal Domain of RNA Polymerase II Biochemical and Biophysical Research Communications. 198: 712-719. PMID 8297383 DOI: 10.1006/Bbrc.1994.1103 |
0.482 |
|
| 1993 |
Shullenberger DF, Eason PD, Long EC. Design and synthesis of a versatile DNA-cleaving metallopeptide structural domain Journal of the American Chemical Society. 115: 11038-11039. DOI: 10.1021/Ja00076A091 |
0.424 |
|
| 1993 |
Shullenberger DF, Long EC. Design and synthesis of a DNA-cleaving metallopeptide Bioorganic and Medicinal Chemistry Letters. 3: 333-336. DOI: 10.1016/S0960-894X(01)80904-5 |
0.513 |
|
| 1993 |
Hecht SM, Holmes CE, Duff RJ, Morgan MA, Carter BJ, Vroom Ed, Long EC. RNA recognition and cleavage by Fe·bleomycin Journal of Inorganic Biochemistry. 51: 514. DOI: 10.1016/0162-0134(93)85540-O |
0.432 |
|
| 1993 |
Long EC. The DNA helical biopolymer: A template for the binding, assembly, and reactivity of metal ions and complexes Journal of Inorganic and Organometallic Polymers. 3: 3-39. DOI: 10.1007/Bf00696751 |
0.5 |
|
| 1992 |
Kim Y, Long EC, Barton JK, Lieber CM. Imaging of oligonucleotide-metal complexes by scanning tunneling microscopy Langmuir. 8: 496-500. DOI: 10.1021/La00038A031 |
0.442 |
|
| 1992 |
Sitlani A, Long EC, Pyle AM, Barton JK. DNA photocleavage by phenanthrenequinone diimine complexes of rhodium(III): Shape-selective recognition and reaction Journal of the American Chemical Society. 114: 2303-2312. DOI: 10.1021/Ja00033A003 |
0.719 |
|
| 1991 |
Long E, Absalon M, Stubbe J, Barton J. Mechanism of light-induced DNA strand scission by RH(phen)2PHI3+: Cleavage mediated by C3′-H abstraction Journal of Inorganic Biochemistry. 43: 436. DOI: 10.1016/0162-0134(91)84418-9 |
0.372 |
|
| 1990 |
Carter BJ, De Vroom E, Long EC, Van Der Marel GA, Van Boom JH, Hecht SM. Site-specific cleavage of RNA by Fe(II)·bleomycin Proceedings of the National Academy of Sciences of the United States of America. 87: 9373-9377. PMID 1701259 DOI: 10.1073/Pnas.87.23.9373 |
0.431 |
|
| 1990 |
Long EC, Hecht SM, Van der Marel GA, Van Boom JH. Interaction of bleomycin with a methylated DNA oligonucleotide Journal of the American Chemical Society. 112: 5272-5276. DOI: 10.1021/Ja00169A040 |
0.54 |
|
| 1990 |
Long EC, Barton JK. On demonstrating DNA intercalation Accounts of Chemical Research. 23: 271-273. DOI: 10.1021/Ar00177A001 |
0.586 |
|
| 1990 |
Long EC, Hecht SM, Van Der Marel GA, Van Boom JH. Interaction of bleomycin with a methylated DNA oligonucleotide Journal of the American Chemical Society. 112: 5272-5276. |
0.323 |
|
| 1989 |
Pyle AM, Long EC, Barton JK. Shape-selective targeting of DNA by (phenanthrenequinone diimine)rhodium(III) photocleaving agents Journal of the American Chemical Society. 111: 4520-4522. DOI: 10.1021/Ja00194A070 |
0.682 |
|
| 1989 |
Van Atta RB, Long EC, Hecht SM, Van der Marel GA, Van Boom JH. Electrochemical activation of oxygenated iron-bleomycin Journal of the American Chemical Society. 111: 2722-2724. DOI: 10.1021/Ja00189A061 |
0.336 |
|
| 1988 |
Long EC, Hecht SM. Direct comparison of oxygen transfer by iron bleomycin and zinc bleomycin Tetrahedron Letters. 29: 6413-6416. DOI: 10.1016/S0040-4039(00)82360-6 |
0.395 |
|
| 1987 |
Ehrenfeld GM, Shipley JB, Heimbrook DC, Sugiyama H, Long EC, Van Boom JH, Van Der Marel GA, Oppenheimer NJ, Hecht SM. Copper-dependent cleavage of DNA by bleomycin Biochemistry. 26: 931-942. PMID 2436656 DOI: 10.1021/Bi00377A038 |
0.52 |
|
| 1987 |
Heimbrook DC, Carr SA, Mentzer MA, Long EC, Hecht SM. Mechanism of oxygenation of cis-stilbene by iron bleomycin Inorganic Chemistry. 26: 3835-3836. DOI: 10.1021/Ic00270A003 |
0.322 |
|
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