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Frederic H. Vaillancourt, Ph.D. - Publications

Affiliations: 
2002 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Biochemistry, Environmental Engineering
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yao S, Nguyen TV, Rolfe A, Agrawal AA, Ke J, Peng S, Colombo F, Yu S, Bouchard P, Wu J, Huang KC, Bao X, Omoto K, Selvaraj A, Yu L, ... ... Vaillancourt FH, et al. Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. Cell Chemical Biology. PMID 32017919 DOI: 10.1016/J.Chembiol.2020.01.009  0.316
2009 Matthews ML, Krest CM, Barr EW, Vaillancourt FH, Walsh CT, Green MT, Krebs C, Bollinger JM. Substrate-triggered formation and remarkable stability of the C-H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2. Biochemistry. 48: 4331-43. PMID 19245217 DOI: 10.1021/Bi900109Z  0.412
2007 Singh GM, Vaillancourt FH, Yin J, Walsh CT. Characterization of SyrC, an aminoacyltransferase shuttling threonyl and chlorothreonyl residues in the syringomycin biosynthetic assembly line. Chemistry & Biology. 14: 31-40. PMID 17254950 DOI: 10.1016/J.Chembiol.2006.11.005  0.366
2006 Ueki M, Galoni? DP, Vaillancourt FH, Garneau-Tsodikova S, Yeh E, Vosburg DA, Schroeder FC, Osada H, Walsh CT. Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete. Chemistry & Biology. 13: 1183-91. PMID 17114000 DOI: 10.1016/J.Chembiol.2006.09.012  0.354
2006 Vaillancourt FH, Bolin JT, Eltis LD. The ins and outs of ring-cleaving dioxygenases. Critical Reviews in Biochemistry and Molecular Biology. 41: 241-67. PMID 16849108 DOI: 10.1080/10409230600817422  0.629
2006 Galonić DP, Vaillancourt FH, Walsh CT. Halogenation of unactivated carbon centers in natural product biosynthesis: trichlorination of leucine during barbamide biosynthesis. Journal of the American Chemical Society. 128: 3900-1. PMID 16551084 DOI: 10.1021/Ja060151N  0.403
2006 Blasiak LC, Vaillancourt FH, Walsh CT, Drennan CL. Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis. Nature. 440: 368-71. PMID 16541079 DOI: 10.1038/Nature04544  0.389
2005 Horsman GP, Jirasek A, Vaillancourt FH, Barbosa CJ, Jarzecki AA, Xu C, Mekmouche Y, Spiro TG, Lipscomb JD, Blades MW, Turner RF, Eltis LD. Spectroscopic studies of the anaerobic enzyme-substrate complex of catechol 1,2-dioxygenase. Journal of the American Chemical Society. 127: 16882-91. PMID 16316234 DOI: 10.1021/Ja053800O  0.694
2005 Vaillancourt FH, Fortin PD, Labbé G, Drouin NM, Karim Z, Agar NY, Eltis LD. Molecular basis for the substrate selectivity of bicyclic and monocyclic extradiol dioxygenases. Biochemical and Biophysical Research Communications. 338: 215-22. PMID 16165093 DOI: 10.1016/J.Bbrc.2005.08.219  0.625
2005 Vaillancourt FH, Yeh E, Vosburg DA, O'Connor SE, Walsh CT. Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis. Nature. 436: 1191-4. PMID 16121186 DOI: 10.1038/Nature03797  0.418
2005 Vaillancourt FH, Yin J, Walsh CT. SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase. Proceedings of the National Academy of Sciences of the United States of America. 102: 10111-6. PMID 16002467 DOI: 10.1073/Pnas.0504412102  0.396
2005 Veldhuizen EJ, Vaillancourt FH, Whiting CJ, Hsiao MM, Gingras G, Xiao Y, Tanguay RM, Boukouvalas J, Eltis LD. Steady-state kinetics and inhibition of anaerobically purified human homogentisate 1,2-dioxygenase. The Biochemical Journal. 386: 305-14. PMID 15479158 DOI: 10.1042/Bj20041370  0.627
2004 Tseng CC, Vaillancourt FH, Bruner SD, Walsh CT. DpgC is a metal- and cofactor-free 3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase in the vancomycin biosynthetic pathway. Chemistry & Biology. 11: 1195-203. PMID 15380180 DOI: 10.1016/J.Chembiol.2004.06.012  0.421
2004 Jirasek A, Horsman GP, Vaillancourt FH, Barbosa CJ, Eltis LD, Blades MW, Turner RFB. Probing enzyme-substrate interactions using fiber-optic ultraviolet resonance Raman spectroscopy American Pharmaceutical Review. 7: 49-53.  0.527
2003 Davis MI, Wasinger EC, Decker A, Pau MY, Vaillancourt FH, Bolin JT, Eltis LD, Hedman B, Hodgson KO, Solomon EI. Spectroscopic and electronic structure studies of 2,3-dihydroxybiphenyl 1,2-dioxygenase: O2 reactivity of the non-heme ferrous site in extradiol dioxygenases. Journal of the American Chemical Society. 125: 11214-27. PMID 16220940 DOI: 10.1021/Ja029746I  0.619
2003 Vaillancourt FH, Haro MA, Drouin NM, Karim Z, Maaroufi H, Eltis LD. Characterization of extradiol dioxygenases from a polychlorinated biphenyl-degrading strain that possess higher specificities for chlorinated metabolites. Journal of Bacteriology. 185: 1253-60. PMID 12562795 DOI: 10.1128/Jb.185.4.1253-1260.2003  0.605
2002 Dai S, Vaillancourt FH, Maaroufi H, Drouin NM, Neau DB, Snieckus V, Bolin JT, Eltis LD. Identification and analysis of a bottleneck in PCB biodegradation. Nature Structural Biology. 9: 934-9. PMID 12415290 DOI: 10.1038/Nsb866  0.57
2002 Ge Y, Vaillancourt FH, Agar NY, Eltis LD. Reactivity of toluate dioxygenase with substituted benzoates and dioxygen. Journal of Bacteriology. 184: 4096-103. PMID 12107126 DOI: 10.1128/Jb.184.15.4096-4103.2002  0.644
2002 Vaillancourt FH, Barbosa CJ, Spiro TG, Bolin JT, Blades MW, Turner RFB, Eltis LD. Definitive evidence for monoanionic binding of 2,3-dihydroxybiphenyl to 2,3-dihydroxybiphenyl 1,2-dioxygenase from UV resonance Raman spectroscopy, UV/Vis absorption spectroscopy, and crystallography Journal of the American Chemical Society. 124: 2485-2496. PMID 11890797 DOI: 10.1021/Ja0174682  0.597
2002 Vaillancourt FH, Labbe G, Drouin NM, Fortin PD, Eltis LD. The mechanism-based inactivation of 2,3-dihydroxybiphenyl 1,2-dioxygenase by catecholic substrates. The Journal of Biological Chemistry. 277: 2019-27. PMID 11707443 DOI: 10.1074/Jbc.M106890200  0.656
2002 Barbosa CJ, Vaillancourt FH, Eltis LD, Blades MW, Turner RFB. The power distribution advantage of fiber-optic coupled ultraviolet resonance Raman spectroscopy for bioanalytical and biomedical applications Journal of Raman Spectroscopy. 33: 503-510. DOI: 10.1002/Jrs.878  0.499
1998 Vaillancourt FH, Han S, Fortin PD, Bolin JT, Eltis LD. Molecular basis for the stabilization and inhibition of 2, 3-dihydroxybiphenyl 1,2-dioxygenase by t-butanol. The Journal of Biological Chemistry. 273: 34887-95. PMID 9857017 DOI: 10.1074/Jbc.273.52.34887  0.62
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