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Iris J. Edwards - Publications

Affiliations: 
Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
Pathology, Biochemistry
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Gu Z, Wu J, Wang S, Suburu J, Chen H, Thomas MJ, Shi L, Edwards IJ, Berquin IM, Chen YQ. Polyunsaturated fatty acids affect the localization and signaling of PIP3/AKT in prostate cancer cells. Carcinogenesis. 34: 1968-75. PMID 23633519 DOI: 10.1093/Carcin/Bgt147  0.304
2013 Hu Y, Sun H, O'Flaherty JT, Edwards IJ. 15-Lipoxygenase-1-mediated metabolism of docosahexaenoic acid is required for syndecan-1 signaling and apoptosis in prostate cancer cells. Carcinogenesis. 34: 176-82. PMID 23066085 DOI: 10.1093/Carcin/Bgs324  0.31
2012 O'Flaherty JT, Hu Y, Wooten RE, Horita DA, Samuel MP, Thomas MJ, Sun H, Edwards IJ. 15-lipoxygenase metabolites of docosahexaenoic acid inhibit prostate cancer cell proliferation and survival. Plos One. 7: e45480. PMID 23029040 DOI: 10.1371/Journal.Pone.0045480  0.304
2010 Hu Y, Sun H, Owens RT, Gu Z, Wu J, Chen YQ, O'Flaherty JT, Edwards IJ. Syndecan-1-dependent suppression of PDK1/Akt/bad signaling by docosahexaenoic acid induces apoptosis in prostate cancer. Neoplasia (New York, N.Y.). 12: 826-36. PMID 20927321 DOI: 10.1593/Neo.10586  0.324
2008 Edwards IJ, O'Flaherty JT. Omega-3 Fatty Acids and PPARgamma in Cancer. Ppar Research. 2008: 358052. PMID 18769551 DOI: 10.1155/2008/358052  0.329
2008 Berquin IM, Edwards IJ, Chen YQ. Multi-targeted therapy of cancer by omega-3 fatty acids. Cancer Letters. 269: 363-77. PMID 18479809 DOI: 10.1016/J.Canlet.2008.03.044  0.304
2008 Edwards IJ, Sun H, Hu Y, Berquin IM, O'Flaherty JT, Cline JM, Rudel LL, Chen YQ. In vivo and in vitro regulation of syndecan 1 in prostate cells by n-3 polyunsaturated fatty acids. The Journal of Biological Chemistry. 283: 18441-9. PMID 18450755 DOI: 10.1074/Jbc.M802107200  0.336
2008 Sun H, Berquin IM, Owens RT, O'Flaherty JT, Edwards IJ. Peroxisome proliferator-activated receptor gamma-mediated up-regulation of syndecan-1 by n-3 fatty acids promotes apoptosis of human breast cancer cells. Cancer Research. 68: 2912-9. PMID 18413760 DOI: 10.1158/0008-5472.Can-07-2305  0.314
2005 Sun H, Berquin IM, Edwards IJ. Omega-3 polyunsaturated fatty acids regulate syndecan-1 expression in human breast cancer cells. Cancer Research. 65: 4442-7. PMID 15899837 DOI: 10.1158/0008-5472.Can-04-4200  0.355
2004 Edwards IJ, Berquin IM, Sun H, O'flaherty JT, Daniel LW, Thomas MJ, Rudel LL, Wykle RL, Chen YQ. Differential effects of delivery of omega-3 fatty acids to human cancer cells by low-density lipoproteins versus albumin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8275-83. PMID 15623603 DOI: 10.1158/1078-0432.Ccr-04-1357  0.332
2004 Edwards IJ, Wagner JD, Vogl-Willis CA, Litwak KN, Cefalu WT. Arterial heparan sulfate is negatively associated with hyperglycemia and atherosclerosis in diabetic monkeys. Cardiovascular Diabetology. 3: 6. PMID 15117408 DOI: 10.1186/1475-2840-3-6  0.622
2004 Vogl-Willis CA, Edwards IJ. High-glucose-induced structural changes in the heparan sulfate proteoglycan, perlecan, of cultured human aortic endothelial cells. Biochimica Et Biophysica Acta. 1672: 36-45. PMID 15056491 DOI: 10.1016/J.Bbagen.2004.02.005  0.654
2004 Vogl-Willis CA, Edwards IJ. High glucose-induced alterations in subendothelial matrix perlecan leads to increased monocyte binding. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 858-63. PMID 15031130 DOI: 10.1161/01.Atv.0000126375.60073.74  0.645
2002 Edwards IJ, Terry JG, Bell-Farrow AD, Cefalu WT. Improved glucose control decreases the interaction of plasma low-density lipoproteins with arterial proteoglycans. Metabolism: Clinical and Experimental. 51: 1223-9. PMID 12370838 DOI: 10.1053/Meta.2002.35177  0.483
2001 Edwards IJ, Rudel LL, Terry JG, Kemnitz JW, Weindruch R, Zaccaro DJ, Cefalu WT. Caloric restriction lowers plasma lipoprotein (a) in male but not female rhesus monkeys. Experimental Gerontology. 36: 1413-8. PMID 11602214 DOI: 10.1016/S0531-5565(01)00107-3  0.303
1999 Cefalu WT, Wagner JD, Bell-Farrow AD, Edwards IJ, Terry JG, Weindruch R, Kemnitz JW. Influence of caloric restriction on the development of atherosclerosis in nonhuman primates: progress to date. Toxicological Sciences : An Official Journal of the Society of Toxicology. 52: 49-55. PMID 10630590 DOI: 10.1093/Toxsci/52.2.49  0.374
1999 Edwards IJ, Wagner JD, Litwak KN, Rudel LL, Cefalu WT. Glycation of plasma low density lipoproteins increases interaction with arterial proteoglycans. Diabetes Research and Clinical Practice. 46: 9-18. PMID 10580610 DOI: 10.1016/S0168-8227(99)00074-1  0.477
1998 Edwards IJ, Rudel LL, Terry JG, Kemnitz JW, Weindruch R, Cefalu WT. Caloric restriction in rhesus monkeys reduces low density lipoprotein interaction with arterial proteoglycans. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 53: B443-8. PMID 9823741 DOI: 10.1093/Gerona/53A.6.B443  0.364
1997 Manning JM, Edwards IJ, Wagner WD, Wagner JD, Adams MR, Parks JS. Effects of contraceptive estrogen and progestin on the atherogenic potential of plasma LDLs in cynomolgus monkeys. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 1216-23. PMID 9261249 DOI: 10.1161/01.Atv.17.7.1216  0.332
1996 Manning JM, Campos G, Edwards IJ, Wagner WD, Wagner JD, Adams MR, Parks JS. Effects of hormone replacement modalities on low density lipoprotein composition and distribution in ovariectomized cynomolgus monkeys. Atherosclerosis. 121: 217-29. PMID 9125296 DOI: 10.1016/0021-9150(95)05723-4  0.311
1995 Edwards IJ, Xu H, Obunike JC, Goldberg IJ, Wagner WD. Differentiated macrophages synthesize a heparan sulfate proteoglycan and an oversulfated chondroitin sulfate proteoglycan that bind lipoprotein lipase. Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 400-9. PMID 7749850 DOI: 10.1161/01.Atv.15.3.400  0.364
1994 Manning JM, Gebre AK, Edwards IJ, Wagner WD, Rudel LL, Parks JS. Dietary polyunsaturated fat decreases interaction between low density lipoproteins and arterial proteoglycans. Lipids. 29: 635-41. PMID 7815898 DOI: 10.1007/Bf02536098  0.365
1991 Edwards IJ, Gebre AK, Wagner WD, Parks JS. Reduced proteoglycan binding of low density lipoproteins from monkeys (Macaca fascicularis) fed a fish oil versus lard diet. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology / American Heart Association. 11: 1778-85. PMID 1931879 DOI: 10.1161/01.Atv.11.6.1778  0.308
1989 Wagner WD, Edwards IJ, St Clair RW, Barakat H. Low density lipoprotein interaction with artery derived proteoglycan: the influence of LDL particle size and the relationship to atherosclerosis susceptibility. Atherosclerosis. 75: 49-59. PMID 2930613 DOI: 10.1016/0021-9150(89)90206-2  0.369
1987 Sekhara Rao BP, Wagner WD, Hutchins PM, Rowe HA, Edwards IJ. Spontaneous and diet-aggravated atherosclerosis in White Carneau pigeons genetically selected for discordant blood pressure. Atherosclerosis. 65: 29-35. PMID 3606732 DOI: 10.1016/0021-9150(87)90005-0  0.324
1987 Steele RH, Wagner WD, Rowe HA, Edwards IJ. Artery wall derived proteoglycan-plasma lipoprotein interaction: lipoprotein binding properties of extracted proteoglycans. Atherosclerosis. 65: 51-62. PMID 3111491 DOI: 10.1016/0021-9150(87)90007-4  0.384
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