Harsh B. Pathak, Ph.D. - Publications

Affiliations: 
2006 Pennsylvania State University, State College, PA, United States 
Area:
Microbiology Biology, Molecular Biology, Virology Biology

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Pathak HB, Zhou Y, Sethi G, Hirst J, Schilder RJ, Golemis EA, Godwin AK. A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer. Plos One. 10: e0144126. PMID 26637171 DOI: 10.1371/Journal.Pone.0144126  0.64
2015 Rebbeck TR, Mitra N, Wan F, Sinilnikova OM, Healey S, McGuffog L, Mazoyer S, Chenevix-Trench G, Easton DF, Antoniou AC, Nathanson KL, Laitman Y, Kushnir A, Paluch-Shimon S, ... ... Pathak H, et al. Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer. Jama. 313: 1347-61. PMID 25849179 DOI: 10.1001/Jama.2014.5985  0.64
2014 Sethi G, Kwon Y, Burkhalter RJ, Pathak HB, Madan R, McHugh S, Atay S, Murthy S, Tawfik OW, Godwin AK. PTN signaling: Components and mechanistic insights in human ovarian cancer. Molecular Carcinogenesis. PMID 25418856 DOI: 10.1002/Mc.22249  0.64
2014 Fang CY, Ross EA, Pathak HB, Godwin AK, Tseng M. Acculturative stress and inflammation among Chinese immigrant women. Psychosomatic Medicine. 76: 320-6. PMID 24846001 DOI: 10.1097/PSY.0000000000000065  0.64
2014 Do TV, Xiao F, Bickel LE, Klein-Szanto AJ, Pathak HB, Hua X, Howe C, O'Brien SW, Maglaty M, Ecsedy JA, Litwin S, Golemis EA, Schilder RJ, Godwin AK, Connolly DC. Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion. Oncogene. 33: 539-49. PMID 23334327 DOI: 10.1038/Onc.2012.632  0.64
2012 Sethi G, Pathak HB, Zhang H, Zhou Y, Einarson MB, Vathipadiekal V, Gunewardena S, Birrer MJ, Godwin AK. An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer. Plos One. 7: e47086. PMID 23056589 DOI: 10.1371/Journal.Pone.0047086  0.64
2012 Schilder RJ, Brady WE, Lankes HA, Fiorica JV, Shahin MS, Zhou XC, Mannel RS, Pathak HB, Hu W, Alpaugh RK, Sood AK, Godwin AK. Phase II evaluation of dasatinib in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: a Gynecologic Oncology Group study. Gynecologic Oncology. 127: 70-4. PMID 22710075 DOI: 10.1016/j.ygyno.2012.06.009  0.64
2012 Stevens KN, Fredericksen Z, Vachon CM, Wang X, Margolin S, Lindblom A, Nevanlinna H, Greco D, Aittomäki K, Blomqvist C, Chang-Claude J, Vrieling A, Flesch-Janys D, Sinn HP, Wang-Gohrke S, ... ... Pathak HB, et al. 19p13.1 is a triple-negative-specific breast cancer susceptibility locus. Cancer Research. 72: 1795-803. PMID 22331459 DOI: 10.1158/0008-5472.Can-11-3364  0.64
2012 Ratushny V, Pathak HB, Beeharry N, Tikhmyanova N, Xiao F, Li T, Litwin S, Connolly DC, Yen TJ, Weiner LM, Godwin AK, Golemis EA. Dual inhibition of SRC and Aurora kinases induces postmitotic attachment defects and cell death. Oncogene. 31: 1217-27. PMID 21785464 DOI: 10.1038/Onc.2011.314  0.64
2011 Sasaroli D, Gimotty PA, Pathak HB, Hammond R, Kougioumtzidou E, Katsaros D, Buckanovich R, Devarajan K, Sandaltzopoulos R, Godwin AK, Scholler N, Coukos G. Novel surface targets and serum biomarkers from the ovarian cancer vasculature. Cancer Biology & Therapy. 12: 169-80. PMID 21617380 DOI: 10.4161/Cbt.12.3.16260  0.64
2009 Oh HS, Pathak HB, Goodfellow IG, Arnold JJ, Cameron CE. Insight into poliovirus genome replication and encapsidation obtained from studies of 3B-3C cleavage site mutants. Journal of Virology. 83: 9370-87. PMID 19587035 DOI: 10.1128/Jvi.02076-08  0.64
2009 Schilder RJ, Pathak HB, Lokshin AE, Holloway RW, Alvarez RD, Aghajanian C, Min H, Devarajan K, Ross E, Drescher CW, Godwin AK. Phase II trial of single agent cetuximab in patients with persistent or recurrent epithelial ovarian or primary peritoneal carcinoma with the potential for dose escalation to rash. Gynecologic Oncology. 113: 21-7. PMID 19162309 DOI: 10.1200/Jco.2007.25.18_Suppl.5577  0.64
2008 Pathak HB, Oh HS, Goodfellow IG, Arnold JJ, Cameron CE. Picornavirus genome replication: roles of precursor proteins and rate-limiting steps in oriI-dependent VPg uridylylation. The Journal of Biological Chemistry. 283: 30677-88. PMID 18779320 DOI: 10.1074/Jbc.M806101200  0.64
2008 Shen M, Reitman ZJ, Zhao Y, Moustafa I, Wang Q, Arnold JJ, Pathak HB, Cameron CE. Picornavirus genome replication. Identification of the surface of the poliovirus (PV) 3C dimer that interacts with PV 3Dpol during VPg uridylylation and construction of a structural model for the PV 3C2-3Dpol complex. The Journal of Biological Chemistry. 283: 875-88. PMID 17993457 DOI: 10.1074/Jbc.M707907200  0.64
2007 Shen M, Wang Q, Yang Y, Pathak HB, Arnold JJ, Castro C, Lemon SM, Cameron CE. Human rhinovirus type 14 gain-of-function mutants for oriI utilization define residues of 3C(D) and 3Dpol that contribute to assembly and stability of the picornavirus VPg uridylylation complex. Journal of Virology. 81: 12485-95. PMID 17855535 DOI: 10.1128/Jvi.00972-07  0.64
2007 Pathak HB, Arnold JJ, Wiegand PN, Hargittai MR, Cameron CE. Picornavirus genome replication: assembly and organization of the VPg uridylylation ribonucleoprotein (initiation) complex. The Journal of Biological Chemistry. 282: 16202-13. PMID 17392285 DOI: 10.1074/Jbc.M610608200  0.64
2007 Marcotte LL, Wass AB, Gohara DW, Pathak HB, Arnold JJ, Filman DJ, Cameron CE, Hogle JM. Crystal structure of poliovirus 3CD protein: virally encoded protease and precursor to the RNA-dependent RNA polymerase. Journal of Virology. 81: 3583-96. PMID 17251299 DOI: 10.1128/Jvi.02306-06  0.64
2005 Franco D, Pathak HB, Cameron CE, Rombaut B, Wimmer E, Paul AV. Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Virology Journal. 2: 86. PMID 16300678 DOI: 10.1186/1743-422X-2-86  0.64
2005 Franco D, Pathak HB, Cameron CE, Rombaut B, Wimmer E, Paul AV. Stimulation of poliovirus synthesis in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDpro. Journal of Virology. 79: 6358-67. PMID 15858019 DOI: 10.1128/Jvi.79.10.6358-6367.2005  0.64
2002 Pathak HB, Ghosh SK, Roberts AW, Sharma SD, Yoder JD, Arnold JJ, Gohara DW, Barton DJ, Paul AV, Cameron CE. Structure-function relationships of the RNA-dependent RNA polymerase from poliovirus (3Dpol). A surface of the primary oligomerization domain functions in capsid precursor processing and VPg uridylylation. The Journal of Biological Chemistry. 277: 31551-62. PMID 12077141 DOI: 10.1074/Jbc.M204408200  0.64
2001 Wei L, Huhn JS, Mory A, Pathak HB, Sosnovtsev SV, Green KY, Cameron CE. Proteinase-polymerase precursor as the active form of feline calicivirus RNA-dependent RNA polymerase. Journal of Virology. 75: 1211-9. PMID 11152494 DOI: 10.1128/Jvi.75.3.1211-1219.2001  0.64
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