Jyothi Rengarajan, Ph.D. - Publications

Affiliations: 
2001 Harvard University, Cambridge, MA, United States 
Area:
Molecular Biology, Cell Biology

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Esmael A, Mihret A, Abebe T, Mussa D, Neway S, Ernst J, Rengarajan J, Wassie L, Howe R. Persistent expression of activation markers on Mycobacterium tuberculosis-specific CD4 T cells in smear negative TB patients. Plos One. 17: e0271234. PMID 36040958 DOI: 10.1371/journal.pone.0271234  0.386
2022 Enriquez AB, Sia JK, Dkhar HK, Goh SL, Quezada M, Stallings KL, Rengarajan J. impedes CD40-dependent notch signaling to restrict Th polarization during infection. Iscience. 25: 104305. PMID 35586066 DOI: 10.1016/j.isci.2022.104305  0.309
2022 Esmael A, Abebe T, Mihret A, Mussa D, Neway S, Ernst J, Rengarajan J, Wassie L, Howe R. Mycobacterium tuberculosis antigen-specific T cell responses in smear- negative pulmonary tuberculosis patients. Clinical and Experimental Immunology. PMID 35552657 DOI: 10.1093/cei/uxac049  0.388
2021 Sharan R, Ganatra SR, Bucsan AN, Cole J, Singh DK, Alvarez X, Gough M, Alvarez C, Blakley A, Ferdin J, Thippeshappa R, Singh B, Escobedo R, Shivanna V, Dick EJ, ... ... Rengarajan J, et al. Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a tuberculosis/simian immunodeficiency virus coinfection model. The Journal of Clinical Investigation. PMID 34855621 DOI: 10.1172/JCI153090  0.396
2021 Sharan R, Singh DK, Rengarajan J, Kaushal D. Characterizing Early T Cell Responses in Nonhuman Primate Model of Tuberculosis. Frontiers in Immunology. 12: 706723. PMID 34484203 DOI: 10.3389/fimmu.2021.706723  0.412
2020 Shanmugasundaram U, Bucsan AN, Ganatra SR, Ibegbu C, Quezada M, Blair RV, Alvarez X, Velu V, Kaushal D, Rengarajan J. Pulmonary Mycobacterium tuberculosis control associates with CXCR3- and CCR6-expressing antigen-specific Th1 and Th17 cell recruitment. Jci Insight. PMID 32554933 DOI: 10.1172/Jci.Insight.137858  0.536
2020 Ganatra SR, Bucsan AN, Alvarez X, Kumar S, Chatterjee A, Quezada M, Fish AI, Singh DK, Singh B, Sharan R, Lee TH, Shanmugasundaram U, Velu V, Khader SA, Mehra S, ... Rengarajan J, et al. Anti-retroviral therapy does not reduce tuberculosis reactivation in a tuberculosis-HIV co-infection model. The Journal of Clinical Investigation. PMID 32544085 DOI: 10.1172/Jci136502  0.424
2020 Collins JM, Siddiqa A, Jones DP, Liu K, Kempker RR, Nizam A, Shah NS, Ismail N, Ouma SG, Tukvadze N, Li S, Day CL, Rengarajan J, Brust JCM, Gandhi NR, et al. Tryptophan catabolism reflects disease activity in human tuberculosis. Jci Insight. PMID 32369456 DOI: 10.1172/Jci.Insight.137131  0.447
2019 Silveira-Mattos PS, Barreto-Duarte B, Vasconcelos B, Fukutani KF, Vinhaes CL, Oliveira-de-Souza D, Ibegbu CC, Figueiredo MC, Sterling TR, Rengarajan J, Andrade BB. Differential expression of activation markers by Mycobacterium tuberculosis-specific CD4+ T-cell distinguishes extrapulmonary from pulmonary tuberculosis and latent infection. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 31665254 DOI: 10.1093/Cid/Ciz1070  0.458
2019 Foreman TW, Bucşan AN, Mehra S, Peloquin C, Doyle LA, Russell-Lodrigue K, Gandhi NR, Altman J, Day CL, Ernst JD, Blumberg HM, Rengarajan J, Kaushal D. Isoniazid and Rifapentine Treatment Eradicates Persistent in Macaques. American Journal of Respiratory and Critical Care Medicine. PMID 31647877 DOI: 10.1164/Rccm.201903-0646Oc  0.389
2019 Bucşan AN, Chatterjee A, Singh DK, Foreman TW, Lee TH, Threeton B, Kirkpatrick MG, Ahmed M, Golden N, Alvarez X, Hoxie JA, Mehra S, Rengarajan J, Khader SA, Kaushal D. Mechanisms of reactivation of latent tuberculosis infection due to SIV co-infection. The Journal of Clinical Investigation. PMID 31479428 DOI: 10.1172/Jci125810  0.467
2019 Sia JK, Rengarajan J. Immunology of Infections. Microbiology Spectrum. 7. PMID 31298204 DOI: 10.1128/Microbiolspec.Gpp3-0022-2018  0.447
2019 Bucsan AN, Rout N, Foreman TW, Khader SA, Rengarajan J, Kaushal D. Mucosal-activated invariant T cells do not exhibit significant lung recruitment and proliferation profiles in macaques in response to infection with Mycobacterium tuberculosis CDC1551. Tuberculosis (Edinburgh, Scotland). PMID 31072689 DOI: 10.1016/J.Tube.2019.04.006  0.485
2018 Keshavjee S, Amanullah F, Cattamanchi A, Chaisson R, Dobos KM, Fox GJ, Gendelman HE, Gordon R, Hesseling A, Hoi LV, Kampmann B, Kana B, Khuller G, Lewinsohn DM, Lewinsohn DA, ... ... Rengarajan J, et al. Moving Toward Tuberculosis Elimination: Critical Issues for Research in Diagnostics and Therapeutics for Tuberculosis Infection. American Journal of Respiratory and Critical Care Medicine. PMID 30335466 DOI: 10.1164/Rccm.201806-1053Pp  0.409
2018 Adekambi T, Ibegbu CC, Cagle S, Ray SM, Rengarajan J. High Frequencies of Caspase-3 Expressing -Specific CD4 T Cells Are Associated With Active Tuberculosis. Frontiers in Immunology. 9: 1481. PMID 29983703 DOI: 10.3389/Fimmu.2018.01481  0.499
2018 Whatney WE, Gandhi NR, Lindestam Arlehamn CS, Nizam A, Wu H, Quezada MJ, Campbell A, Allana S, Kabongo MM, Khayumbi J, Muchiri B, Ongalo J, Tonui J, Sasser LE, Fergus TJ, ... ... Rengarajan J, et al. A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in HumanInfection. Journal of Immunology (Baltimore, Md. : 1950). PMID 29540577 DOI: 10.4049/Jimmunol.1701737  0.417
2017 Bizzell E, Sia JK, Quezada M, Enriquez A, Georgieva M, Rengarajan J. Deletion of BCG Hip1 protease enhances dendritic cell and CD4 T cell responses. Journal of Leukocyte Biology. PMID 29345365 DOI: 10.1002/Jlb.4A0917-363Rr  0.475
2017 Gautam US, Foreman TW, Bucsan AN, Veatch AV, Alvarez X, Adekambi T, Golden NA, Gentry KM, Doyle-Meyers LA, Russell-Lodrigue KE, Didier PJ, Blanchard JL, Kousoulas KG, Lackner AA, Kalman D, ... Rengarajan J, et al. In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29255022 DOI: 10.1073/Pnas.1711373114  0.516
2017 Georgieva M, Sia JK, Bizzell E, Madan-Lala R, Rengarajan J. Mycobacterium tuberculosis GroEL2 modulates dendritic cell responses. Infection and Immunity. PMID 29133346 DOI: 10.1128/Iai.00387-17  0.491
2017 Schechter MC, Buac K, Adekambi T, Cagle S, Celli J, Ray SM, Mehta CC, Rada B, Rengarajan J. Neutrophil extracellular trap (NET) levels in human plasma are associated with active TB. Plos One. 12: e0182587. PMID 28777804 DOI: 10.1371/Journal.Pone.0182587  0.374
2017 Sia JK, Bizzell E, Madan-Lala R, Rengarajan J. Engaging the CD40-CD40L pathway augments T-helper cell responses and improves control of Mycobacterium tuberculosis infection. Plos Pathogens. 13: e1006530. PMID 28767735 DOI: 10.1371/Journal.Ppat.1006530  0.492
2017 Naffin-Olivos JL, Daab A, White A, Goldfarb NE, Milne AC, Liu D, Baikovitz J, Dunn BM, Rengarajan J, Petsko GA, Ringe D. Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c). Biochemistry. PMID 28346784 DOI: 10.1021/Acs.Biochem.6B01066  0.396
2015 Kaushal D, Foreman TW, Gautam US, Alvarez X, Adekambi T, Rangel-Moreno J, Golden NA, Johnson AM, Phillips BL, Ahsan MH, Russell-Lodrigue KE, Doyle LA, Roy CJ, Didier PJ, Blanchard JL, ... Rengarajan J, et al. Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis. Nature Communications. 6: 8533. PMID 26460802 DOI: 10.1038/Ncomms9533  0.404
2015 Adekambi T, Ibegbu CC, Cagle S, Kalokhe AS, Wang YF, Hu Y, Day CL, Ray SM, Rengarajan J. Biomarkers on patient T cells diagnose active tuberculosis and monitor treatment response. The Journal of Clinical Investigation. 125: 3723. PMID 26325038 DOI: 10.1172/Jci83279  0.319
2015 Sia JK, Georgieva M, Rengarajan J. Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells. Journal of Immunology Research. 2015: 747543. PMID 26258152 DOI: 10.1155/2015/747543  0.475
2015 Adekambi T, Ibegbu CC, Cagle S, Kalokhe AS, Wang YF, Hu Y, Day CL, Ray SM, Rengarajan J. Biomarkers on patient T cells diagnose active tuberculosis and monitor treatment response. The Journal of Clinical Investigation. 125: 1827-38. PMID 25822019 DOI: 10.1172/Jci77990  0.488
2015 Gautam US, McGillivray A, Mehra S, Didier PJ, Midkiff CC, Kissee RS, Golden NA, Alvarez X, Niu T, Rengarajan J, Sherman DR, Kaushal D. DosS Is Required for the Complete Virulence of Mycobacterium tuberculosis in Mice with Classical Granulomatous Lesions. American Journal of Respiratory Cell and Molecular Biology. 52: 708-16. PMID 25322074 DOI: 10.1165/Rcmb.2014-0230Oc  0.395
2015 Kalokhe AS, Adekambi T, Ibegbu CC, Ray SM, Day CL, Rengarajan J. Impaired degranulation and proliferative capacity of Mycobacterium tuberculosis-specific CD8+ T cells in HIV-infected individuals with latent tuberculosis. The Journal of Infectious Diseases. 211: 635-40. PMID 25205634 DOI: 10.1093/Infdis/Jiu505  0.428
2015 Schechter MC, Ibegbu CC, Adekambi T, Cagle S, Ray SM, Rengarajan J. Investigation of Plasma IP-10 During Treatment of Pulmonary Tuberculosis Open Forum Infectious Diseases. 2. DOI: 10.1093/Ofid/Ofv133.597  0.315
2014 Naffin-Olivos JL, Georgieva M, Goldfarb N, Madan-Lala R, Dong L, Bizzell E, Valinetz E, Brandt GS, Yu S, Shabashvili DE, Ringe D, Dunn BM, Petsko GA, Rengarajan J. Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2. Plos Pathogens. 10: e1004132. PMID 24830429 DOI: 10.1371/Journal.Ppat.1004132  0.452
2014 Madan-Lala R, Sia JK, King R, Adekambi T, Monin L, Khader SA, Pulendran B, Rengarajan J. Mycobacterium tuberculosis impairs dendritic cell functions through the serine hydrolase Hip1. Journal of Immunology (Baltimore, Md. : 1950). 192: 4263-72. PMID 24659689 DOI: 10.4049/Jimmunol.1303185  0.504
2013 Jung JY, Madan-Lala R, Georgieva M, Rengarajan J, Sohaskey CD, Bange FC, Robinson CM. The intracellular environment of human macrophages that produce nitric oxide promotes growth of mycobacteria. Infection and Immunity. 81: 3198-209. PMID 23774601 DOI: 10.1128/Iai.00611-13  0.378
2012 Ernst JD, Hanekom W, Hawn T, Kampmann B, Rengarajan J. Meeting report: The International Conference on Human Immunity to Tuberculosis. Tuberculosis (Edinburgh, Scotland). 92: 440-4. PMID 22658910 DOI: 10.1016/J.Tube.2012.05.003  0.396
2012 Adekambi T, Ibegbu CC, Kalokhe AS, Yu T, Ray SM, Rengarajan J. Distinct effector memory CD4+ T cell signatures in latent Mycobacterium tuberculosis infection, BCG vaccination and clinically resolved tuberculosis. Plos One. 7: e36046. PMID 22545156 DOI: 10.1371/Journal.Pone.0036046  0.412
2011 Madan-Lala R, Peixoto KV, Re F, Rengarajan J. Mycobacterium tuberculosis Hip1 dampens macrophage proinflammatory responses by limiting toll-like receptor 2 activation. Infection and Immunity. 79: 4828-38. PMID 21947769 DOI: 10.1128/Iai.05574-11  0.467
2010 Rengarajan J, Adekambi T, Ibegbu C, Ray S. CD4+ Memory Responses in Latent Tuberculosis Clinical Immunology. 135: S113. DOI: 10.1016/J.Clim.2010.03.337  0.341
2008 Rengarajan J, Murphy E, Park A, Krone CL, Hett EC, Bloom BR, Glimcher LH, Rubin EJ. Mycobacterium tuberculosis Rv2224c modulates innate immune responses. Proceedings of the National Academy of Sciences of the United States of America. 105: 264-9. PMID 18172199 DOI: 10.1073/Pnas.0710601105  0.587
2005 Rengarajan J, Bloom BR, Rubin EJ. Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages. Proceedings of the National Academy of Sciences of the United States of America. 102: 8327-32. PMID 15928073 DOI: 10.1073/Pnas.0503272102  0.39
2002 Rengarajan J, Mowen KA, McBride KD, Smith ED, Singh H, Glimcher LH. Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. The Journal of Experimental Medicine. 195: 1003-12. PMID 11956291 DOI: 10.1084/Jem.20011128  0.568
2002 Rengarajan J, Tang B, Glimcher LH. NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells. Nature Immunology. 3: 48-54. PMID 11740499 DOI: 10.1038/Ni744  0.554
2000 Rengarajan J, Szabo SJ, Glimcher LH. Transcriptional regulation of Th1/Th2 polarization. Immunology Today. 21: 479-83. PMID 11071525 DOI: 10.1016/S0167-5699(00)01712-6  0.54
2000 Rengarajan J, Mittelstadt PR, Mages HW, Gerth AJ, Kroczek RA, Ashwell JD, Glimcher LH. Sequential involvement of NFAT and Egr transcription factors in FasL regulation. Immunity. 12: 293-300. PMID 10755616 DOI: 10.1016/S1074-7613(00)80182-X  0.547
1998 Ranger AM, Oukka M, Rengarajan J, Glimcher LH. Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development. Immunity. 9: 627-35. PMID 9846484 DOI: 10.1016/S1074-7613(00)80660-3  0.547
1996 Hodge MR, Chun HJ, Rengarajan J, Alt A, Lieberson R, Glimcher LH. NF-AT-Driven interleukin-4 transcription potentiated by NIP45. Science (New York, N.Y.). 274: 1903-5. PMID 8943202 DOI: 10.1126/Science.274.5294.1903  0.52
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