Nicholas J. Cowan - Publications

Affiliations: 
New York University, New York, NY, United States 
Area:
Molecular Biology, Biochemistry

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Tripathy R, Leca I, van Dijk T, Weiss J, van Bon BW, Sergaki MC, Gstrein T, Breuss M, Tian G, Bahi-Buisson N, Paciorkowski AR, Pagnamenta AT, Wenninger-Weinzierl A, Martinez-Reza MF, Landler L, ... ... Cowan NJ, et al. Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations. Neuron. PMID 30449657 DOI: 10.1016/j.neuron.2018.10.044  0.44
2017 Luscan R, Mechaussier S, Paul A, Tian G, Gérard X, Defoort-Dellhemmes S, Loundon N, Audo I, Bonnin S, LeGargasson JF, Dumont J, Goudin N, Garfa-Traoré M, Bras M, Pouliet A, ... ... Cowan NJ, et al. Mutations in TUBB4B Cause a Distinctive Sensorineural Disease. American Journal of Human Genetics. 101: 1006-1012. PMID 29198720 DOI: 10.1016/j.ajhg.2017.10.010  0.44
2016 Edvardson S, Tian G, Cullen H, Vanyai H, Ngo L, Bhat S, Aran A, Daana M, Da'amseh N, Abu-Libdeh B, Cowan NJ, Heng JI, Elpeleg O. Infantile neurodegenerative disorder associated with mutations in TBCD, an essential gene in the tubulin heterodimer assembly pathway. Human Molecular Genetics. 25: 4635-4648. PMID 28158450 DOI: 10.1093/hmg/ddw292  0.44
2016 Breuss MW, Nguyen T, Srivatsan A, Leca I, Tian G, Fritz T, Hansen AH, Musaev D, McEvoy-Venneri J, James KN, Rosti RO, Scott E, Tan U, Kolodner RD, Cowan NJ, et al. Uner Tan Syndrome Caused by a Homozygous TUBB2B Mutation Affecting Microtubule Stability. Human Molecular Genetics. PMID 28013290 DOI: 10.1093/hmg/ddw383  0.44
2016 Tian G, Cristancho AG, Dubbs HA, Liu GT, Cowan NJ, Goldberg EM. A patient with lissencephaly, developmental delay, and infantile spasms, due to de novo heterozygous mutation of KIF2A. Molecular Genetics & Genomic Medicine. 4: 599-603. PMID 27896282 DOI: 10.1002/mgg3.236  0.44
2016 Edvardson S, Tian G, Cullen H, Vanyai H, Ngo L, Bhat S, Aran A, Daana M, Da'amseh N, Abu-Libdeh B, Cowan NJ, Heng J, Elpeleg O. Infantile Neurodegenerative Disorder Associated with Mutations in TBCD, an Essential Gene in the Tubulin Heterodimer Assembly Pathway. Human Molecular Genetics. PMID 27571896 DOI: 10.1093/hmg/ddw292  0.44
2016 Feng R, Yan Z, Li B, Yu M, Sang Q, Tian G, Xu Y, Chen B, Qu R, Sun Z, Sun X, Jin L, He L, Kuang Y, Cowan NJ, et al. Mutations in TUBB8 cause a multiplicity of phenotypes in human oocytes and early embryos. Journal of Medical Genetics. PMID 27273344 DOI: 10.1136/jmedgenet-2016-103891  0.44
2016 Feng R, Sang Q, Kuang Y, Sun X, Yan Z, Zhang S, Shi J, Tian G, Luchniak A, Fukuda Y, Li B, Yu M, Chen J, Xu Y, Guo L, ... ... Cowan NJ, et al. Mutations in TUBB8 and Human Oocyte Meiotic Arrest. The New England Journal of Medicine. 374: 223-232. PMID 26789871 DOI: 10.1056/NEJMoa1510791  0.44
2015 Isrie M, Breuss M, Tian G, Hansen AH, Cristofoli F, Morandell J, Kupchinsky ZA, Sifrim A, Rodriguez-Rodriguez CM, Dapena EP, Doonanco K, Leonard N, Tinsa F, Moortgat S, Ulucan H, ... ... Cowan NJ, et al. Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type. American Journal of Human Genetics. 97: 790-800. PMID 26637975 DOI: 10.1016/j.ajhg.2015.10.014  0.44
2013 Tian G, Cowan NJ. Tubulin-specific chaperones: components of a molecular machine that assembles the α/β heterodimer. Methods in Cell Biology. 115: 155-71. PMID 23973072 DOI: 10.1016/B978-0-12-407757-7.00011-6  0.44
2013 Poirier K, Lebrun N, Broix L, Tian G, Saillour Y, Boscheron C, Parrini E, Valence S, Pierre BS, Oger M, Lacombe D, Geneviève D, Fontana E, Darra F, Cances C, ... ... Cowan NJ, et al. Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly. Nature Genetics. 45: 639-47. PMID 23603762 DOI: 10.1038/ng.2613  0.44
2012 Breuss M, Heng JI, Poirier K, Tian G, Jaglin XH, Qu Z, Braun A, Gstrein T, Ngo L, Haas M, Bahi-Buisson N, Moutard ML, Passemard S, Verloes A, Gressens P, ... ... Cowan NJ, et al. Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Reports. 2: 1554-62. PMID 23246003 DOI: 10.1016/j.celrep.2012.11.017  0.44
2011 Mita P, Savas JN, Djouder N, Yates JR, Ha S, Ruoff R, Schafler ED, Nwachukwu JC, Tanese N, Cowan NJ, Zavadil J, Garabedian MJ, Logan SK. Regulation of androgen receptor-mediated transcription by RPB5 binding protein URI/RMP. Molecular and Cellular Biology. 31: 3639-52. PMID 21730289 DOI: 10.1128/MCB.05429-11  0.44
2010 Tian G, Thomas S, Cowan NJ. Effect of TBCD and its regulatory interactor Arl2 on tubulin and microtubule integrity. Cytoskeleton (Hoboken, N.J.). 67: 706-14. PMID 20740604 DOI: 10.1002/cm.20480  0.44
2010 Tian G, Jaglin XH, Keays DA, Francis F, Chelly J, Cowan NJ. Disease-associated mutations in TUBA1A result in a spectrum of defects in the tubulin folding and heterodimer assembly pathway. Human Molecular Genetics. 19: 3599-613. PMID 20603323 DOI: 10.1093/hmg/ddq276  0.44
2010 Braun A, Breuss M, Salzer MC, Flint J, Cowan NJ, Keays DA. Tuba8 is expressed at low levels in the developing mouse and human brain. American Journal of Human Genetics. 86: 819-22; author reply. PMID 20466094 DOI: 10.1016/j.ajhg.2010.03.019  0.44
2009 Jaglin XH, Poirier K, Saillour Y, Buhler E, Tian G, Bahi-Buisson N, Fallet-Bianco C, Phan-Dinh-Tuy F, Kong XP, Bomont P, Castelnau-Ptakhine L, Odent S, Loget P, Kossorotoff M, Snoeck I, ... ... Cowan NJ, et al. Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria. Nature Genetics. 41: 746-52. PMID 19465910 DOI: 10.1038/ng.380  0.44
2008 Tian G, Kong XP, Jaglin XH, Chelly J, Keays D, Cowan NJ. A pachygyria-causing alpha-tubulin mutation results in inefficient cycling with CCT and a deficient interaction with TBCB. Molecular Biology of the Cell. 19: 1152-61. PMID 18199681 DOI: 10.1091/mbc.E07-09-0861  0.44
2007 Keays DA, Tian G, Poirier K, Huang GJ, Siebold C, Cleak J, Oliver PL, Fray M, Harvey RJ, Molnár Z, Piñon MC, Dear N, Valdar W, Brown SD, Davies KE, ... ... Cowan NJ, et al. Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans. Cell. 128: 45-57. PMID 17218254 DOI: 10.1016/j.cell.2006.12.017  0.44
2006 Tian G, Huang MC, Parvari R, Diaz GA, Cowan NJ. Cryptic out-of-frame translational initiation of TBCE rescues tubulin formation in compound heterozygous HRD. Proceedings of the National Academy of Sciences of the United States of America. 103: 13491-6. PMID 16938882 DOI: 10.1073/pnas.0602798103  0.44
2006 Wang Y, Tian G, Cowan NJ, Cabral F. Mutations affecting beta-tubulin folding and degradation. The Journal of Biological Chemistry. 281: 13628-35. PMID 16554299 DOI: 10.1074/jbc.M513730200  0.44
2005 Bartolini F, Tian G, Piehl M, Cassimeris L, Lewis SA, Cowan NJ. Identification of a novel tubulin-destabilizing protein related to the chaperone cofactor E. Journal of Cell Science. 118: 1197-207. PMID 15728251 DOI: 10.1242/jcs.01719  0.44
2004 Simons CT, Staes A, Rommelaere H, Ampe C, Lewis SA, Cowan NJ. Selective contribution of eukaryotic prefoldin subunits to actin and tubulin binding. The Journal of Biological Chemistry. 279: 4196-203. PMID 14634002 DOI: 10.1074/jbc.M306053200  0.44
2003 Shern JF, Sharer JD, Pallas DC, Bartolini F, Cowan NJ, Reed MS, Pohl J, Kahn RA. Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A. The Journal of Biological Chemistry. 278: 40829-36. PMID 12912990 DOI: 10.1074/jbc.M308678200  0.44
2002 Martín-Benito J, Boskovic J, Gómez-Puertas P, Carrascosa JL, Simons CT, Lewis SA, Bartolini F, Cowan NJ, Valpuesta JM. Structure of eukaryotic prefoldin and of its complexes with unfolded actin and the cytosolic chaperonin CCT. The Embo Journal. 21: 6377-86. PMID 12456645 DOI: 10.1093/emboj/cdf640  0.44
2002 Grayson C, Bartolini F, Chapple JP, Willison KR, Bhamidipati A, Lewis SA, Luthert PJ, Hardcastle AJ, Cowan NJ, Cheetham ME. Localization in the human retina of the X-linked retinitis pigmentosa protein RP2, its homologue cofactor C and the RP2 interacting protein Arl3. Human Molecular Genetics. 11: 3065-74. PMID 12417528  0.44
2002 Lewis SA, Cowan NJ. Bad chaperone. Nature Medicine. 8: 1202-3. PMID 12411941 DOI: 10.1038/nm1102-1202  0.44
2002 Bartolini F, Bhamidipati A, Thomas S, Schwahn U, Lewis SA, Cowan NJ. Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C. The Journal of Biological Chemistry. 277: 14629-34. PMID 11847227 DOI: 10.1074/jbc.M200128200  0.44
2001 Cowan NJ, Lewis SA. Type II chaperonins, prefoldin, and the tubulin-specific chaperones. Advances in Protein Chemistry. 59: 73-104. PMID 11868281 DOI: 10.1016/S0065-3233(01)59003-8  0.44
2000 Lewis SA, Cowan NJ. Purification of prefoldin. Methods in Molecular Biology (Clifton, N.J.). 140: 179-84. PMID 11484487 DOI: 10.1385/1-59259-061-6:179  0.44
2000 Bhamidipati A, Lewis SA, Cowan NJ. ADP ribosylation factor-like protein 2 (Arl2) regulates the interaction of tubulin-folding cofactor D with native tubulin. The Journal of Cell Biology. 149: 1087-96. PMID 10831612 DOI: 10.1083/jcb.149.5.1087  0.44
1999 Cowan NJ, Lewis SA. A chaperone with a hydrophilic surface. Nature Structural Biology. 6: 990-1. PMID 10542082 DOI: 10.1038/14870  0.44
1999 Nielsen KL, McLennan N, Masters M, Cowan NJ. A single-ring mitochondrial chaperonin (Hsp60-Hsp10) can substitute for GroEL-GroES in vivo. Journal of Bacteriology. 181: 5871-5. PMID 10482535  0.44
1999 Tian G, Bhamidipati A, Cowan NJ, Lewis SA. Tubulin folding cofactors as GTPase-activating proteins. GTP hydrolysis and the assembly of the alpha/beta-tubulin heterodimer. The Journal of Biological Chemistry. 274: 24054-8. PMID 10446175 DOI: 10.1074/jbc.274.34.24054  0.44
1999 Hansen WJ, Cowan NJ, Welch WJ. Prefoldin-nascent chain complexes in the folding of cytoskeletal proteins. The Journal of Cell Biology. 145: 265-77. PMID 10209023 DOI: 10.1083/jcb.145.2.265  0.44
1998 Nielsen KL, Cowan NJ. A single ring is sufficient for productive chaperonin-mediated folding in vivo. Molecular Cell. 2: 93-9. PMID 9702195  0.44
1998 Vainberg IE, Lewis SA, Rommelaere H, Ampe C, Vandekerckhove J, Klein HL, Cowan NJ. Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. Cell. 93: 863-73. PMID 9630229 DOI: 10.1016/S0092-8674(00)81446-4  0.44
1998 Cowan NJ. Mammalian cytosolic chaperonin. Methods in Enzymology. 290: 230-41. PMID 9534166 DOI: 10.1016/S0076-6879(98)90022-2  0.44
1997 Lewis SA, Tian G, Cowan NJ. The alpha- and beta-tubulin folding pathways. Trends in Cell Biology. 7: 479-84. PMID 17709011 DOI: 10.1016/S0962-8924(97)01168-9  0.44
1997 Tian G, Lewis SA, Feierbach B, Stearns T, Rommelaere H, Ampe C, Cowan NJ. Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors. The Journal of Cell Biology. 138: 821-32. PMID 9265649 DOI: 10.1083/jcb.138.4.821  0.44
1996 Liedtke W, Edelmann W, Bieri PL, Chiu FC, Cowan NJ, Kucherlapati R, Raine CS. GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination. Neuron. 17: 607-15. PMID 8893019 DOI: 10.1016/S0896-6273(00)80194-4  0.44
1996 Tian G, Huang Y, Rommelaere H, Vandekerckhove J, Ampe C, Cowan NJ. Pathway leading to correctly folded beta-tubulin. Cell. 86: 287-96. PMID 8706133 DOI: 10.1016/S0092-8674(00)80100-2  0.44
1996 Lewis SA, Tian G, Vainberg IE, Cowan NJ. Chaperonin-mediated folding of actin and tubulin. The Journal of Cell Biology. 132: 1-4. PMID 8567715  0.44
1996 Lewis SA, Cowan NJ, Postka S. Progress in Understanding Protein Folding Pharmaceutical Technology. 20: 40-48.  0.44
1995 Tian G, Vainberg IE, Tap WD, Lewis SA, Cowan NJ. Specificity in chaperonin-mediated protein folding. Nature. 375: 250-3. PMID 7746329 DOI: 10.1038/375250a0  0.44
1995 Tian G, Vainberg IE, Tap WD, Lewis SA, Cowan NJ. Quasi-native chaperonin-bound intermediates in facilitated protein folding. The Journal of Biological Chemistry. 270: 23910-3. PMID 7592580 DOI: 10.1074/jbc.270.41.23910  0.44
1994 Gao Y, Melki R, Walden PD, Lewis SA, Ampe C, Rommelaere H, Vandekerckhove J, Cowan NJ. A novel cochaperonin that modulates the ATPase activity of cytoplasmic chaperonin. The Journal of Cell Biology. 125: 989-96. PMID 7910827 DOI: 10.1083/jcb.125.5.989  0.44
1994 Melki R, Cowan NJ. Facilitated folding of actins and tubulins occurs via a nucleotide-dependent interaction between cytoplasmic chaperonin and distinctive folding intermediates. Molecular and Cellular Biology. 14: 2895-904. PMID 7909354  0.44
1993 Walden PD, Cowan NJ. A novel 205-kilodalton testis-specific serine/threonine protein kinase associated with microtubules of the spermatid manchette. Molecular and Cellular Biology. 13: 7625-35. PMID 8246979  0.44
1993 Melki R, Vainberg IE, Chow RL, Cowan NJ. Chaperonin-mediated folding of vertebrate actin-related protein and gamma-tubulin. The Journal of Cell Biology. 122: 1301-10. PMID 8104191  0.44
1993 Wallis KT, Azhar S, Rho MB, Lewis SA, Cowan NJ, Murphy DB. The mechanism of equilibrium binding of microtubule-associated protein 2 to microtubules. Binding is a multi-phasic process and exhibits positive cooperativity. The Journal of Biological Chemistry. 268: 15158-67. PMID 8100819  0.44
1993 Gao Y, Vainberg IE, Chow RL, Cowan NJ. Two cofactors and cytoplasmic chaperonin are required for the folding of alpha- and beta-tubulin. Molecular and Cellular Biology. 13: 2478-85. PMID 8096061  0.44
1993 Rommelaere H, Van Troys M, Gao Y, Melki R, Cowan NJ, Vandekerckhove J, Ampe C. Eukaryotic cytosolic chaperonin contains t-complex polypeptide 1 and seven related subunits. Proceedings of the National Academy of Sciences of the United States of America. 90: 11975-9. PMID 7903455  0.44
1992 Takemura R, Okabe S, Umeyama T, Kanai Y, Cowan NJ, Hirokawa N. Increased microtubule stability and alpha tubulin acetylation in cells transfected with microtubule-associated proteins MAP1B, MAP2 or tau. Journal of Cell Science. 103: 953-64. PMID 1487506  0.44
1992 Chen J, Kanai Y, Cowan NJ, Hirokawa N. Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons. Nature. 360: 674-7. PMID 1465130 DOI: 10.1038/360674a0  0.44
1992 Gao Y, Thomas JO, Chow RL, Lee GH, Cowan NJ. A cytoplasmic chaperonin that catalyzes beta-actin folding. Cell. 69: 1043-50. PMID 1351421 DOI: 10.1016/0092-8674(92)90622-J  0.44
1992 Viitanen PV, Lorimer GH, Seetharam R, Gupta RS, Oppenheim J, Thomas JO, Cowan NJ. Mammalian mitochondrial chaperonin 60 functions as a single toroidal ring. The Journal of Biological Chemistry. 267: 695-8. PMID 1346131  0.44
1992 Zabala JC, Cowan NJ. Tubulin dimer formation via the release of alpha- and beta-tubulin monomers from multimolecular complexes. Cell Motility and the Cytoskeleton. 23: 222-30. PMID 1292878 DOI: 10.1002/cm.970230306  0.44
1991 Sarkar S, Cowan NJ. Intragenic sequences affect the expression of the gene encoding glial fibrillary acidic protein. Journal of Neurochemistry. 57: 675-84. PMID 2072110 DOI: 10.1111/j.1471-4159.1991.tb03799.x  0.44
1991 Sarkar S, Cowan NJ. Regulation of expression of glial filament acidic protein Journal of Cell Science. 100: 97-102.  0.44
1990 Lewis SA, Cowan N. Microtubule bundling. Nature. 345: 674. PMID 2113613 DOI: 10.1038/345674a0  0.44
1989 Gu W, Cowan NJ. Assembly properties of altered beta-tubulin polypeptides containing disrupted autoregulatory domains. Molecular and Cellular Biology. 9: 3418-28. PMID 2677673  0.44
1989 Lewis SA, Ivanov IE, Lee GH, Cowan NJ. Organization of microtubules in dendrites and axons is determined by a short hydrophobic zipper in microtubule-associated proteins MAP2 and tau. Nature. 342: 498-505. PMID 2511449 DOI: 10.1038/342498a0  0.44
1989 Noble M, Lewis SA, Cowan NJ. The microtubule binding domain of microtubule-associated protein MAP1B contains a repeated sequence motif unrelated to that of MAP2 and tau. The Journal of Cell Biology. 109: 3367-76. PMID 2480963 DOI: 10.1083/jcb.109.6.3367  0.44
1988 Aletta JM, Lewis SA, Cowan NJ, Greene LA. Nerve growth factor regulates both the phosphorylation and steady-state levels of microtubule-associated protein 1.2 (MAP1.2). The Journal of Cell Biology. 106: 1573-81. PMID 3372590  0.44
1988 Lewis SA, Cowan NJ. Complex regulation and functional versatility of mammalian alpha- and beta-tubulin isotypes during the differentiation of testis and muscle cells. The Journal of Cell Biology. 106: 2023-33. PMID 3290225  0.44
1988 Gu W, Lewis SA, Cowan NJ. Generation of antisera that discriminate among mammalian alpha-tubulins: introduction of specialized isotypes into cultured cells results in their coassembly without disruption of normal microtubule function. The Journal of Cell Biology. 106: 2011-22. PMID 3290224  0.44
1988 Wang D, Lewis SA, Cowan NJ. Complete sequence of a cDNA encoding mouse MAP2. Nucleic Acids Research. 16: 11369-70. PMID 3205744 DOI: 10.1093/nar/16.23.11369  0.44
1988 Lewis SA, Wang DH, Cowan NJ. Microtubule-associated protein MAP2 shares a microtubule binding motif with tau protein. Science (New York, N.Y.). 242: 936-9. PMID 3142041  0.44
1988 Burgoyne RD, Cambray-Deakin MA, Lewis SA, Sarkar S, Cowan NJ. Differential distribution of beta-tubulin isotypes in cerebellum. The Embo Journal. 7: 2311-9. PMID 2461292  0.44
1988 Cowan NJ, Lewis SA, Gu W, Burgoyne RD. Tubulin isotypes and their interaction with microtubule associated proteins Protoplasma. 145: 106-111. DOI: 10.1007/BF01349346  0.44
1987 Lewis SA, Gu W, Cowan NJ. Free intermingling of mammalian beta-tubulin isotypes among functionally distinct microtubules. Cell. 49: 539-48. PMID 3552250 DOI: 10.1016/0092-8674(87)90456-9  0.44
1987 Hoffman PN, Cleveland DW, Griffin JW, Landes PW, Cowan NJ, Price DL. Neurofilament gene expression: a major determinant of axonal caliber. Proceedings of the National Academy of Sciences of the United States of America. 84: 3472-6. PMID 3472217 DOI: 10.1073/pnas.84.10.3472  0.44
1987 Levy E, Liem RK, D'Eustachio P, Cowan NJ. Structure and evolutionary origin of the gene encoding mouse NF-M, the middle-molecular-mass neurofilament protein. European Journal of Biochemistry / Febs. 166: 71-7. PMID 3036526  0.44
1986 Villasante A, Wang D, Dobner P, Dolph P, Lewis SA, Cowan NJ. Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes. Molecular and Cellular Biology. 6: 2409-19. PMID 3785200  0.44
1986 Lewis SA, Cowan NJ. Anomalous placement of introns in a member of the immediate filament multigene family: An evolutionary conundrum Molecular and Cellular Biology. 6: 1529-1534. PMID 3785173  0.44
1986 Wang D, Villasante A, Lewis SA, Cowan NJ. The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype. The Journal of Cell Biology. 103: 1903-10. PMID 3782288  0.44
1986 Lewis SA, Cowan NJ. Tubulin pseudogenes as markers for hominoid divergence Journal of Molecular Biology. 187: 623-626. PMID 3712438 DOI: 10.1016/0022-2836(86)90340-2  0.44
1986 Lewis SA, Sherline P, Cowan NJ. A cloned cDNA encoding MAP1 detects a single copy gene in mouse and a brain-abundant RNA whose level decreases during development Journal of Cell Biology. 102: 2106-2114. PMID 2423533  0.44
1986 Lewis SA, Villasante A, Sherline P, Cowan NJ. Brain-specific expression of MAP2 detected using a cloned cDNA probe Journal of Cell Biology. 102: 2098-2105. PMID 2423532  0.44
1985 Lewis SA, Gilmartin ME, Hall JL, Cowan NJ. Three expressed sequences within the human beta-tubulin multigene family each define a distinct isotype. Journal of Molecular Biology. 182: 11-20. PMID 3999141 DOI: 10.1016/0022-2836(85)90023-3  0.44
1985 Lewis SA, Cowan NJ. Genetics, evolution, and expression of the 68,000-mol-wt neurofilament protein: Isolation of a cloned cDNA probe Journal of Cell Biology. 100: 843-850. PMID 3919033  0.44
1985 Cowan NJ, Lewis SA, Balcarek JM. Structural implications of a cDNA clone encoding mouse glial fibrillary acidic protein Annals of the New York Academy of Sciences. 575-582. PMID 3866511  0.44
1985 Lewis SA, Lee MGS, Cowan NJ. Five mouse tubulin isotypes and their regulated expression during development Journal of Cell Biology. 101: 852-861. PMID 3839797  0.44
1985 Hall JL, Cowan NJ. Structural features and restricted expression of a human alpha-tubulin gene. Nucleic Acids Research. 13: 207-23. PMID 3839072 DOI: 10.1093/nar/13.1.207  0.44
1985 Balcarek JM, Cowan NJ. Structure of the mouse glial fibrillary acidic protein gene: Implications for the evolution of the intermediate filament multigene family Nucleic Acids Research. 13: 5527-5543. PMID 2994002 DOI: 10.1093/nar/13.15.5527  0.44
1985 Lewis SA, Cowan NJ. Temporal expression of mouse glial fibrillary acidic protein mRNA studied by a rapid in situ hybridization procedure Journal of Neurochemistry. 45: 913-919. PMID 2411859 DOI: 10.1111/j.1471-4159.1985.tb04080.x  0.44
1984 Lewis SA, Balcarek JM, Krek V, Shelanski M, Cowan NJ. Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: Structural conservation of intermediate filaments Proceedings of the National Academy of Sciences of the United States of America. 81: 2743-2746. PMID 6585825  0.44
1984 Lee MGs, Loomis C, Cowan NJ. Sequence of an expressed human β-tubulin gene containing ten Alu family members Nucleic Acids Research. 12: 5823-5836. PMID 6462917 DOI: 10.1093/nar/12.14.5823  0.44
1983 Hall JL, Dudley L, Dobner PR, Lewis SA, Cowan NJ. Identification of two human beta-tubulin isotypes. Molecular and Cellular Biology. 3: 854-62. PMID 6865944  0.44
1983 Cowan NJ, Dudley L. Tubulin isotypes and the multigene tubulin families International Review of Cytology. 147-173. PMID 6689318  0.44
1983 Gwo-Shu Lee M, Lewis SA, Wilde CD, Cowan NJ. Evolutionary history of a multigene family: An expressed human β-tubulin gene and three processed pseudogenes Cell. 33: 477-487. PMID 6688039 DOI: 10.1016/0092-8674(83)90429-4  0.44
1983 Cowan NJ, Dobner PR, Fuchs EV, Cleveland DW. Expression of human α-tubulin genes: Interspecies conservation of 3' untranslated regions Molecular and Cellular Biology. 3: 1738-1745. PMID 6646120  0.44
1982 Wilde CD, Crowther CE, Cripe TP, Lee MGS, Cowan NJ. Evidence that a human β-tubulin pseudogene is derived from its corresponding mRNA Nature. 297: 83-84. PMID 7070533 DOI: 10.1038/297083a0  0.44
1982 Wilde CD, Crowther CE, Cowan NJ. Isolation of a multigene family containing human α-tubulin sequences Journal of Molecular Biology. 155: 533-538. PMID 6283097 DOI: 10.1016/0022-2836(82)90486-7  0.44
1982 Wilde CD, Chow LT, Wefald FC, Cowan NJ. Structure of two human α-tubulin genes Proceedings of the National Academy of Sciences of the United States of America. 79: 96-100. PMID 6275393 DOI: 10.1073/pnas.79.1.96  0.44
1982 Wilde CD, Crowther CE, Cowan NJ. Diverse mechanisms in the generation of human β-tubulin pseudogenes Science. 217: 549-552. PMID 6178164  0.44
1981 Cowan NJ, Wilde CD, Chow LT, Wefald FC. Structural variation among human β-tubulin genes Proceedings of the National Academy of Sciences of the United States of America. 78: 4877-4881. PMID 6946435 DOI: 10.1073/pnas.78.8.4877  0.44
1980 Cleveland DW, Lopata MA, MacDonald RJ, Cowan NJ, Rutter WJ, Kirschner MW. Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes. Cell. 20: 95-105. PMID 6893015 DOI: 10.1016/0092-8674(80)90238-X  0.44
1978 Cleveland DW, Kirschner MW, Cowan NJ. Isolation of separate mRNAs for alpha- and beta-tubulin and characterization of the corresponding in vitro translation products. Cell. 15: 1021-31. PMID 728983 DOI: 10.1016/0092-8674(78)90286-6  0.44
1978 Milstein C, Adetugbo K, Cowan NJ, Kohler G, Secher DS. Expression of antibody genes in tissue culture: structural mutants and hybrid cells. National Cancer Institute Monograph. 321-30. PMID 107455  0.44
1977 Milstein C, Adetugbo K, Cowan NJ, Köhler G, Secher DS, Wilde CD. Somatic cell genetics of antibody-secreting cells: studies of clonal diversification and analysis by cell fusion. Cold Spring Harbor Symposia On Quantitative Biology. 41: 793-803. PMID 408078  0.44
1976 Cowan NJ, Secher DS, Milstein C. Purification and sequence analysis of the mRNA coding for an immunoglobulin heavy chain. European Journal of Biochemistry / Febs. 61: 353-68. PMID 813996  0.44
1974 Cowan NJ, Milstein C. Stability of cytoplasmic ribonucleic acid in a mouse myeloma: estimation of the half-life of the messenger RNA coding for an immunoglobulin light chain. Journal of Molecular Biology. 82: 469-81. PMID 4817791 DOI: 10.1016/0022-2836(74)90242-3  0.44
1974 Cowan NJ, Secher DS, Milstein C. Intracellular immunoglobulin chain synthesis in non-secreting variants of a mouse myeloma: detection of inactive light-chain messenger RNA. Journal of Molecular Biology. 90: 691-701. PMID 4449137 DOI: 10.1016/0022-2836(74)90533-6  0.44
1973 Cowan NJ, Secher DS, Cotton RG, Milstein C. The secretion of a sialic acid-free immunoglobulin. Febs Letters. 30: 343-6. PMID 4735599 DOI: 10.1016/0014-5793(73)80684-2  0.44
1973 Cowan NJ, Milstein C. The translation in vitro of mRNA for immunoglobulin heavy chains. European Journal of Biochemistry / Febs. 36: 1-7. PMID 4732916 DOI: 10.1111/j.1432-1033.1973.tb02877.x  0.44
1973 Brownlee GG, Cartwright EM, Cowan NJ, Jarvis JM, Milstein C. Purification and sequence of messenger RNA for immunoglobulin light chains. Nature: New Biology. 244: 236-40. PMID 4516600 DOI: 10.1038/newbio244236a0  0.44
1972 Cowan NJ, Robinson GB. The sequence of addition of terminal sugars to an immunoglobulin A myeloma protein Biochemical Journal. 126: 751-754. PMID 5075277  0.44
1972 Cowan NJ, Milstein C. Automatic monitoring of biochemical parameters in tissue culture. Studies on synchronously growing mouse myeloma cells. The Biochemical Journal. 128: 445-54. PMID 4673519  0.44
1970 Cowan NJ, Robinson GB. The ribosomal incorporation of hexosamine into glycoprotein in a mouse myeloma Febs Letters. 8: 6-8. DOI: 10.1016/0014-5793(70)80211-3  0.44
1969 Cowan NJ, Robinson GB. The subcellular acquisition of carbohydrates by glycoproteins Biochemical Journal. 115. PMID 5360710  0.44
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