Zhen-Qiang Pan - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Molecular Biology, Biochemistry

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wu K, Pan ZQ. A Novel Strategy to Track Lysine-48 Ubiquitination by Fluorescence Resonance Energy Transfer. Methods in Molecular Biology (Clifton, N.J.). 2267: 91-102. PMID 33786787 DOI: 10.1007/978-1-0716-1217-0_7  0.72
2021 Wu K, Huynh KQ, Lu I, Moustakim M, Miao H, Yu C, Haeusgen MJ, Hopkins BD, Huang L, Zheng N, Sanchez R, DeVita RJ, Pan ZQ. Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33602808 DOI: 10.1073/pnas.2007328118  0.72
2020 Wu K, Ching K, Chong RA, Pan ZQ. A new Förster resonance energy transfer-based platform to track substrate ubiquitination by fluorescence. The Journal of Biological Chemistry. PMID 33361156 DOI: 10.1074/jbc.RA120.016858  0.72
2020 Li Z, Wang D, Lu J, Huang B, Wang Y, Dong M, Fan D, Li H, Gao Y, Hou P, Li M, Liu H, Pan ZQ, Zheng J, Bai J. Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis. Cell Death and Differentiation. PMID 32895488 DOI: 10.1038/S41418-020-00615-9  0.52
2020 Yu Q, Hu Z, Shen Y, Jiang Y, Pan P, Hou T, Pan ZQ, Huang J, Sun Y. Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexes. Neoplasia (New York, N.Y.). 22: 179-191. PMID 32145688 DOI: 10.1016/J.Neo.2020.02.003  0.48
2020 Zhang J, Zhao R, Yu C, Bryant CLN, Wu K, Liu Z, Ding Y, Zhao Y, Xue B, Pan ZQ, Li C, Huang L, Fang L. IKK-mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5. Journal of Proteome Research. PMID 31950832 DOI: 10.1021/Acs.Jproteome.9B00626  0.72
2019 Bai J, Wu K, Cao MH, Yang Y, Pan Y, Liu H, He Y, Itahana Y, Huang L, Zheng JN, Pan ZQ. SCF targets HDM2 for degradation and modulates breast cancer cell invasion and metastasis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31138683 DOI: 10.1073/Pnas.1820990116  0.72
2017 Zhou H, Lu J, Liu L, Bernard D, Yang CY, Fernandez-Salas E, Chinnaswamy K, Layton S, Stuckey J, Yu Q, Zhou W, Pan Z, Sun Y, Wang S. A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation. Nature Communications. 8: 1150. PMID 29074978 DOI: 10.1038/S41467-017-01243-7  0.48
2016 Zhou W, Xu J, Li H, Xu M, Chen ZJ, Wei W, Pan ZQ, Sun Y. Neddylation E2 UBE2F promotes the survival of lung cancer cells by activating CRL5 to degrade NOXA via the K11 linkage. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27591266 DOI: 10.1158/1078-0432.Ccr-16-1585  0.48
2016 Wu K, Chong RA, Yu Q, Bai J, Spratt DE, Ching K, Lee C, Miao H, Tappin I, Hurwitz J, Zheng N, Shaw GS, Sun Y, Felsenfeld DP, Sanchez R, ... ... Pan ZQ, et al. Suramin inhibits cullin-RING E3 ubiquitin ligases. Proceedings of the National Academy of Sciences of the United States of America. PMID 27001857 DOI: 10.1073/Pnas.1601089113  0.72
2015 Li HL, Han L, Chen HR, Meng F, Liu QH, Pan ZQ, Bai J, Zheng JN. PinX1 serves as a potential prognostic indicator for clear cell renal cell carcinoma and inhibits its invasion and metastasis by suppressing MMP-2 via NF-κB-dependent transcription. Oncotarget. PMID 26033551  0.44
2015 Sun C, Li HL, Chen HR, Shi ML, Liu QH, Pan ZQ, Bai J, Zheng JN. Decreased expression of CHIP leads to increased angiogenesis via VEGF-VEGFR2 pathway and poor prognosis in human renal cell carcinoma. Scientific Reports. 5: 9774. PMID 26021863 DOI: 10.1038/Srep09774  0.44
2015 Shi M, Cao M, Song J, Liu Q, Li H, Meng F, Pan Z, Bai J, Zheng J. PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway. Molecular Cancer. 14: 66. PMID 25888829 DOI: 10.1186/S12943-015-0332-2  0.52
2015 Chong RA, Wu K, Kovacev J, Pan ZQ. Generation of a proteolytic signal: E3/E2-mediated polyubiquitination of IκBα. Methods in Molecular Biology (Clifton, N.J.). 1280: 339-54. PMID 25736759 DOI: 10.1007/978-1-4939-2422-6_20  0.72
2015 Pan Z, Liu H. Numerical study of typhoon-induced storm surge in the Yangtze Estuary of China using a coupled 3D model Procedia Engineering. 116: 849-854. DOI: 10.1016/j.proeng.2015.08.373  0.32
2015 Pan Z, Wu Y. Building and testing network security situational awareness model based on Bayesian method Iet Conference Publications. 2015.  0.32
2014 Hartmann T, Xu X, Kronast M, Muehlich S, Meyer K, Zimmermann W, Hurwitz J, Pan ZQ, Engelhardt S, Sarikas A. Inhibition of Cullin-RING E3 ubiquitin ligase 7 by simian virus 40 large T antigen. Proceedings of the National Academy of Sciences of the United States of America. 111: 3371-6. PMID 24550499 DOI: 10.1073/Pnas.1401556111  0.72
2014 Kovacev J, Wu K, Spratt DE, Chong RA, Lee C, Nayak J, Shaw GS, Pan ZQ. A snapshot of ubiquitin chain elongation: lysine 48-tetra-ubiquitin slows down ubiquitination. The Journal of Biological Chemistry. 289: 7068-81. PMID 24464578 DOI: 10.1074/Jbc.M113.530576  0.72
2014 Pan Z, Chen YY, Wu X, Trisal V, Wilczynski SP, Weiss LM, Chu PG, Wu H. Merkel cell carcinoma of lymph node with unknown primary has a significantly lower association with Merkel cell polyomavirus than its cutaneous counterpart. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 27: 1182-92. PMID 24406862 DOI: 10.1038/Modpathol.2013.250  0.36
2014 Scheufele F, Wolf B, Kruse M, Hartmann T, Lempart J, Muehlich S, Pfeiffer AF, Field LJ, Charron MJ, Pan ZQ, Engelhardt S, Sarikas A. Evidence for a regulatory role of Cullin-RING E3 ubiquitin ligase 7 in insulin signaling. Cellular Signalling. 26: 233-9. PMID 24219910 DOI: 10.1016/J.Cellsig.2013.11.005  0.72
2013 Bai J, Mei P, Zhang C, Chen F, Li C, Pan Z, Liu H, Zheng J. BRG1 is a prognostic marker and potential therapeutic target in human breast cancer. Plos One. 8: e59772. PMID 23533649 DOI: 10.1371/Journal.Pone.0059772  0.52
2013 Chen F, Bai J, Li W, Mei P, Liu H, Li L, Pan Z, Wu Y, Zheng J. RUNX3 suppresses migration, invasion and angiogenesis of human renal cell carcinoma. Plos One. 8: e56241. PMID 23457532 DOI: 10.1371/Journal.Pone.0056241  0.52
2013 Zheng W, Feng X, Qiu L, Pan Z, Wang R, Lin S, Hou D, Jin L, Li Y. Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes Diabetologia. 56: 401-411. PMID 23178929 DOI: 10.1007/S00125-012-2777-9  0.4
2012 Xu X, Keshwani M, Meyer K, Sarikas A, Taylor S, Pan ZQ. Identification of the degradation determinants of insulin receptor substrate 1 for signaling cullin-RING E3 ubiquitin ligase 7-mediated ubiquitination. The Journal of Biological Chemistry. 287: 40758-66. PMID 23045529 DOI: 10.1074/Jbc.M112.405209  0.68
2012 Spratt DE, Wu K, Kovacev J, Pan ZQ, Shaw GS. Selective recruitment of an E2~ubiquitin complex by an E3 ubiquitin ligase. The Journal of Biological Chemistry. 287: 17374-85. PMID 22433864 DOI: 10.1074/Jbc.M112.353748  0.72
2011 Wu K, Yan H, Fang L, Wang X, Pfleger C, Jiang X, Huang L, Pan ZQ. Mono-ubiquitination drives nuclear export of the human DCN1-like protein hDCNL1. The Journal of Biological Chemistry. 286: 34060-70. PMID 21813641 DOI: 10.1074/Jbc.M111.273045  0.72
2011 Sarikas A, Hartmann T, Pan ZQ. The cullin protein family. Genome Biology. 12: 220. PMID 21554755 DOI: 10.1186/Gb-2011-12-4-220  0.68
2011 Pan Z, Li H. Circuit design for a neuron based on FPAA 2011 International Conference On Electronics, Communications and Control, Icecc 2011 - Proceedings. 2584-2587. DOI: 10.1109/ICECC.2011.6067894  0.44
2011 Liu H, Pan Z. Hierarchical case based reasoning method for assembly sequence planning of automobile body Zhongguo Jixie Gongcheng/China Mechanical Engineering. 22: 1059-1066.  0.32
2010 Tan M, Zhu Y, Kovacev J, Zhao Y, Pan ZQ, Spitz DR, Sun Y. Disruption of Sag/Rbx2/Roc2 induces radiosensitization by increasing ROS levels and blocking NF-kappaB activation in mouse embryonic stem cells. Free Radical Biology & Medicine. 49: 976-83. PMID 20638939 DOI: 10.1016/J.Freeradbiomed.2010.05.030  0.72
2010 Choi YS, Wu K, Jeong K, Lee D, Jeon YH, Choi BS, Pan ZQ, Ryu KS, Cheong C. The human Cdc34 carboxyl terminus contains a non-covalent ubiquitin binding activity that contributes to SCF-dependent ubiquitination. The Journal of Biological Chemistry. 285: 17754-62. PMID 20353940 DOI: 10.1074/Jbc.M109.090621  0.72
2010 Wu K, Kovacev J, Pan ZQ. Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate. Molecular Cell. 37: 784-96. PMID 20347421 DOI: 10.1016/J.Molcel.2010.02.025  0.72
2008 Sarikas A, Xu X, Field LJ, Pan ZQ. The cullin7 E3 ubiquitin ligase: a novel player in growth control. Cell Cycle (Georgetown, Tex.). 7: 3154-61. PMID 18927510 DOI: 10.4161/Cc.7.20.6922  0.68
2008 Fang L, Wang X, Yamoah K, Chen PL, Pan ZQ, Huang L. Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry. Journal of Proteome Research. 7: 4914-25. PMID 18850735 DOI: 10.1021/Pr800574C  0.72
2008 Yamoah K, Oashi T, Sarikas A, Gazdoiu S, Osman R, Pan ZQ. Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail. Proceedings of the National Academy of Sciences of the United States of America. 105: 12230-5. PMID 18723677 DOI: 10.1073/Pnas.0806155105  0.72
2008 Xu X, Sarikas A, Dias-Santagata DC, Dolios G, Lafontant PJ, Tsai SC, Zhu W, Nakajima H, Nakajima HO, Field LJ, Wang R, Pan ZQ. The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation. Molecular Cell. 30: 403-14. PMID 18498745 DOI: 10.1016/J.Molcel.2008.03.009  0.68
2008 Jones J, Wu K, Yang Y, Guerrero C, Nillegoda N, Pan ZQ, Huang L. A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins. Journal of Proteome Research. 7: 1274-87. PMID 18247557 DOI: 10.1021/pr700749v  0.72
2007 Kumar A, Wu H, Collier-Hyams LS, Hansen JM, Li T, Yamoah K, Pan ZQ, Jones DP, Neish AS. Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species. The Embo Journal. 26: 4457-66. PMID 17914462 DOI: 10.1038/Sj.Emboj.7601867  0.72
2007 Umanskaya K, Radke S, Chander H, Monardo R, Xu X, Pan ZQ, O'Connell MJ, Germain D. Skp2B stimulates mammary gland development by inhibiting REA, the repressor of the estrogen receptor. Molecular and Cellular Biology. 27: 7615-22. PMID 17785450 DOI: 10.1128/Mcb.01239-07  0.72
2007 Gazdoiu S, Yamoah K, Wu K, Pan ZQ. Human Cdc34 employs distinct sites to coordinate attachment of ubiquitin to a substrate and assembly of polyubiquitin chains. Molecular and Cellular Biology. 27: 7041-52. PMID 17698585 DOI: 10.1128/Mcb.00812-07  0.72
2007 Poyurovsky MV, Priest C, Kentsis A, Borden KLB, Pan ZQ, Pavletich N, Prives C. The Mdm2 RING domain C-terminus is required for supramolecular assembly and ubiquitin ligase activity Embo Journal. 26: 90-101. PMID 17170710 DOI: 10.1038/Sj.Emboj.7601465  0.72
2007 Nakayama K, Gazdoiu S, Abraham R, Pan ZQ, Ronai Z. Hypoxia-induced assembly of prolyl hydroxylase PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2. The Biochemical Journal. 401: 217-26. PMID 16958618 DOI: 10.1042/Bj20061135  0.72
2005 Yamoah K, Wu K, Pan ZQ. In vitro cleavage of Nedd8 from cullin 1 by COP9 signalosome and deneddylase 1. Methods in Enzymology. 398: 509-22. PMID 16275355 DOI: 10.1016/S0076-6879(05)98042-7  0.72
2005 Gazdoiu S, Yamoah K, Wu K, Escalante CR, Tappin I, Bermudez V, Aggarwal AK, Hurwitz J, Pan ZQ. Proximity-induced activation of human Cdc34 through heterologous dimerization. Proceedings of the National Academy of Sciences of the United States of America. 102: 15053-8. PMID 16210246 DOI: 10.1073/Pnas.0507646102  0.72
2005 Huber C, Dias-Santagata D, Glaser A, O'Sullivan J, Brauner R, Wu K, Xu X, Pearce K, Wang R, Uzielli ML, Dagoneau N, Chemaitilly W, Superti-Furga A, Dos Santos H, Mégarbané A, ... ... Pan ZQ, et al. Identification of mutations in CUL7 in 3-M syndrome. Nature Genetics. 37: 1119-24. PMID 16142236 DOI: 10.1038/Ng1628  0.72
2005 Pan ZQ. Teaching resources. Nuclear transactivators and repressors. Science's Stke : Signal Transduction Knowledge Environment. 2005: tr18. PMID 15972701 DOI: 10.1126/stke.2892005tr18  0.72
2005 Miller F, Kentsis A, Osman R, Pan ZQ. Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL·hypoxia-inducible transcription factor-1α complex Journal of Biological Chemistry. 280: 7985-7996. PMID 15611064 DOI: 10.1074/Jbc.M413160200  0.72
2005 Reverter D, Wu K, Erdene TG, Pan ZQ, Wilkinson KD, Lima CD. Structure of a complex between Nedd8 and the Ulp/Senp protease family member Den1. Journal of Molecular Biology. 345: 141-51. PMID 15567417 DOI: 10.1016/J.Jmb.2004.10.022  0.72
2004 Pan ZQ, Kentsis A, Dias DC, Yamoah K, Wu K. Nedd8 on cullin: Building an expressway to protein destruction Oncogene. 23: 1985-1997. PMID 15021886 DOI: 10.1038/Sj.Onc.1207414  0.72
2004 Li Y, Gazdoiu S, Pan ZQ, Fuchs SY. Stability of homologue of Slimb F-box protein is regulated by availability of its substrate. The Journal of Biological Chemistry. 279: 11074-80. PMID 14707120 DOI: 10.1074/Jbc.M312301200  0.72
2003 Wu K, Yamoah K, Dolios G, Gan-Erdene T, Tan P, Chen A, Lee CG, Wei N, Wilkinson KD, Wang R, Pan ZQ. DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1. The Journal of Biological Chemistry. 278: 28882-91. PMID 12759363 DOI: 10.1074/Jbc.M302888200  0.72
2003 Gan-Erdene T, Nagamalleswari K, Yin L, Wu K, Pan ZQ, Wilkinson KD. Identification and characterization of DEN1, a deneddylase of the ULP family. The Journal of Biological Chemistry. 278: 28892-900. PMID 12759362 DOI: 10.1074/Jbc.M302890200  0.72
2003 Jiang Y, Pan Z. Graphics Web publishing in electric power management information system Dianli Xitong Zidonghua/Automation of Electric Power Systems. 27: 61-64.  0.44
2002 Dias DC, Dolios G, Wang R, Pan ZQ. CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex. Proceedings of the National Academy of Sciences of the United States of America. 99: 16601-6. PMID 12481031 DOI: 10.1073/Pnas.252646399  0.72
2002 Macip S, Igarashi M, Fang L, Chen A, Pan ZQ, Lee SW, Aaronson SA. Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence. The Embo Journal. 21: 2180-8. PMID 11980715 DOI: 10.1093/Emboj/21.9.2180  0.44
2002 Wu K, Chen A, Tan P, Pan ZQ. The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34. The Journal of Biological Chemistry. 277: 516-27. PMID 11675391 DOI: 10.1074/Jbc.M108008200  0.72
2001 Kentsis A, Dwyer EC, Perez JM, Sharma M, Chen A, Pan ZQ, Borden KLB. The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E Journal of Molecular Biology. 312: 609-623. PMID 11575918 DOI: 10.1006/Jmbi.2001.5003  0.32
2001 Pan Z, Li H. Application of image manipulation for cavitation analyzing Chinese Journal of Mechanical Engineering (English Edition). 14: 271-274.  0.44
2000 Wu K, Chen A, Pan ZQ. Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization. The Journal of Biological Chemistry. 275: 32317-24. PMID 10921923 DOI: 10.1074/Jbc.M004847200  0.72
2000 Chen A, Wu K, Fuchs SY, Tan P, Gomez C, Pan ZQ. The conserved RING-H2 finger of ROC1 is required for ubiquitin ligation. The Journal of Biological Chemistry. 275: 15432-9. PMID 10748083 DOI: 10.1074/Jbc.M907300199  0.72
2000 Wu K, Fuchs SY, Chen A, Tan P, Gomez C, Ronai Z, Pan ZQ. The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation. Molecular and Cellular Biology. 20: 1382-93. PMID 10648623 DOI: 10.1128/Mcb.20.4.1382-1393.2000  0.72
1999 Fuchs SY, Chen A, Xiong Y, Pan ZQ, Ronai Z. HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin. Oncogene. 18: 2039-46. PMID 10321728 DOI: 10.1038/Sj.Onc.1202760  0.44
1999 Tan P, Fuchs SY, Chen A, Wu K, Gomez C, Ronai Z, Pan ZQ. Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha. Molecular Cell. 3: 527-33. PMID 10230406 DOI: 10.1016/S1097-2765(00)80481-5  0.72
1996 Li Y, Pan Z. Structure and thermal properties of vinylidene chloride/acrylics copolymers Journal of Applied Polymer Science. 61: 2397-2402.  0.4
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