| Year |
Citation |
Score |
| 2021 |
Arbel Rubinstein T, Reuveni I, Hesin A, Klein-Goldberg A, Olauson H, Larsson TE, Abraham CR, Zeldich E, Bosch A, Chillón M, Hollander KS, Shabtay-Orbach A, Vainer GW, Wolf I, Rubinek T. A Transgenic Model Reveals the Role of Klotho in Pancreatic Cancer Development and Paves the Way for New Klotho-Based Therapy. Cancers. 13. PMID 34944918 DOI: 10.3390/cancers13246297 |
0.704 |
|
| 2021 |
Hinman JD, Ngo KJ, Kim D, Chen C, Abraham CR, Ghanbari M, Ikram MA, Kushner SA, Kawaguchi R, Coppola G, Goth K, Bellusci S, Hernandez I, Kosik KS, Fogel BL. miR-142-3p Regulates Cortical Oligodendrocyte Gene Co-expression Networks Associated with Tauopathy. Human Molecular Genetics. PMID 33555315 DOI: 10.1093/hmg/ddaa252 |
0.773 |
|
| 2020 |
Wolf EJ, Chen CD, Zhao X, Zhou Z, Morrison FG, Daskalakis NP, Stone A, Schichman S, Grenier JG, Fein-Schaffer D, Huber BR, Abraham CR, Miller MW, Logue MW. Klotho, PTSD, and advanced epigenetic age in cortical tissue. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33096543 DOI: 10.1038/s41386-020-00884-5 |
0.681 |
|
| 2020 |
Chen CD, Rudy MA, Zeldich E, Abraham CR. A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32347987 DOI: 10.1096/Fj.202000171R |
0.802 |
|
| 2020 |
Chen CD, Li Y, Chen AK, Rudy MA, Nasse JS, Zeldich E, Polanco TJ, Abraham CR. Identification of the cleavage sites leading to the shed forms of human and mouse anti-aging and cognition-enhancing protein Klotho. Plos One. 15: e0226382. PMID 31929539 DOI: 10.1371/Journal.Pone.0226382 |
0.797 |
|
| 2019 |
Delitsikou V, Jarad G, Rajaram RD, Ino F, Rutkowski JM, Chen CD, Santos CXC, Scherer PE, Abraham CR, Shah AM, Feraille E, Miner JH, de Seigneux S. Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31907991 DOI: 10.1096/Fj.201900893R |
0.71 |
|
| 2019 |
Zeldich E, Chen CD, Boden E, Howat B, Nasse JS, Zeldich D, Lambert AG, Yuste A, Cherry JD, Mathias RM, Ma Q, Lau NC, McKee AC, Hatzipetros T, Abraham CR. Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1) Mouse Model of ALS. Journal of Molecular Neuroscience : Mn. PMID 31250273 DOI: 10.1007/S12031-019-01356-2 |
0.792 |
|
| 2019 |
McGrath ER, Himali JJ, Levy D, Conner SC, Pase MP, Abraham CR, Courchesne P, Satizabal CL, Vasan RS, Beiser AS, Seshadri S. Circulating fibroblast growth factor 23 levels and incident dementia: The Framingham heart study. Plos One. 14: e0213321. PMID 30830941 DOI: 10.1371/Journal.Pone.0213321 |
0.303 |
|
| 2019 |
Chen CD, Zeldich E, Khodr C, Camara K, Tung TY, Lauder EC, Mullen P, Polanco TJ, Liu YY, Zeldich D, Xia W, Van Nostrand WE, Brown LE, Porco JA, Abraham CR. Small Molecule Amyloid-β Protein Precursor Processing Modulators Lower Amyloid-β Peptide Levels via cKit Signaling. Journal of Alzheimer's Disease : Jad. 67: 1089-1106. PMID 30776010 DOI: 10.3233/Jad-180923 |
0.797 |
|
| 2018 |
Ikezu T, Chen C, DeLeo AM, Zeldich E, Fallin MD, Kanaan NM, Lunetta KL, Abraham CR, Logue MW, Farrer LA. Tau Phosphorylation is Impacted by Rare AKAP9 Mutations Associated with Alzheimer Disease in African Americans. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 29516269 DOI: 10.1007/S11481-018-9781-X |
0.806 |
|
| 2018 |
Robinson AA, Abraham CR, Rosene DL. Candidate molecular pathways of white matter vulnerability in the brain of normal aging rhesus monkeys. Geroscience. PMID 29357021 DOI: 10.1007/s11357-018-0006-2 |
0.584 |
|
| 2018 |
Chen CD, Zeldich E, Li Y, Yuste A, Abraham CR. Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex. Journal of Molecular Neuroscience : Mn. PMID 29352444 DOI: 10.1007/S12031-017-1011-0 |
0.803 |
|
| 2017 |
Logue MW, Chen C, Zeldich E, Fallin MD, Abraham CR, Ikezu T, Farrer LA. Tau Phosphorylation Is Impacted By Rare Ad-Associated Akap9 Mutations Specific To African Americans Alzheimers & Dementia. 13: 969. DOI: 10.1016/J.Jalz.2017.06.1302 |
0.643 |
|
| 2016 |
Abraham CR, Mullen PC, Tucker-Zhou T, Chen CD, Zeldich E. Klotho Is a Neuroprotective and Cognition-Enhancing Protein. Vitamins and Hormones. 101: 215-38. PMID 27125744 DOI: 10.1016/Bs.Vh.2016.02.004 |
0.437 |
|
| 2015 |
Zeldich E, Chen CD, Avila R, Medicetty S, Abraham CR. The Anti-Aging Protein Klotho Enhances Remyelination Following Cuprizone-Induced Demyelination. Journal of Molecular Neuroscience : Mn. PMID 26067431 DOI: 10.1007/S12031-015-0598-2 |
0.792 |
|
| 2015 |
Dubal DB, Zhu L, Sanchez PE, Worden K, Broestl L, Johnson E, Ho K, Yu GQ, Kim D, Betourne A, Kuro-O M, Masliah E, Abraham CR, Mucke L. Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2358-71. PMID 25673831 DOI: 10.1523/Jneurosci.5791-12.2015 |
0.591 |
|
| 2015 |
Chen CD, Li H, Liang J, Hixson K, Zeldich E, Abraham CR. The anti-aging and tumor suppressor protein Klotho enhances differentiation of a human oligodendrocytic hybrid cell line. Journal of Molecular Neuroscience : Mn. 55: 76-90. PMID 24907942 DOI: 10.1007/S12031-014-0336-1 |
0.809 |
|
| 2014 |
Chen CD, Tung TY, Liang J, Zeldich E, Tucker Zhou TB, Turk BE, Abraham CR. Identification of cleavage sites leading to the shed form of the anti-aging protein klotho. Biochemistry. 53: 5579-87. PMID 25110992 DOI: 10.1021/Bi500409N |
0.79 |
|
| 2014 |
Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, ... ... Abraham CR, et al. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Annals of Neurology. 76: 379-92. PMID 25043464 DOI: 10.1002/Ana.24219 |
0.786 |
|
| 2014 |
Zeldich E, Chen CD, Colvin TA, Bove-Fenderson EA, Liang J, Tucker Zhou TB, Harris DA, Abraham CR. The neuroprotective effect of Klotho is mediated via regulation of members of the redox system. The Journal of Biological Chemistry. 289: 24700-15. PMID 25037225 DOI: 10.1074/Jbc.M114.567321 |
0.774 |
|
| 2014 |
Dubal DB, Yokoyama JS, Zhu L, Broestl L, Worden K, Wang D, Sturm VE, Kim D, Klein E, Yu GQ, Ho K, Eilertson KE, Yu L, Kuro-o M, De Jager PL, ... ... Abraham CR, et al. Life extension factor klotho enhances cognition. Cell Reports. 7: 1065-76. PMID 24813892 DOI: 10.1016/J.Celrep.2014.03.076 |
0.556 |
|
| 2014 |
Mehi SJ, Maltare A, Abraham CR, King GD. MicroRNA-339 and microRNA-556 regulate Klotho expression in vitro. Age (Dordrecht, Netherlands). 36: 141-9. PMID 23818104 DOI: 10.1007/S11357-013-9555-6 |
0.628 |
|
| 2013 |
Tucker Zhou TB, King GD, Chen C, Abraham CR. Biochemical and functional characterization of the klotho-VS polymorphism implicated in aging and disease risk. The Journal of Biological Chemistry. 288: 36302-11. PMID 24217253 DOI: 10.1074/Jbc.M113.490052 |
0.788 |
|
| 2013 |
So PP, Khodr CE, Chen CD, Abraham CR. Comparable dimerization found in wildtype and familial Alzheimer's disease amyloid precursor protein mutants. American Journal of Neurodegenerative Disease. 2: 15-28. PMID 23515184 |
0.808 |
|
| 2013 |
Chen CD, Sloane JA, Li H, Aytan N, Giannaris EL, Zeldich E, Hinman JD, Dedeoglu A, Rosene DL, Bansal R, Luebke JI, Kuro-o M, Abraham CR. The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1927-39. PMID 23365232 DOI: 10.1523/Jneurosci.2080-12.2013 |
0.795 |
|
| 2013 |
McKee AC, Stern RA, Nowinski CJ, Stein TD, Alvarez VE, Daneshvar DH, Lee HS, Wojtowicz SM, Hall G, Baugh CM, Riley DO, Kubilus CA, Cormier KA, Jacobs MA, Martin BR, ... Abraham CR, et al. The spectrum of disease in chronic traumatic encephalopathy. Brain : a Journal of Neurology. 136: 43-64. PMID 23208308 DOI: 10.1093/Brain/Aws307 |
0.726 |
|
| 2013 |
Zeldich E, Chen C, Abraham C. P3-068: Klotho gene protects primary hippocampal neurons from oxidative stress Alzheimer's & Dementia. 9: P575-P575. DOI: 10.1016/J.Jalz.2013.05.1138 |
0.673 |
|
| 2013 |
Jun G, Asai H, Drapeau E, Park J, Zeldich E, Chen C, Kim S, Foroud T, Lunetta K, Kim J, Buxbaum J, Abraham C, Ikezu T, Mayeux R, Farrer L. O4-06-02: Genetic variation in PLXNA4 associated with susceptibility of Alzheimer's disease through tau phosphorylation Alzheimer's & Dementia. 9: P692-P692. DOI: 10.1016/J.Jalz.2013.04.366 |
0.642 |
|
| 2013 |
Fisher A, Goldstein L, Tagge C, Velisek L, Wojnarowicz M, Moir R, Casey N, Moncaster J, Nowinski C, Blusztajn J, Wolozin B, Abraham C, Saman S, Upreti C, Ikezu T, et al. O1-07-02: Impact and blast neurotrauma mouse models of chronic traumatic encephalopathy validated by human neuropathology Alzheimer's & Dementia. 9: P141-P141. DOI: 10.1016/J.Jalz.2013.04.087 |
0.54 |
|
| 2012 |
Abraham CR, Chen C, Cuny GD, Glicksman MA, Zeldich E. Small-molecule Klotho enhancers as novel treatment of neurodegeneration. Future Medicinal Chemistry. 4: 1671-9. PMID 22924505 DOI: 10.4155/Fmc.12.134 |
0.815 |
|
| 2012 |
So PP, Zeldich E, Seyb KI, Huang MM, Concannon JB, King GD, Chen CD, Cuny GD, Glicksman MA, Abraham CR. Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization. American Journal of Neurodegenerative Disease. 1: 75-87. PMID 22822474 |
0.807 |
|
| 2012 |
King GD, Chen C, Huang MM, Zeldich E, Brazee PL, Schuman ER, Robin M, Cuny GD, Glicksman MA, Abraham CR. Identification of novel small molecules that elevate Klotho expression. The Biochemical Journal. 441: 453-61. PMID 21939436 DOI: 10.1042/Bj20101909 |
0.793 |
|
| 2012 |
King GD, Rosene DL, Abraham CR. Promoter methylation and age-related downregulation of Klotho in rhesus monkey. Age (Dordrecht, Netherlands). 34: 1405-19. PMID 21922250 DOI: 10.1007/S11357-011-9315-4 |
0.708 |
|
| 2012 |
Erlich PM, Lunetta KL, Cupples LA, Abraham CR, Green RC, Baldwin CT, Farrer LA. Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease. Neurobiology of Aging. 33: 1015.e7-23. PMID 20980077 DOI: 10.1016/J.Neurobiolaging.2010.08.003 |
0.475 |
|
| 2011 |
So PP, Chen CD, Abraham CR. Detection of amyloid-β protein precursor homo-interactions using beta-galactosidase enzyme fragment complementation. Journal of Alzheimer's Disease : Jad. 26: 647-55. PMID 21694460 DOI: 10.3233/Jad-2011-110323 |
0.809 |
|
| 2010 |
Oh SY, Chen CD, Abraham CR. Cell-type dependent modulation of Notch signaling by the amyloid precursor protein. Journal of Neurochemistry. 113: 262-74. PMID 20089128 DOI: 10.1111/J.1471-4159.2010.06603.X |
0.788 |
|
| 2010 |
Abraham CR, Chen C, King GD. P3-469: Development of Klotho enhancers as novel therapeutics for Alzheimer's disease Alzheimer's & Dementia. 6: S591-S591. DOI: 10.1016/J.Jalz.2010.05.2012 |
0.777 |
|
| 2010 |
Chen C, Abraham CR. P2-291: The functions of the anti-aging protein Klotho in the brain Alzheimer's & Dementia. 6: S399-S399. DOI: 10.1016/J.Jalz.2010.05.1341 |
0.73 |
|
| 2009 |
Yamin R, Zhao C, O'Connor PB, McKee AC, Abraham CR. Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide. Molecular Neurodegeneration. 4: 33. PMID 19627603 DOI: 10.1186/1750-1326-4-33 |
0.801 |
|
| 2008 |
Zerbinatti CV, Cordy JM, Chen CD, Guillily M, Suon S, Ray WJ, Seabrook GR, Abraham CR, Wolozin B. Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein. Molecular Neurodegeneration. 3: 5. PMID 18348724 DOI: 10.1186/1750-1326-3-5 |
0.745 |
|
| 2008 |
Hinman JD, Chen CD, Oh SY, Hollander W, Abraham CR. Age-dependent accumulation of ubiquitinated 2',3'-cyclic nucleotide 3'-phosphodiesterase in myelin lipid rafts. Glia. 56: 118-33. PMID 17963267 DOI: 10.1002/Glia.20595 |
0.8 |
|
| 2008 |
Duce JA, Podvin S, Hollander W, Kipling D, Rosene DL, Abraham CR. Gene profile analysis implicates Klotho as an important contributor to aging changes in brain white matter of the rhesus monkey. Glia. 56: 106-17. PMID 17963266 DOI: 10.1002/Glia.20593 |
0.799 |
|
| 2008 |
Abraham CR, Podvin S, King G, McKee A, Carreras I, Dedeoglu A, Chen C. O1-03-07: Klotho, aging and Alzheimer's Alzheimer's & Dementia. 4: T113-T114. DOI: 10.1016/J.Jalz.2008.05.235 |
0.782 |
|
| 2008 |
King GD, Chen C, Podvin S, Abraham CR. P4-186: Modulating Klotho expression to protect against age-induced neurodegeneration Alzheimer's & Dementia. 4: T725-T726. DOI: 10.1016/J.Jalz.2008.05.2253 |
0.783 |
|
| 2008 |
So P, Chen C, Abraham CR. P2-362: Detection of amyloid precursor protein dimerization in cells using enzyme fragment complementation and bimolecular fluorescent complementation Alzheimer's & Dementia. 4: T478-T479. DOI: 10.1016/J.Jalz.2008.05.1440 |
0.795 |
|
| 2007 |
Chen CD, Podvin S, Gillespie E, Leeman SE, Abraham CR. Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17. Proceedings of the National Academy of Sciences of the United States of America. 104: 19796-801. PMID 18056631 DOI: 10.1073/Pnas.0709805104 |
0.782 |
|
| 2007 |
Hinman JD, Abraham CR. What's behind the decline? The role of white matter in brain aging. Neurochemical Research. 32: 2023-31. PMID 17447140 DOI: 10.1007/S11064-007-9341-X |
0.774 |
|
| 2007 |
Yamin R, Bagchi S, Hildebrant R, Scaloni A, Widom RL, Abraham CR. Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-beta peptide. Journal of Neurochemistry. 100: 458-67. PMID 17241160 DOI: 10.1111/J.1471-4159.2006.04251.X |
0.807 |
|
| 2006 |
Chen CD, Oh SY, Hinman JD, Abraham CR. Visualization of APP dimerization and APP-Notch2 heterodimerization in living cells using bimolecular fluorescence complementation. Journal of Neurochemistry. 97: 30-43. PMID 16515557 DOI: 10.1111/J.1471-4159.2006.03705.X |
0.786 |
|
| 2006 |
Hinman JD, Peters A, Cabral H, Rosene DL, Hollander W, Rasband MN, Abraham CR. Age-related molecular reorganization at the node of Ranvier. The Journal of Comparative Neurology. 495: 351-62. PMID 16485288 DOI: 10.1002/Cne.20886 |
0.785 |
|
| 2006 |
Duce JA, Hollander W, Jaffe R, Abraham CR. Activation of early components of complement targets myelin and oligodendrocytes in the aged rhesus monkey brain. Neurobiology of Aging. 27: 633-44. PMID 15992964 DOI: 10.1016/J.Neurobiolaging.2005.03.027 |
0.676 |
|
| 2006 |
ABRAHAM CR, McGRAW WT, SLOT F, YAMIN R. α1-Antichymotrypsin Inhibits Aβ Degradation in Vitro and in Vivo Annals of the New York Academy of Sciences. 920: 245-248. DOI: 10.1111/J.1749-6632.2000.Tb06930.X |
0.8 |
|
| 2006 |
Cordy JM, Zerbinatti CV, Chen C, Guillily M, Ray WJ, Seabrook GR, Abraham CR, Wolozin B. P4-077: Modulation of amyloid precursor protein-processing by oxysterol-binding protein Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1815 |
0.725 |
|
| 2006 |
Chen C, Oh S, Abraham CR. P4-002: Bimolecular fluorescence complementation studies of APP homodimerization and heterodimerization Alzheimer's & Dementia. 2: S514-S514. DOI: 10.1016/J.Jalz.2006.05.1740 |
0.723 |
|
| 2005 |
Oh SY, Ellenstein A, Chen CD, Hinman JD, Berg EA, Costello CE, Yamin R, Neve RL, Abraham CR. Amyloid precursor protein interacts with notch receptors. Journal of Neuroscience Research. 82: 32-42. PMID 16118793 DOI: 10.1002/Jnr.20625 |
0.796 |
|
| 2004 |
Hinman JD, Duce JA, Siman RA, Hollander W, Abraham CR. Activation of calpain-1 in myelin and microglia in the white matter of the aged rhesus monkey. Journal of Neurochemistry. 89: 430-41. PMID 15056286 DOI: 10.1046/J.1471-4159.2004.02348.X |
0.803 |
|
| 2004 |
Abraham CR, Oh S, Ellenstein A, Berg E, O'Connor P, Costello C, Van Nostrand WE, Neve R. P1-201 In search for APP-binding proteins Neurobiology of Aging. 25: S153. DOI: 10.1016/S0197-4580(04)80514-1 |
0.782 |
|
| 2003 |
Sloane JA, Hinman JD, Lubonia M, Hollander W, Abraham CR. Age-dependent myelin degeneration and proteolysis of oligodendrocyte proteins is associated with the activation of calpain-1 in the rhesus monkey. Journal of Neurochemistry. 84: 157-68. PMID 12485412 DOI: 10.1046/J.1471-4159.2003.01541.X |
0.799 |
|
| 2001 |
Abraham CR. Reactive astrocytes and alpha1-antichymotrypsin in Alzheimer's disease. Neurobiology of Aging. 22: 931-6. PMID 11755001 DOI: 10.1016/S0197-4580(01)00302-5 |
0.433 |
|
| 2000 |
Abraham CR, McGraw WT, Slot F, Yamin R. Alpha 1-antichymotrypsin inhibits A beta degradation in vitro and in vivo. Annals of the New York Academy of Sciences. 920: 245-8. PMID 11193158 |
0.807 |
|
| 2000 |
Mucke L, Yu GQ, McConlogue L, Rockenstein EM, Abraham CR, Masliah E. Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice. The American Journal of Pathology. 157: 2003-10. PMID 11106573 DOI: 10.1016/S0002-9440(10)64839-0 |
0.622 |
|
| 2000 |
Abraham CR. Amyloid beta peptide: a century of discoveries. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 7: 7-9. PMID 10842695 DOI: 10.3109/13506120009146814 |
0.312 |
|
| 2000 |
Sloane JA, Hollander W, Rosene DL, Moss MB, Kemper T, Abraham CR. Astrocytic hypertrophy and altered GFAP degradation with age in subcortical white matter of the rhesus monkey. Brain Research. 862: 1-10. PMID 10799662 DOI: 10.1016/S0006-8993(00)02059-X |
0.764 |
|
| 2000 |
Slot F, Abraham CR. Specific cleavage and nuclear localization of metalloendopeptidase EC3.4.24.15 Neurobiology of Aging. 21: 260. DOI: 10.1016/S0197-4580(00)83125-5 |
0.761 |
|
| 2000 |
Abraham CR, Yamin R, Berg EA, Gartner M, Fine RE, McGraw WT. Bleomycin hydrolase alters amyloid precursor protein trafficking, aβsecretion and the Aβ42/Aβ40 ratio in a dose dependent manner Neurobiology of Aging. 21: 260. DOI: 10.1016/S0197-4580(00)83124-3 |
0.793 |
|
| 2000 |
Yamin R, Masliah E, Macke L, Abraham CR. Amyloidogenic effects of α1-antichymotrypsin in vitro and in vivo Neurobiology of Aging. 21: 260. DOI: 10.1016/S0197-4580(00)83123-1 |
0.743 |
|
| 2000 |
Ellenstein A, Abraham CR. Amyloid precursor protein binding partners in human embryonic kidney 293 cells Neurobiology of Aging. 21: 260. DOI: 10.1016/S0197-4580(00)83121-8 |
0.8 |
|
| 1999 |
Sloane JA, Hollander W, Moss MB, Rosene DL, Abraham CR. Increased microglial activation and protein nitration in white matter of the aging monkey. Neurobiology of Aging. 20: 395-405. PMID 10604432 DOI: 10.1016/S0197-4580(99)00066-4 |
0.759 |
|
| 1999 |
Yamin R, Malgeri EG, Sloane JA, McGraw WT, Abraham CR. Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation. The Journal of Biological Chemistry. 274: 18777-84. PMID 10373494 DOI: 10.1074/Jbc.274.26.18777 |
0.808 |
|
| 1999 |
Abraham CR, Marshall DC, Tibbles HE, Otto K, Long HJ, Billingslea AM, Hastey R, Johnson R, Fine RE, Smith SJ, Simons ER, Davies TA. Platelets and DAMI megakaryocytes possess beta-secretase-like activity. The Journal of Laboratory and Clinical Medicine. 133: 507-15. PMID 10235134 DOI: 10.1016/S0022-2143(99)90028-8 |
0.353 |
|
| 1998 |
Farrer LA, Abraham CR, Haines JL, Rogaeva EA, Song Y, McGraw WT, Brindle N, Premkumar S, Scott WK, Yamaoka LH, Saunders AM, Roses AD, Auerbach SA, Sorbi S, Duara R, et al. Association between bleomycin hydrolase and Alzheimer's disease in caucasians. Annals of Neurology. 44: 808-11. PMID 9818937 DOI: 10.1002/Ana.410440515 |
0.495 |
|
| 1998 |
Simons ER, Marshall DC, Long HJ, Otto K, Billingslea A, Tibbles H, Wells J, Eisenhauer P, Fine RE, Cribbs DH, Davies TA, Abraham CR. Blood brain barrier endothelial cells express candidate amyloid precursor protein-cleaving secretases. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 5: 153-62. PMID 9818052 DOI: 10.3109/13506129809003841 |
0.377 |
|
| 1998 |
Meckelein B, Marshall DC, Conn KJ, Pietropaolo M, Van Nostrand W, Abraham CR. Identification of a novel serine protease-like molecule in human brain. Brain Research. Molecular Brain Research. 55: 181-97. PMID 9582421 DOI: 10.1016/S0169-328X(97)00366-5 |
0.431 |
|
| 1998 |
Slot F, Olsen AS, Nagesh Rao P, Abraham CR. Localization of human endopeptidase EC 3.4.24.15 (THOP1) to chromosome 19p13.3 Alzheimer's Reports. 1: 327-331. |
0.758 |
|
| 1997 |
Sloane JA, Pietropaolo MF, Rosene DL, Moss MB, Peters A, Kemper T, Abraham CR. Lack of correlation between plaque burden and cognition in the aged monkey. Acta Neuropathologica. 94: 471-8. PMID 9386780 DOI: 10.1007/S004010050735 |
0.77 |
|
| 1997 |
Aleshkov S, Abraham CR, Zannis VI. Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease. Biochemistry. 36: 10571-80. PMID 9265639 DOI: 10.1021/Bi9626362 |
0.437 |
|
| 1997 |
Liang JS, Sloane JA, Wells JM, Abraham CR, Fine RE, Sipe JD. Evidence for local production of acute phase response apolipoprotein serum amyloid A in Alzheimer's disease brain. Neuroscience Letters. 225: 73-6. PMID 9147377 DOI: 10.1016/S0304-3940(97)00196-1 |
0.709 |
|
| 1997 |
Masliah E, Westland CE, Rockenstein EM, Abraham CR, Mallory M, Veinberg I, Sheldon E, Mucke L. Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo. Neuroscience. 78: 135-46. PMID 9135095 DOI: 10.1016/S0306-4522(96)00553-2 |
0.598 |
|
| 1997 |
Fine RE, Abraham CR. Hypothesis: β amyloid precursor protein is a key sorting and targeting receptor for neuropeptidases Amyloid. 4: 233-239. DOI: 10.3109/13506129709003834 |
0.379 |
|
| 1996 |
Kanemaru K, Meckelein B, Marshall DC, Sipe JD, Abraham CR. Synthesis and secretion of active alpha 1-antichymotrypsin by murine primary astrocytes. Neurobiology of Aging. 17: 767-71. PMID 8892350 DOI: 10.1016/0197-4580(96)00111-X |
0.683 |
|
| 1996 |
Conn KJ, Pietropaolo M, Ju ST, Abraham CR. Monoclonal antibodies against the human metalloprotease EC 3.4.24.15 label neurofibrillary tangles in Alzheimer's disease brain. Journal of Neurochemistry. 66: 2011-8. PMID 8780030 DOI: 10.1046/J.1471-4159.1996.66052011.X |
0.442 |
|
| 1996 |
Peters A, Rosene DL, Moss MB, Kemper TL, Abraham CR, Tigges J, Albert MS. Neurobiological bases of age-related cognitive decline in the rhesus monkey. Journal of Neuropathology and Experimental Neurology. 55: 861-74. PMID 8759775 DOI: 10.1097/00005072-199608000-00001 |
0.583 |
|
| 1996 |
Mucke L, Abraham CR, Masliah E. Neurotrophic and neuroprotective effects of hAPP in transgenic mice. Annals of the New York Academy of Sciences. 777: 82-8. PMID 8624131 DOI: 10.1111/J.1749-6632.1996.Tb34405.X |
0.595 |
|
| 1996 |
Chang T, Abraham CR. A novel brain cysteine protease forms an SDS stable complex with the beta-amyloid precursor protein. Annals of the New York Academy of Sciences. 777: 183-8. PMID 8624082 DOI: 10.1111/J.1749-6632.1996.Tb34417.X |
0.408 |
|
| 1996 |
Sloane J, Pietropaolo M, Rosene D, Moss M, Peters A, Kemper T, Abraham C. 269 Lack of correlation between plaque burden and cognition in the aging monkey Neurobiology of Aging. 17: S67-S68. DOI: 10.1016/S0197-4580(96)80271-5 |
0.737 |
|
| 1995 |
Mucke L, Abraham CR, Ruppe MD, Rockenstein EM, Toggas SM, Mallory M, Alford M, Masliah E. Protection against HIV-1 gp120-induced brain damage by neuronal expression of human amyloid precursor protein. The Journal of Experimental Medicine. 181: 1551-6. PMID 7699335 DOI: 10.1084/Jem.181.4.1551 |
0.586 |
|
| 1995 |
Farrer LA, Abraham CR, Volicer L, Foley EJ, Kowall NW, McKee AC, Wells JM. Allele epsilon 4 of apolipoprotein E shows a dose effect on age at onset of Pick disease. Experimental Neurology. 136: 162-70. PMID 7498406 DOI: 10.1006/Exnr.1995.1093 |
0.529 |
|
| 1995 |
Wells JM, Amaratunga A, Mckenna DC, Abraham CR, Fine RE. Amyloid βprotein precursor and apolipoprotein e production in cultured cerebral endothelial cells isolated from brains of patients with neurodegenerative disorders at autopsy Amyloid. 2: 229-233. DOI: 10.3109/13506129508999004 |
0.329 |
|
| 1995 |
Chang T, Abraham CR. A NOVEL BRAIN CYSTEINE PROTEASE IS CAPABLE OF PROCESSING THE B AMYLOID PRECURSOR PROTEIN Journal of Neuropathology and Experimental Neurology. 54: 412. DOI: 10.1097/00005072-199505000-00023 |
0.383 |
|
| 1994 |
Papastoitsis G, Siman R, Scott R, Abraham CR. Identification of a metalloprotease from Alzheimer's disease brain able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments. Biochemistry. 33: 192-9. PMID 8286339 DOI: 10.1021/Bi00167A025 |
0.804 |
|
| 1994 |
Toggas SM, Masliah E, Rockenstein EM, Rall GF, Abraham CR, Mucke L. Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice. Nature. 367: 188-93. PMID 8114918 DOI: 10.1038/367188a0 |
0.493 |
|
| 1994 |
Mucke L, Masliah E, Johnson WB, Ruppe MD, Alford M, Rockenstein EM, Forss-Petter S, Pietropaolo M, Mallory M, Abraham CR. Synaptotrophic effects of human amyloid beta protein precursors in the cortex of transgenic mice. Brain Research. 666: 151-67. PMID 7882025 DOI: 10.1016/0006-8993(94)90767-6 |
0.645 |
|
| 1994 |
Conn KJ, Papastoitsis G, Meckelein B, Abraham CR. Identification of full length βamyloid precursor protein in human neuronal and non-neuronal cell culture supernatant: A possible extracellular source for the generation of aβ Amyloid. 1: 232-239. DOI: 10.3109/13506129409146114 |
0.827 |
|
| 1994 |
Papastoitsis G, Siman R, Scott R, Abraham CR. Identification of a metalloprotease from Alzheimer's disease brain able to degrade the β-amyloid precursor protein and generate amyloidogenic fragments Biochemistry. 33: 192-199. |
0.305 |
|
| 1993 |
Fraser PE, Nguyen JT, McLachlan DR, Abraham CR, Kirschner DA. Alpha 1-antichymotrypsin binding to Alzheimer A beta peptides is sequence specific and induces fibril disaggregation in vitro. Journal of Neurochemistry. 61: 298-305. PMID 8515277 DOI: 10.1111/J.1471-4159.1993.Tb03568.X |
0.381 |
|
| 1993 |
Razzaboni BL, Meckelein B, Abraham CR. Purification and cloning of monkey proteases involved in the processing of the beta-amyloid precursor protein. Neurobiology of Aging. 14: 677-9. PMID 8295685 DOI: 10.1016/0197-4580(93)90069-N |
0.376 |
|
| 1993 |
Stone PJ, Campistol JM, Abraham CR, Rodgers O, Shirahama T, Skinner M. Neutrophil proteases associated with amyloid fibrils. Biochemical and Biophysical Research Communications. 197: 130-6. PMID 8250917 DOI: 10.1006/Bbrc.1993.2451 |
0.366 |
|
| 1993 |
Abraham CR, Kanemaru K, Mucke L. Expression of cathepsin G-like and alpha 1-antichymotrypsin-like proteins in reactive astrocytes. Brain Research. 621: 222-32. PMID 8242336 DOI: 10.1016/0006-8993(93)90110-9 |
0.718 |
|
| 1993 |
Campbell IL, Abraham CR, Masliah E, Kemper P, Inglis JD, Oldstone MB, Mucke L. Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6. Proceedings of the National Academy of Sciences of the United States of America. 90: 10061-5. PMID 7694279 DOI: 10.1073/Pnas.90.21.10061 |
0.551 |
|
| 1992 |
Razzaboni BL, Papastoitsis G, Koo EH, Abraham CR. A calcium-stimulated serine protease from monkey brain degrades the beta-amyloid precursor protein. Brain Research. 589: 207-16. PMID 1393590 DOI: 10.1016/0006-8993(92)91279-N |
0.826 |
|
| 1992 |
Abraham CR, Razzaboni BL, Papastoitsis G, Picard E, Kanemaru K, Meckelein B, Mucke L. Purification and cloning of brain proteases capable of degrading the beta-amyloid precursor protein. Annals of the New York Academy of Sciences. 674: 174-9. PMID 1288362 DOI: 10.1111/J.1749-6632.1992.Tb27486.X |
0.806 |
|
| 1992 |
Campistol JM, Shirahama T, Abraham CR, Rodgers OG, Solé M, Cohen AS, Skinner M. Demonstration of plasma proteinase inhibitors in beta 2-microglobulin amyloid deposits. Kidney International. 42: 915-23. PMID 1280700 DOI: 10.1038/Ki.1992.368 |
0.337 |
|
| 1991 |
Abraham CR, Driscoll J, Potter H, Van Nostrand WE, Tempst P. A calcium-activated protease from Alzheimer's disease brain cleaves at the N-terminus of the amyloid beta-protein. Biochemical and Biophysical Research Communications. 174: 790-6. PMID 1993072 DOI: 10.1016/0006-291X(91)91487-W |
0.583 |
|
| 1991 |
Koo EH, Abraham CR, Potter H, Cork LC, Price DL. Developmental expression of alpha 1-antichymotrypsin in brain may be related to astrogliosis. Neurobiology of Aging. 12: 495-501. PMID 1837594 DOI: 10.1016/0197-4580(91)90079-Y |
0.685 |
|
| 1991 |
Abraham CR, Razzaboni BL, Sisodia SS, Koo EH, Price DL, Van Nostrand WE, Papastoitsis G. Studies on the proteolytic degradation of the beta-protein precursor by proteases purified from Alzheimer's disease brain. Annals of the New York Academy of Sciences. 640: 161-5. PMID 1776735 DOI: 10.1111/J.1749-6632.1991.Tb00209.X |
0.808 |
|
| 1991 |
Richards SJ, Waters JJ, Beyreuther K, Masters CL, Wischik CM, Sparkman DR, White CL, Abraham CR, Dunnett SB. Transplants of mouse trisomy 16 hippocampus provide a model of Alzheimer's disease neuropathology. The Embo Journal. 10: 297-303. DOI: 10.1002/J.1460-2075.1991.Tb07950.X |
0.359 |
|
| 1990 |
Abraham CR, Shirahama T, Potter H. Alpha 1-antichymotrypsin is associated solely with amyloid deposits containing the beta-protein. Amyloid and cell localization of alpha 1-antichymotrypsin. Neurobiology of Aging. 11: 123-9. PMID 2190106 DOI: 10.1016/0197-4580(90)90045-2 |
0.607 |
|
| 1990 |
Abraham CR, Nostrand WV, Driscoll J. A NOVEL CALCIUM-DEPENDENT SERINE PROTEASE FROM BRAIN CLEAVES β-PROTEIN-RELATED SYNTHETIC PEPTIDES AND IS INHIBITED BY α-ANTICHYMOTRYPSIN AND PROTEASE NEXIN 2 Journal of Neuropathology and Experimental Neurology. 49: 333. DOI: 10.1097/00005072-199005000-00222 |
0.312 |
|
| 1989 |
Abraham CR, Selkoe DJ, Potter H, Price DL, Cork LC. Alpha 1-antichymotrypsin is present together with the beta-protein in monkey brain amyloid deposits. Neuroscience. 32: 715-20. PMID 2689908 DOI: 10.1016/0306-4522(89)90292-3 |
0.724 |
|
| 1989 |
Abraham CR. Potential roles of protease inhibitors in Alzheimer's disease. Neurobiology of Aging. 10: 463-5; discussion 47. PMID 2682323 DOI: 10.1016/0197-4580(89)90097-3 |
0.38 |
|
| 1989 |
Abraham CR, Potter H. The protease inhibitor, alpha 1-antichymotrypsin, is a component of the brain amyloid deposits in normal aging and Alzheimer's disease. Annals of Medicine. 21: 77-81. PMID 2669847 DOI: 10.3109/07853898909149188 |
0.591 |
|
| 1989 |
Abraham CR, Potter H. Alpha 1-antichymotrypsin in brain aging and disease. Progress in Clinical and Biological Research. 317: 1037-48. PMID 2513582 |
0.516 |
|
| 1989 |
Pasternack J, Abraham C, Dyke BV, Potter H, Younkln S. ASTROCYTES IN ALZHEIMERʼS DISEASE GRAY MATTER EXPRESS α1 ANTICHYMOTRYPSIN mRNA Journal of Neuropathology and Experimental Neurology. 48: 328. DOI: 10.1097/00005072-198905000-00087 |
0.473 |
|
| 1989 |
Abraham CR, Potter H. Alzheimer's disease: Recent advances in understanding the brain amyloid deposits Bio/Technology. 7: 147-153. DOI: 10.1038/Nbt0289-147 |
0.536 |
|
| 1988 |
Abraham CR, Selkoe DJ, Potter H. Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell. 52: 487-501. PMID 3257719 DOI: 10.1016/0092-8674(88)90462-X |
0.687 |
|
| 1988 |
ABRAHAM CR, SELKOE DJ, POTTER H. ??1-ANTICHYMOTRYPSIN IN BRAIN AGING AND DISEASE Alzheimer Disease & Associated Disorders. 2: 259. DOI: 10.1097/00002093-198802030-00108 |
0.681 |
|
| 1987 |
Duffy LK, Abraham CR, Berman‐Podlisny M, Walsh RL, Selkoe DJ. HPLC Analysis of Proteins from Alzheimer Paired Helical Filaments Annals of the New York Academy of Sciences. 494: 369-372. DOI: 10.1111/J.1749-6632.1987.Tb29575.X |
0.617 |
|
| 1987 |
Rasool C, Abraham C, Anderton B, Haugh M, Kahn J, Selkoe D. Alzheimerʼs disease: immunoreactivity of neurofibrillary tangles with anti-neurofilament and anti-paired helical filament antibodies Alzheimer Disease & Associated Disorders. 1: 267. DOI: 10.1097/00002093-198701040-00020 |
0.502 |
|
| 1987 |
Kosik K, Duffy L, Dowling M, Abraham C, McCluskey A, Selkoe D. Microtubule-associated protein 2: monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles Alzheimer Disease & Associated Disorders. 1: 266. DOI: 10.1097/00002093-198701040-00018 |
0.475 |
|
| 1986 |
Selkoe DJ, Abraham CR. Isolation of paired helical filaments and amyloid fibers from human brain. Methods in Enzymology. 134: 388-404. PMID 3821571 DOI: 10.1016/0076-6879(86)34105-3 |
0.583 |
|
| 1986 |
Selkoe DJ, Abraham CR, Podlisny MB, Duffy LK. Isolation of low-molecular-weight proteins from amyloid plaque fibers in Alzheimer's disease. Journal of Neurochemistry. 46: 1820-34. PMID 3517233 DOI: 10.1111/J.1471-4159.1986.Tb08501.X |
0.652 |
|
| 1986 |
Kirschner DA, Abraham C, Selkoe DJ. X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation. Proceedings of the National Academy of Sciences of the United States of America. 83: 503-7. PMID 3455785 DOI: 10.1073/Pnas.83.2.503 |
0.587 |
|
| 1986 |
Selkoe D, Podlisny M, Galibert L, Abraham C, Duffy L. PRODUCTION OF AMYLOID-SPECIFIC ANTIBODIES TO LOW MOLECULAR WEIGHT PROTEINS ISOLATED FROM ALZHEIMERʼS DISEASE (AD) BRAIN Journal of Neuropathology and Experimental Neurology. 45: 360. DOI: 10.1097/00005072-198605000-00139 |
0.628 |
|
| 1985 |
Selkoe DJ, Abraham C, Rasool CG, McCluskey A, Kosik KS, Duffy LK. Paired helical filaments in human neurons: relationship to neurofilaments Annals of the New York Academy of Sciences. 455: 583-596. PMID 3936387 DOI: 10.1111/J.1749-6632.1985.Tb50438.X |
0.64 |
|
| 1985 |
SELKOE DJ, ABRAHAM C, RASOOL CG, McCLUSKEY A, DUFFY LK. Production and Characterization of Monoclonal Antibodies to Alzheimer Paired Helical Filaments Annals of the New York Academy of Sciences. 455: 774-778. DOI: 10.1111/J.1749-6632.1985.Tb50472.X |
0.563 |
|
| 1984 |
Rasool CG, Abraham C, Anderton BH, Haugh M, Kahn J, Selkoe DJ. Alzheimer's disease: immunoreactivity of neurofibrillary tangles with anti-neurofilament and anti-paired helical filament antibodies. Brain Research. 310: 249-60. PMID 6207891 DOI: 10.1016/0006-8993(84)90148-3 |
0.606 |
|
| 1984 |
Kosik KS, Duffy LK, Dowling MM, Abraham C, McCluskey A, Selkoe DJ. Microtubule-associated protein 2: Monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles Proceedings of the National Academy of Sciences of the United States of America. 81: 7941-7945. PMID 6083566 DOI: 10.1073/Pnas.81.24.7941 |
0.685 |
|
| 1984 |
Selkoe DJ, Abraham C, Rasool CG, McCluskey A, Duffy LK. 161 MONOCLONAL ANTIBODIES TO ALZHEIMER PAIRED HELICAL FILAMENTS PRODUCED BY RAT-MOUSE HYBRIDOMAS Journal of Neuropathology and Experimental Neurology. 43: 346. DOI: 10.1097/00005072-198405000-00167 |
0.563 |
|
| 1983 |
Ihara Y, Abraham C, Selkoe DJ. Antibodies to paired helical filaments in Alzheimer's disease do not recognize normal brain proteins. Nature. 304: 727-30. PMID 6350889 DOI: 10.1038/304727A0 |
0.657 |
|
| 1983 |
Selkoe D, Abraham C, Ihara Y, Pope A. 105 ANTIBODIES TO THE FAIL TO REACT WITH NEUROFILAMENTS AND OTHER NORMAL PROTEINS Journal of Neuropathology and Experimental Neurology. 42: 340. DOI: 10.1097/00005072-198305000-00112 |
0.571 |
|
| 1982 |
Selkoe DJ, Salazar FJ, Abraham C, Kosik KS. Huntington's disease: changes in striatal proteins reflect astrocytic gliosis. Brain Research. 245: 117-25. PMID 6214299 DOI: 10.1016/0006-8993(82)90344-4 |
0.684 |
|
| 1982 |
Selkoe DJ, Abraham C, Ihara Y. Brain transglutaminase: in vitro crosslinking of human neurofilament proteins into insoluble polymers. Proceedings of the National Academy of Sciences of the United States of America. 79: 6070-4. PMID 6136967 DOI: 10.1073/Pnas.79.19.6070 |
0.632 |
|
| 1982 |
Selkoe DJ, Abraham C, Ihara Y. CROSSLINKING OF ALZHEIMER PAIRED HELICAL FILAMENTS Journal of Neuropathology and Experimental Neurology. 41: 354. DOI: 10.1097/00005072-198205000-00048 |
0.582 |
|
| Show low-probability matches. |
